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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:myristicin
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Accession:CHEBI:68234 term browser browse the term
Definition:An organic molecular entity that has formula C11H12O3.
Synonyms:related_synonym: 1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)-;   6-Allyl-4-methoxy-1,3-benzodioxole;   Benzene, 5-allyl-1-methoxy-2,3-(methylenedioxy)-;   Formula=C11H12O3;   InChI=1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3;   InChIKey=BNWJOHGLIBDBOB-UHFFFAOYSA-N;   SMILES=C12=C(OCO1)C=C(C=C2OC)CC=C
 alt_id: CHEBI:7057
 xref: CAS:607-91-0;   HMDB:HMDB0035873;   KEGG:C10480;   KNApSAcK:C00002762
 xref_mesh: MESH:C005246
 xref: PMID:20879744;   PMID:21049975


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myristicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases expression ISO myristicin results in decreased expression of ABL1 mRNA CTD PMID:24792648 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Ankrd17 ankyrin repeat domain 17 decreases expression ISO myristicin results in decreased expression of ANKRD17 mRNA CTD PMID:24792648 NCBI chr14:19,291,025...19,431,521
Ensembl chr14:19,318,565...19,431,515
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO myristicin results in decreased expression of ATM mRNA CTD PMID:24792648 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO myristicin results in increased expression of BAX mRNA CTD PMID:29174417 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO myristicin results in decreased expression of BCL2 mRNA CTD PMID:29174417 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO myristicin results in decreased expression of BRCA1 mRNA CTD PMID:24792648 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression ISO myristicin results in decreased expression of BTG2 mRNA CTD PMID:24792648 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Casp3 caspase 3 increases activity ISO myristicin results in increased activity of CASP3 protein CTD PMID:24792648 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases activity ISO myristicin results in increased activity of CASP9 protein CTD PMID:29174417 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression ISO myristicin results in increased expression of CDK7 mRNA CTD PMID:24792648 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Chek2 checkpoint kinase 2 decreases expression ISO myristicin results in decreased expression of CHEK2 mRNA CTD PMID:24792648 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO myristicin results in increased expression of CYP1A1 mRNA
myristicin results in increased expression of and results in increased activity of CYP1A1 protein
CTD PMID:9168900 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects oxidation
decreases activity
multiple interactions
ISO CYP1A2 protein affects the oxidation of myristicin
myristicin results in decreased activity of CYP1A2 protein
Glutathione inhibits the reaction [myristicin results in decreased activity of CYP1A2 protein]
CTD PMID:12523956, PMID:26091900 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Dmc1 DNA meiotic recombinase 1 decreases expression ISO myristicin results in decreased expression of DMC1 mRNA CTD PMID:24792648 NCBI chr 7:120,796,217...120,840,524
Ensembl chr 7:120,796,217...120,839,577
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO myristicin results in decreased expression of ERCC1 mRNA CTD PMID:24792648 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO myristicin results in decreased expression of ERCC2 mRNA CTD PMID:24792648 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO myristicin results in decreased expression of FEN1 mRNA CTD PMID:24792648 NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO myristicin results in decreased expression of GADD45A mRNA CTD PMID:24792648 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression ISO myristicin results in decreased expression of GADD45G mRNA CTD PMID:24792648 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Hus1 HUS1 checkpoint clamp component decreases expression ISO myristicin results in decreased expression of HUS1 mRNA CTD PMID:24792648 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825
JBrowse link
G Ighmbp2 immunoglobulin mu DNA binding protein 2 decreases expression ISO myristicin results in decreased expression of IGHMBP2 mRNA CTD PMID:24792648 NCBI chr 1:218,509,274...218,531,922
Ensembl chr 1:218,508,950...218,532,142
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 decreases expression ISO myristicin results in decreased expression of MAP3K20 mRNA CTD PMID:24792648 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 decreases expression ISO myristicin results in decreased expression of MAPK12 mRNA CTD PMID:24792648 NCBI chr 7:130,109,214...130,120,918
