CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: glutathione depleting agent
Accession: CHEBI:68509
browse the term
Definition: A compound which causes a reduction in the levels of glutathione in cells.
Synonyms: related_synonym: glutathione depleting agents; glutathione depletion agent; glutathione depletion agents; glutathione depletor; glutathione depletors
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Abcc2
ATP binding cassette subfamily C member 2
increases expression
ISO
diethyl maleate results in increased expression of ABCC2 mRNA
CTD
PMID:25270620
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
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Abhd4
abhydrolase domain containing 4, N-acyl phospholipase B
increases expression
ISO
diethyl maleate results in increased expression of ABHD4 mRNA
CTD
PMID:25270620
NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
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Acaca
acetyl-CoA carboxylase alpha
decreases expression
ISO
diethyl maleate results in decreased expression of ACACA mRNA
CTD
PMID:25270620
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
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Acox1
acyl-CoA oxidase 1
multiple interactions
EXP
diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]
CTD
PMID:17134953
NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232
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Acy3
aminoacylase 3
decreases expression
EXP
diethyl maleate results in decreased expression of ACY3 mRNA
CTD
PMID:21161181
NCBI chr 1:201,279,751...201,285,803
Ensembl chr 1:201,279,851...201,283,175
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Adm
adrenomedullin
increases expression
ISO
diethyl maleate results in increased expression of ADM mRNA
CTD
PMID:33545341
NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:164,745,466...164,747,654
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Adora3
adenosine A3 receptor
decreases expression
EXP
diethyl maleate results in decreased expression of ADORA3 mRNA
CTD
PMID:21161181
NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
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Aen
apoptosis enhancing nuclease
increases expression
ISO
diethyl maleate results in increased expression of AEN mRNA
CTD
PMID:33545341
NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
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Afp
alpha-fetoprotein
increases expression
ISO
diethyl maleate results in increased expression of AFP mRNA
CTD
PMID:25270620
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,573,412...17,591,480
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Ahcyl1
adenosylhomocysteinase-like 1
increases expression
ISO
diethyl maleate results in increased expression of AHCYL1 mRNA
CTD
PMID:25270620
NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815
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Akr1a1
aldo-keto reductase family 1 member A1
increases expression
EXP
diethyl maleate results in increased expression of AKR1A1 protein
CTD
PMID:21161181
NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:130,092,732...130,113,674
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Akr1b10
aldo-keto reductase family 1 member B10
increases expression
ISO
diethyl maleate results in increased expression of AKR1B10 mRNA
CTD
PMID:33545341
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:63,040,169...63,053,852
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Akr1c14
aldo-keto reductase family 1, member C14
decreases expression
EXP
diethyl maleate results in decreased expression of AKR1C14 protein
CTD
PMID:21161181
NCBI chr17:66,156,286...66,173,277
Ensembl chr17:66,156,288...66,173,277
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Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
diethyl maleate results in increased expression of AKR1C2 mRNA
CTD
PMID:20491607
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects reduction
ISO
diethyl maleate affects the reduction of ALDH1A1 protein
CTD
PMID:19843705
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961
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Aldh1b1
aldehyde dehydrogenase 1 family, member B1
decreases expression
EXP
diethyl maleate results in decreased expression of ALDH1B1 mRNA
CTD
PMID:21161181
NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:60,063,225...60,068,378
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Aldh2
aldehyde dehydrogenase 2 family member
decreases reduction decreases expression increases expression
ISO EXP
diethyl maleate results in decreased reduction of ALDH2 protein diethyl maleate results in decreased expression of ALDH2 protein diethyl maleate results in increased expression of ALDH2 protein
CTD
PMID:19843705 PMID:21161181
NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521
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Aldoa
aldolase, fructose-bisphosphate A
affects expression
ISO
diethyl maleate affects the expression of ALDOA mRNA
CTD
PMID:34480604
NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:181,402,275...181,406,182
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Aldob
aldolase, fructose-bisphosphate B
decreases expression
EXP
diethyl maleate results in decreased expression of ALDOB protein
CTD
PMID:21161181
NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:63,889,046...63,902,116
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Amigo2
adhesion molecule with Ig like domain 2
decreases expression
EXP
diethyl maleate results in decreased expression of AMIGO2 mRNA
CTD
PMID:21161181
NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
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Angptl2
angiopoietin-like 2
decreases expression
EXP
diethyl maleate results in decreased expression of ANGPTL2 mRNA
CTD
PMID:21161181
NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
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Angptl4
angiopoietin-like 4
increases expression
ISO
diethyl maleate results in increased expression of ANGPTL4 mRNA
CTD
PMID:33545341
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Ankrd46
ankyrin repeat domain 46
decreases expression
EXP
diethyl maleate results in decreased expression of ANKRD46 mRNA
CTD
PMID:21161181
NCBI chr 7:67,647,202...67,668,180
Ensembl chr 7:67,647,204...67,668,132
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Anln
anillin, actin binding protein
increases expression
EXP
diethyl maleate results in increased expression of ANLN mRNA
CTD
PMID:21161181
NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
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Anxa1
annexin A1
affects expression
ISO
diethyl maleate affects the expression of ANXA1 mRNA
CTD
PMID:34480604
NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343
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Anxa3
annexin A3
decreases expression
EXP
diethyl maleate results in decreased expression of ANXA3 mRNA
CTD
PMID:21161181
NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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Ap3m2
adaptor related protein complex 3 subunit mu 2
decreases expression
EXP
diethyl maleate results in decreased expression of AP3M2 mRNA
CTD
PMID:21161181
NCBI chr16:69,217,526...69,237,372
Ensembl chr16:69,217,633...69,235,431
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Apaf1
apoptotic peptidase activating factor 1
increases expression
ISO
diethyl maleate results in increased expression of APAF1 mRNA
CTD
PMID:11875189
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540
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Aplp1
amyloid beta precursor like protein 1
decreases expression
ISO
diethyl maleate results in decreased expression of APLP1 mRNA
CTD
PMID:25270620
NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155
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Apol9a
apolipoprotein L9a
decreases expression
EXP
diethyl maleate results in decreased expression of APOL9A mRNA
CTD
PMID:21161181
NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649
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Arhgap9
Rho GTPase activating protein 9
increases expression
ISO
diethyl maleate results in increased expression of ARHGAP9 mRNA
CTD
PMID:33545341
NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
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Arrdc2
arrestin domain containing 2
decreases expression
EXP
diethyl maleate results in decreased expression of ARRDC2 mRNA
CTD
PMID:21161181
NCBI chr16:18,635,883...18,640,019
Ensembl chr16:18,601,897...18,606,029
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Arrdc4
arrestin domain containing 4
decreases expression
ISO
diethyl maleate results in decreased expression of ARRDC4 mRNA
CTD
PMID:25270620
NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
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Asf1b
anti-silencing function 1B histone chaperone
increases expression
EXP
diethyl maleate results in increased expression of ASF1B mRNA
CTD
PMID:21161181
NCBI chr19:41,085,786...41,100,352
Ensembl chr19:24,181,028...24,195,549
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Asxl1
ASXL transcriptional regulator 1
decreases expression
ISO
diethyl maleate results in decreased expression of ASXL1 mRNA
CTD
PMID:25270620
NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538
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Atm
ATM serine/threonine kinase
increases expression
ISO
diethyl maleate results in increased expression of ATM mRNA
CTD
PMID:11875189
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437
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Atp5f1b
ATP synthase F1 subunit beta
increases expression
EXP
diethyl maleate results in increased expression of ATP5F1B protein
CTD
PMID:21161181
NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:515,460...567,273
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Aurka
aurora kinase A
increases expression decreases expression
EXP ISO
diethyl maleate results in increased expression of AURKA mRNA diethyl maleate results in decreased expression of AURKA mRNA
CTD
PMID:21161181 PMID:25270620
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:161,128,313...161,144,390
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Bbc3
Bcl-2 binding component 3
increases expression
ISO
diethyl maleate results in increased expression of BBC3 mRNA
CTD
PMID:33545341
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509
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Bcl2
BCL2, apoptosis regulator
multiple interactions increases expression
ISO
[diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of BCL2 mRNA diethyl maleate results in increased expression of BCL2 mRNA
CTD
PMID:22564015 PMID:33545341
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2a1
BCL2-related protein A1
decreases expression
EXP
diethyl maleate results in decreased expression of BCL2A1 mRNA
CTD
PMID:21161181
NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:89,716,914...89,724,998
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Bcl3
BCL3, transcription coactivator
decreases expression
ISO
diethyl maleate results in decreased expression of BCL3 mRNA
CTD
PMID:25270620
NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:79,471,369...79,485,607
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Bcl6b
BCL6B, transcription repressor
decreases expression
EXP
diethyl maleate results in decreased expression of BCL6B mRNA
CTD
PMID:21161181
NCBI chr10:55,439,566...55,444,631
Ensembl chr10:54,940,909...54,945,974
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Bhlhe41
basic helix-loop-helix family, member e41
decreases expression
EXP
diethyl maleate results in decreased expression of BHLHE41 mRNA
CTD
PMID:21161181
NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468
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Bhmt
betaine-homocysteine S-methyltransferase
decreases expression
EXP
diethyl maleate results in decreased expression of BHMT mRNA
CTD
PMID:21161181
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Birc3
baculoviral IAP repeat-containing 3
multiple interactions
ISO
diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA]
CTD
PMID:12774022
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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Blvrb
biliverdin reductase B
increases expression
ISO
diethyl maleate results in increased expression of BLVRB mRNA
CTD
PMID:25270620 PMID:34626751
NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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Bmf
Bcl2 modifying factor
decreases expression
EXP
diethyl maleate results in decreased expression of BMF mRNA
CTD
PMID:21161181
NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:105,499,538...105,520,145
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Brip1
BRCA1 interacting DNA helicase 1
increases expression
EXP
diethyl maleate results in increased expression of BRIP1 mRNA
CTD
PMID:21161181
NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
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Btbd2
BTB domain containing 2
decreases expression
EXP
diethyl maleate results in decreased expression of BTBD2 mRNA
CTD
PMID:21161181
NCBI chr 7:9,058,609...9,075,341
Ensembl chr 7:9,060,788...9,075,344
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Btg2
BTG anti-proliferation factor 2
increases expression multiple interactions decreases expression
ISO
diethyl maleate results in increased expression of BTG2 mRNA NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA] diethyl maleate results in decreased expression of BTG2 mRNA
CTD
PMID:22003191 PMID:25270620 PMID:34626751
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:45,531,925...45,535,628
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C6
complement C6
decreases expression
EXP
diethyl maleate results in decreased expression of C6 mRNA
CTD
PMID:21161181
NCBI chr 2:55,573,596...55,648,857
Ensembl chr 2:53,851,985...53,921,275
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Casp2
caspase 2
increases expression
ISO
diethyl maleate results in increased expression of CASP2 mRNA
CTD
PMID:11875189
NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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Casp3
caspase 3
increases expression increases cleavage
ISO
diethyl maleate results in increased expression of CASP3 mRNA diethyl maleate results in increased cleavage of CASP3 protein
CTD
PMID:11875189 PMID:21105742
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
increases expression
ISO
diethyl maleate results in increased expression of CASP9 mRNA
CTD
PMID:11875189
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
decreases expression
EXP
diethyl maleate results in decreased expression of CAT protein
CTD
PMID:21161181
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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Cbr1
carbonyl reductase 1
increases expression
ISO
diethyl maleate results in increased expression of CBR1 mRNA
CTD
PMID:25270620
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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Cbr3
carbonyl reductase 3
increases expression multiple interactions
ISO
diethyl maleate results in increased expression of CBR3 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diethyl maleate results in increased expression of CBR3 mRNA]
CTD
PMID:20806931 PMID:25270620
NCBI chr11:46,478,295...46,486,555
Ensembl chr11:33,008,615...33,016,875
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Cbx4
chromobox 4
increases expression
ISO
diethyl maleate results in increased expression of CBX4 mRNA
CTD
PMID:33545341
NCBI chr10:104,835,685...104,841,727
Ensembl chr10:104,336,876...104,356,706
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Ccdc50
coiled-coil domain containing 50
decreases expression
ISO
diethyl maleate results in decreased expression of CCDC50 mRNA
CTD
PMID:25270620
NCBI chr11:73,332,798...73,395,333
Ensembl chr11:73,334,248...73,395,150
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Ccna1
cyclin A1
decreases expression
ISO
diethyl maleate results in decreased expression of CCNA1 mRNA
CTD
PMID:11875189
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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Ccna2
cyclin A2
increases expression
EXP
diethyl maleate results in increased expression of CCNA2 mRNA
CTD
PMID:21161181
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577
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Ccnd1
cyclin D1
decreases expression increases expression
ISO EXP
diethyl maleate results in decreased expression of CCND1 mRNA diethyl maleate results in increased expression of CCND1 mRNA
CTD
PMID:11875189 PMID:21161181 PMID:25270620
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
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Ccne2
cyclin E2
increases expression
EXP
diethyl maleate results in increased expression of CCNE2 mRNA
CTD
PMID:21161181
NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:24,284,922...24,297,632
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Ccnk
cyclin K
decreases expression
ISO
diethyl maleate results in decreased expression of CCNK mRNA
CTD
PMID:11875189
NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
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Cd80
Cd80 molecule
multiple interactions increases expression
ISO
[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein diethyl maleate results in increased expression of CD80 protein
CTD
PMID:31958493
NCBI chr11:75,760,073...75,798,978
Ensembl chr11:62,254,624...62,292,030
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Cd86
CD86 molecule
multiple interactions increases expression
ISO
[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; bisindolylmaleimide I inhibits the reaction [diethyl maleate results in increased expression of CD86 protein]
CTD
PMID:24136171 PMID:31958493
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818
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Cdc25a
cell division cycle 25A
increases expression
EXP
diethyl maleate results in increased expression of CDC25A mRNA
CTD
PMID:21161181
NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:109,864,478...109,882,701
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Cdca2
cell division cycle associated 2
increases expression
EXP
diethyl maleate results in increased expression of CDCA2 mRNA
CTD
PMID:21161181
NCBI chr15:46,071,360...46,117,524
Ensembl chr15:41,895,901...41,941,611
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Cdca3
cell division cycle associated 3
increases expression
EXP
diethyl maleate results in increased expression of CDCA3 mRNA
CTD
PMID:21161181
NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
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Cdca8
cell division cycle associated 8
increases expression
EXP
diethyl maleate results in increased expression of CDCA8 mRNA
CTD
PMID:21161181
NCBI chr 5:142,461,082...142,483,336
Ensembl chr 5:137,176,417...137,198,629
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Cdh11
cadherin 11
decreases expression
EXP
diethyl maleate results in decreased expression of CDH11 mRNA
CTD
PMID:21161181
NCBI chr19:2,152,961...2,312,140
Ensembl chr19:2,148,458...2,304,272
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression multiple interactions
ISO
diethyl maleate results in increased expression of CDKN1A mRNA; diethyl maleate results in increased expression of CDKN1A protein TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]
CTD
PMID:11875189 PMID:27982581
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
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Cds2
CDP-diacylglycerol synthase 2
increases expression
ISO
diethyl maleate results in increased expression of CDS2 mRNA
CTD
PMID:25270620
NCBI chr 3:139,967,870...140,006,459
Ensembl chr 3:119,515,000...119,553,541
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Ces1d
carboxylesterase 1D
decreases expression increases reduction
EXP ISO
diethyl maleate results in decreased expression of CES1D protein diethyl maleate results in increased reduction of CES1D protein
CTD
PMID:19843705 PMID:21161181
NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035
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Cflar
CASP8 and FADD-like apoptosis regulator
decreases expression
EXP
diethyl maleate results in decreased expression of CFLAR mRNA
CTD
PMID:21161181
NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:60,185,452...60,237,034
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Chrna4
cholinergic receptor nicotinic alpha 4 subunit
increases expression
ISO
diethyl maleate results in increased expression of CHRNA4 mRNA
CTD
PMID:33545341
NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
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Cidec
cell death-inducing DFFA-like effector c
decreases expression
EXP
diethyl maleate results in decreased expression of CIDEC mRNA
CTD
PMID:21161181
NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:146,569,289...146,582,173
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Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
decreases expression
EXP
diethyl maleate results in decreased expression of CITED2 mRNA
CTD
PMID:21161181
NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
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Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
decreases expression
EXP
diethyl maleate results in decreased expression of CITED4 mRNA
CTD
PMID:21161181
NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135
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Ckb
creatine kinase B
decreases reduction
ISO
diethyl maleate results in decreased reduction of CKB protein
CTD
PMID:19843705
NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:130,729,423...130,732,315
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Cks2
CDC28 protein kinase regulatory subunit 2
increases expression
ISO
diethyl maleate results in increased expression of CKS2 mRNA
CTD
PMID:33545341
NCBI chr17:13,570,611...13,575,770
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Clk1
CDC-like kinase 1
increases expression
ISO
diethyl maleate results in increased expression of CLK1 mRNA
CTD
PMID:33545341
NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
G
Cmpk2
cytidine/uridine monophosphate kinase 2
decreases expression
EXP
diethyl maleate results in decreased expression of CMPK2 mRNA
CTD
PMID:21161181
NCBI chr 6:48,802,150...48,813,652
Ensembl chr 6:43,073,796...43,085,183
G
Cntn1
contactin 1
increases expression
ISO
diethyl maleate results in increased expression of CNTN1 mRNA
CTD
PMID:33545341
NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541
G
Col1a1
collagen type I alpha 1 chain
decreases expression
EXP
diethyl maleate results in decreased expression of COL1A1 mRNA
CTD
PMID:21161181
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
G
Col3a1
collagen type III alpha 1 chain
decreases expression
ISO
diethyl maleate results in decreased expression of COL3A1 mRNA
CTD
PMID:25270620
NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:47,374,593...47,410,547
G
Commd3
COMM domain containing 3
increases expression
ISO
diethyl maleate results in increased expression of COMMD3 mRNA
CTD
PMID:25270620
NCBI chr17:81,327,444...81,331,191
Ensembl chr17:81,327,405...81,331,177
G
Comt
catechol-O-methyltransferase
decreases expression
EXP
diethyl maleate results in decreased expression of COMT mRNA
CTD
PMID:21161181
NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642
G
Cp
ceruloplasmin
