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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cannabidiol
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Accession:CHEBI:69478 term browser browse the term
Definition:An cannabinoid that is cyclohexene which is substituted by a methyl group at position 1, a 2,6-dihydroxy-4-pentylphenyl group at position 3, and a prop-1-en-2-yl group at position 4.
Synonyms:exact_synonym: (1'R,2'R)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydrobiphenyl-2,6-diol
 related_synonym: (-)-CBD;   (-)-trans-2-p-mentha-1,8-dien-3-yl-5-pentylresorcinol;   (-)-trans-cannabidiol;   Delta(1(2))-trans-cannabidiol;   Formula=C21H30O2;   InChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1;   InChIKey=QHMBSVQNZZTUGM-ZWKOTPCHSA-N;   SMILES=[H][C@]1(CCC(C)=C[C@H]1C1=C(O)C=C(CCCCC)C=C1O)C(C)=C;   cannabidiolum
 alt_id: CHEBI:3358
 xref: CAS:13956-29-1;   DrugBank:DB09061;   Drug_Central:5288;   KEGG:C07578;   KNApSAcK:C00002641;   LIPID_MAPS_instance:LMPK13120001
 xref_mesh: MESH:D002185
 xref: MetaCyc:CPD-7173;   PDBeChem:P0T;   PMID:25703248;   PMID:26845349;   PMID:26976797;   PMID:27067870;   PMID:27157263;   PMID:27215129;   PMID:27267317;   PMID:27285147;   PMID:27344041;   PMID:27374322;   PMID:27430346;   PMID:27471947;   PMID:27506704;   PMID:31566564;   Patent:US2304669;   Reaxys:2222023;   Wikipedia:Cannabidiol


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cannabidiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of ABL2 mRNA CTD PMID:26504004 NCBI chr13:68,673,702...68,839,742
Ensembl chr13:68,673,722...68,839,742
JBrowse link
G Actn1 actinin, alpha 1 affects methylation EXP Cannabidiol affects the methylation of ACTN1 gene CTD PMID:30521419 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Adcy5 adenylate cyclase 5 increases expression ISO Cannabidiol results in increased expression of ADCY5 mRNA CTD PMID:33019509 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adcy9 adenylate cyclase 9 decreases expression ISO Cannabidiol results in decreased expression of ADCY9 mRNA CTD PMID:33019509 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
JBrowse link
G Adrb1 adrenoceptor beta 1 decreases expression EXP Cannabidiol results in decreased expression of ADRB1 protein CTD PMID:33338514 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Agtrap angiotensin II receptor-associated protein increases expression ISO Cannabidiol results in increased expression of AGTRAP mRNA CTD PMID:30742662 NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036
JBrowse link
G Aicda activation-induced cytidine deaminase increases expression
multiple interactions
ISO Cannabidiol results in increased expression of AICDA mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of AICDA mRNA
CTD PMID:30742662 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 increases expression ISO Cannabidiol results in increased expression of AKR1B7 mRNA CTD PMID:21542829 NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
affects expression
multiple interactions
increases expression
ISO Cannabidiol results in decreased phosphorylation of AKT1 protein
Cannabidiol affects the expression of AKT1 protein
tanespimycin affects the reaction [Cannabidiol affects the expression of AKT1 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of AKT1 protein]
Cannabidiol results in increased expression of AKT1 mRNA
CTD PMID:26504004 PMID:28392768 PMID:33019509 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Angpt1 angiopoietin 1 increases secretion ISO Cannabidiol results in increased secretion of ANGPT1 protein CTD PMID:32656944 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Angptl6 angiopoietin-like 6 increases expression ISO Cannabidiol results in increased expression of ANGPTL6 mRNA CTD PMID:21542829 NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 affects methylation EXP Cannabidiol affects the methylation of APC2 gene CTD PMID:30521419 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Cannabidiol inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GABRA1 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GRIA2 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of SNAP25 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of DLG4 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [APP gene mutant form co-treated with PSEN1 gene mutant form]
CTD PMID:21350020 PMID:27567873 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [Cannabidiol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA] CTD PMID:31054246 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Aqp4 aquaporin 4 affects expression ISO Cannabidiol affects the expression of AQP4 mRNA CTD PMID:31054246 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Aqp9 aquaporin 9 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of AQP9 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of AQP9 mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A affects methylation EXP Cannabidiol affects the methylation of ARPC1A gene CTD PMID:30521419 NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330
JBrowse link
G Arrb2 arrestin, beta 2 affects methylation EXP Cannabidiol affects the methylation of ARRB2 gene CTD PMID:30521419 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO Cannabidiol results in increased expression of ASB2 mRNA CTD PMID:27256343 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions
increases expression
ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of ASNS mRNA
Cannabidiol results in increased expression of ASNS mRNA
CTD PMID:26504004 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of ATF3 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of ATF3 mRNA
Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of ATF3 mRNA]
CTD PMID:21542829 PMID:26504004 PMID:27256343 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Cannabidiol results in increased expression of ATF4 mRNA CTD PMID:21542829 PMID:33019509 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO Cannabidiol results in increased expression of ATF5 mRNA CTD PMID:21542829 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG12 mRNA] CTD PMID:30074247 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG4B mRNA] CTD PMID:30074247 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Cannabidiol results in increased expression of ATP2A3 mRNA CTD PMID:21542829 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Avil advillin increases expression ISO Cannabidiol results in increased expression of AVIL mRNA CTD PMID:21542829 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
JBrowse link
G Axin2 axin 2 affects methylation EXP Cannabidiol affects the methylation of AXIN2 gene CTD PMID:30521419 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Cannabidiol results in increased expression of AXL mRNA CTD PMID:30742662 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of BACH1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of BACH1 mRNA
CTD PMID:30742662 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Cannabidiol inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:27430346 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Cannabidiol results in increased expression of BCL2L1 mRNA CTD PMID:33019509 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Cannabidiol results in increased expression of BDNF protein CTD PMID:19939866 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of BECN1 mRNA] CTD PMID:30074247 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO Cannabidiol results in increased expression of BGLAP protein CTD PMID:32656944 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bmp6 bone morphogenetic protein 6 affects methylation EXP Cannabidiol affects the methylation of BMP6 gene CTD PMID:30521419 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bmp7 bone morphogenetic protein 7 affects methylation EXP Cannabidiol affects the methylation of BMP7 gene CTD PMID:30521419 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Bsg basigin (Ok blood group) decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of BSG mRNA
[Dronabinol co-treated with Cannabidiol] results in decreased expression of BSG mRNA; Cannabidiol promotes the reaction [Dronabinol results in decreased expression of BSG mRNA]; carfilzomib promotes the reaction [[Dronabinol co-treated with Cannabidiol] results in decreased expression of BSG mRNA]; Dronabinol promotes the reaction [Cannabidiol results in decreased expression of BSG mRNA]
CTD PMID:27769052 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Btla B and T lymphocyte associated multiple interactions
increases expression
ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of BTLA mRNA]
Cannabidiol results in increased expression of BTLA mRNA
CTD PMID:27256343 NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181
JBrowse link
G C1qa complement C1q A chain decreases expression ISO Cannabidiol results in decreased expression of C1QA mRNA CTD PMID:21542829 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A affects methylation EXP Cannabidiol affects the methylation of CACNA1A gene CTD PMID:30521419 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G affects methylation EXP Cannabidiol affects the methylation of CACNA1G gene CTD PMID:30521419 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I affects methylation EXP Cannabidiol affects the methylation of CACNA1I gene CTD PMID:30521419 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects methylation EXP Cannabidiol affects the methylation of CACNA2D1 gene CTD PMID:30521419 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 affects methylation EXP Cannabidiol affects the methylation of CACNA2D2 gene CTD PMID:30521419 NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression ISO Cannabidiol results in decreased expression of CAMK2B mRNA CTD PMID:33019509 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO Cannabidiol results in increased expression of CARS mRNA CTD PMID:21542829 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO
EXP
[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein; [Cannabidiol co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [Cannabidiol results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [Cannabidiol results in increased cleavage of CASP3 protein]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 mRNA]
CTD PMID:27430346 PMID:32708634 PMID:32733202 PMID:33076330 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression ISO Cannabidiol results in increased expression of CASP4 mRNA CTD PMID:21542829 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 decreases expression ISO Cannabidiol results in decreased expression of CASP6 mRNA CTD PMID:33019509 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp8 caspase 8 decreases expression ISO Cannabidiol results in decreased expression of CASP8 mRNA CTD PMID:33019509 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase decreases activity ISO Cannabidiol results in decreased activity of CAT protein CTD PMID:32752303 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CCL2 mRNA
Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]
CTD PMID:19910459 PMID:21542829 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CCL22 mRNA CTD PMID:30742662 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 decreases expression ISO Cannabidiol results in decreased expression of CCL6 mRNA CTD PMID:21542829 NCBI chr10:68,381,179...68,385,811
Ensembl chr10:68,380,188...68,384,001
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO Cannabidiol results in decreased expression of CCL7 mRNA CTD PMID:21542829 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CCND1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CCND1 mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Cannabidiol results in decreased expression of CCNE1 mRNA CTD PMID:21542829 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CCNE2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CCNE2 mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd274 CD274 molecule increases expression ISO Cannabidiol results in increased expression of CD274 mRNA CTD PMID:21542829 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CD69 mRNA] CTD PMID:27256343 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Cdc25a cell division cycle 25A decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CDC25A mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CDC25A mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Cannabidiol results in decreased expression of CDC6 mRNA CTD PMID:21542829 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA] CTD PMID:32049991 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects expression
multiple interactions
ISO Cannabidiol affects the expression of CDK1 protein
tanespimycin affects the reaction [Cannabidiol affects the expression of CDK1 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of CDK1 protein]
CTD PMID:26504004 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CDK5R1 mRNA] CTD PMID:27256343 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO Cannabidiol results in increased expression of CDKN1A mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CDKN1A mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
decreases expression
ISO
EXP
Cannabidiol results in increased expression of CDKN2A mRNA
Cannabidiol results in decreased expression of CDKN2A mRNA
CTD PMID:21542829 PMID:32553926 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO Cannabidiol results in increased expression of CDKN2B mRNA CTD PMID:21542829 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CEBPB mRNA
Cannabidiol results in increased expression of CEBPB mRNA
CTD PMID:30742662 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Cannabidiol results in increased expression of CFLAR mRNA CTD PMID:30742662 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of CHAC1 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of CHAC1 mRNA
CTD PMID:21542829 PMID:26504004 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 increases expression ISO Cannabidiol results in increased expression of CHD2 mRNA CTD PMID:21542829 NCBI chr 1:127,188,146...127,317,041
Ensembl chr 1:127,190,059...127,300,502
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CHRNA2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CHRNA2 mRNA
CTD PMID:30742662 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
JBrowse link
G Chst10 carbohydrate sulfotransferase 10 decreases expression ISO Cannabidiol results in decreased expression of CHST10 mRNA CTD PMID:21542829 NCBI chr 9:41,092,805...41,122,737
Ensembl chr 9:41,092,808...41,122,503
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression ISO Cannabidiol results in increased expression of CISH mRNA CTD PMID:30742662 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Cldn1 claudin 1 increases expression ISO Cannabidiol results in increased expression of CLDN1 protein CTD PMID:32656944 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Cldn4 claudin 4 increases expression ISO Cannabidiol results in increased expression of CLDN4 protein CTD PMID:32656944 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO Cannabidiol results in increased expression of CLEC4E mRNA CTD PMID:21542829 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
JBrowse link
G Clock clock circadian regulator decreases expression ISO Cannabidiol results in decreased expression of CLOCK mRNA CTD PMID:33019509 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CMPK2 mRNA] CTD PMID:27256343 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
affects response to substance
ISO
EXP
CNR1 polymorphism affects the susceptibility to [Dronabinol co-treated with Cannabidiol]; CNR1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]
Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]
[1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene co-treated with CNR1 protein] affects the susceptibility to Cannabidiol
CNR1 protein affects the susceptibility to Cannabidiol
CTD PMID:20668920 PMID:30550613 PMID:31013550 PMID:31202911 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
affects expression
ISO CNR2 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]
Cannabidiol affects the expression of CNR2 mRNA
CTD PMID:20668920 PMID:32733202 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Cannabidiol results in increased expression of COL1A1 protein CTD PMID:32656944 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression ISO Cannabidiol results in increased expression of COL4A1 mRNA CTD PMID:21542829 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression ISO Cannabidiol results in increased expression of COX6A2 mRNA CTD PMID:21542829 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Cpd carboxypeptidase D multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CPD mRNA CTD PMID:30742662 NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491
JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 increases expression ISO Cannabidiol results in increased expression of CPEB1 mRNA CTD PMID:21542829 NCBI chr 1:135,300,048...135,407,688
Ensembl chr 1:135,300,461...135,409,760
JBrowse link
G Crb1 crumbs cell polarity complex component 1 affects methylation EXP Cannabidiol affects the methylation of CRB1 gene CTD PMID:30521419 NCBI chr13:50,801,484...50,989,261
Ensembl chr13:50,800,959...50,989,261
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
decreases expression
multiple interactions
ISO Cannabidiol results in increased phosphorylation of CREB1 protein
Cannabidiol results in decreased expression of CREB1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [Cannabidiol results in increased phosphorylation of CREB1 protein]
CTD PMID:28601556 PMID:33019509 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CREM mRNA] CTD PMID:27256343 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha affects methylation EXP Cannabidiol affects the methylation of CSF2RA gene CTD PMID:30521419 NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128
JBrowse link
G Csnk1e casein kinase 1, epsilon affects methylation EXP Cannabidiol affects the methylation of CSNK1E gene CTD PMID:30521419 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CSRNP1 mRNA] CTD PMID:27256343 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Cth cystathionine gamma-lyase multiple interactions
increases expression
ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of CTH mRNA
Cannabidiol results in increased expression of CTH mRNA
CTD PMID:26504004 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctsg cathepsin G increases expression ISO Cannabidiol results in increased expression of CTSG mRNA CTD PMID:21542829 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases expression ISO Cannabidiol results in decreased expression of CX3CR1 mRNA CTD PMID:21542829 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 protein]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 protein]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] CTD PMID:32244040 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO Cannabidiol results in decreased expression of CXCL14 mRNA CTD PMID:21542829 NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCL9 mRNA] CTD PMID:27256343 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCR1 mRNA] CTD PMID:27256343 NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CXCR4 mRNA
[Dronabinol co-treated with Cannabidiol] results in decreased expression of CXCR4 mRNA; carfilzomib promotes the reaction [[Dronabinol co-treated with Cannabidiol] results in decreased expression of CXCR4 mRNA]
Cannabidiol results in increased expression of CXCR4 mRNA
CTD PMID:27769052 PMID:30742662 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO Cannabidiol results in decreased activity of CYP19A1 protein
Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA]
CTD PMID:31953017 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Cannabidiol results in decreased activity of CYP1A1 protein CTD PMID:24667653 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Cannabidiol results in decreased activity of CYP1A2 protein CTD PMID:24667653 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity ISO Cannabidiol results in decreased activity of CYP2B10 CTD PMID:8043019 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity ISO Cannabidiol results in decreased activity of CYP2B6 protein CTD PMID:24667653 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity ISO Cannabidiol results in decreased activity of CYP2C9 protein CTD PMID:24667653 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO Cannabidiol results in decreased activity of CYP2C19 protein CTD PMID:24667653 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Cannabidiol results in decreased activity of CYP2D6 protein CTD PMID:24667653 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Cannabidiol results in decreased activity of CYP3A4 protein CTD PMID:24667653 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases activity ISO Cannabidiol results in decreased activity of CYP3A5 protein CTD PMID:24667653 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyrib CYFIP related Rac1 interactor B decreases expression ISO Cannabidiol results in decreased expression of CYRIB mRNA CTD PMID:21542829 NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686
JBrowse link
G Cytip cytohesin 1 interacting protein decreases expression ISO Cannabidiol results in decreased expression of CYTIP mRNA CTD PMID:21542829 NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
JBrowse link
G Dapk3 death-associated protein kinase 3 affects methylation EXP Cannabidiol affects the methylation of DAPK3 gene CTD PMID:30521419 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558
