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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(-)-lariciresinol
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Accession:CHEBI:67244 term browser browse the term
Definition:A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2R,3S,4S-diastereomer).
Synonyms:exact_synonym: 4-[(2R,3S,4S)-4-(4-hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl]-2-methoxyphenol
 related_synonym: Formula=C20H24O6;   InChI=1S/C20H24O6/c1-24-18-8-12(3-5-16(18)22)7-14-11-26-20(15(14)10-21)13-4-6-17(23)19(9-13)25-2/h3-6,8-9,14-15,20-23H,7,10-11H2,1-2H3/t14-,15-,20+/m1/s1;   InChIKey=MHXCIKYXNYCMHY-SXGZJXTBSA-N;   SMILES=COc1cc(C[C@@H]2CO[C@H]([C@@H]2CO)c2ccc(O)c(OC)c2)ccc1O
 xref: CAS:83327-19-9
 xref_mesh: MESH:C060282
 xref: MetaCyc:CPD-8908;   PMID:21679690;   PMID:22218086;   PMID:22466741;   PMID:8262939;   Reaxys:5622895
 cyclic_relationship: is_enantiomer_of CHEBI:67246


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(-)-lariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 increases expression ISO lariciresinol results in increased expression of ANXA1 protein CTD PMID:27417256 NCBI chr19:20,373,434...20,390,671
Ensembl chr19:20,373,428...20,390,944
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO lariciresinol results in decreased expression of BASP1 protein CTD PMID:27417256 NCBI chr15:25,363,277...25,413,764
Ensembl chr15:25,363,277...25,413,764
JBrowse link
G Gale galactose-4-epimerase, UDP increases expression ISO lariciresinol results in increased expression of GALE protein CTD PMID:27417256 NCBI chr 4:135,963,681...135,968,178
Ensembl chr 4:135,963,727...135,968,178
JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic increases expression ISO lariciresinol results in increased expression of GAPDHS protein CTD PMID:27417256 NCBI chr 7:30,729,779...30,744,791
Ensembl chr 7:30,729,775...30,743,681
JBrowse link
G Hp haptoglobin decreases expression ISO lariciresinol results in decreased expression of HP protein CTD PMID:27417256 NCBI chr 8:109,575,128...109,579,172
Ensembl chr 8:109,575,128...109,579,172
JBrowse link
G Hspb1 heat shock protein 1 decreases expression ISO lariciresinol results in decreased expression of HSPB1 protein CTD PMID:27417256 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563
JBrowse link
G Tmod2 tropomodulin 2 decreases expression ISO lariciresinol results in decreased expression of TMOD2 protein CTD PMID:27417256 NCBI chr 9:75,565,621...75,611,342
Ensembl chr 9:75,565,621...75,611,325
JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO lariciresinol results in decreased expression of TUBA1A protein CTD PMID:27417256 NCBI chr15:98,949,847...98,953,501
Ensembl chr15:98,949,837...98,953,703
JBrowse link
G Ubc ubiquitin C increases expression ISO lariciresinol results in increased expression of UBC protein CTD PMID:27417256 NCBI chr 5:125,385,965...125,390,017
Ensembl chr 5:125,385,965...125,390,202
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21727
    chemical entity 21725
      molecular entity 21712
        polyatomic entity 21602
          heteroatomic molecular entity 21534
            hydroxides 20161
              organic hydroxy compound 19184
                phenols 18476
                  (-)-lariciresinol 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 21727
    subatomic particle 21713
      composite particle 21713
        hadron 21713
          baryon 21713
            nucleon 21713
              atomic nucleus 21713
                atom 21713
                  main group element atom 21629
                    p-block element atom 21629
                      carbon group element atom 21434
                        carbon atom 21334
                          organic molecular entity 21334
                            organic molecule 21228
                              organic cyclic compound 20811
                                organic aromatic compound 20240
                                  phenylpropanoid 9687
                                    lignan 1644
                                      (-)-lariciresinol 9
paths to the root