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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:diethyl maleate
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Accession:CHEBI:68508 term browser browse the term
Definition:A maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. A colourless liquid at room temperature (m.p. -10degreeC) with boiling point 220degreeC at 1 atm., it is commonly used as a dienophile for Diels-Alder-type cycloaddition reactions in organic synthesis.
Synonyms:exact_synonym: diethyl (2Z)-but-2-enedioate
 related_synonym: 2-butenedioic acid (2Z)-, dimethyl ester;   Formula=C8H12O4;   InChI=1S/C8H12O4/c1-3-11-7(9)5-6-8(10)12-4-2/h5-6H,3-4H2,1-2H3/b6-5-;   InChIKey=IEPRKVQEAMIZSS-WAYWQWQTSA-N;   SMILES=CCOC(=O)\\C=C/C(=O)OCC;   maleic acid, diethyl ester
 xref: CAS:141-05-9
 xref_mesh: MESH:C014476
 xref: PMID:1471155;   PMID:1609410;   PMID:3341033;   Reaxys:907616



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diethyl maleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 increases expression EXP diethyl maleate results in increased expression of ABCC2 mRNA CTD PMID:25270620 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abhd4 abhydrolase domain containing 4 increases expression EXP diethyl maleate results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr14:54,491,586...54,506,626
Ensembl chr14:54,491,645...54,508,094
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha decreases expression EXP diethyl maleate results in decreased expression of ACACA mRNA CTD PMID:25270620 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions ISO diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]] CTD PMID:17134953 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Acy3 aminoacylase 3 decreases expression ISO diethyl maleate results in decreased expression of ACY3 mRNA CTD PMID:21161181 NCBI chr19:4,036,570...4,040,007
Ensembl chr19:4,036,570...4,040,007
JBrowse link
G Adm adrenomedullin increases expression ISO diethyl maleate results in increased expression of ADM mRNA CTD PMID:33545341 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027
JBrowse link
G Adora3 adenosine A3 receptor decreases expression ISO diethyl maleate results in decreased expression of ADORA3 mRNA CTD PMID:21161181 NCBI chr 3:105,811,737...105,816,244
Ensembl chr 3:105,778,174...105,816,242
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO diethyl maleate results in increased expression of AEN mRNA CTD PMID:33545341 NCBI chr 7:78,545,675...78,560,957
Ensembl chr 7:78,545,602...78,560,957
JBrowse link
G Afp alpha fetoprotein increases expression EXP diethyl maleate results in increased expression of AFP mRNA CTD PMID:25270620 NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
JBrowse link
G Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 increases expression EXP diethyl maleate results in increased expression of AHCYL1 mRNA CTD PMID:25270620 NCBI chr 3:107,570,436...107,603,876
Ensembl chr 3:107,570,434...107,603,876
JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 increases expression ISO diethyl maleate results in increased expression of AKR1A1 protein CTD PMID:21161181 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877
JBrowse link
G Akr1b10 aldo-keto reductase family 1, member B10 increases expression ISO diethyl maleate results in increased expression of AKR1B10 mRNA CTD PMID:33545341 NCBI chr 6:34,361,182...34,373,884
Ensembl chr 6:34,361,153...34,373,885
JBrowse link
G Akr1c19 aldo-keto reductase family 1, member C19 increases expression EXP diethyl maleate results in increased expression of AKR1C19 mRNA CTD PMID:25270620 NCBI chr13:4,283,499...4,298,360
Ensembl chr13:4,278,699...4,302,842
JBrowse link
G Akr1c21 aldo-keto reductase family 1, member C21 increases expression ISO diethyl maleate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 affects reduction EXP diethyl maleate affects the reduction of ALDH1A1 protein CTD PMID:19843705 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression ISO diethyl maleate results in decreased expression of ALDH1B1 mRNA CTD PMID:21161181 NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial decreases reduction
decreases expression
increases expression
EXP
ISO
diethyl maleate results in decreased reduction of ALDH2 protein
diethyl maleate results in decreased expression of ALDH2 protein
diethyl maleate results in increased expression of ALDH2 protein
CTD PMID:19843705 PMID:21161181 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Aldob aldolase B, fructose-bisphosphate decreases expression ISO diethyl maleate results in decreased expression of ALDOB protein CTD PMID:21161181 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression ISO diethyl maleate results in decreased expression of AMIGO2 mRNA CTD PMID:21161181 NCBI chr15:97,141,955...97,145,168
Ensembl chr15:97,142,006...97,145,168
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO diethyl maleate results in decreased expression of ANGPTL2 mRNA CTD PMID:21161181 NCBI chr 2:33,105,963...33,137,737
Ensembl chr 2:33,106,081...33,137,729
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO diethyl maleate results in increased expression of ANGPTL4 mRNA CTD PMID:33545341 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
JBrowse link
G Ankrd46 ankyrin repeat domain 46 decreases expression ISO diethyl maleate results in decreased expression of ANKRD46 mRNA CTD PMID:21161181 NCBI chr15:36,477,814...36,496,937
Ensembl chr15:36,477,814...36,496,966
JBrowse link
G Anln anillin, actin binding protein increases expression ISO diethyl maleate results in increased expression of ANLN mRNA CTD PMID:21161181 NCBI chr 9:22,243,305...22,302,132
Ensembl chr 9:22,243,308...22,300,484
JBrowse link
G Anxa1 annexin A1 affects expression ISO diethyl maleate affects the expression of ANXA1 mRNA CTD PMID:34480604 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Anxa3 annexin A3 decreases expression ISO diethyl maleate results in decreased expression of ANXA3 mRNA CTD PMID:21161181 NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825
JBrowse link
G Ap3m2 adaptor-related protein complex 3, mu 2 subunit decreases expression ISO diethyl maleate results in decreased expression of AP3M2 mRNA CTD PMID:21161181 NCBI chr 8:23,277,370...23,297,308
Ensembl chr 8:23,277,370...23,295,638
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO diethyl maleate results in increased expression of APAF1 mRNA CTD PMID:11875189 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Aplp1 amyloid beta precursor like protein 1 decreases expression EXP diethyl maleate results in decreased expression of APLP1 mRNA CTD PMID:25270620 NCBI chr 7:30,134,405...30,144,960
Ensembl chr 7:30,134,407...30,144,960
JBrowse link
G Apol9a apolipoprotein L 9a decreases expression ISO diethyl maleate results in decreased expression of APOL9A mRNA CTD PMID:21161181 NCBI chr15:77,287,989...77,295,280
Ensembl chr15:77,287,989...77,295,335
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 increases expression ISO diethyl maleate results in increased expression of ARHGAP9 mRNA CTD PMID:33545341 NCBI chr10:127,157,829...127,165,816
Ensembl chr10:127,157,833...127,165,812
JBrowse link
G Arrdc2 arrestin domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of ARRDC2 mRNA CTD PMID:21161181 NCBI chr 8:71,287,773...71,293,173
Ensembl chr 8:71,287,773...71,292,364
JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression EXP diethyl maleate results in decreased expression of ARRDC4 mRNA CTD PMID:25270620 NCBI chr 7:68,386,742...68,398,986
Ensembl chr 7:68,386,743...68,398,989
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone increases expression ISO diethyl maleate results in increased expression of ASF1B mRNA CTD PMID:21161181 NCBI chr 8:84,682,323...84,696,824
Ensembl chr 8:84,682,136...84,696,826
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 decreases expression EXP diethyl maleate results in decreased expression of ASXL1 mRNA CTD PMID:25270620 NCBI chr 2:153,187,750...153,245,927
Ensembl chr 2:153,187,749...153,245,927
JBrowse link
G Atm ataxia telangiectasia mutated increases expression ISO diethyl maleate results in increased expression of ATM mRNA CTD PMID:11875189 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression ISO diethyl maleate results in increased expression of ATP5F1B protein CTD PMID:21161181 NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260
JBrowse link
G Aurka aurora kinase A increases expression
decreases expression
ISO
EXP
diethyl maleate results in increased expression of AURKA mRNA
diethyl maleate results in decreased expression of AURKA mRNA
CTD PMID:21161181 PMID:25270620 NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455
JBrowse link
G Bbc3 BCL2 binding component 3 increases expression ISO diethyl maleate results in increased expression of BBC3 mRNA CTD PMID:33545341 NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
increases expression
EXP
ISO
[diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of BCL2 mRNA
diethyl maleate results in increased expression of BCL2 mRNA
CTD PMID:22564015 PMID:33545341 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b decreases expression ISO diethyl maleate results in decreased expression of BCL2A1 mRNA CTD PMID:21161181 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 decreases expression EXP diethyl maleate results in decreased expression of BCL3 mRNA CTD PMID:25270620 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
JBrowse link
G Bcl6b B cell CLL/lymphoma 6, member B decreases expression ISO diethyl maleate results in decreased expression of BCL6B mRNA CTD PMID:21161181 NCBI chr11:70,114,953...70,120,624
Ensembl chr11:70,114,954...70,120,624
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 decreases expression ISO diethyl maleate results in decreased expression of BHLHE41 mRNA CTD PMID:21161181 NCBI chr 6:145,803,969...145,811,146
Ensembl chr 6:145,803,969...145,811,284
JBrowse link
G Bhmt betaine-homocysteine methyltransferase decreases expression ISO diethyl maleate results in decreased expression of BHMT mRNA CTD PMID:21161181 NCBI chr13:93,753,399...93,774,266
Ensembl chr13:93,753,183...93,774,469
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions EXP diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA] CTD PMID:12774022 NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187
JBrowse link
G Blvrb biliverdin reductase B increases expression EXP diethyl maleate results in increased expression of BLVRB mRNA CTD PMID:25270620 PMID:34626751 NCBI chr 7:27,147,403...27,165,406
Ensembl chr 7:27,147,403...27,165,569
JBrowse link
G Bmf BCL2 modifying factor decreases expression ISO diethyl maleate results in decreased expression of BMF mRNA CTD PMID:21161181 NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168
JBrowse link
G Brip1 BRCA1 interacting protein C-terminal helicase 1 increases expression ISO diethyl maleate results in increased expression of BRIP1 mRNA CTD PMID:21161181 NCBI chr11:85,948,957...86,092,041
Ensembl chr11:85,948,964...86,092,019
JBrowse link
G Btbd2 BTB domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of BTBD2 mRNA CTD PMID:21161181 NCBI chr10:80,478,457...80,492,328
Ensembl chr10:80,478,451...80,492,328
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression
multiple interactions
decreases expression
EXP diethyl maleate results in increased expression of BTG2 mRNA
NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]