JBrowse link
G Dct dopachrome tautomerase increases expression
multiple interactions
ISO Cannabidiol results in increased expression of DCT mRNA; Cannabidiol results in increased expression of DCT protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of DCT mRNA]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of DCT mRNA]
CTD PMID:28601556 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of DDIT3 mRNA
Cannabidiol results in increased expression of DDIT3 mRNA; Cannabidiol results in increased expression of DDIT3 protein
[Dronabinol co-treated with Cannabidiol] results in increased expression of DDIT3 mRNA
[Bilirubin co-treated with Rotenone] promotes the reaction [Cannabidiol results in increased expression of DDIT3 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of DDIT3 mRNA]; Rotenone promotes the reaction [Cannabidiol results in increased expression of DDIT3 mRNA]
CTD PMID:21542829 PMID:26504004 PMID:29441458 PMID:32033040 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of DDIT4 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of DDIT4 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of DDIT4 mRNA
CTD PMID:21542829 PMID:26504004 PMID:30742662 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression ISO Cannabidiol results in increased expression of DDR1 mRNA CTD PMID:27256343 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of DGAT1 mRNA] CTD PMID:27256343 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects methylation
multiple interactions
EXP
ISO
Cannabidiol affects the methylation of DLG4 gene
[Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of DLG4 protein]
CTD PMID:27567873 PMID:30521419 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dlgap1 DLG associated protein 1 increases expression ISO Cannabidiol results in increased expression of DLGAP1 mRNA CTD PMID:33019509 NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817
JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions
increases expression
ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of DLL1 mRNA]
Cannabidiol results in increased expression of DLL1 mRNA
CTD PMID:30742662 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Dlx5 distal-less homeobox 5 increases expression ISO Cannabidiol results in increased expression of DLX5 protein CTD PMID:32656944 NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407
JBrowse link
G Dmd dystrophin multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG12 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG4B mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of BECN1 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ULK1 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of IL6 protein]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of IL6RA mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of NOS2 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TGFB1 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TNF mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TNF protein] CTD PMID:30074247 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO Cannabidiol results in increased expression of DNAJB1 mRNA CTD PMID:26504004 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions
increases expression
ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of DNAJB4 mRNA
Cannabidiol results in increased expression of DNAJB4 mRNA
CTD PMID:26504004 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 multiple interactions
increases expression
ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of DNAJB9 mRNA
Cannabidiol results in increased expression of DNAJB9 mRNA
CTD PMID:26504004 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnmt3l DNA methyltransferase 3 like increases expression ISO Cannabidiol results in increased expression of DNMT3L mRNA CTD PMID:21542829 NCBI chr20:10,614,933...10,629,516
Ensembl chr20:10,614,934...10,629,516
JBrowse link
G Dok2 docking protein 2 decreases expression ISO Cannabidiol results in decreased expression of DOK2 mRNA CTD PMID:21542829 NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402
JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO Cannabidiol results in decreased expression of DRD2 mRNA CTD PMID:33019509 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Cannabidiol results in increased expression of DUSP1 mRNA CTD PMID:21542829 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO [Cannabidiol co-treated with MOG protein modified form] results in increased expression of DUSP6 mRNA; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of DUSP6 mRNA] CTD PMID:27256343 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO Cannabidiol results in increased expression of E2F2 mRNA CTD PMID:30742662 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO Cannabidiol results in decreased expression of E2F5 mRNA CTD PMID:30742662 NCBI chr 2:86,997,331...87,012,901
Ensembl chr 2:86,997,332...87,012,990
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in decreased expression of EGFR mRNA; Pertussis Toxin inhibits the reaction [[Dronabinol co-treated with Cannabidiol] results in decreased expression of EGFR mRNA] CTD PMID:32049991 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of EGR1 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of EGR1 mRNA
CTD PMID:26504004 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 decreases expression ISO Cannabidiol results in decreased expression of EIF2AK3 mRNA CTD PMID:33019509 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO Cannabidiol results in increased expression of EIF4EBP1 mRNA CTD PMID:21542829 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression ISO Cannabidiol results in decreased expression of EIF5A mRNA CTD PMID:21542829 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Eno2 enolase 2 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of ENO2 mRNA] CTD PMID:17672854 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO Cannabidiol results in increased expression of EPHX1 mRNA CTD PMID:27256343 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression ISO Cannabidiol results in decreased expression of ERN1 mRNA CTD PMID:33019509 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO Cannabidiol results in increased expression of ETS2 mRNA CTD PMID:27256343 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Ezr ezrin affects methylation EXP Cannabidiol affects the methylation of EZR gene CTD PMID:30521419 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO Cannabidiol results in increased expression of F3 protein CTD PMID:27556861 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO Cannabidiol inhibits the reaction [11-(dansylamino)undecanoic acid binds to FABP1 protein] CTD PMID:31110286 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Cannabidiol results in increased expression of FAS mRNA CTD PMID:30742662 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxo32 F-box protein 32 multiple interactions
increases expression
ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of FBXO32 mRNA
Cannabidiol results in increased expression of FBXO32 mRNA
CTD PMID:26504004 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of FDPS mRNA] CTD PMID:27256343 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fgf12 fibroblast growth factor 12 affects methylation EXP Cannabidiol affects the methylation of FGF12 gene CTD PMID:30521419 NCBI chr11:71,997,049...72,564,965
Ensembl chr11:71,997,099...72,562,607
JBrowse link
G Fgf14 fibroblast growth factor 14 affects methylation EXP Cannabidiol affects the methylation of FGF14 gene CTD PMID:30521419 NCBI chr15:101,045,038...101,679,888
Ensembl chr15:101,045,036...101,679,900
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects methylation EXP Cannabidiol affects the methylation of FGFR2 gene CTD PMID:30521419 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 affects methylation EXP Cannabidiol affects the methylation of FGFR4 gene CTD PMID:30521419 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of FOS mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of FOS mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Cannabidiol results in increased expression of FOSB mRNA CTD PMID:26504004 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA] CTD PMID:31953017 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Fzd9 frizzled class receptor 9 affects methylation EXP Cannabidiol affects the methylation of FZD9 gene CTD PMID:30521419 NCBI chr12:21,427,084...21,429,398
Ensembl chr12:21,427,084...21,429,398
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GABRA1 protein] CTD PMID:27567873 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions EXP Cannabidiol inhibits the reaction [Poly I-C results in decreased expression of GAD1 protein] CTD PMID:31202911 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
multiple interactions
ISO Cannabidiol results in increased expression of GADD45A mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of GADD45A mRNA
CTD PMID:21542829 PMID:26504004 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of GAS1 mRNA
Cannabidiol results in increased expression of GAS1 mRNA
CTD PMID:30742662 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Cannabidiol results in increased expression of GCLM mRNA CTD PMID:21542829 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of GDF15 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of GDF15 mRNA
CTD PMID:21542829 PMID:26504004 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdf6 growth differentiation factor 6 affects methylation EXP Cannabidiol affects the methylation of GDF6 gene CTD PMID:30521419 NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567
JBrowse link
G Gfod1 glucose-fructose oxidoreductase domain containing 1 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GFOD1 mRNA] CTD PMID:27256343 NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938
JBrowse link
G Gli1 GLI family zinc finger 1 affects methylation EXP Cannabidiol affects the methylation of GLI1 gene CTD PMID:30521419 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Gnai2 G protein subunit alpha i2 increases expression ISO Cannabidiol results in increased expression of GNAI2 mRNA CTD PMID:33019509 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnal G protein subunit alpha L decreases expression ISO Cannabidiol results in decreased expression of GNAL mRNA CTD PMID:33019509 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
JBrowse link
G Gnb2 G protein subunit beta 2 affects methylation EXP Cannabidiol affects the methylation of GNB2 gene CTD PMID:30521419 NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
JBrowse link
G Gnb4 G protein subunit beta 4 increases expression ISO Cannabidiol results in increased expression of GNB4 mRNA CTD PMID:33019509 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
