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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:mesalamine
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Accession:CHEBI:6775 term browser browse the term
Definition:A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Synonyms:exact_synonym: 5-amino-2-hydroxybenzoic acid
 related_synonym: 3-carboxy-4-hydroxyaniline;   5-ASA;   5-Aminosalicylic acid;   Asacol;   Asacolitin;   Canasa;   Claversal;   Fisalamine;   Formula=C7H7NO3;   Iialda;   InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11);   InChIKey=KBOPZPXVLCULAV-UHFFFAOYSA-N;   Lixacol;   Mesalazina;   Mesalazinum;   Mesasal;   Pentasa;   Rowasa;   SMILES=Nc1ccc(O)c(c1)C(O)=O;   Salofalk;   m-Aminosalicylic acid;   mesalazine;   p-Aminosalicylsaeure
 xref: Beilstein:2090421;   CAS:89-57-6;   DrugBank:DB00244;   Drug_Central:1710;   HMDB:HMDB0014389;   KEGG:D00377;   LINCS:LSM-5427
 xref_mesh: MESH:D019804
 xref: MetaCyc:CPD-12711;   PMID:10648473;   PMID:22304735;   PMID:22648999;   PMID:23137838;   PMID:23146664;   PMID:23302220;   PMID:28166217;   Reaxys:2090421;   Wikipedia:Mesalamine
 cyclic_relationship: is_conjugate_acid_of CHEBI:20551

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mesalamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Mesalamine inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:29738702 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein] CTD PMID:33412153 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Alb albumin multiple interactions EXP Mesalamine inhibits the reaction [Thioacetamide results in decreased expression of ALB protein] CTD PMID:29738702 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein] CTD PMID:24637189 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Mesalamine inhibits the reaction [Acetic Acid results in increased expression of BAX mRNA] CTD PMID:29518435 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Mesalamine inhibits the reaction [Acetic Acid results in decreased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein] CTD PMID:24637189 PMID:29518435 PMID:33412153 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions EXP Mesalamine inhibits the reaction [Acetic Acid results in increased expression of CASP3 mRNA]; Mesalamine inhibits the reaction [Thioacetamide affects the expression of CASP3 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein] CTD PMID:29518435 PMID:29738702 PMID:33412153 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 multiple interactions ISO [Mesalamine co-treated with Glucocorticoids] results in decreased expression of CCL20 mRNA; Mesalamine results in decreased expression of [IL1B protein results in increased expression of CCL20 protein]; Mesalamine results in decreased expression of [TNF protein results in increased expression of CCL20 protein] CTD PMID:16306769 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of CCL3 mRNA] CTD PMID:33130971 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases secretion ISO Mesalamine results in increased secretion of CXCL1 protein CTD PMID:12231210 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases secretion ISO Mesalamine results in increased secretion of CXCL1 protein CTD PMID:12231210 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of GCLC mRNA CTD PMID:27818126 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO Mesalamine promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:27818126 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Mesalamine inhibits the reaction [Thioacetamide results in increased activity of GPT protein] CTD PMID:29738702 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein] CTD PMID:33412153 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP		 Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with resveratrol] results in increased expression of HMOX1 mRNA]
Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]		 CTD PMID:27818126 PMID:33412153 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of PPARG protein; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin-3-O-beta-glucopyranoside] results in increased expression of PPARG protein]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Resveratrol] results in increased expression of HMOX1 mRNA]; Mesalamine promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:27818126 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein] CTD PMID:33412153 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL12B mRNA] CTD PMID:33130971 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il17a interleukin 17A multiple interactions ISO Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA] CTD PMID:33130971 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of PPARG protein; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin-3-O-beta-glucopyranoside] results in increased expression of PPARG protein]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Resveratrol] results in increased expression of HMOX1 mRNA]; Mesalamine promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:27818126 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 ISO
EXP		 Mesalamine results in increased expression of IL1B mRNA
Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]
[allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Mesalamine inhibits the reaction [Acetic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Acetic Acid results in increased expression of IL1B protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
Mesalamine results in decreased expression of [IL1B protein results in increased expression of CCL20 protein]		 CTD PMID:10743803 PMID:16306769 PMID:25729217 PMID:29518435 PMID:33130971 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein] CTD PMID:7815356 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha multiple interactions ISO Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2RA protein] CTD PMID:7815356 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il4 interleukin 4 multiple interactions EXP [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein] CTD PMID:25729217 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein] CTD PMID:33130971 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of JUN protein] CTD PMID:33130971 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP Mesalamine inhibits the reaction [Acetic Acid results in increased expression of MAPK14 mRNA] CTD PMID:29518435 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO
EXP		 Mesalamine inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
Mesalamine inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]		 CTD PMID:25079872 PMID:29518435 PMID:30365937 PMID:33130971 PMID:33412153 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein] CTD PMID:33412153 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nat1 N-acetyltransferase 1 increases acetylation ISO NAT1 protein results in increased acetylation of Mesalamine CTD PMID:15627487 NCBI chr16:22,218,217...22,238,516 JBrowse link
G Nat2 N-acetyltransferase 2 increases acetylation ISO NAT2 protein results in increased acetylation of Mesalamine CTD PMID:15627487 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO
EXP		 [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased activity of NFE2L2 protein
Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]		 CTD PMID:27818126 PMID:33412153 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO		 Mesalamine inhibits the reaction [Acetic Acid results in increased expression of NOS2 mRNA]
Mesalamine inhibits the reaction [Dextran Sulfate results in increased activity of NOS2 protein]		 CTD PMID:29518435 PMID:33130971 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein] CTD PMID:24637189 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Mesalamine results in increased cleavage of PARP1 protein CTD PMID:12663503 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of PPARG protein; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin-3-O-beta-glucopyranoside] results in increased expression of PPARG protein]
Mesalamine inhibits the reaction [Dextran Sulfate affects the localization of PPARG protein]		 CTD PMID:27818126 PMID:33130971 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Mesalamine inhibits the reaction [Acetic Acid results in increased expression of PTGS2 protein] CTD PMID:29518435 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO		 Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]
Mesalamine results in increased expression of and affects the localization of RELA protein		 CTD PMID:33130971 PMID:33412153 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases uptake
multiple interactions		 ISO SLCO1B3 protein results in increased uptake of Mesalamine
Budesonide inhibits the reaction [SLCO1B3 protein results in increased uptake of Mesalamine]; Cyclosporine inhibits the reaction [SLCO1B3 protein results in increased uptake of Mesalamine]; Pravastatin inhibits the reaction [SLCO1B3 protein results in increased uptake of Mesalamine]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Mesalamine]		 CTD PMID:21430235 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions
increases uptake		 ISO Budesonide inhibits the reaction [SLCO2B1 protein results in increased uptake of Mesalamine]; Cyclosporine inhibits the reaction [SLCO2B1 protein results in increased uptake of Mesalamine]; Pravastatin inhibits the reaction [SLCO2B1 protein results in increased uptake of Mesalamine]; Rifampin inhibits the reaction [SLCO2B1 protein results in increased uptake of Mesalamine] CTD PMID:21430235 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP Mesalamine inhibits the reaction [Thioacetamide results in increased expression of SPP1 protein] CTD PMID:29738702 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein] CTD PMID:33412153 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Mesalamine inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein] CTD PMID:29738702 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO Mesalamine results in increased expression of TIMP2 mRNA CTD PMID:10743803 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of PPARG protein; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin-3-O-beta-glucopyranoside] results in increased expression of PPARG protein]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Resveratrol] results in increased expression of HMOX1 mRNA]; Mesalamine promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine promotes the reaction [Endotoxins results in increased expression of TNF protein]; Mesalamine results in decreased expression of [TNF protein results in increased expression of CCL20 protein]
Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]
[allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Mesalamine inhibits the reaction [Acetic Acid results in increased expression of TNF protein]; Mesalamine inhibits the reaction [Thioacetamide results in increased expression of TNF protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]		 CTD PMID:7496871 PMID:16306769 PMID:25729217 PMID:27818126 PMID:29518435 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tpm3 tropomyosin 3 decreases expression ISO Mesalamine results in decreased expression of TPM3 mRNA alternative form; Mesalamine results in decreased expression of TPM3 protein alternative form CTD PMID:19369484 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Mesalamine inhibits the reaction [Acetic Acid results in increased expression of VEGFA mRNA] CTD PMID:29518435 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        antimicrobial agent 17408
          antifungal agent 15099
            salicylic acid 769
              mesalamine 48
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        aromatic carboxylic acid 11710
                                          benzoic acids 11683
                                            benzoic acid 4156
                                              hydroxybenzoic acid 3560
                                                monohydroxybenzoic acid 1289
                                                  salicylic acid 769
                                                    mesalamine 48
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