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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glutathione depleting agent
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Accession:CHEBI:68509 term browser browse the term
Definition:A compound which causes a reduction in the levels of glutathione in cells.
Synonyms:related_synonym: glutathione depleting agents;   glutathione depletion agent;   glutathione depletion agents;   glutathione depletor;   glutathione depletors


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diethyl maleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO diethyl maleate results in increased expression of ABCC2 mRNA CTD PMID:25270620 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO diethyl maleate results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO diethyl maleate results in decreased expression of ACACA mRNA CTD PMID:25270620 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions EXP diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]] CTD PMID:17134953 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acy3 aminoacylase 3 decreases expression EXP diethyl maleate results in decreased expression of ACY3 mRNA CTD PMID:21161181 NCBI chr 1:201,279,751...201,285,803
Ensembl chr 1:201,279,851...201,283,175
JBrowse link
G Adm adrenomedullin increases expression ISO diethyl maleate results in increased expression of ADM mRNA CTD PMID:33545341 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adora3 adenosine A3 receptor decreases expression EXP diethyl maleate results in decreased expression of ADORA3 mRNA CTD PMID:21161181
G Aen apoptosis enhancing nuclease increases expression ISO diethyl maleate results in increased expression of AEN mRNA CTD PMID:33545341 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Afp alpha-fetoprotein increases expression ISO diethyl maleate results in increased expression of AFP mRNA CTD PMID:25270620 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 increases expression ISO diethyl maleate results in increased expression of AHCYL1 mRNA CTD PMID:25270620 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression EXP diethyl maleate results in increased expression of AKR1A1 protein CTD PMID:21161181 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO diethyl maleate results in increased expression of AKR1B10 mRNA CTD PMID:33545341 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO diethyl maleate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects reduction ISO diethyl maleate affects the reduction of ALDH1A1 protein CTD PMID:19843705 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP diethyl maleate results in decreased expression of ALDH1B1 mRNA CTD PMID:21161181 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases reduction
increases expression
decreases expression
ISO
EXP
diethyl maleate results in decreased reduction of ALDH2 protein
diethyl maleate results in increased expression of ALDH2 protein
diethyl maleate results in decreased expression of ALDH2 protein
CTD PMID:19843705 PMID:21161181 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression EXP diethyl maleate results in decreased expression of ALDOB protein CTD PMID:21161181 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression EXP diethyl maleate results in decreased expression of AMIGO2 mRNA CTD PMID:21161181 NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression EXP diethyl maleate results in decreased expression of ANGPTL2 mRNA CTD PMID:21161181 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO diethyl maleate results in increased expression of ANGPTL4 mRNA CTD PMID:33545341 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ankrd46 ankyrin repeat domain 46 decreases expression EXP diethyl maleate results in decreased expression of ANKRD46 mRNA CTD PMID:21161181 NCBI chr 7:67,647,202...67,668,180
Ensembl chr 7:67,647,204...67,668,132
JBrowse link
G Anln anillin, actin binding protein increases expression EXP diethyl maleate results in increased expression of ANLN mRNA CTD PMID:21161181 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G Anxa3 annexin A3 decreases expression EXP diethyl maleate results in decreased expression of ANXA3 mRNA CTD PMID:21161181 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Ap3m2 adaptor related protein complex 3 subunit mu 2 decreases expression EXP diethyl maleate results in decreased expression of AP3M2 mRNA CTD PMID:21161181 NCBI chr16:69,217,526...69,237,372
Ensembl chr16:69,217,633...69,235,431
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO diethyl maleate results in increased expression of APAF1 mRNA CTD PMID:11875189 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Aplp1 amyloid beta precursor like protein 1 decreases expression ISO diethyl maleate results in decreased expression of APLP1 mRNA CTD PMID:25270620 NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155
JBrowse link
G Apol9a apolipoprotein L 9a decreases expression EXP diethyl maleate results in decreased expression of APOL9A mRNA CTD PMID:21161181 NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 increases expression ISO diethyl maleate results in increased expression of ARHGAP9 mRNA CTD PMID:33545341 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
JBrowse link
G Arrdc2 arrestin domain containing 2 decreases expression EXP diethyl maleate results in decreased expression of ARRDC2 mRNA CTD PMID:21161181 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029
JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO diethyl maleate results in decreased expression of ARRDC4 mRNA CTD PMID:25270620 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone increases expression EXP diethyl maleate results in increased expression of ASF1B mRNA CTD PMID:21161181 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 decreases expression ISO diethyl maleate results in decreased expression of ASXL1 mRNA CTD PMID:25270620 NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO diethyl maleate results in increased expression of ATM mRNA CTD PMID:11875189 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression EXP diethyl maleate results in increased expression of ATP5F1B protein CTD PMID:21161181 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Aurka aurora kinase A increases expression
decreases expression
EXP
ISO
diethyl maleate results in increased expression of AURKA mRNA
diethyl maleate results in decreased expression of AURKA mRNA
CTD PMID:21161181 PMID:25270620 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO diethyl maleate results in increased expression of BBC3 mRNA CTD PMID:33545341 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO [diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of BCL2 mRNA
diethyl maleate results in increased expression of BCL2 mRNA
CTD PMID:22564015 PMID:33545341 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression EXP diethyl maleate results in decreased expression of BCL2A1 mRNA CTD PMID:21161181 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl3 BCL3, transcription coactivator decreases expression ISO diethyl maleate results in decreased expression of BCL3 mRNA CTD PMID:25270620 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bcl6b BCL6B, transcription repressor decreases expression EXP diethyl maleate results in decreased expression of BCL6B mRNA CTD PMID:21161181 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 decreases expression EXP diethyl maleate results in decreased expression of BHLHE41 mRNA CTD PMID:21161181 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP diethyl maleate results in decreased expression of BHMT mRNA CTD PMID:21161181 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA] CTD PMID:12774022 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO diethyl maleate results in increased expression of BLVRB mRNA CTD PMID:25270620 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
JBrowse link
G Bmf Bcl2 modifying factor decreases expression EXP diethyl maleate results in decreased expression of BMF mRNA CTD PMID:21161181 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Brip1 BRCA1 interacting helicase 1 increases expression EXP diethyl maleate results in increased expression of BRIP1 mRNA CTD PMID:21161181 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Btbd2 BTB domain containing 2 decreases expression EXP diethyl maleate results in decreased expression of BTBD2 mRNA CTD PMID:21161181 NCBI chr 7:9,058,609...9,075,341
Ensembl chr 7:9,060,788...9,075,344
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression
decreases expression
multiple interactions
ISO diethyl maleate results in increased expression of BTG2 mRNA
diethyl maleate results in decreased expression of BTG2 mRNA
NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]