decreases expression
ISO
diethyl maleate results in decreased expression of CP mRNA
CTD
PMID:25270620
NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075
G
Cpsf4l
cleavage and polyadenylation specific factor 4-like
increases expression
ISO
diethyl maleate results in increased expression of CPSF4L mRNA
CTD
PMID:33545341
NCBI chr10:98,741,816...98,756,069
Ensembl chr10:98,743,649...98,751,590
G
Crym
crystallin, mu
decreases expression
EXP
diethyl maleate results in decreased expression of CRYM mRNA
CTD
PMID:21161181
NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
G
Csrp1
cysteine and glycine-rich protein 1
decreases expression
EXP
diethyl maleate results in decreased expression of CSRP1 mRNA
CTD
PMID:21161181
NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
G
Csrp3
cysteine and glycine rich protein 3
decreases reduction
ISO
diethyl maleate results in decreased reduction of CSRP3 protein
CTD
PMID:19843705
NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
G
Cxcl10
C-X-C motif chemokine ligand 10
decreases expression
EXP
diethyl maleate results in decreased expression of CXCL10 mRNA
CTD
PMID:21161181
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl12
C-X-C motif chemokine ligand 12
decreases expression
EXP
diethyl maleate results in decreased expression of CXCL12 mRNA
CTD
PMID:21161181
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168
G
Cxcl9
C-X-C motif chemokine ligand 9
decreases expression
EXP
diethyl maleate results in decreased expression of CXCL9 mRNA
CTD
PMID:21161181
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
G
Cyb5a
cytochrome b5 type A
increases expression
ISO
diethyl maleate results in increased expression of CYB5A mRNA
CTD
PMID:25270620
NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535 Ensembl chr18:78,202,342...78,258,535
G
Cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
decreases expression
EXP
diethyl maleate results in decreased expression of CYP26B1 mRNA
CTD
PMID:21161181
NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:117,041,808...117,058,628
G
Dbp
D-box binding PAR bZIP transcription factor
decreases expression
EXP
diethyl maleate results in decreased expression of DBP mRNA
CTD
PMID:21161181
NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:96,175,440...96,180,745
G
Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
diethyl maleate results in increased expression of DDIT3 mRNA; diethyl maleate results in increased expression of DDIT3 protein
CTD
PMID:33545341 PMID:35724838
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201
G
Ddit4
DNA-damage-inducible transcript 4
increases expression
ISO
diethyl maleate results in increased expression of DDIT4 mRNA
CTD
PMID:33545341
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:27,891,998...27,894,105
G
Ddit4l
DNA-damage-inducible transcript 4-like
increases expression
ISO
diethyl maleate results in increased expression of DDIT4L mRNA
CTD
PMID:25270620
NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
G
Ddx60
DEXD/H-box helicase 60
decreases expression
EXP
diethyl maleate results in decreased expression of DDX60 mRNA
CTD
PMID:21161181
NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526
G
Dhx58
DEXH-box helicase 58
decreases expression
EXP
diethyl maleate results in decreased expression of DHX58 mRNA
CTD
PMID:21161181
NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
G
Dnajb1
DnaJ heat shock protein family (Hsp40) member B1
increases expression
ISO
diethyl maleate results in increased expression of DNAJB1 mRNA
CTD
PMID:33545341 PMID:34480604
NCBI chr19:41,427,453...41,431,141
Ensembl chr19:24,522,717...24,526,458
G
Dnajb4
DnaJ heat shock protein family (Hsp40) member B4
increases expression
ISO
diethyl maleate results in increased expression of DNAJB4 mRNA
CTD
PMID:33545341
NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
G
Dnmbp
dynamin binding protein
decreases expression
EXP
diethyl maleate results in decreased expression of DNMBP mRNA
CTD
PMID:21161181
NCBI chr 1:242,736,189...242,829,431
Ensembl chr 1:242,736,189...242,802,604
G
Dpysl2
dihydropyrimidinase-like 2
decreases reduction
ISO
diethyl maleate results in decreased reduction of DPYSL2 protein
CTD
PMID:19843705
NCBI chr15:45,181,041...45,287,065
Ensembl chr15:41,005,551...41,111,829
G
Dtx3l
deltex E3 ubiquitin ligase 3L
decreases expression
EXP
diethyl maleate results in decreased expression of DTX3L mRNA
CTD
PMID:21161181
NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538
G
Dus3l
dihydrouridine synthase 3-like
decreases expression
ISO
diethyl maleate results in decreased expression of DUS3L mRNA
CTD
PMID:25270620
NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655
G
Dusp6
dual specificity phosphatase 6
increases expression
ISO
diethyl maleate results in increased expression of DUSP6 mRNA
CTD
PMID:33545341
NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:34,092,943...34,097,185
G
Eef2k
eukaryotic elongation factor-2 kinase
decreases expression
EXP
diethyl maleate results in decreased expression of EEF2K mRNA
CTD
PMID:21161181
NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164
G
Egln3
egl-9 family hypoxia-inducible factor 3
increases expression
ISO
diethyl maleate results in increased expression of EGLN3 mRNA
CTD
PMID:34480604
NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:71,650,297...71,675,766
G
Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
decreases expression
EXP
diethyl maleate results in decreased expression of EIF2AK2 mRNA
CTD
PMID:21161181
NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
G
Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
increases expression
ISO
diethyl maleate results in increased expression of ENTPD5 mRNA
CTD
PMID:25270620
NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530
G
Eras
ES cell expressed Ras
decreases expression
ISO
diethyl maleate results in decreased expression of ERAS mRNA
CTD
PMID:25270620
NCBI chr X:17,245,915...17,250,301
Ensembl chr X:14,573,987...14,578,374
G
Ercc6l
ERCC excision repair 6 like, spindle assembly checkpoint helicase
increases expression
EXP
diethyl maleate results in increased expression of ERCC6L mRNA
CTD
PMID:21161181
NCBI chr X:67,245,414...67,261,222
Ensembl chr X:67,245,414...67,280,756
G
Exo1
exonuclease 1
increases expression
EXP
diethyl maleate results in increased expression of EXO1 mRNA
CTD
PMID:21161181
NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
G
Fabp1
fatty acid binding protein 1
increases expression
EXP
diethyl maleate results in increased expression of FABP1 protein
CTD
PMID:21161181
NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788
G
Fabp7
fatty acid binding protein 7
decreases expression
EXP
diethyl maleate results in decreased expression of FABP7 mRNA
CTD
PMID:21161181
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
G
Fah
fumarylacetoacetate hydrolase
affects expression
ISO
diethyl maleate affects the expression of FAH mRNA
CTD
PMID:34480604
NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:138,548,834...138,571,505
G
Fam83d
family with sequence similarity 83, member D
increases expression
ISO
diethyl maleate results in increased expression of FAM83D mRNA
CTD
PMID:33545341
NCBI chr 3:167,841,748...167,861,062
Ensembl chr 3:147,421,908...147,441,192
G
Fasn
fatty acid synthase
decreases expression
EXP
diethyl maleate results in decreased expression of FASN mRNA
CTD
PMID:21161181
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
G
Fbn1
fibrillin 1
decreases expression
EXP
diethyl maleate results in decreased expression of FBN1 mRNA
CTD
PMID:21161181
NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:112,554,925...112,750,889
G
Fbp1
fructose-bisphosphatase 1
decreases expression
EXP
diethyl maleate results in decreased expression of FBP1 protein
CTD
PMID:21161181
NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,208,031...2,230,071
G
Fgf17
fibroblast growth factor 17
decreases expression
ISO
diethyl maleate results in decreased expression of FGF17 mRNA
CTD
PMID:25270620
NCBI chr15:52,118,141...52,132,083
Ensembl chr15:45,711,998...45,717,063
G
Fgg
fibrinogen gamma chain
decreases expression
ISO
diethyl maleate results in decreased expression of FGG mRNA
CTD
PMID:25270620
NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322
G
Fgr
FGR proto-oncogene, Src family tyrosine kinase
decreases expression
EXP
diethyl maleate results in decreased expression of FGR mRNA
CTD
PMID:21161181
NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
G
Fndc3b
fibronectin type III domain containing 3B
decreases expression
ISO
diethyl maleate results in decreased expression of FNDC3B mRNA
CTD
PMID:25270620
NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
diethyl maleate results in increased expression of FOS mRNA
CTD
PMID:10915739 PMID:33545341
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036
G
Foxo1
forkhead box O1
multiple interactions
ISO
diethyl maleate inhibits the reaction [INS protein affects the localization of and results in increased phosphorylation of FOXO1 protein]
CTD
PMID:30261343
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790
G
Foxo3
forkhead box O3
increases expression
ISO
diethyl maleate results in increased expression of FOXO3 mRNA
CTD
PMID:33545341
NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561
G
Fstl3
follistatin like 3
increases expression
ISO
diethyl maleate results in increased expression of FSTL3 mRNA
CTD
PMID:33545341
NCBI chr 7:10,574,195...10,579,844
Ensembl chr 7:9,923,576...9,939,639
G
G6pc1
glucose-6-phosphatase catalytic subunit 1
decreases expression
ISO
diethyl maleate results in decreased expression of G6PC1 mRNA
CTD
PMID:25270620 PMID:30261343
NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,257,668...86,333,804
G
G6pd
glucose-6-phosphate dehydrogenase
increases activity increases expression
EXP ISO
diethyl maleate results in increased activity of G6PD protein diethyl maleate results in increased expression of G6PD mRNA
CTD
PMID:3099627 PMID:30261343 PMID:33545341
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801
G
Gab1
GRB2-associated binding protein 1
decreases expression
ISO
diethyl maleate results in decreased expression of GAB1 mRNA
CTD
PMID:25270620
NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
diethyl maleate results in increased expression of GADD45A mRNA
CTD
PMID:33545341 PMID:34480604
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115
G
Gadd45g
growth arrest and DNA-damage-inducible, gamma
increases expression
ISO
diethyl maleate results in increased expression of GADD45G mRNA
CTD
PMID:33545341
NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,376,839...13,378,610
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
increases reduction
ISO
diethyl maleate results in increased reduction of GAPDH protein
CTD
PMID:19843705
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235
G
Gba2
glucosylceramidase beta 2
decreases expression
ISO
diethyl maleate results in decreased expression of GBA2 mRNA
CTD
PMID:25270620
NCBI chr 5:62,618,176...62,630,160
Ensembl chr 5:57,822,389...57,834,072
G
Gbp2
guanylate binding protein 2
decreases expression
EXP
diethyl maleate results in decreased expression of GBP2 mRNA
CTD
PMID:21161181
NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases activity increases expression
ISO EXP
diethyl maleate results in increased activity of GCLC protein diethyl maleate results in increased expression of GCLC mRNA; diethyl maleate results in increased expression of GCLC protein
CTD
PMID:10915739 PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 PMID:33545341 PMID:34021431 PMID:34480604 More...
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
EXP ISO
diethyl maleate results in increased expression of GCLM mRNA; diethyl maleate results in increased expression of GCLM protein
CTD
PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 PMID:33545341 PMID:34480604 More...
