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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:neoechinulin A
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Accession:CHEBI:68794 term browser browse the term
Definition:An organic molecular entity that has formula C19H29N3O2.
Synonyms:alt_id: MESH:C490266
 xref_mesh: MESH:C490266


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neoechinulin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcf1 ATP binding cassette subfamily F member 1 increases expression ISO neoechinulin A results in increased expression of ABCF1 mRNA CTD PMID:19818335 NCBI chr20:3,309,914...3,322,828
Ensembl chr20:3,309,899...3,322,825
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 increases expression ISO neoechinulin A results in increased expression of AIMP1 mRNA CTD PMID:19818335 NCBI chr 2:237,727,782...237,751,327
Ensembl chr 2:237,727,764...237,751,378
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which affects the localization of NFKB1 protein]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which affects the localization of RELA protein]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased abundance of Dinoprostone]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of IL1B mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of IL1B protein]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of IL6 mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of IL6 protein]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of NOS2 mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of NOS2 protein]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of PTGS2 mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of PTGS2 protein]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of TNF mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of TNF protein]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased phosphorylation of MAP3K5 protein] CTD PMID:23261590 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO neoechinulin A results in increased expression of BLVRB mRNA CTD PMID:21356202 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G C3 complement C3 increases expression ISO neoechinulin A results in increased expression of C3 mRNA CTD PMID:19818335 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO neoechinulin A results in increased expression of CCL11 mRNA CTD PMID:19818335 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression ISO neoechinulin A results in increased expression of CCL12 mRNA CTD PMID:21356202 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO neoechinulin A results in increased expression of CCL19 mRNA CTD PMID:19818335 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO neoechinulin A results in decreased expression of CCL2 mRNA CTD PMID:19818335 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 decreases expression
increases expression
ISO neoechinulin A results in decreased expression of CCL20 mRNA
neoechinulin A results in increased expression of CCL20 mRNA
CTD PMID:19818335 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl25 C-C motif chemokine ligand 25 increases expression ISO neoechinulin A results in increased expression of CCL25 mRNA CTD PMID:19818335 NCBI chr12:2,429,492...2,438,928
Ensembl chr12:2,429,509...2,438,817
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression
increases expression
ISO neoechinulin A results in decreased expression of CCL3 mRNA
neoechinulin A results in increased expression of CCL3 mRNA; neoechinulin A results in increased expression of CCL3 protein
CTD PMID:19818335, PMID:21356202 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO neoechinulin A results in decreased expression of CCL4 mRNA CTD PMID:19818335 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO neoechinulin A results in increased expression of CCL5 mRNA CTD PMID:19818335 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO neoechinulin A results in decreased expression of CCL7 mRNA CTD PMID:19818335 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO neoechinulin A results in increased expression of CCR1 mRNA CTD PMID:19818335 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ccr10 C-C motif chemokine receptor 10 increases expression ISO neoechinulin A results in increased expression of CCR10 mRNA CTD PMID:19818335 NCBI chr10:89,086,556...89,088,993
Ensembl chr10:89,086,556...89,088,993
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO neoechinulin A results in increased expression of CCR2 mRNA CTD PMID:19818335
G Ccr6 C-C motif chemokine receptor 6 increases expression ISO neoechinulin A results in increased expression of CCR6 mRNA CTD PMID:19818335 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO neoechinulin A results in increased expression of CCR7 mRNA CTD PMID:19818335 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 increases expression ISO neoechinulin A results in increased expression of CCR9 mRNA CTD PMID:19818335 NCBI chr 8:132,827,325...132,842,130
Ensembl chr 8:132,828,091...132,842,130
JBrowse link
G Cd40lg CD40 ligand increases expression ISO neoechinulin A results in increased expression of CD40LG mRNA CTD PMID:19818335 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Crp C-reactive protein increases expression ISO neoechinulin A results in increased expression of CRP mRNA CTD PMID:19818335 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO neoechinulin A results in increased expression of CX3CL1 mRNA CTD PMID:19818335 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression
increases expression
ISO neoechinulin A results in decreased expression of CXCL10 mRNA
neoechinulin A results in increased expression of CXCL10 protein
CTD PMID:19818335, PMID:21356202 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 decreases expression ISO neoechinulin A results in decreased expression of CXCL13 mRNA CTD PMID:19818335 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO neoechinulin A results in increased expression of CXCL2 mRNA CTD PMID:21356202 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
