Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:desoximetasone
go back to main search page
Accession:CHEBI:691037 term browser browse the term
Definition:Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis.
Synonyms:exact_synonym: 9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
 related_synonym: (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione;   9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone;   Formula=C22H29FO4;   InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1;   InChIKey=VWVSBHGCDBMOOT-IIEHVVJPSA-N;   SMILES=[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C;   desoximetasona;   desoximetasonum;   desoxymethasone
 xref: Beilstein:2228097;   CAS:382-67-2;   DrugBank:DB00547;   Drug_Central:819;   KEGG:D03697
 xref_mesh: MESH:D003899
 xref: Patent:BE314196;   Patent:FR1296544;   Patent:US3099654;   Patent:US3232839;   Wikipedia:Desoximetasone


show annotations for term's descendants       view all columns           Sort by:
 
desoximetasone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      application 19359
        anti-inflammatory agent 14958
          anti-inflammatory drug 13610
            desoximetasone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic group 18428
                              organic divalent group 18419
                                organodiyl group 18419
                                  carbonyl group 18309
                                    carbonyl compound 18309
                                      ketone 15948
                                        oxyketone 8487
                                          alpha-oxyketone 8487
                                            alpha-hydroxy ketone 8487
                                              primary alpha-hydroxy ketone 7450
                                                desoximetasone 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.