CTD PMID:22003191 PMID:25270620 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C6 complement C6 decreases expression EXP diethyl maleate results in decreased expression of C6 mRNA CTD PMID:21161181 NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
G Casp2 caspase 2 increases expression ISO diethyl maleate results in increased expression of CASP2 mRNA CTD PMID:11875189 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
ISO diethyl maleate results in increased expression of CASP3 mRNA
diethyl maleate results in increased cleavage of CASP3 protein
CTD PMID:11875189 PMID:21105742 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases expression ISO diethyl maleate results in increased expression of CASP9 mRNA CTD PMID:11875189 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases expression EXP diethyl maleate results in decreased expression of CAT protein CTD PMID:21161181 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression ISO diethyl maleate results in increased expression of CBR1 mRNA CTD PMID:25270620 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression
multiple interactions
ISO diethyl maleate results in increased expression of CBR3 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diethyl maleate results in increased expression of CBR3 mRNA]
CTD PMID:20806931 PMID:25270620 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Cbx4 chromobox 4 increases expression ISO diethyl maleate results in increased expression of CBX4 mRNA CTD PMID:33545341 NCBI chr10:104,337,140...104,343,210 JBrowse link
G Ccdc50 coiled-coil domain containing 50 decreases expression ISO diethyl maleate results in decreased expression of CCDC50 mRNA CTD PMID:25270620 NCBI chr11:73,332,798...73,395,333
Ensembl chr11:73,334,248...73,395,150
JBrowse link
G Ccna1 cyclin A1 decreases expression ISO diethyl maleate results in decreased expression of CCNA1 mRNA CTD PMID:11875189 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccna2 cyclin A2 increases expression EXP diethyl maleate results in increased expression of CCNA2 mRNA CTD PMID:21161181 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression
ISO
EXP
diethyl maleate results in decreased expression of CCND1 mRNA
diethyl maleate results in increased expression of CCND1 mRNA
CTD PMID:11875189 PMID:21161181 PMID:25270620 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne2 cyclin E2 increases expression EXP diethyl maleate results in increased expression of CCNE2 mRNA CTD PMID:21161181 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccnk cyclin K decreases expression ISO diethyl maleate results in decreased expression of CCNK mRNA CTD PMID:11875189 NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
JBrowse link
G Cd80 Cd80 molecule multiple interactions
increases expression
ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein
diethyl maleate results in increased expression of CD80 protein
CTD PMID:31958493 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule multiple interactions
increases expression
ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; bisindolylmaleimide I inhibits the reaction [diethyl maleate results in increased expression of CD86 protein] CTD PMID:24136171 PMID:31958493 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc25a cell division cycle 25A increases expression EXP diethyl maleate results in increased expression of CDC25A mRNA CTD PMID:21161181 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdca2 cell division cycle associated 2 increases expression EXP diethyl maleate results in increased expression of CDCA2 mRNA CTD PMID:21161181 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression EXP diethyl maleate results in increased expression of CDCA3 mRNA CTD PMID:21161181 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
JBrowse link
G Cdca8 cell division cycle associated 8 increases expression EXP diethyl maleate results in increased expression of CDCA8 mRNA CTD PMID:21161181 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
JBrowse link
G Cdh11 cadherin 11 decreases expression EXP diethyl maleate results in decreased expression of CDH11 mRNA CTD PMID:21161181 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO diethyl maleate results in increased expression of CDKN1A mRNA; diethyl maleate results in increased expression of CDKN1A protein
TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]
CTD PMID:11875189 PMID:27982581 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cds2 CDP-diacylglycerol synthase 2 increases expression ISO diethyl maleate results in increased expression of CDS2 mRNA CTD PMID:25270620 NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541
JBrowse link
G Ces1d carboxylesterase 1D decreases expression
increases reduction
EXP
ISO
diethyl maleate results in decreased expression of CES1D protein
diethyl maleate results in increased reduction of CES1D protein
CTD PMID:19843705 PMID:21161181 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression EXP diethyl maleate results in decreased expression of CFLAR mRNA CTD PMID:21161181 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit increases expression ISO diethyl maleate results in increased expression of CHRNA4 mRNA CTD PMID:33545341 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Cidec cell death-inducing DFFA-like effector c decreases expression EXP diethyl maleate results in decreased expression of CIDEC mRNA CTD PMID:21161181 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP diethyl maleate results in decreased expression of CITED2 mRNA CTD PMID:21161181 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression EXP diethyl maleate results in decreased expression of CITED4 mRNA CTD PMID:21161181 NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135
JBrowse link
G Ckb creatine kinase B decreases reduction ISO diethyl maleate results in decreased reduction of CKB protein CTD PMID:19843705 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO diethyl maleate results in increased expression of CKS2 mRNA CTD PMID:33545341 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clk1 CDC-like kinase 1 increases expression ISO diethyl maleate results in increased expression of CLK1 mRNA CTD PMID:33545341 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression EXP diethyl maleate results in decreased expression of CMPK2 mRNA CTD PMID:21161181 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
JBrowse link
G Cntn1 contactin 1 increases expression ISO diethyl maleate results in increased expression of CNTN1 mRNA CTD PMID:33545341 NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP diethyl maleate results in decreased expression of COL1A1 mRNA CTD PMID:21161181 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO diethyl maleate results in decreased expression of COL3A1 mRNA CTD PMID:25270620 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Commd3 COMM domain containing 3 increases expression ISO diethyl maleate results in increased expression of COMMD3 mRNA CTD PMID:25270620 NCBI chr17:81,327,451...81,331,183
Ensembl chr17:81,327,405...81,331,177
JBrowse link
G Comt catechol-O-methyltransferase decreases expression EXP diethyl maleate results in decreased expression of COMT mRNA CTD PMID:21161181 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cp ceruloplasmin decreases expression ISO diethyl maleate results in decreased expression of CP mRNA CTD PMID:25270620 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cpsf4l cleavage and polyadenylation specific factor 4-like increases expression ISO diethyl maleate results in increased expression of CPSF4L mRNA CTD PMID:33545341 NCBI chr10:98,741,816...98,756,069 JBrowse link
G Crym crystallin, mu decreases expression EXP diethyl maleate results in decreased expression of CRYM mRNA CTD PMID:21161181 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP diethyl maleate results in decreased expression of CSRP1 mRNA CTD PMID:21161181 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 decreases reduction ISO diethyl maleate results in decreased reduction of CSRP3 protein CTD PMID:19843705 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression EXP diethyl maleate results in decreased expression of CXCL10 mRNA CTD PMID:21161181 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP diethyl maleate results in decreased expression of CXCL12 mRNA CTD PMID:21161181 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression EXP diethyl maleate results in decreased expression of CXCL9 mRNA CTD PMID:21161181 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cyb5a cytochrome b5 type A increases expression ISO diethyl maleate results in increased expression of CYB5A mRNA CTD PMID:25270620 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression EXP diethyl maleate results in decreased expression of CYP26B1 mRNA CTD PMID:21161181 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression EXP diethyl maleate results in decreased expression of DBP mRNA CTD PMID:21161181 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO diethyl maleate results in increased expression of DDIT3 mRNA CTD PMID:33545341 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO diethyl maleate results in increased expression of DDIT4 mRNA CTD PMID:33545341 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression ISO diethyl maleate results in increased expression of DDIT4L mRNA CTD PMID:25270620 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
