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ONTOLOGY REPORT - ANNOTATIONS


Term:EC 3.4.21.6 (coagulation factor Xa) inhibitor
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Accession:CHEBI:68581 term browser browse the term
Definition:An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of coagulation factor Xa (EC 3.4.21.6).
Synonyms:related_synonym: EC 3.4.21.6 inhibitor;   EC 3.4.21.6 inhibitors;   Stuart factor inhibitor;   Stuart factor inhibitors;   activated Stuart-Prower factor inhibitor;   activated Stuart-Prower factor inhibitors;   activated blood-coagulation factor X inhibitor;   activated blood-coagulation factor X inhibitors;   activated factor X inhibitor;   activated factor X inhibitors;   autoprothrombin C inhibitor;   autoprothrombin C inhibitors;   coagulation factor Xa (EC 3.4.21.6) inhibitors;   coagulation factor Xa inhibitor;   coagulation factor Xa inhibitors;   factor Xa inhibitor;   factor Xa inhibitors;   plasma thromboplastin inhibitor;   plasma thromboplastin inhibitors;   prothrombase inhibitor;   prothrombase inhibitors;   prothrombinase inhibitor;   prothrombinase inhibitors;   thrombokinase inhibitor;   thrombokinase inhibitors;   thromboplastin inhibitor;   thromboplastin inhibitors
 xref: Wikipedia:Factor_Xa_inhibitor


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rivaroxaban term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        biochemical role 19125
          enzyme inhibitor 17962
            EC 3.* (hydrolase) inhibitor 17493
              EC 3.4.* (hydrolases acting on peptide bond) inhibitor 3125
                EC 3.4.21.* (serine endopeptidase) inhibitor 1555
                  EC 3.4.21.6 (coagulation factor Xa) inhibitor 1
                    apixaban 0
                    betrixaban 0
                    edoxaban 0
                    edoxaban tosylate + 0
                    edoxaban tosylate hydrate 0
                    eribaxaban 0
                    rivaroxaban 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.