Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:rivaroxaban
go back to main search page
Accession:CHEBI:68579 term browser browse the term
Definition:A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery.
Synonyms:exact_synonym: 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide
 related_synonym: BAY 59-7939;   BAY59-7939;   Formula=C19H18ClN3O5S;   InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1;   InChIKey=KGFYHTZWPPHNLQ-AWEZNQCLSA-N;   SMILES=O1CC(N(CC1)C2=CC=C(C=C2)N3C[C@@H](OC3=O)CNC(C=4SC(=CC4)Cl)=O)=O;   Xarelto
 xref: CAS:366789-02-8;   DrugBank:DB06228;   Drug_Central:4182;   KEGG:D07086;   LINCS:LSM-5499
 xref_mesh: MESH:D000069552
 xref: PDBeChem:RIV;   PMCID:PMC7292653;   PMID:22042412;   PMID:22173426;   PMID:22187012;   PMID:22242932;   PMID:22272729;   PMID:22372178;   PMID:22387577;   PMID:22422332;   PMID:22533680;   PMID:22534269;   PMID:22534775;   PMID:22542983;   PMID:22651881;   PMID:22664783;   PMID:22701330;   PMID:22740145;   PMID:22777255;   PMID:22800431;   PMID:22811404;   PMID:22871192;   PMID:22884545;   PMID:22932305;   PMID:22958812;   PMID:23006523;   PMID:23014816;   PMID:30653475;   PMID:31784708;   PMID:32002769;   PMID:32023227;   PMID:32223113;   PMID:32223511;   PMID:32252075;   PMID:32265542;   PMID:32279215;   PMID:32296145;   PMID:32382756;   PMID:32519800;   PMID:32548552;   PMID:32548556;   Patent:EP1685841;   Patent:US2005182055;   Patent:US2007026065;   Patent:US2009036504;   Patent:US2010151011;   Patent:US2011034453;   Patent:US2011112083;   Patent:US2011152266;   Patent:US2011288294;   Patent:US7816355;   Patent:WO2004060887;   Patent:WO2005068456;   Patent:WO2008140220;   Patent:WO2011080341;   Patent:WO2012035057;   Patent:WO2012051692;   Reaxys:10206739;   Wikipedia:Rivaroxaban


show annotations for term's descendants       view all columns           Sort by:
 
rivaroxaban term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    role 19727
      application 19373
        pharmaceutical 19243
          drug 19243
            hematologic agent 4360
              anticoagulant 4154
                rivaroxaban 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      carbon group element atom 19559
                        carbon atom 19548
                          organic molecular entity 19548
                            organic group 18463
                              organic divalent group 18456
                                organodiyl group 18456
                                  carbonyl group 18356
                                    carbonyl compound 18356
                                      carboxylic acid 18027
                                        carboacyl group 17185
                                          univalent carboacyl group 17185
                                            carbamoyl group 16924
                                              carboxamide 16924
                                                lactam 7828
                                                  rivaroxaban 8
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.