The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
An organic heteropentacyclic compound of the class of epipolythiodioxopiperazine. Isolated from Chaetomium globosum and Farrowia seminuda, it exhibits immunosuppressive activity.
chetomin inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA]; chetomin inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 protein]
chetomin inhibits the reaction [HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]]; chetomin inhibits the reaction [HIF1A protein promotes the reaction [TNF protein results in decreased metabolism of Oxygen]] chetomin results in decreased expression of HIF1A mRNA
chetomin inhibits the reaction [aristolochic acid I results in increased expression of VEGFA protein]; chetomin inhibits the reaction [HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]]