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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:apoptosis inhibitor
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Accession:CHEBI:68494 term browser browse the term
Definition:Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
Synonyms:related_synonym: Type I cell-death inhibitor;   Type I cell-death inhibitors;   Type I programmed cell-death inhibitor;   Type I programmed cell-death inhibitors;   apoptosis inhibitors



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bis(2-ethylhexyl) phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1I3 nuclear receptor subfamily 1 group I member 3 increases activity EXP Diethylhexyl Phthalate results in increased activity of NR1I3 protein CTD PMID:27732639 NCBI chr38:21,252,874...21,257,951
Ensembl chr38:21,253,089...21,258,827
JBrowse link
propranolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 multiple interactions EXP [Propranolol binds to and results in decreased activity of ADRB2 protein] which results in decreased secretion of Norepinephrine CTD PMID:2884805 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G NPPA natriuretic peptide A increases expression EXP Propranolol results in increased expression of NPPA protein CTD PMID:2566282 NCBI chr 2:84,406,317...84,408,115
Ensembl chr 2:84,396,073...84,408,385
JBrowse link
G REN renin multiple interactions
decreases activity
EXP Propranolol inhibits the reaction [Isoproterenol results in increased activity of REN protein]
Propranolol results in decreased activity of REN protein
CTD PMID:2566282 PMID:6103674 NCBI chr38:744,540...766,998
Ensembl chr38:744,614...755,012
JBrowse link
G VIP vasoactive intestinal peptide decreases expression EXP Propranolol results in decreased expression of VIP protein CTD PMID:2566282 NCBI chr 1:42,941,655...42,950,160
Ensembl chr 1:42,941,224...42,950,700
JBrowse link
WIN 55212-2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNR2 cannabinoid receptor 2 affects binding EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to CNR2 protein CTD PMID:21871882 NCBI chr 2:75,640,636...75,662,000
Ensembl chr 2:75,658,999...75,660,126
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 501
    role 501
      biological role 501
        biochemical role 460
          apoptosis inhibitor 6
            (+)-schisandrin B 0
            (4Z,7Z,10Z,12E,14S,16Z,19Z,21R)-dihydroxydocosahexaenoic acid 0
            (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside 0
            (Z)-3-(4-iodophenyl)-2-mercaptoacrylic acid 0
            GRI977143 0
            Genipin 0
            HU-308 0
            JWH-133 0
            PR-39 0
            WIN 55212-2 1
            Z-DEVD-FMK 0
            Z-Val-Ala-Asp(OMe)-CH2F 0
            Z-Val-Phe-H 0
            abyssinone I 0
            aspartame 0
            beauvericin 0
            bis(2-ethylhexyl) phthalate 1
            bis(7)-tacrine 0
            bongkrekic acid 0
            carboxy-PTIO 0
            ferulic acid + 0
            fostriecin 0
            fraxetin + 0
            fucoidan 0
            fucoxanthin 0
            gentisyl alcohol 0
            ginsenoside F1 0
            ginsenoside Rb1 0
            isoformononetin 0
            molsidomine 0
            naphthalene + 4
            p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe 0
            potassium 2-(4-carboxylatophenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide 0
            protectin D1 + 0
            salvigenin 0
            sodium ferulate 0
            suramin 0
            suramin sodium 0
            tauroursodeoxycholic acid 0
            tepoxalin 0
            tetramethylpyrazine 0
            triacsin C 0
            tropisetron 0
            tropisetron hydrochloride 0
            zofenopril 0
            zofenopril calcium 0
            zofenoprilat 0
            zofenoprilat arginine 0
paths to the root