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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:casticin
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Accession:CHEBI:69355 term browser browse the term
Definition:A tetramethoxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6, 7 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii.
Synonyms:exact_synonym: 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-chromen-4-one
 related_synonym: 3',5-dihydroxy-3,4',6,7-tetramethoxyflavone;   3,6,7,4'-tetra-O-methyl-5,3'-dihydroxyflavone;   5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one;   Formula=C19H18O8;   InChI=1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3;   InChIKey=PJQLSMYMOKWUJG-UHFFFAOYSA-N;   SMILES=COc1ccc(cc1O)-c1oc2cc(OC)c(OC)c(O)c2c(=O)c1OC;   quercetagetin 3,6,7,4'-tetramethyl ether;   vitexicarpin
 xref: CAS:479-91-4;   HMDB:HMDB0030660;   LIPID_MAPS_instance:LMPK12113010
 xref_mesh: MESH:C054133
 xref: PMID:21877688;   PMID:22407499;   PMID:23135489;   PMID:23464460;   PMID:23476684;   PMID:23761826;   PMID:23816816;   PMID:24126491;   PMID:24247269;   Patent:CN101028261;   Patent:CN102743373;   Reaxys:1300392;   Wikipedia:Casticin


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casticin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO casticin results in increased expression of ABCC5 mRNA CTD PMID:28444820 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Adam10 ADAM metallopeptidase domain 10 increases expression ISO casticin results in increased expression of ADAM10 mRNA CTD PMID:28444820 NCBI chr 8:77,107,355...77,237,483
Ensembl chr 8:77,107,536...77,237,483
JBrowse link
G Aftph aftiphilin decreases expression ISO casticin results in decreased expression of AFTPH mRNA CTD PMID:28444820 NCBI chr14:104,921,633...104,975,763
Ensembl chr14:104,922,282...104,960,141
JBrowse link
G Agap1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 decreases expression ISO casticin results in decreased expression of AGAP1 mRNA CTD PMID:28444820 NCBI chr 9:96,718,901...97,034,400
Ensembl chr 9:96,621,586...97,030,163
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO casticin results in increased expression of AIFM1 protein CTD PMID:29098808 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akirin2 akirin 2 decreases expression ISO casticin results in decreased expression of AKIRIN2 mRNA CTD PMID:28444820 NCBI chr 5:50,001,945...50,016,544
Ensembl chr 5:50,002,184...50,016,539
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO casticin results in decreased expression of AKT1 protein CTD PMID:28444820 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt3 AKT serine/threonine kinase 3 decreases expression ISO casticin results in decreased expression of AKT3 mRNA CTD PMID:27862857 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO casticin results in increased expression of ALDH1A1 mRNA CTD PMID:27862857 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alx1 ALX homeobox 1 decreases expression ISO casticin results in decreased expression of ALX1 mRNA CTD PMID:28444820 NCBI chr 7:44,751,865...44,771,458
Ensembl chr 7:44,751,873...44,771,458
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO casticin results in increased expression of APAF1 protein CTD PMID:27862857 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 decreases expression ISO casticin results in decreased expression of ARL6IP4 mRNA CTD PMID:28444820 NCBI chr12:37,904,376...37,906,521
Ensembl chr12:37,904,379...37,906,521
JBrowse link
G Armc9 armadillo repeat containing 9 decreases expression ISO casticin results in decreased expression of ARMC9 mRNA CTD PMID:28444820 NCBI chr 9:93,172,718...93,299,119
Ensembl chr 9:93,172,673...93,296,750
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO casticin results in decreased expression of ARNTL mRNA CTD PMID:28444820 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Arpc5l actin related protein 2/3 complex, subunit 5-like decreases expression ISO casticin results in decreased expression of ARPC5L mRNA CTD PMID:28444820 NCBI chr 3:23,301,455...23,309,077
Ensembl chr 3:23,301,455...23,309,072
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO casticin results in decreased expression of ASNS mRNA CTD PMID:28444820 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO casticin results in decreased expression of ATF5 mRNA CTD PMID:28444820 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO casticin results in increased expression of ATF6 protein CTD PMID:27862857 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO casticin results in decreased expression of ATM protein CTD PMID:29098808 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atox1 antioxidant 1 copper chaperone increases expression ISO casticin results in increased expression of ATOX1 mRNA CTD PMID:28444820 NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 decreases expression ISO casticin results in decreased expression of ATP6V1G1 mRNA CTD PMID:28444820 NCBI chr 5:79,367,663...79,373,843
Ensembl chr 5:79,367,663...79,373,843
JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 increases expression ISO casticin results in increased expression of ATP8A1 mRNA CTD PMID:28444820 NCBI chr14:41,972,398...42,210,555
Ensembl chr14:42,015,347...42,206,311
JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO casticin results in decreased expression of ATR protein CTD PMID:29098808 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Atxn7l3b ataxin 7-like 3B decreases expression ISO casticin results in decreased expression of ATXN7L3B mRNA CTD PMID:28444820 NCBI chr 7:55,600,879...55,604,403
Ensembl chr 7:55,600,889...55,604,403
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression ISO casticin results in decreased expression of AVPR1A mRNA CTD PMID:28444820 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Axin2 axin 2 increases expression ISO casticin results in increased expression of AXIN2 mRNA CTD PMID:27862857 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO casticin results in increased expression of BAK1 protein CTD PMID:27862857 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO casticin results in increased expression of BAMBI mRNA CTD PMID:27862857 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO casticin results in decreased expression of BASP1 mRNA CTD PMID:28444820 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO casticin results in increased expression of BAX protein CTD PMID:27862857, PMID:29098808 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A decreases expression ISO casticin results in decreased expression of BCL11A mRNA CTD PMID:28444820 NCBI chr14:108,826,717...108,921,197
Ensembl chr14:108,826,831...108,921,669
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO casticin results in decreased expression of BCL2 protein CTD PMID:27862857, PMID:29098808 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
increases expression
ISO casticin results in decreased expression of BCL2L1 protein
casticin results in increased expression of BCL2L1 mRNA
CTD PMID:27862857, PMID:29098808 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist increases expression
decreases expression
ISO casticin results in increased expression of BID protein
casticin results in decreased expression of BID protein