Ensembl chr 7:130,109,663...130,120,579
JBrowse link
G Mlh3 mutL homolog 3 decreases expression ISO myristicin results in decreased expression of MLH3 mRNA CTD PMID:24792648 NCBI chr 6:109,059,386...109,095,876
Ensembl chr 6:109,059,341...109,095,557
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease decreases expression ISO myristicin results in decreased expression of MRE11 mRNA CTD PMID:24792648 NCBI chr 8:13,304,355...13,350,329
Ensembl chr 8:13,305,152...13,352,489
JBrowse link
G Msh3 mutS homolog 3 decreases expression ISO myristicin results in decreased expression of MSH3 mRNA CTD PMID:24792648 NCBI chr 2:21,790,048...21,931,791
Ensembl chr 2:21,790,044...21,931,720
JBrowse link
G Mutyh mutY DNA glycosylase decreases expression ISO myristicin results in decreased expression of MUTYH mRNA CTD PMID:24792648 NCBI chr 5:135,663,328...135,675,348
Ensembl chr 5:135,663,371...135,675,344
JBrowse link
G N4bp2 NEDD4 binding protein 2 decreases expression ISO myristicin results in decreased expression of N4BP2 mRNA CTD PMID:24792648 NCBI chr14:43,963,353...44,092,844
Ensembl chr14:44,038,614...44,078,897
JBrowse link
G Nbn nibrin decreases expression ISO myristicin results in decreased expression of NBN mRNA CTD PMID:24792648 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression ISO myristicin results in decreased expression of OGG1 mRNA CTD PMID:24792648 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO myristicin results in increased cleavage of PARP1 protein CTD PMID:24792648 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component decreases expression ISO myristicin results in decreased expression of PMS2 mRNA CTD PMID:24792648 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase decreases expression ISO myristicin results in decreased expression of PNKP mRNA CTD PMID:24792648 NCBI chr 1:100,853,475...100,859,202
Ensembl chr 1:100,853,902...100,859,084
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression ISO myristicin results in decreased expression of PPP1R15A mRNA CTD PMID:24792648 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression ISO myristicin results in decreased expression of PRKDC mRNA CTD PMID:24792648 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Rad50 RAD50 double strand break repair protein decreases expression ISO myristicin results in decreased expression of RAD50 mRNA CTD PMID:24792648 NCBI chr10:39,002,130...39,054,042
Ensembl chr10:39,001,498...39,054,142
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO myristicin results in decreased expression of RAD51 mRNA CTD PMID:24792648 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad51b RAD51 paralog B decreases expression ISO myristicin results in decreased expression of RAD51B mRNA CTD PMID:24792648 NCBI chr 6:102,473,978...103,018,185
Ensembl chr 6:102,477,036...102,512,505
JBrowse link
G Rad9a RAD9 checkpoint clamp component A decreases expression ISO myristicin results in decreased expression of RAD9A mRNA CTD PMID:24792648 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451
JBrowse link
G Rev1 REV1, DNA directed polymerase decreases expression ISO myristicin results in decreased expression of REV1 mRNA CTD PMID:24792648 NCBI chr 9:44,714,137...44,786,330
Ensembl chr 9:44,714,386...44,786,041
JBrowse link
G Sesn1 sestrin 1 decreases expression ISO myristicin results in decreased expression of SESN1 mRNA CTD PMID:24792648 NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
JBrowse link
G Smc1a structural maintenance of chromosomes 1A decreases expression ISO myristicin results in decreased expression of SMC1A mRNA CTD PMID:24792648 NCBI chr  X:21,710,976...21,755,708
Ensembl chr  X:21,711,019...21,755,525
JBrowse link
G Tp73 tumor protein p73 decreases expression ISO myristicin results in decreased expression of TP73 mRNA CTD PMID:24792648 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Trex1 three prime repair exonuclease 1 decreases expression ISO myristicin results in decreased expression of TREX1 mRNA CTD PMID:24792648 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 decreases expression ISO myristicin results in decreased expression of XRCC2 mRNA CTD PMID:24792648 NCBI chr 4:5,842,013...5,860,516
Ensembl chr 4:5,841,998...5,860,527
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 decreases expression
increases expression
ISO myristicin results in decreased expression of XRCC3 mRNA
myristicin results in increased expression of XRCC3 mRNA
CTD PMID:24792648 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          metabolite 19262
            myristicin 46
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      p-block molecular entity 19670
                        carbon group molecular entity 19572
                          organic molecular entity 19561
                            myristicin 46
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.