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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:69098 term browser browse the term
Definition:A member of the class of 1-benzofurans which consists of 1-benzofuran substituted by a hydroxy group at position 6, a methoxy group at position 4, a prenyl group at position 5 and a 2,4-dihydroxyphenyl group at position 2. It has been isolated from Glycyrrhiza uralensis.
Synonyms:exact_synonym: 4-[6-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)-1-benzofuran-2-yl]benzene-1,3-diol
 related_synonym: 2-(2',4'-dihydroxyphenyl)-6-hydroxy-5-isopentenyl-4-methoxybenzofuran;   Formula=C20H20O5;   InChI=1S/C20H20O5/c1-11(2)4-6-14-17(23)10-19-15(20(14)24-3)9-18(25-19)13-7-5-12(21)8-16(13)22/h4-5,7-10,21-23H,6H2,1-3H3;   InChIKey=CNPMAFLUEHEXRE-UHFFFAOYSA-N;   SMILES=COc1c(CC=C(C)C)c(O)cc2oc(cc12)-c1ccc(O)cc1O
 xref: HMDB:HMDB0038755;   LIPID_MAPS_instance:LMPK12160045
 xref_mesh: MESH:C000617177
 xref: PMID:10993226;   PMID:12392103;   PMID:1913999;   PMID:1941536;   PMID:20724155;   PMID:22074222;   PMID:2632045;   Reaxys:4821696

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licocoumarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A multiple interactions ISO licocoumarone binds to and results in decreased activity of DYRK1A protein CTD PMID:31838052 NCBI chr11:34,858,339...34,958,733
Ensembl chr11:34,865,532...34,956,536
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression ISO licocoumarone results in decreased expression of MET protein CTD PMID:31838052 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      biological role 19720
        antimicrobial agent 17372
          antibacterial agent 13450
            licocoumarone 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic molecule 19504
                              organic cyclic compound 19331
                                organic heterocyclic compound 18519
                                  organic heteropolycyclic compound 17978
                                    organic heterobicyclic compound 16778
                                      mancude organic heterobicyclic parent 5212
                                        benzofuran 20
                                          1-benzofuran 20
                                            licocoumarone 2
paths to the root