CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Ginsenoside Rg5
Accession: CHEBI:67992
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Definition: A triterpenoid saponin that has formula C42H70O12.
Synonyms: related_synonym: Formula=C42H70O12; InChI=1S/C42H70O12/c1-21(2)10-9-11-22(3)23-12-16-42(8)30(23)24(45)18-28-40(6)15-14-29(39(4,5)27(40)13-17-41(28,42)7)53-38-36(34(49)32(47)26(20-44)52-38)54-37-35(50)33(48)31(46)25(19-43)51-37/h10-11,23-38,43-50H,9,12-20H2,1-8H3/b22-11+/t23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,38+,40+,41-,42-/m1/s1; InChIKey=NJUXRKMKOFXMRX-RNCAKNGISA-N; SMILES=[H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]1([H])O[C@H]1CC[C@@]2(C)[C@@]([H])(CC[C@]3(C)[C@]2([H])C[C@@H](O)[C@]2([H])[C@]([H])(CC[C@@]32C)C(\\C)=C\\CC=C(C)C)C1(C)C; beta-D-Glucopyranoside, (3beta,12beta,20E)-12-hydroxydammara-20(22),24-dien-3-yl 2-O-beta-D-glucopyranosyl-
xref: CAS:186763-78-0
xref_mesh: MESH:C572381
xref: PMID:21417387
G
Dpp4
dipeptidylpeptidase 4
multiple interactions
ISO
[Xiao-Ke-An results in increased abundance of ginsenoside Rg5] which results in decreased activity of DPP4 protein
CTD
PMID:32535096
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Hif1a
hypoxia inducible factor 1 subunit alpha
decreases activity
EXP
ginsenoside Rg5 results in decreased activity of HIF1A protein
CTD
PMID:29298510
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Nos3
nitric oxide synthase 3
increases expression
EXP
ginsenoside Rg5 results in increased expression of NOS3
CTD
PMID:29298510
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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