Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:mepivacaine
go back to main search page
Accession:CHEBI:6759 term browser browse the term
Definition:A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
Synonyms:related_synonym: 1-methyl-2',6'-pipecoloxylidide;   Carbocaine;   DL-Mepivacaine;   Formula=C15H22N2O;   InChI=1S/C15H22N2O/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);   InChIKey=INWLQCZOYSRPNW-UHFFFAOYSA-N;   N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide;   N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide;   SMILES=CN1CCCCC1C(=O)Nc1c(C)cccc1C;   mepivacaina;   mepivacainum
 alt_id: CHEBI:247981
 xref: Beilstein:211230;   CAS:96-88-8;   DrugBank:DB00961;   Drug_Central:1700;   HMDB:HMDB0015096;   KEGG:C07528;   KEGG:D08181;   LINCS:LSM-4306
 xref_mesh: MESH:D008619
 xref: PMID:13760073;   PMID:13859098;   PMID:25369391;   PMID:25827158;   PMID:26169676;   PMID:26780408;   PMID:9013953;   PMID:9425972;   PMID:9989796;   Patent:US2799679;   Reaxys:211230;   Wikipedia:Mepivacaine


show annotations for term's descendants           Sort by:
 
mepivacaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions ISO Mepivacaine results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16931984 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 decreases activity
multiple interactions
ISO Mepivacaine results in decreased activity of KCNQ1 protein
Mepivacaine results in decreased activity of [KCNQ1 protein binds to KCNE1 protein]
CTD PMID:16931984 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity EXP Mepivacaine results in increased activity of TRPV1 protein CTD PMID:18172555 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19767
    role 19714
      application 19403
        pharmaceutical 19303
          drug 19303
            drug allergen 9928
              mepivacaine 3
                mepivacaine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19767
    subatomic particle 19766
      composite particle 19766
        hadron 19766
          baryon 19766
            nucleon 19766
              atomic nucleus 19766
                atom 19766
                  main group element atom 19657
                    p-block element atom 19657
                      carbon group element atom 19573
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18599
                              organic divalent group 18590
                                organodiyl group 18590
                                  carbonyl group 18505
                                    carbonyl compound 18505
                                      carboxylic acid 18156
                                        carboacyl group 17415
                                          univalent carboacyl group 17415
                                            carbamoyl group 17212
                                              carboxamide 17212
                                                monocarboxylic acid amide 14604
                                                  piperidinecarboxamide 30
                                                    mepivacaine 3
                                                      mepivacaine hydrochloride 0
paths to the root