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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glycyrin
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Accession:CHEBI:69086 term browser browse the term
Definition:A member of the class of coumarins that is coumarin substituted by methoxy groups at positions 5 and 7, a prenyl group at position 6 and a 2,4-dihydroxyphenyl group at position 3. Isolated from Glycyrrhiza uralensis, it exhibits antibacterial activity.
Synonyms:exact_synonym: 3-(2,4-dihydroxyphenyl)-5,7-dimethoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
 related_synonym: 3-(2',4'-dihydroxyphenyl)-5,7-dimethoxy-2-isopentenylcoumarin;   3-(2,4-dihydroxyphenyl)-5,7-dimethoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-2-one;   3-(2,4-dihydroxyphenyl)-5,7-dimethoxy-6-prenylcoumarin;   Formula=C22H22O6;   InChI=1S/C22H22O6/c1-12(2)5-7-15-19(26-3)11-20-17(21(15)27-4)10-16(22(25)28-20)14-8-6-13(23)9-18(14)24/h5-6,8-11,23-24H,7H2,1-4H3;   InChIKey=FWWGXZYUURXJLK-UHFFFAOYSA-N;   SMILES=COc1cc2oc(=O)c(cc2c(OC)c1CC=C(C)C)-c1ccc(O)cc1O
 xref: CAS:66056-18-6;   HMDB:HMDB0033712;   LIPID_MAPS_instance:LMPK12160017
 xref_mesh: MESH:C000602096
 xref: PMID:11575586;   PMID:12127165;   PMID:14608046;   PMID:14643306;   PMID:22074222;   Patent:WO2004064830;   Reaxys:1667250


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glycyrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A decreases activity ISO glycyrin results in decreased activity of DYRK1A protein CTD PMID:31838052 NCBI chr11:34,858,339...34,958,733
Ensembl chr11:34,865,532...34,956,536
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Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      biological role 19723
        biochemical role 19311
          metabolite 19293
            glycyrin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic molecule 19505
                              organic cyclic compound 19332
                                organic heterocyclic compound 18519
                                  oxacycle 17539
                                    benzopyran 10269
                                      1-benzopyran 9991
                                        chromenes 931
                                          chromenone 861
                                            coumarins 580
                                              glycyrin 1
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