CTD PMID:27862857, PMID:29098808 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger multiple interactions
decreases expression
ISO casticin promotes the reaction [MIR148A mRNA results in decreased expression of BMI1 mRNA]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of BMI1 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of BMI1 mRNA] CTD PMID:32268151 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO casticin results in increased expression of BMP4 mRNA CTD PMID:27862857 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bnip2 BCL2 interacting protein 2 decreases expression ISO casticin results in decreased expression of BNIP2 mRNA CTD PMID:27862857 NCBI chr 8:76,400,333...76,426,307
Ensembl chr 8:76,400,341...76,426,503
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO casticin results in increased expression of BRCA1 protein CTD PMID:29098808 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Btf3 basic transcription factor 3 decreases expression ISO casticin results in decreased expression of BTF3 mRNA CTD PMID:28444820 NCBI chr 2:28,417,316...28,424,436
Ensembl chr 2:28,417,579...28,423,762
JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression ISO casticin results in decreased expression of BTG1 mRNA CTD PMID:28444820 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression ISO casticin results in increased expression of CADM1 mRNA CTD PMID:28444820 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Calcoco1 calcium binding and coiled coil domain 1 decreases expression ISO casticin results in decreased expression of CALCOCO1 mRNA CTD PMID:28444820 NCBI chr 7:144,307,562...144,322,253
Ensembl chr 7:144,307,509...144,322,240
JBrowse link
G Calm1 calmodulin 1 decreases expression ISO casticin results in decreased expression of CALM1 mRNA CTD PMID:28444820 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression ISO casticin results in decreased expression of CAMK4 mRNA CTD PMID:27862857 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Capn1 calpain 1 multiple interactions ISO casticin results in increased expression of and results in increased cleavage of CAPN1 protein CTD PMID:27862857 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Capn2 calpain 2 increases expression ISO casticin results in increased expression of CAPN2 protein CTD PMID:27862857 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Casp2 caspase 2 increases expression ISO casticin results in increased expression of CASP2 protein CTD PMID:27862857 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO casticin results in increased cleavage of and results in increased activity of CASP3 protein
casticin results in increased activity of CASP3 protein
CTD PMID:27862857, PMID:29098808 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 increases expression ISO casticin results in increased expression of CASP4 protein CTD PMID:27862857 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp6 caspase 6 increases expression ISO casticin results in increased expression of CASP6 protein CTD PMID:27862857 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 increases expression ISO casticin results in increased expression of CASP7 protein CTD PMID:27862857 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions ISO casticin results in increased cleavage of and results in increased activity of CASP8 protein; casticin results in increased expression of and results in increased activity of CASP8 protein CTD PMID:27862857, PMID:29098808 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO casticin results in increased cleavage of and results in increased activity of CASP9 protein
casticin results in increased activity of CASP9 protein
CTD PMID:27862857, PMID:29098808 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccdc122 coiled-coil domain containing 122 increases expression ISO casticin results in increased expression of CCDC122 mRNA CTD PMID:28444820 NCBI chr15:59,159,822...59,280,538
Ensembl chr15:59,216,705...59,279,967
JBrowse link
G Ccdc174 coiled-coil domain containing 174 decreases expression ISO casticin results in decreased expression of CCDC174 mRNA CTD PMID:28444820 NCBI chr 4:123,760,708...123,787,529
Ensembl chr 4:123,760,743...123,787,528
JBrowse link
G Ccdc90b coiled-coil domain containing 90B decreases expression ISO casticin results in decreased expression of CCDC90B mRNA CTD PMID:28444820 NCBI chr 1:157,403,595...157,417,153
Ensembl chr 1:157,403,595...157,417,147
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO casticin results in increased expression of CCN1 mRNA CTD PMID:28444820 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO casticin results in decreased expression of CCNB1 protein CTD PMID:29098808 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 decreases expression ISO casticin results in decreased expression of CCT4 mRNA CTD PMID:28444820 NCBI chr14:107,767,392...107,780,270
Ensembl chr14:107,767,392...107,780,270
JBrowse link
G Cd24 CD24 molecule increases expression ISO casticin results in increased expression of CD24 mRNA CTD PMID:27862857 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression
multiple interactions
ISO casticin results in decreased expression of CD44 mRNA; casticin results in decreased expression of CD44 protein
casticin affects the reaction [MIR148A mRNA affects the expression of CD44 mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of CD44 protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of CD44 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of CD44 protein]
CTD PMID:32268151 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd83 CD83 molecule decreases expression ISO casticin results in decreased expression of CD83 mRNA CTD PMID:27862857 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO casticin results in decreased expression of CDC25C protein CTD PMID:29098808 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc42 cell division cycle 42 decreases expression ISO casticin results in decreased expression of CDC42 mRNA CTD PMID:28444820 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdh17 cadherin 17 increases expression ISO casticin results in increased expression of CDH17 mRNA CTD PMID:27862857 NCBI chr 5:25,354,187...25,443,675
Ensembl chr 5:25,391,115...25,443,718
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression ISO casticin results in increased expression of CDK2 protein CTD PMID:29098808 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO casticin results in decreased expression of CDKN1A mRNA; casticin results in decreased expression of CDKN1A protein CTD PMID:27862857, PMID:29098808 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO casticin results in increased expression of CDKN1B mRNA CTD PMID:27862857 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO casticin results in increased expression of CDKN2A protein CTD PMID:29098808 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO casticin results in increased expression of CHEK2 protein CTD PMID:29098808 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chic2 cysteine-rich hydrophobic domain 2 decreases expression ISO casticin results in decreased expression of CHIC2 mRNA CTD PMID:28444820 NCBI chr14:35,683,657...35,718,005
Ensembl chr14:35,683,442...35,717,922
JBrowse link
