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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tamarixetin
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Accession:CHEBI:67492 term browser browse the term
Definition:A monomethoxyflavone that is quercetin methylated at position O-4'. Isolated from Cyperus teneriffae.
Synonyms:exact_synonym: 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one
 related_synonym: 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone;   4'-Methoxy-3,3',5,7-tetrahydroxyflavone;   4'-Methoxyquercetin;   Formula=C16H12O7;   InChI=1S/C16H12O7/c1-22-11-3-2-7(4-9(11)18)16-15(21)14(20)13-10(19)5-8(17)6-12(13)23-16/h2-6,17-19,21H,1H3;   InChIKey=FPLMIPQZHHQWHN-UHFFFAOYSA-N;   Quercetin 4'-methyl ether;   SMILES=COc1ccc(cc1O)-c1oc2cc(O)cc(O)c2c(=O)c1O
 alt_id: CHEBI:9393
 xref: CAS:603-61-2;   KEGG:C10188;   KNApSAcK:C00004636
 xref_mesh: MESH:C508967
 xref: PMID:23319447;   Reaxys:324993


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tamarixetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO tamarixetin results in increased expression of ABCB1 mRNA CTD PMID:26238175 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO tamarixetin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:17090139 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO tamarixetin results in decreased phosphorylation of AKT1 protein CTD PMID:12826665 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Casp3 caspase 3 increases activity ISO tamarixetin results in increased activity of CASP3 protein CTD PMID:12826665 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO tamarixetin results in increased expression of CYP1A2 mRNA CTD PMID:19034627 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression ISO tamarixetin results in increased expression of CYP3A4 mRNA CTD PMID:26238175 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO tamarixetin results in increased expression of CYP3A5 mRNA CTD PMID:26238175 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO tamarixetin binds to and results in increased activity of NR1I2 protein
tamarixetin results in increased activity of NR1I2 protein
CTD PMID:26238175 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases activity ISO tamarixetin results in decreased activity of PTGS2 protein CTD PMID:15292928 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link

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  CHEBI ontology 19841
    role 19792
      chemical role 19309
        antioxidant 14234
          tamarixetin 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic molecule 19556
                              organic cyclic compound 19365
                                organic heterocyclic compound 18486
                                  oxacycle 17278
                                    benzopyran 10148
                                      1-benzopyran 9864
                                        flavonoid 6376
                                          flavones 4170
                                            hydroxyflavone 4158
                                              flavonols 4072
                                                7-hydroxyflavonol 4051
                                                  quercetin 4000
                                                    tamarixetin 9
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