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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glutathione depleting agent
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Accession:CHEBI:68509 term browser browse the term
Definition:A compound which causes a reduction in the levels of glutathione in cells.
Synonyms:related_synonym: glutathione depleting agents;   glutathione depletion agent;   glutathione depletion agents;   glutathione depletor;   glutathione depletors



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diethyl maleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 increases expression ISO diethyl maleate results in increased expression of ABCC2 mRNA CTD PMID:25270620 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO diethyl maleate results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr14:22,598,300...22,612,963
Ensembl chr14:22,598,290...22,612,963
JBrowse link
G ACACA acetyl-CoA carboxylase alpha decreases expression ISO diethyl maleate results in decreased expression of ACACA mRNA CTD PMID:25270620 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
JBrowse link
G ACOX1 acyl-CoA oxidase 1 multiple interactions ISO diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]] CTD PMID:17134953 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
JBrowse link
G ACY3 aminoacylase 3 decreases expression ISO diethyl maleate results in decreased expression of ACY3 mRNA CTD PMID:21161181 NCBI chr11:67,642,555...67,650,730
Ensembl chr11:67,642,555...67,650,730
JBrowse link
G ADM adrenomedullin increases expression EXP diethyl maleate results in increased expression of ADM mRNA CTD PMID:33545341 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
JBrowse link
G ADORA3 adenosine A3 receptor decreases expression ISO diethyl maleate results in decreased expression of ADORA3 mRNA CTD PMID:21161181 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
JBrowse link
G AEN apoptosis enhancing nuclease increases expression EXP diethyl maleate results in increased expression of AEN mRNA CTD PMID:33545341 NCBI chr15:88,604,683...88,632,281
Ensembl chr15:88,621,337...88,632,281
JBrowse link
G AFP alpha fetoprotein increases expression ISO diethyl maleate results in increased expression of AFP mRNA CTD PMID:25270620 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 increases expression ISO diethyl maleate results in increased expression of AHCYL1 mRNA CTD PMID:25270620 NCBI chr 1:109,984,765...110,023,742
Ensembl chr 1:109,984,765...110,023,742
JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 increases expression ISO diethyl maleate results in increased expression of AKR1A1 protein CTD PMID:21161181 NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049
JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 increases expression EXP diethyl maleate results in increased expression of AKR1B10 mRNA CTD PMID:33545341 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
JBrowse link
G AKR1C2 aldo-keto reductase family 1 member C2 increases expression EXP diethyl maleate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 affects reduction ISO diethyl maleate affects the reduction of ALDH1A1 protein CTD PMID:19843705 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ALDH1B1 aldehyde dehydrogenase 1 family member B1 decreases expression ISO diethyl maleate results in decreased expression of ALDH1B1 mRNA CTD PMID:21161181 NCBI chr 9:38,392,702...38,398,661
Ensembl chr 9:38,392,702...38,398,661
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member decreases reduction
increases expression
decreases expression
ISO diethyl maleate results in decreased reduction of ALDH2 protein
diethyl maleate results in increased expression of ALDH2 protein
diethyl maleate results in decreased expression of ALDH2 protein
CTD PMID:19843705 PMID:21161181 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALDOA aldolase, fructose-bisphosphate A affects expression EXP diethyl maleate affects the expression of ALDOA mRNA CTD PMID:34480604 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
JBrowse link
G ALDOB aldolase, fructose-bisphosphate B decreases expression ISO diethyl maleate results in decreased expression of ALDOB protein CTD PMID:21161181 NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664
JBrowse link
G AMIGO2 adhesion molecule with Ig like domain 2 decreases expression ISO diethyl maleate results in decreased expression of AMIGO2 mRNA CTD PMID:21161181 NCBI chr12:47,075,707...47,079,959
Ensembl chr12:47,075,707...47,079,959
JBrowse link
G ANGPTL2 angiopoietin like 2 decreases expression ISO diethyl maleate results in decreased expression of ANGPTL2 mRNA CTD PMID:21161181 NCBI chr 9:127,087,348...127,122,635
Ensembl chr 9:127,087,348...127,122,635
JBrowse link
G ANGPTL4 angiopoietin like 4 increases expression EXP diethyl maleate results in increased expression of ANGPTL4 mRNA CTD PMID:33545341 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
JBrowse link
G ANKRD46 ankyrin repeat domain 46 decreases expression ISO diethyl maleate results in decreased expression of ANKRD46 mRNA CTD PMID:21161181 NCBI chr 8:100,509,752...100,559,759
Ensembl chr 8:100,509,752...100,559,784
JBrowse link
G ANLN anillin, actin binding protein increases expression ISO diethyl maleate results in increased expression of ANLN mRNA CTD PMID:21161181 NCBI chr 7:36,389,862...36,453,791
Ensembl chr 7:36,389,821...36,453,791
JBrowse link
G ANXA1 annexin A1 affects expression EXP diethyl maleate affects the expression of ANXA1 mRNA CTD PMID:34480604 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G ANXA3 annexin A3 decreases expression ISO diethyl maleate results in decreased expression of ANXA3 mRNA CTD PMID:21161181 NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451
JBrowse link
G AP3M2 adaptor related protein complex 3 subunit mu 2 decreases expression ISO diethyl maleate results in decreased expression of AP3M2 mRNA CTD PMID:21161181 NCBI chr 8:42,153,063...42,171,183
Ensembl chr 8:42,152,946...42,171,673
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression EXP diethyl maleate results in increased expression of APAF1 mRNA CTD PMID:11875189 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433
JBrowse link
G APLP1 amyloid beta precursor like protein 1 decreases expression ISO diethyl maleate results in decreased expression of APLP1 mRNA CTD PMID:25270620 NCBI chr19:35,868,574...35,879,792
Ensembl chr19:35,867,899...35,879,792
JBrowse link
G APOL4 apolipoprotein L4 decreases expression ISO diethyl maleate results in decreased expression of APOL9A mRNA CTD PMID:21161181 NCBI chr22:36,189,128...36,204,833
Ensembl chr22:36,189,124...36,204,840
JBrowse link
G ARHGAP9 Rho GTPase activating protein 9 increases expression EXP diethyl maleate results in increased expression of ARHGAP9 mRNA CTD PMID:33545341 NCBI chr12:57,472,269...57,488,824
Ensembl chr12:57,472,264...57,488,814
JBrowse link
G ARRDC2 arrestin domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of ARRDC2 mRNA CTD PMID:21161181 NCBI chr19:18,001,124...18,014,102
Ensembl chr19:18,001,132...18,014,102
JBrowse link
G ARRDC4 arrestin domain containing 4 decreases expression ISO diethyl maleate results in decreased expression of ARRDC4 mRNA CTD PMID:25270620 NCBI chr15:97,960,703...97,973,833
Ensembl chr15:97,960,703...97,973,833
JBrowse link
G ASF1B anti-silencing function 1B histone chaperone increases expression ISO diethyl maleate results in increased expression of ASF1B mRNA CTD PMID:21161181 NCBI chr19:14,119,512...14,136,589
Ensembl chr19:14,119,512...14,136,613
JBrowse link
G ASXL1 ASXL transcriptional regulator 1 decreases expression ISO diethyl maleate results in decreased expression of ASXL1 mRNA CTD PMID:25270620 NCBI chr20:32,358,331...32,439,319
Ensembl chr20:32,358,330...32,439,319
JBrowse link
G ATM ATM serine/threonine kinase increases expression EXP diethyl maleate results in increased expression of ATM mRNA CTD PMID:11875189 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,823...108,369,102
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta increases expression ISO diethyl maleate results in increased expression of ATP5F1B protein CTD PMID:21161181 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G AURKA aurora kinase A increases expression
decreases expression
ISO diethyl maleate results in increased expression of AURKA mRNA
diethyl maleate results in decreased expression of AURKA mRNA
CTD PMID:21161181 PMID:25270620 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337
JBrowse link
G BABAM2-AS1 BABAM2 antisense RNA 1 increases expression EXP diethyl maleate results in increased expression of BABAM2-AS1 mRNA CTD PMID:33545341 NCBI chr 2:27,889,456...27,891,114 JBrowse link
G BBC3 BCL2 binding component 3 increases expression EXP diethyl maleate results in increased expression of BBC3 mRNA CTD PMID:33545341 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
increases expression
ISO
EXP
[diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of BCL2 mRNA
diethyl maleate results in increased expression of BCL2 mRNA
CTD PMID:22564015 PMID:33545341 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2A1 BCL2 related protein A1 decreases expression ISO diethyl maleate results in decreased expression of BCL2A1 mRNA CTD PMID:21161181 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
JBrowse link
G BCL3 BCL3 transcription coactivator decreases expression ISO diethyl maleate results in decreased expression of BCL3 mRNA CTD PMID:25270620 NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044
JBrowse link
G BCL6B BCL6B transcription repressor decreases expression ISO diethyl maleate results in decreased expression of BCL6B mRNA CTD PMID:21161181 NCBI chr17:7,023,050...7,029,644
Ensembl chr17:7,023,050...7,030,290
JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 decreases expression ISO diethyl maleate results in decreased expression of BHLHE41 mRNA CTD PMID:21161181 NCBI chr12:26,120,030...26,125,037
Ensembl chr12:26,120,030...26,125,037
JBrowse link
G BHMT betaine--homocysteine S-methyltransferase decreases expression ISO diethyl maleate results in decreased expression of BHMT mRNA CTD PMID:21161181 NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 multiple interactions ISO diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA] CTD PMID:12774022 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
JBrowse link
G BLVRB biliverdin reductase B increases expression ISO diethyl maleate results in increased expression of BLVRB mRNA CTD PMID:25270620 PMID:34626751 NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764
JBrowse link
G BMF Bcl2 modifying factor decreases expression ISO diethyl maleate results in decreased expression of BMF mRNA CTD PMID:21161181 NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
JBrowse link
G BRIP1 BRCA1 interacting helicase 1 increases expression ISO diethyl maleate results in increased expression of BRIP1 mRNA CTD PMID:21161181 NCBI chr17:61,679,139...61,863,528
Ensembl chr17:61,679,139...61,863,559
JBrowse link
G BTBD2 BTB domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of BTBD2 mRNA CTD PMID:21161181 NCBI chr19:1,985,448...2,015,714
Ensembl chr19:1,985,438...2,034,881
JBrowse link
G BTG2 BTG anti-proliferation factor 2 increases expression
decreases expression
multiple interactions
ISO diethyl maleate results in increased expression of BTG2 mRNA
diethyl maleate results in decreased expression of BTG2 mRNA
NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]
CTD PMID:22003191 PMID:25270620 PMID:34626751 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
JBrowse link
G C6 complement C6 decreases expression ISO diethyl maleate results in decreased expression of C6 mRNA CTD PMID:21161181 NCBI chr 5:41,142,116...41,261,469
Ensembl chr 5:41,142,116...41,261,438
JBrowse link
G CASP2 caspase 2 increases expression EXP diethyl maleate results in increased expression of CASP2 mRNA CTD PMID:11875189 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696
JBrowse link
G CASP3 caspase 3 increases expression
increases cleavage
EXP diethyl maleate results in increased expression of CASP3 mRNA
diethyl maleate results in increased cleavage of CASP3 protein
CTD PMID:11875189 PMID:21105742 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP9 caspase 9 increases expression EXP diethyl maleate results in increased expression of CASP9 mRNA CTD PMID:11875189 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases expression ISO diethyl maleate results in decreased expression of CAT protein CTD PMID:21161181 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CBR1 carbonyl reductase 1 increases expression ISO diethyl maleate results in increased expression of CBR1 mRNA CTD PMID:25270620 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
JBrowse link
G CBR3 carbonyl reductase 3 increases expression
multiple interactions
EXP
ISO
diethyl maleate results in increased expression of CBR3 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diethyl maleate results in increased expression of CBR3 mRNA]
CTD PMID:20806931 PMID:25270620 NCBI chr21:36,135,079...36,146,562
Ensembl chr21:36,135,079...36,146,562
JBrowse link
G CBX4 chromobox 4 increases expression EXP diethyl maleate results in increased expression of CBX4 mRNA CTD PMID:33545341 NCBI chr17:79,833,156...79,839,440
Ensembl chr17:79,833,156...79,839,440
JBrowse link
G CCDC50 coiled-coil domain containing 50 decreases expression ISO diethyl maleate results in decreased expression of CCDC50 mRNA CTD PMID:25270620 NCBI chr 3:191,329,394...191,398,659
Ensembl chr 3:191,329,085...191,398,659
JBrowse link
G CCNA1 cyclin A1 decreases expression EXP diethyl maleate results in decreased expression of CCNA1 mRNA CTD PMID:11875189 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870
JBrowse link
G CCNA2 cyclin A2 increases expression ISO diethyl maleate results in increased expression of CCNA2 mRNA CTD PMID:21161181 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
JBrowse link
G CCND1 cyclin D1 decreases expression
increases expression
EXP
ISO
diethyl maleate results in decreased expression of CCND1 mRNA
diethyl maleate results in increased expression of CCND1 mRNA
CTD PMID:11875189 PMID:21161181 PMID:25270620 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCNE2 cyclin E2 increases expression ISO diethyl maleate results in increased expression of CCNE2 mRNA CTD PMID:21161181 NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678
JBrowse link
G CCNK cyclin K decreases expression EXP diethyl maleate results in decreased expression of CCNK mRNA CTD PMID:11875189 NCBI chr14:99,481,409...99,512,440
Ensembl chr14:99,481,169...99,535,044
JBrowse link
G CD80 CD80 molecule multiple interactions
increases expression
EXP [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein
diethyl maleate results in increased expression of CD80 protein
CTD PMID:31958493 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614
JBrowse link
G CD86 CD86 molecule multiple interactions
increases expression
EXP [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; bisindolylmaleimide I inhibits the reaction [diethyl maleate results in increased expression of CD86 protein] CTD PMID:24136171 PMID:31958493 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDC25A cell division cycle 25A increases expression ISO diethyl maleate results in increased expression of CDC25A mRNA CTD PMID:21161181 NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417
JBrowse link
G CDCA2 cell division cycle associated 2 increases expression ISO diethyl maleate results in increased expression of CDCA2 mRNA CTD PMID:21161181 NCBI chr 8:25,458,931...25,507,917
Ensembl chr 8:25,459,199...25,507,911
JBrowse link
G CDCA3 cell division cycle associated 3 increases expression ISO diethyl maleate results in increased expression of CDCA3 mRNA CTD PMID:21161181 NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292
JBrowse link
G CDCA8 cell division cycle associated 8 increases expression ISO diethyl maleate results in increased expression of CDCA8 mRNA CTD PMID:21161181 NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719
JBrowse link
G CDH11 cadherin 11 decreases expression ISO diethyl maleate results in decreased expression of CDH11 mRNA CTD PMID:21161181 NCBI chr16:64,943,753...65,123,744
Ensembl chr16:64,943,753...65,126,112
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression
multiple interactions
EXP diethyl maleate results in increased expression of CDKN1A mRNA; diethyl maleate results in increased expression of CDKN1A protein
TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]
CTD PMID:11875189 PMID:27982581 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDS2 CDP-diacylglycerol synthase 2 increases expression ISO diethyl maleate results in increased expression of CDS2 mRNA CTD PMID:25270620 NCBI chr20:5,127,008...5,197,887
Ensembl chr20:5,126,879...5,197,887
JBrowse link
G CES1 carboxylesterase 1 increases reduction
decreases expression
ISO diethyl maleate results in increased reduction of CES1D protein
diethyl maleate results in decreased expression of CES1D protein
CTD PMID:19843705 PMID:21161181 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator decreases expression ISO diethyl maleate results in decreased expression of CFLAR mRNA CTD PMID:21161181 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit increases expression EXP diethyl maleate results in increased expression of CHRNA4 mRNA CTD PMID:33545341 NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401
JBrowse link
G CIDEC cell death inducing DFFA like effector c decreases expression ISO diethyl maleate results in decreased expression of CIDEC mRNA CTD PMID:21161181 NCBI chr 3:9,866,710...9,880,253
Ensembl chr 3:9,866,711...9,880,255
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 decreases expression ISO diethyl maleate results in decreased expression of CITED2 mRNA CTD PMID:21161181 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
JBrowse link
G CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 decreases expression ISO diethyl maleate results in decreased expression of CITED4 mRNA CTD PMID:21161181 NCBI chr 1:40,861,054...40,862,363
Ensembl chr 1:40,861,054...40,862,363
JBrowse link
G CKB creatine kinase B decreases reduction ISO diethyl maleate results in decreased reduction of CKB protein CTD PMID:19843705 NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
JBrowse link
G CKS2 CDC28 protein kinase regulatory subunit 2 increases expression EXP diethyl maleate results in increased expression of CKS2 mRNA CTD PMID:33545341 NCBI chr 9:89,311,195...89,316,703
Ensembl chr 9:89,311,195...89,316,703
JBrowse link
G CLK1 CDC like kinase 1 increases expression EXP diethyl maleate results in increased expression of CLK1 mRNA CTD PMID:33545341 NCBI chr 2:200,853,009...200,864,658
Ensembl chr 2:200,853,009...200,864,691
JBrowse link
G CMPK2 cytidine/uridine monophosphate kinase 2 decreases expression ISO diethyl maleate results in decreased expression of CMPK2 mRNA CTD PMID:21161181 NCBI chr 2:6,840,553...6,866,635
Ensembl chr 2:6,840,570...6,866,635
JBrowse link
G CNTN1 contactin 1 increases expression EXP diethyl maleate results in increased expression of CNTN1 mRNA CTD PMID:33545341 NCBI chr12:40,692,439...41,072,415
Ensembl chr12:40,692,439...41,072,415
JBrowse link
G COL1A1 collagen type I alpha 1 chain decreases expression ISO diethyl maleate results in decreased expression of COL1A1 mRNA CTD PMID:21161181 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL3A1 collagen type III alpha 1 chain decreases expression ISO diethyl maleate results in decreased expression of COL3A1 mRNA CTD PMID:25270620 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G COMMD3 COMM domain containing 3 increases expression ISO diethyl maleate results in increased expression of COMMD3 mRNA CTD PMID:25270620 NCBI chr10:22,316,388...22,320,306
Ensembl chr10:22,316,386...22,320,306
JBrowse link
G COMT catechol-O-methyltransferase decreases expression ISO diethyl maleate results in decreased expression of COMT mRNA CTD PMID:21161181 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
JBrowse link
G CP ceruloplasmin decreases expression ISO diethyl maleate results in decreased expression of CP mRNA CTD PMID:25270620 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CPSF4L cleavage and polyadenylation specific factor 4 like increases expression EXP diethyl maleate results in increased expression of CPSF4L mRNA CTD PMID:33545341 NCBI chr17:73,242,101...73,263,778
Ensembl chr17:73,248,449...73,262,352
JBrowse link
G CRYM crystallin mu decreases expression ISO diethyl maleate results in decreased expression of CRYM mRNA CTD PMID:21161181 NCBI chr16:21,258,521...21,303,062
Ensembl chr16:21,238,874...21,303,083
JBrowse link
G CSRP1 cysteine and glycine rich protein 1 decreases expression ISO diethyl maleate results in decreased expression of CSRP1 mRNA CTD PMID:21161181 NCBI chr 1:201,483,530...201,507,123
Ensembl chr 1:201,483,530...201,509,456
JBrowse link
G CSRP3 cysteine and glycine rich protein 3 decreases reduction ISO diethyl maleate results in decreased reduction of CSRP3 protein CTD PMID:19843705 NCBI chr11:19,182,030...19,201,983
Ensembl chr11:19,182,030...19,210,571
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 decreases expression ISO diethyl maleate results in decreased expression of CXCL10 mRNA CTD PMID:21161181 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 decreases expression ISO diethyl maleate results in decreased expression of CXCL12 mRNA CTD PMID:21161181 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions
increases secretion
increases stability
EXP diethyl maleate results in increased expression of CXCL8 mRNA; diethyl maleate results in increased expression of CXCL8 protein
bisindolylmaleimide I inhibits the reaction [diethyl maleate results in increased expression of CXCL8 protein]
diethyl maleate results in increased secretion of CXCL8 protein
diethyl maleate results in increased stability of CXCL8 mRNA
CTD PMID:20491607 PMID:20541004 PMID:21920952 PMID:21969073 PMID:24136171 More... NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 decreases expression ISO diethyl maleate results in decreased expression of CXCL9 mRNA CTD PMID:21161181 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G CYB5A cytochrome b5 type A increases expression ISO diethyl maleate results in increased expression of CYB5A mRNA CTD PMID:25270620 NCBI chr18:74,250,846...74,291,963
Ensembl chr18:74,250,846...74,291,973
JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 decreases expression ISO diethyl maleate results in decreased expression of CYP26B1 mRNA CTD PMID:21161181 NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862
JBrowse link
G DBP D-box binding PAR bZIP transcription factor decreases expression ISO diethyl maleate results in decreased expression of DBP mRNA CTD PMID:21161181 NCBI chr19:48,630,030...48,637,379