diethyl maleate results in decreased expression of BTG2 mRNA
CTD PMID:22003191 PMID:25270620 PMID:34626751 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
JBrowse link
G C6 complement component 6 decreases expression ISO diethyl maleate results in decreased expression of C6 mRNA CTD PMID:21161181 NCBI chr15:4,756,550...4,833,527
Ensembl chr15:4,756,657...4,844,449
JBrowse link
G Casp2 caspase 2 increases expression ISO diethyl maleate results in increased expression of CASP2 mRNA CTD PMID:11875189 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
ISO diethyl maleate results in increased expression of CASP3 mRNA
diethyl maleate results in increased cleavage of CASP3 protein
CTD PMID:11875189 PMID:21105742 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 increases expression ISO diethyl maleate results in increased expression of CASP9 mRNA CTD PMID:11875189 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase decreases expression ISO diethyl maleate results in decreased expression of CAT protein CTD PMID:21161181 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression EXP diethyl maleate results in increased expression of CBR1 mRNA CTD PMID:25270620 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression
multiple interactions
ISO
EXP
diethyl maleate results in increased expression of CBR3 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diethyl maleate results in increased expression of CBR3 mRNA]
CTD PMID:20806931 PMID:25270620 NCBI chr16:93,480,107...93,487,879
Ensembl chr16:93,480,103...93,487,878
JBrowse link
G Cbx4 chromobox 4 increases expression ISO diethyl maleate results in increased expression of CBX4 mRNA CTD PMID:33545341 NCBI chr11:118,968,399...118,977,067
Ensembl chr11:118,968,399...118,977,047
JBrowse link
G Ccdc50 coiled-coil domain containing 50 decreases expression EXP diethyl maleate results in decreased expression of CCDC50 mRNA CTD PMID:25270620 NCBI chr16:27,205,815...27,270,968
Ensembl chr16:27,207,619...27,270,968
JBrowse link
G Ccna1 cyclin A1 decreases expression ISO diethyl maleate results in decreased expression of CCNA1 mRNA CTD PMID:11875189 NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922
JBrowse link
G Ccna2 cyclin A2 increases expression ISO diethyl maleate results in increased expression of CCNA2 mRNA CTD PMID:21161181 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression
ISO
EXP
diethyl maleate results in decreased expression of CCND1 mRNA
diethyl maleate results in increased expression of CCND1 mRNA
CTD PMID:11875189 PMID:21161181 PMID:25270620 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccne2 cyclin E2 increases expression ISO diethyl maleate results in increased expression of CCNE2 mRNA CTD PMID:21161181 NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
JBrowse link
G Ccnk cyclin K decreases expression ISO diethyl maleate results in decreased expression of CCNK mRNA CTD PMID:11875189 NCBI chr12:108,145,543...108,170,252
Ensembl chr12:108,145,838...108,169,618
JBrowse link
G Cd80 CD80 antigen multiple interactions
increases expression
ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein
diethyl maleate results in increased expression of CD80 protein
CTD PMID:31958493 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
JBrowse link
G Cd86 CD86 antigen multiple interactions
increases expression
ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; bisindolylmaleimide I inhibits the reaction [diethyl maleate results in increased expression of CD86 protein] CTD PMID:24136171 PMID:31958493 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Cdc25a cell division cycle 25A increases expression ISO diethyl maleate results in increased expression of CDC25A mRNA CTD PMID:21161181 NCBI chr 9:109,704,545...109,722,963
Ensembl chr 9:109,704,647...109,722,963
JBrowse link
G Cdca2 cell division cycle associated 2 increases expression ISO diethyl maleate results in increased expression of CDCA2 mRNA CTD PMID:21161181 NCBI chr14:67,910,629...67,953,290
Ensembl chr14:67,913,780...67,953,290
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression ISO diethyl maleate results in increased expression of CDCA3 mRNA CTD PMID:21161181 NCBI chr 6:124,806,533...124,810,664
Ensembl chr 6:124,806,510...124,810,664
JBrowse link
G Cdca8 cell division cycle associated 8 increases expression ISO diethyl maleate results in increased expression of CDCA8 mRNA CTD PMID:21161181 NCBI chr 4:124,812,258...124,830,710
Ensembl chr 4:124,812,258...124,833,104
JBrowse link
G Cdh11 cadherin 11 decreases expression ISO diethyl maleate results in decreased expression of CDH11 mRNA CTD PMID:21161181 NCBI chr 8:103,358,727...103,512,125
Ensembl chr 8:103,358,727...103,512,274
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression
multiple interactions
ISO diethyl maleate results in increased expression of CDKN1A mRNA; diethyl maleate results in increased expression of CDKN1A protein
TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]
CTD PMID:11875189 PMID:27982581 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cds2 CDP-diacylglycerol synthase 2 increases expression EXP diethyl maleate results in increased expression of CDS2 mRNA CTD PMID:25270620 NCBI chr 2:132,105,068...132,153,970
Ensembl chr 2:132,105,068...132,153,970
JBrowse link
G Ces1d carboxylesterase 1D increases reduction
decreases expression
EXP
ISO
diethyl maleate results in increased reduction of CES1D protein
diethyl maleate results in decreased expression of CES1D protein
CTD PMID:19843705 PMID:21161181 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Ces2a carboxylesterase 2A increases reduction EXP diethyl maleate results in increased reduction of CES2A protein CTD PMID:19843705 NCBI chr 8:105,460,635...105,468,266
Ensembl chr 8:105,460,635...105,468,266
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO diethyl maleate results in decreased expression of CFLAR mRNA CTD PMID:21161181 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 increases expression ISO diethyl maleate results in increased expression of CHRNA4 mRNA CTD PMID:33545341 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
JBrowse link
G Cidec cell death-inducing DFFA-like effector c decreases expression ISO diethyl maleate results in decreased expression of CIDEC mRNA CTD PMID:21161181 NCBI chr 6:113,401,595...113,412,721
Ensembl chr 6:113,401,595...113,412,721
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression ISO diethyl maleate results in decreased expression of CITED2 mRNA CTD PMID:21161181 NCBI chr10:17,598,452...17,601,422
Ensembl chr10:17,598,966...17,601,422
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression ISO diethyl maleate results in decreased expression of CITED4 mRNA CTD PMID:21161181 NCBI chr 4:120,523,760...120,525,017
Ensembl chr 4:120,523,769...120,525,017
JBrowse link
G Ckb creatine kinase, brain decreases reduction EXP diethyl maleate results in decreased reduction of CKB protein CTD PMID:19843705 NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO diethyl maleate results in increased expression of CKS2 mRNA CTD PMID:33545341 NCBI chr13:51,799,268...51,804,698
Ensembl chr13:51,799,268...51,804,696
JBrowse link
G Clk1 CDC-like kinase 1 increases expression ISO diethyl maleate results in increased expression of CLK1 mRNA CTD PMID:33545341 NCBI chr 1:58,451,147...58,463,247
Ensembl chr 1:58,449,348...58,463,225
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO diethyl maleate results in decreased expression of CMPK2 mRNA CTD PMID:21161181 NCBI chr12:26,519,121...26,529,836
Ensembl chr12:26,519,203...26,529,836
JBrowse link
G Cntn1 contactin 1 increases expression ISO diethyl maleate results in increased expression of CNTN1 mRNA CTD PMID:33545341 NCBI chr15:91,949,034...92,239,834
Ensembl chr15:91,949,046...92,239,848
JBrowse link
G Col1a1 collagen, type I, alpha 1 decreases expression ISO diethyl maleate results in decreased expression of COL1A1 mRNA CTD PMID:21161181 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Col3a1 collagen, type III, alpha 1 decreases expression EXP diethyl maleate results in decreased expression of COL3A1 mRNA CTD PMID:25270620 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
JBrowse link
G Commd3 COMM domain containing 3 increases expression EXP diethyl maleate results in increased expression of COMMD3 mRNA CTD PMID:25270620 NCBI chr 2:18,677,246...18,681,042
Ensembl chr 2:18,677,234...18,681,042
JBrowse link
G Comt catechol-O-methyltransferase decreases expression ISO diethyl maleate results in decreased expression of COMT mRNA CTD PMID:21161181 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Cp ceruloplasmin decreases expression EXP diethyl maleate results in decreased expression of CP mRNA CTD PMID:25270620 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
JBrowse link
G Cpsf4l cleavage and polyadenylation specific factor 4-like increases expression ISO diethyl maleate results in increased expression of CPSF4L mRNA CTD PMID:33545341 NCBI chr11:113,588,997...113,601,125
Ensembl chr11:113,588,998...113,600,843
JBrowse link
G Crym crystallin, mu decreases expression ISO diethyl maleate results in decreased expression of CRYM mRNA CTD PMID:21161181 NCBI chr 7:119,785,603...119,801,212
Ensembl chr 7:119,785,603...119,801,334
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression ISO diethyl maleate results in decreased expression of CSRP1 mRNA CTD PMID:21161181 NCBI chr 1:135,614,650...135,679,970
Ensembl chr 1:135,647,799...135,679,970
JBrowse link
G Csrp3 cysteine and glycine-rich protein 3 decreases reduction EXP diethyl maleate results in decreased reduction of CSRP3 protein CTD PMID:19843705 NCBI chr 7:48,480,146...48,497,799
Ensembl chr 7:48,480,146...48,497,781
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO diethyl maleate results in decreased expression of CXCL10 mRNA CTD PMID:21161181 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO diethyl maleate results in decreased expression of CXCL12 mRNA CTD PMID:21161181 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression
increases stability
increases secretion
multiple interactions
ISO diethyl maleate results in increased expression of CXCL8 mRNA; diethyl maleate results in increased expression of CXCL8 protein
diethyl maleate results in increased stability of CXCL8 mRNA
diethyl maleate results in increased secretion of CXCL8 protein
bisindolylmaleimide I inhibits the reaction [diethyl maleate results in increased expression of CXCL8 protein]
CTD PMID:20491607 PMID:20541004 PMID:21920952 PMID:21969073 PMID:24136171 More... NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression ISO diethyl maleate results in decreased expression of CXCL9 mRNA CTD PMID:21161181 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938
JBrowse link
G Cyb5a cytochrome b5 type A (microsomal) increases expression EXP diethyl maleate results in increased expression of CYB5A mRNA CTD PMID:25270620 NCBI chr18:84,869,463...84,897,996
Ensembl chr18:84,856,829...84,897,996
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression ISO diethyl maleate results in decreased expression of CYP26B1 mRNA CTD PMID:21161181 NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890
JBrowse link
G D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5 decreases expression EXP diethyl maleate results in decreased expression of D17H6S56E-5 mRNA CTD PMID:25270620 NCBI chr17:35,215,654...35,219,722
Ensembl chr17:35,215,654...35,219,393
