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ONTOLOGY REPORT - ANNOTATIONS


Term:methylene blue
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Accession:CHEBI:6872 term browser browse the term
Definition:An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties.
Synonyms:exact_synonym: 3,7-bis(dimethylamino)phenothiazin-5-ium chloride
 related_synonym: Basic Blue 9;   C.I. 52015;   Formula=C16H18N3S.Cl;   InChI=1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1;   InChIKey=CXKWCBBOMKCUKX-UHFFFAOYSA-M;   Methylenblau;   Methylene Blue anhydrous;   SMILES=[Cl-].CN(C)c1ccc2nc3ccc(cc3[s+]c2c1)N(C)C;   Solvent blue 8;   Swiss blue;   azul de metileno;   bleu de methylene;   chlorure de methylthioninium;   cloruro de metiltioninio;   methylthioninii chloridum;   methylthioninium chloride
 xref: Beilstein:3599847;   CAS:61-73-4;   KEGG:C00220
 xref_mesh: MESH:D008751
 xref: PMID:11145393;   PMID:11246319;   PMID:11287762;   PMID:11376884;   PMID:11427637;   PMID:12068762;   PMID:12830064;   PMID:12845393;   PMID:15120287;   PMID:16054909;   PMID:16380099;   PMID:16464752;   PMID:17499345;   PMID:17597293;   PMID:17645185;   PMID:17692516;   PMID:17721552;   PMID:17826794;   PMID:17941276;   PMID:18873190;   PMID:18980251;   PMID:19189650;   PMID:19193212;   PMID:19212058;   PMID:19277479;   PMID:19562136;   PMID:19596056;   PMID:19746714;   PMID:24788930;   PMID:25150147;   PMID:25285998;   PMID:25356528;   PMID:25440279;   PMID:25441767;   PMID:25499271;   PMID:25613051;   PMID:25679473;   PMID:25687361;   PMID:25707443;   PMID:25791029;   PMID:25913699;   PMID:26165999;   PMID:26192785;   PMID:26213475;   PMID:26221301;   PMID:26310944;   PMID:26463954;   PMID:26572462;   Reaxys:3599847;   Wikipedia:Methylene_blue


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methylene blue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Glrx glutaredoxin JBrowse link 2 2,606,032 2,615,944 RGD:6480464
G Glrx2 glutaredoxin 2 JBrowse link 13 60,529,057 60,552,115 RGD:6480464
G Gnrh1 gonadotropin releasing hormone 1 JBrowse link 15 44,441,856 44,446,064 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Maob monoamine oxidase B JBrowse link X 6,430,694 6,533,520 RGD:6480464
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:6480464
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:6480464
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:6480464
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:6480464
G Txn2 thioredoxin 2 JBrowse link 7 119,144,350 119,158,173 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:6480464
G Txnrd2 thioredoxin reductase 2 JBrowse link 11 86,667,994 86,716,063 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      chemical role 19269
        antioxidant 14224
          methylene blue 32
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      halogen 18021
                        chlorine atom 17809
                          chlorine molecular entity 17809
                            elemental chlorine 8386
                              monoatomic chlorine 8367
                                chloride 8367
                                  chloride salt 8367
                                    organic chloride salt 664
                                      methylene blue 32
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.