Ensembl chr19:48,630,030...48,637,379
JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP diethyl maleate results in increased expression of DDIT3 mRNA; diethyl maleate results in increased expression of DDIT3 protein CTD PMID:33545341 PMID:35724838 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DDIT4 DNA damage inducible transcript 4 increases expression EXP diethyl maleate results in increased expression of DDIT4 mRNA CTD PMID:33545341 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
JBrowse link
G DDIT4L DNA damage inducible transcript 4 like increases expression ISO diethyl maleate results in increased expression of DDIT4L mRNA CTD PMID:25270620 NCBI chr 4:100,185,870...100,190,468
Ensembl chr 4:100,185,870...100,190,782
JBrowse link
G DDX60 DExD/H-box helicase 60 decreases expression ISO diethyl maleate results in decreased expression of DDX60 mRNA CTD PMID:21161181 NCBI chr 4:168,216,294...168,325,979
Ensembl chr 4:168,216,291...168,318,883
JBrowse link
G DHX58 DExH-box helicase 58 decreases expression ISO diethyl maleate results in decreased expression of DHX58 mRNA CTD PMID:21161181 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 increases expression EXP diethyl maleate results in increased expression of DNAJB1 mRNA CTD PMID:33545341 PMID:34480604 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391
JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 increases expression EXP diethyl maleate results in increased expression of DNAJB4 mRNA CTD PMID:33545341 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964
JBrowse link
G DNMBP dynamin binding protein decreases expression ISO diethyl maleate results in decreased expression of DNMBP mRNA CTD PMID:21161181 NCBI chr10:99,875,571...100,009,947
Ensembl chr10:99,875,577...100,009,947
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 decreases reduction ISO diethyl maleate results in decreased reduction of DPYSL2 protein CTD PMID:19843705 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
JBrowse link
G DTX3L deltex E3 ubiquitin ligase 3L decreases expression ISO diethyl maleate results in decreased expression of DTX3L mRNA CTD PMID:21161181 NCBI chr 3:122,564,338...122,575,203
Ensembl chr 3:122,564,338...122,575,203
JBrowse link
G DUS3L dihydrouridine synthase 3 like decreases expression ISO diethyl maleate results in decreased expression of DUS3L mRNA CTD PMID:25270620 NCBI chr19:5,785,140...5,791,163
Ensembl chr19:5,784,832...5,791,225
JBrowse link
G DUSP6 dual specificity phosphatase 6 increases expression EXP diethyl maleate results in increased expression of DUSP6 mRNA CTD PMID:33545341 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501
JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase decreases expression ISO diethyl maleate results in decreased expression of EEF2K mRNA CTD PMID:21161181 NCBI chr16:22,206,278...22,288,738
Ensembl chr16:22,206,278...22,288,738
JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 increases expression EXP diethyl maleate results in increased expression of EGLN3 mRNA CTD PMID:34480604 NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774
JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 decreases expression ISO diethyl maleate results in decreased expression of EIF2AK2 mRNA CTD PMID:21161181 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522
JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) increases expression ISO diethyl maleate results in increased expression of ENTPD5 mRNA CTD PMID:25270620 NCBI chr14:73,955,329...74,019,288
Ensembl chr14:73,958,010...74,019,399
JBrowse link
G ERAS ES cell expressed Ras decreases expression ISO diethyl maleate results in decreased expression of ERAS mRNA CTD PMID:25270620 NCBI chr  X:48,826,513...48,829,869
Ensembl chr  X:48,826,513...48,830,138
JBrowse link
G ERCC6L ERCC excision repair 6 like, spindle assembly checkpoint helicase increases expression ISO diethyl maleate results in increased expression of ERCC6L mRNA CTD PMID:21161181 NCBI chr  X:72,204,665...72,239,027
Ensembl chr  X:72,204,657...72,239,027
JBrowse link
G EXO1 exonuclease 1 increases expression ISO diethyl maleate results in increased expression of EXO1 mRNA CTD PMID:21161181 NCBI chr 1:241,847,986...241,889,939
Ensembl chr 1:241,847,967...241,895,148
JBrowse link
G FABP1 fatty acid binding protein 1 increases expression ISO diethyl maleate results in increased expression of FABP1 protein CTD PMID:21161181 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
JBrowse link
G FABP7 fatty acid binding protein 7 decreases expression ISO diethyl maleate results in decreased expression of FABP7 mRNA CTD PMID:21161181 NCBI chr 6:122,749,201...122,784,074
Ensembl chr 6:122,779,716...122,784,074
JBrowse link
G FAH fumarylacetoacetate hydrolase affects expression EXP diethyl maleate affects the expression of FAH mRNA CTD PMID:34480604 NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946
JBrowse link
G FAM83D family with sequence similarity 83 member D increases expression EXP diethyl maleate results in increased expression of FAM83D mRNA CTD PMID:33545341 NCBI chr20:38,926,417...38,953,106
Ensembl chr20:38,926,312...38,953,106
JBrowse link
G FASN fatty acid synthase decreases expression ISO diethyl maleate results in decreased expression of FASN mRNA CTD PMID:21161181 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G FBN1 fibrillin 1 decreases expression ISO diethyl maleate results in decreased expression of FBN1 mRNA CTD PMID:21161181 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,313...48,645,721
JBrowse link
G FBP1 fructose-bisphosphatase 1 decreases expression ISO diethyl maleate results in decreased expression of FBP1 protein CTD PMID:21161181 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249
JBrowse link
G FGF17 fibroblast growth factor 17 decreases expression ISO diethyl maleate results in decreased expression of FGF17 mRNA CTD PMID:25270620 NCBI chr 8:22,039,672...22,048,809
Ensembl chr 8:22,042,398...22,048,809
JBrowse link
G FGG fibrinogen gamma chain decreases expression ISO diethyl maleate results in decreased expression of FGG mRNA CTD PMID:25270620 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase decreases expression ISO diethyl maleate results in decreased expression of FGR mRNA CTD PMID:21161181 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185
JBrowse link
G FNDC3B fibronectin type III domain containing 3B decreases expression ISO diethyl maleate results in decreased expression of FNDC3B mRNA CTD PMID:25270620 NCBI chr 3:172,039,578...172,401,669
Ensembl chr 3:172,039,578...172,401,669
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO
EXP
diethyl maleate results in increased expression of FOS mRNA CTD PMID:10915739 PMID:33545341 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOXO1 forkhead box O1 multiple interactions EXP diethyl maleate inhibits the reaction [INS protein affects the localization of and results in increased phosphorylation of FOXO1 protein] CTD PMID:30261343 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
JBrowse link
G FOXO3 forkhead box O3 increases expression EXP diethyl maleate results in increased expression of FOXO3 mRNA CTD PMID:33545341 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G FSTL3 follistatin like 3 increases expression EXP diethyl maleate results in increased expression of FSTL3 mRNA CTD PMID:33545341 NCBI chr19:676,392...683,385
Ensembl chr19:676,392...683,392
JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP
ISO
diethyl maleate results in decreased expression of G6PC1 mRNA CTD PMID:25270620 PMID:30261343 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase increases activity
increases expression
ISO
EXP
diethyl maleate results in increased activity of G6PD protein
diethyl maleate results in increased expression of G6PD mRNA
CTD PMID:3099627 PMID:30261343 PMID:33545341 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GAB1 GRB2 associated binding protein 1 decreases expression ISO diethyl maleate results in decreased expression of GAB1 mRNA CTD PMID:25270620 NCBI chr 4:143,336,876...143,474,565
Ensembl chr 4:143,336,876...143,474,565
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP diethyl maleate results in increased expression of GADD45A mRNA CTD PMID:33545341 PMID:34480604 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma increases expression EXP diethyl maleate results in increased expression of GADD45G mRNA CTD PMID:33545341 NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase increases reduction ISO diethyl maleate results in increased reduction of GAPDH protein CTD PMID:19843705 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G GBA2 glucosylceramidase beta 2 decreases expression ISO diethyl maleate results in decreased expression of GBA2 mRNA CTD PMID:25270620 NCBI chr 9:35,736,866...35,749,228
Ensembl chr 9:35,736,866...35,749,228
JBrowse link
G GBP2 guanylate binding protein 2 decreases expression ISO diethyl maleate results in decreased expression of GBP2 mRNA CTD PMID:21161181 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases activity
increases expression
ISO
EXP
diethyl maleate results in increased activity of GCLC protein
diethyl maleate results in increased expression of GCLC mRNA; diethyl maleate results in increased expression of GCLC protein
CTD PMID:10915739 PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 More... NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression ISO
EXP
diethyl maleate results in increased expression of GCLM mRNA; diethyl maleate results in increased expression of GCLM protein CTD PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 PMID:33545341 More... NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression EXP diethyl maleate results in increased expression of GCNT3 mRNA CTD PMID:33545341 NCBI chr15:59,549,039...59,622,723
Ensembl chr15:59,594,875...59,640,239
JBrowse link
G GDF15 growth differentiation factor 15 increases expression EXP diethyl maleate results in increased expression of GDF15 mRNA CTD PMID:33545341 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176
JBrowse link
G GDF9 growth differentiation factor 9 increases expression EXP diethyl maleate results in increased expression of GDF9 mRNA CTD PMID:33545341 NCBI chr 5:132,861,185...132,866,651
Ensembl chr 5:132,861,181...132,866,884
JBrowse link
G GFOD1 Gfo/Idh/MocA-like oxidoreductase domain containing 1 increases expression EXP diethyl maleate results in increased expression of GFOD1 mRNA CTD PMID:33545341 NCBI chr 6:13,357,830...13,487,600
Ensembl chr 6:13,357,830...13,487,662
JBrowse link
G GLUL glutamate-ammonia ligase decreases expression ISO diethyl maleate results in decreased expression of GLUL mRNA CTD PMID:25270620 NCBI chr 1:182,378,098...182,391,790
Ensembl chr 1:182,378,098...182,392,206
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 decreases expression ISO diethyl maleate results in decreased expression of GOT2 protein CTD PMID:21161181 NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
JBrowse link
G GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 decreases expression ISO diethyl maleate results in decreased expression of GPIHBP1 mRNA CTD PMID:25270620 NCBI chr 8:143,213,218...143,217,170
Ensembl chr 8:143,213,218...143,217,170
JBrowse link
G GPX2 glutathione peroxidase 2 affects expression EXP diethyl maleate affects the expression of GPX2 mRNA CTD PMID:34480604 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression ISO diethyl maleate results in decreased expression of GRIA3 mRNA CTD PMID:21161181 NCBI chr  X:123,184,278...123,490,915