JBrowse link
G Dbp D site albumin promoter binding protein decreases expression ISO diethyl maleate results in decreased expression of DBP mRNA CTD PMID:21161181 NCBI chr 7:45,354,658...45,359,579
Ensembl chr 7:45,354,512...45,359,627
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO diethyl maleate results in increased expression of DDIT3 mRNA; diethyl maleate results in increased expression of DDIT3 protein CTD PMID:33545341 PMID:35724838 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO diethyl maleate results in increased expression of DDIT4 mRNA CTD PMID:33545341 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression EXP diethyl maleate results in increased expression of DDIT4L mRNA CTD PMID:25270620 NCBI chr 3:137,329,433...137,334,093
Ensembl chr 3:137,327,373...137,334,094
JBrowse link
G Ddx60 DExD/H box helicase 60 decreases expression ISO diethyl maleate results in decreased expression of DDX60 mRNA CTD PMID:21161181 NCBI chr 8:62,381,155...62,491,278
Ensembl chr 8:62,381,121...62,491,278
JBrowse link
G Dhx58 DExH-box helicase 58 decreases expression ISO diethyl maleate results in decreased expression of DHX58 mRNA CTD PMID:21161181 NCBI chr11:100,585,710...100,595,165
Ensembl chr11:100,585,710...100,595,097
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO diethyl maleate results in increased expression of DNAJB1 mRNA CTD PMID:33545341 PMID:34480604 NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO diethyl maleate results in increased expression of DNAJB4 mRNA CTD PMID:33545341 NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939
JBrowse link
G Dnmbp dynamin binding protein decreases expression ISO diethyl maleate results in decreased expression of DNMBP mRNA CTD PMID:21161181 NCBI chr19:43,835,259...43,930,930
Ensembl chr19:43,835,260...43,928,630
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases reduction EXP diethyl maleate results in decreased reduction of DPYSL2 protein CTD PMID:19843705 NCBI chr14:67,040,313...67,148,490
Ensembl chr14:67,040,313...67,106,137
JBrowse link
G Dtx3l deltex 3-like, E3 ubiquitin ligase decreases expression ISO diethyl maleate results in decreased expression of DTX3L mRNA CTD PMID:21161181 NCBI chr16:35,746,885...35,759,397
Ensembl chr16:35,746,881...35,759,521
JBrowse link
G Dus3l dihydrouridine synthase 3 like decreases expression EXP diethyl maleate results in decreased expression of DUS3L mRNA CTD PMID:25270620 NCBI chr17:57,069,224...57,077,093
Ensembl chr17:57,071,757...57,077,093
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO diethyl maleate results in increased expression of DUSP6 mRNA CTD PMID:33545341 NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO diethyl maleate results in decreased expression of EEF2K mRNA CTD PMID:21161181 NCBI chr 7:120,442,080...120,506,441
Ensembl chr 7:120,442,054...120,506,673
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression ISO diethyl maleate results in increased expression of EGLN3 mRNA CTD PMID:34480604 NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 decreases expression ISO diethyl maleate results in decreased expression of EIF2AK2 mRNA CTD PMID:21161181 NCBI chr17:79,157,933...79,190,001
Ensembl chr17:79,159,993...79,190,002
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression EXP diethyl maleate results in increased expression of ENTPD5 mRNA CTD PMID:25270620 NCBI chr12:84,420,649...84,455,803
Ensembl chr12:84,420,631...84,455,803
JBrowse link
G Eras ES cell-expressed Ras decreases expression EXP diethyl maleate results in decreased expression of ERAS mRNA CTD PMID:25270620 NCBI chr  X:7,790,515...7,794,846
Ensembl chr  X:7,790,515...7,794,846
JBrowse link
G Ercc6l excision repair cross-complementing rodent repair deficiency complementation group 6 like increases expression ISO diethyl maleate results in increased expression of ERCC6L mRNA CTD PMID:21161181 NCBI chr  X:101,186,426...101,200,697
Ensembl chr  X:101,185,322...101,200,697
JBrowse link
G Exo1 exonuclease 1 increases expression ISO diethyl maleate results in increased expression of EXO1 mRNA CTD PMID:21161181 NCBI chr 1:175,708,334...175,738,962
Ensembl chr 1:175,708,147...175,741,055
JBrowse link
G Fabp1 fatty acid binding protein 1, liver increases expression ISO diethyl maleate results in increased expression of FABP1 protein CTD PMID:21161181 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Fabp7 fatty acid binding protein 7, brain decreases expression ISO diethyl maleate results in decreased expression of FABP7 mRNA CTD PMID:21161181 NCBI chr10:57,661,019...57,664,546
Ensembl chr10:57,660,977...57,664,546
JBrowse link
G Fah fumarylacetoacetate hydrolase affects expression ISO diethyl maleate affects the expression of FAH mRNA CTD PMID:34480604 NCBI chr 7:84,234,367...84,255,150
Ensembl chr 7:84,234,367...84,255,930
JBrowse link
G Fam83d family with sequence similarity 83, member D increases expression ISO diethyl maleate results in increased expression of FAM83D mRNA CTD PMID:33545341 NCBI chr 2:158,610,011...158,628,557
Ensembl chr 2:158,610,013...158,628,557
JBrowse link
G Fasn fatty acid synthase decreases expression ISO diethyl maleate results in decreased expression of FASN mRNA CTD PMID:21161181 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fbn1 fibrillin 1 decreases expression ISO diethyl maleate results in decreased expression of FBN1 mRNA CTD PMID:21161181 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913
JBrowse link
G Fbp1 fructose bisphosphatase 1 decreases expression ISO diethyl maleate results in decreased expression of FBP1 protein CTD PMID:21161181 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096
JBrowse link
G Fgf17 fibroblast growth factor 17 decreases expression EXP diethyl maleate results in decreased expression of FGF17 mRNA CTD PMID:25270620 NCBI chr14:70,873,643...70,880,064
Ensembl chr14:70,873,643...70,879,708
JBrowse link
G Fgg fibrinogen gamma chain decreases expression EXP diethyl maleate results in decreased expression of FGG mRNA CTD PMID:25270620 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases expression ISO diethyl maleate results in decreased expression of FGR mRNA CTD PMID:21161181 NCBI chr 4:132,701,406...132,729,204
Ensembl chr 4:132,701,406...132,729,221
JBrowse link
G Fndc3b fibronectin type III domain containing 3B decreases expression EXP diethyl maleate results in decreased expression of FNDC3B mRNA CTD PMID:25270620 NCBI chr 3:27,470,284...27,765,469
Ensembl chr 3:27,470,311...27,765,456
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression EXP
ISO
diethyl maleate results in increased expression of FOS mRNA CTD PMID:10915739 PMID:33545341 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO diethyl maleate inhibits the reaction [INS protein affects the localization of and results in increased phosphorylation of FOXO1 protein] CTD PMID:30261343 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Foxo3 forkhead box O3 increases expression ISO diethyl maleate results in increased expression of FOXO3 mRNA CTD PMID:33545341 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
JBrowse link
G Fstl3 follistatin-like 3 increases expression ISO diethyl maleate results in increased expression of FSTL3 mRNA CTD PMID:33545341 NCBI chr10:79,613,108...79,618,464
Ensembl chr10:79,613,106...79,618,464
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO
EXP
diethyl maleate results in decreased expression of G6PC1 mRNA CTD PMID:25270620 PMID:30261343 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked increases activity
increases expression
ISO diethyl maleate results in increased activity of G6PD protein
diethyl maleate results in increased expression of G6PD mRNA
CTD PMID:3099627 PMID:30261343 PMID:33545341 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gab1 growth factor receptor bound protein 2-associated protein 1 decreases expression EXP diethyl maleate results in decreased expression of GAB1 mRNA CTD PMID:25270620 NCBI chr 8:81,491,060...81,607,151
Ensembl chr 8:81,491,067...81,607,148
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression ISO diethyl maleate results in increased expression of GADD45A mRNA CTD PMID:33545341 PMID:34480604 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma increases expression ISO diethyl maleate results in increased expression of GADD45G mRNA CTD PMID:33545341 NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases reduction EXP diethyl maleate results in increased reduction of GAPDH protein CTD PMID:19843705 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
JBrowse link
G Gba2 glucosidase beta 2 decreases expression EXP diethyl maleate results in decreased expression of GBA2 mRNA CTD PMID:25270620 NCBI chr 4:43,566,928...43,578,893
Ensembl chr 4:43,566,928...43,578,873
JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO diethyl maleate results in decreased expression of GBP2 mRNA CTD PMID:21161181 NCBI chr 3:142,326,424...142,343,769
Ensembl chr 3:142,326,363...142,343,769
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases activity
increases expression
EXP
ISO
diethyl maleate results in increased activity of GCLC protein
diethyl maleate results in increased expression of GCLC mRNA; diethyl maleate results in increased expression of GCLC protein
CTD PMID:10915739 PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 More... NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO
EXP
diethyl maleate results in increased expression of GCLM mRNA; diethyl maleate results in increased expression of GCLM protein CTD PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 PMID:33545341 More... NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO diethyl maleate results in increased expression of GCNT3 mRNA CTD PMID:33545341 NCBI chr 9:69,938,777...69,947,172
Ensembl chr 9:69,938,778...69,945,370
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO diethyl maleate results in increased expression of GDF15 mRNA CTD PMID:33545341 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO diethyl maleate results in increased expression of GDF9 mRNA CTD PMID:33545341 NCBI chr11:53,321,773...53,328,731
Ensembl chr11:53,321,850...53,328,731
JBrowse link
G Gfod1 glucose-fructose oxidoreductase domain containing 1 increases expression ISO diethyl maleate results in increased expression of GFOD1 mRNA CTD PMID:33545341 NCBI chr13:43,348,716...43,457,648
Ensembl chr13:43,348,721...43,457,648
JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP diethyl maleate results in decreased expression of GLUL mRNA CTD PMID:25270620 NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial decreases expression ISO diethyl maleate results in decreased expression of GOT2 protein CTD PMID:21161181 NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
JBrowse link
G Gpihbp1 GPI-anchored HDL-binding protein 1 decreases expression EXP diethyl maleate results in decreased expression of GPIHBP1 mRNA CTD PMID:25270620 NCBI chr15:75,468,479...75,470,062
Ensembl chr15:75,468,477...75,471,330
JBrowse link
G Gpx2 glutathione peroxidase 2 affects expression ISO diethyl maleate affects the expression of GPX2 mRNA CTD PMID:34480604 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) decreases expression ISO diethyl maleate results in decreased expression of GRIA3 mRNA CTD PMID:21161181 NCBI chr  X:40,489,351...40,767,478
Ensembl chr  X:40,489,731...40,767,478
JBrowse link