G Cldn1 claudin 1 decreases expression ISO casticin results in decreased expression of CLDN1 mRNA CTD PMID:27862857 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression ISO casticin results in decreased expression of CNBP mRNA CTD PMID:28444820 NCBI chr 4:119,747,890...119,756,787
Ensembl chr 4:119,747,911...119,756,765
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO casticin results in decreased expression of COL1A1 mRNA CTD PMID:27862857 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Cpe carboxypeptidase E increases expression ISO casticin results in increased expression of CPE mRNA CTD PMID:28444820 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO casticin results in increased expression of CREB1 mRNA CTD PMID:27862857 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression ISO casticin results in decreased expression of CRHBP mRNA CTD PMID:28444820 NCBI chr 2:25,141,471...25,153,334
Ensembl chr 2:25,141,471...25,153,334
JBrowse link
G Crls1 cardiolipin synthase 1 decreases expression ISO casticin results in decreased expression of CRLS1 mRNA CTD PMID:28444820 NCBI chr 3:125,503,638...125,522,460
Ensembl chr 3:125,503,638...125,522,441
JBrowse link
G Cryab crystallin, alpha B increases expression ISO casticin results in increased expression of CRYAB mRNA CTD PMID:28444820 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 decreases expression ISO casticin results in decreased expression of CSNK1A1 mRNA CTD PMID:28444820 NCBI chr18:56,887,722...56,910,610
Ensembl chr18:56,887,354...56,918,345
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 decreases expression ISO casticin results in decreased expression of CYB5R1 mRNA CTD PMID:28444820 NCBI chr13:51,229,697...51,236,447
Ensembl chr13:51,229,890...51,236,463
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO casticin results in increased expression of CYCS protein CTD PMID:27862857, PMID:29098808 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO casticin results in decreased expression of DDIT3 mRNA CTD PMID:28444820 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddx27 DEAD-box helicase 27 decreases expression ISO casticin results in decreased expression of DDX27 mRNA CTD PMID:28444820 NCBI chr 3:163,767,236...163,786,408
Ensembl chr 3:163,767,173...163,786,445
JBrowse link
G Dip2c disco-interacting protein 2 homolog C decreases expression ISO casticin results in decreased expression of DIP2C mRNA CTD PMID:28444820 NCBI chr17:63,426,688...63,810,183
Ensembl chr17:63,635,086...63,808,464
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 decreases expression ISO casticin results in decreased expression of DKK3 mRNA CTD PMID:27862857 NCBI chr 1:176,940,424...176,983,076
Ensembl chr 1:176,940,693...176,983,045
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases activity
decreases expression
ISO casticin affects the reaction [MIR148A mRNA affects the activity of DNMT1 protein]; casticin affects the reaction [MIR148A mRNA affects the expression of DNMT1 mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased activity of DNMT1 protein]; casticin results in decreased expression of and results in decreased activity of DNMT1 protein; DNMT1 protein inhibits the reaction [casticin results in decreased activity of DNMT1 protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of BMI1 protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of CD44 protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of EPCAM protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of NANOG protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of POU5F1 protein]; DNMT1 protein inhibits the reaction [casticin results in increased expression of MIR148A mRNA]; MIR148A mRNA affects the reaction [casticin results in decreased activity of DNMT1 protein]; MIR148A mRNA affects the reaction [casticin results in decreased expression of DNMT1 mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased activity of DNMT1 protein] CTD PMID:32268151 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression ISO casticin results in decreased expression of DUSP6 mRNA CTD PMID:28444820 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A decreases expression ISO casticin results in decreased expression of DYRK1A mRNA CTD PMID:28444820 NCBI chr11:34,858,339...34,958,733
Ensembl chr11:34,865,532...34,956,536
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO casticin results in decreased expression of EGFR protein CTD PMID:28444820 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta decreases expression ISO casticin results in decreased expression of EIF2S2 mRNA CTD PMID:28444820 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 decreases expression ISO casticin results in decreased expression of EIF5 mRNA CTD PMID:28444820 NCBI chr 6:136,002,983...136,011,409
Ensembl chr 6:136,004,214...136,011,406
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO casticin results in increased expression of ENC1 mRNA CTD PMID:27862857 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Endog endonuclease G decreases expression ISO casticin results in decreased expression of ENDOG protein CTD PMID:29098808 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Ep300 E1A binding protein p300 decreases expression ISO casticin results in decreased expression of EP300 mRNA CTD PMID:27862857 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epb41l4b erythrocyte membrane protein band 4.1 like 4B decreases expression ISO casticin results in decreased expression of EPB41L4B mRNA CTD PMID:28444820 NCBI chr 5:74,030,950...74,192,275
Ensembl chr 5:74,030,882...74,191,167
JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions
decreases expression
ISO casticin promotes the reaction [MIR148A mRNA results in decreased expression of EPCAM mRNA]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of EPCAM protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of EPCAM mRNA] CTD PMID:32268151 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 increases expression ISO casticin results in increased expression of ERBB3 mRNA CTD PMID:27862857 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Esf1 ESF1 nucleolar pre-rRNA processing protein homolog decreases expression ISO casticin results in decreased expression of ESF1 mRNA CTD PMID:28444820 NCBI chr 3:133,178,591...133,232,358
Ensembl chr 3:133,178,561...133,232,322
JBrowse link
G Exosc3 exosome component 3 decreases expression ISO casticin results in decreased expression of EXOSC3 mRNA CTD PMID:28444820 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Ext1 exostosin glycosyltransferase 1 increases expression ISO casticin results in increased expression of EXT1 mRNA CTD PMID:28444820 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
JBrowse link
G Fadd Fas associated via death domain increases expression ISO casticin results in increased expression of FADD protein CTD PMID:27862857, PMID:29098808 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fam227a family with sequence similarity 227, member A increases expression ISO casticin results in increased expression of FAM227A mRNA CTD PMID:28444820 NCBI chr 7:120,846,166...120,891,738
Ensembl chr 7:120,846,330...120,882,392
