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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1-D-1,2-anhydro-myo-inositol
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Accession:CHEBI:67233 term browser browse the term
Definition:A conduritol epoxide resulting from the formal epoxidation of the double bond of (+)-conduritol B.
Synonyms:exact_synonym: (1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
 related_synonym: (1R,2R,3S,4S,5R,6S)-2,3,4,5-tetraol-7-oxabicyclo[4.1.0]heptane;   1D-conduritol B epoxide;   Formula=C6H10O5;   InChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H/t1-,2-,3+,4+,5-,6+/m0/s1;   InChIKey=ZHMWOVGZCINIHW-FTYOSCRSSA-N;   SMILES=O[C@H]1[C@H](O)[C@@H](O)[C@H]2O[C@H]2[C@@H]1O
 xref: PMID:560212;   Reaxys:1680620
 cyclic_relationship: is_enantiomer_of CHEBI:67234


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conduritol B epoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta multiple interactions
decreases activity
ISO
EXP
[conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein
[conduritol epoxide binds to and results in decreased activity of GBA protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein
conduritol epoxide analog results in decreased activity of GBA protein
CTD PMID:9101438, PMID:19576930 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Snca synuclein alpha multiple interactions ISO [conduritol epoxide binds to and results in decreased activity of GBA protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein CTD PMID:19576930 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    chemical entity 19791
      molecular entity 19787
        main group molecular entity 19675
          gas molecular entity 17570
            oxirane 5738
              epoxide 5736
                conduritol epoxide 2
                  1-D-1,2-anhydro-myo-inositol 2
                    conduritol B epoxide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19792
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19675
                    main group molecular entity 19675
                      s-block molecular entity 19420
                        hydrogen molecular entity 19411
                          hydrides 18460
                            organic hydride 17773
                              organic fundamental parent 17773
                                hydrocarbon 17294
                                  olefin 7195
                                    cyclic olefin 106
                                      monocyclic olefin 103
                                        cycloalkene 94
                                          cyclohexene 3
                                            conduritol 2
                                              (+)-conduritol B 2
                                                1-D-1,2-anhydro-myo-inositol 2
                                                  conduritol B epoxide 2
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