Ensembl chr  X:123,184,153...123,490,915
JBrowse link
G GSN gelsolin decreases reduction ISO diethyl maleate results in decreased reduction of GSN protein CTD PMID:19843705 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843
JBrowse link
G GSR glutathione-disulfide reductase increases expression ISO diethyl maleate results in increased expression of GSR mRNA CTD PMID:25270620 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSS glutathione synthetase increases expression ISO diethyl maleate results in increased expression of GSS mRNA CTD PMID:10978506 NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
JBrowse link
G GSTA1 glutathione S-transferase alpha 1 affects expression EXP diethyl maleate affects the expression of GSTA1 mRNA CTD PMID:34480604 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860
JBrowse link
G GSTA5 glutathione S-transferase alpha 5 increases expression ISO diethyl maleate results in increased expression of GSTA5 protein CTD PMID:9794803 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843
JBrowse link
G GSTK1 glutathione S-transferase kappa 1 multiple interactions ISO [diethyl maleate results in decreased abundance of Glutathione] which results in decreased expression of GSTK1 mRNA CTD PMID:22564015 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
JBrowse link
G GSTM1 glutathione S-transferase mu 1 decreases expression ISO diethyl maleate results in decreased expression of GSTM1 protein CTD PMID:21161181 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTO1 glutathione S-transferase omega 1 increases expression ISO diethyl maleate results in increased expression of GSTO1 mRNA CTD PMID:25270620 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
JBrowse link
G GSTP1 glutathione S-transferase pi 1 increases expression ISO diethyl maleate results in increased expression of GSTP1 protein CTD PMID:9794803 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 increases expression ISO diethyl maleate results in increased expression of GSTT1 protein CTD PMID:9794803
G GTSE1 G2 and S-phase expressed 1 increases expression ISO diethyl maleate results in increased expression of GTSE1 mRNA CTD PMID:21161181 NCBI chr22:46,296,870...46,330,810
Ensembl chr22:46,296,870...46,330,810
JBrowse link
G H2AZ2 H2A.Z variant histone 2 increases expression EXP diethyl maleate results in increased expression of H2AZ2 mRNA CTD PMID:33545341 NCBI chr 7:44,826,889...44,848,126
Ensembl chr 7:44,826,791...44,848,087
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase increases expression ISO diethyl maleate results in increased expression of H6PD mRNA CTD PMID:25270620 NCBI chr 1:9,234,774...9,271,337
Ensembl chr 1:9,234,774...9,271,337
JBrowse link
G HAMP hepcidin antimicrobial peptide increases expression EXP diethyl maleate results in increased expression of HAMP mRNA CTD PMID:33545341 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
JBrowse link
G HELB DNA helicase B decreases expression ISO diethyl maleate results in decreased expression of HELB mRNA CTD PMID:25270620 NCBI chr12:66,302,493...66,343,643
Ensembl chr12:66,302,493...66,343,643
JBrowse link
G HES6 hes family bHLH transcription factor 6 decreases expression ISO diethyl maleate results in decreased expression of HES6 mRNA CTD PMID:21161181 NCBI chr 2:238,238,267...238,240,038
Ensembl chr 2:238,238,267...238,240,662
JBrowse link
G HJURP Holliday junction recognition protein increases expression ISO diethyl maleate results in increased expression of HJURP mRNA CTD PMID:21161181 NCBI chr 2:233,836,702...233,854,535
Ensembl chr 2:233,833,416...233,854,566
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP
ISO
diethyl maleate results in increased expression of HMOX1 mRNA; diethyl maleate results in increased expression of HMOX1 protein CTD PMID:20491607 PMID:25270620 PMID:30261343 PMID:33545341 PMID:34480604 More... NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 decreases reduction ISO diethyl maleate results in decreased reduction of HNRNPH1 protein CTD PMID:19843705 NCBI chr 5:179,614,178...179,634,784
Ensembl chr 5:179,614,178...179,634,784
JBrowse link
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 increases expression EXP diethyl maleate results in increased expression of HSD17B10 mRNA CTD PMID:33545341 NCBI chr  X:53,431,258...53,434,376
Ensembl chr  X:53,431,258...53,434,370
JBrowse link
G HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 decreases expression ISO diethyl maleate results in decreased expression of HSD17B2 mRNA CTD PMID:21161181 NCBI chr16:82,035,253...82,098,534
Ensembl chr16:82,035,004...82,098,534
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression EXP diethyl maleate results in increased expression of HSPA1B mRNA CTD PMID:33545341 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like increases expression EXP diethyl maleate results in increased expression of HSPA1L mRNA CTD PMID:33545341 NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,283
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 decreases reduction ISO diethyl maleate results in decreased reduction of HSPA5 protein CTD PMID:19843705 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP diethyl maleate results in increased expression of HSPA6 mRNA CTD PMID:33545341 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 increases reduction ISO diethyl maleate results in increased reduction of HSPA8 protein CTD PMID:19843705 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G HTATIP2 HIV-1 Tat interactive protein 2 increases expression ISO diethyl maleate results in increased expression of HTATIP2 mRNA CTD PMID:25270620 NCBI chr11:20,363,714...20,383,782
Ensembl chr11:20,363,685...20,383,782
JBrowse link
G HYCC2 hyccin PI4KA lipid kinase complex subunit 2 decreases expression ISO diethyl maleate results in decreased expression of HYCC2 mRNA CTD PMID:21161181 NCBI chr 2:200,973,718...201,071,671
Ensembl chr 2:200,973,718...201,071,671
JBrowse link
G ICAM1 intercellular adhesion molecule 1 decreases expression
multiple interactions
ISO
EXP
diethyl maleate results in decreased expression of ICAM1 mRNA
diethyl maleate inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; NFE2L2 protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]
CTD PMID:25270620 PMID:35724838 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G ID3 inhibitor of DNA binding 3 decreases expression ISO diethyl maleate results in decreased expression of ID3 mRNA CTD PMID:25270620 NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501
JBrowse link
G ID4 inhibitor of DNA binding 4 decreases expression ISO diethyl maleate results in decreased expression of ID4 mRNA CTD PMID:25270620 NCBI chr 6:19,837,370...19,842,197
Ensembl chr 6:19,837,370...19,842,197
JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 decreases expression ISO diethyl maleate results in decreased expression of IFIT3 mRNA CTD PMID:21161181 NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473
JBrowse link
G IFRD1 interferon related developmental regulator 1 increases expression EXP diethyl maleate results in increased expression of IFRD1 mRNA CTD PMID:33545341 NCBI chr 7:112,423,174...112,477,203
Ensembl chr 7:112,422,887...112,481,017
JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO diethyl maleate results in decreased expression of IKBKE mRNA CTD PMID:25270620 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma increases expression ISO diethyl maleate results in increased expression of IKBKG mRNA CTD PMID:25270620 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046
JBrowse link
G IL10 interleukin 10 increases secretion EXP diethyl maleate results in increased secretion of IL10 protein CTD PMID:31958493 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL18 interleukin 18 increases expression EXP diethyl maleate results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1A interleukin 1 alpha multiple interactions EXP diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP diethyl maleate inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; diethyl maleate inhibits the reaction [IL1B protein affects the localization of RELA protein]; diethyl maleate inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; diethyl maleate inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein] CTD PMID:35724838 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1R1 interleukin 1 receptor type 1 affects expression EXP diethyl maleate affects the expression of IL1R1 mRNA CTD PMID:34480604 NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874
JBrowse link
G IL4 interleukin 4 multiple interactions EXP [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein CTD PMID:31958493 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G INHBB inhibin subunit beta B decreases expression ISO diethyl maleate results in decreased expression of INHBB mRNA CTD PMID:25270620 NCBI chr 2:120,346,136...120,351,803
Ensembl chr 2:120,346,136...120,351,803
JBrowse link
G INMT indolethylamine N-methyltransferase decreases expression ISO diethyl maleate results in decreased expression of INMT mRNA CTD PMID:21161181 NCBI chr 7:30,752,135...30,757,602
Ensembl chr 7:30,697,985...30,757,602
JBrowse link
G INS insulin multiple interactions EXP diethyl maleate inhibits the reaction [INS protein affects the localization of and results in increased phosphorylation of FOXO1 protein] CTD PMID:30261343 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G INTS7 integrator complex subunit 7 decreases expression ISO diethyl maleate results in decreased expression of INTS7 mRNA CTD PMID:25270620 NCBI chr 1:211,940,403...212,035,557
Ensembl chr 1:211,940,399...212,035,557
JBrowse link
G IRF7 interferon regulatory factor 7 decreases expression ISO diethyl maleate results in decreased expression of IRF7 mRNA CTD PMID:21161181 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983
JBrowse link
G IRF9 interferon regulatory factor 9 decreases expression ISO diethyl maleate results in decreased expression of IRF9 mRNA CTD PMID:21161181 NCBI chr14:24,161,265...24,166,565
Ensembl chr14:24,161,234...24,168,043
JBrowse link
G IRGM immunity related GTPase M decreases expression ISO diethyl maleate results in decreased expression of IRGM mRNA CTD PMID:21161181 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736
JBrowse link
G ITGAL integrin subunit alpha L decreases expression ISO diethyl maleate results in decreased expression of ITGAL mRNA CTD PMID:21161181 NCBI chr16:30,472,742...30,523,185
Ensembl chr16:30,472,658...30,523,567
JBrowse link
G ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 decreases expression ISO diethyl maleate results in decreased expression of ITIH3 mRNA CTD PMID:25270620 NCBI chr 3:52,794,796...52,808,797
Ensembl chr 3:52,794,768...52,808,799
JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 decreases expression ISO diethyl maleate results in decreased expression of ITIH4 mRNA CTD PMID:25270620 NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688
JBrowse link
G JAM3 junctional adhesion molecule 3 decreases expression ISO diethyl maleate results in decreased expression of JAM3 mRNA CTD PMID:21161181 NCBI chr11:134,069,072...134,152,001
Ensembl chr11:134,069,071...134,152,001
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
increases phosphorylation
ISO
EXP
pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]