G Gsn gelsolin decreases reduction EXP diethyl maleate results in decreased reduction of GSN protein CTD PMID:19843705 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904
JBrowse link
G Gsr glutathione reductase increases expression EXP diethyl maleate results in increased expression of GSR mRNA CTD PMID:25270620 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gss glutathione synthetase increases expression ISO diethyl maleate results in increased expression of GSS mRNA CTD PMID:10978506 NCBI chr 2:155,405,101...155,434,730
Ensembl chr 2:155,405,101...155,434,730
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) increases expression ISO diethyl maleate results in increased expression of GSTA5 protein CTD PMID:9794803 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Gsta2 glutathione S-transferase, alpha 2 (Yc2) increases expression EXP diethyl maleate results in increased expression of GSTA2 mRNA CTD PMID:25270620 NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions EXP [diethyl maleate results in decreased abundance of Glutathione] which results in decreased expression of GSTK1 mRNA CTD PMID:22564015 NCBI chr 6:42,222,869...42,227,375
Ensembl chr 6:42,222,869...42,227,381
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 decreases expression ISO diethyl maleate results in decreased expression of GSTM1 protein CTD PMID:21161181 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression EXP diethyl maleate results in increased expression of GSTO1 mRNA CTD PMID:25270620 NCBI chr19:47,843,412...47,853,229
Ensembl chr19:47,843,409...47,853,229
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression ISO diethyl maleate results in increased expression of GSTP1 protein CTD PMID:9794803 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 increases expression ISO diethyl maleate results in increased expression of GSTT1 protein CTD PMID:9794803 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G Gtse1 G two S phase expressed protein 1 increases expression ISO diethyl maleate results in increased expression of GTSE1 mRNA CTD PMID:21161181 NCBI chr15:85,743,928...85,760,774
Ensembl chr15:85,743,946...85,760,774
JBrowse link
G H2az2 H2A.Z histone variant 2 increases expression ISO diethyl maleate results in increased expression of H2AZ2 mRNA CTD PMID:33545341 NCBI chr11:6,377,226...6,394,511
Ensembl chr11:6,377,229...6,394,443
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) increases expression EXP diethyl maleate results in increased expression of H6PD mRNA CTD PMID:25270620 NCBI chr 4:150,063,931...150,093,480
Ensembl chr 4:150,063,932...150,093,480
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression ISO diethyl maleate results in increased expression of HAMP mRNA CTD PMID:33545341 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Helb helicase (DNA) B decreases expression EXP diethyl maleate results in decreased expression of HELB mRNA CTD PMID:25270620 NCBI chr10:119,919,513...119,948,917
Ensembl chr10:119,919,513...119,948,892
JBrowse link
G Hes6 hairy and enhancer of split 6 decreases expression ISO diethyl maleate results in decreased expression of HES6 mRNA CTD PMID:21161181 NCBI chr 1:91,339,204...91,342,901
Ensembl chr 1:91,339,205...91,341,760
JBrowse link
G Hjurp Holliday junction recognition protein increases expression ISO diethyl maleate results in increased expression of HJURP mRNA CTD PMID:21161181 NCBI chr 1:88,186,578...88,205,366
Ensembl chr 1:88,190,193...88,205,355
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO
EXP
diethyl maleate results in increased expression of HMOX1 mRNA; diethyl maleate results in increased expression of HMOX1 protein CTD PMID:20491607 PMID:25270620 PMID:30261343 PMID:33545341 PMID:34480604 More... NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases reduction EXP diethyl maleate results in decreased reduction of HNRNPH1 protein CTD PMID:19843705 NCBI chr11:50,266,084...50,277,355
Ensembl chr11:50,267,817...50,277,355
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 increases expression ISO diethyl maleate results in increased expression of HSD17B10 mRNA CTD PMID:33545341 NCBI chr  X:150,784,892...150,787,438
Ensembl chr  X:150,784,841...150,787,438
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression ISO diethyl maleate results in decreased expression of HSD17B2 mRNA CTD PMID:21161181 NCBI chr 8:118,427,752...118,485,767
Ensembl chr 8:118,428,643...118,485,766
JBrowse link
G Hspa1b heat shock protein 1B increases expression ISO diethyl maleate results in increased expression of HSPA1B mRNA CTD PMID:33545341 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
JBrowse link
G Hspa1l heat shock protein 1-like increases expression ISO diethyl maleate results in increased expression of HSPA1L mRNA CTD PMID:33545341 NCBI chr17:35,191,679...35,198,204
Ensembl chr17:35,191,679...35,198,261
JBrowse link
G Hspa5 heat shock protein 5 decreases reduction EXP diethyl maleate results in decreased reduction of HSPA5 protein CTD PMID:19843705 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Hspa8 heat shock protein 8 increases reduction EXP diethyl maleate results in increased reduction of HSPA8 protein CTD PMID:19843705 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression EXP diethyl maleate results in increased expression of HTATIP2 mRNA CTD PMID:25270620 NCBI chr 7:49,408,761...49,423,748
Ensembl chr 7:49,408,863...49,423,723
JBrowse link
G Hycc2 hyccin PI4KA lipid kinase complex subunit 2 decreases expression ISO diethyl maleate results in decreased expression of HYCC2 mRNA CTD PMID:21161181 NCBI chr 1:58,561,965...58,625,492
Ensembl chr 1:58,561,965...58,625,482
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
multiple interactions
EXP
ISO
diethyl maleate results in decreased expression of ICAM1 mRNA
diethyl maleate inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; NFE2L2 protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]
CTD PMID:25270620 PMID:35724838 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression EXP diethyl maleate results in decreased expression of ID3 mRNA CTD PMID:25270620 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
JBrowse link
G Id4 inhibitor of DNA binding 4 decreases expression EXP diethyl maleate results in decreased expression of ID4 mRNA CTD PMID:25270620 NCBI chr13:48,414,592...48,419,504
Ensembl chr13:48,414,704...48,419,502
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO diethyl maleate results in decreased expression of IFIT3 mRNA CTD PMID:21161181 NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO diethyl maleate results in increased expression of IFRD1 mRNA CTD PMID:33545341 NCBI chr12:40,253,128...40,273,184
Ensembl chr12:40,251,566...40,298,503
JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon decreases expression EXP diethyl maleate results in decreased expression of IKBKE mRNA CTD PMID:25270620 NCBI chr 1:131,182,337...131,207,339
Ensembl chr 1:131,182,080...131,207,344
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma increases expression EXP diethyl maleate results in increased expression of IKBKG mRNA CTD PMID:25270620 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460
JBrowse link
G Il10 interleukin 10 increases secretion ISO diethyl maleate results in increased secretion of IL10 protein CTD PMID:31958493 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il18 interleukin 18 increases expression ISO diethyl maleate results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO diethyl maleate inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; diethyl maleate inhibits the reaction [IL1B protein affects the localization of RELA protein]; diethyl maleate inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; diethyl maleate inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein] CTD PMID:35724838 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1r1 interleukin 1 receptor, type I affects expression ISO diethyl maleate affects the expression of IL1R1 mRNA CTD PMID:34480604 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein CTD PMID:31958493 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Inhbb inhibin beta-B decreases expression EXP diethyl maleate results in decreased expression of INHBB mRNA CTD PMID:25270620 NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression ISO diethyl maleate results in decreased expression of INMT mRNA CTD PMID:21161181 NCBI chr 6:55,147,612...55,151,975
Ensembl chr 6:55,147,611...55,152,028
JBrowse link
G Ins2 insulin II multiple interactions ISO diethyl maleate inhibits the reaction [INS protein affects the localization of and results in increased phosphorylation of FOXO1 protein] CTD PMID:30261343 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Ints7 integrator complex subunit 7 decreases expression EXP diethyl maleate results in decreased expression of INTS7 mRNA CTD PMID:25270620 NCBI chr 1:191,307,652...191,355,802
Ensembl chr 1:191,307,748...191,355,800
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO diethyl maleate results in decreased expression of IRF7 mRNA CTD PMID:21161181 NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
JBrowse link
G Irf9 interferon regulatory factor 9 decreases expression ISO diethyl maleate results in decreased expression of IRF9 mRNA CTD PMID:21161181 NCBI chr14:55,841,442...55,847,487
Ensembl chr14:55,841,028...55,847,487
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 decreases expression ISO diethyl maleate results in decreased expression of IRGM mRNA CTD PMID:21161181 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510
JBrowse link
G Itgal integrin alpha L decreases expression ISO diethyl maleate results in decreased expression of ITGAL mRNA CTD PMID:21161181 NCBI chr 7:126,895,404...126,934,309
Ensembl chr 7:126,895,432...126,934,310
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression EXP diethyl maleate results in decreased expression of ITIH3 mRNA CTD PMID:25270620 NCBI chr14:30,630,529...30,645,748
Ensembl chr14:30,630,529...30,645,717
JBrowse link
G Itih4 inter alpha-trypsin inhibitor, heavy chain 4 decreases expression EXP diethyl maleate results in decreased expression of ITIH4 mRNA CTD PMID:25270620 NCBI chr14:30,608,433...30,623,943
Ensembl chr14:30,608,433...30,624,310
JBrowse link
G Jam3 junction adhesion molecule 3 decreases expression ISO diethyl maleate results in decreased expression of JAM3 mRNA CTD PMID:21161181 NCBI chr 9:27,008,680...27,066,739
Ensembl chr 9:27,008,680...27,066,717
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases phosphorylation
increases expression
EXP
ISO
pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]
diethyl maleate results in increased expression of JUN mRNA
pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of JUN protein modified form]
CTD PMID:10915739 PMID:12774022 PMID:30261343 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kcne3 potassium voltage-gated channel, Isk-related subfamily, gene 3 decreases expression EXP diethyl maleate results in decreased expression of KCNE3 mRNA CTD PMID:25270620 NCBI chr 7:99,825,714...99,834,076
Ensembl chr 7:99,825,709...99,834,076
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 increases expression ISO diethyl maleate results in increased expression of KEAP1 mRNA; diethyl maleate results in increased expression of KEAP1 protein CTD PMID:27358234 PMID:33545341 PMID:34480604 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Khdrbs3 KH domain containing, RNA binding, signal transduction associated 3 increases expression ISO diethyl maleate results in increased expression of KHDRBS3 mRNA CTD PMID:33545341 NCBI chr15:68,800,155...68,973,064
