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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:falcarindiol
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Accession:CHEBI:69236 term browser browse the term
Definition:An organic molecular entity that has formula C17H24O2.
Synonyms:related_synonym: (3S,8S,9Z)-heptadeca-1,9-dien-4,6-diyne-3,8-diol;   Falcalindiol;   Formula=C17H24O2;   InChI=1S/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3/b14-10-/t16-,17-/m0/s1;   InChIKey=QWCNQXNAFCBLLV-RCQSYPNMSA-N;   SMILES=CCCCCCC\\C=C/[C@H](O)C#CC#C[C@@H](O)C=C
 alt_id: CHEBI:4971
 xref: CAS:55297-87-5;   HMDB:HMDB0033941;   KEGG:C08449;   KNApSAcK:C00001283
 xref_mesh: MESH:C034379
 xref: PMID:21800857


show annotations for term's descendants           Sort by:
falcarindiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Keap1 Kelch-like ECH-associated protein 1 affects folding
multiple interactions
decreases activity		 EXP falcarindiol affects the folding of KEAP1 protein
falcarindiol binds to and results in increased alkylation of KEAP1 protein; falcarindiol inhibits the reaction [KEAP1 protein results in decreased activity of NFE2L2 protein]; Glutathione inhibits the reaction [falcarindiol binds to and results in increased alkylation of KEAP1 protein]
falcarindiol results in decreased activity of KEAP1 protein		 CTD PMID:20026152 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP falcarindiol inhibits the reaction [KEAP1 protein results in decreased activity of NFE2L2 protein] CTD PMID:20026152 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          metabolite 19537
            falcarindiol 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      p-block molecular entity 19811
                        carbon group molecular entity 19751
                          organic molecular entity 19748
                            falcarindiol 2
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