JBrowse link
G Dhx58 DEXH-box helicase 58 decreases expression EXP diethyl maleate results in decreased expression of DHX58 mRNA CTD PMID:21161181 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO diethyl maleate results in increased expression of DNAJB1 mRNA CTD PMID:33545341 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO diethyl maleate results in increased expression of DNAJB4 mRNA CTD PMID:33545341 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dnmbp dynamin binding protein decreases expression EXP diethyl maleate results in decreased expression of DNMBP mRNA CTD PMID:21161181 NCBI chr 1:242,736,189...242,829,498
Ensembl chr 1:242,736,189...242,802,604
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases reduction ISO diethyl maleate results in decreased reduction of DPYSL2 protein CTD PMID:19843705 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L decreases expression EXP diethyl maleate results in decreased expression of DTX3L mRNA CTD PMID:21161181 NCBI chr11:64,814,926...64,824,538
Ensembl chr11:64,814,926...64,824,538
JBrowse link
G Dus3l dihydrouridine synthase 3-like decreases expression ISO diethyl maleate results in decreased expression of DUS3L mRNA CTD PMID:25270620 NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO diethyl maleate results in increased expression of DUSP6 mRNA CTD PMID:33545341 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression EXP diethyl maleate results in decreased expression of EEF2K mRNA CTD PMID:21161181 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 decreases expression EXP diethyl maleate results in decreased expression of EIF2AK2 mRNA CTD PMID:21161181 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression ISO diethyl maleate results in increased expression of ENTPD5 mRNA CTD PMID:25270620 NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530
JBrowse link
G Eras ES cell expressed Ras decreases expression ISO diethyl maleate results in decreased expression of ERAS mRNA CTD PMID:25270620 NCBI chr  X:14,573,987...14,578,455
Ensembl chr  X:14,573,987...14,578,374
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase increases expression EXP diethyl maleate results in increased expression of ERCC6L mRNA CTD PMID:21161181 NCBI chr  X:67,245,414...67,261,222
Ensembl chr  X:67,245,414...67,280,756
JBrowse link
G Exo1 exonuclease 1 increases expression EXP diethyl maleate results in increased expression of EXO1 mRNA CTD PMID:21161181 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression EXP diethyl maleate results in increased expression of FABP1 protein CTD PMID:21161181 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp7 fatty acid binding protein 7 decreases expression EXP diethyl maleate results in decreased expression of FABP7 mRNA CTD PMID:21161181 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
JBrowse link
G Fam126b family with sequence similarity 126, member B decreases expression EXP diethyl maleate results in decreased expression of FAM126B mRNA CTD PMID:21161181 NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
JBrowse link
G Fam83d family with sequence similarity 83, member D increases expression ISO diethyl maleate results in increased expression of FAM83D mRNA CTD PMID:33545341 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Fasn fatty acid synthase decreases expression EXP diethyl maleate results in decreased expression of FASN mRNA CTD PMID:21161181 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbn1 fibrillin 1 decreases expression EXP diethyl maleate results in decreased expression of FBN1 mRNA CTD PMID:21161181 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases expression EXP diethyl maleate results in decreased expression of FBP1 protein CTD PMID:21161181 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fgf17 fibroblast growth factor 17 decreases expression ISO diethyl maleate results in decreased expression of FGF17 mRNA CTD PMID:25270620 NCBI chr15:45,711,901...45,717,063
Ensembl chr15:45,711,998...45,717,063
JBrowse link
G Fgg fibrinogen gamma chain decreases expression ISO diethyl maleate results in decreased expression of FGG mRNA CTD PMID:25270620 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases expression EXP diethyl maleate results in decreased expression of FGR mRNA CTD PMID:21161181 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
JBrowse link
G Fndc3b fibronectin type III domain containing 3B decreases expression ISO diethyl maleate results in decreased expression of FNDC3B mRNA CTD PMID:25270620 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO diethyl maleate results in increased expression of FOS mRNA CTD PMID:10915739 PMID:33545341 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxo3 forkhead box O3 increases expression ISO diethyl maleate results in increased expression of FOXO3 mRNA CTD PMID:33545341 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Fstl3 follistatin like 3 increases expression ISO diethyl maleate results in increased expression of FSTL3 mRNA CTD PMID:33545341 NCBI chr 7:9,924,670...9,929,195
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO diethyl maleate results in decreased expression of G6PC mRNA CTD PMID:25270620 NCBI chr10:86,307,400...86,318,766 JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity
increases expression
EXP
ISO
diethyl maleate results in increased activity of G6PD protein
diethyl maleate results in increased expression of G6PD mRNA
CTD PMID:3099627 PMID:33545341 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression ISO diethyl maleate results in decreased expression of GAB1 mRNA CTD PMID:25270620 NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO diethyl maleate results in increased expression of GADD45A mRNA CTD PMID:33545341 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO diethyl maleate results in increased expression of GADD45G mRNA CTD PMID:33545341 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases reduction ISO diethyl maleate results in increased reduction of GAPDH protein CTD PMID:19843705 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gba2 glucosylceramidase beta 2 decreases expression ISO diethyl maleate results in decreased expression of GBA2 mRNA CTD PMID:25270620 NCBI chr 5:57,822,389...57,834,522
Ensembl chr 5:57,822,389...57,834,072
JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression EXP diethyl maleate results in decreased expression of GBP2 mRNA CTD PMID:21161181 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases activity
increases expression
ISO
EXP
diethyl maleate results in increased activity of GCLC protein
diethyl maleate results in increased expression of GCLC mRNA; diethyl maleate results in increased expression of GCLC protein
CTD PMID:10915739 PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 More... NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP
ISO
diethyl maleate results in increased expression of GCLM mRNA; diethyl maleate results in increased expression of GCLM protein CTD PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 PMID:33545341 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO diethyl maleate results in increased expression of GCNT3 mRNA CTD PMID:33545341 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO diethyl maleate results in increased expression of GDF15 mRNA CTD PMID:33545341 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO diethyl maleate results in increased expression of GDF9 mRNA CTD PMID:33545341 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
JBrowse link
G Gfod1 glucose-fructose oxidoreductase domain containing 1 increases expression ISO diethyl maleate results in increased expression of GFOD1 mRNA CTD PMID:33545341 NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938
JBrowse link