diethyl maleate results in increased expression of JUN protein modified form
pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of JUN protein modified form]
diethyl maleate results in increased expression of JUN mRNA
CTD PMID:10915739 PMID:12774022 PMID:30261343 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 decreases expression ISO diethyl maleate results in decreased expression of KCNE3 mRNA CTD PMID:25270620 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729
JBrowse link
G KEAP1 kelch like ECH associated protein 1 increases expression EXP diethyl maleate results in increased expression of KEAP1 mRNA; diethyl maleate results in increased expression of KEAP1 protein CTD PMID:27358234 PMID:33545341 PMID:34480604 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KHDRBS3 KH RNA binding domain containing, signal transduction associated 3 increases expression EXP diethyl maleate results in increased expression of KHDRBS3 mRNA CTD PMID:33545341 NCBI chr 8:135,457,456...135,656,516
Ensembl chr 8:135,457,456...135,656,722
JBrowse link
G KIFC1 kinesin family member C1 increases expression ISO diethyl maleate results in increased expression of KIFC1 mRNA CTD PMID:21161181 NCBI chr 6:33,391,461...33,409,896
Ensembl chr 6:33,391,823...33,409,896
JBrowse link
G KLF10 KLF transcription factor 10 decreases expression ISO diethyl maleate results in decreased expression of KLF10 mRNA CTD PMID:21161181 PMID:25270620 NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725
JBrowse link
G KRT75 keratin 75 increases reduction ISO diethyl maleate results in increased reduction of KRT75 protein CTD PMID:19843705 NCBI chr12:52,424,070...52,434,371
Ensembl chr12:52,424,070...52,434,371
JBrowse link
G LAMA1 laminin subunit alpha 1 decreases expression ISO diethyl maleate results in decreased expression of LAMA1 mRNA CTD PMID:25270620 NCBI chr18:6,941,742...7,117,797
Ensembl chr18:6,941,742...7,117,797
JBrowse link
G LANCL2 LanC like glutathione S-transferase 2 decreases expression ISO diethyl maleate results in decreased expression of LANCL2 mRNA CTD PMID:25270620 NCBI chr 7:55,365,337...55,433,737
Ensembl chr 7:55,365,337...55,433,737
JBrowse link
G LDLR low density lipoprotein receptor decreases expression ISO diethyl maleate results in decreased expression of LDLR mRNA CTD PMID:21161181 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
JBrowse link
G LEPR leptin receptor decreases expression ISO diethyl maleate results in decreased expression of LEPR mRNA CTD PMID:21161181 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G LGALS3BP galectin 3 binding protein decreases expression ISO diethyl maleate results in decreased expression of LGALS3BP mRNA CTD PMID:21161181 NCBI chr17:78,971,255...78,979,923
Ensembl chr17:78,971,238...78,979,947
JBrowse link
G LMNB1 lamin B1 increases expression ISO diethyl maleate results in increased expression of LMNB1 mRNA CTD PMID:21161181 NCBI chr 5:126,776,623...126,837,020
Ensembl chr 5:126,776,623...126,837,020
JBrowse link
G LMO7 LIM domain 7 decreases expression ISO diethyl maleate results in decreased expression of LMO7 mRNA CTD PMID:21161181 NCBI chr13:75,620,434...75,859,870
Ensembl chr13:75,620,434...75,859,870
JBrowse link
G LRIG3 leucine rich repeats and immunoglobulin like domains 3 decreases expression ISO diethyl maleate results in decreased expression of LRIG3 mRNA CTD PMID:21161181 NCBI chr12:58,872,155...58,920,504
Ensembl chr12:58,872,149...58,920,504
JBrowse link
G LRRN4 leucine rich repeat neuronal 4 increases expression ISO diethyl maleate results in increased expression of LRRN4 mRNA CTD PMID:21161181 NCBI chr20:6,040,546...6,054,060
Ensembl chr20:6,040,546...6,054,060
JBrowse link
G LRTM2 leucine rich repeats and transmembrane domains 2 decreases expression ISO diethyl maleate results in decreased expression of LRTM2 mRNA CTD PMID:21161181 NCBI chr12:1,820,565...1,836,753
Ensembl chr12:1,820,267...1,836,753
JBrowse link
G LTC4S leukotriene C4 synthase decreases expression ISO diethyl maleate results in decreased expression of LTC4S mRNA CTD PMID:21161181 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647
JBrowse link
G LUM lumican decreases expression ISO diethyl maleate results in decreased expression of LUM mRNA CTD PMID:21161181 NCBI chr12:91,102,629...91,111,494
Ensembl chr12:91,102,629...91,111,494
JBrowse link
G MAFF MAF bZIP transcription factor F increases expression EXP diethyl maleate results in increased expression of MAFF mRNA CTD PMID:20491607 PMID:33545341 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507
JBrowse link
G MAFG MAF bZIP transcription factor G increases expression EXP diethyl maleate results in increased expression of MAFG mRNA CTD PMID:33545341 PMID:34480604 NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735
JBrowse link
G MAOA monoamine oxidase A increases expression ISO diethyl maleate results in increased expression of MAOA mRNA CTD PMID:25270620 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817
JBrowse link
G MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1 like increases expression EXP diethyl maleate results in increased expression of MAPK1IP1L mRNA CTD PMID:33545341 NCBI chr14:55,051,647...55,070,194
Ensembl chr14:55,051,647...55,070,194
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions
increases expression
EXP pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of MAPK8 protein modified form] CTD PMID:30261343 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 increases expression
multiple interactions
EXP diethyl maleate results in increased expression of MAPK9 protein modified form
pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of MAPK9 protein modified form]
CTD PMID:30261343 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MARVELD1 MARVEL domain containing 1 decreases expression ISO diethyl maleate results in decreased expression of MARVELD1 mRNA CTD PMID:21161181 NCBI chr10:97,713,730...97,718,150
Ensembl chr10:97,713,173...97,718,150
JBrowse link
G MBOAT7 membrane bound O-acyltransferase domain containing 7 increases expression EXP diethyl maleate results in increased expression of MBOAT7 mRNA CTD PMID:33545341 NCBI chr19:54,173,415...54,189,580
Ensembl chr19:54,173,412...54,189,882
JBrowse link
G MCM10 minichromosome maintenance 10 replication initiation factor increases expression ISO diethyl maleate results in increased expression of MCM10 mRNA CTD PMID:21161181 NCBI chr10:13,161,558...13,211,110
Ensembl chr10:13,161,558...13,211,110
JBrowse link
G MCM4 minichromosome maintenance complex component 4 increases expression ISO diethyl maleate results in increased expression of MCM4 mRNA CTD PMID:21161181 NCBI chr 8:47,960,941...47,978,160
Ensembl chr 8:47,960,185...47,978,160
JBrowse link
G ME1 malic enzyme 1 increases expression ISO diethyl maleate results in increased expression of ME1 mRNA CTD PMID:25270620 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
JBrowse link
G MFAP4 microfibril associated protein 4 decreases expression ISO diethyl maleate results in decreased expression of MFAP4 mRNA CTD PMID:21161181 NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase decreases activity EXP diethyl maleate results in decreased activity of MGMT protein CTD PMID:16950796 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G MKI67 marker of proliferation Ki-67 increases expression ISO diethyl maleate results in increased expression of MKI67 mRNA CTD PMID:21161181 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
JBrowse link
G MKNK2 MAPK interacting serine/threonine kinase 2 decreases expression ISO diethyl maleate results in decreased expression of MKNK2 mRNA CTD PMID:21161181 NCBI chr19:2,037,471...2,051,244
Ensembl chr19:2,037,465...2,051,244
JBrowse link
G MMP1 matrix metallopeptidase 1 increases expression EXP diethyl maleate results in increased expression of MMP1 mRNA CTD PMID:33545341 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP12 matrix metallopeptidase 12 increases expression ISO diethyl maleate results in increased expression of MMP12 mRNA CTD PMID:10216232 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G MMP2 matrix metallopeptidase 2 decreases expression ISO diethyl maleate results in decreased expression of MMP2 mRNA CTD PMID:21161181 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP3 matrix metallopeptidase 3 increases expression EXP diethyl maleate results in increased expression of MMP3 mRNA CTD PMID:33545341 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MPZL1 myelin protein zero like 1 decreases expression EXP diethyl maleate results in decreased expression of MPZL1 mRNA CTD PMID:34480604 NCBI chr 1:167,721,982...167,791,919
Ensembl chr 1:167,721,192...167,791,919
JBrowse link
G MSN moesin increases reduction ISO diethyl maleate results in increased reduction of MSN protein CTD PMID:19843705 NCBI chr  X:65,588,377...65,741,931
Ensembl chr  X:65,588,377...65,741,931
JBrowse link
G MT1A metallothionein 1A increases expression EXP diethyl maleate results in increased expression of MT1A mRNA CTD PMID:20491607 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT2A metallothionein 2A increases expression EXP diethyl maleate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MX1 MX dynamin like GTPase 1 decreases expression ISO diethyl maleate results in decreased expression of MX1 mRNA CTD PMID:21161181 NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071
JBrowse link
G MX2 MX dynamin like GTPase 2 decreases expression ISO diethyl maleate results in decreased expression of MX2 mRNA CTD PMID:21161181 NCBI chr21:41,362,027...41,409,393
Ensembl chr21:41,361,999...41,409,393
JBrowse link
G MYBL2 MYB proto-oncogene like 2 increases expression ISO diethyl maleate results in increased expression of MYBL2 mRNA CTD PMID:21161181 NCBI chr20:43,667,114...43,716,482
Ensembl chr20:43,667,019...43,716,495
JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor decreases expression ISO diethyl maleate results in decreased expression of MYCN mRNA CTD PMID:25270620 NCBI chr 2:15,940,550...15,947,004
Ensembl chr 2:15,940,550...15,947,007
JBrowse link
G NAT8 N-acetyltransferase 8 (putative) decreases expression ISO diethyl maleate results in decreased expression of NAT8 mRNA CTD PMID:21161181 NCBI chr 2:73,640,723...73,642,422
Ensembl chr 2:73,640,723...73,642,422
JBrowse link
G NCAPH non-SMC condensin I complex subunit H increases expression ISO diethyl maleate results in increased expression of NCAPH mRNA CTD PMID:21161181 NCBI chr 2:96,335,766...96,377,091
Ensembl chr 2:96,335,766...96,377,091
JBrowse link
G NDRG1 N-myc downstream regulated 1 increases expression EXP diethyl maleate results in increased expression of NDRG1 mRNA CTD PMID:33545341 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects localization
increases activity
increases expression
multiple interactions
decreases response to substance
ISO
EXP
diethyl maleate affects the localization of NFE2L2 protein
diethyl maleate results in increased activity of NFE2L2 protein
diethyl maleate results in increased expression of NFE2L2 protein
[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein; diethyl maleate binds to and results in increased activity of NFE2L2 protein; diethyl maleate promotes the reaction [NFE2L2 protein binds to SMPD1 promoter]; diethyl maleate results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SMPD1 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; NFE2L2 protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]; RELA protein inhibits the reaction [diethyl maleate results in increased expression of NFE2L2 protein]; RELA protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]; TNFAIP3 protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]