Ensembl chr15:68,800,269...68,973,060
JBrowse link
G Kifc1 kinesin family member C1 increases expression ISO diethyl maleate results in increased expression of KIFC1 mRNA CTD PMID:21161181 NCBI chr17:34,094,640...34,109,607
Ensembl chr17:34,094,633...34,109,635
JBrowse link
G Klf10 Kruppel-like transcription factor 10 decreases expression ISO
EXP
diethyl maleate results in decreased expression of KLF10 mRNA CTD PMID:21161181 PMID:25270620 NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950
JBrowse link
G Krt75 keratin 75 increases reduction EXP diethyl maleate results in increased reduction of KRT75 protein CTD PMID:19843705 NCBI chr15:101,471,778...101,482,339
Ensembl chr15:101,471,780...101,482,339
JBrowse link
G Lama1 laminin, alpha 1 decreases expression EXP diethyl maleate results in decreased expression of LAMA1 mRNA CTD PMID:25270620 NCBI chr17:68,004,129...68,129,640
Ensembl chr17:68,004,254...68,129,642
JBrowse link
G Lancl2 LanC (bacterial lantibiotic synthetase component C)-like 2 decreases expression EXP diethyl maleate results in decreased expression of LANCL2 mRNA CTD PMID:25270620 NCBI chr 6:57,679,440...57,716,434
Ensembl chr 6:57,679,525...57,716,424
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO diethyl maleate results in decreased expression of LDLR mRNA CTD PMID:21161181 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lepr leptin receptor decreases expression ISO diethyl maleate results in decreased expression of LEPR mRNA CTD PMID:21161181 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
JBrowse link
G Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein decreases expression ISO diethyl maleate results in decreased expression of LGALS3BP mRNA CTD PMID:21161181 NCBI chr11:118,283,573...118,292,787
Ensembl chr11:118,283,577...118,292,918
JBrowse link
G Lmnb1 lamin B1 increases expression ISO diethyl maleate results in increased expression of LMNB1 mRNA CTD PMID:21161181 NCBI chr18:56,840,885...56,886,496
Ensembl chr18:56,840,885...56,886,496
JBrowse link
G Lmo7 LIM domain only 7 decreases expression ISO diethyl maleate results in decreased expression of LMO7 mRNA CTD PMID:21161181 NCBI chr14:101,967,353...102,172,144
Ensembl chr14:101,967,393...102,172,146
JBrowse link
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 decreases expression ISO diethyl maleate results in decreased expression of LRIG3 mRNA CTD PMID:21161181 NCBI chr10:125,802,088...125,851,228
Ensembl chr10:125,802,037...125,851,228
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 increases expression ISO diethyl maleate results in increased expression of LRRN4 mRNA CTD PMID:21161181 NCBI chr 2:132,710,436...132,735,930
Ensembl chr 2:132,710,225...132,722,811
JBrowse link
G Lrtm2 leucine-rich repeats and transmembrane domains 2 decreases expression ISO diethyl maleate results in decreased expression of LRTM2 mRNA CTD PMID:21161181 NCBI chr 6:119,292,094...119,315,009
Ensembl chr 6:119,292,094...119,307,727
JBrowse link
G Ltc4s leukotriene C4 synthase decreases expression ISO diethyl maleate results in decreased expression of LTC4S mRNA CTD PMID:21161181 NCBI chr11:50,127,288...50,129,378
Ensembl chr11:50,127,288...50,129,443
JBrowse link
G Lum lumican decreases expression ISO diethyl maleate results in decreased expression of LUM mRNA CTD PMID:21161181 NCBI chr10:97,401,363...97,408,565
Ensembl chr10:97,400,990...97,408,565
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO diethyl maleate results in increased expression of MAFF mRNA CTD PMID:20491607 PMID:33545341 NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
JBrowse link
G Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) increases expression ISO diethyl maleate results in increased expression of MAFG mRNA CTD PMID:33545341 PMID:34480604 NCBI chr11:120,515,943...120,525,771
Ensembl chr11:120,515,943...120,524,426
JBrowse link
G Maoa monoamine oxidase A increases expression EXP diethyl maleate results in increased expression of MAOA mRNA CTD PMID:25270620 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057
JBrowse link
G Mapk1ip1l mitogen-activated protein kinase 1 interacting protein 1-like increases expression ISO diethyl maleate results in increased expression of MAPK1IP1L mRNA CTD PMID:33545341 NCBI chr14:47,535,731...47,560,663
Ensembl chr14:47,535,723...47,560,661
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression
multiple interactions
ISO diethyl maleate results in increased expression of MAPK8 protein modified form
pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of MAPK8 protein modified form]
CTD PMID:30261343 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases expression
multiple interactions
ISO diethyl maleate results in increased expression of MAPK9 protein modified form
pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of MAPK9 protein modified form]
CTD PMID:30261343 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Marveld1 MARVEL (membrane-associating) domain containing 1 decreases expression ISO diethyl maleate results in decreased expression of MARVELD1 mRNA CTD PMID:21161181 NCBI chr19:42,135,879...42,140,137
Ensembl chr19:42,135,839...42,140,142
JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 increases expression ISO diethyl maleate results in increased expression of MBOAT7 mRNA CTD PMID:33545341 NCBI chr 7:3,680,788...3,696,188
Ensembl chr 7:3,680,788...3,696,522
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor increases expression ISO diethyl maleate results in increased expression of MCM10 mRNA CTD PMID:21161181 NCBI chr 2:4,995,535...5,017,602
Ensembl chr 2:4,994,525...5,017,602
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression ISO diethyl maleate results in increased expression of MCM4 mRNA CTD PMID:21161181 NCBI chr16:15,441,761...15,455,264
Ensembl chr16:15,441,761...15,455,264
JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic increases expression EXP diethyl maleate results in increased expression of ME1 mRNA CTD PMID:25270620 NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006
JBrowse link
G Mfap4 microfibrillar-associated protein 4 decreases expression ISO diethyl maleate results in decreased expression of MFAP4 mRNA CTD PMID:21161181 NCBI chr11:61,376,257...61,379,536
Ensembl chr11:61,376,257...61,379,726
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO diethyl maleate results in decreased activity of MGMT protein CTD PMID:16950796 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 increases expression ISO diethyl maleate results in increased expression of MKI67 mRNA CTD PMID:21161181 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 decreases expression ISO diethyl maleate results in decreased expression of MKNK2 mRNA CTD PMID:21161181 NCBI chr10:80,501,152...80,512,264
Ensembl chr10:80,501,161...80,513,946
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression EXP diethyl maleate results in increased expression of MMP12 mRNA CTD PMID:10216232 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) increases expression ISO diethyl maleate results in increased expression of MMP1 mRNA CTD PMID:33545341 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO diethyl maleate results in decreased expression of MMP2 mRNA CTD PMID:21161181 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO diethyl maleate results in increased expression of MMP3 mRNA CTD PMID:33545341 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mpzl1 myelin protein zero-like 1 decreases expression ISO diethyl maleate results in decreased expression of MPZL1 mRNA CTD PMID:34480604 NCBI chr 1:165,419,745...165,462,144
Ensembl chr 1:165,419,809...165,462,107
JBrowse link
G Msn moesin increases reduction EXP diethyl maleate results in increased reduction of MSN protein CTD PMID:19843705 NCBI chr  X:95,139,651...95,212,159
Ensembl chr  X:95,139,648...95,212,158
JBrowse link
G Mt2 metallothionein 2 increases expression ISO diethyl maleate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Mx1 MX dynamin-like GTPase 1 decreases expression ISO diethyl maleate results in decreased expression of MX1 mRNA CTD PMID:21161181 NCBI chr16:97,248,235...97,264,106
Ensembl chr16:97,248,235...97,264,107
JBrowse link
G Mybl2 myeloblastosis oncogene-like 2 increases expression ISO diethyl maleate results in increased expression of MYBL2 mRNA CTD PMID:21161181 NCBI chr 2:162,896,246...162,926,608
Ensembl chr 2:162,896,607...162,926,608
JBrowse link
G Mycn v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived decreases expression EXP diethyl maleate results in decreased expression of MYCN mRNA CTD PMID:25270620 NCBI chr12:12,986,094...12,991,837
Ensembl chr12:12,986,094...12,991,915
JBrowse link
G Nat8 N-acetyltransferase 8 (GCN5-related) decreases expression ISO diethyl maleate results in decreased expression of NAT8 mRNA CTD PMID:21161181 NCBI chr 6:85,807,369...85,813,839
Ensembl chr 6:85,807,370...85,809,064
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression ISO diethyl maleate results in increased expression of NCAPH mRNA CTD PMID:21161181 NCBI chr 2:126,945,729...126,975,857
Ensembl chr 2:126,945,729...126,975,874
JBrowse link
G Ndrg1 N-myc downstream regulated gene 1 increases expression ISO diethyl maleate results in increased expression of NDRG1 mRNA CTD PMID:33545341 NCBI chr15:66,801,167...66,841,490
Ensembl chr15:66,801,167...66,841,489
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization
multiple interactions
decreases response to substance
increases expression
increases activity
EXP
ISO
diethyl maleate affects the localization of NFE2L2 protein
NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]
NFE2L2 results in decreased susceptibility to diethyl maleate
diethyl maleate results in increased expression of NFE2L2 protein
[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein; diethyl maleate binds to and results in increased activity of NFE2L2 protein; diethyl maleate promotes the reaction [NFE2L2 protein binds to SMPD1 promoter]; diethyl maleate results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SMPD1 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; NFE2L2 protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]; RELA protein inhibits the reaction [diethyl maleate results in increased expression of NFE2L2 protein]; RELA protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]; TNFAIP3 protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]
diethyl maleate results in increased activity of NFE2L2 protein
CTD PMID:12235164 PMID:20806931 PMID:21465251 PMID:22003191 PMID:25762726 More... NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP
ISO
diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]
diethyl maleate inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; diethyl maleate inhibits the reaction [TNF protein affects the localization of NFKBIA protein]
CTD PMID:12774022 PMID:35724838 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 decreases expression ISO diethyl maleate results in decreased expression of NHERF1 mRNA CTD PMID:21161181 NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP
ISO
diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
Acetylcysteine inhibits the reaction [diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate]
