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ONTOLOGY REPORT - ANNOTATIONS


Term:longirostrerone C
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Accession:CHEBI:68982 term browser browse the term
Definition:An azaphilone that is 9,9a-dihydro-6H-furo[2,3-h]isochromene-6,8(6aH)-dione substituted by a 6-methyl-2-oxocyclohex-3-en-1-yl group at position 3, a methyl group at position 6a and a 4,6,8-trimethyldeca-2,4-dienoyl group at position 9. Isolated from Chaetomium longirostre, it exhibits cytotoxic and antimalarial activities.
Synonyms:exact_synonym: (6aR,9S,9aR)-6a-methyl-3-[(1S,6S)-6-methyl-2-oxocyclohex-3-en-1-yl]-9-[(2E,4E)-4,6,8-trimethyldeca-2,4-dienoyl]-9,9a-dihydro-6H-furo[2,3-h]isochromene-6,8(6aH)-dione
 related_synonym: 3-(6-methyl-2-oxocyclohex-3-enyl)-18-(4,6,8-trimethyldeca-2,4-dienoyl)-(7R)-7-methyl-8,18-dihydro-7H-furo[2,3-h]isochromene-6,17-dione;   Formula=C32H38O6;   InChI=1S/C32H38O6/c1-7-18(2)13-20(4)14-19(3)11-12-25(34)29-30-23-17-37-26(28-21(5)9-8-10-24(28)33)15-22(23)16-27(35)32(30,6)38-31(29)36/h8,10-12,14-18,20-21,28-30H,7,9,13H2,1-6H3/b12-11+,19-14+/t18?,20?,21-,28+,29+,30-,32-/m0/s1;   InChIKey=HOGGEAXXACLKBX-OPYHNVJQSA-N;   SMILES=CCC(C)CC(C)\\C=C(C)\\C=C\\C(=O)[C@@H]1[C@@H]2C3=COC(=CC3=CC(=O)[C@]2(C)OC1=O)[C@@H]1[C@@H](C)CC=CC1=O
 alt_id: CHEBI:68773
 xref: PMID:22004007 "Europe PMC";   Reaxys:22123573 "Reaxys"


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  CHEBI ontology 19596
    role 19539
      application 19135
        pharmaceutical 19038
          drug 19038
            antineoplastic agent 16533
              longirostrerone C 0
Path 2
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  CHEBI ontology 19596
    subatomic particle 19592
      composite particle 19592
        hadron 19592
          baryon 19592
            nucleon 19592
              atomic nucleus 19592
                atom 19592
                  main group element atom 19471
                    p-block element atom 19471
                      carbon group element atom 19345
                        carbon atom 19337
                          organic molecular entity 19337
                            organic group 18299
                              organic divalent group 18289
                                organodiyl group 18289
                                  carbonyl group 18176
                                    carbonyl compound 18176
                                      carboxylic ester 13615
                                        lactone 5843
                                          gamma-lactone 1188
                                            longirostrerone C 0
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