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO casticin results in increased expression of FAS protein CTD PMID:27862857, PMID:29098808 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression
decreases expression
ISO casticin results in increased expression of FASLG protein
casticin results in decreased expression of FASLG protein
CTD PMID:27862857, PMID:29098808 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbxo11 F-box protein 11 decreases expression ISO casticin results in decreased expression of FBXO11 mRNA CTD PMID:28444820 NCBI chr 6:11,662,356...11,737,427
Ensembl chr 6:11,662,356...11,686,682
JBrowse link
G Fbxo44 F-box protein 44 decreases expression ISO casticin results in decreased expression of FBXO44 mRNA CTD PMID:28444820 NCBI chr 5:164,962,921...164,972,273
Ensembl chr 5:164,963,433...164,971,903
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 decreases expression ISO casticin results in decreased expression of FEZ1 mRNA CTD PMID:28444820 NCBI chr 8:39,305,128...39,350,270
Ensembl chr 8:39,305,128...39,350,270
JBrowse link
G Foxo3 forkhead box O3 decreases expression ISO casticin results in decreased expression of FOXO3 mRNA CTD PMID:27862857 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Foxp2 forkhead box P2 decreases expression ISO casticin results in decreased expression of FOXP2 mRNA CTD PMID:28444820 NCBI chr 4:41,364,441...41,944,685
Ensembl chr 4:41,364,441...41,942,023
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO casticin results in decreased expression of GADD45A mRNA CTD PMID:28444820 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression ISO casticin results in decreased expression of GLUD1 mRNA CTD PMID:28444820 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Gphn gephyrin decreases expression ISO casticin results in decreased expression of GPHN mRNA CTD PMID:28444820 NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164
JBrowse link
G Gpr85 G protein-coupled receptor 85 decreases expression ISO casticin results in decreased expression of GPR85 mRNA CTD PMID:28444820 NCBI chr 4:40,377,705...40,387,147
Ensembl chr 4:40,381,685...40,385,349
JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO casticin results in decreased expression of GRB2 protein CTD PMID:28444820 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 decreases expression ISO casticin results in decreased expression of GRID2 mRNA CTD PMID:27862857 NCBI chr 4:94,068,112...95,476,864
Ensembl chr 4:94,696,965...95,442,778
JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 decreases expression ISO casticin results in decreased expression of GTF2H2 mRNA CTD PMID:28444820 NCBI chr 2:30,494,718...30,522,716
Ensembl chr 2:30,494,825...30,522,727
JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 decreases expression ISO casticin results in decreased expression of HCN2 mRNA CTD PMID:27862857 NCBI chr 7:12,851,730...12,870,087
Ensembl chr 7:12,851,739...12,874,215
JBrowse link
G Hoxb8 homeo box B8 decreases expression ISO casticin results in decreased expression of HOXB8 mRNA CTD PMID:28444820 NCBI chr10:84,131,484...84,133,874
Ensembl chr10:84,131,495...84,133,246
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO casticin results in decreased expression of HOXB9 mRNA CTD PMID:27862857 NCBI chr10:84,119,772...84,124,963
Ensembl chr10:84,119,884...84,123,390
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression ISO casticin results in decreased expression of HSPA4 mRNA CTD PMID:28444820 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO casticin results in increased expression of HSPA5 protein CTD PMID:27862857 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO casticin results in increased expression of HSPA8 mRNA CTD PMID:28444820 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO casticin results in decreased expression of HSPA9 mRNA CTD PMID:28444820 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Il12a interleukin 12A decreases expression ISO casticin results in decreased expression of IL12A mRNA CTD PMID:27862857 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il6 interleukin 6 decreases expression ISO casticin results in decreased expression of IL6 mRNA CTD PMID:27862857 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ints6 integrator complex subunit 6 decreases expression ISO casticin results in decreased expression of INTS6 mRNA CTD PMID:28444820 NCBI chr15:45,844,050...45,929,996
Ensembl chr15:45,858,608...45,947,030
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 increases expression ISO casticin results in increased expression of IRAK4 mRNA CTD PMID:27862857 NCBI chr 7:135,803,723...135,831,006
Ensembl chr 7:135,803,698...135,832,652
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression ISO casticin results in decreased expression of IRF2BP2 mRNA CTD PMID:28444820 NCBI chr19:59,497,021...59,502,298
Ensembl chr19:59,499,876...59,502,161
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases expression ISO casticin results in decreased expression of KCNH2 mRNA CTD PMID:28444820 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 decreases expression ISO casticin results in decreased expression of KCTD9 mRNA CTD PMID:28444820 NCBI chr15:44,411,591...44,439,645
Ensembl chr15:44,411,865...44,439,236
JBrowse link
G Kirrel3 kirre like nephrin family adhesion molecule 3 decreases expression ISO casticin results in decreased expression of KIRREL3 mRNA CTD PMID:28444820 NCBI chr 8:35,692,525...36,254,755
Ensembl chr 8:36,125,999...36,254,753
JBrowse link
G Klf9 Kruppel-like factor 9 decreases expression ISO casticin results in decreased expression of KLF9 mRNA CTD PMID:28444820 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Krt16 keratin 16 increases expression ISO casticin results in increased expression of KRT16 mRNA CTD PMID:28444820 NCBI chr10:88,149,210...88,152,167
Ensembl chr10:88,149,345...88,152,064
JBrowse link
G Ldhb lactate dehydrogenase B decreases expression ISO casticin results in decreased expression of LDHB mRNA CTD PMID:27862857 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 decreases expression ISO casticin results in decreased expression of LEF1 mRNA CTD PMID:27862857 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 increases expression ISO casticin results in increased expression of LHFP mRNA CTD PMID:28444820 NCBI chr 2:142,262,236...142,461,980
Ensembl chr 2:142,262,236...142,461,980
JBrowse link
G Limch1 LIM and calponin homology domains 1 increases expression ISO casticin results in increased expression of LIMCH1 mRNA CTD PMID:28444820 NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843
JBrowse link
G LOC102553180 protocadherin alpha-1-like increases expression ISO casticin results in increased expression of PCDHA1 mRNA CTD PMID:28444820 NCBI chr18:29,824,891...29,839,850 JBrowse link
G Lpl lipoprotein lipase decreases expression ISO casticin results in decreased expression of LPL mRNA CTD PMID:27862857 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp5 LDL receptor related protein 5 increases expression ISO casticin results in increased expression of LRP5 mRNA CTD PMID:27862857 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Ltv1 LTV1 ribosome biogenesis factor decreases expression ISO casticin results in decreased expression of LTV1 mRNA CTD PMID:28444820 NCBI chr 1:7,323,043...7,335,766
Ensembl chr 1:7,323,040...7,335,936
JBrowse link
