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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrimidine deoxyribonucleoside
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Accession:CHEBI:68472 term browser browse the term
Definition:A deoxyribonucleoside containing a pyrimidine base.
Synonyms:related_synonym: pyrimidine deoxyribonucleosides
 xref: MetaCyc:Pyrimidine-Deoxyribonucleosides


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2'-deoxycytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein] CTD PMID:9297556 PMID:9403342 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Dck deoxycytidine kinase affects binding ISO Deoxycytidine binds to DCK protein CTD PMID:17530837 NCBI chr 5:88,765,013...88,783,277
Ensembl chr 5:88,764,996...88,783,281
JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 increases transport ISO SLC28A1 protein results in increased transport of Deoxycytidine CTD PMID:10772724 NCBI chr 7:81,113,269...81,170,416
Ensembl chr 7:81,114,799...81,170,416
JBrowse link
5-bromo-2'-deoxyuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef26 Rho guanine nucleotide exchange factor (GEF) 26 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] affects the expression of ARHGEF26 mRNA CTD PMID:24910943 NCBI chr 3:62,338,777...62,462,221
Ensembl chr 3:62,338,344...62,462,221
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 decreases expression EXP Bromodeoxyuridine results in decreased expression of ATOH8 mRNA CTD PMID:24910943 NCBI chr 6:72,206,174...72,235,780
Ensembl chr 6:72,206,177...72,235,577
JBrowse link
G Bax BCL2-associated X protein multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of BAX mRNA CTD PMID:24910943 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of BIRC5 mRNA CTD PMID:24910943 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of CDKN1A mRNA CTD PMID:24910943 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Ces2b carboxyesterase 2B multiple interactions EXP [Bromodeoxyuridine co-treated with furan] affects the expression of CES2B mRNA CTD PMID:24910943 NCBI chr 8:104,828,494...104,840,093
Ensembl chr 8:104,831,572...104,840,093
JBrowse link
G Ces2c carboxylesterase 2C multiple interactions EXP [Bromodeoxyuridine co-treated with furan] affects the expression of CES2C mRNA CTD PMID:24910943 NCBI chr 8:104,847,068...104,854,483
Ensembl chr 8:104,847,068...104,854,483
JBrowse link
G Dnase1 deoxyribonuclease I multiple interactions EXP [Bromodeoxyuridine co-treated with furan] affects the expression of DNASE1 mRNA CTD PMID:24910943 NCBI chr16:4,036,958...4,040,024
Ensembl chr16:4,036,942...4,040,024
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of DUSP6 mRNA CTD PMID:24910943 NCBI chr10:99,263,231...99,267,489
Ensembl chr10:99,263,231...99,267,489
JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of DUSP8 mRNA CTD PMID:24910943 NCBI chr 7:142,079,487...142,095,907
Ensembl chr 7:142,079,490...142,095,843
JBrowse link
G Elovl6 ELOVL family member 6, elongation of long chain fatty acids (yeast) increases expression EXP Bromodeoxyuridine results in increased expression of ELOVL6 mRNA CTD PMID:24910943 NCBI chr 3:129,532,386...129,638,495
Ensembl chr 3:129,532,355...129,638,495
JBrowse link
G Fam47e family with sequence similarity 47, member E increases expression EXP Bromodeoxyuridine results in increased expression of FAM47E mRNA CTD PMID:24910943 NCBI chr 5:92,554,960...92,591,285
Ensembl chr 5:92,555,069...92,591,279
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of GCLC mRNA CTD PMID:24910943 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of GDF15 mRNA CTD PMID:24910943 NCBI chr 8:70,629,393...70,632,470
Ensembl chr 8:70,629,393...70,632,456
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of GSTA1 mRNA CTD PMID:24910943 NCBI chr 9:78,230,669...78,242,683
Ensembl chr 9:78,230,656...78,242,684
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions
increases expression
EXP [Bromodeoxyuridine co-treated with furan] affects the expression of HMGCR mRNA
Bromodeoxyuridine results in increased expression of HMGCR mRNA
CTD PMID:24910943 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
affects abundance
EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of HMOX1 mRNA
HMOX1 protein affects the abundance of Bromodeoxyuridine
CTD PMID:17401437 PMID:24910943 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C multiple interactions ISO [HNRNPC protein binds to HNRNPC protein alternative form] which results in decreased susceptibility to Bromodeoxyuridine CTD PMID:16960656 NCBI chr14:52,073,377...52,104,039
Ensembl chr14:52,073,377...52,104,028
JBrowse link
G Itga5 integrin alpha 5 (fibronectin receptor alpha) increases expression ISO Bromodeoxyuridine results in increased expression of ITGA5 mRNA; Bromodeoxyuridine results in increased expression of ITGA5 protein CTD PMID:7519154 NCBI chr15:103,344,286...103,366,791
Ensembl chr15:103,344,286...103,366,763
JBrowse link
G Jun jun proto-oncogene multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of JUN mRNA CTD PMID:24910943 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Keg1 kidney expressed gene 1 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] affects the expression of KEG1 mRNA CTD PMID:24910943 NCBI chr19:12,695,790...12,719,902
Ensembl chr19:12,695,786...12,719,902
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] affects the expression of MOGAT2 mRNA CTD PMID:24910943 NCBI chr 7:99,219,084...99,238,611
Ensembl chr 7:99,219,084...99,238,619
JBrowse link
G Msmo1 methylsterol monoxygenase 1 increases expression EXP Bromodeoxyuridine results in increased expression of MSMO1 mRNA CTD PMID:24910943 NCBI chr 8:64,718,123...64,733,578
Ensembl chr 8:64,718,139...64,733,792
JBrowse link
G Myc myelocytomatosis oncogene multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of MYC mRNA CTD PMID:24910943 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 increases expression EXP Bromodeoxyuridine results in increased expression of NMRK1 mRNA CTD PMID:24910943 NCBI chr19:18,632,016...18,652,428
Ensembl chr19:18,631,950...18,652,428
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of NQO1 mRNA CTD PMID:24910943 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G P2ry1 purinergic receptor P2Y, G-protein coupled 1 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] affects the expression of P2RY1 mRNA CTD PMID:24910943 NCBI chr 3:61,002,785...61,008,982
Ensembl chr 3:61,002,795...61,008,982
JBrowse link
G Pax3 paired box 3 increases response to substance EXP PAX3 gene polymorphism results in increased susceptibility to Bromodeoxyuridine CTD PMID:3902948 NCBI chr 1:78,101,267...78,197,136
Ensembl chr 1:78,101,267...78,197,134
JBrowse link
G Scgb1c1 secretoglobin, family 1C, member 1 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] affects the expression of SCGB1C1 mRNA CTD PMID:24910943 NCBI chr 7:140,845,565...140,846,769
Ensembl chr 7:140,845,547...140,846,769
JBrowse link
G Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] affects the expression of SLC17A8 mRNA CTD PMID:24910943 NCBI chr10:89,574,020...89,621,249
Ensembl chr10:89,574,020...89,621,253
JBrowse link
G Snord3b1 small nucleolar RNA, C/D box 3B1 decreases expression EXP Bromodeoxyuridine results in decreased expression of SNORD3B1 mRNA CTD PMID:24910943 NCBI chr11:87,443,237...87,443,451
Ensembl chr11:87,443,237...87,443,451
Ensembl chr11:87,443,237...87,443,451
JBrowse link
G Sox17 SRY (sex determining region Y)-box 17 decreases localization ISO Bromodeoxyuridine results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 1:4,490,928...4,497,426
Ensembl chr 1:4,490,931...4,497,354
JBrowse link
G Sqle squalene epoxidase increases expression EXP Bromodeoxyuridine results in increased expression of SQLE mRNA CTD PMID:24910943 NCBI chr15:59,315,092...59,331,193
Ensembl chr15:59,315,077...59,331,192
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of SRXN1 mRNA CTD PMID:24910943 NCBI chr 2:152,105,524...152,111,376
Ensembl chr 2:152,105,516...152,111,376
JBrowse link
G Stmn1 stathmin 1 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of STMN1 mRNA CTD PMID:24910943 NCBI chr 4:134,468,320...134,473,843
Ensembl chr 4:134,468,320...134,473,843
JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of TNFRSF10B mRNA CTD PMID:24910943 NCBI chr14:69,767,472...69,784,411
Ensembl chr14:69,767,472...69,784,411
JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of TNFRSF12A mRNA CTD PMID:24910943 NCBI chr17:23,675,445...23,677,449
Ensembl chr17:23,675,445...23,677,468
JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression EXP Bromodeoxyuridine results in decreased expression of TRIB3 mRNA CTD PMID:24910943 NCBI chr 2:152,337,425...152,344,060
Ensembl chr 2:152,337,422...152,344,032
JBrowse link
G Tubb2a tubulin, beta 2A class IIA multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of TUBB2A mRNA CTD PMID:24910943 NCBI chr13:34,074,278...34,078,008
Ensembl chr13:34,074,274...34,078,007
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions EXP [Bromodeoxyuridine co-treated with furan] results in increased expression of TXNRD1 mRNA CTD PMID:24910943 NCBI chr10:82,833,951...82,897,724
Ensembl chr10:82,833,951...82,897,712
JBrowse link
G Vsnl1 visinin-like 1 decreases response to substance EXP VSNL1 protein results in decreased susceptibility to Bromodeoxyuridine CTD PMID:20419170 NCBI chr12:11,325,257...11,436,578
Ensembl chr12:11,325,242...11,436,613
JBrowse link
5-iodo-2'-deoxyuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbd4 methyl-CpG binding domain protein 4 affects response to substance EXP MBD4 protein affects the susceptibility to Idoxuridine CTD PMID:16885370 NCBI chr 6:115,840,697...115,853,400
Ensembl chr 6:115,840,697...115,853,371
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Idoxuridine results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr16:38,248,349...38,294,849
Ensembl chr16:38,248,323...38,294,824
JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 multiple interactions ISO Idoxuridine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine] CTD PMID:8713072 NCBI chr 7:81,113,269...81,170,416
Ensembl chr 7:81,114,799...81,170,416
JBrowse link
G Tyms thymidylate synthase affects uptake EXP TYMS protein affects the uptake of Idoxuridine CTD PMID:15001691 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
doxifluridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases response to substance ISO ACAA1 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 9:119,148,043...119,157,093
Ensembl chr 9:119,148,023...119,157,093
JBrowse link
G Agr2 anterior gradient 2 increases response to substance ISO AGR2 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr12:35,992,925...36,004,081
Ensembl chr12:35,992,907...36,004,087
JBrowse link
G Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) decreases response to substance ISO AKR1B1 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 6:34,303,930...34,317,489
Ensembl chr 6:34,302,434...34,317,478
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 increases response to substance ISO AKR1C3 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr13:4,132,615...4,150,646
Ensembl chr13:4,132,615...4,150,654
JBrowse link
G Anxa8 annexin A8 decreases response to substance ISO ANXA8 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr14:34,085,979...34,100,571
Ensembl chr14:34,085,981...34,100,571
JBrowse link
G Arl4d ADP-ribosylation factor-like 4D decreases response to substance ISO ARL4D protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr11:101,665,541...101,667,832
Ensembl chr11:101,665,541...101,667,832
JBrowse link
G Axl AXL receptor tyrosine kinase decreases response to substance ISO AXL protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 7:25,756,500...25,788,924
Ensembl chr 7:25,757,273...25,788,705
JBrowse link
G Ccn1 cellular communication network factor 1 decreases response to substance ISO CCN1 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 3:145,646,971...145,649,985
Ensembl chr 3:145,646,976...145,649,981
JBrowse link
G Cib1 calcium and integrin binding 1 (calmyrin) increases response to substance ISO CIB1 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 7:80,227,156...80,232,805
Ensembl chr 7:80,227,147...80,232,813
JBrowse link
G Cldn3 claudin 3 increases response to substance ISO CLDN3 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 5:134,986,214...134,987,476
Ensembl chr 5:134,986,214...134,987,472
JBrowse link
G Dapk1 death associated protein kinase 1 increases response to substance ISO DAPK1 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr13:60,601,723...60,763,191
Ensembl chr13:60,601,947...60,763,191
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression
affects response to substance
decreases response to substance
multiple interactions
ISO doxifluridine affects the expression of DPYD mRNA
DPYD protein affects the susceptibility to doxifluridine
DPYD protein results in decreased susceptibility to doxifluridine
[Paclitaxel co-treated with doxifluridine] affects the expression of DPYD mRNA
CTD PMID:16646564 PMID:16734730 PMID:18630517 NCBI chr 3:118,562,109...119,432,924
Ensembl chr 3:118,562,129...119,432,924
JBrowse link
G Dse dermatan sulfate epimerase decreases response to substance ISO DSE protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr10:34,151,389...34,208,282
Ensembl chr10:34,151,393...34,207,715
JBrowse link
G Elf3 E74-like factor 3 increases response to substance ISO ELF3 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 1:135,253,574...135,258,472
Ensembl chr 1:135,253,575...135,258,568
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 increases response to substance ISO EPS8 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 6:137,477,245...137,649,397
Ensembl chr 6:137,477,245...137,654,876
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 increases response to substance ISO ERBB3 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr10:128,567,523...128,589,635
Ensembl chr10:128,567,523...128,589,652
JBrowse link
G Etnk1 ethanolamine kinase 1 increases response to substance ISO ETNK1 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 6:143,166,866...143,208,546
Ensembl chr 6:143,167,221...143,232,307
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases response to substance ISO FHL1 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr  X:56,731,209...56,793,346
Ensembl chr  X:56,731,787...56,793,346
JBrowse link
G Flii flightless I actin binding protein decreases response to substance ISO FLII protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr11:60,714,143...60,727,263
Ensembl chr11:60,714,123...60,727,263
JBrowse link
G Fuca1 fucosidase, alpha-L- 1, tissue increases response to substance ISO FUCA1 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 4:135,920,726...135,940,300
Ensembl chr 4:135,920,735...135,940,311
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit decreases response to substance ISO HIF1A protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hras Harvey rat sarcoma virus oncogene decreases response to substance ISO HRAS protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Ifng interferon gamma multiple interactions ISO [IFNG protein results in increased expression of TYMP protein] which results in increased susceptibility to doxifluridine CTD PMID:15301717 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il17rb interleukin 17 receptor B increases response to substance ISO IL17RB protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr14:29,996,168...30,008,896
Ensembl chr14:29,996,135...30,008,896
JBrowse link
G Lgals4 lectin, galactose binding, soluble 4 increases response to substance ISO LGALS4 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 7:28,833,122...28,841,710
Ensembl chr 7:28,833,854...28,841,708
JBrowse link
G Mre11a MRE11A homolog A, double strand break repair nuclease decreases response to substance ISO MRE11 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 9:14,784,654...14,837,125
Ensembl chr 9:14,784,654...14,837,123
JBrowse link
G Myb myeloblastosis oncogene increases response to substance ISO MYB protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr10:21,124,930...21,160,984
Ensembl chr10:21,124,935...21,160,984
JBrowse link
G Nme7 NME/NM23 family member 7 decreases response to substance ISO NME7 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 1:164,307,524...164,437,300
Ensembl chr 1:164,304,121...164,437,725
JBrowse link
G Osmr oncostatin M receptor decreases response to substance ISO OSMR protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr15:6,813,568...6,874,968
Ensembl chr15:6,813,577...6,874,969
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel decreases response to substance ISO PKD2 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 5:104,453,982...104,505,819
Ensembl chr 5:104,459,450...104,505,819
JBrowse link
G Pkp2 plakophilin 2 increases response to substance ISO PKP2 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr16:16,213,345...16,272,712
Ensembl chr16:16,213,318...16,272,712
JBrowse link
G Plce1 phospholipase C, epsilon 1 increases response to substance ISO PLCE1 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr19:38,481,034...38,785,105
Ensembl chr19:38,481,109...38,785,030
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 decreases response to substance ISO PLOD2 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 9:92,539,636...92,608,428
Ensembl chr 9:92,542,223...92,608,428
JBrowse link
G Prkacb protein kinase, cAMP dependent, catalytic, beta decreases response to substance ISO PRKACB protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 3:146,729,579...146,812,946
Ensembl chr 3:146,729,574...146,812,990
JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 decreases response to substance ISO PTPN13 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 5:103,425,192...103,598,361
Ensembl chr 5:103,425,192...103,598,303
JBrowse link
G Pygb brain glycogen phosphorylase increases response to substance ISO PYGB protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 2:150,786,796...150,831,748
Ensembl chr 2:150,786,735...150,831,758
JBrowse link
G Rab40b Rab40B, member RAS oncogene family increases response to substance ISO RAB40B protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr11:121,356,121...121,388,251
Ensembl chr11:121,356,125...121,388,251
JBrowse link
G Rpa1 replication protein A1 decreases response to substance ISO RPA1 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr11:75,300,259...75,348,454
Ensembl chr11:75,298,166...75,348,324
JBrowse link
G Rras2 related RAS viral (r-ras) oncogene 2 decreases response to substance ISO RRAS2 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 7:114,046,782...114,117,781
Ensembl chr 7:114,046,782...114,117,781
JBrowse link
G Sinhcaf SIN3-HDAC complex associated factor increases response to substance ISO SINHCAF protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 6:148,921,057...148,946,470
Ensembl chr 6:148,921,035...148,946,467
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases response to substance ISO STIP1 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr19:7,020,696...7,040,026
Ensembl chr19:7,020,702...7,039,967
JBrowse link
G Tead1 TEA domain family member 1 decreases response to substance ISO TEAD1 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 7:112,679,356...112,906,784
Ensembl chr 7:112,679,318...112,906,807
JBrowse link
G Tff1 trefoil factor 1 increases response to substance ISO TFF1 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr17:31,161,395...31,165,060
Ensembl chr17:31,161,395...31,165,277
JBrowse link
G Thbs1 thrombospondin 1 decreases response to substance ISO THBS1 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 NCBI chr 2:118,111,876...118,127,133
Ensembl chr 2:118,111,876...118,127,133
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
doxifluridine promotes the reaction [TNF protein results in increased expression of TYMP mRNA]
5-benzylacyclouridine inhibits the reaction [[TNF protein results in increased activity of UPP1 protein] which results in increased susceptibility to doxifluridine]; [TNF protein results in increased activity of UPP1 protein] which results in increased susceptibility to doxifluridine; [TNF protein results in increased expression of UPP1 mRNA] which results in increased susceptibility to doxifluridine
CTD PMID:16397116 PMID:17988526 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tymp thymidine phosphorylase multiple interactions
increases metabolic processing
increases response to substance
affects expression
ISO
EXP