G Glul glutamate-ammonia ligase decreases expression ISO diethyl maleate results in decreased expression of GLUL mRNA CTD PMID:25270620 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression EXP diethyl maleate results in decreased expression of GOT2 protein CTD PMID:21161181 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 decreases expression ISO diethyl maleate results in decreased expression of GPIHBP1 mRNA CTD PMID:25270620 NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression EXP diethyl maleate results in decreased expression of GRIA3 mRNA CTD PMID:21161181 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Gsn gelsolin decreases reduction ISO diethyl maleate results in decreased reduction of GSN protein CTD PMID:19843705 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO diethyl maleate results in increased expression of GSR mRNA CTD PMID:25270620 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase increases expression EXP diethyl maleate results in increased expression of GSS mRNA CTD PMID:10978506 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP diethyl maleate results in increased expression of GSTA3 protein CTD PMID:9794803 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO diethyl maleate results in increased expression of GSTA2 mRNA CTD PMID:25270620 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP diethyl maleate results in increased expression of GSTA5 protein CTD PMID:9794803 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions ISO [diethyl maleate results in decreased abundance of Glutathione] which results in decreased expression of GSTK1 mRNA CTD PMID:22564015 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP diethyl maleate results in decreased expression of GSTM1 protein CTD PMID:21161181 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression ISO diethyl maleate results in increased expression of GSTO1 mRNA CTD PMID:25270620 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP diethyl maleate results in increased expression of GSTP1 protein CTD PMID:9794803 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP diethyl maleate results in increased expression of GSTT1 protein CTD PMID:9794803 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression EXP diethyl maleate results in increased expression of GTSE1 mRNA CTD PMID:21161181 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
JBrowse link
G H2az2 H2A.Z variant histone 2 increases expression ISO diethyl maleate results in increased expression of H2AZ2 mRNA CTD PMID:33545341 NCBI chr14:81,293,299...81,312,209
Ensembl chr14:81,293,299...81,312,144
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) increases expression ISO diethyl maleate results in increased expression of H6PD mRNA CTD PMID:25270620 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression ISO diethyl maleate results in increased expression of HAMP mRNA CTD PMID:33545341 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Helb DNA helicase B decreases expression ISO diethyl maleate results in decreased expression of HELB mRNA CTD PMID:25270620 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression EXP diethyl maleate results in decreased expression of HES6 mRNA CTD PMID:21161181 NCBI chr 9:92,001,838...92,003,580
Ensembl chr 9:92,001,841...92,003,559
JBrowse link
G Hjurp Holliday junction recognition protein increases expression EXP diethyl maleate results in increased expression of HJURP mRNA CTD PMID:21161181 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO diethyl maleate results in increased expression of HMOX1 mRNA CTD PMID:20491607 PMID:25270620 PMID:33545341 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases reduction ISO diethyl maleate results in decreased reduction of HNRNPH1 protein CTD PMID:19843705 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 increases expression ISO diethyl maleate results in increased expression of HSD17B10 mRNA CTD PMID:33545341 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression EXP diethyl maleate results in decreased expression of HSD17B2 mRNA CTD PMID:21161181 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO diethyl maleate results in increased expression of HSPA1B mRNA CTD PMID:33545341 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression ISO diethyl maleate results in increased expression of HSPA1L mRNA CTD PMID:33545341 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases reduction ISO diethyl maleate results in decreased reduction of HSPA5 protein CTD PMID:19843705 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases reduction ISO diethyl maleate results in increased reduction of HSPA8 protein CTD PMID:19843705 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO diethyl maleate results in increased expression of HTATIP2 mRNA CTD PMID:25270620 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO diethyl maleate results in decreased expression of ICAM1 mRNA CTD PMID:25270620 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression ISO diethyl maleate results in decreased expression of ID3 mRNA CTD PMID:25270620 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein decreases expression ISO diethyl maleate results in decreased expression of ID4 mRNA CTD PMID:25270620 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression EXP diethyl maleate results in decreased expression of IFIT3 mRNA CTD PMID:21161181 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO diethyl maleate results in increased expression of IFRD1 mRNA CTD PMID:33545341 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO diethyl maleate results in decreased expression of IKBKE mRNA CTD PMID:25270620 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma increases expression ISO diethyl maleate results in increased expression of IKBKG mRNA CTD PMID:25270620 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il10 interleukin 10 increases secretion ISO diethyl maleate results in increased secretion of IL10 protein CTD PMID:31958493 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il18 interleukin 18 increases expression ISO diethyl maleate results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein CTD PMID:31958493 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Inhbb inhibin subunit beta B decreases expression ISO diethyl maleate results in decreased expression of INHBB mRNA CTD PMID:25270620 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP diethyl maleate results in decreased expression of INMT mRNA CTD PMID:21161181 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
JBrowse link
G Ints7 integrator complex subunit 7 decreases expression ISO diethyl maleate results in decreased expression of INTS7 mRNA CTD PMID:25270620 NCBI chr13:103,155,123...103,207,953
Ensembl chr13:103,155,090...103,208,592
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression EXP diethyl maleate results in decreased expression of IRF7 mRNA CTD PMID:21161181 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Irf9 interferon regulatory factor 9 decreases expression EXP diethyl maleate results in decreased expression of IRF9 mRNA CTD PMID:21161181 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236
JBrowse link
G Irgm immunity-related GTPase M decreases expression EXP diethyl maleate results in decreased expression of IRGM mRNA CTD PMID:21161181 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Itgal integrin subunit alpha L decreases expression EXP diethyl maleate results in decreased expression of ITGAL mRNA CTD PMID:21161181 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression ISO diethyl maleate results in decreased expression of ITIH3 mRNA CTD PMID:25270620 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 decreases expression ISO diethyl maleate results in decreased expression of ITIH4 mRNA CTD PMID:25270620 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
JBrowse link
G Jam3 junctional adhesion molecule 3 decreases expression EXP diethyl maleate results in decreased expression of JAM3 mRNA CTD PMID:21161181 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
increases phosphorylation
ISO pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]
diethyl maleate results in increased expression of JUN mRNA
CTD PMID:10915739 PMID:12774022 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 decreases expression ISO diethyl maleate results in decreased expression of KCNE3 mRNA CTD PMID:25270620 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO diethyl maleate results in increased expression of KEAP1 mRNA; diethyl maleate results in increased expression of KEAP1 protein CTD PMID:27358234 PMID:33545341 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 increases expression ISO diethyl maleate results in increased expression of KHDRBS3 mRNA CTD PMID:33545341 NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460
JBrowse link
G Kifc1 kinesin family member C1 increases expression EXP diethyl maleate results in increased expression of KIFC1 mRNA CTD PMID:21161181 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
JBrowse link
G Klf10 Kruppel-like factor 10 decreases expression EXP