JBrowse link
G Gng7 G protein subunit gamma 7 affects methylation EXP Cannabidiol affects the methylation of GNG7 gene CTD PMID:30521419 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Cannabidiol results in increased expression of GPNMB mRNA CTD PMID:27256343 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr183 G protein-coupled receptor 183 decreases expression ISO Cannabidiol results in decreased expression of GPR183 mRNA CTD PMID:21542829 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559
JBrowse link
G Gpr83 G protein-coupled receptor 83 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of GPR83 mRNA] CTD PMID:27256343 NCBI chr 8:11,693,540...11,704,028
Ensembl chr 8:11,693,540...11,704,028
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Cannabidiol results in increased expression of GPT2 mRNA CTD PMID:21542829 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GRIA2 protein] CTD PMID:27567873 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO Cannabidiol results in decreased activity of GSR protein CTD PMID:18929579 PMID:32752303 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO Cannabidiol results in increased expression of GSTM1 mRNA CTD PMID:21542829 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Cannabidiol results in increased expression of H1F2 mRNA CTD PMID:21542829 NCBI chr17:41,391,106...41,392,611 JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression
ISO Cannabidiol promotes the reaction [Dronabinol results in increased expression of H2AX protein modified form]; Dronabinol promotes the reaction [Cannabidiol results in increased expression of H2AX protein modified form] CTD PMID:27769052 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hap1 huntingtin-associated protein 1 increases expression ISO Cannabidiol results in increased expression of HAP1 mRNA CTD PMID:33019509 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO Cannabidiol results in increased expression of HBP1 mRNA CTD PMID:30742662 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of HERPUD1 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of HERPUD1 mRNA
CTD PMID:21542829 PMID:26504004 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes2 hes family bHLH transcription factor 2 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of HES2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of HES2 mRNA
CTD PMID:30742662 NCBI chr 5:162,667,190...162,668,235
Ensembl chr 5:162,667,190...162,668,235
JBrowse link
G Hgf hepatocyte growth factor affects methylation EXP Cannabidiol affects the methylation of HGF gene CTD PMID:30521419 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F increases expression ISO Cannabidiol results in increased expression of H2AC6 mRNA CTD PMID:21542829 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 increases expression ISO Cannabidiol results in increased expression of H3C6 mRNA CTD PMID:21542829 NCBI chr17:41,568,666...41,569,076
Ensembl chr17:41,568,471...41,569,109
JBrowse link
G Hist2h2be histone cluster 2 H2B family member E increases expression ISO Cannabidiol results in increased expression of H2BC21 mRNA CTD PMID:21542829 NCBI chr 2:183,780,449...183,783,030 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
affects response to substance
ISO Cannabidiol results in increased expression of HMOX1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of HMOX1 mRNA; [Rotenone co-treated with Bilirubin] inhibits the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]; Rotenone promotes the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]
Cannabidiol results in increased expression of HMOX1 mRNA; Cannabidiol results in increased expression of HMOX1 protein
HMOX1 protein affects the susceptibility to Cannabidiol
[bafilomycin A1 co-treated with tin protoporphyrin IX] promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; [Dronabinol co-treated with Cannabidiol] results in increased expression of HMOX1 mRNA; Acetylcysteine inhibits the reaction [Cannabidiol results in increased expression of HMOX1 protein]; iodopravadoline promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Cannabidiol results in increased expression of HMOX1 protein]; tin protoporphyrin IX promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]
CTD PMID:21542829 PMID:26504004 PMID:30349652 PMID:30742662 PMID:32033040 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf1a HNF1 homeobox A affects methylation EXP Cannabidiol affects the methylation of HNF1A gene CTD PMID:30521419 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hp haptoglobin increases expression ISO Cannabidiol results in increased expression of HP mRNA CTD PMID:21542829 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Cannabidiol results in increased expression of HSPA1A mRNA CTD PMID:26504004
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression
multiple interactions
ISO Cannabidiol results in increased expression of HSPA1B mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of HSPA1B mRNA
CTD PMID:26504004 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Cannabidiol co-treated with Rotenone] results in increased expression of HSPA5 mRNA; Bilirubin inhibits the reaction [[Cannabidiol co-treated with Rotenone] results in increased expression of HSPA5 mRNA] CTD PMID:32033040 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Cannabidiol results in increased expression of HTATIP2 mRNA CTD PMID:21542829 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]; AM 251 inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]; capsazepine inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]; ICAM1 mutant form inhibits the reaction [Cannabidiol results in increased expression of TIMP1 protein]; iodopravadoline inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]
Cannabidiol results in increased expression of ICAM1 mRNA; Cannabidiol results in increased expression of ICAM1 protein
CTD PMID:22198381 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression
affects response to substance
ISO Cannabidiol results in decreased expression of ID1 mRNA; Cannabidiol results in decreased expression of ID1 protein
ID1 protein affects the susceptibility to Cannabidiol
CTD PMID:21542829 PMID:24910342 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO AM 281 promotes the reaction [Cannabidiol inhibits the reaction [Plant Preparations results in increased activity of IDO1 protein]]; Cannabidiol inhibits the reaction [[Plant Preparations results in increased activity of IDO1 protein] which results in increased abundance of Neopterin]; Cannabidiol inhibits the reaction [Plant Preparations results in increased activity of IDO1 protein]; Cannabidiol inhibits the reaction [Plant Preparations results in increased expression of IDO1 mRNA]; iodopravadoline promotes the reaction [Cannabidiol inhibits the reaction [Plant Preparations results in increased activity of IDO1 protein]] CTD PMID:19167098 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IER3 mRNA] CTD PMID:27256343 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of IFNB1 mRNA; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNB1 mRNA]; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IFNB1 protein]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
Cannabidiol results in increased expression of IFNB1 mRNA
CTD PMID:19910459 PMID:21542829 PMID:30742662 PMID:32244040 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Cannabidiol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [IFNG protein results in increased expression of PSMB8 protein]; Cannabidiol affects the reaction [Plant Preparations results in increased secretion of IFNG protein]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA]; Cannabidiol inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]; Cannabidiol inhibits the reaction [IFNG protein results in increased expression of PSMB8 protein]; Cannabidiol inhibits the reaction [Plant Preparations results in increased expression of IFNG mRNA]; Cannabidiol promotes the reaction [Dronabinol inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]]; Dronabinol promotes the reaction [Cannabidiol inhibits the reaction [IFNG results in increased expression of PSMB8 mRNA]] CTD PMID:19167098 PMID:27769052 PMID:31054246 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IFNGR1 mRNA] CTD PMID:27256343 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA] CTD PMID:31953017 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of IGFBP4 mRNA
Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IGFBP4 mRNA]
CTD PMID:21542829 PMID:27256343 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Il12a interleukin 12A multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL12A mRNA] CTD PMID:27256343 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO
EXP
Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL1B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL1B protein]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of IL1B protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
Cannabidiol results in decreased expression of IL1B mRNA
CTD PMID:19910459 PMID:21492165 PMID:21542829 PMID:27256343 PMID:27430346 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression ISO Cannabidiol results in increased expression of IL2 protein CTD PMID:11809870 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il3 interleukin 3 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL3 protein] CTD PMID:27256343 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of IL6 mRNA; [Rotenone co-treated with Bilirubin] inhibits the reaction [Cannabidiol results in increased expression of IL6 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of IL6 mRNA]; Cannabidiol inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of IL6 protein]; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]; Rotenone inhibits the reaction [Cannabidiol results in increased expression of IL6 mRNA]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD PMID:19910459 PMID:21350020 PMID:21492165 PMID:27430346 PMID:30074247 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of IL6RA mRNA
Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of IL6RA mRNA]
CTD PMID:30074247 PMID:30742662 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D decreases expression ISO Cannabidiol results in decreased expression of INPP5D mRNA CTD PMID:30742662 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of IRAK1 protein] CTD PMID:19910459 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of IRAK3 mRNA CTD PMID:30742662 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C affects the localization of IRF3 protein]; Cannabidiol inhibits the reaction [Poly I-C affects the localization of IRF3 protein] CTD PMID:32244040 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions
increases expression
ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of IRF4 mRNA]
Cannabidiol results in increased expression of IRF4 mRNA
CTD PMID:27256343 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
JBrowse link
G Itgb3 integrin subunit beta 3 affects methylation EXP Cannabidiol affects the methylation of ITGB3 gene CTD PMID:30521419 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jak3 Janus kinase 3 affects methylation EXP Cannabidiol affects the methylation of JAK3 gene CTD PMID:30521419 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Jaml junction adhesion molecule like multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of JAML mRNA] CTD PMID:27256343 NCBI chr 8:45,384,836...45,415,459
Ensembl chr 8:45,383,495...45,416,565
JBrowse link
G Jdp2 Jun dimerization protein 2 increases expression ISO Cannabidiol results in increased expression of JDP2 mRNA CTD PMID:21542829 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO Cannabidiol results in decreased expression of KCTD12 mRNA CTD PMID:21542829 NCBI chr15:79,800,077...79,806,064 JBrowse link
G Klf4 Kruppel like factor 4 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of KLF4 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of KLF4 mRNA
CTD PMID:26504004 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases expression EXP Cannabidiol results in decreased expression of KRAS mRNA CTD PMID:32553926 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lamc1 laminin subunit gamma 1 affects methylation EXP Cannabidiol affects the methylation of LAMC1 gene CTD PMID:30521419 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Cannabidiol results in increased expression of LCN2 mRNA CTD PMID:21542829 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Limk2 LIM domain kinase 2 affects methylation EXP Cannabidiol affects the methylation of LIMK2 gene CTD PMID:30521419 NCBI chr14:78,208,182...78,286,106
Ensembl chr14:78,218,063...78,286,007
JBrowse link
G Llgl1 LLGL scribble cell polarity complex component 1 affects methylation EXP Cannabidiol affects the methylation of LLGL1 gene CTD PMID:30521419 NCBI chr10:45,379,423...45,394,096
Ensembl chr10:45,379,515...45,394,094
JBrowse link
G LOC102553180 protocadherin alpha-1-like increases expression ISO Cannabidiol results in increased expression of PCDHA1 mRNA CTD PMID:21542829
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO Cannabidiol results in increased expression of HSPA6 mRNA CTD PMID:26504004 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Lpin1 lipin 1 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of LPIN1 mRNA
Cannabidiol results in increased expression of LPIN1 mRNA
CTD PMID:30742662 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Ly86 lymphocyte antigen 86 decreases expression ISO Cannabidiol results in decreased expression of LY86 mRNA CTD PMID:21542829 NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260
JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of MAFB mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of MAFB mRNA
CTD PMID:30742662 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 affects methylation EXP Cannabidiol affects the methylation of MAP2K1 gene CTD PMID:30521419 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 affects methylation EXP Cannabidiol affects the methylation of MAP2K6 gene CTD PMID:30521419 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Cannabidiol results in decreased expression of MAP3K5 mRNA CTD PMID:33019509 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
affects expression
ISO Cannabidiol results in increased phosphorylation of MAPK1 protein
tanespimycin affects the reaction [Cannabidiol affects the expression of MAPK1 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of MAPK1 protein]
CTD PMID:26504004 PMID:28601556 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 decreases expression EXP Cannabidiol results in decreased expression of MAPK14 mRNA CTD PMID:32553926 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
affects expression
ISO Cannabidiol results in increased phosphorylation of MAPK3 protein
tanespimycin affects the reaction [Cannabidiol affects the expression of MAPK3 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of MAPK3 protein]
CTD PMID:26504004 PMID:28601556 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapt microtubule-associated protein tau affects methylation EXP Cannabidiol affects the methylation of MAPT gene CTD PMID:30521419 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO Cannabidiol results in decreased expression of MAT2A mRNA CTD PMID:21542829 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MDM2 mRNA
Cannabidiol results in increased expression of MDM2 mRNA
CTD PMID:30742662 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mecom MDS1 and EVI1 complex locus affects methylation EXP Cannabidiol affects the methylation of MECOM gene CTD PMID:30521419 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression ISO Cannabidiol results in decreased expression of MEF2C mRNA CTD PMID:21542829 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mir145 microRNA 145 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR145A mRNA CTD PMID:30742662 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir146a microRNA 146a multiple interactions
decreases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR146 mRNA; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MIR146 mRNA]
Cannabidiol results in decreased expression of MIR146 mRNA
CTD PMID:30742662 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir155 microRNA 155 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MIR155 mRNA] CTD PMID:30742662 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir181b1 microRNA 181b-1 increases expression ISO Cannabidiol results in increased expression of MIR181B-1 mRNA CTD PMID:30742662 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797
JBrowse link
G Mir21 microRNA 21 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR21A mRNA CTD PMID:30742662 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir221 microRNA 221 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR221 mRNA CTD PMID:30742662 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir222 microRNA 222 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR222 mRNA CTD PMID:30742662 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mir25 microRNA 25 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of MIR25 mRNA CTD PMID:30742662 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015
JBrowse link
G Mir34a microRNA 34a multiple interactions
increases expression
ISO [Cannabidiol co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MIR34A mRNA
Cannabidiol results in increased expression of MIR34A mRNA
CTD PMID:30742662 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Mir449a microRNA 449a increases expression
multiple interactions
ISO Cannabidiol results in increased expression of MIR449A mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR449A mRNA
CTD PMID:30742662 NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804
JBrowse link
G Mitf melanocyte inducing transcription factor increases expression
multiple interactions
ISO Cannabidiol results in increased expression of MITF mRNA; Cannabidiol results in increased expression of MITF protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of MITF mRNA]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of MITF mRNA]
CTD PMID:28601556 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Cannabidiol results in decreased expression of MKI67 protein CTD PMID:24910342 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression ISO Cannabidiol results in increased expression of MMP23 mRNA CTD PMID:21542829 PMID:22178458 NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433
JBrowse link
G Mog myelin oligodendrocyte glycoprotein multiple interactions ISO [Cannabidiol co-treated with MOG protein modified form] results in increased expression of DUSP6 mRNA; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of ATF3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CDK5R1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CREM mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CSRNP1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCL9 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCR1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of DGAT1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of FDPS mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of GPR83 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IER3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IFNGR1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IGFBP4 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL12A mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL1B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of JAML mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of NR4A3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of SPHK1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF18 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF9 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF11 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF14 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TUBB2B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of VPS37B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of XCL1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL1B protein]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL3 protein]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of BTLA mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CD69 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CMPK2 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of DUSP6 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GBP11 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GFOD1 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of IRF4 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of MX2 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of PPIC mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of RSAD2 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TAGAP mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TNFSF8 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TRIM30A mRNA] CTD PMID:27256343 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
JBrowse link
G Mr1 major histocompatibility complex, class I-related multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of MR1 mRNA
Cannabidiol results in increased expression of MR1 mRNA
