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Term:minabeolide 5
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Accession:CHEBI:67569 term browser browse the term
Definition:A withanolide that is (22R,25S)-22,26-epoxycholesta-1,4-dien-26-one substituted by an oxo group at position 3 and an acetoxy group at position 18. Isolated from Paraminabea acronocephala, it exhibits anti-inflammatory activity.
Synonyms:exact_synonym: (22R,25S)-3,26-dioxo-22,26-epoxycholesta-1,4-dien-18-yl acetate
 related_synonym: 28-nor-3-oxo-18-acetoxy-witha-1,4-dienolide;   Formula=C29H40O5;   InChI=1S/C29H40O5/c1-17-5-10-26(34-27(17)32)18(2)23-8-9-25-22-7-6-20-15-21(31)11-13-28(20,4)24(22)12-14-29(23,25)16-33-19(3)30/h11,13,15,17-18,22-26H,5-10,12,14,16H2,1-4H3/t17-,18-,22+,23+,24-,25-,26+,28-,29-/m0/s1;   InChIKey=KMDRJFYWGCLAGL-NXAGNEQWSA-N;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3([H])CC[C@]12COC(C)=O)[C@H](C)[C@H]1CC[C@H](C)C(=O)O1
 xref: PMID:21425785 "Europe PMC";   Reaxys:21534306 "Reaxys"

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  CHEBI ontology 23754
    role 23643
      application 23039
        anti-inflammatory agent 15941
          minabeolide 5 0
Path 2
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  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  main group element atom 23522
                    p-block element atom 23522
                      carbon group element atom 23232
                        carbon atom 23208
                          organic molecular entity 23208
                            organic group 21897
                              organic divalent group 21869
                                organodiyl group 21869
                                  carbonyl group 21840
                                    carbonyl compound 21840
                                      carboxylic acid 20885
                                        monocarboxylic acid 19768
                                          acetic acid 10904
                                            acetate ester 3281
                                              minabeolide 5 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.