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
G
Gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
increases expression
ISO
diethyl maleate results in increased expression of GCNT3 mRNA
CTD
PMID:33545341
NCBI chr 8:79,570,081...79,577,389
Ensembl chr 8:70,686,844...70,699,562
G
Gdf15
growth differentiation factor 15
increases expression
ISO
diethyl maleate results in increased expression of GDF15 mRNA
CTD
PMID:33545341
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,805,239...18,808,055
G
Gdf9
growth differentiation factor 9
increases expression
ISO
diethyl maleate results in increased expression of GDF9 mRNA
CTD
PMID:33545341
NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
G
Gfod1
Gfo/Idh/MocA-like oxidoreductase domain containing 1
increases expression
ISO
diethyl maleate results in increased expression of GFOD1 mRNA
CTD
PMID:33545341
NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938
G
Glul
glutamate-ammonia ligase
decreases expression
ISO
diethyl maleate results in decreased expression of GLUL mRNA
CTD
PMID:25270620
NCBI chr13:68,519,500...68,585,554
Ensembl chr13:66,025,630...66,035,108
G
Got2
glutamic-oxaloacetic transaminase 2
decreases expression
EXP
diethyl maleate results in decreased expression of GOT2 protein
CTD
PMID:21161181
NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,174,311...9,199,994
G
Gpihbp1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
decreases expression
ISO
diethyl maleate results in decreased expression of GPIHBP1 mRNA
CTD
PMID:25270620
NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702
G
Gpx2
glutathione peroxidase 2
affects expression
ISO
diethyl maleate affects the expression of GPX2 mRNA
CTD
PMID:34480604
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:95,493,589...95,496,877
G
Gria3
glutamate ionotropic receptor AMPA type subunit 3
decreases expression
EXP
diethyl maleate results in decreased expression of GRIA3 mRNA
CTD
PMID:21161181
NCBI chr X:125,103,975...125,369,690
Ensembl chr X:120,238,534...120,504,096
G
Gsn
gelsolin
decreases reduction
ISO
diethyl maleate results in decreased reduction of GSN protein
CTD
PMID:19843705
NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402
G
Gsr
glutathione-disulfide reductase
increases expression
ISO
diethyl maleate results in increased expression of GSR mRNA
CTD
PMID:25270620
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
G
Gss
glutathione synthetase
increases expression
EXP
diethyl maleate results in increased expression of GSS mRNA
CTD
PMID:10978506
NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
G
Gsta1
glutathione S-transferase alpha 1
affects expression
ISO
diethyl maleate affects the expression of GSTA1 mRNA
CTD
PMID:34480604
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121
G
Gsta2
glutathione S-transferase alpha 2
increases expression
ISO
diethyl maleate results in increased expression of GSTA2 mRNA
CTD
PMID:25270620
NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:79,184,322...79,196,798
G
Gsta3
glutathione S-transferase alpha 3
increases expression
EXP
diethyl maleate results in increased expression of GSTA3 protein
CTD
PMID:9794803
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
G
Gsta4
glutathione S-transferase alpha 4
increases expression
ISO
diethyl maleate results in increased expression of GSTA4 mRNA
CTD
PMID:25270620
NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:79,066,934...79,084,182
G
Gsta5
glutathione S-transferase alpha 5
increases expression
EXP
diethyl maleate results in increased expression of GSTA5 protein
CTD
PMID:9794803
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
G
Gstk1
glutathione S-transferase kappa 1
multiple interactions
ISO
[diethyl maleate results in decreased abundance of Glutathione] which results in decreased expression of GSTK1 mRNA
CTD
PMID:22564015
NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:71,118,896...71,123,292
G
Gstm1
glutathione S-transferase mu 1
decreases expression
EXP
diethyl maleate results in decreased expression of GSTM1 protein
CTD
PMID:21161181
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Gsto1
glutathione S-transferase omega 1
increases expression
ISO
diethyl maleate results in increased expression of GSTO1 mRNA
CTD
PMID:25270620
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:246,721,221...246,731,468
G
Gstp1
glutathione S-transferase pi 1
increases expression
EXP
diethyl maleate results in increased expression of GSTP1 protein
CTD
PMID:9794803
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
G
Gstt1
glutathione S-transferase theta 1
increases expression
EXP
diethyl maleate results in increased expression of GSTT1 protein
CTD
PMID:9794803
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
Gtse1
G-2 and S-phase expressed 1
increases expression
EXP
diethyl maleate results in increased expression of GTSE1 mRNA
CTD
PMID:21161181
NCBI chr 7:118,829,793...118,846,662
Ensembl chr 7:116,950,053...116,966,806
G
H2az2
H2A.Z variant histone 2
increases expression
ISO
diethyl maleate results in increased expression of H2AZ2 mRNA
CTD
PMID:33545341
NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144 Ensembl chr 4:81,293,299...81,312,144 Ensembl chr16:81,293,299...81,312,144
G
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
increases expression
ISO
diethyl maleate results in increased expression of H6PD mRNA
CTD
PMID:25270620
NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
G
Hamp
hepcidin antimicrobial peptide
increases expression
ISO
diethyl maleate results in increased expression of HAMP mRNA
CTD
PMID:33545341
NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891
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Helb
DNA helicase B
decreases expression
ISO
diethyl maleate results in decreased expression of HELB mRNA
CTD
PMID:25270620
NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
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Hes6
hes family bHLH transcription factor 6
decreases expression
EXP
diethyl maleate results in decreased expression of HES6 mRNA
CTD
PMID:21161181
NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
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Hjurp
Holliday junction recognition protein
increases expression
EXP
diethyl maleate results in increased expression of HJURP mRNA
CTD
PMID:21161181
NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728
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Hmox1
heme oxygenase 1
increases expression
ISO
diethyl maleate results in increased expression of HMOX1 mRNA; diethyl maleate results in increased expression of HMOX1 protein
CTD
PMID:20491607 PMID:25270620 PMID:30261343 PMID:33545341 PMID:34480604 PMID:35724838 More...
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
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Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
decreases reduction
ISO
diethyl maleate results in decreased reduction of HNRNPH1 protein
CTD
PMID:19843705
NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
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Hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
increases expression
ISO
diethyl maleate results in increased expression of HSD17B10 mRNA
CTD
PMID:33545341
NCBI chr X:24,568,551...24,571,012
Ensembl chr X:21,089,122...21,109,488
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Hsd17b2
hydroxysteroid (17-beta) dehydrogenase 2
decreases expression
EXP
diethyl maleate results in decreased expression of HSD17B2 mRNA
CTD
PMID:21161181
NCBI chr19:62,662,320...62,733,944
Ensembl chr19:45,753,574...45,825,202
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Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
ISO
diethyl maleate results in increased expression of HSPA1B mRNA
CTD
PMID:33545341
NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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Hspa1l
heat shock protein family A (Hsp70) member 1 like
increases expression
ISO
diethyl maleate results in increased expression of HSPA1L mRNA
CTD
PMID:33545341
NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,848,843...3,855,571
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Hspa5
heat shock protein family A (Hsp70) member 5
decreases reduction
ISO
diethyl maleate results in decreased reduction of HSPA5 protein
CTD
PMID:19843705
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
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Hspa6l-ps1
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
increases expression
ISO
diethyl maleate results in increased expression of HSPA6 mRNA
CTD
PMID:33545341
NCBI chr13:85,805,911...85,807,052
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Hspa8
heat shock protein family A (Hsp70) member 8
increases reduction
ISO
diethyl maleate results in increased reduction of HSPA8 protein
CTD
PMID:19843705
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:41,183,264...41,187,259
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Htatip2
HIV-1 Tat interactive protein 2
increases expression
ISO
diethyl maleate results in increased expression of HTATIP2 mRNA
CTD
PMID:25270620
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
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Hycc2
hyccin PI4KA lipid kinase complex subunit 2
decreases expression
EXP
diethyl maleate results in decreased expression of HYCC2 mRNA
CTD
PMID:21161181
NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
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Icam1
intercellular adhesion molecule 1
decreases expression multiple interactions
ISO
diethyl maleate results in decreased expression of ICAM1 mRNA diethyl maleate inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; NFE2L2 protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]
CTD
PMID:25270620 PMID:35724838
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
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Id3
inhibitor of DNA binding 3
decreases expression
ISO
diethyl maleate results in decreased expression of ID3 mRNA
CTD
PMID:25270620
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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Id4
inhibitor of DNA binding 4
decreases expression
ISO
diethyl maleate results in decreased expression of ID4 mRNA
CTD
PMID:25270620
NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,389,387...16,392,470
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
decreases expression
EXP
diethyl maleate results in decreased expression of IFIT3 mRNA
CTD
PMID:21161181
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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Ifrd1
interferon-related developmental regulator 1
increases expression
ISO
diethyl maleate results in increased expression of IFRD1 mRNA
CTD
PMID:33545341
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
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Igtp
interferon gamma induced GTPase
decreases expression
EXP
diethyl maleate results in decreased expression of IGTP mRNA
CTD
PMID:21161181
NCBI chr10:42,374,590...42,382,410
Ensembl chr10:42,357,400...42,408,247
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Ikbke
inhibitor of nuclear factor kappa B kinase subunit epsilon
decreases expression
ISO
diethyl maleate results in decreased expression of IKBKE mRNA
CTD
PMID:25270620
NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
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Ikbkg
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
increases expression
ISO
diethyl maleate results in increased expression of IKBKG mRNA
CTD
PMID:25270620
NCBI chr X:157,358,279...157,397,563
Ensembl chr X:152,216,596...152,239,499
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Il10
interleukin 10
increases secretion
ISO
diethyl maleate results in increased secretion of IL10 protein
CTD
PMID:31958493
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
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Il18
interleukin 18
increases expression
ISO
diethyl maleate results in increased expression of IL18 protein
CTD
PMID:23063874
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
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Il1a
interleukin 1 alpha
multiple interactions
ISO
diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]
CTD
PMID:7476933
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
multiple interactions
ISO
diethyl maleate inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; diethyl maleate inhibits the reaction [IL1B protein affects the localization of RELA protein]; diethyl maleate inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; diethyl maleate inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]
CTD
PMID:35724838
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
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Il1r1
interleukin 1 receptor type 1
affects expression
ISO
diethyl maleate affects the expression of IL1R1 mRNA
CTD
PMID:34480604
NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:42,504,735...42,579,937
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Il4
interleukin 4
multiple interactions
ISO
[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein
CTD
PMID:31958493
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
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Inhbb
inhibin subunit beta B
decreases expression
ISO
diethyl maleate results in decreased expression of INHBB mRNA
CTD
PMID:25270620
NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
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Inmt
indolethylamine N-methyltransferase
decreases expression
EXP
diethyl maleate results in decreased expression of INMT mRNA
CTD
PMID:21161181
NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
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Ins2
insulin 2
multiple interactions
ISO
diethyl maleate inhibits the reaction [INS protein affects the localization of and results in increased phosphorylation of FOXO1 protein]
CTD
PMID:30261343
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775
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Ints7
integrator complex subunit 7
decreases expression
ISO
diethyl maleate results in decreased expression of INTS7 mRNA
CTD
PMID:25270620
NCBI chr13:103,155,123...103,207,953
Ensembl chr13:103,155,090...103,208,592
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Irf7
interferon regulatory factor 7
decreases expression
EXP
diethyl maleate results in decreased expression of IRF7 mRNA
CTD
PMID:21161181
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
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Irf9
interferon regulatory factor 9
decreases expression
EXP
diethyl maleate results in decreased expression of IRF9 mRNA
CTD
PMID:21161181
NCBI chr15:33,065,422...33,071,881
Ensembl chr15:29,095,789...29,101,236
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Irgm
immunity-related GTPase M
decreases expression
EXP
diethyl maleate results in decreased expression of IRGM mRNA
CTD
PMID:21161181
NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
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Itgal
integrin subunit alpha L
decreases expression
EXP
diethyl maleate results in decreased expression of ITGAL mRNA
CTD
PMID:21161181
NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
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Itih3
