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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:falcarindiol
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Accession:CHEBI:69236 term browser browse the term
Definition:An organic molecular entity that has formula C17H24O2.
Synonyms:related_synonym: (3S,8S,9Z)-heptadeca-1,9-dien-4,6-diyne-3,8-diol;   Falcalindiol;   Formula=C17H24O2;   InChI=1S/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3/b14-10-/t16-,17-/m0/s1;   InChIKey=QWCNQXNAFCBLLV-RCQSYPNMSA-N;   SMILES=CCCCCCC\\C=C/[C@H](O)C#CC#C[C@@H](O)C=C
 alt_id: CHEBI:4971
 xref: CAS:55297-87-5;   HMDB:HMDB0033941;   KEGG:C08449;   KNApSAcK:C00001283
 xref_mesh: MESH:C034379
 xref: PMID:21800857


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falcarindiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Keap1 Kelch-like ECH-associated protein 1 affects folding
multiple interactions
decreases activity
EXP falcarindiol affects the folding of KEAP1 protein
falcarindiol binds to and results in increased alkylation of KEAP1 protein; falcarindiol inhibits the reaction [KEAP1 protein results in decreased activity of NFE2L2 protein]; Glutathione inhibits the reaction [falcarindiol binds to and results in increased alkylation of KEAP1 protein]
falcarindiol results in decreased activity of KEAP1 protein
CTD PMID:20026152 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP falcarindiol inhibits the reaction [KEAP1 protein results in decreased activity of NFE2L2 protein] CTD PMID:20026152 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            falcarindiol 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      p-block molecular entity 19672
                        carbon group molecular entity 19574
                          organic molecular entity 19563
                            falcarindiol 2
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