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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:69098 term browser browse the term
Definition:A member of the class of 1-benzofurans which consists of 1-benzofuran substituted by a hydroxy group at position 6, a methoxy group at position 4, a prenyl group at position 5 and a 2,4-dihydroxyphenyl group at position 2. It has been isolated from Glycyrrhiza uralensis.
Synonyms:exact_synonym: 4-[6-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)-1-benzofuran-2-yl]benzene-1,3-diol
 related_synonym: 2-(2',4'-dihydroxyphenyl)-6-hydroxy-5-isopentenyl-4-methoxybenzofuran;   Formula=C20H20O5;   InChI=1S/C20H20O5/c1-11(2)4-6-14-17(23)10-19-15(20(14)24-3)9-18(25-19)13-7-5-12(21)8-16(13)22/h4-5,7-10,21-23H,6H2,1-3H3;   InChIKey=CNPMAFLUEHEXRE-UHFFFAOYSA-N;   SMILES=COc1c(CC=C(C)C)c(O)cc2oc(cc12)-c1ccc(O)cc1O
 xref: HMDB:HMDB0038755;   LIPID_MAPS_instance:LMPK12160045
 xref_mesh: MESH:C000617177
 xref: PMID:10993226;   PMID:12392103;   PMID:1913999;   PMID:1941536;   PMID:20724155;   PMID:22074222;   PMID:2632045;   Reaxys:4821696

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licocoumarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A multiple interactions ISO licocoumarone binds to and results in decreased activity of DYRK1A protein CTD PMID:31838052 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression ISO licocoumarone results in decreased expression of MET protein CTD PMID:31838052 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      biological role 19805
        antimicrobial agent 18125
          antibacterial agent 15444
            licocoumarone 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            organic molecule 19677
                              organic cyclic compound 19490
                                organic heterocyclic compound 18852
                                  organic heteropolycyclic compound 18295
                                    organic heterobicyclic compound 17240
                                      mancude organic heterobicyclic parent 8324
                                        benzofuran 20
                                          1-benzofuran 20
                                            licocoumarone 2
paths to the root