CTD PMID:30742662 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G Mt1 metallothionein 1 increases expression ISO Cannabidiol results in increased expression of MT1 mRNA CTD PMID:27256343 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A increases expression ISO Cannabidiol results in increased expression of MT2 mRNA CTD PMID:21542829 PMID:22178458 PMID:27256343 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mx1 MX dynamin like GTPase 1 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of MX2 mRNA] CTD PMID:27256343 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects methylation EXP Cannabidiol affects the methylation of MYC gene CTD PMID:30521419 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myh6 myosin heavy chain 6 increases expression ISO Cannabidiol results in increased expression of MYHC mRNA CTD PMID:30074247 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
JBrowse link
G Myog myogenin multiple interactions
increases expression
ISO iodoresiniferatoxin inhibits the reaction [Cannabidiol results in increased expression of MYOG mRNA] CTD PMID:30074247 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Nckap1l NCK associated protein 1 like affects methylation EXP Cannabidiol affects the methylation of NCKAP1L gene CTD PMID:30521419 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of NDRG1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of NDRG1 mRNA
CTD PMID:21542829 PMID:22178458 PMID:30742662 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 increases expression ISO Cannabidiol results in increased expression of NEURL1A mRNA CTD PMID:21542829 NCBI chr 1:246,066,642...246,152,890
Ensembl chr 1:246,067,100...246,152,903
JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 decreases expression ISO Cannabidiol results in decreased expression of NFAM1 mRNA CTD PMID:21542829 NCBI chr 7:114,139,318...114,175,395
Ensembl chr 7:114,139,345...114,175,442
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of NFATC2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of NFATC2 mRNA
CTD PMID:30742662 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 increases expression ISO Cannabidiol results in increased expression of NFE2L1 mRNA CTD PMID:21542829 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of NFE2L2 protein
NFE2L2 protein affects the reaction [Cannabidiol results in increased expression of HMOX1 protein]
CTD PMID:32708634 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO Cannabidiol results in increased expression of NFIL3 mRNA CTD PMID:26504004 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression ISO Cannabidiol results in increased expression of NFKB1 mRNA CTD PMID:21542829 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbib NFKB inhibitor beta increases expression ISO Cannabidiol results in increased expression of NFKBIB mRNA CTD PMID:21542829 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO
EXP
Cannabidiol results in increased expression of NOS2 mRNA
Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of NOS2 mRNA]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS2 protein]
CTD PMID:27430346 PMID:30074247 PMID:30742662 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Cannabidiol results in increased expression of NQO1 mRNA CTD PMID:21542829 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of NR4A3 mRNA] CTD PMID:27256343 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 affects methylation EXP Cannabidiol affects the methylation of NTRK2 gene CTD PMID:30521419 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Cannabidiol results in increased expression of NUPR1 mRNA CTD PMID:21542829 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions EXP Cannabidiol inhibits the reaction [naltrindole binds to and results in decreased activity of OPRD1 protein] CTD PMID:16489449 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions EXP Cannabidiol promotes the reaction [Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]] CTD PMID:16489449 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Cannabidiol results in increased cleavage of PARP1 protein CTD PMID:29441458 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 decreases expression ISO Cannabidiol results in decreased expression of PARP4 mRNA CTD PMID:33019509 NCBI chr15:30,690,503...30,792,868 JBrowse link
G Pax8 paired box 8 affects methylation EXP Cannabidiol affects the methylation of PAX8 gene CTD PMID:30521419 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Pcdha1 protocadherin alpha 1 increases expression ISO Cannabidiol results in increased expression of PCDHA1 mRNA CTD PMID:21542829
G Pcdha11 protocadherin alpha 11 increases expression ISO Cannabidiol results in increased expression of PCDHA11 mRNA CTD PMID:21542829
G Pdx1 pancreatic and duodenal homeobox 1 increases expression EXP Cannabidiol results in increased expression of PDX1 protein CTD PMID:32553926 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Penk proenkephalin multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of PENK mRNA] CTD PMID:17672854 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Pfn2 profilin 2 increases expression ISO Cannabidiol results in increased expression of PFN2 mRNA CTD PMID:21542829 NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938
JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma affects methylation EXP Cannabidiol affects the methylation of PIP5K1C gene CTD PMID:30521419 NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988
JBrowse link
G Pitpnm2 phosphatidylinositol transfer protein, membrane-associated 2 increases expression ISO Cannabidiol results in increased expression of PITPNM2 mRNA CTD PMID:27256343 NCBI chr12:32,347,455...32,479,103
Ensembl chr12:32,380,805...32,479,102
JBrowse link
G Pld1 phospholipase D1 decreases expression ISO Cannabidiol results in decreased expression of PLD1 mRNA CTD PMID:33019509 NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Plin2 perilipin 2 increases expression ISO Cannabidiol results in increased expression of PLIN2 mRNA CTD PMID:21542829 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO Cannabidiol results in increased expression of PLK2 mRNA CTD PMID:21542829 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression ISO Cannabidiol results in increased expression of PLPP3 mRNA CTD PMID:21542829 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Cannabidiol results in increased expression of PMAIP1 mRNA CTD PMID:26504004 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Polr1g RNA polymerase I subunit G decreases expression ISO Cannabidiol results in decreased expression of CD3EAP mRNA CTD PMID:21542829 NCBI chr 1:79,007,490...79,010,766
Ensembl chr 1:79,007,490...79,010,766
JBrowse link
G Pomgnt2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) decreases expression ISO Cannabidiol results in decreased expression of POMGNT2 mRNA CTD PMID:21542829 NCBI chr 8:121,645,106...121,660,761
Ensembl chr 8:121,644,970...121,660,757
JBrowse link
G Pou5f1 POU class 5 homeobox 1 affects methylation EXP Cannabidiol affects the methylation of POU5F1 gene CTD PMID:30521419 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects methylation EXP Cannabidiol affects the methylation of PPARD gene CTD PMID:30521419 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
decreases expression
multiple interactions
affects binding
ISO
EXP
Cannabidiol results in increased expression of PPARG mRNA
Cannabidiol results in decreased expression of PPARG protein
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of PPARG mRNA
Cannabidiol binds to PPARG protein
Cannabidiol results in increased expression of and affects the localization of PPARG protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Cannabidiol affects the localization of PPARG protein]
CTD PMID:19285060 PMID:23220503 PMID:28853159 PMID:30742662 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppic peptidylprolyl isomerase C multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of PPIC mRNA] CTD PMID:27256343 NCBI chr18:46,842,410...46,855,016
Ensembl chr18:46,842,409...46,855,017
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma affects methylation EXP Cannabidiol affects the methylation of PPP1CC gene CTD PMID:30521419 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression
multiple interactions
ISO Cannabidiol results in increased expression of PPP1R15A mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of PPP1R15A mRNA
CTD PMID:21542829 PMID:26504004 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C increases expression ISO Cannabidiol results in increased expression of PPP1R3C mRNA CTD PMID:26504004 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha decreases expression ISO Cannabidiol results in decreased expression of PPP3R1 mRNA CTD PMID:33019509 NCBI chr14:91,556,743...91,606,230
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha affects methylation EXP Cannabidiol affects the methylation of PRKACA gene CTD PMID:30521419 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkca protein kinase C, alpha increases expression ISO Cannabidiol results in increased expression of PRKCA mRNA CTD PMID:33019509 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcb protein kinase C, beta decreases expression ISO Cannabidiol results in decreased expression of PRKCB mRNA CTD PMID:33019509 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prl prolactin multiple interactions ISO Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein] CTD PMID:31154070 PMID:31953017 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions
increases expression
ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of PSAT1 mRNA
Cannabidiol results in increased expression of PSAT1 mRNA
CTD PMID:26504004 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GABRA1 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GRIA2 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of SNAP25 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of DLG4 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [APP gene mutant form co-treated with PSEN1 gene mutant form] CTD PMID:27567873 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [IFNG protein results in increased expression of PSMB8 protein]; Cannabidiol inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]; Cannabidiol inhibits the reaction [IFNG protein results in increased expression of PSMB8 protein]; Cannabidiol promotes the reaction [Dronabinol inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]]; Dronabinol promotes the reaction [Cannabidiol inhibits the reaction [IFNG results in increased expression of PSMB8 mRNA]] CTD PMID:27769052 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
JBrowse link
G Ptch1 patched 1 affects methylation EXP Cannabidiol affects the methylation of PTCH1 gene CTD PMID:30521419 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Ptgir prostaglandin I2 receptor increases expression ISO Cannabidiol results in increased expression of PTGIR mRNA CTD PMID:21542829 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO
EXP