ISO
diethyl maleate results in decreased expression of KLF10 mRNA CTD PMID:21161181 PMID:25270620 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Krt75 keratin 75 increases reduction ISO diethyl maleate results in increased reduction of KRT75 protein CTD PMID:19843705 NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345
JBrowse link
G Lama1 laminin subunit alpha 1 decreases expression ISO diethyl maleate results in decreased expression of LAMA1 mRNA CTD PMID:25270620 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478
JBrowse link
G Lancl2 LanC like 2 decreases expression ISO diethyl maleate results in decreased expression of LANCL2 mRNA CTD PMID:25270620 NCBI chr 4:87,441,821...87,483,707
Ensembl chr 4:87,441,823...87,482,800
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression EXP diethyl maleate results in decreased expression of LDLR mRNA CTD PMID:21161181 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lepr leptin receptor decreases expression EXP diethyl maleate results in decreased expression of LEPR mRNA CTD PMID:21161181 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgals3bp galectin 3 binding protein decreases expression EXP diethyl maleate results in decreased expression of LGALS3BP mRNA CTD PMID:21161181 NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256
JBrowse link
G Lmnb1 lamin B1 increases expression EXP diethyl maleate results in increased expression of LMNB1 mRNA CTD PMID:21161181 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G Lmo7 LIM domain 7 decreases expression EXP diethyl maleate results in decreased expression of LMO7 mRNA CTD PMID:21161181 NCBI chr15:78,567,029...78,769,833
Ensembl chr15:78,567,023...78,769,783
JBrowse link
G LOC100363405 hypothetical LOC100363405 decreases expression EXP diethyl maleate results in decreased expression of ZFP37 mRNA CTD PMID:21161181 NCBI chr 5:74,930,335...74,960,075
Ensembl chr 5:74,863,483...74,960,101
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO diethyl maleate results in increased expression of HSPA6 mRNA CTD PMID:33545341 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 decreases expression EXP diethyl maleate results in decreased expression of LRIG3 mRNA CTD PMID:21161181 NCBI chr 7:61,816,313...61,866,275
Ensembl chr 7:61,816,342...61,866,481
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 increases expression EXP diethyl maleate results in increased expression of LRRN4 mRNA CTD PMID:21161181 NCBI chr 3:120,138,093...120,150,877
Ensembl chr 3:120,139,410...120,150,831
JBrowse link
G Lrtm2 leucine-rich repeats and transmembrane domains 2 decreases expression EXP diethyl maleate results in decreased expression of LRTM2 mRNA CTD PMID:21161181 NCBI chr 4:152,485,863...152,508,248
Ensembl chr 4:152,485,866...152,500,377
JBrowse link
G Ltc4s leukotriene C4 synthase decreases expression EXP diethyl maleate results in decreased expression of LTC4S mRNA CTD PMID:21161181 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
JBrowse link
G Lum lumican decreases expression EXP diethyl maleate results in decreased expression of LUM mRNA CTD PMID:21161181 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Ly6c Ly6-C antigen decreases expression EXP diethyl maleate results in decreased expression of LY6C mRNA CTD PMID:21161181 NCBI chr 7:106,959,508...106,963,360
Ensembl chr 7:106,959,511...106,963,329
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO diethyl maleate results in increased expression of MAFF mRNA CTD PMID:20491607 PMID:33545341 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO diethyl maleate results in increased expression of MAFG mRNA CTD PMID:33545341 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Maoa monoamine oxidase A increases expression ISO diethyl maleate results in increased expression of MAOA mRNA CTD PMID:25270620 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Mapk1ip1l mitogen-activated protein kinase 1 interacting protein 1-like increases expression ISO diethyl maleate results in increased expression of MAPK1IP1L mRNA CTD PMID:33545341 NCBI chr15:20,545,028...20,567,010
Ensembl chr15:20,545,059...20,569,674
JBrowse link
G Marveld1 MARVEL domain containing 1 decreases expression EXP diethyl maleate results in decreased expression of MARVELD1 mRNA CTD PMID:21161181 NCBI chr 1:240,954,452...240,958,384
Ensembl chr 1:240,954,452...240,958,384
JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 increases expression ISO diethyl maleate results in increased expression of MBOAT7 mRNA CTD PMID:33545341 NCBI chr 1:65,525,206...65,539,538 JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor increases expression EXP diethyl maleate results in increased expression of MCM10 mRNA CTD PMID:21161181 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression EXP diethyl maleate results in increased expression of MCM4 mRNA CTD PMID:21161181 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Me1 malic enzyme 1 increases expression ISO diethyl maleate results in increased expression of ME1 mRNA CTD PMID:25270620 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression EXP diethyl maleate results in decreased expression of MFAP4 mRNA CTD PMID:21161181 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO diethyl maleate results in decreased activity of MGMT protein CTD PMID:16950796 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP diethyl maleate results in increased expression of MKI67 mRNA CTD PMID:21161181 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 decreases expression EXP diethyl maleate results in decreased expression of MKNK2 mRNA CTD PMID:21161181 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO diethyl maleate results in increased expression of MMP1 mRNA CTD PMID:33545341 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO diethyl maleate results in increased expression of MMP12 mRNA CTD PMID:10216232 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression EXP diethyl maleate results in decreased expression of MMP2 mRNA CTD PMID:21161181 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO diethyl maleate results in increased expression of MMP3 mRNA CTD PMID:33545341 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Msn moesin increases reduction ISO diethyl maleate results in increased reduction of MSN protein CTD PMID:19843705 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628
JBrowse link
G Mt1 metallothionein 1 increases expression ISO diethyl maleate results in increased expression of MT1A mRNA CTD PMID:20491607 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A increases expression ISO diethyl maleate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mx1 MX dynamin like GTPase 1 decreases expression EXP diethyl maleate results in decreased expression of MX1 mRNA; diethyl maleate results in decreased expression of MX2 mRNA CTD PMID:21161181 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression EXP diethyl maleate results in increased expression of MYBL2 mRNA CTD PMID:21161181 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression ISO diethyl maleate results in decreased expression of MYCN mRNA CTD PMID:25270620 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Nat8 N-acetyltransferase 8 decreases expression EXP diethyl maleate results in decreased expression of NAT8 mRNA CTD PMID:21161181 NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression EXP diethyl maleate results in increased expression of NCAPH mRNA CTD PMID:21161181 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO diethyl maleate results in increased expression of NDRG1 mRNA CTD PMID:33545341 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization
increases activity
increases expression
multiple interactions
decreases response to substance
ISO
EXP
diethyl maleate affects the localization of NFE2L2 protein
diethyl maleate results in increased activity of NFE2L2 protein
diethyl maleate results in increased expression of NFE2L2 protein
diethyl maleate binds to and results in increased activity of NFE2L2 protein; diethyl maleate results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
NFE2L2 results in decreased susceptibility to diethyl maleate
NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]
CTD PMID:12235164 PMID:20806931 PMID:21465251 PMID:22003191 PMID:27358234 More... NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA] CTD PMID:12774022 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO
Acetylcysteine inhibits the reaction [diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate] CTD PMID:7532384 PMID:9918918 PMID:12774022 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 increases expression ISO diethyl maleate results in increased expression of NOTCH1 mRNA CTD PMID:33545341 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO diethyl maleate results in increased expression of NQO1 mRNA CTD PMID:20491607 PMID:25270620 PMID:33545341 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression EXP diethyl maleate results in decreased expression of NR0B2 mRNA CTD PMID:21161181 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression EXP diethyl maleate results in decreased expression of NR1D1 mRNA CTD PMID:21161181 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP diethyl maleate results in decreased expression of NREP mRNA CTD PMID:21161181 NCBI chr18:25,017,069...25,046,564
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor decreases expression ISO diethyl maleate results in decreased expression of NSMF mRNA CTD PMID:25270620 NCBI chr 3:7,861,846...7,870,615
Ensembl chr 3:7,861,872...7,870,614
JBrowse link
G Ntf3 neurotrophin 3 decreases expression EXP diethyl maleate results in decreased expression of NTF3 mRNA CTD PMID:21161181 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Nup153 nucleoporin 153 multiple interactions
affects localization
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; diethyl maleate results in increased phosphorylation of and results in increased O-linked glycosylation of NUP153 protein CTD PMID:20041180 NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876
JBrowse link
G Nup88 nucleoporin 88 multiple interactions
affects localization
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] affects the reaction [diethyl maleate affects the localization of NUP88 protein]; diethyl maleate results in increased phosphorylation of and results in increased glycosylation of NUP88 protein CTD PMID:20041180 NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
JBrowse link
G Oaf out at first homolog decreases expression EXP diethyl maleate results in decreased expression of OAF mRNA CTD PMID:21161181 NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
JBrowse link
G Oas1i 2 ' -5 ' oligoadenylate synthetase 1I decreases expression EXP diethyl maleate results in decreased expression of OAS1I mRNA CTD PMID:21161181 NCBI chr12:35,624,566...35,636,608
Ensembl chr12:35,624,592...35,636,604
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions ISO [diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of OGG1 mRNA CTD PMID:22564015 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Orc1 origin recognition complex, subunit 1 increases expression EXP diethyl maleate results in increased expression of ORC1 mRNA CTD PMID:21161181 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 increases expression ISO diethyl maleate results in increased expression of OSGIN1 mRNA CTD PMID:33545341 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G P2rx7 purinergic receptor P2X 7 decreases expression EXP diethyl maleate results in decreased expression of P2RX7 mRNA CTD PMID:21161181 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO diethyl maleate results in increased cleavage of PARP1 protein CTD PMID:21105742 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 decreases expression EXP diethyl maleate results in decreased expression of PBLD protein CTD PMID:21161181 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO diethyl maleate results in decreased expression of PCNA mRNA CTD PMID:11875189 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdlim2 PDZ and LIM domain 2 decreases expression EXP diethyl maleate results in decreased expression of PDLIM2 mRNA CTD PMID:21161181 NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
JBrowse link
G Pdrg1 p53 and DNA damage regulated 1 increases expression ISO diethyl maleate results in increased expression of PDRG1 mRNA CTD PMID:25270620 NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858
Ensembl chr 3:141,476,501...141,483,858
JBrowse link
G Per2 period circadian regulator 2 decreases expression EXP diethyl maleate results in decreased expression of PER2 mRNA CTD PMID:21161181 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Per3 period circadian regulator 3 decreases expression EXP diethyl maleate results in decreased expression of PER3 mRNA CTD PMID:21161181 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
JBrowse link
G Pgd phosphogluconate dehydrogenase increases activity EXP diethyl maleate results in increased activity of PGD protein CTD PMID:3099627 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 increases expression ISO diethyl maleate results in increased expression of PGRMC1 mRNA CTD PMID:25270620 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682
JBrowse link
G Pir pirin increases expression ISO diethyl maleate results in increased expression of PIR mRNA CTD PMID:25270620 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Pklr pyruvate kinase L/R decreases expression EXP diethyl maleate results in decreased expression of PKLR mRNA CTD PMID:21161181 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Plat plasminogen activator, tissue type increases expression
decreases expression
EXP
ISO
diethyl maleate results in increased expression of PLAT mRNA
diethyl maleate results in decreased expression of PLAT mRNA
CTD PMID:21161181 PMID:25270620 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plek pleckstrin decreases expression EXP diethyl maleate results in decreased expression of PLEK mRNA CTD PMID:21161181 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 increases expression ISO diethyl maleate results in increased expression of PLEKHM1 mRNA CTD PMID:33545341 NCBI chr10:88,313,837...88,366,182
Ensembl chr10:88,314,651...88,362,412
JBrowse link
G Plin2 perilipin 2 increases expression ISO diethyl maleate results in increased expression of PLIN2 mRNA CTD PMID:33545341 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Plk1 polo-like kinase 1 increases expression ISO diethyl maleate results in increased expression of PLK1 mRNA CTD PMID:33545341 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO diethyl maleate results in increased expression of PLK3 mRNA CTD PMID:33545341 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO diethyl maleate results in increased expression of POU5F1 mRNA CTD PMID:33545341 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases activity
EXP diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol inhibits the reaction [diethyl maleate results in decreased activity of PPARA protein]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate results in decreased activity of PPARA protein] CTD PMID:17134953 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1b PPARG coactivator 1 beta decreases expression EXP diethyl maleate results in decreased expression of PPARGC1B mRNA CTD PMID:21161181 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression EXP diethyl maleate results in decreased expression of PPP1R3B mRNA CTD PMID:21161181 NCBI chr16:56,830,011...56,842,395
Ensembl chr16:56,829,660...56,842,406
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression EXP diethyl maleate results in decreased expression of PPP1R3C mRNA CTD PMID:21161181 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
JBrowse link
G Prdm14 PR/SET domain 14 decreases expression ISO diethyl maleate results in decreased expression of PRDM14 mRNA CTD PMID:25270620 NCBI chr 5:6,082,163...6,092,712
Ensembl chr 5:6,082,442...6,092,712
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression EXP
ISO
diethyl maleate results in increased expression of PRDX1 mRNA CTD PMID:9506838 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 decreases expression ISO diethyl maleate results in decreased expression of PRKAB1 mRNA CTD PMID:25270620 NCBI chr12:40,588,140...40,598,673
Ensembl chr12:40,588,211...40,598,661
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 increases expression ISO diethyl maleate results in increased expression of PRKAG2 mRNA CTD PMID:33545341 NCBI chr 4:10,010,574...10,252,152
Ensembl chr 4:10,010,890...10,252,142
JBrowse link
G Prkcb protein kinase C, beta affects expression ISO diethyl maleate affects the expression of PRKCB protein CTD PMID:31958493 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcd protein kinase C, delta multiple interactions EXP Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCD protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCD protein CTD PMID:11118818 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCE protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCE protein CTD PMID:11118818 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prss8 serine protease 8 decreases expression EXP diethyl maleate results in decreased expression of PRSS8 mRNA CTD PMID:21161181 NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO diethyl maleate results in increased expression of PTGR1 mRNA CTD PMID:25270620 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptpn14 protein tyrosine phosphatase, non-receptor type 14 increases expression ISO diethyl maleate results in increased expression of PTPN14 mRNA CTD PMID:25270620 NCBI chr13:101,268,258...101,420,508
