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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:methoxyflurane
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Accession:CHEBI:6843 term browser browse the term
Definition:An ether in which the two groups attached to the central oxygen atom are methyl and 2,2-dichloro-1,1-difluoroethyl.
Synonyms:exact_synonym: 2,2-dichloro-1,1-difluoro-1-methoxyethane;   2,2-dichloro-1,1-difluoroethyl methyl ether
 related_synonym: Formula=C3H4Cl2F2O;   InChI=1S/C3H4Cl2F2O/c1-8-3(6,7)2(4)5/h2H,1H3;   InChIKey=RFKMCNOHBTXSMU-UHFFFAOYSA-N;   Methoflurane;   Methoxyfluoran;   Methoxyfluran;   Methyl 1,1-difluoro-2,2-dichloroethyl ether;   Penthrane;   SMILES=COC(F)(F)C(Cl)Cl;   methoxyfluranum;   metoxiflurano
 xref: CAS:76-38-0;   DrugBank:DB01028;   Drug_Central:1754;   HMDB:HMDB0015162;   KEGG:C07517;   KEGG:D00544
 xref_mesh: MESH:D008733
 xref: PMID:20466829;   PMID:20809687;   PMID:21216328;   PMID:21294628;   PMID:21495948;   PMID:21884146;   PMID:22510863;   PMID:22925206;   PMID:23279561;   PMID:23615302;   PMID:23810328;   PMID:24370557;   PMID:24628924;   PMID:24644183;   PMID:24743584;   PMID:24743586;   PMID:24888759;   Wikipedia:Methoxyflurane



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methoxyflurane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of Methoxyflurane CTD PMID:7879937 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing ISO CYP2E1 protein results in increased metabolism of Methoxyflurane CTD PMID:7879937 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of Methoxyflurane CTD PMID:7879937 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions ISO Methoxyflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] CTD PMID:10683198 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 multiple interactions ISO Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 NCBI chr14:37,096,995...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions ISO Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions ISO Methoxyflurane promotes the reaction [Glycine Agents results in increased activity of GLRA1 protein] CTD PMID:10683198 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        aetiopathogenetic role 19027
          hepatotoxic agent 15120
            methoxyflurane 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organochalcogen compound 19052
                                organooxygen compound 18998
                                  ether 16923
                                    methoxyflurane 7
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