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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chaetocin
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Accession:CHEBI:68747 term browser browse the term
Definition:An organic molecular entity that has formula C30H40N6O6S4.
Synonyms:xref_mesh: MESH:C002511


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chaetocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[chaetocin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of MAPK1 protein]; [chaetocin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of MAPK1 protein CTD PMID:26748310 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[chaetocin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of MAPK3 protein]; [chaetocin co-treated with 1-Methyl-3-isobutylxanthine] results in increased phosphorylation of MAPK3 protein CTD PMID:26748310 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mitf melanocyte inducing transcription factor multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [chaetocin inhibits the reaction [1-Methyl-3-isobutylxanthine results in increased expression of MITF protein]]; chaetocin inhibits the reaction [1-Methyl-3-isobutylxanthine results in increased expression of MITF protein] CTD PMID:26748310 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO chaetocin results in increased expression of PDK4 mRNA; chaetocin results in increased expression of PDK4 protein CTD PMID:27217333 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Tyr tyrosinase multiple interactions ISO chaetocin inhibits the reaction [1-Methyl-3-isobutylxanthine results in increased activity of TYR protein]; chaetocin inhibits the reaction [1-Methyl-3-isobutylxanthine results in increased expression of and results in increased activity of TYR protein]; chaetocin inhibits the reaction [1-Methyl-3-isobutylxanthine results in increased expression of TYR mRNA] CTD PMID:26748310 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions ISO chaetocin inhibits the reaction [1-Methyl-3-isobutylxanthine results in increased expression of TYRP1 mRNA] CTD PMID:26748310 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            chaetocin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      p-block molecular entity 19672
                        carbon group molecular entity 19574
                          organic molecular entity 19563
                            chaetocin 6
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