NFE2L2 results in decreased susceptibility to diethyl maleate
NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]
CTD PMID:12235164 PMID:20806931 PMID:21465251 PMID:22003191 PMID:25762726 More... NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO
EXP
diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]
diethyl maleate inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; diethyl maleate inhibits the reaction [TNF protein affects the localization of NFKBIA protein]
CTD PMID:12774022 PMID:35724838 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 decreases expression ISO diethyl maleate results in decreased expression of NHERF1 mRNA CTD PMID:21161181 NCBI chr17:74,748,628...74,769,353
Ensembl chr17:74,748,628...74,769,353
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
Acetylcysteine inhibits the reaction [diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate]
CTD PMID:7532384 PMID:9918918 PMID:12774022 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOTCH1 notch receptor 1 increases expression EXP diethyl maleate results in increased expression of NOTCH1 mRNA CTD PMID:33545341 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression EXP
ISO
diethyl maleate results in increased expression of NQO1 mRNA CTD PMID:20491607 PMID:25270620 PMID:33545341 PMID:34480604 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 decreases expression ISO diethyl maleate results in decreased expression of NR0B2 mRNA CTD PMID:21161181 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 decreases expression ISO diethyl maleate results in decreased expression of NR1D1 mRNA CTD PMID:21161181 NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589
JBrowse link
G NREP neuronal regeneration related protein decreases expression ISO diethyl maleate results in decreased expression of NREP mRNA CTD PMID:21161181 NCBI chr 5:111,728,802...111,976,932
Ensembl chr 5:111,662,621...111,997,464
JBrowse link
G NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor decreases expression ISO diethyl maleate results in decreased expression of NSMF mRNA CTD PMID:25270620 NCBI chr 9:137,447,570...137,459,334
Ensembl chr 9:137,447,570...137,459,334
JBrowse link
G NTF3 neurotrophin 3 decreases expression ISO diethyl maleate results in decreased expression of NTF3 mRNA CTD PMID:21161181 NCBI chr12:5,430,332...5,495,299
Ensembl chr12:5,432,108...5,521,536
JBrowse link
G NUP153 nucleoporin 153 multiple interactions
affects localization
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; diethyl maleate results in increased phosphorylation of and results in increased O-linked glycosylation of NUP153 protein CTD PMID:20041180 NCBI chr 6:17,615,037...17,706,925
Ensembl chr 6:17,615,035...17,706,925
JBrowse link
G NUP88 nucleoporin 88 multiple interactions
affects localization
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] affects the reaction [diethyl maleate affects the localization of NUP88 protein]; diethyl maleate results in increased phosphorylation of and results in increased glycosylation of NUP88 protein CTD PMID:20041180 NCBI chr17:5,384,833...5,419,662
Ensembl chr17:5,359,668...5,420,164
JBrowse link
G OAF out at first homolog decreases expression ISO diethyl maleate results in decreased expression of OAF mRNA CTD PMID:21161181 NCBI chr11:120,211,032...120,230,334
Ensembl chr11:120,211,032...120,230,334
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase multiple interactions ISO [diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of OGG1 mRNA CTD PMID:22564015 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G ORC1 origin recognition complex subunit 1 increases expression ISO diethyl maleate results in increased expression of ORC1 mRNA CTD PMID:21161181 NCBI chr 1:52,372,829...52,409,503
Ensembl chr 1:52,372,829...52,404,423
JBrowse link
G OSGIN1 oxidative stress induced growth inhibitor 1 increases expression EXP diethyl maleate results in increased expression of OSGIN1 mRNA CTD PMID:33545341 NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332
JBrowse link
G P2RX7 purinergic receptor P2X 7 decreases expression ISO diethyl maleate results in decreased expression of P2RX7 mRNA CTD PMID:21161181 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage EXP diethyl maleate results in increased cleavage of PARP1 protein CTD PMID:21105742 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PBLD phenazine biosynthesis like protein domain containing decreases expression ISO diethyl maleate results in decreased expression of PBLD protein CTD PMID:21161181 NCBI chr10:68,282,660...68,332,928
Ensembl chr10:68,282,660...68,333,049
JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression EXP diethyl maleate results in decreased expression of PCNA mRNA CTD PMID:11875189 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PDLIM2 PDZ and LIM domain 2 decreases expression ISO diethyl maleate results in decreased expression of PDLIM2 mRNA CTD PMID:21161181 NCBI chr 8:22,578,741...22,598,026
Ensembl chr 8:22,578,279...22,598,025
JBrowse link
G PDRG1 p53 and DNA damage regulated 1 increases expression ISO diethyl maleate results in increased expression of PDRG1 mRNA CTD PMID:25270620 NCBI chr20:31,944,337...31,952,046
Ensembl chr20:31,944,337...31,952,046
JBrowse link
G PER2 period circadian regulator 2 decreases expression ISO diethyl maleate results in decreased expression of PER2 mRNA CTD PMID:21161181 NCBI chr 2:238,244,044...238,300,065
Ensembl chr 2:238,244,044...238,290,102
JBrowse link
G PER3 period circadian regulator 3 decreases expression ISO diethyl maleate results in decreased expression of PER3 mRNA CTD PMID:21161181 NCBI chr 1:7,784,291...7,845,177
Ensembl chr 1:7,784,291...7,845,177
JBrowse link
G PGD phosphogluconate dehydrogenase increases activity ISO diethyl maleate results in increased activity of PGD protein CTD PMID:3099627 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511
JBrowse link
G PGRMC1 progesterone receptor membrane component 1 increases expression ISO diethyl maleate results in increased expression of PGRMC1 mRNA CTD PMID:25270620 NCBI chr  X:119,236,285...119,244,466
Ensembl chr  X:119,236,245...119,244,466
JBrowse link
G PIR pirin increases expression ISO diethyl maleate results in increased expression of PIR mRNA CTD PMID:25270620 NCBI chr  X:15,384,799...15,493,333
Ensembl chr  X:15,384,799...15,493,564
JBrowse link
G PKLR pyruvate kinase L/R decreases expression ISO diethyl maleate results in decreased expression of PKLR mRNA CTD PMID:21161181 NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438
JBrowse link
G PLAT plasminogen activator, tissue type increases expression
decreases expression
ISO diethyl maleate results in increased expression of PLAT mRNA
diethyl maleate results in decreased expression of PLAT mRNA
CTD PMID:21161181 PMID:25270620 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLEK pleckstrin decreases expression ISO diethyl maleate results in decreased expression of PLEK mRNA CTD PMID:21161181 NCBI chr 2:68,365,282...68,397,453
Ensembl chr 2:68,365,282...68,397,453
JBrowse link
G PLEKHM1 pleckstrin homology and RUN domain containing M1 increases expression EXP diethyl maleate results in increased expression of PLEKHM1 mRNA CTD PMID:33545341 NCBI chr17:45,434,209...45,490,721
Ensembl chr17:45,435,900...45,490,758
JBrowse link
G PLIN2 perilipin 2 increases expression EXP diethyl maleate results in increased expression of PLIN2 mRNA CTD PMID:33545341 NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
JBrowse link
G PLK1 polo like kinase 1 increases expression EXP diethyl maleate results in increased expression of PLK1 mRNA CTD PMID:33545341 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367
JBrowse link
G PLK3 polo like kinase 3 increases expression EXP diethyl maleate results in increased expression of PLK3 mRNA CTD PMID:33545341 NCBI chr 1:44,800,377...44,805,990
Ensembl chr 1:44,800,377...44,805,990
JBrowse link
G POU5F1 POU class 5 homeobox 1 increases expression EXP diethyl maleate results in increased expression of POU5F1 mRNA CTD PMID:33545341 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions
decreases activity
ISO diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol inhibits the reaction [diethyl maleate results in decreased activity of PPARA protein]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate results in decreased activity of PPARA protein] CTD PMID:17134953 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARGC1B PPARG coactivator 1 beta decreases expression ISO diethyl maleate results in decreased expression of PPARGC1B mRNA CTD PMID:21161181 NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022
JBrowse link
G PPP1R3B protein phosphatase 1 regulatory subunit 3B decreases expression ISO diethyl maleate results in decreased expression of PPP1R3B mRNA CTD PMID:21161181 NCBI chr 8:9,136,255...9,151,539
Ensembl chr 8:9,136,255...9,151,574
JBrowse link
G PPP1R3C protein phosphatase 1 regulatory subunit 3C decreases expression ISO diethyl maleate results in decreased expression of PPP1R3C mRNA CTD PMID:21161181 NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071
JBrowse link
G PRDM14 PR/SET domain 14 decreases expression ISO diethyl maleate results in decreased expression of PRDM14 mRNA CTD PMID:25270620 NCBI chr 8:70,051,651...70,071,252
Ensembl chr 8:70,051,651...70,071,693
JBrowse link
G PRDX1 peroxiredoxin 1 increases expression ISO
EXP
diethyl maleate results in increased expression of PRDX1 mRNA CTD PMID:9506838 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
JBrowse link
G PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 decreases expression ISO diethyl maleate results in decreased expression of PRKAB1 mRNA CTD PMID:25270620 NCBI chr12:119,667,952...119,681,619
Ensembl chr12:119,667,864...119,681,624
JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 increases expression EXP diethyl maleate results in increased expression of PRKAG2 mRNA CTD PMID:33545341 NCBI chr 7:151,556,127...151,877,115
Ensembl chr 7:151,556,124...151,877,214
JBrowse link
G PRKCB protein kinase C beta affects expression EXP diethyl maleate affects the expression of PRKCB protein CTD PMID:31958493 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PRKCD protein kinase C delta multiple interactions ISO Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCD protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCD protein CTD PMID:11118818 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G PRKCE protein kinase C epsilon multiple interactions ISO Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCE protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCE protein CTD PMID:11118818 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990
JBrowse link
G PRSS8 serine protease 8 decreases expression ISO diethyl maleate results in decreased expression of PRSS8 mRNA CTD PMID:21161181 NCBI chr16:31,131,433...31,135,727
Ensembl chr16:31,131,433...31,135,727
JBrowse link
G PTGR1 prostaglandin reductase 1 increases expression ISO diethyl maleate results in increased expression of PTGR1 mRNA CTD PMID:25270620 NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893
JBrowse link