CTD PMID:7532384 PMID:9918918 PMID:12774022 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Notch1 notch 1 increases expression ISO diethyl maleate results in increased expression of NOTCH1 mRNA CTD PMID:33545341 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO
EXP
diethyl maleate results in increased expression of NQO1 mRNA CTD PMID:20491607 PMID:25270620 PMID:33545341 PMID:34480604 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO diethyl maleate results in decreased expression of NR0B2 mRNA CTD PMID:21161181 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO diethyl maleate results in decreased expression of NR1D1 mRNA CTD PMID:21161181 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO diethyl maleate results in decreased expression of NREP mRNA CTD PMID:21161181 NCBI chr18:33,570,072...33,597,444
Ensembl chr18:33,570,072...33,597,082
JBrowse link
G Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor decreases expression EXP diethyl maleate results in decreased expression of NSMF mRNA CTD PMID:25270620 NCBI chr 2:24,944,370...24,952,893
Ensembl chr 2:24,944,367...24,952,893
JBrowse link
G Ntf3 neurotrophin 3 decreases expression ISO diethyl maleate results in decreased expression of NTF3 mRNA CTD PMID:21161181 NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873
JBrowse link
G Nup153 nucleoporin 153 multiple interactions
affects localization
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; diethyl maleate results in increased phosphorylation of and results in increased O-linked glycosylation of NUP153 protein CTD PMID:20041180 NCBI chr13:46,833,369...46,890,682
Ensembl chr13:46,833,381...46,881,416
JBrowse link
G Nup88 nucleoporin 88 multiple interactions
affects localization
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] affects the reaction [diethyl maleate affects the localization of NUP88 protein]; diethyl maleate results in increased phosphorylation of and results in increased glycosylation of NUP88 protein CTD PMID:20041180 NCBI chr11:70,833,884...70,860,799
Ensembl chr11:70,833,884...70,860,799
JBrowse link
G Oaf out at first homolog decreases expression ISO diethyl maleate results in decreased expression of OAF mRNA CTD PMID:21161181 NCBI chr 9:43,132,575...43,151,113
Ensembl chr 9:43,132,532...43,151,208
JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 multiple interactions EXP [diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of OGG1 mRNA CTD PMID:22564015 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029
JBrowse link
G Orc1 origin recognition complex, subunit 1 increases expression ISO diethyl maleate results in increased expression of ORC1 mRNA CTD PMID:21161181 NCBI chr 4:108,436,651...108,472,030
Ensembl chr 4:108,436,620...108,472,030
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 increases expression ISO diethyl maleate results in increased expression of OSGIN1 mRNA CTD PMID:33545341 NCBI chr 8:120,160,874...120,172,996
Ensembl chr 8:120,160,863...120,172,995
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 decreases expression ISO diethyl maleate results in decreased expression of P2RX7 mRNA CTD PMID:21161181 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO diethyl maleate results in increased cleavage of PARP1 protein CTD PMID:21105742 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 decreases expression ISO diethyl maleate results in decreased expression of PBLD protein CTD PMID:21161181 NCBI chr10:62,896,404...62,913,743
Ensembl chr10:62,895,941...62,913,741
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO diethyl maleate results in decreased expression of PCNA mRNA CTD PMID:11875189 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pdlim2 PDZ and LIM domain 2 decreases expression ISO diethyl maleate results in decreased expression of PDLIM2 mRNA CTD PMID:21161181 NCBI chr14:70,401,667...70,415,140
Ensembl chr14:70,401,667...70,415,130
JBrowse link
G Pdrg1 p53 and DNA damage regulated 1 increases expression EXP diethyl maleate results in increased expression of PDRG1 mRNA CTD PMID:25270620 NCBI chr 2:152,850,810...152,857,939
Ensembl chr 2:152,850,810...152,857,347
JBrowse link
G Per2 period circadian clock 2 decreases expression ISO diethyl maleate results in decreased expression of PER2 mRNA CTD PMID:21161181 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046
JBrowse link
G Per3 period circadian clock 3 decreases expression ISO diethyl maleate results in decreased expression of PER3 mRNA CTD PMID:21161181 NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122
JBrowse link
G Pgd phosphogluconate dehydrogenase increases activity ISO diethyl maleate results in increased activity of PGD protein CTD PMID:3099627 NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 increases expression EXP diethyl maleate results in increased expression of PGRMC1 mRNA CTD PMID:25270620 NCBI chr  X:35,861,846...35,869,732
Ensembl chr  X:35,861,859...35,869,732
JBrowse link
G Pir pirin increases expression EXP diethyl maleate results in increased expression of PIR mRNA CTD PMID:25270620 NCBI chr  X:163,052,427...163,156,009
Ensembl chr  X:163,052,367...163,156,007
JBrowse link
G Pklr pyruvate kinase liver and red blood cell decreases expression ISO diethyl maleate results in decreased expression of PKLR mRNA CTD PMID:21161181 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091
JBrowse link
G Plat plasminogen activator, tissue increases expression
decreases expression
ISO
EXP
diethyl maleate results in increased expression of PLAT mRNA
diethyl maleate results in decreased expression of PLAT mRNA
CTD PMID:21161181 PMID:25270620 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plek pleckstrin decreases expression ISO diethyl maleate results in decreased expression of PLEK mRNA CTD PMID:21161181 NCBI chr11:16,921,206...16,958,718
Ensembl chr11:16,921,206...17,002,381
JBrowse link
G Plekhm1 pleckstrin homology domain containing, family M (with RUN domain) member 1 increases expression ISO diethyl maleate results in increased expression of PLEKHM1 mRNA CTD PMID:33545341 NCBI chr11:103,255,101...103,303,531
Ensembl chr11:103,255,101...103,303,513
JBrowse link
G Plin2 perilipin 2 increases expression ISO diethyl maleate results in increased expression of PLIN2 mRNA CTD PMID:33545341 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
JBrowse link
G Plk1 polo like kinase 1 increases expression ISO diethyl maleate results in increased expression of PLK1 mRNA CTD PMID:33545341 NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096
JBrowse link
G Plk3 polo like kinase 3 increases expression ISO diethyl maleate results in increased expression of PLK3 mRNA CTD PMID:33545341 NCBI chr 4:116,985,852...116,991,244
Ensembl chr 4:116,985,852...116,991,160
JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 increases expression ISO diethyl maleate results in increased expression of POU5F1 mRNA CTD PMID:33545341 NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases activity
ISO diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol inhibits the reaction [diethyl maleate results in decreased activity of PPARA protein]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate results in decreased activity of PPARA protein] CTD PMID:17134953 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta decreases expression ISO diethyl maleate results in decreased expression of PPARGC1B mRNA CTD PMID:21161181 NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502
JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression ISO diethyl maleate results in decreased expression of PPP1R3B mRNA CTD PMID:21161181 NCBI chr 8:35,842,847...35,855,293
Ensembl chr 8:35,842,893...35,855,293
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression ISO diethyl maleate results in decreased expression of PPP1R3C mRNA CTD PMID:21161181 NCBI chr19:36,709,131...36,714,004
Ensembl chr19:36,709,131...36,714,053
JBrowse link
G Prdm14 PR domain containing 14 decreases expression EXP diethyl maleate results in decreased expression of PRDM14 mRNA CTD PMID:25270620 NCBI chr 1:13,183,649...13,197,467
Ensembl chr 1:13,183,681...13,197,387
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression EXP
ISO
diethyl maleate results in increased expression of PRDX1 mRNA CTD PMID:9506838 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
JBrowse link
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit decreases expression EXP diethyl maleate results in decreased expression of PRKAB1 mRNA CTD PMID:25270620 NCBI chr 5:116,151,654...116,162,449
Ensembl chr 5:116,151,645...116,162,567
JBrowse link
G Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit increases expression ISO diethyl maleate results in increased expression of PRKAG2 mRNA CTD PMID:33545341 NCBI chr 5:25,067,733...25,311,576
Ensembl chr 5:25,067,742...25,305,640
JBrowse link
G Prkcb protein kinase C, beta affects expression ISO diethyl maleate affects the expression of PRKCB protein CTD PMID:31958493 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625
JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCD protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCD protein CTD PMID:11118818 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCE protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCE protein CTD PMID:11118818 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347
JBrowse link
G Prss8 serine protease 8 (prostasin) decreases expression ISO diethyl maleate results in decreased expression of PRSS8 mRNA CTD PMID:21161181 NCBI chr 7:127,524,889...127,529,266
Ensembl chr 7:127,524,888...127,529,276
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression EXP diethyl maleate results in increased expression of PTGR1 mRNA CTD PMID:25270620 NCBI chr 4:58,965,590...58,987,131
Ensembl chr 4:58,965,439...58,987,119
JBrowse link
G Ptpn14 protein tyrosine phosphatase, non-receptor type 14 increases expression EXP diethyl maleate results in increased expression of PTPN14 mRNA CTD PMID:25270620 NCBI chr 1:189,460,417...189,608,892
Ensembl chr 1:189,460,465...189,608,892
JBrowse link
G Pus1 pseudouridine synthase 1 decreases expression EXP diethyl maleate results in decreased expression of PUS1 mRNA CTD PMID:25270620 NCBI chr 5:110,921,533...110,928,523
Ensembl chr 5:110,921,533...110,928,525
JBrowse link
G Pxn paxillin increases expression ISO diethyl maleate results in increased expression of PXN mRNA CTD PMID:33545341 NCBI chr 5:115,630,035...115,694,046
Ensembl chr 5:115,644,735...115,694,046
JBrowse link
G Rab27a RAB27A, member RAS oncogene family decreases expression ISO diethyl maleate results in decreased expression of RAB27A mRNA CTD PMID:21161181 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]]; diethyl maleate inhibits the reaction [IL1B protein affects the localization of RELA protein]; diethyl maleate inhibits the reaction [TNF protein affects the localization of RELA protein]; RELA protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]]; RELA protein inhibits the reaction [diethyl maleate results in increased expression of NFE2L2 protein]; RELA protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]; RELA protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein] CTD PMID:20116392 PMID:35724838 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rho rhodopsin increases expression ISO diethyl maleate results in increased expression of RHO mRNA CTD PMID:33545341 NCBI chr 6:115,903,741...115,916,999
Ensembl chr 6:115,908,709...115,916,997
JBrowse link