G Maf MAF bZIP transcription factor decreases expression ISO casticin results in decreased expression of MAF mRNA CTD PMID:28444820 NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748
JBrowse link
G Magoh mago homolog, exon junction complex subunit decreases expression ISO casticin results in decreased expression of MAGOH mRNA CTD PMID:28444820 NCBI chr 5:127,480,465...127,487,617
Ensembl chr 5:127,480,485...127,487,603
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 increases expression ISO casticin results in increased expression of MAP3K7 mRNA CTD PMID:27862857 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 increases expression ISO casticin results in increased expression of MAPRE2 mRNA CTD PMID:28444820 NCBI chr18:14,814,149...15,780,290 JBrowse link
G Mark3 microtubule affinity regulating kinase 3 decreases expression ISO casticin results in decreased expression of MARK3 mRNA CTD PMID:28444820 NCBI chr 6:136,040,957...136,129,780
Ensembl chr 6:136,041,777...136,129,661
JBrowse link
G Max MYC associated factor X decreases expression ISO casticin results in decreased expression of MAX mRNA CTD PMID:28444820 NCBI chr 6:99,984,260...100,011,460
Ensembl chr 6:99,984,260...100,011,388
JBrowse link
G Mbp myelin basic protein increases expression ISO casticin results in increased expression of MBP mRNA CTD PMID:28444820 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO casticin results in decreased expression of MCL1 protein CTD PMID:27862857 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 increases expression ISO casticin results in increased expression of MDC1 protein CTD PMID:29098808 NCBI chr20:3,405,017...3,419,831
Ensembl chr20:3,404,711...3,419,831
JBrowse link
G Mecom MDS1 and EVI1 complex locus decreases expression ISO casticin results in decreased expression of MECOM mRNA CTD PMID:28444820 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769
JBrowse link
G Mest mesoderm specific transcript increases expression ISO casticin results in increased expression of MEST mRNA CTD PMID:28444820 NCBI chr 4:58,052,786...58,063,227
Ensembl chr 4:58,053,041...58,063,138
JBrowse link
G Mettl3 methyltransferase-like 3 decreases expression ISO casticin results in decreased expression of METTL3 mRNA CTD PMID:28444820 NCBI chr15:28,710,299...28,721,491
Ensembl chr15:28,710,300...28,721,127
JBrowse link
G Mir148a microRNA 148a increases expression
multiple interactions
ISO casticin results in increased expression of MIR148A mRNA
casticin affects the reaction [MIR148A mRNA affects the activity of DNMT1 protein]; casticin affects the reaction [MIR148A mRNA affects the expression of CD44 mRNA]; casticin affects the reaction [MIR148A mRNA affects the expression of DNMT1 mRNA]; casticin affects the reaction [MIR148A mRNA results in increased expression of MIR148A mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased activity of DNMT1 protein]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of BMI1 mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of CD44 protein]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of EPCAM mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of NANOG mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of POU5F1 mRNA]; DNMT1 protein inhibits the reaction [casticin results in increased expression of MIR148A mRNA]; MIR148A mRNA affects the reaction [casticin results in decreased activity of DNMT1 protein]; MIR148A mRNA affects the reaction [casticin results in decreased expression of DNMT1 mRNA]; MIR148A mRNA affects the reaction [casticin results in increased expression of MIR148A mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased activity of DNMT1 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of BMI1 mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of CD44 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of EPCAM mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of NANOG mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of POU5F1 mRNA]
CTD PMID:32268151 NCBI chr 4:81,013,269...81,013,365
Ensembl chr 4:81,013,269...81,013,365
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO casticin results in decreased expression of MMP2 mRNA
casticin results in decreased expression of MMP2 protein
CTD PMID:27862857, PMID:28444820 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO casticin results in decreased expression of MMP9 protein CTD PMID:28444820 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mplkip M-phase specific PLK1 interacting protein decreases expression ISO casticin results in decreased expression of MPLKIP mRNA CTD PMID:28444820 NCBI chr17:49,955,060...49,990,982
Ensembl chr17:49,955,060...49,991,059
JBrowse link
G mrpl9 mitochondrial ribosomal protein L9 increases expression ISO casticin results in increased expression of MRPL9 mRNA CTD PMID:28444820 NCBI chr 2:195,684,750...195,689,470
Ensembl chr 2:195,684,210...195,689,052
JBrowse link
G Muc13 mucin 13, cell surface associated increases expression ISO casticin results in increased expression of MUC13 mRNA CTD PMID:27862857 NCBI chr11:70,185,757...70,223,012
Ensembl chr11:70,185,757...70,211,701
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression ISO casticin results in increased expression of MYD88 mRNA CTD PMID:27862857 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Myo7a myosin VIIA increases expression ISO casticin results in increased expression of MYO7A mRNA CTD PMID:28444820 NCBI chr 1:163,001,313...163,071,545
Ensembl chr 1:163,001,875...163,071,508
JBrowse link
G Nanog Nanog homeobox multiple interactions
decreases expression
ISO casticin promotes the reaction [MIR148A mRNA results in decreased expression of NANOG mRNA]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of NANOG protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of NANOG mRNA] CTD PMID:32268151 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO casticin results in decreased expression of NARS mRNA CTD PMID:28444820 NCBI chr18:59,986,350...60,002,644
Ensembl chr18:59,986,360...60,002,569
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO casticin results in decreased expression of NDUFS4 mRNA CTD PMID:28444820 NCBI chr 2:46,372,488...46,476,162
Ensembl chr 2:46,372,518...46,476,203
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO casticin results in decreased expression of NFKB1 mRNA CTD PMID:27862857 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 decreases expression ISO casticin results in decreased expression of NFKB2 mRNA CTD PMID:27862857 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO casticin results in decreased expression of NFKBIA mRNA CTD PMID:27862857 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta decreases expression ISO casticin results in decreased expression of NFKBIB mRNA CTD PMID:27862857 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Nfkbid NFKB inhibitor delta decreases expression ISO casticin results in decreased expression of NFKBID mRNA CTD PMID:27862857 NCBI chr 1:88,883,816...88,892,543
Ensembl chr 1:88,885,937...88,892,615
JBrowse link
G Nfkbie NFKB inhibitor epsilon decreases expression ISO casticin results in decreased expression of NFKBIE mRNA CTD PMID:27862857 NCBI chr 9:17,828,405...17,835,240
Ensembl chr 9:17,828,408...17,835,240
