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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:conduritol epoxide
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Accession:CHEBI:67235 term browser browse the term
Definition:An epoxide resulting from the epoxidation of the double bond of a conduritol.
Synonyms:exact_synonym: 7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
 related_synonym: Formula=C6H10O5;   InChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H;   InChIKey=ZHMWOVGZCINIHW-UHFFFAOYSA-N;   SMILES=OC1C(O)C(O)C2OC2C1O


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conduritol B epoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta multiple interactions
decreases activity
ISO
EXP
[conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein
[conduritol epoxide binds to and results in decreased activity of GBA protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein
conduritol epoxide analog results in decreased activity of GBA protein
CTD PMID:9101438 PMID:19576930 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Snca synuclein alpha multiple interactions ISO [conduritol epoxide binds to and results in decreased activity of GBA protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein CTD PMID:19576930 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    chemical entity 19770
      molecular entity 19768
        main group molecular entity 19662
          gas molecular entity 17751
            oxirane 9519
              epoxide 9518
                conduritol epoxide 2
                  1-D-1,2-anhydro-myo-inositol + 2
                  1-L-1,2-anhydro-myo-inositol + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    main group molecular entity 19662
                      s-block molecular entity 19429
                        hydrogen molecular entity 19423
                          hydrides 18758
                            organic hydride 18356
                              organic fundamental parent 18356
                                hydrocarbon 18075
                                  olefin 5469
                                    cyclic olefin 108
                                      monocyclic olefin 105
                                        cycloalkene 96
                                          cyclohexene 3
                                            conduritol 2
                                              conduritol epoxide 2
                                                1-D-1,2-anhydro-myo-inositol + 2
                                                1-L-1,2-anhydro-myo-inositol + 2
paths to the root