Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:methoxyflurane
go back to main search page
Accession:CHEBI:6843 term browser browse the term
Definition:An ether in which the two groups attached to the central oxygen atom are methyl and 2,2-dichloro-1,1-difluoroethyl.
Synonyms:exact_synonym: 2,2-dichloro-1,1-difluoro-1-methoxyethane;   2,2-dichloro-1,1-difluoroethyl methyl ether
 related_synonym: Formula=C3H4Cl2F2O;   InChI=1S/C3H4Cl2F2O/c1-8-3(6,7)2(4)5/h2H,1H3;   InChIKey=RFKMCNOHBTXSMU-UHFFFAOYSA-N;   Methoflurane;   Methoxyfluoran;   Methoxyfluran;   Methyl 1,1-difluoro-2,2-dichloroethyl ether;   Penthrane;   SMILES=COC(F)(F)C(Cl)Cl;   methoxyfluranum;   metoxiflurano
 xref: CAS:76-38-0;   DrugBank:DB01028;   Drug_Central:1754;   HMDB:HMDB0015162;   KEGG:C07517;   KEGG:D00544
 xref_mesh: MESH:D008733
 xref: PMID:20466829;   PMID:20809687;   PMID:21216328;   PMID:21294628;   PMID:21495948;   PMID:21884146;   PMID:22510863;   PMID:22925206;   PMID:23279561;   PMID:23615302;   PMID:23810328;   PMID:24370557;   PMID:24628924;   PMID:24644183;   PMID:24743584;   PMID:24743586;   PMID:24888759;   Wikipedia:Methoxyflurane


show annotations for term's descendants           Sort by:
 
methoxyflurane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of Methoxyflurane CTD PMID:7879937 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing ISO CYP2E1 protein results in increased metabolism of Methoxyflurane CTD PMID:7879937 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of Methoxyflurane CTD PMID:7879937 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions ISO Methoxyflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] CTD PMID:10683198 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 multiple interactions ISO Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 NCBI chr14:39,662,411...39,801,082
Ensembl chr14:39,661,968...39,798,302
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions ISO Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600
JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions ISO Methoxyflurane promotes the reaction [Glycine Agents results in increased activity of GLRA1 protein] CTD PMID:10683198 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    role 19716
      biological role 19716
        aetiopathogenetic role 18967
          hepatotoxic agent 14575
            methoxyflurane 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      carbon group element atom 19574
                        carbon atom 19564
                          organic molecular entity 19564
                            heteroorganic entity 19199
                              organochalcogen compound 18946
                                organooxygen compound 18873
                                  ether 16633
                                    methoxyflurane 7
paths to the root