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 increases expression ISO casticin results in increased expression of NFX1 mRNA CTD PMID:28444820 NCBI chr 5:57,290,916...57,348,720
Ensembl chr 5:57,291,156...57,348,720
JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 increases expression ISO casticin results in increased expression of NKD1 mRNA CTD PMID:27862857 NCBI chr19:19,434,720...19,509,087
Ensembl chr19:19,436,333...19,509,087
JBrowse link
G Nme9 NME/NM23 family member 9 increases expression ISO casticin results in increased expression of NME9 mRNA CTD PMID:28444820 NCBI chr 8:107,698,612...107,720,758 JBrowse link
G Nmt1 N-myristoyltransferase 1 decreases expression ISO casticin results in decreased expression of NMT1 mRNA CTD PMID:28444820 NCBI chr10:91,126,689...91,160,721
Ensembl chr10:91,126,689...91,160,720
JBrowse link
G Nol4l nucleolar protein 4-like decreases expression ISO casticin results in decreased expression of NOL4L mRNA CTD PMID:28444820 NCBI chr 3:148,905,677...148,940,426
Ensembl chr 3:148,909,826...148,932,878
JBrowse link
G Nop58 NOP58 ribonucleoprotein decreases expression ISO casticin results in decreased expression of NOP58 mRNA CTD PMID:28444820 NCBI chr 9:66,495,881...66,520,521
Ensembl chr 9:66,495,832...66,519,788
JBrowse link
G Npas3 neuronal PAS domain protein 3 decreases expression ISO casticin results in decreased expression of NPAS3 mRNA CTD PMID:28444820 NCBI chr 6:74,081,995...74,913,025 JBrowse link
G Nrg3 neuregulin 3 decreases expression ISO casticin results in decreased expression of NRG3 mRNA CTD PMID:27862857 NCBI chr16:15,763,031...16,932,208
Ensembl chr16:15,764,632...15,798,974
JBrowse link
G Nup205 nucleoporin 205 decreases expression ISO casticin results in decreased expression of NUP205 mRNA CTD PMID:28444820 NCBI chr 4:62,703,779...62,773,931
Ensembl chr 4:62,703,779...62,773,923
JBrowse link
G Nup37 nucleoporin 37 decreases expression ISO casticin results in decreased expression of NUP37 mRNA CTD PMID:28444820 NCBI chr 7:28,715,299...28,750,978
Ensembl chr 7:28,701,690...28,743,326
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 decreases expression ISO casticin results in decreased expression of OLIG2 mRNA CTD PMID:27862857 NCBI chr11:31,389,514...31,392,890
Ensembl chr11:31,389,514...31,392,890
JBrowse link
G Orc5 origin recognition complex, subunit 5 decreases expression ISO casticin results in decreased expression of ORC5 mRNA CTD PMID:28444820 NCBI chr 4:9,160,050...9,223,998
Ensembl chr 4:9,160,067...9,223,997
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 decreases expression ISO casticin results in decreased expression of OTUB2 mRNA CTD PMID:28444820 NCBI chr 6:127,282,445...127,301,086
Ensembl chr 6:127,282,466...127,301,083
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression ISO casticin results in increased expression of P2RX7 mRNA CTD PMID:28444820 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO casticin results in decreased expression of PAIP1 mRNA CTD PMID:28444820 NCBI chr 2:52,300,921...52,328,212
Ensembl chr 2:52,301,798...52,328,205
JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 decreases expression ISO casticin results in decreased expression of PAK3 mRNA CTD PMID:27862857 NCBI chr  X:114,784,452...115,042,683
Ensembl chr  X:114,929,029...115,036,669
JBrowse link
G Papola poly (A) polymerase alpha decreases expression ISO casticin results in decreased expression of PAPOLA mRNA CTD PMID:28444820 NCBI chr 6:129,609,068...129,662,002
Ensembl chr 6:129,609,074...129,661,531
JBrowse link
G Pcdha1 protocadherin alpha 1 increases expression ISO casticin results in increased expression of PCDHA1 mRNA CTD PMID:28444820 NCBI chr18:29,951,094...30,215,896 JBrowse link
G Phf10 PHD finger protein 10 decreases expression ISO casticin results in decreased expression of PHF10 mRNA CTD PMID:28444820 NCBI chr 1:56,951,516...56,967,893
Ensembl chr 1:56,951,518...56,967,895
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein decreases expression ISO casticin results in decreased expression of PICALM mRNA CTD PMID:28444820 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425
JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO casticin results in decreased expression of PLAU protein CTD PMID:28444820 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pmp22 peripheral myelin protein 22 increases expression ISO casticin results in increased expression of PMP22 mRNA CTD PMID:28444820 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions
decreases expression
ISO casticin promotes the reaction [MIR148A mRNA results in decreased expression of POU5F1 mRNA]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of POU5F1 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of POU5F1 mRNA] CTD PMID:32268151 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO casticin results in decreased expression of PPARD mRNA CTD PMID:27862857 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO casticin results in increased expression of PPARG mRNA CTD PMID:27862857 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression ISO casticin results in decreased expression of PPARGC1A mRNA CTD PMID:28444820 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 decreases expression ISO casticin results in decreased expression of PPP1R11 mRNA CTD PMID:28444820 NCBI chr20:2,094,931...2,098,438
Ensembl chr20:2,094,931...2,098,433
JBrowse link
G Ppp6r3 protein phosphatase 6, regulatory subunit 3 decreases expression ISO casticin results in decreased expression of PPP6R3 mRNA CTD PMID:28444820 NCBI chr 1:218,695,738...218,810,139
Ensembl chr 1:218,695,738...218,810,135
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta decreases expression ISO casticin results in decreased expression of PRKAR2B mRNA CTD PMID:27862857 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression ISO casticin results in decreased expression of PRKDC protein CTD PMID:29098808 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Prss44 serine protease 44 increases expression ISO casticin results in increased expression of PRSS44 mRNA CTD PMID:28444820 NCBI chr 8:119,083,900...119,097,707
Ensembl chr 8:119,083,900...119,097,707
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO casticin results in decreased expression of PTK2 protein CTD PMID:28444820 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Ptpra protein tyrosine phosphatase, receptor type, A increases expression ISO casticin results in increased expression of PTPRA mRNA CTD PMID:28444820 NCBI chr 3:122,976,066...123,084,585
Ensembl chr 3:122,976,104...123,084,863
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D decreases expression ISO casticin results in decreased expression of PTPRD mRNA CTD PMID:28444820 NCBI chr 5:92,862,229...93,514,071
Ensembl chr 5:92,862,267...93,244,202
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F decreases expression ISO casticin results in decreased expression of PTPRF mRNA CTD PMID:28444820 NCBI chr 5:137,036,936...137,112,930
Ensembl chr 5:137,036,935...137,112,927
JBrowse link
G Qk quaking decreases expression ISO casticin results in decreased expression of QK mRNA CTD PMID:28444820 NCBI chr 1:50,983,647...51,050,692 JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO casticin results in decreased expression of RAPGEF4 mRNA CTD PMID:28444820 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038