[5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride results in decreased activity of TYMP protein] results in decreased susceptibility to [Zidovudine co-treated with doxifluridine]; [5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride results in decreased activity of TYMP protein] which results in decreased susceptibility to doxifluridine; [IFNG protein results in increased expression of TYMP protein] which results in increased susceptibility to doxifluridine; [Paclitaxel co-treated with doxifluridine] affects the expression of TYMP mRNA; [TYMP protein results in increased expression of IFNA1 mRNA] which results in increased susceptibility to doxifluridine; [Zidovudine results in increased activity of TYMP protein] which results in increased susceptibility to doxifluridine; doxifluridine promotes the reaction [TNF protein results in increased expression of TYMP mRNA]
TYMP protein results in increased metabolism of doxifluridine
TYMP protein results in increased susceptibility to doxifluridine
doxifluridine affects the expression of TYMP mRNA
CTD PMID:15301717 PMID:15864645 PMID:16457948 PMID:17988526 PMID:18630517 PMID:21804305 NCBI chr15:89,371,631...89,377,036
Ensembl chr15:89,371,931...89,377,039
JBrowse link
G Tyms thymidylate synthase affects expression
multiple interactions
decreases response to substance
ISO doxifluridine affects the expression of TYMS mRNA
[Paclitaxel co-treated with doxifluridine] affects the expression of TYMS mRNA
TYMS protein results in decreased susceptibility to doxifluridine
CTD PMID:16734730 PMID:18630517 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
G Upp1 uridine phosphorylase 1 multiple interactions EXP 5-benzylacyclouridine inhibits the reaction [[TNF protein results in increased activity of UPP1 protein] which results in increased susceptibility to doxifluridine]; [TNF protein results in increased activity of UPP1 protein] which results in increased susceptibility to doxifluridine; [TNF protein results in increased expression of UPP1 mRNA] which results in increased susceptibility to doxifluridine CTD PMID:16397116 NCBI chr11:9,118,008...9,136,170
Ensembl chr11:9,118,103...9,136,170
JBrowse link
dTDP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale galactose-4-epimerase, UDP affects binding ISO thymidine 5'-diphosphate binds to GALE protein CTD PMID:25526675 NCBI chr 4:135,963,681...135,968,178
Ensembl chr 4:135,963,727...135,968,178
JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 multiple interactions ISO [thymidine 5'-diphosphate co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 1:43,746,961...43,827,839
Ensembl chr 1:43,746,966...43,827,800
JBrowse link
dTMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Thymidine Monophosphate] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
G Tyms thymidylate synthase multiple interactions EXP [Fluorouracil results in decreased activity of TYMS protein] which results in decreased abundance of Thymidine Monophosphate CTD PMID:29258758 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
floxuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endonuclease 1 increases response to substance
decreases response to substance
ISO APEX1 protein mutant form results in increased susceptibility to Floxuridine
APEX1 protein results in decreased susceptibility to Floxuridine
CTD PMID:19470598 PMID:22194930 NCBI chr14:50,924,949...50,927,188
Ensembl chr14:50,924,968...50,927,139
JBrowse link
G Atr ataxia telangiectasia and Rad3 related decreases response to substance ISO ATR protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 PMID:22194930 NCBI chr 9:95,857,597...95,953,217
Ensembl chr 9:95,857,597...95,951,781
JBrowse link
G C1qbp complement component 1, q subcomponent binding protein decreases response to substance ISO C1QBP protein results in decreased susceptibility to Floxuridine CTD PMID:25354864 NCBI chr11:70,977,846...70,983,026
Ensembl chr11:70,977,836...70,983,026
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO Floxuridine results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:21613406 PMID:22194930 NCBI chr 9:36,708,482...36,726,658
Ensembl chr 9:36,708,482...36,727,065
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases activity
ISO Floxuridine results in increased phosphorylation of and results in increased activity of CHEK2 protein
Floxuridine results in increased activity of CHEK2 protein
CTD PMID:21613406 PMID:22194930 NCBI chr 5:110,839,800...110,874,140
Ensembl chr 5:110,839,979...110,874,145
JBrowse link
G Mlh1 mutL homolog 1 multiple interactions
decreases response to substance
ISO olaparib inhibits the reaction [MLH1 protein results in decreased susceptibility to Floxuridine] CTD PMID:22194930 NCBI chr 9:111,228,228...111,271,786
Ensembl chr 9:111,228,228...111,271,791
JBrowse link
G Msh2 mutS homolog 2 multiple interactions
decreases response to substance
ISO olaparib inhibits the reaction [MSH2 protein results in decreased susceptibility to Floxuridine] CTD PMID:22194930 NCBI chr17:87,672,532...87,723,713
Ensembl chr17:87,672,330...87,723,713
JBrowse link
G Mthfr methylenetetrahydrofolate reductase affects response to substance ISO MTHFR protein affects the susceptibility to Floxuridine CTD PMID:18202788 NCBI chr 4:148,039,077...148,059,562
Ensembl chr 4:148,039,077...148,059,551
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 decreases response to substance ISO PARP1 protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Timp3 tissue inhibitor of metalloproteinase 3 affects response to substance
decreases response to substance
ISO TIMP3 protein affects the susceptibility to Floxuridine
TIMP3 gene modified form results in decreased susceptibility to Floxuridine
CTD PMID:18202788 NCBI chr10:86,300,412...86,349,505
Ensembl chr10:86,300,372...86,349,506
JBrowse link
G Tk1 thymidine kinase 1 increases expression ISO Floxuridine results in increased expression of TK1 protein CTD PMID:16951200 NCBI chr11:117,815,519...117,826,087
Ensembl chr11:117,815,526...117,826,092
JBrowse link
G Trp53 transformation related protein 53 increases expression ISO Floxuridine results in increased expression of TP53 protein CTD PMID:19015155 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Tyms thymidylate synthase decreases response to substance
increases response to substance
affects response to substance
ISO TYMS protein results in decreased susceptibility to Floxuridine
TYMS results in increased susceptibility to Floxuridine
TYMS protein affects the susceptibility to Floxuridine
CTD PMID:2537495 PMID:10482907 PMID:15040806 PMID:17018589 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
G Ung uracil DNA glycosylase affects expression
increases response to substance
affects stability
ISO Floxuridine affects the expression of UNG mRNA; Floxuridine affects the expression of UNG protein
UNG protein results in increased susceptibility to Floxuridine
Floxuridine affects the stability of UNG protein alternative form
CTD PMID:16951200 NCBI chr 5:114,130,366...114,139,321
Ensembl chr 5:114,130,386...114,139,323
JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 decreases response to substance ISO XRCC1 protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 PMID:22194930 NCBI chr 7:24,546,699...24,573,438
Ensembl chr 7:24,546,289...24,573,440
JBrowse link
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 decreases response to substance ISO XRCC4 results in decreased susceptibility to Floxuridine CTD PMID:21785230 NCBI chr13:89,848,914...90,089,608
Ensembl chr13:89,774,027...90,089,608
JBrowse link
gemcitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression ISO gemcitabine results in increased expression of A2M protein CTD PMID:20531411 NCBI chr 6:121,636,165...121,679,238
Ensembl chr 6:121,635,376...121,679,227
JBrowse link
G Acpp acid phosphatase, prostate decreases expression ISO gemcitabine results in decreased expression of ACP3 protein CTD PMID:20531411 NCBI chr 9:104,288,240...104,337,722
Ensembl chr 9:104,288,251...104,337,748
JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 multiple interactions ISO ADAM17 protein promotes the reaction [gemcitabine results in increased cleavage of AREG protein] CTD PMID:20726858 NCBI chr12:21,323,509...21,373,632
Ensembl chr12:21,323,509...21,373,632
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO gemcitabine results in increased expression of ADIPOQ protein CTD PMID:20531411 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Afp alpha fetoprotein decreases expression ISO gemcitabine results in decreased expression of AFP protein CTD PMID:20531411 NCBI chr 5:90,490,714...90,508,907
Ensembl chr 5:90,490,737...90,508,907
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) decreases expression ISO gemcitabine results in decreased expression of AGPAT2 mRNA CTD PMID:17039268 NCBI chr 2:26,593,057...26,604,417
Ensembl chr 2:26,593,057...26,604,417
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 affects response to substance
multiple interactions
ISO AKT1 protein affects the susceptibility to gemcitabine
[gemcitabine co-treated with licoricidin] results in decreased phosphorylation of AKT1 protein; [licoricidin co-treated with gemcitabine] results in decreased phosphorylation of AKT1 protein
CTD PMID:15867245 PMID:29782821 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 decreases expression
multiple interactions
ISO gemcitabine results in decreased expression of ALDH1A1 protein
sulforaphane promotes the reaction [gemcitabine results in decreased expression of ALDH1A1 protein]
CTD PMID:20940707 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 increases expression ISO gemcitabine results in increased expression of ALDH1A3 mRNA CTD PMID:17039268 NCBI chr 7:66,390,892...66,427,477
Ensembl chr 7:66,390,890...66,427,517
JBrowse link
G Aldh6a1 aldehyde dehydrogenase family 6, subfamily A1 increases expression ISO gemcitabine results in increased expression of ALDH6A1 mRNA CTD PMID:17039268 NCBI chr12:84,430,717...84,451,024
Ensembl chr12:84,430,717...84,451,004
JBrowse link
G Anapc1 anaphase promoting complex subunit 1 increases expression ISO gemcitabine results in increased expression of ANAPC1 mRNA CTD PMID:17039268 NCBI chr 2:128,610,083...128,687,406
Ensembl chr 2:128,610,104...128,687,391
JBrowse link
G Ank3 ankyrin 3, epithelial increases expression ISO gemcitabine results in increased expression of ANK3 mRNA CTD PMID:17039268 NCBI chr10:69,533,486...70,027,436
Ensembl chr10:69,398,773...70,027,438
JBrowse link
G Ankrd1 ankyrin repeat domain 1 (cardiac muscle) increases expression ISO gemcitabine results in increased expression of ANKRD1 mRNA CTD PMID:17039268 NCBI chr19:36,111,965...36,119,844
Ensembl chr19:36,111,961...36,120,099
JBrowse link
G Antxr1 anthrax toxin receptor 1 affects expression ISO gemcitabine affects the expression of ANTXR1 mRNA CTD PMID:17039268 NCBI chr 6:87,133,853...87,335,809
Ensembl chr 6:87,133,853...87,335,821
JBrowse link
G Apcs amyloid P component, serum decreases expression ISO gemcitabine results in decreased expression of APCS protein CTD PMID:20531411 NCBI chr 1:172,893,961...172,895,054
Ensembl chr 1:172,893,961...172,895,041
JBrowse link
G Apoh apolipoprotein H increases expression ISO gemcitabine results in increased expression of APOH protein CTD PMID:20531411 NCBI chr11:108,395,297...108,414,396
Ensembl chr11:108,343,354...108,414,396
JBrowse link
G Ar androgen receptor multiple interactions ISO gemcitabine binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Areg amphiregulin multiple interactions
increases expression
increases cleavage
decreases response to substance
ISO ADAM17 protein promotes the reaction [gemcitabine results in increased cleavage of AREG protein]
gemcitabine results in increased expression of AREG protein
AREG protein results in decreased susceptibility to gemcitabine
CTD PMID:20726858 NCBI chr 5:91,139,599...91,148,432
Ensembl chr 5:91,139,599...91,148,432
JBrowse link
G Arf1 ADP-ribosylation factor 1 decreases expression ISO gemcitabine results in decreased expression of ARF1 mRNA CTD PMID:17039268 NCBI chr11:59,211,412...59,228,267
Ensembl chr11:59,211,412...59,228,270
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO gemcitabine results in increased expression of ARNT mRNA CTD PMID:20103597 NCBI chr 3:95,434,367...95,497,240
Ensembl chr 3:95,434,388...95,497,240
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO gemcitabine results in increased expression of ATF3 mRNA CTD PMID:17039268 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Axin2 axin 2 affects expression ISO gemcitabine affects the expression of AXIN2 mRNA CTD PMID:20103597 NCBI chr11:108,917,828...108,950,783
Ensembl chr11:108,920,349...108,950,783
JBrowse link
G Axl AXL receptor tyrosine kinase multiple interactions ISO AXL protein promotes the reaction [Warfarin results in increased susceptibility to gemcitabine] CTD PMID:26206560 NCBI chr 7:25,756,500...25,788,924
Ensembl chr 7:25,757,273...25,788,705
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO [alvocidib co-treated with gemcitabine] results in increased expression of BAX protein; [ICI 118551 co-treated with gemcitabine] results in increased expression of BAX protein; [Mastic Resin co-treated with gemcitabine] results in increased expression of BAX protein; [TNFSF10 co-treated with gemcitabine] affects the localization of BAX protein CTD PMID:15770523 PMID:17671697 PMID:20523344 PMID:21570961 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
ISO
EXP
gemcitabine results in decreased expression of BCL2 protein
[alvocidib co-treated with gemcitabine] results in decreased expression of BCL2 protein; [Aminophylline co-treated with gemcitabine] results in decreased expression of BCL2 protein; [ICI 118551 co-treated with gemcitabine] results in decreased expression of BCL2 protein; [Mastic Resin co-treated with gemcitabine] results in decreased expression of BCL2 protein; [Theophylline co-treated with gemcitabine] results in decreased expression of BCL2 protein; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 mRNA]; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; U 0126 inhibits the reaction [gemcitabine results in decreased expression of BCL2 protein]
[Curcumin co-treated with gemcitabine] results in decreased expression of BCL2 protein
CTD PMID:15476743 PMID:15645133 PMID:15770523 PMID:16929163 PMID:17440100 PMID:20523344 PMID:21570961 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions
decreases expression
ISO
EXP
gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 mRNA]; gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 protein]
[Curcumin co-treated with gemcitabine] results in decreased expression of BCL2L1 protein
gemcitabine results in decreased expression of BCL2L1 protein
CTD PMID:15476743 PMID:16929163 PMID:17440100 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728
JBrowse link
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) increases expression ISO gemcitabine results in increased expression of BCL2L11 mRNA CTD PMID:17039268 NCBI chr 2:128,126,038...128,162,547
Ensembl chr 2:128,126,038...128,162,547
JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 increases expression ISO gemcitabine results in increased expression of BCL6 mRNA CTD PMID:17039268 NCBI chr16:23,965,050...23,988,866
Ensembl chr16:23,965,052...23,988,852
JBrowse link
G Bdnf brain derived neurotrophic factor decreases expression ISO gemcitabine results in decreased expression of BDNF protein CTD PMID:20531411 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage ISO gemcitabine results in increased cleavage of BID protein CTD PMID:14750167 NCBI chr 6:120,893,119...120,917,062
Ensembl chr 6:120,891,930...120,916,853
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO gemcitabine results in increased expression of BIRC2 mRNA CTD PMID:17039268 NCBI chr 9:7,818,226...7,837,131
Ensembl chr 9:7,818,227...7,837,064
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 affects expression
multiple interactions
ISO
EXP
gemcitabine affects the expression of BIRC3 mRNA
[Curcumin co-treated with gemcitabine] results in decreased expression of BIRC3 protein
CTD PMID:17039268 PMID:17440100 NCBI chr 9:7,847,468...7,873,205
Ensembl chr 9:7,848,699...7,873,186
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO
EXP
gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 mRNA]; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 protein]
[Curcumin co-treated with gemcitabine] results in decreased expression of BIRC5 protein
CTD PMID:16929163 PMID:17440100 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like increases expression ISO gemcitabine results in increased expression of BNIP3L mRNA CTD PMID:17039268 NCBI chr14:66,985,238...67,008,877
Ensembl chr14:66,985,239...67,008,877
JBrowse link
G Braf Braf transforming gene decreases expression ISO gemcitabine results in decreased expression of BRAF mRNA CTD PMID:20103597 NCBI chr 6:39,603,231...39,725,658
Ensembl chr 6:39,603,237...39,725,463
JBrowse link
G Brca1 breast cancer 1, early onset increases expression
decreases response to substance
ISO
EXP
gemcitabine results in increased expression of BRCA1 mRNA
BRCA1 results in decreased susceptibility to gemcitabine
CTD PMID:20103597 PMID:21771338 NCBI chr11:101,488,761...101,551,955
Ensembl chr11:101,488,764...101,551,955
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
increases cleavage
ISO
EXP
gemcitabine results in increased activity of CASP3 protein
gemcitabine results in increased expression of CASP3 protein modified form
[10-propargyl-10-deazaaminopterin co-treated with gemcitabine] results in increased activity of CASP3 protein; [Curcumin co-treated with gemcitabine] results in decreased expression of CASP3 protein
gemcitabine results in increased cleavage of CASP3 protein
[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with gemcitabine] affects the activity of CASP3 protein; [3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with gemcitabine] affects the activity of CASP3 protein; [alvocidib co-treated with gemcitabine] results in increased cleavage of CASP3 protein; [Calcitriol co-treated with gemcitabine] results in increased expression of CASP3 protein; [gemcitabine co-treated with TNFRSF10B] affects the activity of CASP3 protein; [vorinostat co-treated with gemcitabine] results in increased activity of CASP3 protein; gemcitabine results in increased expression of and results in increased activity of CASP3 protein; licoricidin promotes the reaction [gemcitabine results in increased activity of CASP3 protein]; licoricidin promotes the reaction [gemcitabine results in increased expression of and results in increased activity of CASP3 protein]; Quercetin promotes the reaction [gemcitabine results in increased activity of CASP3 protein]; SMG1 protein inhibits the reaction [gemcitabine results in increased activity of CASP3 protein]
CTD PMID:12479703 PMID:15476743 PMID:15726400 PMID:15770523 PMID:16153448 PMID:16467107 PMID:17159604 PMID:17440100 PMID:18089714 PMID:20299819 PMID:20699664 PMID:20798217 PMID:21418860 PMID:26050647 PMID:29782821 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp6 caspase 6 multiple interactions ISO [Calcitriol co-treated with gemcitabine] results in increased expression of CASP6 protein CTD PMID:20699664 NCBI chr 3:129,901,415...129,914,112
Ensembl chr 3:129,901,425...129,914,103
JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
increases activity
ISO [Calcitriol co-treated with gemcitabine] results in increased expression of CASP8 protein; [gemcitabine co-treated with TNFRSF10B] affects the activity of CASP8 protein; [TNFSF10 co-treated with gemcitabine] results in increased activity of CASP8 protein; gemcitabine results in increased activity of and results in increased cleavage of CASP8 protein; SFN protein inhibits the reaction [gemcitabine results in increased activity of and results in increased cleavage of CASP8 protein]; YAP1 protein affects the reaction [gemcitabine results in increased activity of and results in increased cleavage of CASP8 protein]
gemcitabine results in increased cleavage of CASP8 protein
gemcitabine results in increased activity of CASP8 protein
CTD PMID:12479703 PMID:14750167 PMID:17159604 PMID:17671697 PMID:18089714 PMID:20699664 PMID:26894857 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity
ISO
EXP
[Calcitriol co-treated with gemcitabine] results in increased expression of CASP9 protein; Quercetin promotes the reaction [gemcitabine results in increased activity of CASP9 protein]; SMG1 protein inhibits the reaction [gemcitabine results in increased activity of CASP9 protein]
[Curcumin co-treated with gemcitabine] results in decreased expression of CASP9 protein
gemcitabine results in increased cleavage of CASP9 protein
CTD PMID:12479703 PMID:15476743 PMID:15726400 PMID:17159604 PMID:17440100 PMID:20699664 PMID:21418860 PMID:26050647 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 decreases expression ISO gemcitabine results in decreased expression of CCL2 protein CTD PMID:20531411 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 increases expression ISO gemcitabine results in increased expression of CCL20 mRNA CTD PMID:17039268 NCBI chr 1:83,116,766...83,119,167
Ensembl chr 1:83,116,766...83,119,167
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 increases expression ISO gemcitabine results in increased expression of CCL3 protein CTD PMID:20531411 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355