inter-alpha trypsin inhibitor, heavy chain 3
decreases expression
ISO
diethyl maleate results in decreased expression of ITIH3 mRNA
CTD
PMID:25270620
NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
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Itih4
inter-alpha-trypsin inhibitor heavy chain 4
decreases expression
ISO
diethyl maleate results in decreased expression of ITIH4 mRNA
CTD
PMID:25270620
NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
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Jam3
junctional adhesion molecule 3
decreases expression
EXP
diethyl maleate results in decreased expression of JAM3 mRNA
CTD
PMID:21161181
NCBI chr 8:33,767,606...33,828,451
Ensembl chr 8:25,507,057...25,569,355
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases phosphorylation increases expression
ISO
pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein] diethyl maleate results in increased expression of JUN mRNA pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of JUN protein modified form]
CTD
PMID:10915739 PMID:12774022 PMID:30261343
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
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Kcne3
potassium voltage-gated channel subfamily E regulatory subunit 3
decreases expression
ISO
diethyl maleate results in decreased expression of KCNE3 mRNA
CTD
PMID:25270620
NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
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Keap1
Kelch-like ECH-associated protein 1
increases expression
ISO
diethyl maleate results in increased expression of KEAP1 mRNA; diethyl maleate results in increased expression of KEAP1 protein
CTD
PMID:27358234 PMID:33545341 PMID:34480604
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:19,768,375...19,777,862
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Khdrbs3
KH RNA binding domain containing, signal transduction associated 3
increases expression
ISO
diethyl maleate results in increased expression of KHDRBS3 mRNA
CTD
PMID:33545341
NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460
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Kifc1
kinesin family member C1
increases expression
EXP
diethyl maleate results in increased expression of KIFC1 mRNA
CTD
PMID:21161181
NCBI chr20:5,000,929...5,018,967
Ensembl chr20:4,999,047...5,017,105
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Klf10
KLF transcription factor 10
decreases expression
EXP ISO
diethyl maleate results in decreased expression of KLF10 mRNA
CTD
PMID:21161181 PMID:25270620
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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Krt75
keratin 75
increases reduction
ISO
diethyl maleate results in increased reduction of KRT75 protein
CTD
PMID:19843705
NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345
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Lama1
laminin subunit alpha 1
decreases expression
ISO
diethyl maleate results in decreased expression of LAMA1 mRNA
CTD
PMID:25270620
NCBI chr 9:115,139,548...115,263,620
Ensembl chr 9:107,692,770...107,817,478
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Lancl2
LanC like glutathione S-transferase 2
decreases expression
ISO
diethyl maleate results in decreased expression of LANCL2 mRNA
CTD
PMID:25270620
NCBI chr 4:87,441,821...87,483,707
Ensembl chr 4:87,441,823...87,482,800
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Ldlr
low density lipoprotein receptor
decreases expression
EXP
diethyl maleate results in decreased expression of LDLR mRNA
CTD
PMID:21161181
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580
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Lepr
leptin receptor
decreases expression
EXP
diethyl maleate results in decreased expression of LEPR mRNA
CTD
PMID:21161181
NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
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Lgals3bp
galectin 3 binding protein
decreases expression
EXP
diethyl maleate results in decreased expression of LGALS3BP mRNA
CTD
PMID:21161181
NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256
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Lmnb1
lamin B1
increases expression
EXP
diethyl maleate results in increased expression of LMNB1 mRNA
CTD
PMID:21161181
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
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Lmo7
LIM domain 7
decreases expression
EXP
diethyl maleate results in decreased expression of LMO7 mRNA
CTD
PMID:21161181
NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783
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Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
decreases expression
EXP
diethyl maleate results in decreased expression of LRIG3 mRNA
CTD
PMID:21161181
NCBI chr 7:61,816,313...61,866,275
Ensembl chr 7:61,816,342...61,866,481
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Lrrn4
leucine rich repeat neuronal 4
increases expression
EXP
diethyl maleate results in increased expression of LRRN4 mRNA
CTD
PMID:21161181
NCBI chr 3:140,592,303...140,603,986
Ensembl chr 3:120,139,410...120,150,831
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Lrtm2
leucine-rich repeats and transmembrane domains 2
decreases expression
EXP
diethyl maleate results in decreased expression of LRTM2 mRNA
CTD
PMID:21161181
NCBI chr 4:152,485,863...152,508,248
Ensembl chr 4:152,485,866...152,500,377
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Ltc4s
leukotriene C4 synthase
decreases expression
EXP
diethyl maleate results in decreased expression of LTC4S mRNA
CTD
PMID:21161181
NCBI chr10:35,060,002...35,066,466
Ensembl chr10:34,560,360...34,562,651
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Lum
lumican
decreases expression
EXP
diethyl maleate results in decreased expression of LUM mRNA
CTD
PMID:21161181
NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:32,358,614...32,365,793
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Ly6c
Ly6-C antigen
decreases expression
EXP
diethyl maleate results in decreased expression of LY6C mRNA
CTD
PMID:21161181
NCBI chr 7:106,959,508...106,963,329
Ensembl chr 7:106,959,511...106,963,329
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Maff
MAF bZIP transcription factor F
increases expression
ISO
diethyl maleate results in increased expression of MAFF mRNA
CTD
PMID:20491607 PMID:33545341
NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:110,912,499...110,923,851
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Mafg
MAF bZIP transcription factor G
increases expression
ISO
diethyl maleate results in increased expression of MAFG mRNA
CTD
PMID:33545341 PMID:34480604
NCBI chr10:106,401,633...106,410,159
Ensembl chr10:105,903,237...105,912,026
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Maoa
monoamine oxidase A
increases expression
ISO
diethyl maleate results in increased expression of MAOA mRNA
CTD
PMID:25270620
NCBI chr X:8,615,239...8,681,372
Ensembl chr X:6,030,795...6,099,593
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Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
increases expression
ISO
diethyl maleate results in increased expression of MAPK1IP1L mRNA
CTD
PMID:33545341
NCBI chr15:20,545,043...20,571,466
Ensembl chr15:20,545,059...20,569,674
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Mapk8
mitogen-activated protein kinase 8
increases expression multiple interactions
ISO
diethyl maleate results in increased expression of MAPK8 protein modified form pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of MAPK8 protein modified form]
CTD
PMID:30261343
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
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Mapk9
mitogen-activated protein kinase 9
multiple interactions increases expression
ISO
pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of MAPK9 protein modified form]
CTD
PMID:30261343
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178
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Marveld1
MARVEL domain containing 1
decreases expression
EXP
diethyl maleate results in decreased expression of MARVELD1 mRNA
CTD
PMID:21161181
NCBI chr 1:240,954,050...240,958,101
Ensembl chr 1:240,954,452...240,958,384
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Mboat7
membrane bound O-acyltransferase domain containing 7
increases expression
ISO
diethyl maleate results in increased expression of MBOAT7 mRNA
CTD
PMID:33545341
NCBI chr 1:74,440,618...74,454,896
Ensembl chr 1:65,525,213...65,539,538
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Mcm10
minichromosome maintenance 10 replication initiation factor
increases expression
EXP
diethyl maleate results in increased expression of MCM10 mRNA
CTD
PMID:21161181
NCBI chr17:78,172,049...78,197,644
Ensembl chr17:73,266,095...73,287,364
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Mcm4
minichromosome maintenance complex component 4
increases expression
EXP
diethyl maleate results in increased expression of MCM4 mRNA
CTD
PMID:21161181
NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
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Me1
malic enzyme 1
increases expression
ISO
diethyl maleate results in increased expression of ME1 mRNA
CTD
PMID:25270620
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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Mfap4
microfibril associated protein 4
decreases expression
EXP
diethyl maleate results in decreased expression of MFAP4 mRNA
CTD
PMID:21161181
NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155
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Mgmt
O-6-methylguanine-DNA methyltransferase
decreases activity
ISO
diethyl maleate results in decreased activity of MGMT protein
CTD
PMID:16950796
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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Mki67
marker of proliferation Ki-67
increases expression
EXP
diethyl maleate results in increased expression of MKI67 mRNA
CTD
PMID:21161181
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762
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Mknk2
MAPK interacting serine/threonine kinase 2
decreases expression
EXP
diethyl maleate results in decreased expression of MKNK2 mRNA
CTD
PMID:21161181
NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,039,728...9,050,827
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Mmp1
matrix metallopeptidase 1
increases expression
ISO
diethyl maleate results in increased expression of MMP1 mRNA
CTD
PMID:33545341
NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097
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Mmp12
matrix metallopeptidase 12
increases expression
ISO
diethyl maleate results in increased expression of MMP12 mRNA
CTD
PMID:10216232
NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:4,581,785...4,599,611
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Mmp2
matrix metallopeptidase 2
decreases expression
EXP
diethyl maleate results in decreased expression of MMP2 mRNA
CTD
PMID:21161181
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870
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Mmp3
matrix metallopeptidase 3
increases expression
ISO
diethyl maleate results in increased expression of MMP3 mRNA
CTD
PMID:33545341
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961
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Mpzl1
myelin protein zero-like 1
decreases expression
ISO
diethyl maleate results in decreased expression of MPZL1 mRNA
CTD
PMID:34480604
NCBI chr13:80,385,454...80,422,315
Ensembl chr13:77,852,467...77,896,616
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Msn
moesin
increases reduction
ISO
diethyl maleate results in increased reduction of MSN protein
CTD
PMID:19843705
NCBI chr X:60,996,043...61,064,011
Ensembl chr X:60,995,951...61,065,628
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Mt1
metallothionein 1
increases expression
ISO
diethyl maleate results in increased expression of MT1A mRNA
CTD
PMID:20491607
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
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Mt2
metallothionein 2
increases expression
ISO
diethyl maleate results in increased expression of MT2A mRNA
CTD
PMID:20491607
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784
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Mx1
MX dynamin like GTPase 1
decreases expression
EXP
diethyl maleate results in decreased expression of MX1 mRNA
CTD
PMID:21161181
NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
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Mx2
MX dynamin like GTPase 2
decreases expression
EXP
diethyl maleate results in decreased expression of MX2 mRNA
CTD
PMID:21161181
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
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Mybl2
MYB proto-oncogene like 2
increases expression
EXP
diethyl maleate results in increased expression of MYBL2 mRNA
CTD
PMID:21161181
NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
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Mycn
MYCN proto-oncogene, bHLH transcription factor
decreases expression
ISO
diethyl maleate results in decreased expression of MYCN mRNA
CTD
PMID:25270620
NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:35,717,764...35,723,590
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Nat8
N-acetyltransferase 8
decreases expression
EXP
diethyl maleate results in decreased expression of NAT8 mRNA
CTD
PMID:21161181
NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
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Ncaph
non-SMC condensin I complex, subunit H
increases expression
EXP
diethyl maleate results in increased expression of NCAPH mRNA
CTD
PMID:21161181
NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:114,371,941...114,399,180
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Ndrg1
N-myc downstream regulated 1
increases expression
ISO
diethyl maleate results in increased expression of NDRG1 mRNA
CTD
PMID:33545341
NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:98,684,487...98,725,880
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Nfe2l2
NFE2 like bZIP transcription factor 2
affects localization multiple interactions decreases response to substance increases expression increases activity
ISO EXP
diethyl maleate affects the localization of NFE2L2 protein NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA] NFE2L2 results in decreased susceptibility to diethyl maleate diethyl maleate results in increased expression of NFE2L2 protein [diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein; diethyl maleate binds to and results in increased activity of NFE2L2 protein; diethyl maleate promotes the reaction [NFE2L2 protein binds to SMPD1 promoter]; diethyl maleate results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SMPD1 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; NFE2L2 protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]; RELA protein inhibits the reaction [diethyl maleate results in increased expression of NFE2L2 protein]; RELA protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]; TNFAIP3 protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein] diethyl maleate results in increased activity of NFE2L2 protein
CTD
PMID:12235164 PMID:20806931 PMID:21465251 PMID:22003191 PMID:25762726 PMID:27358234 PMID:27982581 PMID:30114225 PMID:34021431 PMID:35724838 More...
