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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(-)-lariciresinol
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Accession:CHEBI:67244 term browser browse the term
Definition:A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2R,3S,4S-diastereomer).
Synonyms:exact_synonym: 4-[(2R,3S,4S)-4-(4-hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl]-2-methoxyphenol
 related_synonym: Formula=C20H24O6;   InChI=1S/C20H24O6/c1-24-18-8-12(3-5-16(18)22)7-14-11-26-20(15(14)10-21)13-4-6-17(23)19(9-13)25-2/h3-6,8-9,14-15,20-23H,7,10-11H2,1-2H3/t14-,15-,20+/m1/s1;   InChIKey=MHXCIKYXNYCMHY-SXGZJXTBSA-N;   SMILES=COc1cc(C[C@@H]2CO[C@H]([C@@H]2CO)c2ccc(O)c(OC)c2)ccc1O
 xref: CAS:83327-19-9
 xref_mesh: MESH:C060282
 xref: MetaCyc:CPD-8908;   PMID:21679690;   PMID:22218086;   PMID:22466741;   PMID:8262939;   Reaxys:5622895
 cyclic_relationship: is_enantiomer_of CHEBI:67246


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(-)-lariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 increases expression EXP lariciresinol results in increased expression of ANXA1 protein CTD PMID:27417256 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G BASP1 brain abundant membrane attached signal protein 1 decreases expression EXP lariciresinol results in decreased expression of BASP1 protein CTD PMID:27417256 NCBI chr 5:17,216,823...17,276,834
Ensembl chr 5:17,065,598...17,276,843
JBrowse link
G GALE UDP-galactose-4-epimerase increases expression EXP lariciresinol results in increased expression of GALE protein CTD PMID:27417256 NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781
JBrowse link
G GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic increases expression EXP lariciresinol results in increased expression of GAPDHS protein CTD PMID:27417256 NCBI chr19:35,533,456...35,545,319
Ensembl chr19:35,533,455...35,545,319
JBrowse link
G HP haptoglobin decreases expression EXP lariciresinol results in decreased expression of HP protein CTD PMID:27417256 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 decreases expression EXP lariciresinol results in decreased expression of HSPB1 protein CTD PMID:27417256 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G TMOD2 tropomodulin 2 decreases expression EXP lariciresinol results in decreased expression of TMOD2 protein CTD PMID:27417256 NCBI chr15:51,751,561...51,816,363
Ensembl chr15:51,751,597...51,816,363
JBrowse link
G TUBA1A tubulin alpha 1a decreases expression EXP lariciresinol results in decreased expression of TUBA1A protein CTD PMID:27417256 NCBI chr12:49,184,795...49,189,080
Ensembl chr12:49,184,795...49,189,080
Ensembl chr12:49,184,795...49,189,080
JBrowse link
G UBC ubiquitin C increases expression EXP lariciresinol results in increased expression of UBC protein CTD PMID:27417256 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24513
    chemical entity 24481
      molecular entity 24446
        polyatomic entity 24374
          heteroatomic molecular entity 23977
            hydroxides 22508
              organic hydroxy compound 20794
                phenols 19502
                  (-)-lariciresinol 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 24513
    subatomic particle 24471
      composite particle 24471
        hadron 24471
          baryon 24471
            nucleon 24471
              atomic nucleus 24471
                atom 24471
                  main group element atom 24329
                    p-block element atom 24329
                      carbon group element atom 24114
                        carbon atom 24076
                          organic molecular entity 24076
                            organic molecule 23957
                              organic cyclic compound 23156
                                organic aromatic compound 22811
                                  phenylpropanoid 9981
                                    lignan 1675
                                      (-)-lariciresinol 9
paths to the root