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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:asperentin
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Accession:CHEBI:68792 term browser browse the term
Definition:A member of the class of isocoumarins that is 6,8-dihydroxy-3,4-dihydro-1H-isochromen-1-one substituted by a [6-methyltetrahydro-2H-pyran-2-yl]methyl group at position 3. It has been isolated from the fungus Chaetomium globosum and Aspergillus flavus.
Synonyms:exact_synonym: 6,8-dihydroxy-3-{[(2R,6S)-6-methyltetrahydro-2H-pyran-2-yl]methyl}-3,4-dihydro-1H-isochromen-1-one
 related_synonym: 3,4-dihydro-6,8-dihydroxy-3-(tetrahydro-6-methyl-H-pyran-2-yl)methylisocoumarin;   Formula=C16H20O5;   InChI=1S/C16H20O5/c1-9-3-2-4-12(20-9)8-13-6-10-5-11(17)7-14(18)15(10)16(19)21-13/h5,7,9,12-13,17-18H,2-4,6,8H2,1H3/t9-,12+,13?/m0/s1;   InChIKey=WOMKDMUZNBFXKG-XAWKZAOJSA-N;   SMILES=[H][C@@]1(CCC[C@H](C)O1)CC1Cc2cc(O)cc(O)c2C(=O)O1;   cladosporin
 xref: CAS:35818-31-6;   Chemspider:34206
 xref_mesh: MESH:C000488
 xref: PMID:17125234;   PMID:22663064;   PMID:22704625;   PMID:23413753;   PMID:4629903;   PMID:5169000;   Reaxys:5086911


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asperentin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcf1 ATP binding cassette subfamily F member 1 increases expression ISO cladosporin results in increased expression of ABCF1 mRNA CTD PMID:19818335 NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 increases expression ISO cladosporin results in increased expression of AIMP1 mRNA CTD PMID:19818335 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO cladosporin results in increased expression of BLVRB mRNA CTD PMID:21356202 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression ISO cladosporin results in increased expression of CCL12 mRNA CTD PMID:21356202 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO cladosporin results in increased expression of CCL19 mRNA CTD PMID:19818335 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
decreases expression
ISO cladosporin results in increased expression of CCL20 mRNA
cladosporin results in decreased expression of CCL20 mRNA
CTD PMID:19818335 PMID:21356202 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl25 C-C motif chemokine ligand 25 increases expression ISO cladosporin results in increased expression of CCL25 mRNA CTD PMID:19818335 NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO cladosporin results in decreased expression of CCL3 mRNA CTD PMID:19818335 PMID:21356202 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO cladosporin results in decreased expression of CCL4 mRNA CTD PMID:19818335 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO cladosporin results in decreased expression of CCL7 mRNA CTD PMID:19818335 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO cladosporin results in increased expression of CCR1 mRNA CTD PMID:19818335 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr10 C-C motif chemokine receptor 10 increases expression ISO cladosporin results in increased expression of CCR10 mRNA CTD PMID:19818335 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO cladosporin results in increased expression of CCR2 mRNA CTD PMID:19818335 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 increases expression ISO cladosporin results in increased expression of CCR3 mRNA CTD PMID:19818335 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 increases expression ISO cladosporin results in increased expression of CCR4 mRNA CTD PMID:19818335 NCBI chr 8:114,176,256...114,182,155
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 increases expression ISO cladosporin results in increased expression of CCR6 mRNA CTD PMID:19818335 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 increases expression ISO cladosporin results in increased expression of CCR7 mRNA CTD PMID:19818335 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 increases expression ISO cladosporin results in increased expression of CCR9 mRNA CTD PMID:19818335 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969
JBrowse link
G Cd40lg CD40 ligand increases expression ISO cladosporin results in increased expression of CD40LG mRNA CTD PMID:19818335 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO cladosporin results in increased expression of CX3CL1 mRNA CTD PMID:19818335 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression
increases expression
ISO cladosporin results in decreased expression of CXCL10 mRNA
cladosporin results in increased expression of CXCL10 protein
CTD PMID:19818335 PMID:21356202 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 decreases expression ISO cladosporin results in decreased expression of CXCL11 mRNA CTD PMID:19818335 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO cladosporin results in increased expression of CXCL12 mRNA CTD PMID:19818335 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO cladosporin results in increased expression of CXCL13 mRNA CTD PMID:19818335 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO cladosporin results in increased expression of CXCL2 mRNA; cladosporin results in increased expression of CXCL2 protein CTD PMID:19818335 PMID:21356202 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