Cannabidiol results in increased expression of PTGS2 mRNA; Cannabidiol results in increased expression of PTGS2 protein
[Dronabinol co-treated with Cannabidiol] results in increased expression of PTGS2 mRNA
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of PTGS2 mRNA]
CTD PMID:23220503 PMID:26504004 PMID:27430346 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptpn14 protein tyrosine phosphatase, non-receptor type 14 increases expression ISO Cannabidiol results in increased expression of PTPN14 mRNA CTD PMID:21542829 NCBI chr13:101,268,258...101,420,508
Ensembl chr13:101,268,416...101,414,088
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J decreases expression ISO Cannabidiol results in decreased expression of PTPRJ mRNA CTD PMID:30742662 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260
JBrowse link
G Pvalb parvalbumin multiple interactions
increases expression
EXP [Poly I-C co-treated with Cannabidiol] results in increased expression of PVALB protein
Cannabidiol results in increased expression of PVALB protein
CTD PMID:31202911 PMID:31326506 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
JBrowse link
G Rab3il1 RAB3A interacting protein-like 1 decreases expression ISO Cannabidiol results in decreased expression of RAB3IL1 mRNA CTD PMID:21542829 NCBI chr 1:206,646,168...206,682,718
Ensembl chr 1:206,646,155...206,679,972
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 affects methylation EXP Cannabidiol affects the methylation of RASGRP1 gene CTD PMID:30521419 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of RELA mRNA; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein] CTD PMID:19910459 PMID:30742662 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Cannabidiol results in increased expression of RELB mRNA CTD PMID:21542829 PMID:30742662 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Rin2 Ras and Rab interactor 2 decreases expression ISO Cannabidiol results in decreased expression of RIN2 mRNA CTD PMID:21542829 NCBI chr 3:133,086,858...133,303,604
Ensembl chr 3:133,086,749...133,303,604
JBrowse link
G Rnd3 Rho family GTPase 3 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of RND3 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of RND3 mRNA
CTD PMID:26504004 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Rora RAR-related orphan receptor A multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of RORA mRNA
Cannabidiol results in increased expression of RORA mRNA
CTD PMID:30742662 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Cannabidiol results in decreased phosphorylation of RPS6 protein CTD PMID:28392768 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of RSAD2 mRNA; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of RSAD2 mRNA]
Cannabidiol results in increased expression of RSAD2 mRNA
CTD PMID:27256343 PMID:30742662 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO Cannabidiol results in increased expression of RUNX2 protein CTD PMID:32656944 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 increases expression ISO Cannabidiol results in increased expression of S1PR1 mRNA CTD PMID:30742662 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO Cannabidiol results in increased expression of SARS mRNA CTD PMID:21542829 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Scin scinderin affects methylation EXP Cannabidiol affects the methylation of SCIN gene CTD PMID:30521419 NCBI chr 6:57,110,128...57,188,059
Ensembl chr 6:57,109,403...57,188,242
JBrowse link
G Serpine1 serpin family E member 1 decreases expression
increases response to substance
decreases secretion
multiple interactions
ISO Cannabidiol results in decreased expression of SERPINE1 mRNA
SERPINE1 protein results in increased susceptibility to Cannabidiol
Cannabidiol results in decreased secretion of SERPINE1 protein
CNR1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]; CNR2 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]; TRPV1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]
CTD PMID:20668920 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sesn2 sestrin 2 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of SESN2 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of SESN2 mRNA
CTD PMID:26504004 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sfxn4 sideroflexin 4 increases expression ISO Cannabidiol results in increased expression of SFXN4 mRNA CTD PMID:21542829 NCBI chr 1:259,976,480...259,998,778
Ensembl chr 1:259,976,481...259,998,754
JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 decreases expression ISO Cannabidiol results in decreased expression of SHANK1 mRNA CTD PMID:33019509 NCBI chr 1:94,807,879...94,857,356
Ensembl chr 1:94,808,276...94,855,824
JBrowse link
G Slc18a1 solute carrier family 18 member A1 decreases expression ISO Cannabidiol results in decreased expression of SLC18A1 mRNA CTD PMID:33019509 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051
JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases expression ISO Cannabidiol results in decreased expression of SLC1A2 mRNA CTD PMID:33019509 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO Cannabidiol results in increased expression of SLC1A4 mRNA CTD PMID:21542829 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc25a22 solute carrier family 25 member 22 decreases expression ISO Cannabidiol results in decreased expression of SLC25A22 mRNA CTD PMID:21542829 NCBI chr 1:196,528,471...196,536,398
Ensembl chr 1:196,528,472...196,536,331
JBrowse link
G Slc2a6 solute carrier family 2 member 6 increases expression ISO Cannabidiol results in increased expression of SLC2A6 mRNA CTD PMID:21542829 NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of SLC30A1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of SLC30A1 mRNA
CTD PMID:21542829 PMID:22178458 PMID:27256343 PMID:30742662 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc32a1 solute carrier family 32 member 1 increases expression ISO Cannabidiol results in increased expression of SLC32A1 mRNA CTD PMID:33019509 NCBI chr 3:147,267,373...147,271,842
Ensembl chr 3:147,267,373...147,271,844
JBrowse link
G Slc38a1 solute carrier family 38, member 1 decreases expression ISO Cannabidiol results in decreased expression of SLC38A1 mRNA CTD PMID:33019509 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
JBrowse link
G Slc39a10 solute carrier family 39 member 10 decreases expression ISO Cannabidiol results in decreased expression of SLC39A10 mRNA CTD PMID:21542829 PMID:22178458 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
JBrowse link
G Slc39a4 solute carrier family 39 member 4 increases expression ISO Cannabidiol results in increased expression of SLC39A4 mRNA CTD PMID:21542829 PMID:22178458 NCBI chr 7:108,333,380...108,337,553
Ensembl chr 7:108,333,381...108,337,553
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Cannabidiol results in increased expression of SLC3A2 mRNA CTD PMID:21542829 PMID:27256343 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression ISO Cannabidiol results in increased expression of SLC40A1 mRNA CTD PMID:21542829 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc5a6 solute carrier family 5 member 6 decreases expression ISO Cannabidiol results in decreased expression of SLC5A6 mRNA CTD PMID:21542829 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712
JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases expression ISO Cannabidiol results in increased expression of SLC6A9 mRNA CTD PMID:21542829 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of SLC7A11 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of SLC7A11 mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Snap25 synaptosome associated protein 25 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of SNAP25 protein] CTD PMID:27567873 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
JBrowse link
G Sned1 sushi, nidogen and EGF-like domains 1 increases expression ISO Cannabidiol results in increased expression of SNED1 mRNA CTD PMID:21542829 NCBI chr 9:93,774,087...93,834,003
Ensembl chr 9:93,774,119...93,830,694
JBrowse link
G Soat2 sterol O-acyltransferase 2 increases expression ISO Cannabidiol results in increased expression of SOAT2 mRNA CTD PMID:21542829 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915
JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression ISO Cannabidiol results in increased expression of SOCS1 mRNA CTD PMID:30742662 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SOCS3 mRNA] CTD PMID:19910459 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of SOD1 mRNA] CTD PMID:17672854 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of SOD2 mRNA] CTD PMID:17672854 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox4 SRY-box transcription factor 4 increases expression ISO Cannabidiol results in increased expression of SOX4 mRNA CTD PMID:21542829 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
G Sp7 Sp7 transcription factor increases expression ISO Cannabidiol results in increased expression of SP7 protein CTD PMID:32656944 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of SPHK1 mRNA] CTD PMID:27256343 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G Spic Spi-C transcription factor increases expression ISO Cannabidiol results in increased expression of SPIC mRNA CTD PMID:21542829 NCBI chr 7:23,069,815...23,077,573
Ensembl chr 7:23,069,821...23,077,548
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Cannabidiol results in increased expression of SPP1 protein CTD PMID:32656944 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Sqstm1 sequestosome 1 increases expression
decreases expression
multiple interactions
ISO Cannabidiol results in increased expression of SQSTM1 mRNA
Cannabidiol results in decreased expression of SQSTM1 protein
[Dronabinol co-treated with Cannabidiol] results in decreased expression of SQSTM1 protein; Dronabinol promotes the reaction [Cannabidiol results in decreased expression of SQSTM1 protein]
CTD PMID:21542829 PMID:27769052 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects methylation
increases expression
EXP
ISO
Cannabidiol affects the methylation of SRC gene
Cannabidiol results in increased expression of SRC mRNA
CTD PMID:30521419 PMID:30742662 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Cannabidiol results in increased expression of SRXN1 mRNA CTD PMID:21542829 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Cannabidiol results in decreased expression of ST6GALNAC4 mRNA CTD PMID:21542829 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Cannabidiol results in increased expression of STAT1 mRNA CTD PMID:30742662 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:19910459 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stx11 syntaxin 11 increases expression ISO Cannabidiol results in increased expression of STX11 mRNA CTD PMID:21542829 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of TAC1 mRNA] CTD PMID:17672854 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tagap T-cell activation RhoGTPase activating protein multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TAGAP mRNA] CTD PMID:27256343 NCBI chr 1:47,170,725...47,179,705