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
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Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA] diethyl maleate inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; diethyl maleate inhibits the reaction [TNF protein affects the localization of NFKBIA protein]
CTD
PMID:12774022 PMID:35724838
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941
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Nherf1
NHERF family PDZ scaffold protein 1
decreases expression
EXP
diethyl maleate results in decreased expression of NHERF1 mRNA
CTD
PMID:21161181
NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
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Nos2
nitric oxide synthase 2
multiple interactions
EXP ISO
Acetylcysteine inhibits the reaction [diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate]
CTD
PMID:7532384 PMID:9918918 PMID:12774022
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
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Notch1
notch receptor 1
increases expression
ISO
diethyl maleate results in increased expression of NOTCH1 mRNA
CTD
PMID:33545341
NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
diethyl maleate results in increased expression of NQO1 mRNA
CTD
PMID:20491607 PMID:25270620 PMID:33545341 PMID:34480604
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
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Nr0b2
nuclear receptor subfamily 0, group B, member 2
decreases expression
EXP
diethyl maleate results in decreased expression of NR0B2 mRNA
CTD
PMID:21161181
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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Nr1d1
nuclear receptor subfamily 1, group D, member 1
decreases expression
EXP
diethyl maleate results in decreased expression of NR1D1 mRNA
CTD
PMID:21161181
NCBI chr10:84,224,599...84,231,812
Ensembl chr10:83,728,318...83,735,705
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Nrep
neuronal regeneration related protein
decreases expression
EXP
diethyl maleate results in decreased expression of NREP mRNA
CTD
PMID:21161181
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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Nsmf
NMDA receptor synaptonuclear signaling and neuronal migration factor
decreases expression
ISO
diethyl maleate results in decreased expression of NSMF mRNA
CTD
PMID:25270620
NCBI chr 3:7,861,846...7,870,615
Ensembl chr 3:7,861,872...7,870,614
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Ntf3
neurotrophin 3
decreases expression
EXP
diethyl maleate results in decreased expression of NTF3 mRNA
CTD
PMID:21161181
NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:158,914,957...158,984,596
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Nup153
nucleoporin 153
multiple interactions affects localization
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; diethyl maleate results in increased phosphorylation of and results in increased O-linked glycosylation of NUP153 protein
CTD
PMID:20041180
NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876
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Nup88
nucleoporin 88
multiple interactions affects localization
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] affects the reaction [diethyl maleate affects the localization of NUP88 protein]; diethyl maleate results in increased phosphorylation of and results in increased glycosylation of NUP88 protein
CTD
PMID:20041180
NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
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Oaf
out at first homolog
decreases expression
EXP
diethyl maleate results in decreased expression of OAF mRNA
CTD
PMID:21161181
NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
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Oas1a
2'-5' oligoadenylate synthetase 1A
decreases expression
EXP
diethyl maleate results in decreased expression of OAS1A mRNA
CTD
PMID:21161181
NCBI chr12:41,330,423...41,341,130
Ensembl chr12:35,669,801...35,680,517
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Oas1b
2-5 oligoadenylate synthetase 1B
decreases expression
EXP
diethyl maleate results in decreased expression of OAS1B mRNA
CTD
PMID:21161181
NCBI chr12:35,724,561...35,735,271
Ensembl chr12:35,724,055...35,735,242
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Oas1i
2 ' -5 ' oligoadenylate synthetase 1I
decreases expression
EXP
diethyl maleate results in decreased expression of OAS1I mRNA
CTD
PMID:21161181
NCBI chr12:35,624,566...35,636,608
Ensembl chr12:35,624,592...35,636,604
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Ogg1
8-oxoguanine DNA glycosylase
multiple interactions
ISO
[diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of OGG1 mRNA
CTD
PMID:22564015
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
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Orc1
origin recognition complex, subunit 1
increases expression
EXP
diethyl maleate results in increased expression of ORC1 mRNA
CTD
PMID:21161181
NCBI chr 5:128,552,975...128,581,943
Ensembl chr 5:123,324,315...123,348,375
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Osgin1
oxidative stress induced growth inhibitor 1
increases expression
ISO
diethyl maleate results in increased expression of OSGIN1 mRNA
CTD
PMID:33545341
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
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P2rx7
purinergic receptor P2X 7
decreases expression
EXP
diethyl maleate results in decreased expression of P2RX7 mRNA
CTD
PMID:21161181
NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
diethyl maleate results in increased cleavage of PARP1 protein
CTD
PMID:21105742
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
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Pbld1
phenazine biosynthesis-like protein domain containing 1
decreases expression
EXP
diethyl maleate results in decreased expression of PBLD protein
CTD
PMID:21161181
NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
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Pcna
proliferating cell nuclear antigen
decreases expression
ISO
diethyl maleate results in decreased expression of PCNA mRNA
CTD
PMID:11875189
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995
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Pdlim2
PDZ and LIM domain 2
decreases expression
EXP
diethyl maleate results in decreased expression of PDLIM2 mRNA
CTD
PMID:21161181
NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
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Pdrg1
p53 and DNA damage regulated 1
increases expression
ISO
diethyl maleate results in increased expression of PDRG1 mRNA
CTD
PMID:25270620
NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858 Ensembl chr 3:141,476,501...141,483,858
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Per2
period circadian regulator 2
decreases expression
EXP
diethyl maleate results in decreased expression of PER2 mRNA
CTD
PMID:21161181
NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
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Per3
period circadian regulator 3
decreases expression
EXP
diethyl maleate results in decreased expression of PER3 mRNA
CTD
PMID:21161181
NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
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Pgd
phosphogluconate dehydrogenase
increases activity
EXP
diethyl maleate results in increased activity of PGD protein
CTD
PMID:3099627
NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:159,561,271...159,742,778
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Pgrmc1
progesterone receptor membrane component 1
increases expression
ISO
diethyl maleate results in increased expression of PGRMC1 mRNA
CTD
PMID:25270620
NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682
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Pir
pirin
increases expression
ISO
diethyl maleate results in increased expression of PIR mRNA
CTD
PMID:25270620
NCBI chr X:33,740,428...33,851,049
Ensembl chr X:30,108,538...30,219,218
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Pklr
pyruvate kinase L/R
decreases expression
EXP
diethyl maleate results in decreased expression of PKLR mRNA
CTD
PMID:21161181
NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:174,543,039...174,551,870
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Plat
plasminogen activator, tissue type
increases expression decreases expression
EXP ISO
diethyl maleate results in increased expression of PLAT mRNA diethyl maleate results in decreased expression of PLAT mRNA
CTD
PMID:21161181 PMID:25270620
NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223
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Plek
pleckstrin
decreases expression
EXP
diethyl maleate results in decreased expression of PLEK mRNA
CTD
PMID:21161181
NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
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Plekhm1
pleckstrin homology and RUN domain containing M1
increases expression
ISO
diethyl maleate results in increased expression of PLEKHM1 mRNA
CTD
PMID:33545341
NCBI chr10:88,313,837...88,366,182
Ensembl chr10:88,314,651...88,362,412
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Plin2
perilipin 2
increases expression
ISO
diethyl maleate results in increased expression of PLIN2 mRNA
CTD
PMID:33545341
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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Plk1
polo-like kinase 1
increases expression
ISO
diethyl maleate results in increased expression of PLK1 mRNA
CTD
PMID:33545341
NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:176,716,420...176,726,400
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Plk3
polo-like kinase 3
increases expression
ISO
diethyl maleate results in increased expression of PLK3 mRNA
CTD
PMID:33545341
NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:130,607,142...130,612,317
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Pou5f1
POU class 5 homeobox 1
increases expression
ISO
diethyl maleate results in increased expression of POU5F1 mRNA
CTD
PMID:33545341
NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,223,129...3,227,891
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Ppara
peroxisome proliferator activated receptor alpha
multiple interactions decreases activity
EXP
diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol inhibits the reaction [diethyl maleate results in decreased activity of PPARA protein]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate results in decreased activity of PPARA protein]
CTD
PMID:17134953
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
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Ppargc1b
PPARG coactivator 1 beta
decreases expression
EXP
diethyl maleate results in decreased expression of PPARGC1B mRNA
CTD
PMID:21161181
NCBI chr18:57,029,264...57,131,466
Ensembl chr18:54,758,902...54,861,194
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Ppp1r3b
protein phosphatase 1, regulatory subunit 3B
decreases expression
EXP
diethyl maleate results in decreased expression of PPP1R3B mRNA
CTD
PMID:21161181
NCBI chr16:63,533,318...63,545,683
Ensembl chr16:56,829,660...56,842,406
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Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
decreases expression
EXP
diethyl maleate results in decreased expression of PPP1R3C mRNA
CTD
PMID:21161181
NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:234,460,652...234,465,961
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Prdm14
PR/SET domain 14
decreases expression
ISO
diethyl maleate results in decreased expression of PRDM14 mRNA
CTD
PMID:25270620
NCBI chr 5:10,864,137...10,876,666
Ensembl chr 5:6,082,442...6,092,712
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Prdx1
peroxiredoxin 1
increases expression
EXP ISO
diethyl maleate results in increased expression of PRDX1 mRNA
CTD
PMID:9506838
NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:130,147,204...130,162,856
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Prkab1
protein kinase AMP-activated non-catalytic subunit beta 1
decreases expression
ISO
diethyl maleate results in decreased expression of PRKAB1 mRNA
CTD
PMID:25270620
NCBI chr12:46,248,971...46,259,487
Ensembl chr12:40,588,211...40,598,661
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Prkag2
protein kinase AMP-activated non-catalytic subunit gamma 2
increases expression
ISO
diethyl maleate results in increased expression of PRKAG2 mRNA
CTD
PMID:33545341
NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,010,890...10,252,142
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Prkcb
protein kinase C, beta
affects expression
ISO
diethyl maleate affects the expression of PRKCB protein
CTD
PMID:31958493
NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:176,832,226...177,163,536
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Prkcd
protein kinase C, delta
multiple interactions
EXP
Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCD protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCD protein
CTD
PMID:11118818
NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352
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Prkce
protein kinase C, epsilon
multiple interactions
EXP
Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCE protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCE protein
CTD
PMID:11118818
NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:7,965,048...8,451,719
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Prss8
serine protease 8
decreases expression
EXP
diethyl maleate results in decreased expression of PRSS8 mRNA
CTD
PMID:21161181
NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815
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Ptgr1
prostaglandin reductase 1
increases expression
ISO
diethyl maleate results in increased expression of PTGR1 mRNA
CTD
PMID:25270620
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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Ptpn14
protein tyrosine phosphatase, non-receptor type 14
increases expression
ISO
diethyl maleate results in increased expression of PTPN14 mRNA