JBrowse link
G Ccnb1 cyclin B1 decreases expression
increases expression
ISO gemcitabine results in decreased expression of CCNB1 mRNA
gemcitabine results in increased expression of CCNB1 protein
CTD PMID:11504793 PMID:20103597 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO
EXP
Celecoxib promotes the reaction [gemcitabine results in decreased expression of CCND1 protein]
gemcitabine results in decreased expression of CCND1 mRNA; gemcitabine results in decreased expression of CCND1 protein
[Curcumin co-treated with gemcitabine] results in decreased expression of CCND1 protein
CTD PMID:16060994 PMID:17039268 PMID:17440100 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G Ccng2 cyclin G2 increases expression ISO gemcitabine results in increased expression of CCNG2 mRNA CTD PMID:17039268 NCBI chr 5:93,267,573...93,276,231
Ensembl chr 5:93,267,257...93,276,231
JBrowse link
G Cd40 CD40 antigen decreases expression ISO gemcitabine results in decreased expression of CD40 mRNA; gemcitabine results in decreased expression of CD40 protein CTD PMID:17039268 PMID:20531411 NCBI chr 2:165,055,614...165,071,654
Ensembl chr 2:165,055,627...165,072,948
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO gemcitabine results in decreased expression of CD40LG protein CTD PMID:20531411 NCBI chr  X:57,212,143...57,224,042
Ensembl chr  X:57,212,143...57,224,042
JBrowse link
G Cda cytidine deaminase affects response to substance
multiple interactions
ISO CDA protein affects the susceptibility to gemcitabine
[crizotinib results in decreased expression of CDA protein] which results in increased susceptibility to gemcitabine; CDA protein affects the susceptibility to [gemcitabine co-treated with Mitomycin]; CDA protein affects the susceptibility to [gemcitabine co-treated with oxaliplatin]
CTD PMID:18728667 PMID:22973962 NCBI chr 4:138,338,528...138,368,311
Ensembl chr 4:138,338,424...138,367,992
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [gemcitabine co-treated with ON 01910] results in decreased expression of CDC25C protein CTD PMID:20103597 NCBI chr18:34,732,993...34,751,564
Ensembl chr18:34,732,993...34,751,533
JBrowse link
G Cdh1 cadherin 1 increases expression ISO gemcitabine results in increased expression of CDH1 mRNA CTD PMID:17039268 NCBI chr 8:106,603,350...106,670,247
Ensembl chr 8:106,603,351...106,670,246
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions
increases expression
ISO [alvocidib co-treated with gemcitabine] results in increased expression of CDKN1A protein; [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of CDKN1A protein; Nicotine inhibits the reaction [gemcitabine results in increased expression of CDKN1A protein]
gemcitabine results in increased expression of CDKN1A mRNA; gemcitabine results in increased expression of CDKN1A protein
CTD PMID:15476743 PMID:15770523 PMID:16601104 PMID:17039268 PMID:25189999 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases response to substance ISO CDKN1B results in decreased susceptibility to gemcitabine CTD PMID:21652059 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta increases expression ISO gemcitabine results in increased expression of CEBPB mRNA CTD PMID:17039268 NCBI chr 2:167,688,915...167,690,432
Ensembl chr 2:167,688,915...167,690,418
JBrowse link
G Chrdl2 chordin-like 2 multiple interactions ISO [gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of CHRDL2 protein CTD PMID:24979617 NCBI chr 7:100,006,404...100,034,728
Ensembl chr 7:100,006,172...100,034,728
JBrowse link
G Ckb creatine kinase, brain decreases expression ISO gemcitabine results in decreased expression of CKB mRNA CTD PMID:17039268 NCBI chr12:111,669,355...111,672,338
Ensembl chr12:111,669,361...111,672,338
JBrowse link
G Clic4 chloride intracellular channel 4 (mitochondrial) increases expression ISO gemcitabine results in increased expression of CLIC4 mRNA CTD PMID:17039268 NCBI chr 4:135,213,969...135,272,760
Ensembl chr 4:135,213,969...135,272,814
JBrowse link
G Clu clusterin affects response to substance
increases expression
ISO CLU protein affects the susceptibility to gemcitabine
gemcitabine results in increased expression of CLU protein
CTD PMID:19007378 NCBI chr14:65,968,483...65,981,548
Ensembl chr14:65,968,483...65,981,547
JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) multiple interactions
increases expression
ISO BAY 11-7085 inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA]; Dactinomycin inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA] CTD PMID:21525939 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Cnr2 cannabinoid receptor 2 (macrophage) multiple interactions
increases expression
ISO BAY 11-7085 inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA]; Dactinomycin inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA] CTD PMID:21525939 NCBI chr 4:135,895,189...135,920,219
Ensembl chr 4:135,895,394...135,920,207
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) decreases expression ISO gemcitabine results in decreased expression of CSF2 protein CTD PMID:20531411 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) decreases expression ISO gemcitabine results in decreased expression of CSF3 protein CTD PMID:20531411 NCBI chr11:98,700,183...98,703,631
Ensembl chr11:98,701,263...98,703,629
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression ISO gemcitabine results in increased expression of CSRP2 mRNA CTD PMID:17039268 NCBI chr10:110,920,176...110,939,514
Ensembl chr10:110,919,789...110,939,622
JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 increases expression ISO gemcitabine results in increased expression of CTHRC1 mRNA CTD PMID:17039268 NCBI chr15:39,076,932...39,087,121
Ensembl chr15:39,076,932...39,087,121
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 increases expression ISO gemcitabine results in increased expression of CTNNB1 mRNA CTD PMID:25605917 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 increases expression ISO gemcitabine results in increased expression of CXCL1 mRNA CTD PMID:17039268 NCBI chr 5:90,891,245...90,893,121
Ensembl chr 5:90,891,241...90,893,115
JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 multiple interactions ISO [gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of CXCL11 protein CTD PMID:24979617 NCBI chr 5:92,359,544...92,363,296
Ensembl chr 5:92,359,544...92,365,485
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 decreases expression
increases secretion
ISO gemcitabine results in decreased expression of CXCL8 protein
gemcitabine results in increased secretion of CXCL8 protein
CTD PMID:20531411 PMID:28007550 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 increases expression ISO gemcitabine results in increased expression of CXCL2 mRNA CTD PMID:17039268 NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 increases expression ISO gemcitabine results in increased expression of CXCL1 mRNA CTD PMID:17039268 NCBI chr 5:90,786,101...90,788,093
Ensembl chr 5:90,786,103...90,789,600
JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 affects expression ISO gemcitabine affects the expression of CXCR4 mRNA CTD PMID:20103597 NCBI chr 1:128,588,199...128,592,299
Ensembl chr 1:128,588,199...128,592,293
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 decreases expression ISO gemcitabine results in decreased expression of CYP24A1 mRNA CTD PMID:17039268 NCBI chr 2:170,482,957...170,497,145
Ensembl chr 2:170,482,708...170,497,145
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects expression ISO gemcitabine affects the expression of DDIT4 mRNA CTD PMID:17039268 NCBI chr10:59,949,675...59,951,770
Ensembl chr10:59,949,669...59,951,834
JBrowse link
G Dhx9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 decreases expression ISO gemcitabine results in decreased expression of DHX9 mRNA CTD PMID:17039268 NCBI chr 1:153,455,756...153,487,688
Ensembl chr 1:153,455,758...153,487,660
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO gemcitabine results in increased expression of DLG2 mRNA CTD PMID:17039268 NCBI chr 7:90,476,188...92,449,246
Ensembl chr 7:90,476,672...92,449,247
JBrowse link
G Dnmt1 DNA methyltransferase (cytosine-5) 1 multiple interactions ISO [DNMT1 protein binds to SFN promoter] inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine]; [gemcitabine results in decreased susceptibility to gemcitabine] inhibits the reaction [DNMT1 protein binds to SFN promoter]; [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of DNMT1 protein; [UHRF1 protein promotes the reaction [DNMT1 protein binds to SFN promoter]] inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine]; DNMT1 protein inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine] CTD PMID:25189999 NCBI chr 9:20,907,206...20,959,888
Ensembl chr 9:20,907,209...20,959,888
JBrowse link
G Dnmt3b DNA methyltransferase 3B multiple interactions ISO [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of DNMT3B protein CTD PMID:25189999 NCBI chr 2:153,649,411...153,687,730
Ensembl chr 2:153,649,450...153,687,730
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase multiple interactions ISO [TYMP protein co-treated with DPYD protein] affects the susceptibility to gemcitabine CTD PMID:18728667 NCBI chr 3:118,562,109...119,432,924
Ensembl chr 3:118,562,129...119,432,924
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 decreases expression ISO gemcitabine results in decreased expression of DYNC1H1 mRNA CTD PMID:17039268 NCBI chr12:110,601,395...110,666,944
Ensembl chr12:110,601,452...110,666,945
JBrowse link
G Edn1 endothelin 1 decreases expression ISO gemcitabine results in decreased expression of EDN1 protein CTD PMID:20531411 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990
JBrowse link
G Edn2 endothelin 2 decreases expression ISO gemcitabine results in decreased expression of EDN2 mRNA CTD PMID:17039268 NCBI chr 4:120,161,206...120,167,360
Ensembl chr 4:120,161,206...120,167,360
JBrowse link
G Egf epidermal growth factor multiple interactions
decreases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]; EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]; Erlotinib Hydrochloride inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]; pyrazolanthrone inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]; U 0126 inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]
gemcitabine results in decreased expression of EGF protein
CTD PMID:20531411 PMID:21613822 NCBI chr 3:129,677,574...129,755,322
Ensembl chr 3:129,677,565...129,755,316
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation
increases expression
decreases expression
increases degradation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein]; EGFR gene mutant form results in increased susceptibility to [gemcitabine co-treated with Cisplatin co-treated with Erlotinib Hydrochloride]; gefitinib inhibits the reaction [gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein]; gemcitabine promotes the reaction [HER3 protein binds to EGFR protein]
gemcitabine results in increased phosphorylation of EGFR protein
gemcitabine results in increased expression of EGFR mRNA
gemcitabine results in decreased expression of EGFR mRNA; gemcitabine results in decreased expression of EGFR protein
gemcitabine results in increased degradation of EGFR protein
CTD PMID:17146438 PMID:20103597 PMID:20726858 PMID:21541241 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Egr1 early growth response 1 increases expression ISO gemcitabine results in increased expression of EGR1 mRNA CTD PMID:17039268 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO gemcitabine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Etv1 ets variant 1 increases expression ISO gemcitabine results in increased expression of ETV1 mRNA CTD PMID:17039268 NCBI chr12:38,780,082...38,870,483
Ensembl chr12:38,779,380...38,870,484
JBrowse link
G Evi2b ecotropic viral integration site 2b decreases expression ISO gemcitabine results in decreased expression of EVI2B mRNA CTD PMID:17039268 NCBI chr11:79,513,385...79,523,762
Ensembl chr11:79,515,056...79,523,762
JBrowse link
G F7 coagulation factor VII decreases expression ISO gemcitabine results in decreased expression of F7 protein CTD PMID:20531411 NCBI chr 8:13,025,506...13,035,809
Ensembl chr 8:13,026,034...13,035,809
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) increases expression ISO gemcitabine results in increased expression of FAS mRNA; gemcitabine results in increased expression of FAS protein CTD PMID:11138460 PMID:17159604 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Fbxo25 F-box protein 25 increases expression ISO gemcitabine results in increased expression of FBXO25 mRNA CTD PMID:17039268 NCBI chr 8:13,907,736...13,942,875
Ensembl chr 8:13,907,803...13,940,522
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions
increases expression
ISO [gemcitabine co-treated with IFNA2 protein] results in increased expression of FGF2 protein
gemcitabine results in increased expression of FGF2 protein
CTD PMID:12738744 PMID:20531411 NCBI chr 3:37,348,477...37,410,106
Ensembl chr 3:37,348,346...37,410,108
JBrowse link
G Fgg fibrinogen gamma chain affects expression ISO gemcitabine affects the expression of FGG mRNA CTD PMID:17039268 NCBI chr 3:83,007,724...83,015,056
Ensembl chr 3:83,007,724...83,015,049
JBrowse link
G Fosl2 fos-like antigen 2 decreases expression ISO gemcitabine results in decreased expression of FOSL2 mRNA CTD PMID:17039268 NCBI chr 5:32,136,472...32,157,840
Ensembl chr 5:32,135,801...32,157,842
JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 increases expression ISO gemcitabine results in increased expression of FXYD3 mRNA CTD PMID:17039268 NCBI chr 7:31,070,535...31,076,697
Ensembl chr 7:31,068,172...31,076,704
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 decreases expression ISO gemcitabine results in decreased expression of GAL3ST1 mRNA CTD PMID:17039268 NCBI chr11:3,983,636...3,999,328
Ensembl chr11:3,983,636...3,999,326
JBrowse link
G Gas1 growth arrest specific 1 decreases expression ISO gemcitabine results in decreased expression of GAS1 mRNA CTD PMID:17039268 NCBI chr13:60,174,405...60,177,535
Ensembl chr13:60,174,405...60,177,365
JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO gemcitabine results in decreased expression of GASK1B mRNA CTD PMID:17039268 NCBI chr 3:79,884,484...79,946,278
Ensembl chr 3:79,884,533...79,946,280
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of GDF15 protein CTD PMID:24979617 NCBI chr 8:70,629,393...70,632,470
Ensembl chr 8:70,629,393...70,632,456
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 affects response to substance ISO GIPC1 affects the susceptibility to gemcitabine CTD PMID:25469510 NCBI chr 8:83,649,408...83,664,789
Ensembl chr 8:83,652,677...83,664,694
JBrowse link
G Gli2 GLI-Kruppel family member GLI2 affects expression ISO gemcitabine affects the expression of GLI2 mRNA CTD PMID:20103597 NCBI chr 1:118,834,061...119,054,405
Ensembl chr 1:118,834,132...119,053,619
JBrowse link
G Glrx glutaredoxin increases expression ISO gemcitabine results in increased expression of GLRX mRNA CTD PMID:17039268 NCBI chr13:75,839,885...75,850,151
Ensembl chr13:75,839,868...75,850,154
JBrowse link
G Gpc3 glypican 3 increases expression ISO gemcitabine results in increased expression of GPC3 mRNA CTD PMID:17039268 NCBI chr  X:52,272,426...52,613,974
Ensembl chr  X:52,272,426...52,613,950
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO gemcitabine results in increased phosphorylation of GSK3B protein CTD PMID:16570353 NCBI chr16:38,089,001...38,246,084
Ensembl chr16:38,089,001...38,246,084
JBrowse link
G Gtf2a1 general transcription factor II A, 1 affects expression ISO gemcitabine affects the expression of GTF2A1 mRNA CTD PMID:17039268 NCBI chr12:91,555,262...91,590,487
Ensembl chr12:91,555,262...91,590,487
JBrowse link
G H4c3 H4 clustered histone 3 decreases expression ISO gemcitabine results in decreased expression of H4C3 mRNA CTD PMID:17039268 NCBI chr13:23,698,084...23,698,458
Ensembl chr13:23,697,635...23,698,454
JBrowse link
G Hdac9 histone deacetylase 9 increases expression ISO gemcitabine results in increased expression of HDAC9 mRNA CTD PMID:17039268 NCBI chr12:34,047,580...34,917,095
Ensembl chr12:34,047,580...34,917,095
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit affects response to substance ISO HIF1A protein affects the susceptibility to gemcitabine CTD PMID:16628086 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hoxb2 homeobox B2 increases expression ISO gemcitabine results in increased expression of HOXB2 mRNA CTD PMID:17039268 NCBI chr11:96,351,632...96,354,020
Ensembl chr11:96,350,525...96,354,012
JBrowse link
G Hspa1l heat shock protein 1-like decreases expression ISO gemcitabine results in decreased expression of HSPA1L mRNA CTD PMID:17039268 NCBI chr17:34,972,703...34,979,228
Ensembl chr17:34,972,703...34,979,285
JBrowse link
G Hspa5 heat shock protein 5 increases expression ISO gemcitabine results in increased expression of HSPA5 mRNA CTD PMID:17039268 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
EXP
ISO
[Curcumin co-treated with gemcitabine] results in decreased expression of ICAM1 protein
gemcitabine results in decreased expression of ICAM1 protein
CTD PMID:17440100 PMID:20531411 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Ifng interferon gamma decreases expression ISO gemcitabine results in decreased expression of IFNG protein CTD PMID:20531411 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igf1r insulin-like growth factor I receptor decreases expression ISO gemcitabine results in decreased expression of IGF1R mRNA CTD PMID:20103597 NCBI chr 7:67,952,257...68,233,668
Ensembl chr 7:67,952,827...68,233,668
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 affects expression ISO gemcitabine affects the expression of IGFBP3 mRNA CTD PMID:20103597 NCBI chr11:7,206,086...7,215,498
Ensembl chr11:7,206,086...7,213,923
JBrowse link
G Il10 interleukin 10 decreases expression ISO gemcitabine results in decreased expression of IL10 protein CTD PMID:20531411 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il13 interleukin 13 increases expression ISO gemcitabine results in increased expression of IL13 protein CTD PMID:20531411 NCBI chr11:53,631,323...53,634,702
Ensembl chr11:53,631,324...53,634,702
JBrowse link
G Il15 interleukin 15 decreases expression ISO gemcitabine results in decreased expression of IL15 protein CTD PMID:20531411 NCBI chr 8:82,331,624...82,403,252
Ensembl chr 8:82,331,632...82,403,222
JBrowse link
G Il16 interleukin 16 increases expression ISO gemcitabine results in increased expression of IL16 protein CTD PMID:20531411 NCBI chr 7:83,642,819...83,746,028
Ensembl chr 7:83,642,825...83,745,726
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO gemcitabine results in decreased expression of IL1A protein CTD PMID:20531411 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO gemcitabine results in decreased expression of IL1B protein CTD PMID:20531411 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il4 interleukin 4 decreases expression ISO gemcitabine results in decreased expression of IL4 protein CTD PMID:20531411 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il6 interleukin 6 decreases expression
increases secretion
increases expression
ISO gemcitabine results in decreased expression of IL6 protein
gemcitabine results in increased secretion of IL6 protein
gemcitabine results in increased expression of IL6 mRNA
CTD PMID:17039268 PMID:20531411 PMID:28007550 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Ilk integrin linked kinase affects response to substance ISO ILK protein affects the susceptibility to gemcitabine CTD PMID:15867245 NCBI chr 7:105,736,590...105,742,925
Ensembl chr 7:105,736,592...105,742,925
JBrowse link
G Ins2 insulin II increases expression ISO gemcitabine results in increased expression of INS protein CTD PMID:20531411 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO gemcitabine results in increased expression of INSIG1 mRNA CTD PMID:17039268 NCBI chr 5:28,071,412...28,078,662
Ensembl chr 5:28,071,363...28,078,662
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression ISO gemcitabine results in increased expression of IQGAP1 mRNA CTD PMID:17039268 NCBI chr 7:80,711,583...80,815,549
Ensembl chr 7:80,711,583...80,825,974
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO gemcitabine results in increased expression of IRAK2 mRNA CTD PMID:17039268 NCBI chr 6:113,638,467...113,695,026
Ensembl chr 6:113,638,467...113,695,026
JBrowse link
G Irf3 interferon regulatory factor 3 decreases expression ISO gemcitabine results in decreased expression of IRF3 mRNA CTD PMID:17039268 NCBI chr 7:44,997,648...45,002,848
Ensembl chr 7:44,997,648...45,002,848
JBrowse link
G Itgav integrin alpha V multiple interactions ISO [ITGB6 co-treated with ITGAV] affects the susceptibility to gemcitabine CTD PMID:20150628 NCBI chr 2:83,722,303...83,806,917
