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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:conduritol epoxide
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Accession:CHEBI:67235 term browser browse the term
Definition:An epoxide resulting from the epoxidation of the double bond of a conduritol.
Synonyms:exact_synonym: 7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
 related_synonym: Formula=C6H10O5;   InChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H;   InChIKey=ZHMWOVGZCINIHW-UHFFFAOYSA-N;   SMILES=OC1C(O)C(O)C2OC2C1O



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conduritol B epoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta multiple interactions
decreases activity
ISO
EXP
[conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein
[conduritol epoxide binds to and results in decreased activity of GBA protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein
conduritol epoxide analog results in decreased activity of GBA protein
CTD PMID:9101438 PMID:19576930 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Snca synuclein alpha multiple interactions ISO [conduritol epoxide binds to and results in decreased activity of GBA protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein CTD PMID:19576930 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    chemical entity 20049
      molecular entity 20047
        main group molecular entity 19948
          gas molecular entity 18247
            oxirane 9778
              epoxide 9777
                conduritol epoxide 2
                  1-D-1,2-anhydro-myo-inositol + 2
                  1-L-1,2-anhydro-myo-inositol + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    main group molecular entity 19948
                      s-block molecular entity 19735
                        hydrogen molecular entity 19727
                          hydrides 19093
                            organic hydride 18613
                              organic fundamental parent 18613
                                hydrocarbon 18366
                                  olefin 8752
                                    cyclic olefin 108
                                      monocyclic olefin 105
                                        cycloalkene 96
                                          cyclohexene 3
                                            conduritol 2
                                              conduritol epoxide 2
                                                1-D-1,2-anhydro-myo-inositol + 2
                                                1-L-1,2-anhydro-myo-inositol + 2
paths to the root