increases expression
ISO cladosporin results in decreased expression of CXCL1 mRNA
cladosporin results in increased expression of CXCL1 mRNA
CTD PMID:19818335 PMID:21356202 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 decreases expression
increases expression
ISO cladosporin results in decreased expression of CXCR2 mRNA
cladosporin results in increased expression of CXCR2 mRNA
CTD PMID:19818335 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression ISO cladosporin results in increased expression of CXCR3 mRNA CTD PMID:19818335 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 increases expression ISO cladosporin results in increased expression of CXCR5 mRNA CTD PMID:19818335 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893
JBrowse link
G Ifng interferon gamma increases expression ISO cladosporin results in increased expression of IFNG mRNA CTD PMID:19818335 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 increases expression ISO cladosporin results in increased expression of IL10 mRNA CTD PMID:19818335 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO cladosporin results in increased expression of IL10RA mRNA CTD PMID:19818335 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
JBrowse link
G Il10rb interleukin 10 receptor subunit beta increases expression ISO cladosporin results in increased expression of IL10RB mRNA CTD PMID:19818335 NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074
JBrowse link
G Il15 interleukin 15 increases expression ISO cladosporin results in increased expression of IL15 mRNA CTD PMID:19818335 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il16 interleukin 16 increases expression ISO cladosporin results in increased expression of IL16 mRNA CTD PMID:19818335 NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
JBrowse link
G Il18 interleukin 18 increases expression ISO cladosporin results in increased expression of IL18 mRNA CTD PMID:19818335 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression
ISO cladosporin results in increased expression of IL1B mRNA
cladosporin results in decreased expression of IL1B mRNA
CTD PMID:19818335 PMID:21356202 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression ISO cladosporin results in increased expression of IL1R1 mRNA CTD PMID:19818335 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il2rb interleukin 2 receptor subunit beta increases expression ISO cladosporin results in increased expression of IL2RB mRNA CTD PMID:19818335 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
JBrowse link
G Il4 interleukin 4 increases expression ISO cladosporin results in increased expression of IL4 mRNA CTD PMID:19818335 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5ra interleukin 5 receptor subunit alpha increases expression ISO cladosporin results in increased expression of IL5RA mRNA CTD PMID:19818335 NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544
JBrowse link
G Il6 interleukin 6 increases expression ISO cladosporin results in increased expression of IL6 mRNA CTD PMID:21356202 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO cladosporin results in increased expression of IL6RA mRNA CTD PMID:19818335 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer decreases expression ISO cladosporin results in decreased expression of IL6ST mRNA CTD PMID:19818335 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO cladosporin results in increased expression of ITGAM mRNA CTD PMID:19818335 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Lta lymphotoxin alpha increases expression ISO cladosporin results in increased expression of LTA mRNA CTD PMID:19818335 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Ltb lymphotoxin beta increases expression ISO cladosporin results in increased expression of LTB mRNA CTD PMID:19818335 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO cladosporin results in increased expression of MIF mRNA CTD PMID:19818335 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO cladosporin results in increased expression of SPP1 mRNA CTD PMID:19818335 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases expression
ISO cladosporin results in decreased expression of TNF mRNA
cladosporin results in increased expression of TNF mRNA
CTD PMID:19818335 PMID:21356202 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO cladosporin results in increased expression of TNFRSF1A mRNA CTD PMID:19818335 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        antimicrobial agent 17408
          antifungal agent 15099
            asperentin 51
              5'-hydroxy-asperentin-8-O-methylether 0
              5'-hydroxyasperentin 0
              asperentin-8-methyl ether 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic ester 15884
                                        lactone 11242
                                          delta-lactone 3868
                                            isocoumarins 1350
                                              asperentin 51
                                                5'-hydroxy-asperentin-8-O-methylether 0
                                                5'-hydroxyasperentin 0
                                                asperentin-8-methyl ether 0
paths to the root