Ensembl chr 2:83,724,397...83,806,916
JBrowse link
G Itgb6 integrin beta 6 multiple interactions ISO [ITGB6 co-treated with ITGAV] affects the susceptibility to gemcitabine CTD PMID:20150628 NCBI chr 2:60,598,292...60,722,603
Ensembl chr 2:60,598,292...60,722,643
JBrowse link
G Itsn2 intersectin 2 increases expression ISO gemcitabine results in increased expression of ITSN2 mRNA CTD PMID:17039268 NCBI chr12:4,592,643...4,713,952
Ensembl chr12:4,592,638...4,713,962
JBrowse link
G Jam3 junction adhesion molecule 3 decreases expression ISO gemcitabine results in decreased expression of JAM3 mRNA CTD PMID:17039268 NCBI chr 9:27,097,384...27,155,421
Ensembl chr 9:27,097,384...27,155,421
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [Copper co-treated with Disulfiram co-treated with gemcitabine] results in increased expression of and results in increased phosphorylation of JUN protein CTD PMID:23033007 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kctd12 potassium channel tetramerisation domain containing 12 decreases expression ISO gemcitabine results in decreased expression of KCTD12 mRNA CTD PMID:17039268 NCBI chr14:102,976,581...102,982,637
Ensembl chr14:102,976,581...102,982,637
JBrowse link
G Kitl kit ligand decreases expression
multiple interactions
ISO gemcitabine results in decreased expression of KITLG protein
[gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of KITLG protein
CTD PMID:20531411 PMID:24979617 NCBI chr10:100,015,615...100,100,416
Ensembl chr10:100,015,630...100,100,416
JBrowse link
G Klf8 Kruppel-like factor 8 increases expression ISO gemcitabine results in increased expression of KLF8 mRNA CTD PMID:17039268 NCBI chr  X:153,225,339...153,398,925
Ensembl chr  X:153,237,466...153,396,132
JBrowse link
G Krt8 keratin 8 decreases expression ISO gemcitabine results in decreased expression of KRT8 mRNA CTD PMID:17039268 NCBI chr15:101,996,711...102,004,342
Ensembl chr15:101,996,698...102,004,482
JBrowse link
G Larp4b La ribonucleoprotein domain family, member 4B increases expression ISO gemcitabine results in increased expression of LARP4B mRNA CTD PMID:17039268 NCBI chr13:9,093,653...9,174,451
Ensembl chr13:9,093,881...9,174,451
JBrowse link
G Lep leptin decreases expression ISO gemcitabine results in decreased expression of LEP protein CTD PMID:20531411 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Lifr LIF receptor alpha increases expression ISO gemcitabine results in increased expression of LIFR mRNA CTD PMID:17039268 NCBI chr15:7,090,610...7,197,489
Ensembl chr15:7,090,614...7,197,489
JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 decreases expression ISO gemcitabine results in decreased expression of LPAR6 mRNA CTD PMID:17039268 NCBI chr14:73,237,891...73,240,358
Ensembl chr14:73,237,895...73,243,294
JBrowse link
G Lrrc28 leucine rich repeat containing 28 increases expression ISO gemcitabine results in increased expression of LRRC28 mRNA CTD PMID:17039268 NCBI chr 7:67,513,410...67,645,336
Ensembl chr 7:67,513,410...67,645,268
JBrowse link
G Lta lymphotoxin A increases expression ISO gemcitabine results in increased expression of LTA protein CTD PMID:20531411 NCBI chr17:35,203,165...35,205,578
Ensembl chr17:35,203,165...35,205,351
JBrowse link
G Lyz2 lysozyme 2 decreases expression ISO gemcitabine results in decreased expression of LYZ mRNA CTD PMID:17039268 NCBI chr10:117,277,541...117,282,272
Ensembl chr10:117,277,331...117,282,321
JBrowse link
G Maf avian musculoaponeurotic fibrosarcoma oncogene homolog increases expression ISO gemcitabine results in increased expression of MAF mRNA CTD PMID:17039268 NCBI chr 8:115,703,253...115,706,894
Ensembl chr 8:115,682,942...115,707,794
JBrowse link
G Magea10 MAGE family member A10 decreases expression ISO gemcitabine results in decreased expression of MAGEA10 mRNA CTD PMID:17039268 NCBI chr  X:72,381,870...72,386,858
Ensembl chr  X:72,381,870...72,386,858
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 increases expression ISO gemcitabine results in increased expression of MAGI1 mRNA CTD PMID:17039268 NCBI chr 6:93,675,453...94,283,929
Ensembl chr 6:93,675,455...94,283,917
JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 increases phosphorylation ISO gemcitabine results in increased phosphorylation of MAP2K3 protein CTD PMID:15003513 NCBI chr11:60,932,054...60,952,811
Ensembl chr11:60,932,033...60,952,811
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 increases phosphorylation ISO gemcitabine results in increased phosphorylation of MAP2K6 protein CTD PMID:15003513 NCBI chr11:110,399,102...110,525,522
Ensembl chr11:110,399,122...110,525,522
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO [Copper co-treated with Disulfiram co-treated with gemcitabine] results in increased phosphorylation of MAPK1 protein
gemcitabine results in increased phosphorylation of MAPK1 protein
CTD PMID:15476743 PMID:23033007 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions
ISO gemcitabine results in increased phosphorylation of MAPK3 protein
[Copper co-treated with Disulfiram co-treated with gemcitabine] results in increased phosphorylation of MAPK3 protein
CTD PMID:15476743 PMID:23033007 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression
increases phosphorylation
ISO gemcitabine results in increased expression of MARCKS mRNA
gemcitabine results in increased phosphorylation of MARCKS protein
CTD PMID:9523737 PMID:17039268 NCBI chr10:37,133,243...37,138,926
Ensembl chr10:37,133,375...37,138,920
JBrowse link
G Mars1 methionine-tRNA synthetase 1 increases expression ISO gemcitabine results in increased expression of MARS1 mRNA CTD PMID:17039268 NCBI chr10:127,296,221...127,311,786
Ensembl chr10:127,296,221...127,311,786
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 decreases expression
increases expression
ISO gemcitabine results in decreased expression of MDM2 mRNA
gemcitabine results in increased expression of MDM2 mRNA
CTD PMID:17039268 PMID:20103597 NCBI chr10:117,688,875...117,710,758
Ensembl chr10:117,688,875...117,710,758
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression ISO gemcitabine results in decreased expression of MGMT mRNA CTD PMID:17039268 NCBI chr 7:136,894,463...137,128,193
Ensembl chr 7:136,894,614...137,130,266
JBrowse link
G Mir24-2 microRNA 24-2 multiple interactions ISO MIR24-2 mRNA affects the susceptibility to [betulinic acid co-treated with gemcitabine] CTD PMID:25841339 NCBI chr 8:84,208,815...84,208,921
Ensembl chr 8:84,208,815...84,208,921
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions EXP [Curcumin co-treated with gemcitabine] results in decreased expression of MKI67 protein CTD PMID:17440100 NCBI chr 7:135,689,784...135,716,450
Ensembl chr 7:135,689,784...135,716,361
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression ISO gemcitabine results in decreased expression of MMP3 protein CTD PMID:20531411 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP
ISO
[Curcumin co-treated with gemcitabine] results in decreased expression of MMP9 protein
[gemcitabine co-treated with IFNA2 protein] results in increased expression of MMP9 protein
CTD PMID:12738744 PMID:17440100 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mpo myeloperoxidase increases expression ISO gemcitabine results in increased expression of MPO protein CTD PMID:20531411 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Msln mesothelin multiple interactions ISO gemcitabine results in decreased expression of and results in decreased secretion of MSLN protein alternative form CTD PMID:25347530 NCBI chr17:25,748,613...25,754,378
Ensembl chr17:25,748,613...25,754,378
JBrowse link
G mt-Co3 cytochrome c oxidase III, mitochondrial decreases response to substance
multiple interactions
ISO COX3 protein results in decreased susceptibility to gemcitabine
Sodium Azide inhibits the reaction [COX3 protein results in decreased susceptibility to gemcitabine]
CTD PMID:17428446 NCBI chr MT:8,607...9,390
Ensembl chr MT:8,607...9,390
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO gemcitabine results in increased expression of MXI1 mRNA CTD PMID:17039268 NCBI chr19:53,310,128...53,373,293
Ensembl chr19:53,310,518...53,375,810
JBrowse link
G Myb myeloblastosis oncogene increases expression ISO gemcitabine results in increased expression of MYB mRNA CTD PMID:17039268 NCBI chr10:21,124,930...21,160,984
Ensembl chr10:21,124,935...21,160,984
JBrowse link
G Myc myelocytomatosis oncogene affects response to substance
multiple interactions
ISO
EXP
MYC affects the susceptibility to gemcitabine
[Curcumin co-treated with gemcitabine] results in decreased expression of MYC protein
[Oligonucleotides binds to MYC gene] which results in increased susceptibility to gemcitabine
CTD PMID:17440100 PMID:23681918 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Nanog Nanog homeobox decreases expression ISO gemcitabine results in decreased expression of NANOG mRNA CTD PMID:25605917 NCBI chr 6:122,707,489...122,714,633
Ensembl chr 6:122,707,489...122,714,633
JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 increases expression ISO gemcitabine results in increased expression of NCBP1 mRNA CTD PMID:17039268 NCBI chr 4:46,138,511...46,172,403
Ensembl chr 4:46,138,613...46,172,403
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 increases expression ISO gemcitabine results in increased expression of NEDD9 mRNA CTD PMID:17039268 NCBI chr13:41,309,916...41,487,362
Ensembl chr13:41,309,581...41,487,362
JBrowse link
G Neu1 neuraminidase 1 increases expression ISO gemcitabine results in increased expression of NEU1 mRNA CTD PMID:17039268 NCBI chr17:34,931,253...34,937,297
Ensembl chr17:34,931,253...34,935,953
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases response to substance ISO NFE2L2 protein results in decreased susceptibility to gemcitabine CTD PMID:21489257 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 affects expression ISO gemcitabine affects the expression of NFKB2 mRNA CTD PMID:17039268 NCBI chr19:46,300,994...46,312,400
Ensembl chr19:46,304,320...46,312,385
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO [Mastic Resin co-treated with gemcitabine] results in increased expression of NFKBIA protein CTD PMID:20523344 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon affects expression ISO gemcitabine affects the expression of NFKBIE mRNA CTD PMID:17039268 NCBI chr17:45,555,700...45,563,169
Ensembl chr17:45,555,703...45,563,169
JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression ISO gemcitabine results in increased expression of NNMT mRNA CTD PMID:17039268 NCBI chr 9:48,538,002...48,607,655
Ensembl chr 9:48,591,877...48,605,153
JBrowse link
G Notch1 notch 1 increases expression
multiple interactions
ISO gemcitabine results in increased expression of NOTCH1 protein
sulforaphane inhibits the reaction [gemcitabine results in increased expression of NOTCH1 protein]
CTD PMID:20940707 NCBI chr 2:26,457,902...26,503,822
Ensembl chr 2:26,457,903...26,516,663
JBrowse link
G Npepps aminopeptidase puromycin sensitive decreases expression ISO gemcitabine results in decreased expression of NPEPPS mRNA CTD PMID:17039268 NCBI chr11:97,205,842...97,280,660
Ensembl chr11:97,205,842...97,280,638
JBrowse link
G Npm1 nucleophosmin 1 decreases response to substance ISO NPM1 protein results in decreased susceptibility to gemcitabine CTD PMID:24736981 NCBI chr11:33,152,498...33,164,142
Ensembl chr11:33,152,287...33,163,206
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO gemcitabine results in increased expression of NR4A3 mRNA CTD PMID:17039268 NCBI chr 4:48,045,078...48,086,447
Ensembl chr 4:48,045,153...48,086,447
JBrowse link
G Nrg1 neuregulin 1 increases expression ISO gemcitabine results in increased expression of NRG1 mRNA CTD PMID:17039268 NCBI chr 8:31,807,452...32,891,609
Ensembl chr 8:31,814,551...32,884,797
JBrowse link
G Nrp1 neuropilin 1 decreases response to substance ISO NRP1 protein results in decreased susceptibility to gemcitabine CTD PMID:15956974 NCBI chr 8:128,358,591...128,505,476
Ensembl chr 8:128,358,604...128,503,363
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 decreases expression
affects response to substance
ISO gemcitabine results in decreased expression of NUPR1 mRNA
NUPR1 affects the susceptibility to gemcitabine
CTD PMID:16397047 NCBI chr 7:126,623,246...126,625,470
Ensembl chr 7:126,623,249...126,630,861
JBrowse link
G Olfr1428 olfactory receptor 1428 affects response to substance ISO OR4D6 gene SNP affects the susceptibility to gemcitabine CTD PMID:26378035 NCBI chr19:12,108,600...12,115,828
Ensembl chr19:12,107,716...12,115,897
JBrowse link
G Osm oncostatin M multiple interactions ISO [gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of OSM protein CTD PMID:24979617 NCBI chr11:4,236,785...4,241,026
Ensembl chr11:4,236,420...4,241,026
JBrowse link
G Pappa pregnancy-associated plasma protein A decreases expression ISO gemcitabine results in decreased expression of PAPPA protein CTD PMID:20531411 NCBI chr 4:65,124,174...65,357,509
Ensembl chr 4:65,124,174...65,357,509
JBrowse link
G Paqr8 progestin and adipoQ receptor family member VIII increases expression ISO gemcitabine results in increased expression of PAQR8 mRNA CTD PMID:17039268 NCBI chr 1:20,890,548...20,939,650
Ensembl chr 1:20,890,606...20,939,650
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases cleavage
ISO [alvocidib co-treated with gemcitabine] results in increased cleavage of PARP1 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [gemcitabine results in increased cleavage of PARP1 protein]; SFN protein inhibits the reaction [gemcitabine results in increased cleavage of PARP1 protein]; YAP1 protein affects the reaction [gemcitabine results in increased cleavage of PARP1 protein] CTD PMID:15770523 PMID:17146438 PMID:26894857 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Parp2 poly (ADP-ribose) polymerase family, member 2 decreases response to substance ISO PARP2 protein results in decreased susceptibility to gemcitabine CTD PMID:20798217 NCBI chr14:50,807,897...50,821,301
Ensembl chr14:50,807,841...50,821,301
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression ISO gemcitabine results in increased expression of PCSK9 mRNA CTD PMID:17039268 NCBI chr 4:106,442,334...106,464,325
Ensembl chr 4:106,442,329...106,464,329
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 decreases response to substance ISO PDPK1 protein modified form results in decreased susceptibility to gemcitabine CTD PMID:16782806 NCBI chr17:24,073,680...24,155,619
Ensembl chr17:24,073,680...24,150,924
JBrowse link
G Pdzk1ip1 PDZK1 interacting protein 1 increases expression ISO gemcitabine results in increased expression of PDZK1IP1 mRNA CTD PMID:17039268 NCBI chr 4:115,088,708...115,093,894
Ensembl chr 4:115,088,708...115,093,899
JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 multiple interactions EXP gemcitabine promotes the reaction [Curcumin results in decreased expression of PECAM1 protein] CTD PMID:17440100 NCBI chr11:106,654,213...106,715,281
Ensembl chr11:106,654,217...106,750,628
JBrowse link
G Pgr progesterone receptor multiple interactions ISO gemcitabine binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 9:8,898,900...8,968,611
Ensembl chr 9:8,899,833...8,968,611
JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 increases expression ISO gemcitabine results in increased expression of PJA2 mRNA CTD PMID:17039268 NCBI chr17:64,281,006...64,331,883
Ensembl chr17:64,281,005...64,331,916
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO gemcitabine results in increased expression of PLAU mRNA CTD PMID:17039268 NCBI chr14:20,836,662...20,843,388
Ensembl chr14:20,836,660...20,843,385
JBrowse link
G Plk1 polo like kinase 1 decreases expression
affects response to substance
multiple interactions
ISO gemcitabine results in decreased expression of PLK1; gemcitabine results in decreased expression of PLK1 mRNA
PLK1 protein affects the susceptibility to gemcitabine
[gemcitabine results in decreased expression of PLK1] which results in increased susceptibility to gemcitabine; ON 01910 promotes the reaction [PLK1 protein affects the susceptibility to gemcitabine]
CTD PMID:20103597 NCBI chr 7:122,159,435...122,169,884
Ensembl chr 7:122,159,439...122,169,873
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects expression EXP gemcitabine affects the expression of PPARA mRNA CTD PMID:19427843 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Ppard peroxisome proliferator activator receptor delta affects expression EXP gemcitabine affects the expression of PPARD mRNA CTD PMID:19427843 NCBI chr17:28,232,754...28,301,469
Ensembl chr17:28,232,700...28,301,474
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects expression EXP gemcitabine affects the expression of PPARG mRNA CTD PMID:19427843 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Ppfia4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 increases expression ISO gemcitabine results in increased expression of PPFIA4 mRNA CTD PMID:17039268 NCBI chr 1:134,296,783...134,344,756
Ensembl chr 1:134,296,783...134,332,928
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO gemcitabine results in increased expression of PPP1R15A mRNA CTD PMID:17039268 NCBI chr 7:45,522,917...45,526,268
Ensembl chr 7:45,522,916...45,526,268
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO gemcitabine results in increased expression of PSAT1 mRNA CTD PMID:17039268 NCBI chr19:15,905,123...15,925,059
Ensembl chr19:15,904,678...15,947,337
JBrowse link
G Ptch1 patched 1 affects expression ISO gemcitabine affects the expression of PTCH1 mRNA CTD PMID:20103597 NCBI chr13:63,508,328...63,573,460
Ensembl chr13:63,508,328...63,573,598
JBrowse link
G Pten phosphatase and tensin homolog affects expression ISO gemcitabine affects the expression of PTEN mRNA CTD PMID:17039268 NCBI chr19:32,757,577...32,826,160
Ensembl chr19:32,757,497...32,826,160
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO gemcitabine results in decreased expression of PTGS1 mRNA CTD PMID:17039268 NCBI chr 2:36,216,742...36,258,593
Ensembl chr 2:36,230,426...36,252,272
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Curcumin co-treated with gemcitabine] results in decreased expression of PTGS2 protein CTD PMID:17440100 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 decreases response to substance ISO PTK2 protein results in decreased susceptibility to gemcitabine CTD PMID:14623342 NCBI chr15:73,205,102...73,423,820
Ensembl chr15:73,205,102...73,423,280
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 affects expression ISO gemcitabine affects the expression of PTPN11 mRNA CTD PMID:17039268 NCBI chr 5:121,130,533...121,191,397
Ensembl chr 5:121,130,533...121,191,397
JBrowse link
G Rab8a RAB8A, member RAS oncogene family decreases expression ISO gemcitabine results in decreased expression of RAB8A mRNA CTD PMID:17039268 NCBI chr 8:72,161,200...72,181,366
Ensembl chr 8:72,161,200...72,183,904
JBrowse link
G Rbm17 RNA binding motif protein 17 decreases response to substance ISO RBM17 protein results in decreased susceptibility to gemcitabine CTD PMID:16061639 NCBI chr 2:11,585,439...11,603,199
Ensembl chr 2:11,585,437...11,604,153
JBrowse link
G Reg3b regenerating islet-derived 3 beta decreases expression ISO gemcitabine results in decreased expression of REG3A mRNA CTD PMID:16570353 NCBI chr 6:78,370,885...78,373,466
Ensembl chr 6:78,370,657...78,373,466
JBrowse link
G Rel reticuloendotheliosis oncogene multiple interactions
decreases expression
ISO sulforaphane promotes the reaction [gemcitabine results in decreased expression of REL protein] CTD PMID:20940707 NCBI chr11:23,736,847...23,770,969
Ensembl chr11:23,736,847...23,770,970
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
increases phosphorylation
increases expression
ISO
EXP
[gemcitabine co-treated with Doxorubicin co-treated with Paclitaxel] affects the localization of RELA protein; [gemcitabine co-treated with Doxorubicin co-treated with Paclitaxel] results in increased expression of RELA protein; licoricidin inhibits the reaction [gemcitabine results in increased phosphorylation of RELA protein]; Mastic Resin inhibits the reaction [gemcitabine results in increased expression of RELA protein]
[Curcumin co-treated with gemcitabine] results in decreased expression of RELA protein
CTD PMID:17039268 PMID:17440100 PMID:20523344 PMID:29782821 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO gemcitabine results in increased expression of RGS2 mRNA CTD PMID:17039268 NCBI chr 1:143,999,338...144,004,149
Ensembl chr 1:143,999,338...144,004,161
JBrowse link
G Rnf149 ring finger protein 149 increases expression ISO gemcitabine results in increased expression of RNF149 mRNA CTD PMID:17039268 NCBI chr 1:39,551,294...39,577,439
Ensembl chr 1:39,551,296...39,577,405
JBrowse link
G Rpl37 ribosomal protein L37 increases expression ISO gemcitabine results in increased expression of RPL37 mRNA CTD PMID:17039268 NCBI chr15:5,116,613...5,119,140
Ensembl chr15:5,116,645...5,119,140
JBrowse link
