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ONTOLOGY REPORT - ANNOTATIONS


Term:teriflunomide
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Accession:CHEBI:68540 term browser browse the term
Definition:An enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis.
Synonyms:exact_synonym: (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
 related_synonym: (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide;   A 77-1726;   A 771726;   Aubagio;   Formula=C12H9F3N2O2;   HMR 1726;   HMR1726;   InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-;   InChIKey=UTNUDOFZCWSZMS-YFHOEESVSA-N;   SMILES=C\\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)C(F)(F)F;   teriflunomida;   teriflunomidum
 alt_id: MESH:C072876
 xref: CAS:163451-81-8 "ChemIDplus";   CAS:163451-81-8 "KEGG DRUG";   Drug_Central:4634 "DrugCentral";   KEGG:D10172
 xref_mesh: MESH:C072876
 xref: PDBeChem:A26;   PMID:20880295 "Europe PMC";   PMID:21349677 "Europe PMC";   PMID:21367665 "Europe PMC";   PMID:21425264 "Europe PMC";   PMID:21625416 "Europe PMC";   PMID:21991951 "Europe PMC";   PMID:22012334 "Europe PMC";   PMID:22052286 "Europe PMC";   PMID:22052362 "Europe PMC";   PMID:22148963 "Europe PMC";   PMID:22229697 "Europe PMC";   PMID:22278631 "Europe PMC";   PMID:22307384 "Europe PMC";   PMID:22398660 "Europe PMC";   PMID:22426573 "Europe PMC";   PMID:22612746 "Europe PMC";   PMID:22622860 "Europe PMC";   PMID:22673950 "Europe PMC";   PMID:22723573 "Europe PMC";   PMID:22766059 "Europe PMC";   PMID:22784880 "Europe PMC";   PMID:22796174 "Europe PMC";   PMID:22960763 "Europe PMC";   PMID:22965070 "Europe PMC";   Reaxys:6655982 "Reaxys";   Wikipedia:Teriflunomide


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Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      biological role 0
        aetiopathogenetic role 0
          hepatotoxic agent 0
            teriflunomide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            organic group 0
                              organic divalent group 0
                                organodiyl group 0
                                  carbonyl group 0
                                    carbonyl compound 0
                                      carboxylic acid 0
                                        carboacyl group 0
                                          univalent carboacyl group 0
                                            carbamoyl group 0
                                              carboxamide 0
                                                alpha,beta-unsaturated carboxylic acid amide 0
                                                  enamide 0
                                                    teriflunomide 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.