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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:67559 term browser browse the term
Definition:A macrolide that is the 7-oxo derivative of zeaenol (the 5Z stereoisomer). Isolated from Fungi, it exhibits cytotoxic, antibacterial and inhibitory activity against NF-kappaB.
Synonyms:exact_synonym: (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione
 related_synonym: Formula=C19H22O7;   InChI=1S/C19H22O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h3-4,6-7,9-11,15,18,21-23H,5,8H2,1-2H3/b6-4+,7-3-/t11-,15-,18+/m0/s1;   InChIKey=NEQZWEXWOFPKOT-BYRRXHGESA-N;   LL-Z1640-2;   SMILES=COc1cc(O)c2C(=O)O[C@@H](C)C\\C=C/C(=O)[C@@H](O)[C@@H](O)C\\C=C\\c2c1
 xref: PMID:21513293;   Reaxys:8800797

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5Z-7-oxozeaenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO (5Z)-7-oxozeaenol decreases expression of BIRC3 protein in esophageal adenocarcinoma cells RGD PMID:26291056 RGD:152999007 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19715
    role 19690
      biological role 19688
        biochemical role 19395
          metabolite 19380
            5Z-7-oxozeaenol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19715
    subatomic particle 19713
      composite particle 19713
        hadron 19713
          baryon 19713
            nucleon 19713
              atomic nucleus 19713
                atom 19713
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19606
                        carbon atom 19603
                          organic molecular entity 19603
                            organic group 18792
                              organic divalent group 18777
                                organodiyl group 18777
                                  carbonyl group 18743
                                    carbonyl compound 18743
                                      ketone 17080
                                        oxyketone 8789
                                          alpha-oxyketone 8789
                                            alpha-hydroxy ketone 8789
                                              secondary alpha-hydroxy ketone 978
                                                5Z-7-oxozeaenol 1
paths to the root