G Rragd Ras-related GTP binding D increases expression ISO gemcitabine results in increased expression of RRAGD mRNA CTD PMID:17039268 NCBI chr 4:32,982,998...33,022,180
Ensembl chr 4:32,983,037...33,022,180
JBrowse link
G Rrm1 ribonucleotide reductase M1 multiple interactions
affects response to substance
ISO [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of RRM1 mRNA; [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of RRM1 protein
RRM1 protein affects the susceptibility to gemcitabine
CTD PMID:25189999 PMID:26894857 NCBI chr 7:102,441,695...102,469,771
Ensembl chr 7:102,441,695...102,469,771
JBrowse link
G Rrm2 ribonucleotide reductase M2 multiple interactions
affects response to substance
decreases response to substance
ISO [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of RRM2 protein
RRM2 protein affects the susceptibility to gemcitabine
RRM2 protein results in decreased susceptibility to gemcitabine
CTD PMID:14661056 PMID:25189999 PMID:26894857 NCBI chr12:24,708,254...24,714,146
Ensembl chr12:24,708,241...24,714,146
JBrowse link
G Rsl24d1 ribosomal L24 domain containing 1 increases expression ISO gemcitabine results in increased expression of RSL24D1 mRNA CTD PMID:17039268 NCBI chr 9:73,113,469...73,123,333
Ensembl chr 9:73,113,426...73,123,333
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO gemcitabine results in increased expression of SAT1 mRNA CTD PMID:17039268 NCBI chr  X:155,213,126...155,216,449
Ensembl chr  X:155,213,132...155,216,449
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression ISO gemcitabine results in increased expression of SCD mRNA CTD PMID:17039268 NCBI chr19:44,293,676...44,306,864
Ensembl chr19:44,293,674...44,306,864
JBrowse link
G Sfn stratifin multiple interactions
affects response to substance
decreases response to substance
increases methylation
ISO [DNMT1 protein binds to SFN promoter] inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine]; [gemcitabine results in decreased susceptibility to gemcitabine] inhibits the reaction [DNMT1 protein binds to SFN promoter]; [gemcitabine results in decreased susceptibility to gemcitabine] which results in decreased methylation of SFN gene; [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of SFN mRNA; [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of SFN protein; [UHRF1 protein promotes the reaction [DNMT1 protein binds to SFN promoter]] inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine]; SFN protein affects the reaction [YAP1 protein promotes the reaction [SFN protein results in decreased susceptibility to gemcitabine]]; SFN protein inhibits the reaction [gemcitabine results in increased activity of and results in increased cleavage of CASP8 protein]; SFN protein inhibits the reaction [gemcitabine results in increased cleavage of PARP1 protein]; SFN protein promotes the reaction [gemcitabine results in decreased susceptibility to gemcitabine]; YAP1 protein promotes the reaction [SFN protein results in decreased susceptibility to gemcitabine]
SFN protein affects the susceptibility to gemcitabine
gemcitabine results in increased methylation of SFN gene
CTD PMID:25189999 PMID:26894857 NCBI chr 4:133,600,556...133,602,168
Ensembl chr 4:133,600,556...133,602,168
JBrowse link
G Shh sonic hedgehog decreases expression ISO gemcitabine results in decreased expression of SHH mRNA CTD PMID:20103597 NCBI chr 5:28,456,840...28,467,101
Ensembl chr 5:28,456,815...28,467,256
JBrowse link
G Slc25a29 solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29 increases expression ISO gemcitabine results in increased expression of SLC25A29 mRNA CTD PMID:17039268 NCBI chr12:108,825,878...108,835,876
Ensembl chr12:108,825,873...108,835,883
JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 multiple interactions ISO gemcitabine inhibits the reaction [SLC28A1 protein results in increased transport of Uridine]
gemcitabine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]
CTD PMID:8713072 PMID:10772724 NCBI chr 7:81,113,269...81,170,416
Ensembl chr 7:81,114,799...81,170,416
JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 multiple interactions
decreases response to substance
increases uptake
increases response to substance
affects response to substance
ISO 4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein results in increased uptake of gemcitabine]; [S 1 (combination) results in increased expression of SLC29A1 mRNA] which results in increased uptake of gemcitabine; Fluorouracil promotes the reaction [SLC29A1 protein results in increased uptake of gemcitabine]
SLC29A1 protein results in decreased susceptibility to gemcitabine
SLC29A1 mRNA results in increased susceptibility to gemcitabine; SLC29A1 protein results in increased susceptibility to gemcitabine
SLC29A1 protein affects the susceptibility to gemcitabine
CTD PMID:15501974 PMID:16868479 PMID:17695509 PMID:18383843 PMID:18452103 PMID:18490900 PMID:18728667 PMID:18992248 PMID:26894857 NCBI chr17:45,585,200...45,599,618
Ensembl chr17:45,585,200...45,599,606
JBrowse link
G Slc29a3 solute carrier family 29 (nucleoside transporters), member 3 affects transport ISO SLC29A3 protein affects the transport of gemcitabine CTD PMID:19164483 NCBI chr10:60,712,072...60,752,849
Ensembl chr10:60,712,072...60,752,794
JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 increases expression ISO gemcitabine results in increased expression of SLC2A3 mRNA CTD PMID:17039268 NCBI chr 6:122,727,809...122,802,363
Ensembl chr 6:122,727,809...122,801,640
JBrowse link
G Slc43a3 solute carrier family 43, member 3 decreases expression ISO gemcitabine results in decreased expression of SLC43A3 mRNA CTD PMID:17039268 NCBI chr 2:84,936,545...84,958,509
Ensembl chr 2:84,936,579...84,958,509
JBrowse link
G Slitrk2 SLIT and NTRK-like family, member 2 increases expression ISO gemcitabine results in increased expression of SLITRK2 mRNA CTD PMID:17039268 NCBI chr  X:66,648,951...66,661,402
Ensembl chr  X:66,649,318...66,661,393
JBrowse link
G Smg1 SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) multiple interactions
decreases response to substance
ISO SMG1 protein inhibits the reaction [gemcitabine results in increased activity of CASP3 protein]; SMG1 protein inhibits the reaction [gemcitabine results in increased activity of CASP9 protein]
SMG1 protein results in decreased susceptibility to gemcitabine
CTD PMID:21418860 NCBI chr 7:118,131,308...118,244,437
Ensembl chr 7:118,131,308...118,243,670
JBrowse link
G Smo smoothened, frizzled class receptor increases expression ISO gemcitabine results in increased expression of SMO mRNA CTD PMID:25605917 NCBI chr 6:29,735,497...29,761,366
Ensembl chr 6:29,735,503...29,761,365
JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 increases expression ISO gemcitabine results in increased expression of SOX2 mRNA CTD PMID:25605917 NCBI chr 3:34,649,995...34,652,461
Ensembl chr 3:34,650,405...34,652,461
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO gemcitabine results in increased expression of SPP1 mRNA CTD PMID:17039268 NCBI chr 5:104,435,111...104,441,053
Ensembl chr 5:104,435,118...104,441,050
JBrowse link
G Src Rous sarcoma oncogene multiple interactions
decreases response to substance
affects response to substance
ISO [AG 1879 co-treated with SRC] results in increased susceptibility to gemcitabine
SRC protein modified form results in decreased susceptibility to gemcitabine; SRC protein results in decreased susceptibility to gemcitabine
SRC protein affects the susceptibility to gemcitabine
CTD PMID:15073106 PMID:15194078 NCBI chr 2:157,423,906...157,471,838
Ensembl chr 2:157,418,444...157,471,862
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases activity ISO gemcitabine results in decreased activity of STAT3 protein CTD PMID:22348037 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein decreases expression ISO gemcitabine results in decreased expression of SYNCRIP mRNA CTD PMID:17039268 NCBI chr 9:88,449,364...88,482,591
Ensembl chr 9:88,447,009...88,482,574
JBrowse link
G Szrd1 SUZ RNA binding domain containing 1 decreases expression ISO gemcitabine results in decreased expression of SZRD1 mRNA CTD PMID:17039268 NCBI chr 4:141,112,978...141,139,799
Ensembl chr 4:141,113,001...141,139,775
JBrowse link
G Tceal9 transcription elongation factor A like 9 increases expression ISO gemcitabine results in increased expression of TCEAL9 mRNA CTD PMID:17039268 NCBI chr  X:136,245,080...136,247,139
Ensembl chr  X:136,245,079...136,247,139
JBrowse link
G Tcof1 treacle ribosome biogenesis factor 1 decreases expression ISO gemcitabine results in decreased expression of TCOF1 mRNA CTD PMID:17039268 NCBI chr18:60,813,738...60,848,983
Ensembl chr18:60,813,755...60,848,971
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions
decreases activity
ISO [Fluorouracil co-treated with gemcitabine] results in decreased activity of TERT protein
gemcitabine results in decreased activity of TERT protein
CTD PMID:16929163 NCBI chr13:73,626,911...73,649,843
Ensembl chr13:73,626,911...73,649,843
JBrowse link
G Tfap2a transcription factor AP-2, alpha multiple interactions
increases response to substance
ISO [TFAP2A protein co-treated with TP53 gene mutant form] results in decreased susceptibility to gemcitabine
TFAP2A protein results in increased susceptibility to gemcitabine
CTD PMID:21489314 NCBI chr13:40,713,802...40,738,238
Ensembl chr13:40,715,302...40,738,376
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases response to substance
multiple interactions
ISO TGFB1 results in decreased susceptibility to gemcitabine
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]; EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]; Erlotinib Hydrochloride inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]; pyrazolanthrone inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]; U 0126 inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]
CTD PMID:21613822 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO gemcitabine results in increased expression of TGFB2 mRNA CTD PMID:17039268 NCBI chr 1:186,622,787...186,709,697
Ensembl chr 1:186,622,792...186,705,989
JBrowse link
G Thpo thrombopoietin increases expression ISO gemcitabine results in increased expression of THPO protein CTD PMID:20531411 NCBI chr16:20,724,454...20,734,511
Ensembl chr16:20,724,454...20,734,511
JBrowse link
G Tnf tumor necrosis factor increases expression
affects expression
ISO gemcitabine results in increased expression of TNF protein
gemcitabine affects the expression of TNF mRNA
CTD PMID:17039268 PMID:20531411 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 increases expression ISO gemcitabine results in increased expression of TNFAIP3 mRNA CTD PMID:17039268 NCBI chr10:19,000,910...19,015,410
Ensembl chr10:19,000,910...19,015,657
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) increases expression ISO gemcitabine results in increased expression of TNFRSF11B mRNA CTD PMID:17039268 NCBI chr15:54,250,619...54,278,484
Ensembl chr15:54,250,619...54,278,484
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions ISO [TNFSF10 co-treated with gemcitabine] affects the localization of BAX protein; [TNFSF10 co-treated with gemcitabine] results in increased activity of CASP8 protein CTD PMID:17671697 NCBI chr 3:27,317,077...27,339,665
Ensembl chr 3:27,317,028...27,342,427
JBrowse link
G Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8 multiple interactions ISO [gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of TNFSF8 protein CTD PMID:24979617 NCBI chr 4:63,831,202...63,861,508
Ensembl chr 4:63,831,308...63,861,347
JBrowse link
G Traf1 TNF receptor-associated factor 1 affects expression ISO gemcitabine affects the expression of TRAF1 mRNA CTD PMID:17039268 NCBI chr 2:34,941,750...34,961,812
Ensembl chr 2:34,941,750...34,961,772
JBrowse link
G Trp53 transformation related protein 53 increases expression
multiple interactions
ISO gemcitabine results in increased expression of TP53 protein
[TFAP2A protein co-treated with TP53 gene mutant form] results in decreased susceptibility to gemcitabine; Nicotine inhibits the reaction [gemcitabine results in increased expression of TP53 protein]
CTD PMID:12082016 PMID:16601104 PMID:17671697 PMID:21489314 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 increases expression ISO gemcitabine results in increased expression of TP53BP1 mRNA CTD PMID:17039268 NCBI chr 2:121,194,835...121,296,354
Ensembl chr 2:121,193,281...121,271,407
JBrowse link
G Trp53inp1 transformation related protein 53 inducible nuclear protein 1 increases expression ISO gemcitabine results in increased expression of TP53INP1 mRNA CTD PMID:16570353 PMID:17039268 NCBI chr 4:11,156,441...11,174,379
Ensembl chr 4:11,156,431...11,174,379
JBrowse link
G Tube1 tubulin, epsilon 1 increases expression ISO gemcitabine results in increased expression of TUBE1 mRNA CTD PMID:17039268 NCBI chr10:39,133,949...39,151,058
Ensembl chr10:39,133,976...39,152,542
JBrowse link
G Tymp thymidine phosphorylase affects response to substance
multiple interactions
ISO TYMP protein affects the susceptibility to gemcitabine
[TYMP protein co-treated with DPYD protein] affects the susceptibility to gemcitabine; TYMP protein affects the susceptibility to [gemcitabine co-treated with Mitomycin]
CTD PMID:18728667 NCBI chr15:89,371,631...89,377,036
Ensembl chr15:89,371,931...89,377,039
JBrowse link
G Tyrp1 tyrosinase-related protein 1 affects expression ISO gemcitabine affects the expression of TYRP1 mRNA CTD PMID:17039268 NCBI chr 4:80,834,123...80,851,736
Ensembl chr 4:80,834,123...80,851,719
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression ISO gemcitabine results in decreased expression of UBE2C mRNA CTD PMID:17039268 NCBI chr 2:164,769,929...164,772,902
Ensembl chr 2:164,769,898...164,778,822
JBrowse link
G Uggt2 UDP-glucose glycoprotein glucosyltransferase 2 increases expression ISO gemcitabine results in increased expression of UGGT2 mRNA CTD PMID:17039268 NCBI chr14:118,982,006...119,099,796
Ensembl chr14:118,985,039...119,099,430
JBrowse link
G Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 multiple interactions ISO [gemcitabine results in decreased susceptibility to gemcitabine] which results in decreased expression of UHRF1 protein; [UHRF1 protein promotes the reaction [DNMT1 protein binds to SFN promoter]] inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine]; UHRF1 protein inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine] CTD PMID:25189999 NCBI chr17:56,303,337...56,323,486
Ensembl chr17:56,303,321...56,323,486
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO gemcitabine results in decreased expression of VCAM1 protein CTD PMID:20531411 NCBI chr 3:116,110,020...116,129,688
Ensembl chr 3:116,109,949...116,129,688
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions
ISO
EXP
gemcitabine results in increased expression of VEGFA mRNA
[Curcumin co-treated with gemcitabine] results in decreased expression of VEGFA protein
CTD PMID:17039268 PMID:17440100 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vgf VGF nerve growth factor inducible decreases expression ISO gemcitabine results in decreased expression of VGF mRNA CTD PMID:17039268 NCBI chr 5:137,025,301...137,033,351
Ensembl chr 5:137,026,392...137,033,351
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO gemcitabine results in increased expression of VLDLR mRNA CTD PMID:17039268 NCBI chr19:27,216,480...27,254,231
Ensembl chr19:27,216,484...27,254,231
JBrowse link
G Vmp1 vacuole membrane protein 1 increases expression ISO gemcitabine results in increased expression of VMP1 CTD PMID:20299819 NCBI chr11:86,583,858...86,683,836
Ensembl chr11:86,583,865...86,683,836
JBrowse link
G Vwf Von Willebrand factor decreases expression ISO gemcitabine results in decreased expression of VWF protein CTD PMID:20531411 NCBI chr 6:125,552,948...125,686,679
Ensembl chr 6:125,546,774...125,686,679
JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A decreases expression ISO gemcitabine results in decreased expression of WNT5A mRNA CTD PMID:17039268 NCBI chr14:28,504,543...28,527,448
Ensembl chr14:28,504,750...28,527,448
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO gemcitabine promotes the reaction [1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole results in increased expression of XBP1 mRNA]; gemcitabine promotes the reaction [arachidonylcyclopropylamide results in increased expression of XBP1 mRNA]; gemcitabine promotes the reaction [rimonabant results in increased expression of XBP1 mRNA] CTD PMID:21525939 NCBI chr11:5,520,641...5,525,993
Ensembl chr11:5,520,659...5,525,893
JBrowse link
G Xiap X-linked inhibitor of apoptosis affects response to substance ISO XIAP affects the susceptibility to gemcitabine CTD PMID:16628085 NCBI chr  X:42,059,613...42,109,664
Ensembl chr  X:42,059,679...42,109,656
JBrowse link
G Yap1 yes-associated protein 1 affects response to substance
multiple interactions
ISO YAP1 protein affects the susceptibility to gemcitabine
SFN protein affects the reaction [YAP1 protein promotes the reaction [SFN protein results in decreased susceptibility to gemcitabine]]; YAP1 protein affects the reaction [gemcitabine results in increased activity of and results in increased cleavage of CASP8 protein]; YAP1 protein affects the reaction [gemcitabine results in increased cleavage of PARP1 protein]; YAP1 protein promotes the reaction [SFN protein results in decreased susceptibility to gemcitabine]
CTD PMID:26894857 NCBI chr 9:7,931,999...8,004,638
Ensembl chr 9:7,931,999...8,004,596
JBrowse link
G Zfp110 zinc finger protein 110 increases expression ISO gemcitabine results in increased expression of ZNF274 mRNA CTD PMID:17039268 NCBI chr 7:12,834,761...12,850,586
Ensembl chr 7:12,834,761...12,850,577
JBrowse link
G Zfp449 zinc finger protein 449 increases expression ISO gemcitabine results in increased expression of ZNF449 mRNA CTD PMID:17039268 NCBI chr  X:56,346,397...56,365,674
Ensembl chr  X:56,346,400...56,365,674
JBrowse link
G Zfp521 zinc finger protein 521 decreases expression ISO gemcitabine results in decreased expression of ZNF521 mRNA CTD PMID:17039268 NCBI chr18:13,687,013...13,972,749
Ensembl chr18:13,687,013...13,972,787
JBrowse link
thymidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin, alpha 2, smooth muscle, aorta multiple interactions
increases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Thymidine results in increased expression of ACTA2 mRNA] CTD PMID:31170432 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Alpi alkaline phosphatase, intestinal multiple interactions ISO Thymidine promotes the reaction [Methotrexate results in increased activity of ALPI protein] CTD PMID:16598758 NCBI chr 1:87,098,002...87,101,606
Ensembl chr 1:87,098,002...87,101,606
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO Thymidine inhibits the reaction [Adenosine results in increased localization of BAX protein] CTD PMID:11570579 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO Thymidine inhibits the reaction [Adenosine results in increased activity of CASP3 protein]
Thymidine results in increased activity of CASP3 protein
CTD PMID:11570579 PMID:16419169 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Thymidine inhibits the reaction [Adenosine results in increased activity of CASP9 protein] CTD PMID:11570579 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) increases uptake ISO CSF1 protein results in increased uptake of Thymidine CTD PMID:8193360 NCBI chr 3:107,741,048...107,760,469
Ensembl chr 3:107,741,048...107,760,469
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) increases uptake EXP CSF2 protein results in increased uptake of Thymidine CTD PMID:8193360 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO [Thymidine co-treated with TYMP protein] results in increased secretion of CXCL8 protein; Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased secretion of CXCL8 protein] CTD PMID:11103787 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Edn1 endothelin 1 increases uptake ISO EDN1 protein results in increased uptake of Thymidine CTD PMID:10100047 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) increases expression ISO Thymidine results in increased expression of FASLG protein CTD PMID:16419169 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions ISO [Thymidine co-treated with TYMP co-treated with Oxygen deficiency] results in increased expression of HIF1A protein CTD PMID:15841086 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Thymidine co-treated with TYMP protein] results in increased expression of HMOX1 protein; [TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein]; Thymine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein] CTD PMID:11103787 PMID:15841086 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Igf1 insulin-like growth factor 1 decreases uptake
multiple interactions
ISO IGF1 protein results in decreased uptake of Thymidine