G PTPN14 protein tyrosine phosphatase non-receptor type 14 increases expression ISO diethyl maleate results in increased expression of PTPN14 mRNA CTD PMID:25270620 NCBI chr 1:214,348,700...214,551,602
Ensembl chr 1:214,348,700...214,552,449
JBrowse link
G PUS1 pseudouridine synthase 1 decreases expression ISO diethyl maleate results in decreased expression of PUS1 mRNA CTD PMID:25270620 NCBI chr12:131,929,276...131,945,896
Ensembl chr12:131,929,200...131,945,896
JBrowse link
G PXN paxillin increases expression EXP diethyl maleate results in increased expression of PXN mRNA CTD PMID:33545341 NCBI chr12:120,210,447...120,265,730
Ensembl chr12:120,210,439...120,265,771
JBrowse link
G RAB27A RAB27A, member RAS oncogene family decreases expression ISO diethyl maleate results in decreased expression of RAB27A mRNA CTD PMID:21161181 NCBI chr15:55,202,966...55,289,813
Ensembl chr15:55,202,966...55,319,113
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]]; diethyl maleate inhibits the reaction [IL1B protein affects the localization of RELA protein]; diethyl maleate inhibits the reaction [TNF protein affects the localization of RELA protein]; RELA protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]]; RELA protein inhibits the reaction [diethyl maleate results in increased expression of NFE2L2 protein]; RELA protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]; RELA protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein] CTD PMID:20116392 PMID:35724838 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RHO rhodopsin increases expression EXP diethyl maleate results in increased expression of RHO mRNA CTD PMID:33545341 NCBI chr 3:129,528,639...129,535,344
Ensembl chr 3:129,528,639...129,535,344
JBrowse link
G RNF114 ring finger protein 114 decreases expression ISO diethyl maleate results in decreased expression of RNF114 mRNA CTD PMID:25270620 NCBI chr20:49,936,397...49,953,885
Ensembl chr20:49,936,336...49,953,885
JBrowse link
G RNF14 ring finger protein 14 increases expression ISO diethyl maleate results in increased expression of RNF14 mRNA CTD PMID:25270620 NCBI chr 5:141,949,337...141,990,292
Ensembl chr 5:141,958,328...141,990,292
JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 increases expression ISO
EXP
diethyl maleate results in increased expression of RRM2 mRNA CTD PMID:21161181 PMID:33545341 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725
JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of RSAD2 mRNA CTD PMID:21161181 NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239
JBrowse link
G S100A9 S100 calcium binding protein A9 decreases expression ISO diethyl maleate results in decreased expression of S100A9 mRNA CTD PMID:21161181 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
JBrowse link
G SASH3 SAM and SH3 domain containing 3 decreases expression ISO diethyl maleate results in decreased expression of SASH3 mRNA CTD PMID:21161181 NCBI chr  X:129,779,949...129,795,201
Ensembl chr  X:129,779,949...129,795,201
JBrowse link
G SCARB1 scavenger receptor class B member 1 decreases expression EXP diethyl maleate results in decreased expression of SCARB1 mRNA CTD PMID:34480604 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SCD stearoyl-CoA desaturase decreases expression ISO diethyl maleate results in decreased expression of SCD1 mRNA CTD PMID:21161181 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
JBrowse link
G SDS serine dehydratase decreases expression ISO diethyl maleate results in decreased expression of SDS mRNA CTD PMID:21161181 NCBI chr12:113,392,445...113,403,887
Ensembl chr12:113,392,445...113,426,301
JBrowse link
G SELENOP selenoprotein P decreases expression EXP diethyl maleate results in decreased expression of SELENOP mRNA CTD PMID:30261343 NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392
JBrowse link
G SERPIND1 serpin family D member 1 decreases expression ISO diethyl maleate results in decreased expression of SERPIND1 mRNA CTD PMID:25270620 NCBI chr22:20,774,113...20,787,720
Ensembl chr22:20,774,113...20,787,720
JBrowse link
G SERTAD1 SERTA domain containing 1 increases expression EXP diethyl maleate results in increased expression of SERTAD1 mRNA CTD PMID:33545341 NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992
JBrowse link
G SEZ6 seizure related 6 homolog decreases expression ISO diethyl maleate results in decreased expression of SEZ6 mRNA CTD PMID:21161181 NCBI chr17:28,954,905...29,006,440
Ensembl chr17:28,954,901...29,006,440
JBrowse link
G SFXN1 sideroflexin 1 decreases expression ISO diethyl maleate results in decreased expression of SFXN1 mRNA CTD PMID:25270620 NCBI chr 5:175,478,560...175,529,742
Ensembl chr 5:175,477,062...175,529,742
JBrowse link
G SH3BP5 SH3 domain binding protein 5 increases expression
affects expression
EXP diethyl maleate results in increased expression of SH3BP5 mRNA
diethyl maleate affects the expression of SH3BP5 mRNA
CTD PMID:33545341 PMID:34480604 NCBI chr 3:15,254,353...15,341,380
Ensembl chr 3:15,254,353...15,341,368
JBrowse link
G SIX4 SIX homeobox 4 increases expression ISO diethyl maleate results in increased expression of SIX4 mRNA CTD PMID:25270620 NCBI chr14:60,709,539...60,724,351
Ensembl chr14:60,709,539...60,724,351
JBrowse link
G SLC16A6 solute carrier family 16 member 6 decreases expression ISO diethyl maleate results in decreased expression of SLC16A6 mRNA CTD PMID:25270620 NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267
JBrowse link
G SLC1A4 solute carrier family 1 member 4 increases expression ISO diethyl maleate results in increased expression of SLC1A4 mRNA CTD PMID:25270620 NCBI chr 2:64,988,479...65,023,865
Ensembl chr 2:64,988,477...65,023,865
JBrowse link
G SLC2A2 solute carrier family 2 member 2 decreases expression ISO diethyl maleate results in decreased expression of SLC2A2 mRNA CTD PMID:21161181 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
JBrowse link
G SLC2A5 solute carrier family 2 member 5 decreases expression ISO diethyl maleate results in decreased expression of SLC2A5 mRNA CTD PMID:21161181 NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478
JBrowse link
G SLC39A14 solute carrier family 39 member 14 decreases expression ISO diethyl maleate results in decreased expression of SLC39A14 mRNA CTD PMID:25270620 NCBI chr 8:22,367,278...22,434,129
Ensembl chr 8:22,367,278...22,434,129
JBrowse link
G SLC3A2 solute carrier family 3 member 2 increases expression EXP diethyl maleate results in increased expression of SLC3A2 mRNA CTD PMID:33545341 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880
JBrowse link
G SLC40A1 solute carrier family 40 member 1 multiple interactions EXP diethyl maleate inhibits the reaction [Lipopolysaccharides results in decreased expression of SLC40A1 mRNA] CTD PMID:21303654 NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758
JBrowse link
G SLC44A4 solute carrier family 44 member 4 decreases expression ISO diethyl maleate results in decreased expression of SLC44A4 mRNA CTD PMID:21161181 NCBI chr 6:31,863,192...31,878,997
Ensembl chr 6:31,863,192...31,879,046
JBrowse link
G SLC7A11 solute carrier family 7 member 11 multiple interactions
increases expression
ISO
EXP
NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA] CTD PMID:12235164 PMID:33545341 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
G SLCO2A1 solute carrier organic anion transporter family member 2A1 decreases expression ISO diethyl maleate results in decreased expression of SLCO2A1 mRNA CTD PMID:21161181 NCBI chr 3:133,932,701...134,029,925
Ensembl chr 3:133,932,701...134,052,184
JBrowse link
G SMC4 structural maintenance of chromosomes 4 increases expression ISO diethyl maleate results in increased expression of SMC4 mRNA CTD PMID:21161181 NCBI chr 3:160,399,650...160,434,953
Ensembl chr 3:160,399,274...160,434,954
JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 increases expression
multiple interactions
increases activity
EXP diethyl maleate results in increased expression of SMPD1 mRNA
Dactinomycin inhibits the reaction [diethyl maleate results in increased expression of SMPD1 mRNA]; diethyl maleate promotes the reaction [NFE2L2 protein binds to SMPD1 promoter]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SMPD1 mRNA]
diethyl maleate results in increased activity of SMPD1 protein
CTD PMID:25762726 NCBI chr11:6,390,474...6,394,996
Ensembl chr11:6,390,440...6,394,998
JBrowse link
G SMTN smoothelin increases expression ISO diethyl maleate results in increased expression of SMTN mRNA CTD PMID:21161181 NCBI chr22:31,064,118...31,104,624
Ensembl chr22:31,064,105...31,104,757
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 decreases expression ISO diethyl maleate results in decreased expression of SOCS3 mRNA CTD PMID:25270620 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SORL1 sortilin related receptor 1 decreases expression ISO diethyl maleate results in decreased expression of SORL1 mRNA CTD PMID:21161181 NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763
JBrowse link
G SOX9 SRY-box transcription factor 9 increases expression ISO diethyl maleate results in increased expression of SOX9 mRNA CTD PMID:21161181 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
JBrowse link
G SP5 Sp5 transcription factor decreases expression ISO diethyl maleate results in decreased expression of SP5 mRNA CTD PMID:25270620 NCBI chr 2:170,715,337...170,718,078
Ensembl chr 2:170,715,337...170,718,078
JBrowse link
G SPC25 SPC25 component of NDC80 kinetochore complex increases expression ISO diethyl maleate results in increased expression of SPC25 mRNA CTD PMID:21161181 NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371
JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 increases expression ISO diethyl maleate results in increased expression of SPTA1 mRNA CTD PMID:25270620 NCBI chr 1:158,610,704...158,686,715
Ensembl chr 1:158,610,704...158,686,715
JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 increases cleavage EXP diethyl maleate results in increased cleavage of SPTAN1 protein CTD PMID:21105742 NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662
JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 increases expression ISO diethyl maleate results in increased expression of SPTBN4 mRNA CTD PMID:25270620 NCBI chr19:40,467,001...40,576,464
Ensembl chr19:40,466,241...40,576,464
JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 increases expression EXP diethyl maleate results in increased expression of SPTLC1 mRNA CTD PMID:33545341 NCBI chr 9:92,031,147...92,115,413
Ensembl chr 9:92,000,087...92,115,413
JBrowse link
G SQSTM1 sequestosome 1 increases expression ISO
EXP
diethyl maleate results in increased expression of SQSTM1 mRNA CTD PMID:25270620 PMID:33545341 PMID:34480604 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 decreases expression ISO diethyl maleate results in decreased expression of SREBF1 mRNA CTD PMID:21161181 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G SRXN1 sulfiredoxin 1 multiple interactions
decreases expression
increases expression
ISO
EXP
[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]
diethyl maleate results in decreased expression of SRXN1 mRNA
diethyl maleate results in increased expression of SRXN1 mRNA; diethyl maleate results in increased expression of SRXN1 protein
[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; NFE2L2 protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]; RELA protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; RELA protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]; TNFAIP3 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