G Rnf114 ring finger protein 114 decreases expression EXP diethyl maleate results in decreased expression of RNF114 mRNA CTD PMID:25270620 NCBI chr 2:167,334,565...167,358,093
Ensembl chr 2:167,334,565...167,358,093
JBrowse link
G Rnf14 ring finger protein 14 increases expression EXP diethyl maleate results in increased expression of RNF14 mRNA CTD PMID:25270620 NCBI chr18:38,410,513...38,450,905
Ensembl chr18:38,417,590...38,450,902
JBrowse link
G Rrm2 ribonucleotide reductase M2 increases expression ISO diethyl maleate results in increased expression of RRM2 mRNA CTD PMID:21161181 PMID:33545341 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of RSAD2 mRNA CTD PMID:21161181 NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) decreases expression ISO diethyl maleate results in decreased expression of S100A9 mRNA CTD PMID:21161181 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
JBrowse link
G Sash3 SAM and SH3 domain containing 3 decreases expression ISO diethyl maleate results in decreased expression of SASH3 mRNA CTD PMID:21161181 NCBI chr  X:47,235,313...47,250,442
Ensembl chr  X:47,235,313...47,250,442
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO diethyl maleate results in decreased expression of SCARB1 mRNA CTD PMID:34480604 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 decreases expression ISO diethyl maleate results in decreased expression of SCD1 mRNA CTD PMID:21161181 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Sds serine dehydratase decreases expression ISO diethyl maleate results in decreased expression of SDS mRNA CTD PMID:21161181 NCBI chr 5:120,614,612...120,621,997
Ensembl chr 5:120,614,591...120,621,997
JBrowse link
G Selenop selenoprotein P decreases expression ISO diethyl maleate results in decreased expression of SELENOP mRNA CTD PMID:30261343 NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990
JBrowse link
G Serpinb6b serine (or cysteine) peptidase inhibitor, clade B, member 6b decreases expression EXP diethyl maleate results in decreased expression of SERPINB6B mRNA CTD PMID:25270620 NCBI chr13:33,140,797...33,163,050
Ensembl chr13:33,149,192...33,163,050
JBrowse link
G Serpind1 serine (or cysteine) peptidase inhibitor, clade D, member 1 decreases expression EXP diethyl maleate results in decreased expression of SERPIND1 mRNA CTD PMID:25270620 NCBI chr16:17,149,235...17,161,438
Ensembl chr16:17,149,235...17,161,439
JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO diethyl maleate results in increased expression of SERTAD1 mRNA CTD PMID:33545341 NCBI chr 7:27,186,378...27,189,741
Ensembl chr 7:27,186,335...27,189,741
JBrowse link
G Sez6 seizure related gene 6 decreases expression ISO diethyl maleate results in decreased expression of SEZ6 mRNA CTD PMID:21161181 NCBI chr11:77,821,403...77,869,874
Ensembl chr11:77,821,626...77,869,874
JBrowse link
G Sfxn1 sideroflexin 1 decreases expression EXP diethyl maleate results in decreased expression of SFXN1 mRNA CTD PMID:25270620 NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 (BTK-associated) increases expression
affects expression
ISO diethyl maleate results in increased expression of SH3BP5 mRNA
diethyl maleate affects the expression of SH3BP5 mRNA
CTD PMID:33545341 PMID:34480604 NCBI chr14:31,094,571...31,158,056
Ensembl chr14:31,081,837...31,158,035
JBrowse link
G Six4 sine oculis-related homeobox 4 increases expression EXP diethyl maleate results in increased expression of SIX4 mRNA CTD PMID:25270620 NCBI chr12:73,146,383...73,160,201
Ensembl chr12:73,146,383...73,160,230
JBrowse link
G Slc16a6 solute carrier family 16 (monocarboxylic acid transporters), member 6 decreases expression EXP diethyl maleate results in decreased expression of SLC16A6 mRNA CTD PMID:25270620 NCBI chr11:109,341,681...109,366,428
Ensembl chr11:109,341,681...109,364,424
JBrowse link
G Slc1a4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 increases expression EXP diethyl maleate results in increased expression of SLC1A4 mRNA CTD PMID:25270620 NCBI chr11:20,252,180...20,282,713
Ensembl chr11:20,252,180...20,282,713
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 decreases expression ISO diethyl maleate results in decreased expression of SLC2A2 mRNA CTD PMID:21161181 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Slc2a5 solute carrier family 2 (facilitated glucose transporter), member 5 decreases expression ISO diethyl maleate results in decreased expression of SLC2A5 mRNA CTD PMID:21161181 NCBI chr 4:150,203,801...150,228,625
Ensembl chr 4:150,203,740...150,228,626
JBrowse link
G Slc39a14 solute carrier family 39 (zinc transporter), member 14 decreases expression EXP diethyl maleate results in decreased expression of SLC39A14 mRNA CTD PMID:25270620 NCBI chr14:70,540,916...70,588,873
Ensembl chr14:70,540,918...70,588,874
JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 increases expression ISO diethyl maleate results in increased expression of SLC3A2 mRNA CTD PMID:33545341 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733
JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 multiple interactions ISO diethyl maleate inhibits the reaction [Lipopolysaccharides results in decreased expression of SLC40A1 mRNA] CTD PMID:21303654 NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683
JBrowse link
G Slc44a4 solute carrier family 44, member 4 decreases expression ISO diethyl maleate results in decreased expression of SLC44A4 mRNA CTD PMID:21161181 NCBI chr17:35,133,200...35,149,412
Ensembl chr17:35,133,442...35,149,412
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 multiple interactions
increases expression
EXP
ISO
NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA] CTD PMID:12235164 PMID:33545341 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 decreases expression ISO diethyl maleate results in decreased expression of SLCO2A1 mRNA CTD PMID:21161181 NCBI chr 9:102,885,686...102,973,201
Ensembl chr 9:102,865,911...102,973,201
JBrowse link
G Slfn3 schlafen 3 decreases expression ISO diethyl maleate results in decreased expression of SLFN3 mRNA CTD PMID:21161181 NCBI chr11:83,082,156...83,105,980
Ensembl chr11:83,082,156...83,105,980
JBrowse link
G Smc4 structural maintenance of chromosomes 4 increases expression ISO diethyl maleate results in increased expression of SMC4 mRNA CTD PMID:21161181 NCBI chr 3:68,912,071...68,941,956
Ensembl chr 3:68,912,071...68,941,956
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal increases expression
increases activity
multiple interactions
ISO diethyl maleate results in increased expression of SMPD1 mRNA
diethyl maleate results in increased activity of SMPD1 protein
Dactinomycin inhibits the reaction [diethyl maleate results in increased expression of SMPD1 mRNA]; diethyl maleate promotes the reaction [NFE2L2 protein binds to SMPD1 promoter]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SMPD1 mRNA]
CTD PMID:25762726 NCBI chr 7:105,203,567...105,207,596
Ensembl chr 7:105,203,567...105,207,596
JBrowse link
G Smtn smoothelin increases expression ISO diethyl maleate results in increased expression of SMTN mRNA CTD PMID:21161181 NCBI chr11:3,467,522...3,489,337
Ensembl chr11:3,467,523...3,490,612
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression EXP diethyl maleate results in decreased expression of SOCS3 mRNA CTD PMID:25270620 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sorl1 sortilin-related receptor, LDLR class A repeats-containing decreases expression ISO diethyl maleate results in decreased expression of SORL1 mRNA CTD PMID:21161181 NCBI chr 9:41,876,005...42,035,593
Ensembl chr 9:41,876,016...42,035,593
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 increases expression ISO diethyl maleate results in increased expression of SOX9 mRNA CTD PMID:21161181 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Sp5 trans-acting transcription factor 5 decreases expression EXP diethyl maleate results in decreased expression of SP5 mRNA CTD PMID:25270620 NCBI chr 2:70,305,267...70,308,070
Ensembl chr 2:70,305,267...70,308,073
JBrowse link
G Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) increases expression ISO diethyl maleate results in increased expression of SPC25 mRNA CTD PMID:21161181 NCBI chr 2:69,009,753...69,036,583
Ensembl chr 2:69,024,239...69,036,538
JBrowse link
G Spta1 spectrin alpha, erythrocytic 1 increases expression EXP diethyl maleate results in increased expression of SPTA1 mRNA CTD PMID:25270620 NCBI chr 1:174,000,305...174,076,015
Ensembl chr 1:174,000,342...174,076,016
JBrowse link
G Sptan1 spectrin alpha, non-erythrocytic 1 increases cleavage ISO diethyl maleate results in increased cleavage of SPTAN1 protein CTD PMID:21105742 NCBI chr 2:29,855,572...29,921,463
Ensembl chr 2:29,855,572...29,921,463
JBrowse link
G Sptbn4 spectrin beta, non-erythrocytic 4 increases expression EXP diethyl maleate results in increased expression of SPTBN4 mRNA CTD PMID:25270620 NCBI chr 7:27,055,808...27,147,128
Ensembl chr 7:27,055,808...27,147,111
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 increases expression ISO diethyl maleate results in increased expression of SPTLC1 mRNA CTD PMID:33545341 NCBI chr13:53,486,784...53,531,401
Ensembl chr13:53,486,784...53,531,433
JBrowse link
G Sqstm1 sequestosome 1 increases expression EXP
ISO
diethyl maleate results in increased expression of SQSTM1 mRNA CTD PMID:25270620 PMID:33545341 PMID:34480604 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO diethyl maleate results in decreased expression of SREBF1 mRNA CTD PMID:21161181 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) multiple interactions
increases expression
decreases expression
EXP
ISO
[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]
diethyl maleate results in increased expression of SRXN1 mRNA; diethyl maleate results in increased expression of SRXN1 protein
[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; NFE2L2 protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]; RELA protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; RELA protein promotes the reaction [diethyl maleate results in increased expression of SRXN1 protein]; TNFAIP3 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
diethyl maleate results in decreased expression of SRXN1 mRNA
CTD PMID:22003191 PMID:25270620 PMID:27358234 PMID:27982581 PMID:33545341 More... NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO diethyl maleate results in decreased expression of STAT1 mRNA CTD PMID:21161181 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
JBrowse link
G Steap4 STEAP family member 4 decreases expression EXP diethyl maleate results in decreased expression of STEAP4 mRNA CTD PMID:25270620 NCBI chr 5:8,010,472...8,032,213
Ensembl chr 5:8,010,457...8,032,213
JBrowse link
G Sulf2 sulfatase 2 decreases expression ISO diethyl maleate results in decreased expression of SULF2 mRNA CTD PMID:21161181 NCBI chr 2:165,915,819...165,997,603
Ensembl chr 2:165,915,009...165,997,583
JBrowse link
G Tagln transgelin decreases expression ISO diethyl maleate results in decreased expression of TAGLN mRNA CTD PMID:21161181 NCBI chr 9:45,840,926...45,847,356
Ensembl chr 9:45,840,917...45,847,356
JBrowse link
G Tatdn2 TatD DNase domain containing 2 increases expression ISO diethyl maleate results in increased expression of TATDN2 mRNA CTD PMID:33545341 NCBI chr 6:113,674,090...113,688,030
Ensembl chr 6:113,674,011...113,688,030
JBrowse link
G Tbcel tubulin folding cofactor E-like increases expression EXP diethyl maleate results in increased expression of TBCEL mRNA CTD PMID:25270620 NCBI chr 9:42,323,612...42,383,534