increases expression
ISO neoechinulin A results in decreased expression of CXCL1 mRNA
neoechinulin A results in increased expression of CXCL1 mRNA
CTD PMID:19818335, PMID:21356202 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression ISO neoechinulin A results in increased expression of CXCR3 mRNA CTD PMID:19818335 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 increases expression ISO neoechinulin A results in increased expression of CXCR5 mRNA CTD PMID:19818335 NCBI chr 8:48,835,688...48,852,032
Ensembl chr 8:48,836,957...48,850,671
JBrowse link
G Il10rb interleukin 10 receptor subunit beta increases expression ISO neoechinulin A results in increased expression of IL10RB mRNA CTD PMID:19818335 NCBI chr11:31,560,301...31,582,457
Ensembl chr11:31,560,530...31,582,457
JBrowse link
G Il16 interleukin 16 increases expression ISO neoechinulin A results in increased expression of IL16 mRNA CTD PMID:19818335 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO neoechinulin A results in decreased expression of IL1A mRNA CTD PMID:19818335 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of IL1B mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of IL1B protein] CTD PMID:23261590 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression ISO neoechinulin A results in increased expression of IL1R1 mRNA CTD PMID:19818335 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il2rb interleukin 2 receptor subunit beta increases expression ISO neoechinulin A results in increased expression of IL2RB mRNA CTD PMID:19818335 NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma increases expression ISO neoechinulin A results in increased expression of IL2RG mRNA CTD PMID:19818335 NCBI chr  X:71,165,378...71,169,078
Ensembl chr  X:71,162,585...71,169,865
JBrowse link
G Il36a interleukin 36, alpha increases expression ISO neoechinulin A results in increased expression of IL1F6 mRNA CTD PMID:19818335 NCBI chr 3:1,330,790...1,335,811
Ensembl chr 3:1,331,226...1,335,775
JBrowse link
G Il5ra interleukin 5 receptor subunit alpha increases expression ISO neoechinulin A results in increased expression of IL5RA mRNA CTD PMID:19818335 NCBI chr 4:138,796,165...138,834,164
Ensembl chr 4:138,795,327...138,830,117
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of IL6 mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of IL6 protein]
neoechinulin A results in increased expression of IL6 mRNA
CTD PMID:21356202, PMID:23261590 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO neoechinulin A results in increased expression of IL6RA mRNA CTD PMID:19818335 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Il6st interleukin 6 signal transducer increases expression ISO neoechinulin A results in increased expression of IL6ST mRNA CTD PMID:19818335 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO neoechinulin A results in increased expression of ITGAM mRNA CTD PMID:19818335 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgb2 integrin subunit beta 2 increases expression ISO neoechinulin A results in increased expression of ITGB2 mRNA CTD PMID:19818335 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G LOC103694381 lymphotoxin-beta increases expression ISO neoechinulin A results in increased expression of LTB mRNA CTD PMID:19818335 NCBI chr20:4,861,343...4,863,513
Ensembl chr20:4,861,335...4,863,198
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased phosphorylation of MAP3K5 protein] CTD PMID:23261590 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which affects the localization of NFKB1 protein] CTD PMID:23261590 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of NOS2 mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of NOS2 protein]
neoechinulin A results in increased expression of NOS2 mRNA
CTD PMID:21356202, PMID:23261590 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pf4 platelet factor 4 increases expression ISO neoechinulin A results in increased expression of PF4 mRNA CTD PMID:19818335 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of PTGS2 mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of PTGS2 protein] CTD PMID:23261590 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which affects the localization of RELA protein] CTD PMID:23261590 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO neoechinulin A results in increased expression of SPP1 mRNA CTD PMID:19818335 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO neoechinulin A results in increased expression of TGFB1 mRNA CTD PMID:19818335 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases expression
ISO neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of TNF mRNA]; neoechinulin A inhibits the reaction [[APP protein binds to APP protein binds to APP protein] which results in increased expression of TNF protein]
neoechinulin A results in increased expression of TNF mRNA
neoechinulin A results in decreased expression of TNF mRNA
CTD PMID:19818335, PMID:21356202, PMID:23261590 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO neoechinulin A results in increased expression of TNFRSF1A mRNA CTD PMID:19818335 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tollip toll interacting protein increases expression ISO neoechinulin A results in increased expression of TOLLIP mRNA CTD PMID:19818335 NCBI chr 1:214,823,993...214,844,861
Ensembl chr 1:214,823,978...214,844,858
JBrowse link
G Xcr1 X-C motif chemokine receptor 1 increases expression ISO neoechinulin A results in increased expression of XCR1 mRNA CTD PMID:19818335 NCBI chr 8:132,911,474...132,919,110
Ensembl chr 8:132,911,486...132,919,110
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            neoechinulin A 57
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      p-block molecular entity 19672
                        carbon group molecular entity 19574
                          organic molecular entity 19563
                            neoechinulin A 57
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.