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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Palbinone
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Accession:CHEBI:69584 term browser browse the term
Definition:A 16-oxo steroid that has formula C22H30O4.
Synonyms:related_synonym: 18-Norandrosta-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,14-tetramethyl-, (3beta,5alpha)-;   Formula=C22H30O4;   InChI=1S/C22H30O4/c1-19(2)13-8-11-21(4)14(20(13,3)10-9-15(19)23)7-6-12-16(24)17(25)18(26)22(12,21)5/h6-7,13-15,23-24H,8-11H2,1-5H3/t13-,14+,15-,20-,21+,22-/m0/s1;   InChIKey=KIAKLFLISZCITK-PPAUHQMUSA-N;   SMILES=[H][C@@]12CC[C@]3(C)[C@]([H])(C=CC4=C(O)C(=O)C(=O)[C@@]34C)[C@@]1(C)CC[C@H](O)C2(C)C
 xref: CAS:139954-00-0
 xref_mesh: MESH:C080910
 xref: PMID:21954959


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Palbinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein] CTD PMID:32202043 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Cat catalase multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:32202043 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA] CTD PMID:32202043 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il18 interleukin 18 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:32202043 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of IL1B protein] CTD PMID:32202043 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA] CTD PMID:32202043 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein] CTD PMID:32202043 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of PYCARD protein] CTD PMID:32202043 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        biochemical role 19381
          metabolite 19356
            Palbinone 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      ketone 16924
                                        oxo steroid 9718
                                          16-oxo steroid 8
                                            Palbinone 8
paths to the root