JBrowse link
G Rars1 arginyl-tRNA synthetase 1 decreases expression ISO casticin results in decreased expression of RARS mRNA CTD PMID:28444820 NCBI chr10:20,633,630...20,658,074
Ensembl chr10:20,633,632...20,658,100
JBrowse link
G Rbmx2 RNA binding motif protein, X-linked 2 decreases expression ISO casticin results in decreased expression of RBMX2 mRNA CTD PMID:28444820 NCBI chr  X:135,550,931...135,558,440
Ensembl chr  X:135,550,834...135,558,440
JBrowse link
G Rcor3 REST corepressor 3 decreases expression ISO casticin results in decreased expression of RCOR3 mRNA CTD PMID:28444820 NCBI chr13:110,822,149...110,864,469
Ensembl chr13:110,822,150...110,864,469
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression ISO casticin results in decreased expression of RELA protein CTD PMID:28444820 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rexo2 RNA exonuclease 2 decreases expression ISO casticin results in decreased expression of REXO2 mRNA CTD PMID:28444820 NCBI chr 8:52,802,604...52,814,321
Ensembl chr 8:52,802,595...52,814,321
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO casticin results in decreased expression of RHOA protein CTD PMID:28444820 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rpl22l1 ribosomal protein L22 like 1 decreases expression ISO casticin results in decreased expression of RPL22L1 mRNA CTD PMID:28444820 NCBI chr 2:115,362,799...115,364,735
Ensembl chr 2:115,362,799...115,364,729
JBrowse link
G S100a13 S100 calcium binding protein A13 increases expression ISO casticin results in increased expression of S100A13 mRNA CTD PMID:28444820 NCBI chr 2:189,906,022...189,912,516
Ensembl chr 2:189,906,022...189,912,516
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 increases expression ISO casticin results in increased expression of SCN1B mRNA CTD PMID:28444820 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Slc31a1 solute carrier family 31 member 1 increases expression ISO casticin results in increased expression of SLC31A1 mRNA CTD PMID:28444820 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO casticin results in decreased expression of SLC6A9 mRNA CTD PMID:28444820 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link
G Smad1 SMAD family member 1 increases expression ISO casticin results in increased expression of SMAD1 mRNA CTD PMID:27862857 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smad3 SMAD family member 3 increases expression ISO casticin results in increased expression of SMAD3 mRNA CTD PMID:27862857 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G decreases expression ISO casticin results in decreased expression of SNRPG mRNA CTD PMID:28444820 NCBI chr 4:118,167,267...118,174,846
Ensembl chr 4:118,167,294...118,174,842
JBrowse link
G Snw1 SNW domain containing 1 decreases expression ISO casticin results in decreased expression of SNW1 mRNA CTD PMID:28444820 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 decreases expression ISO casticin results in decreased expression of SOS1 protein CTD PMID:28444820 NCBI chr 6:3,105,443...3,182,977
Ensembl chr 6:3,104,861...3,182,996
JBrowse link
G Sparc secreted protein acidic and cysteine rich decreases expression
increases expression
ISO casticin results in decreased expression of SPARC mRNA
casticin results in increased expression of SPARC mRNA
CTD PMID:27862857, PMID:28444820 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Sparcl1 SPARC like 1 increases expression ISO casticin results in increased expression of SPARCL1 mRNA CTD PMID:28444820 NCBI chr14:6,994,261...7,025,309
Ensembl chr14:6,994,190...7,025,308
JBrowse link
G St13 ST13, Hsp70 interacting protein increases expression ISO casticin results in increased expression of ST13 mRNA CTD PMID:28444820 NCBI chr 7:122,585,770...122,635,731
Ensembl chr 7:122,585,771...122,635,731
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression ISO casticin results in decreased expression of ST3GAL3 mRNA CTD PMID:28444820 NCBI chr 5:136,765,309...136,965,642
Ensembl chr 5:136,766,208...136,965,191
JBrowse link
G Strbp spermatid perinuclear RNA binding protein decreases expression ISO casticin results in decreased expression of STRBP mRNA CTD PMID:28444820 NCBI chr 3:21,817,680...21,956,988
Ensembl chr 3:21,828,298...21,904,270
JBrowse link
G Sugp1 SURP and G patch domain containing 1 decreases expression ISO casticin results in decreased expression of SUGP1 mRNA CTD PMID:28444820 NCBI chr16:21,100,923...21,131,795
Ensembl chr16:21,100,924...21,131,795
JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein decreases expression ISO casticin results in decreased expression of SYNCRIP mRNA CTD PMID:28444820 NCBI chr 8:96,100,692...96,266,342
Ensembl chr 8:96,105,025...96,266,342
JBrowse link
G Syt9 synaptotagmin 9 decreases expression ISO casticin results in decreased expression of SYT9 mRNA CTD PMID:28444820 NCBI chr 1:171,592,703...171,769,780
Ensembl chr 1:171,592,797...171,769,780
JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 decreases expression ISO casticin results in decreased expression of TAB2 mRNA CTD PMID:27862857 NCBI chr 1:1,999,574...2,017,574
Ensembl chr 1:1,999,596...2,073,896
JBrowse link
G Tcf7 transcription factor 7 decreases expression ISO casticin results in decreased expression of TCF7 mRNA CTD PMID:28444820 NCBI chr10:37,616,033...37,646,027
Ensembl chr10:37,617,279...37,645,802
JBrowse link
G Thra thyroid hormone receptor alpha decreases expression ISO casticin results in decreased expression of THRA mRNA CTD PMID:28444820 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO casticin results in increased expression of TIMP2 mRNA CTD PMID:28444820 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tlk2 tousled-like kinase 2 decreases expression ISO casticin results in decreased expression of TLK2 mRNA CTD PMID:28444820 NCBI chr10:93,410,181...93,507,277
Ensembl chr10:93,415,399...93,507,277
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO casticin results in decreased expression of TLR4 mRNA CTD PMID:27862857 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmbim4 transmembrane BAX inhibitor motif containing 4 increases expression ISO casticin results in increased expression of TMBIM4 mRNA CTD PMID:27862857 NCBI chr 7:64,987,859...65,002,447
Ensembl chr 7:64,987,859...65,002,455
JBrowse link
G Tmem45b transmembrane protein 45b increases expression ISO casticin results in increased expression of TMEM45B mRNA CTD PMID:27862857 NCBI chr 8:32,563,872...32,609,212
Ensembl chr 8:32,563,874...32,609,212
JBrowse link
G Tmsb10 thymosin, beta 10 increases expression ISO casticin results in increased expression of TMSB10 mRNA CTD PMID:28444820 NCBI chr 4:100,882,216...100,883,303
Ensembl chr 4:100,882,216...100,883,275
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO casticin results in increased expression of TNFSF10 protein CTD PMID:27862857 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnpo1 transportin 1 decreases expression ISO casticin results in decreased expression of TNPO1 mRNA CTD PMID:28444820 NCBI chr 2:29,056,219...29,126,882
Ensembl chr 2:29,056,219...29,121,104
JBrowse link
G Tor1aip2 torsin 1A interacting protein 2 decreases expression ISO casticin results in decreased expression of TOR1AIP2 mRNA CTD PMID:28444820 NCBI chr13:73,704,088...73,735,339
