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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:azilsartan medoxomil
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Accession:CHEBI:68845 term browser browse the term
Definition:A carboxylic ester obtained by formal condensation of the carboxy group of azilsartan with the hydroxy group of 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one. A prodrug for azilsartan, it is used for treatment of hypertension.
Synonyms:exact_synonym: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1-benzimidazole-7-carboxylate
 related_synonym: Edarbi;   Formula=C30H24N4O8;   InChI=1S/C30H24N4O8/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26/h4-14H,3,15-16H2,1-2H3,(H,32,33,36);   InChIKey=QJFSABGVXDWMIW-UHFFFAOYSA-N;   SMILES=CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1;   azilsartan medoxomilo;   azilsartanum medoxomilum
 xref: CAS:863031-21-4;   Drug_Central:4322;   KEGG:D08067;   PMID:21069103;   PMID:21272195;   PMID:21282560;   PMID:21555300;   PMID:21558880;   PMID:21566544;   PMID:21762358;   PMID:21816148;   PMID:21971539;   PMID:21986624;   PMID:22071238;   PMID:22116996;   PMID:22346296;   PMID:22365278;   PMID:22457601;   PMID:22533654;   PMID:22661897;   PMID:22710649;   PMID:22877322;   PMID:22939358;   Patent:US2005187269;   Reaxys:12326818;   Wikipedia:Azilsartan
 cyclic_relationship: is_conjugate_acid_of CHEBI:68849

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  CHEBI ontology 19860
    role 19832
      application 19675
        pro-agent 11550
          prodrug 11310
            azilsartan medoxomil 0
Path 2
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  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            heteroorganic entity 19494
                              organochalcogen compound 19257
                                organooxygen compound 19173
                                  carbon oxoacid 18641
                                    carbonic acid 5618
                                      carbonates 136
                                        carbonate ester 105
                                          cyclic carbonate ester 0
                                            azilsartan medoxomil 0
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