Ensembl chr13:101,268,416...101,414,088
JBrowse link
G Pus1 pseudouridine synthase 1 decreases expression ISO diethyl maleate results in decreased expression of PUS1 mRNA CTD PMID:25270620 NCBI chr12:45,880,364...45,889,196
Ensembl chr12:45,880,440...45,889,196
JBrowse link
G Pxn paxillin increases expression ISO diethyl maleate results in increased expression of PXN mRNA CTD PMID:33545341 NCBI chr12:41,060,791...41,107,962
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Rab27a RAB27A, member RAS oncogene family decreases expression EXP diethyl maleate results in decreased expression of RAB27A mRNA CTD PMID:21161181 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] CTD PMID:20116392 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rho rhodopsin increases expression ISO diethyl maleate results in increased expression of RHO mRNA CTD PMID:33545341 NCBI chr 4:148,975,597...148,988,693
Ensembl chr 4:148,980,611...148,985,773
JBrowse link
G Rnf114 ring finger protein 114 decreases expression ISO diethyl maleate results in decreased expression of RNF114 mRNA CTD PMID:25270620 NCBI chr 3:156,222,487...156,234,263
Ensembl chr 3:156,222,498...156,234,256
JBrowse link
G Rnf14 ring finger protein 14 increases expression ISO diethyl maleate results in increased expression of RNF14 mRNA CTD PMID:25270620 NCBI chr18:30,131,627...30,155,686
Ensembl chr18:30,131,691...30,155,685
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression EXP
ISO
diethyl maleate results in increased expression of RRM2 mRNA CTD PMID:21161181 PMID:33545341 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression EXP diethyl maleate results in decreased expression of RSAD2 mRNA CTD PMID:21161181 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 decreases expression EXP diethyl maleate results in decreased expression of RT1-S3 mRNA CTD PMID:21161181 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression EXP diethyl maleate results in decreased expression of S100A9 mRNA CTD PMID:21161181 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Sash3 SAM and SH3 domain containing 3 decreases expression EXP diethyl maleate results in decreased expression of SASH3 mRNA CTD PMID:21161181 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP diethyl maleate results in decreased expression of SCD1 mRNA CTD PMID:21161181 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sds serine dehydratase decreases expression EXP diethyl maleate results in decreased expression of SDS mRNA CTD PMID:21161181 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Serpind1 serpin family D member 1 decreases expression ISO diethyl maleate results in decreased expression of SERPIND1 mRNA CTD PMID:25270620 NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519
JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO diethyl maleate results in increased expression of SERTAD1 mRNA CTD PMID:33545341 NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091
JBrowse link
G Sez6 seizure related 6 homolog decreases expression EXP diethyl maleate results in decreased expression of SEZ6 mRNA CTD PMID:21161181 NCBI chr10:62,818,931...62,868,686
Ensembl chr10:62,819,069...62,868,671
JBrowse link
G Sfxn1 sideroflexin 1 decreases expression ISO diethyl maleate results in decreased expression of SFXN1 mRNA CTD PMID:25270620 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 increases expression ISO diethyl maleate results in increased expression of SH3BP5 mRNA CTD PMID:33545341 NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975
JBrowse link
G Six4 SIX homeobox 4 increases expression ISO diethyl maleate results in increased expression of SIX4 mRNA CTD PMID:25270620 NCBI chr 6:91,802,328...91,816,062
Ensembl chr 6:91,802,329...91,815,992
JBrowse link
G Slc16a6 solute carrier family 16, member 6 decreases expression ISO diethyl maleate results in decreased expression of SLC16A6 mRNA CTD PMID:25270620 NCBI chr10:94,424,377...94,447,984
Ensembl chr10:94,426,244...94,448,779
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO diethyl maleate results in increased expression of SLC1A4 mRNA CTD PMID:25270620 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP diethyl maleate results in decreased expression of SLC2A2 mRNA CTD PMID:21161181 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression EXP diethyl maleate results in decreased expression of SLC2A5 mRNA CTD PMID:21161181 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc39a14 solute carrier family 39 member 14 decreases expression ISO diethyl maleate results in decreased expression of SLC39A14 mRNA CTD PMID:25270620 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO diethyl maleate results in increased expression of SLC3A2 mRNA CTD PMID:33545341 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO diethyl maleate inhibits the reaction [Lipopolysaccharides results in decreased expression of SLC40A1 mRNA] CTD PMID:21303654 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc44a4 solute carrier family 44, member 4 decreases expression EXP diethyl maleate results in decreased expression of SLC44A4 mRNA CTD PMID:21161181 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions
increases expression
ISO NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA] CTD PMID:12235164 PMID:33545341 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 decreases expression EXP diethyl maleate results in decreased expression of SLC9A3R1 mRNA CTD PMID:21161181 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 decreases expression EXP diethyl maleate results in decreased expression of SLCO2A1 mRNA CTD PMID:21161181 NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546
JBrowse link
G Slfn3 schlafen family member 3 decreases expression EXP diethyl maleate results in decreased expression of SLFN3 mRNA CTD PMID:21161181 NCBI chr10:68,020,482...68,060,248 JBrowse link
G Smc4 structural maintenance of chromosomes 4 increases expression EXP diethyl maleate results in increased expression of SMC4 mRNA CTD PMID:21161181 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
JBrowse link
G Smtn smoothelin increases expression EXP diethyl maleate results in increased expression of SMTN mRNA CTD PMID:21161181 NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression ISO diethyl maleate results in decreased expression of SOCS3 mRNA CTD PMID:25270620 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sorl1 sortilin related receptor 1 decreases expression EXP diethyl maleate results in decreased expression of SORL1 mRNA CTD PMID:21161181 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Sox9 SRY-box transcription factor 9 increases expression EXP diethyl maleate results in increased expression of SOX9 mRNA CTD PMID:21161181 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sp5 Sp5 transcription factor decreases expression ISO diethyl maleate results in decreased expression of SP5 mRNA CTD PMID:25270620 NCBI chr 3:55,274,931...55,277,733
Ensembl chr 3:55,274,931...55,277,733
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex increases expression EXP diethyl maleate results in increased expression of SPC25 mRNA CTD PMID:21161181 NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
JBrowse link
G Spta1 spectrin, alpha, erythrocytic 1 increases expression ISO diethyl maleate results in increased expression of SPTA1 mRNA CTD PMID:25270620 NCBI chr13:86,203,504...86,279,371
Ensembl chr13:86,203,504...86,279,371
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases cleavage ISO diethyl maleate results in increased cleavage of SPTAN1 protein CTD PMID:21105742 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 increases expression ISO diethyl maleate results in increased expression of SPTBN4 mRNA CTD PMID:25270620 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 increases expression ISO diethyl maleate results in increased expression of SPTLC1 mRNA CTD PMID:33545341 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO diethyl maleate results in increased expression of SQSTM1 mRNA CTD PMID:25270620 PMID:33545341 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP diethyl maleate results in decreased expression of SREBF1 mRNA CTD PMID:21161181 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions
decreases expression
increases expression
ISO [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]
diethyl maleate results in decreased expression of SRXN1 mRNA
NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
diethyl maleate results in increased expression of SRXN1 mRNA; diethyl maleate results in increased expression of SRXN1 protein