[Tetrachlorodibenzodioxin co-treated with Estradiol] inhibits the reaction [IGF1 protein results in increased uptake of Thymidine]; Tetrachlorodibenzodioxin inhibits the reaction [IGF1 protein results in decreased uptake of Thymidine]
CTD PMID:1332906 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) multiple interactions ISO [Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein; Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein] CTD PMID:11103787 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase multiple interactions ISO [Thymidine co-treated with Hypoxanthine co-treated with 5,6,7,8-tetrahydrofolic acid] inhibits the reaction [Methotrexate results in decreased expression of MTR protein]; [Thymidine co-treated with Hypoxanthine] inhibits the reaction [Methotrexate results in decreased expression of MTR protein] CTD PMID:16598758 NCBI chr13:12,181,331...12,258,199
Ensembl chr13:12,182,712...12,258,113
JBrowse link
G Myc myelocytomatosis oncogene multiple interactions ISO Thymidine inhibits the reaction [Adenosine results in decreased expression of MYC protein] CTD PMID:9808420 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 multiple interactions ISO Thymidine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine] CTD PMID:9124315 NCBI chr 7:81,113,269...81,170,416
Ensembl chr 7:81,114,799...81,170,416
JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 multiple interactions EXP
ISO
Thymidine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:9353301 PMID:11085929 NCBI chr17:45,585,200...45,599,618
Ensembl chr17:45,585,200...45,599,606
JBrowse link
G Slc29a2 solute carrier family 29 (nucleoside transporters), member 2 multiple interactions EXP Thymidine inhibits the reaction [SLC29A2 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr19:5,019,057...5,031,972
Ensembl chr19:5,023,860...5,031,972
JBrowse link
G Tymp thymidine phosphorylase multiple interactions
increases phosphorylation
ISO [Thymidine co-treated with TYMP co-treated with Oxygen deficiency] results in increased expression of HIF1A protein; [Thymidine co-treated with TYMP protein] results in increased expression of HMOX1 protein; [Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein; [Thymidine co-treated with TYMP protein] results in increased secretion of CXCL8 protein; [TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein]; Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein]; Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased secretion of CXCL8 protein]; Thymine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein]
TYMP protein results in increased phosphorylation of Thymidine
CTD PMID:11103787 PMID:15841086 NCBI chr15:89,371,631...89,377,036
Ensembl chr15:89,371,931...89,377,039
JBrowse link
G Tyms thymidylate synthase multiple interactions EXP Thymidine inhibits the reaction [Fluorouracil results in decreased expression of TYMS] CTD PMID:9050858 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
trifluridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO CA 074 methyl ester inhibits the reaction [Trifluridine results in increased cleavage of CASP3 protein]; Trifluridine results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:19816940 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp8 caspase 8 increases cleavage ISO Trifluridine results in increased cleavage of CASP8 protein CTD PMID:19816940 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Casp9 caspase 9 increases cleavage ISO Trifluridine results in increased cleavage of CASP9 protein CTD PMID:19816940 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Ctsb cathepsin B increases cleavage
multiple interactions
ISO Trifluridine results in increased cleavage of CTSB protein
CA 074 methyl ester inhibits the reaction [Trifluridine results in increased cleavage of CTSB protein]
CTD PMID:19816940 NCBI chr14:63,122,462...63,145,923
Ensembl chr14:63,122,462...63,145,923
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO Trifluridine inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:30818834 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO Trifluridine inhibits the reaction [XCT790 results in decreased activity of ESRRA protein] CTD PMID:30818834 NCBI chr19:6,910,977...6,922,048
Ensembl chr19:6,910,977...6,921,813
Ensembl chr19:6,910,977...6,921,813
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases activity ISO Trifluridine results in increased activity of NFE2L2 protein CTD PMID:30818834 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO Trifluridine results in increased activity of NR1I2 protein
[Trifluridine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
CTD PMID:25455453 NCBI chr16:38,248,349...38,294,849
Ensembl chr16:38,248,323...38,294,824
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO Trifluridine inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] CTD PMID:30818834 NCBI chr 1:171,213,934...171,218,845
Ensembl chr 1:171,213,970...171,220,701
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO Trifluridine results in increased cleavage of PARP1 protein CTD PMID:19816940 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
zalcitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 5730455P16Rik RIKEN cDNA 5730455P16 gene multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of RGD1310429 mRNA CTD PMID:18606552 NCBI chr11:80,360,492...80,378,048
Ensembl chr11:80,360,492...80,378,034
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 affects phosphorylation ISO Zalcitabine affects the phosphorylation of AKT1 protein CTD PMID:19781600 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Alb albumin affects binding ISO Zalcitabine binds to ALB protein CTD PMID:15814459 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Ano3 anoctamin 3 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ANO3 mRNA CTD PMID:18606552 NCBI chr 2:110,655,201...110,950,391
Ensembl chr 2:110,655,201...110,950,923
JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 increases response to substance ISO APEX1 protein mutant form results in increased susceptibility to Zalcitabine CTD PMID:17259346 NCBI chr14:50,924,949...50,927,188
Ensembl chr14:50,924,968...50,927,139
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of ARNT2 mRNA CTD PMID:18606552 NCBI chr 7:84,246,274...84,411,741
Ensembl chr 7:84,246,278...84,410,176
JBrowse link
G Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of ATP2B4 mRNA CTD PMID:18606552 NCBI chr 1:133,702,674...133,801,059
Ensembl chr 1:133,699,457...133,801,041
JBrowse link
G Bptf bromodomain PHD finger transcription factor multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of BPTF mRNA CTD PMID:18606552 NCBI chr11:107,033,081...107,132,147
Ensembl chr11:107,033,081...107,132,127
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 increases expression ISO Zalcitabine results in increased expression of CCL2 protein CTD PMID:17761732 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Cxcl12 chemokine (C-X-C motif) ligand 12 increases expression ISO Zalcitabine results in increased expression of CXCL12 mRNA CTD PMID:17292584 NCBI chr 6:117,168,535...117,181,368
Ensembl chr 6:117,168,535...117,181,367
JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 increases expression ISO Zalcitabine results in increased expression of CXCR4 mRNA CTD PMID:17292584 NCBI chr 1:128,588,199...128,592,299
Ensembl chr 1:128,588,199...128,592,293
JBrowse link
G Dck deoxycytidine kinase affects response to substance ISO DCK protein affects the susceptibility to Zalcitabine CTD PMID:11952160 NCBI chr 5:88,765,013...88,783,277
Ensembl chr 5:88,764,996...88,783,281
JBrowse link
G Depdc1b DEP domain containing 1B multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of DEPDC1B mRNA CTD PMID:18606552 NCBI chr13:108,316,014...108,389,566
Ensembl chr13:108,316,332...108,407,782
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of DLG5 mRNA CTD PMID:18606552 NCBI chr14:24,133,953...24,245,920
Ensembl chr14:24,133,953...24,245,920
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ESRRG mRNA CTD PMID:18606552 NCBI chr 1:187,608,510...188,214,885
Ensembl chr 1:187,608,791...188,214,885
JBrowse link
G Fam81a family with sequence similarity 81, member A multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of FAM81A mRNA CTD PMID:18606552 NCBI chr 9:70,089,304...70,142,558
Ensembl chr 9:70,088,511...70,142,560
JBrowse link
G Fpgt fucose-1-phosphate guanylyltransferase multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of FPGT mRNA CTD PMID:18606552 NCBI chr 3:155,084,915...155,093,387
Ensembl chr 3:155,084,918...155,093,403
JBrowse link
G Gla galactosidase, alpha multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of GLA mRNA CTD PMID:18606552 NCBI chr  X:134,588,169...134,601,005
Ensembl chr  X:134,588,149...134,601,125
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A increases response to substance
increases expression
multiple interactions
EXP
ISO
HTR2A gene results in increased susceptibility to Zalcitabine
Zalcitabine results in increased expression of HTR2A protein
[alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Zalcitabine
CTD PMID:17888573 NCBI chr14:74,640,874...74,706,859
Ensembl chr14:74,640,840...74,709,494
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain decreases expression
multiple interactions
ISO Zalcitabine results in decreased expression of IL2RA mRNA; Zalcitabine results in decreased expression of IL2RA protein
Zidovudine promotes the reaction [Zalcitabine results in decreased expression of IL2RA mRNA]; Zidovudine promotes the reaction [Zalcitabine results in decreased expression of IL2RA protein]
CTD PMID:7606800 NCBI chr 2:11,642,792...11,693,194
Ensembl chr 2:11,642,807...11,693,193
JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of IRF7 mRNA CTD PMID:18606552 NCBI chr 7:141,263,183...141,266,499
Ensembl chr 7:141,262,706...141,266,481
JBrowse link
G Kif5a kinesin family member 5A multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of KIF5A mRNA CTD PMID:18606552 NCBI chr10:127,225,695...127,266,348
Ensembl chr10:127,225,696...127,263,348
JBrowse link
G Lama5 laminin, alpha 5 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of LAMA5 mRNA CTD PMID:18606552 NCBI chr 2:180,176,373...180,225,904
Ensembl chr 2:180,176,373...180,225,859
JBrowse link
G Luzp2 leucine zipper protein 2 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of LUZP2 mRNA CTD PMID:18606552 NCBI chr 7:54,835,245...55,268,888
Ensembl chr 7:54,835,498...55,268,885
JBrowse link
G Midn midnolin multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of MIDN mRNA CTD PMID:18606552 NCBI chr10:80,146,005...80,158,368
Ensembl chr10:80,148,272...80,158,368
JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial decreases expression
multiple interactions
ISO
EXP
Zalcitabine results in decreased expression of COX1 protein
Uridine inhibits the reaction [Zalcitabine results in decreased expression of COX1 protein]
CTD PMID:17187420 PMID:18823003 PMID:20032772 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
JBrowse link
G mt-Co2 cytochrome c oxidase II, mitochondrial decreases expression ISO Zalcitabine results in decreased expression of COX2 mRNA CTD PMID:19781600 NCBI chr MT:7,013...7,696
Ensembl chr MT:7,013...7,696
JBrowse link
G mt-Co3 cytochrome c oxidase III, mitochondrial decreases expression ISO Zalcitabine results in decreased expression of COX3 protein CTD PMID:17508937 NCBI chr MT:8,607...9,390
Ensembl chr MT:8,607...9,390
JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 multiple interactions ISO Zalcitabine inhibits the reaction [Cyclic AMP results in increased phosphorylation of NDUFB11 protein] CTD PMID:17904600 NCBI chr  X:20,615,326...20,617,619
Ensembl chr  X:20,615,326...20,617,619
JBrowse link
G Necab1 N-terminal EF-hand calcium binding protein 1 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of NECAB1 mRNA CTD PMID:18606552 NCBI chr 4:14,952,245...15,149,804
Ensembl chr 4:14,952,245...15,149,794
JBrowse link
G Nkiras1 NFKB inhibitor interacting Ras-like protein 1 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of NKIRAS1 mRNA CTD PMID:18606552 NCBI chr14:18,271,136...18,284,003
Ensembl chr14:18,271,136...18,284,003
JBrowse link
G Notch1 notch 1 increases mutagenesis EXP Zalcitabine results in increased mutagenesis of NOTCH1 gene CTD PMID:18798262 NCBI chr 2:26,457,902...26,503,822
Ensembl chr 2:26,457,903...26,516,663
JBrowse link
G Npy neuropeptide Y multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of NPY mRNA CTD PMID:18606552 NCBI chr 6:49,822,710...49,829,507
Ensembl chr 6:49,822,710...49,829,507
JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of NTRK2 mRNA alternative form CTD PMID:18606552 NCBI chr13:58,806,472...59,133,970
Ensembl chr13:58,806,569...59,133,970
JBrowse link
G Per2 period circadian clock 2 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of PER2 mRNA CTD PMID:18606552 NCBI chr 1:91,415,977...91,459,351
Ensembl chr 1:91,415,982...91,459,324
JBrowse link
G Rab27b RAB27B, member RAS oncogene family multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of RAB27B mRNA CTD PMID:18606552 NCBI chr18:69,979,131...70,141,633
Ensembl chr18:69,979,131...70,141,605
JBrowse link
G Reg3b regenerating islet-derived 3 beta multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of REG3B mRNA; [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of REG3B protein CTD PMID:18606552 NCBI chr 6:78,370,885...78,373,466
Ensembl chr 6:78,370,657...78,373,466
JBrowse link
G Robo2 roundabout guidance receptor 2 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ROBO2 mRNA CTD PMID:18606552 NCBI chr16:73,891,976...75,447,443
Ensembl chr16:73,891,839...74,411,825
JBrowse link
G Scube1 signal peptide, CUB domain, EGF-like 1 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of SCUBE1 mRNA CTD PMID:18606552 NCBI chr15:83,602,583...83,725,051
Ensembl chr15:83,604,999...83,725,021
JBrowse link
G Senp5 SUMO/sentrin specific peptidase 5 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of SENP5 mRNA CTD PMID:18606552 NCBI chr16:31,959,670...32,003,287
Ensembl chr16:31,959,672...32,003,287
JBrowse link
G Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 multiple interactions
increases uptake
ISO Zalcitabine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]; Zalcitabine promotes the reaction [SLC28A1 protein results in increased export of Uridine]
SLC28A1 protein results in increased uptake of Zalcitabine
CTD PMID:8027026 PMID:8700147 PMID:8713072 NCBI chr 7:81,113,269...81,170,416
Ensembl chr 7:81,114,799...81,170,416
JBrowse link
G Slc29a3 solute carrier family 29 (nucleoside transporters), member 3 affects transport ISO SLC29A3 protein affects the transport of Zalcitabine CTD PMID:19164483 NCBI chr10:60,712,072...60,752,849
Ensembl chr10:60,712,072...60,752,794
JBrowse link
G Slc35g2 solute carrier family 35, member G2 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of SLC35G2 mRNA CTD PMID:18606552 NCBI chr 9:100,549,125...100,571,085
Ensembl chr 9:100,552,188...100,571,090
JBrowse link
G Slc4a8 solute carrier family 4 (anion exchanger), member 8 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of SLC4A8 mRNA CTD PMID:18606552 NCBI chr15:100,761,747...100,823,971
Ensembl chr15:100,761,747...100,823,968
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ST8SIA3 mRNA CTD PMID:18606552 NCBI chr18:64,254,359...64,276,146
Ensembl chr18:64,254,359...64,279,611
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2 b multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of SV2B mRNA CTD PMID:18606552 NCBI chr 7:75,114,894...75,309,262
Ensembl chr 7:75,114,894...75,309,262
JBrowse link
G Tfam transcription factor A, mitochondrial affects expression ISO Zalcitabine affects the expression of TFAM protein CTD PMID:7849699 NCBI chr10:71,225,468...71,238,328
Ensembl chr10:71,225,464...71,238,280
JBrowse link
G Tk1 thymidine kinase 1 decreases expression ISO Zalcitabine results in decreased expression of TK1 mRNA; Zalcitabine results in decreased expression of TK1 protein CTD PMID:14659972 NCBI chr11:117,815,519...117,826,087
Ensembl chr11:117,815,526...117,826,092
JBrowse link
G Tk2 thymidine kinase 2, mitochondrial decreases expression ISO Zalcitabine results in decreased expression of TK2 mRNA CTD PMID:14659972 NCBI chr 8:104,226,691...104,248,592
Ensembl chr 8:104,226,685...104,248,558
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases response to substance ISO TRPV4 protein results in increased susceptibility to Zalcitabine CTD PMID:18234883 NCBI chr 5:114,622,152...114,658,435
Ensembl chr 5:114,622,152...114,658,421
JBrowse link
G Tymp thymidine phosphorylase increases expression ISO Zalcitabine results in increased expression of TYMP protein CTD PMID:16457948 NCBI chr15:89,371,631...89,377,036
Ensembl chr15:89,371,931...89,377,039
JBrowse link
G Vgf VGF nerve growth factor inducible multiple interactions ISO [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of VGF mRNA CTD PMID:18606552 NCBI chr 5:137,025,301...137,033,351
Ensembl chr 5:137,026,392...137,033,351
JBrowse link
zidovudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700007K13Rik RIKEN cDNA 1700007K13 gene multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of C9ORF116 mRNA CTD PMID:20370541 NCBI chr 2:28,462,001...28,466,324
Ensembl chr 2:28,462,001...28,466,332
JBrowse link
G Abca3 ATP-binding cassette, sub-family A (ABC1), member 3 increases expression ISO Zidovudine results in increased expression of ABCA3 mRNA CTD PMID:24292225 NCBI chr17:24,351,921...24,410,204
Ensembl chr17:24,351,950...24,410,201
JBrowse link
G Abca7 ATP-binding cassette, sub-family A (ABC1), member 7 decreases expression
increases expression
ISO Zidovudine results in decreased expression of ABCA7 mRNA
Zidovudine results in increased expression of ABCA7 mRNA
CTD PMID:24292225 NCBI chr10:79,996,453...80,015,572
Ensembl chr10:79,996,494...80,015,572
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 decreases expression ISO Zidovudine results in decreased expression of ABCB11 mRNA CTD PMID:27765674 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A increases expression ISO Zidovudine results in increased expression of ABCB1 mRNA; Zidovudine results in increased expression of ABCB1 protein CTD PMID:9148857 PMID:15456083 PMID:18310046 PMID:24292225 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Abcb9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 increases expression ISO Zidovudine results in increased expression of ABCB9 mRNA CTD PMID:24292225 NCBI chr 5:124,061,857...124,095,955
Ensembl chr 5:124,061,530...124,095,798
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 increases expression ISO Zidovudine results in increased expression of ABCC1 mRNA CTD PMID:24292225 NCBI chr16:14,361,453...14,474,878
Ensembl chr16:14,361,558...14,475,737
JBrowse link
G Abcc10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 increases expression ISO Zidovudine results in increased expression of ABCC10 mRNA CTD PMID:24292225 NCBI chr17:46,303,220...46,328,031
Ensembl chr17:46,303,221...46,328,352
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 increases expression
decreases expression
ISO Zidovudine results in increased expression of ABCC3 mRNA
Zidovudine results in decreased expression of ABCC3 mRNA
CTD PMID:24292225 PMID:27765674 NCBI chr11:94,343,295...94,393,017
Ensembl chr11:94,343,295...94,392,997
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 affects abundance
increases expression
increases export
ISO ABCC4 protein affects the abundance of Zidovudine
Zidovudine results in increased expression of ABCC4 mRNA
ABCC4 protein results in increased export of Zidovudine
CTD PMID:15456083 PMID:18364470 PMID:18535159 NCBI chr14:118,482,692...118,707,856
Ensembl chr14:118,482,692...118,706,219
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 increases export
increases expression
ISO ABCC5 protein results in increased export of Zidovudine
Zidovudine results in increased expression of ABCC5 mRNA
CTD PMID:15456083 PMID:18535159 PMID:24292225 NCBI chr16:20,331,303...20,426,428
Ensembl chr16:20,331,303...20,426,394
JBrowse link
G Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 increases expression ISO Zidovudine results in increased expression of ABCC6 mRNA CTD PMID:24292225 NCBI chr 7:45,974,110...46,030,491
Ensembl chr 7:45,967,555...46,030,302
JBrowse link
G Abcd1 ATP-binding cassette, sub-family D (ALD), member 1 increases expression ISO Zidovudine results in increased expression of ABCD1 mRNA CTD PMID:24292225 NCBI chr  X:73,716,597...73,738,534
Ensembl chr  X:73,716,597...73,738,534
JBrowse link
G Abcf2 ATP-binding cassette, sub-family F (GCN20), member 2 increases expression ISO Zidovudine results in increased expression of ABCF2 mRNA CTD PMID:24292225 NCBI chr 5:24,565,341...24,577,467
Ensembl chr 5:24,565,345...24,577,467
JBrowse link
G Abcf3 ATP-binding cassette, sub-family F (GCN20), member 3 increases expression ISO Zidovudine results in increased expression of ABCF3 mRNA CTD PMID:24292225 NCBI chr16:20,548,556...20,561,603
Ensembl chr16:20,548,577...20,561,379
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions
increases expression
decreases expression
increases export
decreases export
EXP
ISO
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]; 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]; Elacridar inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]; Elacridar inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]; Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]; pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]
Zidovudine results in increased expression of ABCG2 protein
Zidovudine results in decreased expression of ABCG2 mRNA
Zidovudine results in increased expression of ABCG2 mRNA
CTD PMID:17437964 PMID:19056916 PMID:24292225 PMID:27765674 PMID:28705594 NCBI chr 6:58,584,491...58,692,451
Ensembl chr 6:58,584,523...58,695,676
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression ISO Zidovudine results in decreased expression of ABCG8 mRNA CTD PMID:27765674 NCBI chr17:84,676,302...84,700,333
Ensembl chr17:84,676,302...84,700,333
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha affects expression ISO Zidovudine affects the expression of ACACA mRNA CTD PMID:20032539 NCBI chr11:84,129,635...84,401,651
Ensembl chr11:84,129,672...84,401,651
JBrowse link
G Acacb acetyl-Coenzyme A carboxylase beta affects expression ISO Zidovudine affects the expression of ACACB mRNA CTD PMID:20032539 NCBI chr 5:114,146,321...114,250,761
Ensembl chr 5:114,146,535...114,250,761
JBrowse link
G Acadsb acyl-Coenzyme A dehydrogenase, short/branched chain multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of ACADSB mRNA CTD PMID:18313992 NCBI chr 7:131,410,601...131,446,211
Ensembl chr 7:131,410,601...131,448,944
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in decreased expression of ACSL6 mRNA CTD PMID:18313992 NCBI chr11:54,303,805...54,364,756
Ensembl chr11:54,303,798...54,364,756
JBrowse link
G Ada adenosine deaminase increases expression ISO Zidovudine results in increased expression of ADA protein CTD PMID:2261134 NCBI chr 2:163,726,571...163,750,239
Ensembl chr 2:163,726,584...163,750,239
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
multiple interactions
ISO
EXP
Zidovudine results in decreased expression of ADIPOQ protein
Zidovudine results in decreased expression of ADIPOQ mRNA; Zidovudine results in decreased expression of ADIPOQ protein
[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ADIPOQ mRNA
CTD PMID:15865214 PMID:16931933 PMID:17503663 PMID:17668557 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of AEBP1 mRNA CTD PMID:16931933 NCBI chr11:5,861,866...5,872,248
Ensembl chr11:5,861,947...5,872,088
JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of AFAP1 mRNA CTD PMID:15784690 NCBI chr 5:35,893,319...36,003,923
Ensembl chr 5:35,893,319...36,003,923
JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 increases expression
multiple interactions
ISO Zidovudine results in increased expression of AGPAT3 mRNA
[Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA; silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA]
CTD PMID:28619387 NCBI chr10:78,269,174...78,352,497
Ensembl chr10:78,269,178...78,352,489
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation ISO Zidovudine results in increased phosphorylation of AKT1 protein CTD PMID:29594326 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Alb albumin affects binding ISO Zidovudine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ALOX5AP mRNA CTD PMID:16931933 NCBI chr 5:149,265,004...149,288,153
Ensembl chr 5:149,264,767...149,288,153
JBrowse link
G Apoa5 apolipoprotein A-V decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of APOA5 mRNA
[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA; silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA]
CTD PMID:28619387 NCBI chr 9:46,268,608...46,271,921
Ensembl chr 9:46,268,633...46,271,919
JBrowse link
G Aprt adenine phosphoribosyl transferase increases mutagenesis ISO Zidovudine results in increased mutagenesis of APRT gene CTD PMID:10970446 NCBI chr 8:122,574,637...122,576,907
Ensembl chr 8:122,574,635...122,576,909
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO
EXP
[Zidovudine co-treated with IFNA1 protein] results in increased expression of AQP9 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of AQP9 mRNA
CTD PMID:18313992 PMID:20370541 NCBI chr 9:71,110,659...71,167,849
Ensembl chr 9:71,110,659...71,168,682
JBrowse link
G Arpp21 cyclic AMP-regulated phosphoprotein, 21 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ARPP21 mRNA CTD PMID:16931933 NCBI chr 9:112,065,091...112,236,288
Ensembl chr 9:112,065,091...112,235,938
JBrowse link
G Asic2 acid-sensing (proton-gated) ion channel 2 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ASIC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ASIC2 mRNA CTD PMID:16931933 NCBI chr11:80,880,163...81,968,396
Ensembl chr11:80,880,169...81,968,457
JBrowse link
G Asl argininosuccinate lyase increases activity
multiple interactions
ISO Zidovudine results in increased activity of ASL protein
[Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein; silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein]
CTD PMID:28619387 NCBI chr 5:130,011,258...130,024,381
Ensembl chr 5:130,011,258...130,029,247
JBrowse link
G Asns asparagine synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASNS mRNA CTD PMID:15784690 NCBI chr 6:7,675,165...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Ass1 argininosuccinate synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASS1 mRNA CTD PMID:15784690 NCBI chr 2:31,470,270...31,520,670
Ensembl chr 2:31,470,207...31,520,672
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATF3 mRNA CTD PMID:15784690 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ATP2A2 mRNA CTD PMID:11706060 NCBI chr 5:122,453,513...122,502,225
Ensembl chr 5:122,453,513...122,502,225
JBrowse link
G Atp5c1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5C1 mRNA CTD PMID:18313992 NCBI chr 2:10,056,030...10,080,510
Ensembl chr 2:10,056,016...10,080,510
JBrowse link
G Atp5d ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit decreases expression ISO Zidovudine results in decreased expression of ATP5F1D mRNA CTD PMID:16894629 NCBI chr10:80,138,698...80,145,828
Ensembl chr10:80,138,632...80,145,818
JBrowse link
G Atp5g3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) increases expression
multiple interactions
ISO
EXP
Zidovudine results in increased expression of ATP5MC3 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5G3 mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr 2:73,908,447...73,912,464
Ensembl chr 2:73,908,447...73,911,326
JBrowse link
G Atp5h ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5H mRNA CTD PMID:18313992 NCBI chr11:115,415,691...115,419,919
Ensembl chr11:115,415,689...115,419,962
JBrowse link
G Atp5j ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F increases expression
multiple interactions
ISO
EXP
Zidovudine results in increased expression of ATP5PF mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr16:84,827,871...84,835,857
Ensembl chr16:84,827,866...84,835,625
JBrowse link
G Atp5j2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J2 mRNA CTD PMID:18313992 NCBI chr 5:145,183,704...145,191,541
Ensembl chr 5:145,183,698...145,192,062
JBrowse link
G Atp5k ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit E increases expression ISO Zidovudine results in increased expression of ATP5ME mRNA CTD PMID:16894629 NCBI chr 5:108,433,246...108,434,399
Ensembl chr 5:108,433,244...108,434,448
JBrowse link
G Atp5l ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G increases expression ISO Zidovudine results in increased expression of ATP5MG mRNA CTD PMID:16894629 NCBI chr 9:44,913,248...44,920,742
Ensembl chr 9:44,912,557...44,920,742
JBrowse link
G Atp5o ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit increases expression
multiple interactions
ISO
EXP
Zidovudine results in increased expression of ATP5PO mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5O mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr16:91,925,223...91,931,630
Ensembl chr16:91,925,214...91,931,687
Ensembl chr16:91,925,214...91,931,687
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b increases expression ISO Zidovudine results in increased expression of ATP5PB mRNA CTD PMID:16894629 NCBI chr 3:105,942,698...105,959,263
Ensembl chr 3:105,942,698...105,960,099
JBrowse link
G Atp8b1 ATPase, class I, type 8B, member 1 decreases expression ISO Zidovudine results in decreased expression of ATP8B1 mRNA CTD PMID:16894629 NCBI chr18:64,528,979...64,661,272
Ensembl chr18:64,528,967...64,661,267
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 affects response to substance
increases expression
multiple interactions
decreases expression
ISO
EXP
BCL2 protein affects the susceptibility to Zidovudine
Zidovudine results in increased expression of BCL2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of BCL2 mRNA
Drugs, Chinese Herbal promotes the reaction [Zidovudine results in decreased expression of BCL2 mRNA]
CTD PMID:9850737 PMID:17696246 PMID:18313992 PMID:29594326 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like increases expression ISO Zidovudine results in increased expression of BNIP3L protein CTD PMID:23640862 NCBI chr14:66,985,238...67,008,877
Ensembl chr14:66,985,239...67,008,877
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of BST2 mRNA CTD PMID:20370541 NCBI chr 8:71,534,255...71,537,472
Ensembl chr 8:71,534,255...71,537,456
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Zidovudine results in increased expression of BTG2 mRNA CTD PMID:23675285 NCBI chr 1:134,074,865...134,079,155
Ensembl chr 1:134,075,170...134,079,120
JBrowse link
G C1rb complement component 1, r subcomponent B multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C1R mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C1R mRNA CTD PMID:16931933 NCBI chr 6:124,570,430...124,581,044
Ensembl chr 6:124,570,294...124,581,171
JBrowse link
G C3ar1 complement component 3a receptor 1 multiple interactions ISO
EXP
[Zidovudine co-treated with IFNA1 protein] results in increased expression of C3AR1 mRNA
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of C3AR1 mRNA
CTD PMID:16931933 PMID:20370541 NCBI chr 6:122,847,140...122,856,157
Ensembl chr 6:122,847,138...122,856,161
JBrowse link
G Cars cysteinyl-tRNA synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CARS1 mRNA CTD PMID:15784690 NCBI chr 7:143,557,230...143,600,090
Ensembl chr 7:143,557,230...143,600,090
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity
ISO
EXP
[Acrolein co-treated with Zidovudine] results in increased cleavage of CASP3 protein; Drugs, Chinese Herbal promotes the reaction [Zidovudine results in increased expression of CASP3 mRNA]
Zidovudine results in increased cleavage of CASP3 protein
Zidovudine results in increased expression of CASP3 protein
Zidovudine results in increased activity of CASP3 protein
2,6-dimethyl-3,5-bis(2'-propoxyethoxycarbonyl)-4-(2''-difluoromethoxyphenyl)-1,4-dihydropyridine inhibits the reaction [Zidovudine results in increased expression of CASP3 protein]; glutapyrone inhibits the reaction [Zidovudine results in increased expression of CASP3 protein]; tauropyrone inhibits the reaction [Zidovudine results in increased expression of CASP3 protein]
CTD PMID:16601281 PMID:17696246 PMID:17943461 PMID:18801031 PMID:27238871 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions
ISO Zidovudine results in increased cleavage of CASP8 protein
Acrolein promotes the reaction [Zidovudine results in increased cleavage of CASP8 protein]; Zidovudine promotes the reaction [Acrolein results in increased cleavage of CASP8 protein]
CTD PMID:27238871 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Cat catalase decreases response to substance EXP CAT protein results in decreased susceptibility to Zidovudine CTD PMID:19398959 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 increases expression ISO Zidovudine results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNA2 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNA2 mRNA
Zidovudine results in decreased expression of CCNA2 mRNA
CTD PMID:15784690 PMID:20370541 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNB1 mRNA CTD PMID:20370541 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Ccnc cyclin C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNC mRNA CTD PMID:15784690 NCBI chr 4:21,727,701...21,759,922
Ensembl chr 4:21,727,701...21,759,922
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CCND1 mRNA
Zidovudine results in increased expression of CCND1 mRNA
CTD PMID:15784690 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G Ccnd2 cyclin D2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCND2 mRNA
Zidovudine results in decreased expression of CCND2 mRNA
CTD PMID:15784690 NCBI chr 6:127,125,162...127,152,188
Ensembl chr 6:127,125,162...127,152,193
JBrowse link
G Ccne2 cyclin E2 decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of CCNE2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CCNE2 mRNA
CTD PMID:15784690 NCBI chr 4:11,190,433...11,204,779
Ensembl chr 4:11,191,351...11,204,779
JBrowse link
G Ccnl2 cyclin L2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNL2 mRNA CTD PMID:20370541 NCBI chr 4:155,810,219...155,824,543
Ensembl chr 4:155,812,489...155,824,543
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCR5 mRNA CTD PMID:20370541 NCBI chr 9:124,121,543...124,127,183
Ensembl chr 9:124,121,543...124,147,699
JBrowse link
G Cd36 CD36 molecule multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CD36 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CD36 mRNA CTD PMID:16931933 NCBI chr 5:17,781,690...17,888,959
Ensembl chr 5:17,781,690...17,888,801
JBrowse link
G Cd44 CD44 antigen multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CD44 mRNA CTD PMID:15784690 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665
JBrowse link
G Cd83 CD83 antigen multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CD83 mRNA CTD PMID:15784690 NCBI chr13:43,785,112...43,803,133
Ensembl chr13:43,784,775...43,803,132
JBrowse link
G Cdc25a cell division cycle 25A multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CDC25A mRNA CTD PMID:20370541 NCBI chr 9:109,875,518...109,893,895
Ensembl chr 9:109,875,579...109,893,895
JBrowse link
G Cdca8 cell division cycle associated 8 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of CDCA8 mRNA CTD PMID:20370541 NCBI chr 4:124,918,465...124,936,917
Ensembl chr 4:124,918,465...124,939,311
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CDK1 mRNA CTD PMID:20370541 NCBI chr10:69,335,146...69,352,912
Ensembl chr10:69,335,146...69,352,938
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CDK4 mRNA CTD PMID:20370541 NCBI chr10:127,063,535...127,067,288
Ensembl chr10:127,063,534...127,067,920
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of CDK6 mRNA CTD PMID:20370541 NCBI chr 5:3,341,004...3,531,008
Ensembl chr 5:3,341,485...3,531,008
JBrowse link
G Cdk7 cyclin-dependent kinase 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CDK7 mRNA CTD PMID:15784690 NCBI chr13:100,697,024...100,730,942
Ensembl chr13:100,702,631...100,730,939
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions
affects expression
decreases expression
ISO
EXP
[Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1A mRNA
Zidovudine affects the expression of CDKN1A protein
Zidovudine results in decreased expression of CDKN1A mRNA
CTD PMID:15784690 PMID:18389896 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1B mRNA CTD PMID:15784690 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1C mRNA CTD PMID:15784690 NCBI chr 7:143,458,339...143,461,059
Ensembl chr 7:143,458,339...143,461,050
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A increases expression
affects expression
ISO
EXP
Zidovudine results in increased expression of CDKN2A mRNA; Zidovudine results in increased expression of CDKN2A protein
Zidovudine affects the expression of CDKN2A protein
CTD PMID:16797627 PMID:18389896 NCBI chr 4:89,274,473...89,294,619
Ensembl chr 4:89,274,471...89,294,653
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN2C mRNA CTD PMID:15784690 NCBI chr 4:109,660,876...109,666,756
Ensembl chr 4:109,660,876...109,667,189
JBrowse link
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha decreases expression EXP Zidovudine results in decreased expression of CEBPA protein CTD PMID:15722030 NCBI chr 7:35,119,293...35,121,928
Ensembl chr 7:35,119,293...35,121,928
JBrowse link
G Cfd complement factor D (adipsin) multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CFD mRNA CTD PMID:16931933 NCBI chr10:79,890,853...79,892,655
Ensembl chr10:79,890,853...79,892,655
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation
decreases expression
ISO Zidovudine results in increased phosphorylation of CHEK1 protein
Zidovudine results in decreased expression of CHEK1 protein
CTD PMID:19541796 NCBI chr 9:36,708,482...36,726,658
Ensembl chr 9:36,708,482...36,727,065
JBrowse link
G Chek2 checkpoint kinase 2 decreases expression
increases phosphorylation
ISO Zidovudine results in decreased expression of CHEK2 protein
Zidovudine results in increased phosphorylation of CHEK2 protein
CTD PMID:19541796 NCBI chr 5:110,839,800...110,874,140
Ensembl chr 5:110,839,979...110,874,145
JBrowse link
G Chn1 chimerin 1 decreases expression ISO Zidovudine results in decreased expression of CHN1 mRNA CTD PMID:16894629 NCBI chr 2:73,610,660...73,775,367
Ensembl chr 2:73,610,660...73,775,346
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CIDEC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CIDEC mRNA CTD PMID:16931933 NCBI chr 6:113,424,634...113,435,760
Ensembl chr 6:113,424,634...113,435,760
JBrowse link
G Clcn3 chloride channel, voltage-sensitive 3 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of CLCN3 mRNA CTD PMID:16931933 NCBI chr 8:60,910,389...60,983,317
Ensembl chr 8:60,910,389...60,983,300
JBrowse link
G Clec2i C-type lectin domain family 2, member i multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of CLEC2I mRNA CTD PMID:16931933 NCBI chr 6:128,887,587...128,898,168
Ensembl chr 6:128,887,588...128,898,167
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COMT mRNA CTD PMID:15784690 NCBI chr16:18,406,882...18,426,716
Ensembl chr16:18,406,886...18,426,852
JBrowse link
G Cox11 cytochrome c oxidase assembly protein 11, copper chaperone decreases expression ISO Zidovudine results in decreased expression of COX11 mRNA CTD PMID:16894629 NCBI chr11:90,638,184...90,645,977
Ensembl chr11:90,638,173...90,644,931
JBrowse link
G Cox15 cytochrome c oxidase assembly protein 15 decreases expression ISO Zidovudine results in decreased expression of COX15 mRNA CTD PMID:16894629 NCBI chr19:43,733,254...43,753,000
Ensembl chr19:43,733,254...43,753,000
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression
multiple interactions
ISO
EXP
Zidovudine results in decreased expression of COX5A protein
[Zidovudine co-treated with Lamivudine] results in decreased expression of COX5A mRNA
CTD PMID:7807166 PMID:18313992 NCBI chr 9:57,517,328...57,532,427
Ensembl chr 9:57,521,274...57,532,426
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions
decreases expression
EXP
ISO
[Zidovudine co-treated with Lamivudine] results in increased expression of COX5B mRNA
Zidovudine results in decreased expression of COX5B protein
CTD PMID:7807166 PMID:18313992 NCBI chr 1:36,691,487...36,693,388
Ensembl chr 1:36,691,449...36,693,681
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of COX6A1 mRNA CTD PMID:18313992 NCBI chr 5:115,345,652...115,348,958
Ensembl chr 5:115,345,642...115,348,981
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C decreases expression
multiple interactions
ISO
EXP
Zidovudine results in decreased expression of COX6C protein
[Zidovudine co-treated with Lamivudine] results in increased expression of COX6C mRNA
CTD PMID:7807166 PMID:18313992 NCBI chr15:35,931,976...35,938,246
Ensembl chr15:35,925,886...35,938,246
JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 decreases expression ISO Zidovudine results in decreased expression of COX7A1 protein CTD PMID:7807166 NCBI chr 7:30,184,171...30,186,030
Ensembl chr 7:30,184,144...30,186,078
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 increases expression ISO Zidovudine results in increased expression of COX7A2 mRNA CTD PMID:16894629 NCBI chr 9:79,755,241...79,771,422
Ensembl chr 9:79,755,361...79,759,878
JBrowse link
G Cox7b cytochrome c oxidase subunit 7B increases expression
decreases expression
ISO Zidovudine results in increased expression of COX7B mRNA
Zidovudine results in decreased expression of COX7B protein
CTD PMID:7807166 PMID:16894629 NCBI chr  X:106,015,700...106,022,450
Ensembl chr  X:106,015,700...106,022,450
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C decreases expression
multiple interactions
ISO
EXP
Zidovudine results in decreased expression of COX7C protein