Ensembl chr 1:47,170,725...47,179,792
JBrowse link
G Tbx3 T-box transcription factor 3 affects methylation EXP Cannabidiol affects the methylation of TBX3 gene CTD PMID:30521419 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tcf7l1 transcription factor 7 like 1 affects methylation EXP Cannabidiol affects the methylation of TCF7L1 gene CTD PMID:30521419 NCBI chr 4:104,680,734...104,846,086
Ensembl chr 4:104,680,739...104,845,287
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]
Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TGFB1 mRNA]
CTD PMID:30074247 PMID:32049991 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb3 transforming growth factor, beta 3 affects methylation EXP Cannabidiol affects the methylation of TGFB3 gene CTD PMID:30521419 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 affects methylation EXP Cannabidiol affects the methylation of TGFBR2 gene CTD PMID:30521419 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of TGIF2 mRNA CTD PMID:30742662 NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of TIMP1 mRNA; Cannabidiol results in increased expression of TIMP1 protein
ICAM1 mutant form inhibits the reaction [Cannabidiol results in increased expression of TIMP1 protein]
CTD PMID:22198381 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Cannabidiol results in increased expression of TJP1 protein CTD PMID:32656944 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor decreases expression ISO Cannabidiol results in decreased expression of TLE1 mRNA CTD PMID:21542829 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of TNF mRNA; Cannabidiol analog inhibits the reaction [Peptidoglycan results in increased expression of TNF protein]; Cannabidiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TNF mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TNF protein]
[Cannabidiol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; Cannabidiol analog inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD PMID:21492165 PMID:30074247 PMID:30742662 PMID:30796934 PMID:31054246 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO Cannabidiol results in increased expression of TNFAIP2 mRNA CTD PMID:21542829 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF18 mRNA] CTD PMID:27256343 NCBI chr 5:166,618,461...166,622,353
Ensembl chr 5:166,618,969...166,622,353
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF9 mRNA] CTD PMID:27256343 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF11 mRNA] CTD PMID:27256343 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnfsf14 TNF superfamily member 14 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF14 mRNA] CTD PMID:27256343 NCBI chr 9:2,069,075...2,073,128
Ensembl chr 9:2,069,104...2,073,216
JBrowse link
G Tnfsf8 TNF superfamily member 8 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TNFSF8 mRNA] CTD PMID:27256343 NCBI chr 5:77,253,881...77,277,078
Ensembl chr 5:77,251,373...77,277,421
JBrowse link
G Tnnt1 troponin T1, slow skeletal type increases expression
multiple interactions
ISO Cannabidiol results in increased expression of TNNT1 mRNA
iodoresiniferatoxin inhibits the reaction [Cannabidiol results in increased expression of TNNT1 mRNA]
CTD PMID:30074247 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions
decreases activity
ISO Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Dithiothreitol inhibits the reaction [Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]]
Cannabidiol metabolite results in decreased activity of TOP2A protein
CTD PMID:29272108 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Top2b DNA topoisomerase II beta multiple interactions
decreases activity
ISO Cannabidiol metabolite inhibits the reaction [TOP2B protein results in increased hydrolysis of Adenosine Triphosphate]
Cannabidiol metabolite results in decreased activity of TOP2B protein
CTD PMID:29272108 NCBI chr15:9,051,661...9,111,220
Ensembl chr15:9,051,341...9,112,085
JBrowse link
G Tp53 tumor protein p53 decreases expression EXP Cannabidiol results in decreased expression of TP53 mRNA CTD PMID:32553926 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Cannabidiol results in increased expression of TRP53INP1 mRNA CTD PMID:30742662 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tpm3 tropomyosin 3 affects methylation EXP Cannabidiol affects the methylation of TPM3 gene CTD PMID:30521419 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013
JBrowse link
G Traf1 TNF receptor-associated factor 1 increases expression ISO Cannabidiol results in increased expression of TRAF1 mRNA CTD PMID:21542829 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
JBrowse link
G Traf3 Tnf receptor-associated factor 3 affects methylation EXP Cannabidiol affects the methylation of TRAF3 gene CTD PMID:30521419 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481
JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 increases expression ISO Cannabidiol results in increased expression of TRAT1 mRNA CTD PMID:27256343 NCBI chr11:52,035,750...52,077,805
Ensembl chr11:52,035,750...52,077,805
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of TRIB3 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of TRIB3 mRNA
CTD PMID:21542829 PMID:26504004 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
increases activity
EXP
ISO
Cannabidiol binds to and results in increased activity of TRPA1 protein
Cannabidiol results in increased activity of TRPA1 protein
CTD PMID:18550765 PMID:30074247 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
ISO [Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; Cannabidiol inhibits the reaction [Capsaicin binds to TRPV1 protein]; Cannabidiol inhibits the reaction [resiniferatoxin binds to TRPV1 protein]; capsazepine inhibits the reaction [[Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; capsazepine inhibits the reaction [Cannabidiol results in increased activity of TRPV1 protein]; TRPV1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein] CTD PMID:11606325 PMID:20668920 PMID:30074247 PMID:31054246 PMID:31096838 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 increases activity
multiple interactions
ISO
EXP
Cannabidiol results in increased activity of TRPV2 protein
[Cannabidiol results in increased activity of TRPV2 protein] which results in increased uptake of Calcium
Cannabidiol analog binds to and results in increased activity of TRPV2 protein; Cannabidiol binds to and results in increased activity of TRPV2 protein
CTD PMID:18550765 PMID:31096838 NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of TSC22D3 mRNA CTD PMID:26504004 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tubb2b tubulin, beta 2B class IIb multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TUBB2B mRNA] CTD PMID:27256343 NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
JBrowse link
G Tyr tyrosinase multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased activity of TYR protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of TYR mRNA]; Cannabidiol results in increased expression of and results in increased activity of TYR protein; SB 203580 inhibits the reaction [Cannabidiol results in increased activity of TYR protein]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of TYR mRNA] CTD PMID:28601556 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of TYRP1 mRNA]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of TYRP1 mRNA]
Cannabidiol results in increased expression of TYRP1 mRNA; Cannabidiol results in increased expression of TYRP1 protein
CTD PMID:28601556 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ULK1 mRNA] CTD PMID:30074247 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression ISO Cannabidiol results in decreased expression of USP2 mRNA CTD PMID:21542829 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions
ISO Cannabidiol results in increased expression of VEGFA mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of VEGFA mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfb vascular endothelial growth factor B affects methylation EXP Cannabidiol affects the methylation of VEGFB gene CTD PMID:30521419 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
JBrowse link
G Vim vimentin multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA] CTD PMID:32049991 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vps37b VPS37B subunit of ESCRT-I multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of VPS37B mRNA] CTD PMID:27256343 NCBI chr12:32,560,047...32,589,015
Ensembl chr12:32,560,047...32,589,014
JBrowse link
G Vwf von Willebrand factor increases expression ISO Cannabidiol results in increased expression of VWF mRNA CTD PMID:21542829 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wasf2 WASP family member 2 affects methylation EXP Cannabidiol affects the methylation of WASF2 gene CTD PMID:30521419 NCBI chr 5:145,336,816...145,402,041
Ensembl chr 5:145,336,842...145,399,242
JBrowse link
G Wnt1 Wnt family member 1 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of WNT1 mRNA CTD PMID:30742662 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt11 Wnt family member 11 affects methylation EXP Cannabidiol affects the methylation of WNT11 gene CTD PMID:30521419 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294
JBrowse link
G Wnt7b Wnt family member 7B affects methylation EXP Cannabidiol affects the methylation of WNT7B gene CTD PMID:30521419 NCBI chr 7:116,634,817...116,679,089
Ensembl chr 7:116,634,814...116,679,581
JBrowse link
G Xbp1 X-box binding protein 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of XBP1 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of XBP1 mRNA
CTD PMID:26504004 PMID:32033040 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of XCL1 mRNA] CTD PMID:27256343 NCBI chr13:77,248,865...77,252,308
Ensembl chr13:77,248,717...77,252,329
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        biochemical role 19381
          metabolite 19356
            phytocannabinoid 423
              cannabidiol 418
                hydroxy-cannabidiol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic molecule 19560
                              organic cyclic compound 19351
                                organic aromatic compound 19176
                                  phenols 18146
                                    benzenediols 6096
                                      resorcinols 3813
                                        cannabidiol 418
                                          hydroxy-cannabidiol + 0
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