CTD
PMID:25270620
NCBI chr13:101,268,258...101,420,508
Ensembl chr13:101,268,416...101,414,088
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Pus1
pseudouridine synthase 1
decreases expression
ISO
diethyl maleate results in decreased expression of PUS1 mRNA
CTD
PMID:25270620
NCBI chr12:45,880,364...45,889,196
Ensembl chr12:45,880,440...45,889,196
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Pxn
paxillin
increases expression
ISO
diethyl maleate results in increased expression of PXN mRNA
CTD
PMID:33545341
NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931
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Rab27a
RAB27A, member RAS oncogene family
decreases expression
EXP
diethyl maleate results in decreased expression of RAB27A mRNA
CTD
PMID:21161181
NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]]; diethyl maleate inhibits the reaction [IL1B protein affects the localization of RELA protein]; diethyl maleate inhibits the reaction [TNF protein affects the localization of RELA protein]; RELA protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]]; RELA protein inhibits the reaction [diethyl maleate results in increased expression of NFE2L2 protein]; RELA protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]; RELA protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]
CTD
PMID:20116392 PMID:35724838
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
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Rho
rhodopsin
increases expression
ISO
diethyl maleate results in increased expression of RHO mRNA
CTD
PMID:33545341
NCBI chr 4:148,975,597...148,988,693
Ensembl chr 4:148,980,611...148,985,773
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Rnf114
ring finger protein 114
decreases expression
ISO
diethyl maleate results in decreased expression of RNF114 mRNA
CTD
PMID:25270620
NCBI chr 3:156,222,487...156,234,263
Ensembl chr 3:156,222,498...156,234,256
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Rnf14
ring finger protein 14
increases expression
ISO
diethyl maleate results in increased expression of RNF14 mRNA
CTD
PMID:25270620
NCBI chr18:30,131,627...30,155,686
Ensembl chr18:30,131,691...30,155,685
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Rrm2
ribonucleotide reductase regulatory subunit M2
increases expression
EXP ISO
diethyl maleate results in increased expression of RRM2 mRNA
CTD
PMID:21161181 PMID:33545341
NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:41,340,557...41,346,773
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Rsad2
radical S-adenosyl methionine domain containing 2
decreases expression
EXP
diethyl maleate results in decreased expression of RSAD2 mRNA
CTD
PMID:21161181
NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:43,047,658...43,059,699
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RT1-S3
RT1 class Ib, locus S3
decreases expression
EXP
diethyl maleate results in decreased expression of RT1-S3 mRNA
CTD
PMID:21161181
NCBI chr20:2,675,463...2,680,229
Ensembl chr20:2,670,709...2,675,411
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S100a9
S100 calcium binding protein A9
decreases expression
EXP
diethyl maleate results in decreased expression of S100A9 mRNA
CTD
PMID:21161181
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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Sash3
SAM and SH3 domain containing 3
decreases expression
EXP
diethyl maleate results in decreased expression of SASH3 mRNA
CTD
PMID:21161181
NCBI chr X:132,204,717...132,219,421
Ensembl chr X:127,326,859...127,341,519
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Scarb1
scavenger receptor class B, member 1
decreases expression
ISO
diethyl maleate results in decreased expression of SCARB1 mRNA
CTD
PMID:34480604
NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647
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Scd
stearoyl-CoA desaturase
decreases expression
EXP
diethyl maleate results in decreased expression of SCD1 mRNA
CTD
PMID:21161181
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
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Sds
serine dehydratase
decreases expression
EXP
diethyl maleate results in decreased expression of SDS mRNA
CTD
PMID:21161181
NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
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Selenop
selenoprotein P
decreases expression
ISO
diethyl maleate results in decreased expression of SELENOP mRNA
CTD
PMID:30261343
NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:52,498,339...52,508,852
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Serpind1
serpin family D member 1
decreases expression
ISO
diethyl maleate results in decreased expression of SERPIND1 mRNA
CTD
PMID:25270620
NCBI chr11:97,168,753...97,179,830
Ensembl chr11:83,664,518...83,675,519
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Sertad1
SERTA domain containing 1
increases expression
ISO
diethyl maleate results in increased expression of SERTAD1 mRNA
CTD
PMID:33545341
NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091
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Sez6
seizure related 6 homolog
decreases expression
EXP
diethyl maleate results in decreased expression of SEZ6 mRNA
CTD
PMID:21161181
NCBI chr10:62,818,931...62,868,686
Ensembl chr10:62,819,069...62,868,671
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Sfxn1
sideroflexin 1
decreases expression
ISO
diethyl maleate results in decreased expression of SFXN1 mRNA
CTD
PMID:25270620
NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
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Sh3bp5
SH3-domain binding protein 5
increases expression affects expression
ISO
diethyl maleate results in increased expression of SH3BP5 mRNA diethyl maleate affects the expression of SH3BP5 mRNA
CTD
PMID:33545341 PMID:34480604
NCBI chr16:6,589,877...6,676,524
Ensembl chr16:6,583,465...6,698,975
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Six4
SIX homeobox 4
increases expression
ISO
diethyl maleate results in increased expression of SIX4 mRNA
CTD
PMID:25270620
NCBI chr 6:91,802,328...91,816,002
Ensembl chr 6:91,802,329...91,815,992
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Slc16a6
solute carrier family 16, member 6
decreases expression
ISO
diethyl maleate results in decreased expression of SLC16A6 mRNA
CTD
PMID:25270620
NCBI chr10:94,923,888...94,946,990
Ensembl chr10:94,426,244...94,448,779
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Slc1a4
solute carrier family 1 member 4
increases expression
ISO
diethyl maleate results in increased expression of SLC1A4 mRNA
CTD
PMID:25270620
NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
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Slc2a2
solute carrier family 2 member 2
decreases expression
EXP
diethyl maleate results in decreased expression of SLC2A2 mRNA
CTD
PMID:21161181
NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:111,611,774...111,639,933
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Slc2a5
solute carrier family 2 member 5
decreases expression
EXP
diethyl maleate results in decreased expression of SLC2A5 mRNA
CTD
PMID:21161181
NCBI chr 5:165,857,412...165,892,928
Ensembl chr 5:160,583,234...160,611,106
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Slc39a14
solute carrier family 39 member 14
decreases expression
ISO
diethyl maleate results in decreased expression of SLC39A14 mRNA
CTD
PMID:25270620
NCBI chr15:51,786,517...51,833,260
Ensembl chr15:45,376,917...45,423,524
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Slc3a2
solute carrier family 3 member 2
increases expression
ISO
diethyl maleate results in increased expression of SLC3A2 mRNA
CTD
PMID:33545341
NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931
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Slc40a1
solute carrier family 40 member 1
multiple interactions
ISO
diethyl maleate inhibits the reaction [Lipopolysaccharides results in decreased expression of SLC40A1 mRNA]
CTD
PMID:21303654
NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:48,033,526...48,051,481
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Slc44a4
solute carrier family 44, member 4
decreases expression
EXP
diethyl maleate results in decreased expression of SLC44A4 mRNA
CTD
PMID:21161181
NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
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Slc7a11
solute carrier family 7 member 11
multiple interactions increases expression
ISO
NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA]
CTD
PMID:12235164 PMID:33545341
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Slco2a1
solute carrier organic anion transporter family, member 2a1
decreases expression
EXP
diethyl maleate results in decreased expression of SLCO2A1 mRNA
CTD
PMID:21161181
NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546
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Slfn3
schlafen 3
decreases expression
EXP
diethyl maleate results in decreased expression of SLFN3 mRNA
CTD
PMID:21161181
NCBI chr10:68,020,482...68,060,248
Ensembl chr10:68,055,355...68,060,603
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Smc4
structural maintenance of chromosomes 4
increases expression
EXP
diethyl maleate results in increased expression of SMC4 mRNA
CTD
PMID:21161181
NCBI chr 2:155,550,262...155,578,695
Ensembl chr 2:153,240,283...153,271,571
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Smpd1
sphingomyelin phosphodiesterase 1
increases expression increases activity multiple interactions
ISO
diethyl maleate results in increased expression of SMPD1 mRNA diethyl maleate results in increased activity of SMPD1 protein Dactinomycin inhibits the reaction [diethyl maleate results in increased expression of SMPD1 mRNA]; diethyl maleate promotes the reaction [NFE2L2 protein binds to SMPD1 promoter]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SMPD1 mRNA]
CTD
PMID:25762726
NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
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Smtn
smoothelin
increases expression
EXP
diethyl maleate results in increased expression of SMTN mRNA
CTD
PMID:21161181
NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886
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Socs3
suppressor of cytokine signaling 3
decreases expression
ISO
diethyl maleate results in decreased expression of SOCS3 mRNA
CTD
PMID:25270620
NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,193,537...103,197,787
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Sod2
superoxide dismutase 2
multiple interactions
ISO
diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein]
CTD
PMID:7476933
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
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Sorl1
sortilin related receptor 1
decreases expression
EXP
diethyl maleate results in decreased expression of SORL1 mRNA
CTD
PMID:21161181
NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:42,341,704...42,504,513
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Sox9
SRY-box transcription factor 9
increases expression
EXP
diethyl maleate results in increased expression of SOX9 mRNA
CTD
PMID:21161181
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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Sp5
Sp5 transcription factor
decreases expression
ISO
diethyl maleate results in decreased expression of SP5 mRNA
CTD
PMID:25270620
NCBI chr 3:55,274,931...55,277,733
Ensembl chr 3:55,274,931...55,277,733
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Spc25
SPC25 component of NDC80 kinetochore complex
increases expression
EXP
diethyl maleate results in increased expression of SPC25 mRNA
CTD
PMID:21161181
NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
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Spta1
spectrin, alpha, erythrocytic 1
increases expression
ISO
diethyl maleate results in increased expression of SPTA1 mRNA
CTD
PMID:25270620
NCBI chr13:86,203,504...86,279,371
Ensembl chr13:86,203,504...86,279,371
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Sptan1
spectrin, alpha, non-erythrocytic 1
increases cleavage
ISO
diethyl maleate results in increased cleavage of SPTAN1 protein
CTD
PMID:21105742
NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
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Sptbn4
spectrin, beta, non-erythrocytic 4
increases expression
ISO
diethyl maleate results in increased expression of SPTBN4 mRNA
CTD
PMID:25270620
NCBI chr 1:91,778,379...91,865,970
Ensembl chr 1:82,650,751...82,737,228
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Sptlc1
serine palmitoyltransferase, long chain base subunit 1
increases expression
ISO
diethyl maleate results in increased expression of SPTLC1 mRNA
CTD
PMID:33545341
NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295
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Sqstm1
sequestosome 1
increases expression
ISO
diethyl maleate results in increased expression of SQSTM1 mRNA
CTD
PMID:25270620 PMID:33545341 PMID:34480604
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673
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Srebf1
sterol regulatory element binding transcription factor 1
decreases expression
EXP
diethyl maleate results in decreased expression of SREBF1 mRNA
CTD
PMID:21161181
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
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Srxn1
sulfiredoxin 1
multiple interactions increases expression decreases expression
ISO
[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA] diethyl maleate results in increased expression of SRXN1 mRNA; diethyl maleate results in increased expression of SRXN1 protein [diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; NFE2L2 protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]; RELA protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; RELA protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]; TNFAIP3 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein] diethyl maleate results in decreased expression of SRXN1 mRNA
CTD
PMID:22003191 PMID:25270620 PMID:27358234 PMID:27982581 PMID:33545341 PMID:34480604 PMID:34626751 PMID:35724838 More...
NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:140,599,608...140,628,448
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Stat1
signal transducer and activator of transcription 1
decreases expression
EXP
diethyl maleate results in decreased expression of STAT1 mRNA
CTD
PMID:21161181
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:49,419,340...49,588,540
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Steap4
STEAP4 metalloreductase
decreases expression
ISO
diethyl maleate results in decreased expression of STEAP4 mRNA
CTD
PMID:25270620
NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859
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Sulf2
sulfatase 2
decreases expression
EXP
diethyl maleate results in decreased expression of SULF2 mRNA
CTD
PMID:21161181
NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
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Sult1a1
sulfotransferase family 1A member 1
decreases expression
EXP
diethyl maleate results in decreased expression of SULT1A1 protein
CTD
PMID:21161181
NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:181,272,023...181,275,562
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Tagln
transgelin
decreases expression
EXP
diethyl maleate results in decreased expression of TAGLN mRNA
CTD
PMID:21161181
NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
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Tatdn2
TatD DNase domain containing 2
increases expression
ISO
diethyl maleate results in increased expression of TATDN2 mRNA
CTD
PMID:33545341
NCBI chr 4:146,845,156...146,865,708
Ensembl chr 4:146,845,156...146,860,897
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Tbcel
tubulin folding cofactor E-like
increases expression
ISO
diethyl maleate results in increased expression of TBCEL mRNA
CTD
PMID:25270620
NCBI chr 8:42,795,648...42,854,552
Ensembl chr 8:42,796,730...42,854,552
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Tent4a
terminal nucleotidyltransferase 4A
increases expression
ISO
diethyl maleate results in increased expression of TENT4A mRNA
CTD
PMID:33545341
NCBI chr 1:33,765,949...33,799,405
Ensembl chr 1:33,765,672...33,799,433
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Tent5a
terminal nucleotidyltransferase 5A
decreases expression
EXP
diethyl maleate results in decreased expression of TENT5A mRNA
CTD
PMID:21161181
NCBI chr 8:95,102,349...95,109,100
Ensembl chr 8:86,225,357...86,229,045
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Tesmin
testis expressed metallothionein like protein
affects localization
ISO
diethyl maleate affects the localization of TESMIN protein
CTD
PMID:12606435
NCBI chr 1:210,059,414...210,077,704
Ensembl chr 1:200,630,144...200,648,433
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Tf
transferrin
decreases expression
EXP
diethyl maleate results in decreased expression of TF protein
CTD
PMID:21161181
NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511
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Tfeb
transcription factor EB
decreases expression
ISO
diethyl maleate results in decreased expression of TFEB mRNA
CTD
PMID:25270620
NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
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Tgm2
transglutaminase 2
increases expression
EXP
diethyl maleate results in increased expression of TGM2 mRNA
CTD
PMID:21161181
NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
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Thbs1
thrombospondin 1
increases expression
EXP
diethyl maleate results in increased expression of THBS1 mRNA
CTD
PMID:21161181
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
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Thrsp
thyroid hormone responsive
decreases expression
EXP
diethyl maleate results in decreased expression of THRSP mRNA
CTD
PMID:21161181
NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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Tm4sf1
transmembrane 4 L six family member 1
increases expression
EXP
diethyl maleate results in increased expression of TM4SF1 mRNA
CTD
PMID:21161181
NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
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Tmem209
transmembrane protein 209
increases expression
ISO
diethyl maleate results in increased expression of TMEM209 mRNA
CTD
PMID:25270620
NCBI chr 4:59,102,943...59,128,636
Ensembl chr 4:59,101,550...59,128,630
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Tnf
tumor necrosis factor
multiple interactions
ISO EXP
[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein; [diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein; diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]]; diethyl maleate inhibits the reaction [TNF protein affects the localization of NFKBIA protein]; diethyl maleate inhibits the reaction [TNF protein affects the localization of RELA protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; NFE2L2 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]]; RELA protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]; TNFAIP3 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; TNFAIP3 protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein] diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein] diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate]
CTD
PMID:7476933 PMID:7532384 PMID:12774022 PMID:20116392 PMID:31958493 PMID:35724838 More...
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
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Tnfaip3
TNF alpha induced protein 3
multiple interactions
ISO
diethyl maleate inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]]; TNFAIP3 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; TNFAIP3 protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]
CTD
PMID:35724838
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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Tnfrsf14
TNF receptor superfamily member 14
decreases expression
EXP
diethyl maleate results in decreased expression of TNFRSF14 mRNA
CTD
PMID:21161181
NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703
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Tp53
tumor protein p53
multiple interactions
ISO
TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA] TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
CTD
PMID:22003191 PMID:27982581
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
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Tpm2
tropomyosin 2
decreases expression
EXP
diethyl maleate results in decreased expression of TPM2 mRNA
CTD
PMID:21161181
NCBI chr 5:62,566,712...62,576,066
Ensembl chr 5:57,770,864...57,779,992
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Trap1
TNF receptor-associated protein 1
multiple interactions decreases response to substance
ISO
diethyl maleate inhibits the reaction [Cisplatin results in decreased expression of TRAP1 protein] TRAP1 protein results in decreased susceptibility to diethyl maleate
CTD
PMID:17853063
NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
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Trdmt1
tRNA aspartic acid methyltransferase 1
decreases expression
ISO
diethyl maleate results in decreased expression of TRDMT1 mRNA
CTD
PMID:25270620
NCBI chr17:81,510,740...81,554,036
Ensembl chr17:76,610,543...76,645,439
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Trib1
tribbles pseudokinase 1
increases expression
ISO
diethyl maleate results in increased expression of TRIB1 mRNA
CTD
PMID:33545341
NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:91,206,579...91,214,731
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Trib3
tribbles pseudokinase 3
increases expression
ISO
diethyl maleate results in increased expression of TRIB3 mRNA
CTD
PMID:33545341
NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497
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Trim6
tripartite motif containing 6
decreases expression
EXP
diethyl maleate results in decreased expression of TRIM6 mRNA
CTD
PMID:21161181
NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
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Trip13
thyroid hormone receptor interactor 13
increases expression
EXP
diethyl maleate results in increased expression of TRIP13 mRNA
CTD
PMID:21161181
NCBI chr 1:31,185,700...31,230,638
Ensembl chr 1:29,357,130...29,402,074
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Tsc22d1
TSC22 domain family, member 1
decreases expression
EXP
diethyl maleate results in decreased expression of TSC22D1 mRNA
CTD
PMID:21161181
NCBI chr15:58,159,612...58,260,244
Ensembl chr15:51,749,510...51,850,958
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Tspan8
tetraspanin 8
decreases expression
EXP
diethyl maleate results in decreased expression of TSPAN8 mRNA
CTD
PMID:21161181
NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356
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Tstd1
thiosulfate sulfurtransferase like domain containing 1
decreases expression
ISO
diethyl maleate results in decreased expression of TSTD1 mRNA
CTD
PMID:25270620
NCBI chr13:83,853,421...83,854,875
Ensembl chr13:83,822,035...83,854,885
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Txn1
thioredoxin 1
decreases activity
ISO
diethyl maleate results in decreased activity of TXN protein
CTD
PMID:15388247
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629
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Txnip
thioredoxin interacting protein
increases expression
EXP
diethyl maleate results in increased expression of TXNIP mRNA
CTD
PMID:21161181
NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
diethyl maleate results in increased expression of TXNRD1 mRNA
CTD
PMID:15521073 PMID:33545341 PMID:34480604
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863
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Ubd
ubiquitin D
decreases expression
EXP
diethyl maleate results in decreased expression of UBD mRNA
CTD
PMID:21161181
NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
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Uhrf1
ubiquitin-like with PHD and ring finger domains 1
increases expression
EXP
diethyl maleate results in increased expression of UHRF1 mRNA
CTD
PMID:21161181
NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,134,909...1,154,631
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Usp18
ubiquitin specific peptidase 18
decreases expression
EXP
diethyl maleate results in decreased expression of USP18 mRNA
CTD
PMID:21161181
NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
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Usp2
ubiquitin specific peptidase 2
decreases expression
EXP
diethyl maleate results in decreased expression of USP2 mRNA
CTD
PMID:21161181
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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Vegfa
vascular endothelial growth factor A
increases expression
ISO
diethyl maleate results in increased expression of VEGFA mRNA
CTD
PMID:33545341
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641
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Wdr31
WD repeat domain 31
decreases expression
ISO
diethyl maleate results in decreased expression of WDR31 mRNA
CTD
PMID:25270620
NCBI chr 5:75,897,074...75,917,461
Ensembl chr 5:75,898,353...75,917,417
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Wdr6
WD repeat domain 6
decreases expression
EXP
diethyl maleate results in decreased expression of WDR6 mRNA
CTD
PMID:21161181
NCBI chr 8:118,146,608...118,153,024
Ensembl chr 8:109,268,079...109,274,499
G
Ypel5
yippee-like 5
increases expression
ISO
diethyl maleate results in increased expression of YPEL5 mRNA
CTD
PMID:25270620
NCBI chr 6:28,408,079...28,423,536
Ensembl chr 6:22,656,285...22,671,691
G
Zfand2a
zinc finger AN1-type containing 2A
increases expression
ISO
diethyl maleate results in increased expression of ZFAND2A mRNA
CTD
PMID:33545341 PMID:34480604
NCBI chr12:20,275,435...20,286,513
Ensembl chr12:15,161,639...15,172,677
G
Zfp36
zinc finger protein 36
increases expression
ISO
diethyl maleate results in increased expression of ZFP36 protein
CTD
PMID:21969073
NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:83,669,084...83,671,564
G
Zfp367
zinc finger protein 367
increases expression
EXP
diethyl maleate results in increased expression of ZNF367 mRNA
CTD
PMID:21161181
NCBI chr17:970,896...990,025
Ensembl chr17:965,161...984,287
G
Zfp37
zinc finger protein 37
decreases expression
EXP
diethyl maleate results in decreased expression of ZFP37 mRNA
CTD
PMID:21161181
NCBI chr 5:75,598,732...75,638,896
Ensembl chr 5:75,598,732...75,638,942
G
Znrd2
zinc ribbon domain containing 2
decreases expression
ISO
diethyl maleate results in decreased expression of ZNRD2 mRNA
CTD
PMID:25270620
NCBI chr 1:203,017,682...203,019,465
Ensembl chr 1:203,017,682...203,019,465
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