CTD PMID:22003191 PMID:25270620 PMID:27358234 PMID:27982581 PMID:33545341 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression EXP diethyl maleate results in decreased expression of STAT1 mRNA CTD PMID:21161181 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Steap4 STEAP4 metalloreductase decreases expression ISO diethyl maleate results in decreased expression of STEAP4 mRNA CTD PMID:25270620 NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859
JBrowse link
G Sulf2 sulfatase 2 decreases expression EXP diethyl maleate results in decreased expression of SULF2 mRNA CTD PMID:21161181 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP diethyl maleate results in decreased expression of SULT1A1 protein CTD PMID:21161181 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Tagln transgelin decreases expression EXP diethyl maleate results in decreased expression of TAGLN mRNA CTD PMID:21161181 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tatdn2 TatD DNase domain containing 2 increases expression ISO diethyl maleate results in increased expression of TATDN2 mRNA CTD PMID:33545341 NCBI chr 4:146,845,156...146,865,708
Ensembl chr 4:146,845,156...146,860,897
JBrowse link
G Tbcel tubulin folding cofactor E-like increases expression ISO diethyl maleate results in increased expression of TBCEL mRNA CTD PMID:25270620 NCBI chr 8:42,795,648...42,854,552
Ensembl chr 8:42,796,730...42,854,552
JBrowse link
G Tent4a terminal nucleotidyltransferase 4A increases expression ISO diethyl maleate results in increased expression of TENT4A mRNA CTD PMID:33545341 NCBI chr 1:33,766,121...33,799,433
Ensembl chr 1:33,765,672...33,799,433
JBrowse link
G Tent5a terminal nucleotidyltransferase 5A decreases expression EXP diethyl maleate results in decreased expression of TENT5A mRNA CTD PMID:21161181 NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045
JBrowse link
G Tesmin testis expressed metallothionein like protein affects localization ISO diethyl maleate affects the localization of TESMIN protein CTD PMID:12606435 NCBI chr 1:200,629,688...200,648,434
Ensembl chr 1:200,630,144...200,648,433
JBrowse link
G Tf transferrin decreases expression EXP diethyl maleate results in decreased expression of TF protein CTD PMID:21161181 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfeb transcription factor EB decreases expression ISO diethyl maleate results in decreased expression of TFEB mRNA CTD PMID:25270620 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
JBrowse link
G Tgm2 transglutaminase 2 increases expression EXP diethyl maleate results in increased expression of TGM2 mRNA CTD PMID:21161181 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP diethyl maleate results in increased expression of THBS1 mRNA CTD PMID:21161181 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP diethyl maleate results in decreased expression of THRSP mRNA CTD PMID:21161181 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 increases expression EXP diethyl maleate results in increased expression of TM4SF1 mRNA CTD PMID:21161181 NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
JBrowse link
G Tmem209 transmembrane protein 209 increases expression ISO diethyl maleate results in increased expression of TMEM209 mRNA CTD PMID:25270620 NCBI chr 4:59,101,656...59,128,687
Ensembl chr 4:59,101,550...59,128,630
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein]
diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate]
diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]
CTD PMID:7476933 PMID:7532384 PMID:12774022 PMID:20116392 PMID:31958493 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 decreases expression EXP diethyl maleate results in decreased expression of TNFRSF14 mRNA CTD PMID:21161181 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]
TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
CTD PMID:22003191 PMID:27982581 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpm2 tropomyosin 2 decreases expression EXP diethyl maleate results in decreased expression of TPM2 mRNA CTD PMID:21161181 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992
JBrowse link
G Trap1 TNF receptor-associated protein 1 multiple interactions
decreases response to substance
ISO diethyl maleate inhibits the reaction [Cisplatin results in decreased expression of TRAP1 protein]
TRAP1 protein results in decreased susceptibility to diethyl maleate
CTD PMID:17853063 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 decreases expression ISO diethyl maleate results in decreased expression of TRDMT1 mRNA CTD PMID:25270620 NCBI chr17:76,601,966...76,646,104
Ensembl chr17:76,610,543...76,645,439
JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO diethyl maleate results in increased expression of TRIB1 mRNA CTD PMID:33545341 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO diethyl maleate results in increased expression of TRIB3 mRNA CTD PMID:33545341 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trim6 tripartite motif containing 6 decreases expression EXP diethyl maleate results in decreased expression of TRIM6 mRNA CTD PMID:21161181 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 increases expression EXP diethyl maleate results in increased expression of TRIP13 mRNA CTD PMID:21161181 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP diethyl maleate results in decreased expression of TSC22D1 mRNA CTD PMID:21161181 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
G Tspan8 tetraspanin 8 decreases expression EXP diethyl maleate results in decreased expression of TSPAN8 mRNA CTD PMID:21161181 NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356
JBrowse link
G Tstd1 thiosulfate sulfurtransferase like domain containing 1 decreases expression ISO diethyl maleate results in decreased expression of TSTD1 mRNA CTD PMID:25270620 NCBI chr13:83,853,421...83,854,875 JBrowse link
G Txn1 thioredoxin 1 decreases activity ISO diethyl maleate results in decreased activity of TXN protein CTD PMID:15388247 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txnip thioredoxin interacting protein increases expression EXP diethyl maleate results in increased expression of TXNIP mRNA CTD PMID:21161181 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO diethyl maleate results in increased expression of TXNRD1 mRNA CTD PMID:15521073 PMID:33545341 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ubd ubiquitin D decreases expression EXP diethyl maleate results in decreased expression of UBD mRNA CTD PMID:21161181 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 increases expression EXP diethyl maleate results in increased expression of UHRF1 mRNA CTD PMID:21161181 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
JBrowse link
G Usp18 ubiquitin specific peptidase 18 decreases expression EXP diethyl maleate results in decreased expression of USP18 mRNA CTD PMID:21161181 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression EXP diethyl maleate results in decreased expression of USP2 mRNA CTD PMID:21161181 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO diethyl maleate results in increased expression of VEGFA mRNA CTD PMID:33545341 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wdr31 WD repeat domain 31 decreases expression ISO diethyl maleate results in decreased expression of WDR31 mRNA CTD PMID:25270620 NCBI chr 5:75,897,074...75,917,461
Ensembl chr 5:75,898,353...75,917,417
JBrowse link
G Wdr6 WD repeat domain 6 decreases expression EXP diethyl maleate results in decreased expression of WDR6 mRNA CTD PMID:21161181 NCBI chr 8:109,268,079...109,274,504
Ensembl chr 8:109,268,079...109,274,499
JBrowse link
G Ypel5 yippee-like 5 increases expression ISO diethyl maleate results in increased expression of YPEL5 mRNA CTD PMID:25270620 NCBI chr 6:22,656,284...22,671,741
Ensembl chr 6:22,656,285...22,671,691
JBrowse link
G Zfand2a zinc finger AN1-type containing 2A increases expression ISO diethyl maleate results in increased expression of ZFAND2A mRNA CTD PMID:33545341 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
JBrowse link
G Zfp36 zinc finger protein 36 increases expression ISO diethyl maleate results in increased expression of ZFP36 protein CTD PMID:21969073 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp367 zinc finger protein 367 increases expression EXP diethyl maleate results in increased expression of ZNF367 mRNA CTD PMID:21161181 NCBI chr17:965,161...984,290
Ensembl chr17:965,161...984,287
JBrowse link
G Znrd2 zinc ribbon domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of ZNRD2 mRNA CTD PMID:25270620 NCBI chr 1:203,017,682...203,019,465
Ensembl chr 1:203,017,682...203,019,465
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        glutathione depleting agent 384
          diethyl maleate 384
paths to the root