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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:merbromin
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Accession:CHEBI:6763 term browser browse the term
Definition:An organic sodium salt that is 2,7-dibromo-4-hydroxymercurifluorescein in which the carboxy group and the phenolic hydroxy group have been deprotonated and the resulting charge is neutralised by two sodium ions.
Synonyms:exact_synonym: disodium [2,7-dibromo-9-(2-carboxylatophenyl)-6-oxido-3-oxo-3H-xanthen-5-yl](hydroxy)mercury
 related_synonym: 2,7-Dibromo-4-hydroxymercurifluoresceine disodium salt;   Disodium 2',7'-dibromo-4'-(hydroxymercury)fluorescein;   Formula=C20H8Br2HgNa2O6;   Formula=C20H8Br2HgO6.2Na;   InChI=1S/C20H9Br2O5.Hg.2Na.H2O/c21-13-5-11-17(7-15(13)23)27-18-8-16(24)14(22)6-12(18)19(11)9-3-1-2-4-10(9)20(25)26;;;;/h1-7,24H,(H,25,26);;;;1H2/q;3*+1;/p-3;   InChIKey=SQFDQLBYJKFDDO-UHFFFAOYSA-K;   Mercurochrome;   SMILES=C1=C(C(C=C2C1=C(C3=C(O2)C(=C(C(=C3)Br)[O-])[Hg]O)C4=CC=CC=C4C([O-])=O)=O)Br.[Na+].[Na+];   merbromina;   merbromine;   merbrominum
 xref: CAS:129-16-8;   KEGG:D00861
 xref_mesh: MESH:D008622
 xref: PMID:11141371;   PMID:12974562;   PMID:1692875;   PMID:18061533;   PMID:26177225;   PMID:4433132;   PMID:4971331;   PMID:6177466;   PMID:88168;   Reaxys:9979863;   Wikipedia:Merbromin


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merbromin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car2 carbonic anhydrase 2 decreases activity ISO Merbromin results in decreased activity of CA2 protein CTD PMID:16858005 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Merbromin inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link

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  CHEBI ontology 19810
    role 19758
      application 19420
        dye 1299
          histological dye 150
            merbromin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic ion 8333
                              organic anion 3020
                                carboxylic acid anion 2391
                                  monocarboxylic acid anion 1489
                                    benzoates 1266
                                      2,7-dibromo-4-hydroxymercurifluorescein(2-) 2
                                        merbromin 2
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