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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dolastatin 10
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Accession:CHEBI:67357 term browser browse the term
Definition:A tetrapeptide that is isolated from the sea hare Dolabella auricularia. It is a potent anticancer agent which inhibits tubulin polymerization.
Synonyms:exact_synonym: N,N-dimethyl-L-valyl-N-[(3R,4S,5S)-3-methoxy-1-{(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidin-1-yl}-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide
 related_synonym: DLS-10;   Formula=C42H68N6O6S
 alt_id: CHEBI:4684
 xref: CAS:110417-88-4;   Chemspider:7986684;   DrugBank:DB12730;   KEGG:C11280;   KNApSAcK:C00044726;   LINCS:LSM-45943;   PMID:21472238;   PMID:21534541;   PMID:2353935;   PMID:25431858;   PMID:28682414;   PMID:28885014;   PMID:29454703;   PMID:30023909;   PMID:31460552;   PMID:31830440;   PMID:32026730;   PMID:32323990;   PMID:8471072

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    role 19711
      biological role 19711
        biochemical role 19301
          apoptosis inducer 11019
            dolastatin 10 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic group 18593
                              organic divalent group 18584
                                organodiyl group 18584
                                  carbonyl group 18499
                                    carbonyl compound 18499
                                      carboxylic acid 18151
                                        carboacyl group 17410
                                          univalent carboacyl group 17410
                                            carbamoyl group 17208
                                              carboxamide 17208
                                                peptide 9416
                                                  oligopeptide 1245
                                                    tetrapeptide 25
                                                      dolastatin 10 0
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