CTD PMID:22003191 PMID:25270620 PMID:27358234 PMID:27982581 PMID:33545341 More... NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
JBrowse link
G STAT1 signal transducer and activator of transcription 1 decreases expression ISO diethyl maleate results in decreased expression of STAT1 mRNA CTD PMID:21161181 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
G STEAP4 STEAP4 metalloreductase decreases expression ISO diethyl maleate results in decreased expression of STEAP4 mRNA CTD PMID:25270620 NCBI chr 7:88,270,892...88,306,894
Ensembl chr 7:88,270,892...88,306,894
JBrowse link
G SULF2 sulfatase 2 decreases expression ISO diethyl maleate results in decreased expression of SULF2 mRNA CTD PMID:21161181 NCBI chr20:47,657,406...47,786,627
Ensembl chr20:47,656,197...47,786,616
JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 decreases expression ISO diethyl maleate results in decreased expression of SULT1A1 protein CTD PMID:21161181 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044
JBrowse link
G TAGLN transgelin decreases expression ISO diethyl maleate results in decreased expression of TAGLN mRNA CTD PMID:21161181 NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464
JBrowse link
G TATDN2 TatD DNase domain containing 2 increases expression EXP diethyl maleate results in increased expression of TATDN2 mRNA CTD PMID:33545341 NCBI chr 3:10,248,459...10,281,218
Ensembl chr 3:10,248,023...10,281,218
JBrowse link
G TBCEL tubulin folding cofactor E like increases expression ISO diethyl maleate results in increased expression of TBCEL mRNA CTD PMID:25270620 NCBI chr11:121,024,102...121,090,776
Ensembl chr11:121,024,072...121,090,776
JBrowse link
G TENT4A terminal nucleotidyltransferase 4A increases expression EXP diethyl maleate results in increased expression of TENT4A mRNA CTD PMID:33545341 NCBI chr 5:6,713,432...6,757,044
Ensembl chr 5:6,713,432...6,757,044
JBrowse link
G TENT5A terminal nucleotidyltransferase 5A decreases expression ISO diethyl maleate results in decreased expression of TENT5A mRNA CTD PMID:21161181 NCBI chr 6:81,745,730...81,752,681
Ensembl chr 6:81,491,439...81,752,774
JBrowse link
G TESMIN testis expressed metallothionein like protein affects localization ISO diethyl maleate affects the localization of TESMIN protein CTD PMID:12606435 NCBI chr11:68,704,796...68,751,520
Ensembl chr11:68,707,440...68,751,520
JBrowse link
G TF transferrin decreases expression ISO diethyl maleate results in decreased expression of TF protein CTD PMID:21161181 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
JBrowse link
G TFEB transcription factor EB decreases expression ISO diethyl maleate results in decreased expression of TFEB mRNA CTD PMID:25270620 NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259
JBrowse link
G TGM2 transglutaminase 2 increases expression ISO diethyl maleate results in increased expression of TGM2 mRNA CTD PMID:21161181 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578
JBrowse link
G THBS1 thrombospondin 1 increases expression ISO diethyl maleate results in increased expression of THBS1 mRNA CTD PMID:21161181 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
JBrowse link
G THRSP thyroid hormone responsive decreases expression ISO diethyl maleate results in decreased expression of THRSP mRNA CTD PMID:21161181 NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351
JBrowse link
G TM4SF1 transmembrane 4 L six family member 1 increases expression ISO diethyl maleate results in increased expression of TM4SF1 mRNA CTD PMID:21161181 NCBI chr 3:149,369,022...149,377,649
Ensembl chr 3:149,369,022...149,377,692
JBrowse link
G TMEM209 transmembrane protein 209 increases expression ISO diethyl maleate results in increased expression of TMEM209 mRNA CTD PMID:25270620 NCBI chr 7:130,164,713...130,205,406
Ensembl chr 7:130,164,713...130,207,770
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO
[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein; [diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein; diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]]; diethyl maleate inhibits the reaction [TNF protein affects the localization of NFKBIA protein]; diethyl maleate inhibits the reaction [TNF protein affects the localization of RELA protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; NFE2L2 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]]; RELA protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]; TNFAIP3 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; TNFAIP3 protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]
diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate]
diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]
CTD PMID:7476933 PMID:7532384 PMID:12774022 PMID:20116392 PMID:31958493 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 multiple interactions EXP diethyl maleate inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]]; TNFAIP3 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; TNFAIP3 protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein] CTD PMID:35724838 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 decreases expression ISO diethyl maleate results in decreased expression of TNFRSF14 mRNA CTD PMID:21161181 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382
JBrowse link
G TP53 tumor protein p53 multiple interactions ISO
EXP
TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]
TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
CTD PMID:22003191 PMID:27982581 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TPM2 tropomyosin 2 decreases expression ISO diethyl maleate results in decreased expression of TPM2 mRNA CTD PMID:21161181 NCBI chr 9:35,681,993...35,690,056
Ensembl chr 9:35,681,992...35,690,056
JBrowse link
G TRAP1 TNF receptor associated protein 1 multiple interactions
decreases response to substance
EXP diethyl maleate inhibits the reaction [Cisplatin results in decreased expression of TRAP1 protein]
TRAP1 protein results in decreased susceptibility to diethyl maleate
CTD PMID:17853063 NCBI chr16:3,658,037...3,717,524
Ensembl chr16:3,651,639...3,717,553
JBrowse link
G TRDMT1 tRNA aspartic acid methyltransferase 1 decreases expression ISO diethyl maleate results in decreased expression of TRDMT1 mRNA CTD PMID:25270620 NCBI chr10:17,137,336...17,201,672
Ensembl chr10:17,137,336...17,202,054
JBrowse link
G TRIB1 tribbles pseudokinase 1 increases expression EXP diethyl maleate results in increased expression of TRIB1 mRNA CTD PMID:33545341 NCBI chr 8:125,430,358...125,438,403
Ensembl chr 8:125,430,358...125,438,403
JBrowse link
G TRIB3 tribbles pseudokinase 3 increases expression EXP diethyl maleate results in increased expression of TRIB3 mRNA CTD PMID:33545341 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
JBrowse link
G TRIM6 tripartite motif containing 6 decreases expression ISO diethyl maleate results in decreased expression of TRIM6 mRNA CTD PMID:21161181 NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958
JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 increases expression ISO diethyl maleate results in increased expression of TRIP13 mRNA CTD PMID:21161181 NCBI chr 5:892,884...919,348
Ensembl chr 5:892,884...919,357
JBrowse link
G TSC22D1 TSC22 domain family member 1 decreases expression ISO diethyl maleate results in decreased expression of TSC22D1 mRNA CTD PMID:21161181 NCBI chr13:44,432,143...44,577,344
Ensembl chr13:44,432,143...44,577,147
JBrowse link
G TSPAN8 tetraspanin 8 decreases expression ISO diethyl maleate results in decreased expression of TSPAN8 mRNA CTD PMID:21161181 NCBI chr12:71,125,096...71,157,999
Ensembl chr12:71,125,085...71,441,898
JBrowse link
G TSTD1 thiosulfate sulfurtransferase like domain containing 1 decreases expression ISO diethyl maleate results in decreased expression of TSTD1 mRNA CTD PMID:25270620 NCBI chr 1:161,037,631...161,038,964
Ensembl chr 1:161,037,631...161,038,977
JBrowse link
G TXN thioredoxin decreases activity EXP diethyl maleate results in decreased activity of TXN protein CTD PMID:15388247 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G TXNIP thioredoxin interacting protein increases expression ISO diethyl maleate results in increased expression of TXNIP mRNA CTD PMID:21161181 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP diethyl maleate results in increased expression of TXNRD1 mRNA CTD PMID:15521073 PMID:33545341 PMID:34480604 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G UBD ubiquitin D decreases expression ISO diethyl maleate results in decreased expression of UBD mRNA CTD PMID:21161181 NCBI chr 6:29,555,515...29,559,732
Ensembl chr 6:29,555,515...29,559,732
JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 increases expression ISO diethyl maleate results in increased expression of UHRF1 mRNA CTD PMID:21161181 NCBI chr19:4,903,080...4,962,154
Ensembl chr19:4,903,080...4,962,154
JBrowse link
G USP18 ubiquitin specific peptidase 18 decreases expression ISO diethyl maleate results in decreased expression of USP18 mRNA CTD PMID:21161181 NCBI chr22:18,150,170...18,177,397
Ensembl chr22:18,150,118...18,177,397
JBrowse link
G USP2 ubiquitin specific peptidase 2 decreases expression ISO diethyl maleate results in decreased expression of USP2 mRNA CTD PMID:21161181 NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711
JBrowse link
G VEGFA vascular endothelial growth factor A increases expression EXP diethyl maleate results in increased expression of VEGFA mRNA CTD PMID:33545341 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G WDR31 WD repeat domain 31 decreases expression ISO diethyl maleate results in decreased expression of WDR31 mRNA CTD PMID:25270620 NCBI chr 9:113,313,222...113,340,275
Ensembl chr 9:113,313,222...113,340,298
JBrowse link
G WDR6 WD repeat domain 6 decreases expression ISO diethyl maleate results in decreased expression of WDR6 mRNA CTD PMID:21161181 NCBI chr 3:49,007,391...49,015,951
Ensembl chr 3:49,007,062...49,015,953
JBrowse link
G YPEL5 yippee like 5 increases expression ISO diethyl maleate results in increased expression of YPEL5 mRNA CTD PMID:25270620 NCBI chr 2:30,147,007...30,160,533
Ensembl chr 2:30,146,941...30,160,533
JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A increases expression EXP diethyl maleate results in increased expression of ZFAND2A mRNA CTD PMID:33545341 PMID:34480604 NCBI chr 7:1,148,850...1,160,196
Ensembl chr 7:1,152,071...1,160,759
JBrowse link
G ZFP36 ZFP36 ring finger protein increases expression EXP diethyl maleate results in increased expression of ZFP36 protein CTD PMID:21969073 NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,412
JBrowse link
G ZFP37 ZFP37 zinc finger protein decreases expression ISO diethyl maleate results in decreased expression of ZFP37 mRNA CTD PMID:21161181 NCBI chr 9:113,038,377...113,056,724
Ensembl chr 9:113,038,377...113,056,759
JBrowse link
G ZNF367 zinc finger protein 367 increases expression ISO diethyl maleate results in increased expression of ZNF367 mRNA CTD PMID:21161181 NCBI chr 9:96,385,941...96,418,370
Ensembl chr 9:96,385,941...96,418,370
JBrowse link
G ZNRD2 zinc ribbon domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of ZNRD2 mRNA CTD PMID:25270620 NCBI chr11:65,570,477...65,571,888
Ensembl chr11:65,570,460...65,573,942
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      biological role 25935
        glutathione depleting agent 399
          diethyl maleate 399
paths to the root