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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chaetomugilin D
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Accession:CHEBI:68730 term browser browse the term
Definition:An azaphilone isolated from Chaetomium globosum and has been shown to exhibit inhibitory activity against the brine shrimp (Artemia salina) and Mucor miehei.
Synonyms:exact_synonym: (6aS,7aR,8R,9R,11aR,11bS)-5-chloro-7a-hydroxy-6a,8,9-trimethyl-3-[(1E,3S)-3-methylpent-1-en-1-yl]-6a,7a,8,9,11a,11b-hexahydro-6H,11H-pyrano[3',4':4,5]furo[2,3-h]isochromene-6,11-dione
 related_synonym: Formula=C23H27ClO6;   InChI=1S/C23H27ClO6/c1-6-11(2)7-8-14-9-15-16(10-28-14)17-18-21(26)29-13(4)12(3)23(18,27)30-22(17,5)20(25)19(15)24/h7-13,17-18,27H,6H2,1-5H3/b8-7+/t11-,12+,13+,17+,18-,22-,23+/m0/s1;   InChIKey=VFAOIGZBHFMFIU-XSKLMDGHSA-N;   SMILES=CC[C@H](C)\\C=C\\C1=CC2=C(Cl)C(=O)[C@@]3(C)O[C@@]4(O)[C@@H]([C@H]3C2=CO1)C(=O)O[C@H](C)[C@H]4C
 xref: Chemspider:24705878
 xref_mesh: MESH:C539431
 xref: PMID:19246197;   Reaxys:19646845



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chaetomugilin D term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor multiple interactions ISO chaetomugilin D results in increased expression of and results in increased secretion of TNF protein CTD PMID:28535995 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    chemical entity 20055
      molecular entity 20054
        polyatomic entity 19984
          heteroatomic molecular entity 19921
            halide 18488
              organohalogen compound 18308
                organochlorine compound 18089
                  chaetomugilin D 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic group 18961
                              organic divalent group 18947
                                organodiyl group 18947
                                  carbonyl group 18900
                                    carbonyl compound 18900
                                      carboxylic ester 15933
                                        lactone 11283
                                          delta-lactone 3887
                                            chaetomugilin D 1
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