The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by methoxy and hydroxy groups respectively. The major pungent component in ginger.
zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of AKT2 mRNA] zingerone results in increased expression of AKT2 mRNA
zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX protein]; zingerone inhibits the reaction [Ethanol results in increased expression of BAX protein] zingerone results in increased expression of BAX protein
zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2 mRNA]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2 protein]; zingerone inhibits the reaction [Ethanol results in decreased expression of BCL2 protein] zingerone results in decreased expression of BCL2 protein zingerone results in increased expression of BCL2 mRNA
zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CASP3 mRNA]; zingerone inhibits the reaction [Ethanol results in increased expression of CASP3 protein]
zingerone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of CAT protein]
zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CYP2E1 protein]; zingerone inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]
zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of FOXO1 mRNA] zingerone results in increased expression of FOXO1 mRNA
zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL1B mRNA] zingerone results in decreased expression of IL1B mRNA; zingerone results in decreased expression of IL1B protein
zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein] zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of IL6 protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL6 mRNA]
zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MAPK8 mRNA] zingerone results in increased expression of MAPK8 mRNA
zingerone affects the localization of NFKB1 protein zingerone results in decreased expression of NFKB1 mRNA zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NFKB1 mRNA]
zingerone results in decreased expression of NOS2 protein zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of NOS2 protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NOS2 mRNA]
zingerone results in decreased expression of PTGS2 protein zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PTGS2 protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of PTGS2 mRNA]
zingerone affects the localization of and results in increased phosphorylation of RELA protein; zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of RELA protein]
zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein] zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TNF protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TNF mRNA] zingerone results in decreased expression of TNF mRNA