Ensembl chr13:73,708,815...73,735,339
Ensembl chr13:73,708,815...73,735,339
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
ISO casticin results in increased expression of TP53 protein modified form
casticin results in decreased expression of TP53 protein
CTD PMID:29098808 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO casticin results in increased expression of TPI1 mRNA CTD PMID:28444820 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
JBrowse link
G Tpra1 transmembrane protein adipocyte associated 1 increases expression ISO casticin results in increased expression of TPRA1 mRNA CTD PMID:28444820 NCBI chr 4:120,843,374...120,854,534
Ensembl chr 4:120,843,453...120,854,529
JBrowse link
G Tra2b transformer 2 beta homolog decreases expression ISO casticin results in decreased expression of TRA2B mRNA CTD PMID:28444820 NCBI chr11:82,373,828...82,392,208
Ensembl chr11:82,373,870...82,392,083
JBrowse link
G Trap1 TNF receptor-associated protein 1 increases expression ISO casticin results in increased expression of TRAP1 mRNA CTD PMID:27862857 NCBI chr10:11,724,032...11,757,682
Ensembl chr10:11,724,032...11,757,681
JBrowse link
G Trio trio Rho guanine nucleotide exchange factor increases expression ISO casticin results in increased expression of TRIO mRNA CTD PMID:28444820 NCBI chr 2:80,471,398...80,769,313
Ensembl chr 2:80,473,202...80,667,481
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 decreases expression ISO casticin results in decreased expression of UBE2D3 mRNA CTD PMID:28444820 NCBI chr 2:240,626,198...240,655,874
Ensembl chr 2:240,627,436...240,655,246
JBrowse link
G Ube2f ubiquitin-conjugating enzyme E2F (putative) decreases expression ISO casticin results in decreased expression of UBE2F mRNA CTD PMID:28444820 NCBI chr 9:98,394,112...98,428,684
Ensembl chr 9:98,398,128...98,428,128
JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W decreases expression ISO casticin results in decreased expression of UBE2W mRNA CTD PMID:28444820 NCBI chr 5:29,798,845...29,812,777 JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO casticin results in decreased expression of VEGFA mRNA CTD PMID:28444820 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vezf1 vascular endothelial zinc finger 1 decreases expression ISO casticin results in decreased expression of VEZF1 mRNA CTD PMID:28444820 NCBI chr10:75,365,763...75,382,014
Ensembl chr10:75,365,822...75,381,555
JBrowse link
G Vim vimentin decreases expression
increases expression
ISO casticin results in decreased expression of VIM mRNA
casticin results in increased expression of VIM mRNA
CTD PMID:27862857, PMID:28444820 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vldlr very low density lipoprotein receptor decreases expression ISO casticin results in decreased expression of VLDLR mRNA CTD PMID:28444820 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Wac WW domain containing adaptor with coiled-coil decreases expression ISO casticin results in decreased expression of WAC mRNA CTD PMID:28444820 NCBI chr17:60,887,606...60,946,630
Ensembl chr17:60,888,017...60,946,426
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression ISO casticin results in decreased expression of WEE1 protein CTD PMID:29098808 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
JBrowse link
G Wnt5a Wnt family member 5A decreases expression ISO casticin results in decreased expression of WNT5A mRNA CTD PMID:27862857 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 decreases expression ISO casticin results in decreased expression of WSB1 mRNA CTD PMID:28444820 NCBI chr10:66,586,905...66,602,984
Ensembl chr10:66,586,924...66,602,987
JBrowse link
G Wtap WT1 associated protein decreases expression ISO casticin results in decreased expression of WTAP mRNA CTD PMID:28444820 NCBI chr 1:47,942,500...47,967,633
Ensembl chr 1:47,942,500...47,967,631
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO casticin results in increased expression of XBP1 mRNA CTD PMID:27862857 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO casticin results in decreased expression of XIAP protein CTD PMID:29098808 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta increases expression ISO casticin results in increased expression of YWHAB protein CTD PMID:29098808 NCBI chr 3:160,391,108...160,399,931
Ensembl chr 3:160,391,106...160,399,931
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma decreases expression ISO casticin results in decreased expression of YWHAG mRNA CTD PMID:28444820 NCBI chr12:23,789,547...23,817,884
Ensembl chr12:23,789,638...23,817,883
JBrowse link
G Zbtb18 zinc finger and BTB domain containing 18 decreases expression ISO casticin results in decreased expression of ZBTB18 mRNA CTD PMID:28444820 NCBI chr13:95,582,234...95,593,316
Ensembl chr13:95,589,668...95,591,236
JBrowse link
G Zfhx4 zinc finger homeobox 4 decreases expression ISO casticin results in decreased expression of ZFHX4 mRNA CTD PMID:28444820 NCBI chr 2:98,423,565...98,610,368
Ensembl chr 2:98,423,569...98,610,368
JBrowse link
G Zfp384 zinc finger protein 384 decreases expression ISO casticin results in decreased expression of ZFP384 mRNA CTD PMID:28444820 NCBI chr 4:157,523,083...157,552,606
Ensembl chr 4:157,523,110...157,552,596
JBrowse link
G Zfp711 zinc finger protein 711 decreases expression ISO casticin results in decreased expression of ZFP711 mRNA CTD PMID:28444820 NCBI chr  X:84,062,363...84,095,888
Ensembl chr  X:84,064,427...84,096,617
JBrowse link
G Zfr zinc finger RNA binding protein decreases expression ISO casticin results in decreased expression of ZFR mRNA CTD PMID:28444820 NCBI chr 2:62,150,251...62,213,048
Ensembl chr 2:62,150,251...62,213,048
JBrowse link
G Zkscan1 zinc finger with KRAB and SCAN domains 1 increases expression ISO casticin results in increased expression of ZKSCAN1 mRNA CTD PMID:28444820 NCBI chr12:19,231,092...19,247,393
Ensembl chr12:19,231,092...19,247,387
JBrowse link
G Zscan2 zinc finger and SCAN domain containing 2 increases expression ISO casticin results in increased expression of ZSCAN2 mRNA CTD PMID:28444820 NCBI chr 1:142,679,308...142,695,232
Ensembl chr 1:142,679,345...142,695,475
JBrowse link
G Zswim6 zinc finger, SWIM-type containing 6 increases expression ISO casticin results in increased expression of ZSWIM6 mRNA CTD PMID:28444820 NCBI chr 2:38,978,042...39,042,886
Ensembl chr 2:38,979,865...39,007,976
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        biochemical role 19304
          apoptosis inducer 10981
            casticin 274
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  oxacycle 17200
                                    benzopyran 10149
                                      1-benzopyran 9865
                                        flavonoid 6381
                                          flavones 4171
                                            hydroxyflavone 4159
                                              flavonols 4073
                                                7-hydroxyflavonol 4052
                                                  quercetin 4001
                                                    quercetagetin 280
                                                      casticin 274
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.