Ensembl chr 9:42,323,612...42,419,105
JBrowse link
G Tent4a terminal nucleotidyltransferase 4A increases expression ISO diethyl maleate results in increased expression of TENT4A mRNA CTD PMID:33545341 NCBI chr13:69,646,071...69,682,710
Ensembl chr13:69,646,078...69,682,736
JBrowse link
G Tent5a terminal nucleotidyltransferase 5A decreases expression ISO diethyl maleate results in decreased expression of TENT5A mRNA CTD PMID:21161181 NCBI chr 9:85,202,492...85,209,203
Ensembl chr 9:85,202,492...85,209,401
JBrowse link
G Tesmin testis expressed metallothionein like affects localization EXP diethyl maleate affects the localization of TESMIN protein CTD PMID:12606435 NCBI chr19:3,438,857...3,457,823
Ensembl chr19:3,438,857...3,457,823
JBrowse link
G Tfeb transcription factor EB decreases expression EXP diethyl maleate results in decreased expression of TFEB mRNA CTD PMID:25270620 NCBI chr17:48,047,962...48,103,341
Ensembl chr17:48,047,955...48,103,344
JBrowse link
G Tgm2 transglutaminase 2, C polypeptide increases expression ISO diethyl maleate results in increased expression of TGM2 mRNA CTD PMID:21161181 NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO diethyl maleate results in increased expression of THBS1 mRNA CTD PMID:21161181 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO diethyl maleate results in decreased expression of THRSP mRNA CTD PMID:21161181 NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937
JBrowse link
G Tm4sf1 transmembrane 4 superfamily member 1 increases expression ISO diethyl maleate results in increased expression of TM4SF1 mRNA CTD PMID:21161181 NCBI chr 3:57,193,038...57,295,150
Ensembl chr 3:57,193,032...57,209,409
Ensembl chr 3:57,193,032...57,209,409
JBrowse link
G Tmem209 transmembrane protein 209 increases expression EXP diethyl maleate results in increased expression of TMEM209 mRNA CTD PMID:25270620 NCBI chr 6:30,480,806...30,509,786
Ensembl chr 6:30,479,052...30,509,782
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; [diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein; [diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein; diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]]; diethyl maleate inhibits the reaction [TNF protein affects the localization of NFKBIA protein]; diethyl maleate inhibits the reaction [TNF protein affects the localization of RELA protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; NFE2L2 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; NFE2L2 protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]]; RELA protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]; TNFAIP3 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; TNFAIP3 protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein]
diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]
diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate]
CTD PMID:7476933 PMID:7532384 PMID:12774022 PMID:20116392 PMID:31958493 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 multiple interactions ISO diethyl maleate inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; RELA protein inhibits the reaction [diethyl maleate inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]]; TNFAIP3 protein inhibits the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of SRXN1 protein]; TNFAIP3 protein promotes the reaction [[diethyl maleate co-treated with TNF protein] results in decreased expression of NFE2L2 protein] CTD PMID:35724838 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
JBrowse link
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) decreases expression ISO diethyl maleate results in decreased expression of TNFRSF14 mRNA CTD PMID:21161181 NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020
JBrowse link
G Tpm2 tropomyosin 2, beta decreases expression ISO diethyl maleate results in decreased expression of TPM2 mRNA CTD PMID:21161181 NCBI chr 4:43,513,726...43,523,583
Ensembl chr 4:43,514,711...43,523,765
JBrowse link
G Trap1 TNF receptor-associated protein 1 multiple interactions
decreases response to substance
ISO diethyl maleate inhibits the reaction [Cisplatin results in decreased expression of TRAP1 protein]
TRAP1 protein results in decreased susceptibility to diethyl maleate
CTD PMID:17853063 NCBI chr16:3,857,835...3,895,704
Ensembl chr16:3,857,835...3,895,691
JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 decreases expression EXP diethyl maleate results in decreased expression of TRDMT1 mRNA CTD PMID:25270620 NCBI chr 2:13,509,690...13,549,475
Ensembl chr 2:13,513,825...13,549,479
JBrowse link
G Trf transferrin decreases expression ISO diethyl maleate results in decreased expression of TF protein CTD PMID:21161181 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO diethyl maleate results in increased expression of TRIB1 mRNA CTD PMID:33545341 NCBI chr15:59,520,503...59,528,948
Ensembl chr15:59,520,199...59,528,948
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO diethyl maleate results in increased expression of TRIB3 mRNA CTD PMID:33545341 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
JBrowse link
G Trim6 tripartite motif-containing 6 decreases expression ISO diethyl maleate results in decreased expression of TRIM6 mRNA CTD PMID:21161181 NCBI chr 7:103,868,002...103,884,359
Ensembl chr 7:103,868,000...103,884,359
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 increases expression ISO diethyl maleate results in increased expression of TRIP13 mRNA CTD PMID:21161181 NCBI chr13:74,060,577...74,085,855
Ensembl chr13:74,059,466...74,085,903
JBrowse link
G Trp53 transformation related protein 53 multiple interactions EXP
ISO
TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]
TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
CTD PMID:22003191 PMID:27982581 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression ISO diethyl maleate results in decreased expression of TSC22D1 mRNA CTD PMID:21161181 NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205
JBrowse link
G Tspan8 tetraspanin 8 decreases expression ISO diethyl maleate results in decreased expression of TSPAN8 mRNA CTD PMID:21161181 NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798
JBrowse link
G Tstd1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 decreases expression EXP diethyl maleate results in decreased expression of TSTD1 mRNA CTD PMID:25270620 NCBI chr 1:171,246,601...171,247,920
Ensembl chr 1:171,246,440...171,247,920
JBrowse link
G Txn1 thioredoxin 1 decreases activity ISO diethyl maleate results in decreased activity of TXN protein CTD PMID:15388247 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO diethyl maleate results in increased expression of TXNIP mRNA CTD PMID:21161181 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO diethyl maleate results in increased expression of TXNRD1 mRNA CTD PMID:15521073 PMID:33545341 PMID:34480604 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
JBrowse link
G Ubd ubiquitin D decreases expression ISO diethyl maleate results in decreased expression of UBD mRNA CTD PMID:21161181 NCBI chr17:37,504,783...37,506,992
Ensembl chr17:37,504,783...37,506,986
JBrowse link
G Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35 increases expression EXP diethyl maleate results in increased expression of UGT2B35 mRNA CTD PMID:25270620 NCBI chr 5:87,148,719...87,161,133
Ensembl chr 5:87,148,719...87,161,134
JBrowse link
G Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 increases expression ISO diethyl maleate results in increased expression of UHRF1 mRNA CTD PMID:21161181 NCBI chr17:56,610,405...56,630,486
Ensembl chr17:56,610,321...56,630,486
JBrowse link
G Usp18 ubiquitin specific peptidase 18 decreases expression ISO diethyl maleate results in decreased expression of USP18 mRNA CTD PMID:21161181 NCBI chr 6:121,222,865...121,247,876
Ensembl chr 6:121,222,865...121,247,876
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression ISO diethyl maleate results in decreased expression of USP2 mRNA CTD PMID:21161181 NCBI chr 9:43,978,318...44,006,924
Ensembl chr 9:43,978,318...44,006,924
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO diethyl maleate results in increased expression of VEGFA mRNA CTD PMID:33545341 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Wdr31 WD repeat domain 31 decreases expression EXP diethyl maleate results in decreased expression of WDR31 mRNA CTD PMID:25270620 NCBI chr 4:62,366,890...62,389,236
Ensembl chr 4:62,366,890...62,389,133
JBrowse link
G Wdr6 WD repeat domain 6 decreases expression ISO diethyl maleate results in decreased expression of WDR6 mRNA CTD PMID:21161181 NCBI chr 9:108,449,510...108,455,862
Ensembl chr 9:108,449,510...108,455,938
JBrowse link
G Ypel5 yippee like 5 increases expression EXP diethyl maleate results in increased expression of YPEL5 mRNA CTD PMID:25270620 NCBI chr17:73,143,623...73,157,439
Ensembl chr17:73,143,448...73,158,190
JBrowse link
G Zfand2a zinc finger, AN1-type domain 2A increases expression ISO diethyl maleate results in increased expression of ZFAND2A mRNA CTD PMID:33545341 PMID:34480604 NCBI chr 5:139,456,971...139,470,246
Ensembl chr 5:139,456,966...139,470,304
JBrowse link
G Zfp36 zinc finger protein 36 increases expression ISO diethyl maleate results in increased expression of ZFP36 protein CTD PMID:21969073 NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678
JBrowse link
G Zfp367 zinc finger protein 367 increases expression ISO diethyl maleate results in increased expression of ZNF367 mRNA CTD PMID:21161181 NCBI chr13:64,280,836...64,301,013
Ensembl chr13:64,280,832...64,301,016
JBrowse link
G Zfp37 zinc finger protein 37 decreases expression ISO diethyl maleate results in decreased expression of ZFP37 mRNA CTD PMID:21161181 NCBI chr 4:62,107,777...62,126,685
Ensembl chr 4:62,107,777...62,149,284
JBrowse link
G Zfp493 zinc finger protein 493 decreases reduction EXP diethyl maleate results in decreased reduction of ZFP493 protein CTD PMID:19843705 NCBI chr13:67,927,812...67,937,201
Ensembl chr13:67,927,812...67,940,631
JBrowse link
G Znrd2 zinc ribbon domain containing 2 decreases expression EXP diethyl maleate results in decreased expression of ZNRD2 mRNA CTD PMID:25270620 NCBI chr19:5,780,334...5,781,760
Ensembl chr19:5,780,331...5,781,760
Ensembl chr19:5,780,331...5,781,760
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22163
      biological role 22162
        glutathione depleting agent 400
          diethyl maleate 400
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22170
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21906
                        carbon atom 21832
                          organic molecular entity 21832
                            organic group 20276
                              organic divalent group 20158
                                organodiyl group 20158
                                  carbonyl group 20151
                                    carbonyl compound 20151
                                      dicarboxylic acids and O-substituted derivatives 10887
                                        dicarboxylic acid 10881
                                          C4-dicarboxylic acid 1324
                                            butenedioic acid 618
                                              maleic acid 583
                                                maleate ester 400
                                                  diethyl maleate 400
paths to the root