[Zidovudine co-treated with Lamivudine] results in increased expression of COX7C mRNA
CTD PMID:7807166 PMID:18313992 NCBI chr13:86,044,798...86,046,795
Ensembl chr13:86,044,816...86,046,904
JBrowse link
G Cpne5 copine V multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CPNE5 mRNA CTD PMID:20370541 NCBI chr17:29,156,521...29,237,790
Ensembl chr17:29,155,556...29,238,167
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions
increases expression
EXP [Zidovudine co-treated with Lamivudine] results in increased expression of CPT1A mRNA
Zidovudine results in increased expression of CPT1A mRNA
CTD PMID:14576092 PMID:18313992 NCBI chr19:3,322,326...3,385,735
Ensembl chr19:3,322,334...3,385,733
JBrowse link
G Crat carnitine acetyltransferase multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of CRAT mRNA CTD PMID:18313992 NCBI chr 2:30,400,476...30,416,017
Ensembl chr 2:30,400,471...30,415,813
JBrowse link
G Cs citrate synthase affects expression
decreases expression
ISO Zidovudine affects the expression of CS mRNA
Zidovudine results in decreased expression of CS protein
CTD PMID:1892364 PMID:20032539 NCBI chr10:128,337,727...128,362,482
Ensembl chr10:128,337,734...128,362,479
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions EXP [IL3 protein co-treated with CSF2 protein] inhibits the reaction [Zidovudine results in decreased expression of CSF2RA mRNA]; [IL3 protein co-treated with CSF2 protein] inhibits the reaction [Zidovudine results in decreased expression of IL3RA mRNA] CTD PMID:12084393 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Csf2ra colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) multiple interactions
decreases expression
EXP [IL3 protein co-treated with CSF2 protein] inhibits the reaction [Zidovudine results in decreased expression of CSF2RA mRNA] CTD PMID:12084393 NCBI chr19:61,217,191...61,228,461
Ensembl chr19:61,223,957...61,228,429
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CSGALNACT1 mRNA CTD PMID:20370541 NCBI chr 8:68,356,781...68,735,621
Ensembl chr 8:68,356,781...68,735,146
JBrowse link
G Cul7 cullin 7 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in decreased expression of CUL7 mRNA CTD PMID:18313992 NCBI chr17:46,650,338...46,664,364
Ensembl chr17:46,650,337...46,664,364
JBrowse link
G Cyb5a cytochrome b5 type A (microsomal) multiple interactions
decreases expression
EXP
ISO
[Zidovudine co-treated with Lamivudine] results in increased expression of CYB5A mRNA
[Zidovudine co-treated with Isoniazid] results in decreased expression of CYB5A mRNA; silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of CYB5A mRNA]
Zidovudine results in decreased expression of CYB5A mRNA
CTD PMID:18313992 PMID:28619387 NCBI chr18:84,851,338...84,879,871
Ensembl chr18:84,838,704...84,879,871
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in decreased expression of CYP11A1 mRNA CTD PMID:18313992 NCBI chr 9:57,998,024...58,027,031
Ensembl chr 9:58,006,411...58,027,023
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of CYP1B1 mRNA CTD PMID:20370541 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061
JBrowse link
G Dcn decorin multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DCN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNA CTD PMID:16931933 NCBI chr10:97,479,500...97,518,163
Ensembl chr10:97,479,609...97,518,143
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DDIT3 mRNA
Zidovudine results in increased expression of DDIT3 mRNA
CTD PMID:15784690 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Ddr2 discoidin domain receptor family, member 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of DDR2 mRNA CTD PMID:20370541 NCBI chr 1:169,972,307...170,110,836
Ensembl chr 1:169,972,307...170,110,762
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DHFR mRNA CTD PMID:15784690 NCBI chr13:92,354,783...92,389,053
Ensembl chr13:92,354,726...92,389,053
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of DIABLO mRNA CTD PMID:18313992 NCBI chr 5:123,511,330...123,524,164
Ensembl chr 5:123,509,765...123,524,176
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of DLST mRNA CTD PMID:18313992 NCBI chr12:85,110,822...85,134,091
Ensembl chr12:85,110,833...85,134,845
JBrowse link
G Dmd dystrophin, muscular dystrophy affects localization EXP Zidovudine affects the localization of DMD protein CTD PMID:17943461 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141
JBrowse link
G Dna2 DNA replication helicase/nuclease 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of DNA2 mRNA CTD PMID:20370541 NCBI chr10:62,946,983...62,974,188
Ensembl chr10:62,947,026...62,974,185
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in decreased expression of DNAJA3 mRNA CTD PMID:18313992 NCBI chr16:4,684,070...4,707,695
Ensembl chr16:4,639,989...4,707,695
JBrowse link
G Dnm1l dynamin 1-like affects localization
multiple interactions
ISO Zidovudine affects the localization of DNM1L protein
[DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of and affects the phosphorylation of DNM1L protein; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of DNM1L mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the localization of DNM1L protein
CTD PMID:28683400 NCBI chr16:16,312,228...16,359,038
Ensembl chr16:16,312,230...16,358,959
JBrowse link
G Dtx3l deltex 3-like, E3 ubiquitin ligase multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of DTX3L mRNA CTD PMID:20370541 NCBI chr16:35,926,515...35,939,027
Ensembl chr16:35,926,511...35,939,151
JBrowse link
G Dtymk deoxythymidylate kinase multiple interactions
affects response to substance
ISO [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of and affects the phosphorylation of DNM1L protein; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of DNM1L mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of MFF mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of MFF protein; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of OPA1 mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of OPA1 protein; [DTYMK protein affects the susceptibility to Zidovudine] which affects the localization of DNM1L protein; DTYMK gene mutant form results in increased phosphorylation of and results in increased susceptibility to Zidovudine CTD PMID:17375075 PMID:28683400 NCBI chr 1:93,792,576...93,802,068
Ensembl chr 1:93,792,576...93,801,934
JBrowse link
G Dusp3 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of DUSP3 mRNA CTD PMID:16931933 NCBI chr11:101,971,141...101,987,013
Ensembl chr11:101,971,143...101,987,013
JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of ECHS1 mRNA CTD PMID:18313992 NCBI chr 7:140,105,710...140,116,421
Ensembl chr 7:140,105,710...140,116,476
JBrowse link
G Eci1 enoyl-Coenzyme A delta isomerase 1 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in decreased expression of ECI1 mRNA CTD PMID:18313992 NCBI chr17:24,426,683...24,439,316
Ensembl chr17:24,426,641...24,439,348
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases secretion
ISO coenzyme Q10 inhibits the reaction [Zidovudine results in increased secretion of EDN1 protein] CTD PMID:23640862 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Zidovudine co-treated with Arsenic Trioxide] results in increased expression of EGR1 mRNA CTD PMID:29910624 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Ehf ets homologous factor multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of EHF mRNA CTD PMID:20370541 NCBI chr 2:103,263,431...103,303,275
Ensembl chr 2:103,263,433...103,303,278
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases phosphorylation ISO Zidovudine results in increased phosphorylation of EIF2S1 protein CTD PMID:27041070 NCBI chr12:78,862,072...78,887,010
Ensembl chr12:78,861,819...78,887,010
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of EIF4EBP1 mRNA CTD PMID:15784690 NCBI chr 8:27,260,327...27,275,656
Ensembl chr 8:27,260,329...27,276,674
JBrowse link
G Elovl3 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of ELOVL3 mRNA CTD PMID:16931933 NCBI chr19:46,131,897...46,135,694
Ensembl chr19:46,131,897...46,135,694
JBrowse link
G Epo erythropoietin increases expression
multiple interactions
ISO
EXP
Zidovudine results in increased expression of EPO protein
EPO protein inhibits the reaction [Zidovudine results in decreased expression of EPOR mRNA]; EPO protein inhibits the reaction [Zidovudine results in decreased expression of FOS mRNA]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of EPOR mRNA]]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of FOS mRNA]]; Zidovudine inhibits the reaction [EPO protein binds to EPOR protein]; Zidovudine promotes the reaction [Staphylococcal Protein A results in increased expression of EPO protein]
CTD PMID:1549625 PMID:1889487 PMID:3422548 PMID:7646543 PMID:9735323 NCBI chr 5:137,483,020...137,485,816
Ensembl chr 5:137,483,020...137,533,242
JBrowse link
G Epor erythropoietin receptor multiple interactions
decreases expression
EXP EPO protein inhibits the reaction [Zidovudine results in decreased expression of EPOR mRNA]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of EPOR mRNA]]; Zidovudine inhibits the reaction [EPO protein binds to EPOR protein]
Zidovudine results in decreased expression of EPOR mRNA; Zidovudine results in decreased expression of EPOR protein
CTD PMID:1417927 PMID:7646543 NCBI chr 9:21,958,897...21,963,576
Ensembl chr 9:21,958,897...21,963,506
JBrowse link
G Epsti1 epithelial stromal interaction 1 (breast) multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of EPSTI1 mRNA CTD PMID:20370541 NCBI chr14:77,904,239...78,002,656
Ensembl chr14:77,904,239...78,002,657
JBrowse link
G Esr1 estrogen receptor 1 (alpha) affects localization ISO Zidovudine affects the localization of ESR1 protein CTD PMID:15531092 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ESR2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA CTD PMID:16931933 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Etv6 ets variant 6 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ETV6 mRNA CTD PMID:16931933 NCBI chr 6:134,035,700...134,270,158
Ensembl chr 6:134,035,700...134,270,158
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte affects expression ISO Zidovudine affects the expression of FABP4 mRNA CTD PMID:20032539 NCBI chr 3:10,204,342...10,208,616
Ensembl chr 3:10,204,088...10,208,576
JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FADS2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of FADS2 mRNA CTD PMID:16931933 NCBI chr19:10,062,765...10,101,503
Ensembl chr19:10,062,765...10,101,746
JBrowse link
G Faim Fas apoptotic inhibitory molecule multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of FAIM mRNA CTD PMID:16931933 NCBI chr 9:98,986,373...99,002,019
Ensembl chr 9:98,986,373...99,002,021
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) increases expression EXP Zidovudine results in increased expression of FAS protein CTD PMID:17943461 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) increases expression
multiple interactions
EXP
ISO
Zidovudine results in increased expression of FASLG protein
Zidovudine results in increased expression of FASLG mRNA
Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]; Hydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]; Hydralazine inhibits the reaction [Zidovudine results in increased expression of FASLG mRNA]; Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]
[Acrolein co-treated with Zidovudine] results in increased expression of FASLG protein; Acrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]; Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]; Hydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]]; Hydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]; Hydralazine inhibits the reaction [Zidovudine results in increased expression of FASLG mRNA]; Zidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]; Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]; Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]
CTD PMID:17943461 PMID:27238871 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression
affects expression
EXP
ISO
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of FASN mRNA
Zidovudine results in decreased expression of FASN protein
Zidovudine affects the expression of FASN mRNA
CTD PMID:11741158 PMID:15722030 PMID:20032539 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547
JBrowse link
G Fcgr1 Fc receptor, IgG, high affinity I multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of FCGR1A mRNA CTD PMID:20370541 NCBI chr 3:96,282,909...96,293,969
Ensembl chr 3:96,282,909...96,293,969
JBrowse link
G Fdxr ferredoxin reductase multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of FDXR mRNA CTD PMID:18313992 NCBI chr11:115,268,024...115,277,101
Ensembl chr11:115,268,024...115,277,050
JBrowse link
G Fgl2 fibrinogen-like protein 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of FGL2 mRNA CTD PMID:20370541 NCBI chr 5:21,372,673...21,378,386
Ensembl chr 5:21,372,642...21,378,374
JBrowse link
G Fh1 fumarate hydratase 1 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of FH1 mRNA CTD PMID:18313992 NCBI chr 1:175,601,378...175,625,635
Ensembl chr 1:175,600,374...175,625,635
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
decreases expression
EXP EPO protein inhibits the reaction [Zidovudine results in decreased expression of FOS mRNA]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of FOS mRNA]] CTD PMID:7646543 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [Arsenic co-treated with Zidovudine co-treated with IFNA1 protein] results in decreased expression of FOXP3 mRNA CTD PMID:23962110 NCBI chr  X:7,579,676...7,595,243
Ensembl chr  X:7,573,644...7,595,245
JBrowse link
G G0s2 G0/G1 switch gene 2 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of G0S2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of G0S2 mRNA CTD PMID:16931933 NCBI chr 1:193,272,160...193,273,188
Ensembl chr 1:193,272,161...193,273,217
JBrowse link
G G6pc glucose-6-phosphatase, catalytic multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of G6PC mRNA CTD PMID:16931933 NCBI chr11:101,367,716...101,377,903
Ensembl chr11:101,367,561...101,377,903
JBrowse link
G Ganc glucosidase, alpha; neutral C multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of GANC mRNA CTD PMID:16931933 NCBI chr 2:120,403,896...120,460,866
Ensembl chr 2:120,403,896...120,461,700
JBrowse link
G Gars glycyl-tRNA synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of GARS1 mRNA CTD PMID:15784690 NCBI chr 6:55,038,001...55,079,504
Ensembl chr 6:55,038,007...55,079,500
JBrowse link
G Gas1 growth arrest specific 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of GAS1 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of GAS1 mRNA CTD PMID:15784690 PMID:20370541 NCBI chr13:60,174,405...60,177,535
Ensembl chr13:60,174,405...60,177,365
JBrowse link
G Gata1 GATA binding protein 1 decreases activity
decreases expression
ISO Zidovudine results in decreased activity of GATA1 protein
Zidovudine results in decreased expression of GATA1 mRNA
CTD PMID:8599995 PMID:10651068 NCBI chr  X:7,959,260...7,976,663
Ensembl chr  X:7,959,260...7,978,071
JBrowse link
G Gbp2b guanylate binding protein 2b multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of GBP1 mRNA CTD PMID:20370541 NCBI chr 3:142,594,816...142,619,179
Ensembl chr 3:142,594,847...142,619,179
JBrowse link
G Gbp3 guanylate binding protein 3 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of GBP4 mRNA CTD PMID:20370541 NCBI chr 3:142,560,016...142,573,213
Ensembl chr 3:142,560,026...142,573,209
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions
increases activity
ISO Isoniazid promotes the reaction [Zidovudine results in increased activity of GPT protein]; Silybin inhibits the reaction [Isoniazid promotes the reaction [Zidovudine results in increased activity of GPT protein]] CTD PMID:28619387 NCBI chr15:76,696,726...76,699,675
Ensembl chr15:76,695,716...76,699,686
JBrowse link
G Grb7 growth factor receptor bound protein 7 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of GRB7 mRNA CTD PMID:20370541 NCBI chr11:98,446,834...98,455,373
Ensembl chr11:98,446,394...98,455,373
JBrowse link
G Grhl2 grainyhead like transcription factor 2 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in decreased expression of GRHL2 mRNA CTD PMID:16931933 NCBI chr15:37,232,821...37,363,569
Ensembl chr15:37,233,036...37,363,569
JBrowse link
G Gtf2h1 general transcription factor II H, polypeptide 1 increases expression ISO Zidovudine results in increased expression of GTF2H1 mRNA; Zidovudine results in increased expression of GTF2H1 protein CTD PMID:21192964 NCBI chr 7:46,796,094...46,823,800
Ensembl chr 7:46,796,103...46,823,800
JBrowse link
G Gucy1b1 guanylate cyclase 1, soluble, beta 1 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of GUCY1B1 mRNA CTD PMID:16931933 NCBI chr 3:82,032,004...82,074,711
Ensembl chr 3:82,032,006...82,074,689
JBrowse link
G Gypa glycophorin A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased mutagenesis of GYPA gene CTD PMID:17358027 NCBI chr 8:80,494,045...80,510,785
Ensembl chr 8:80,493,781...80,510,542
JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 affects expression ISO Zidovudine affects the expression of HLA-B mRNA CTD PMID:25811541 NCBI chr17:37,480,851...37,483,554
Ensembl chr17:37,480,851...37,483,552
JBrowse link
G H2-Q1 histocompatibility 2, Q region locus 1 affects expression ISO Zidovudine affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr17:35,320,525...35,328,142
Ensembl chr17:35,320,405...35,325,099
JBrowse link
G H4c3 H4 clustered histone 3 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of H4C3 mRNA CTD PMID:20370541 NCBI chr13:23,698,084...23,698,458
Ensembl chr13:23,697,635...23,698,454
JBrowse link
G H4c8 H4 clustered histone 8 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of H4C9 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of H4C9 mRNA CTD PMID:16931933 NCBI chr13:23,531,044...23,531,478
Ensembl chr13:23,531,050...23,531,519
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) affects expression ISO Zidovudine affects the expression of H6PD mRNA CTD PMID:20032539 NCBI chr 4:149,979,474...150,009,023
Ensembl chr 4:149,979,475...150,009,023
JBrowse link
G Hadh hydroxyacyl-Coenzyme A dehydrogenase multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of HADH mRNA CTD PMID:16931933 NCBI chr 3:131,233,419...131,272,101
Ensembl chr 3:131,233,419...131,272,101
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of HADHA mRNA CTD PMID:18313992 NCBI chr 5:30,119,423...30,154,980
Ensembl chr 5:30,118,304...30,155,162
JBrowse link
G Hax1 HCLS1 associated X-1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HAX1 mRNA CTD PMID:15784690 NCBI chr 3:89,995,446...89,998,716
Ensembl chr 3:89,995,446...89,998,780
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain decreases expression ISO Zidovudine results in decreased expression of HBB mRNA CTD PMID:10651068
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 multiple interactions EXP [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of HCN1 mRNA CTD PMID:16931933 NCBI chr13:117,602,320...117,981,028
Ensembl chr13:117,602,320...117,987,418
JBrowse link
G Hdlbp high density lipoprotein (HDL) binding protein decreases expression ISO Zidovudine results in decreased expression of HDLBP mRNA CTD PMID:16894629 NCBI chr 1:93,405,940...93,478,917
Ensembl chr 1:93,405,940...93,478,815
JBrowse link
G Herc6 hect domain and RLD 6 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of HERC6 mRNA CTD PMID:20370541 NCBI chr 6:57,580,992...57,665,136
Ensembl chr 6:57,581,000...57,664,632
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in decreased expression of HMGCS2 mRNA CTD PMID:18313992 NCBI chr 3:98,280,431...98,310,738
Ensembl chr 3:98,280,435...98,310,738
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Zidovudine results in increased expression of HMOX1 mRNA CTD PMID:29594326 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hprt hypoxanthine guanine phosphoribosyl transferase increases mutagenesis ISO Zidovudine results in increased mutagenesis of HPRT1 exon CTD PMID:10526209 NCBI chr  X:52,988,078...53,021,660
Ensembl chr  X:52,988,137...53,021,659
JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions EXP [Zidovudine co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene CTD PMID:9766437 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in increased expression of HRK mRNA CTD PMID:16931933 NCBI chr 5:118,169,764...118,189,478
Ensembl chr 5:118,164,648...118,189,478
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 affects expression ISO Zidovudine affects the expression of HSD11B1 mRNA CTD PMID:20032539 NCBI chr 1:193,221,640...193,264,045
Ensembl chr 1:193,221,634...193,264,075
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions EXP [Zidovudine co-treated with Lamivudine] results in decreased expression of HSD3B2 mRNA CTD PMID:18313992 NCBI chr 3:98,711,107...98,724,543
Ensembl chr 3:98,709,255...98,724,543
JBrowse link
G