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G |
Acp5 |
acid phosphatase 5, tartrate resistant |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ACP5 protein] |
CTD |
PMID:25739386 |
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NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
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G |
Adgre1 |
adhesion G protein-coupled receptor E1 |
multiple interactions |
ISO |
2-Aminopurine affects the reaction [LEP protein affects the expression of ADGRE1 mRNA] |
CTD |
PMID:24150608 |
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NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
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G |
Atp6v0d2 |
ATPase H+ transporting V0 subunit D2 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 protein] |
CTD |
PMID:25739386 |
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NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
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G |
Calcr |
calcitonin receptor |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of CALCR protein] |
CTD |
PMID:25739386 |
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NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [LEP protein affects the expression of CCL2 mRNA] |
CTD |
PMID:24150608 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2-Aminopurine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:1312672 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
decreases phosphorylation decreases activity multiple interactions |
ISO |
2-Aminopurine results in decreased phosphorylation of EIF2AK2 protein 2-Aminopurine results in decreased activity of EIF2AK2 protein 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of EIF2AK2 protein] 2-Aminopurine inhibits the reaction [[IFNB1 results in increased expression of EIF2AK2 protein] which results in decreased susceptibility to Mercuric Chloride] |
CTD |
PMID:12890478 PMID:16324719 PMID:25739386 |
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NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of FOS protein]] |
CTD |
PMID:25739386 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Ifnb1 |
interferon beta 1 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [[IFNB1 results in increased expression of EIF2AK2 protein] which results in decreased susceptibility to Mercuric Chloride] |
CTD |
PMID:16324719 |
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NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
2-Aminopurine affects the reaction [LEP protein affects the expression of IL6 mRNA] |
CTD |
PMID:24150608 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Lep |
leptin |
multiple interactions |
ISO |
2-Aminopurine affects the reaction [LEP protein affects the expression of ADGRE1 mRNA]; 2-Aminopurine affects the reaction [LEP protein affects the expression of IL6 mRNA]; 2-Aminopurine affects the reaction [LEP protein affects the expression of TNF mRNA]; 2-Aminopurine inhibits the reaction [LEP protein affects the expression of CCL2 mRNA] |
CTD |
PMID:24150608 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:25739386 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:25739386 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Matk |
megakaryocyte-associated tyrosine kinase |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of MATK protein] |
CTD |
PMID:25739386 |
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NCBI chr 7:8,456,990...8,465,947
Ensembl chr 7:8,456,998...8,462,022
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G |
Nfatc1 |
nuclear factor of activated T-cells 1 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [TNF protein affects the localization of NFATC1 protein]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]] |
CTD |
PMID:25739386 |
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NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [TNF protein affects the localization of NFKB1 protein] |
CTD |
PMID:25739386 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:25739386 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [TNF protein affects the localization of RELA protein] |
CTD |
PMID:25739386 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
2-Aminopurine affects the reaction [LEP protein affects the expression of TNF mRNA]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ACP5 protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of CALCR protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of MATK protein]; 2-Aminopurine inhibits the reaction [TNF protein affects the localization of NFATC1 protein]; 2-Aminopurine inhibits the reaction [TNF protein affects the localization of NFKB1 protein]; 2-Aminopurine inhibits the reaction [TNF protein affects the localization of RELA protein]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of FOS protein]]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]]; 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of EIF2AK2 protein]; 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:24150608 PMID:25739386 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfsf11 |
TNF superfamily member 11 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ACP5 protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of CALCR protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of MATK protein]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of FOS protein]]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]] |
CTD |
PMID:25739386 |
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NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
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G |
Atm |
ATM serine/threonine kinase |
decreases methylation |
ISO |
5-hydroxymethylcytosine results in decreased methylation of ATM gene |
CTD |
PMID:30990028 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Cmah |
cytidine monophospho-N-acetylneuraminic acid hydroxylase |
multiple interactions |
ISO |
[bisphenol A results in decreased methylation of CMAH intron] which results in decreased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:30044229 |
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NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions |
ISO |
DNMT1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]; DNMT1 protein promotes the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine] |
CTD |
PMID:32105160 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dnmt3a |
DNA methyltransferase 3 alpha |
multiple interactions |
ISO |
DNMT3A protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]; DNMT3A protein promotes the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine] |
CTD |
PMID:32105160 |
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NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
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G |
Esr1 |
estrogen receptor 1 |
decreases abundance multiple interactions |
ISO |
ESR1 protein results in decreased abundance of 5-hydroxymethylcytosine ESR1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]; ESR1 protein promotes the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine] |
CTD |
PMID:32105160 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Ftl1 |
ferritin light chain 1 |
multiple interactions |
ISO |
[Chloranil results in increased abundance of 5-hydroxymethylcytosine] which results in increased expression of FTL mRNA |
CTD |
PMID:24214992 |
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NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
[hydroquinone affects the methylation of GCLC promoter] which results in increased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:23940045 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gnas |
GNAS complex locus |
multiple interactions |
ISO |
[bisphenol A results in increased methylation of GNAS intron] which results in increased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:30044229 |
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NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262 Ensembl chr 3:163,071,417...163,127,262
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G |
Grb10 |
growth factor receptor bound protein 10 |
multiple interactions |
ISO |
[bisphenol A results in increased methylation of GRB10 intron] which results in increased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:30044229 |
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NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
decreases abundance |
ISO |
IDH2 protein mutant form results in decreased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:27469509 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Kcnq1 |
potassium voltage-gated channel subfamily Q member 1 |
multiple interactions |
ISO |
[bisphenol A results in decreased methylation of KCNQ1 intron] which results in decreased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:30044229 |
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NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
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G |
Klf14 |
KLF transcription factor 14 |
multiple interactions |
ISO |
[bisphenol A results in decreased methylation of KLF14 exon] which results in decreased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:30044229 |
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NCBI chr 4:59,554,011...59,556,933
Ensembl chr 4:59,554,011...59,556,933
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G |
Pde10a |
phosphodiesterase 10A |
multiple interactions |
ISO |
[bisphenol A results in increased methylation of PDE10A intron] which results in increased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:30044229 |
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NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
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G |
Pde4d |
phosphodiesterase 4D |
multiple interactions |
ISO |
[bisphenol A results in increased methylation of PDE4D exon] which results in increased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:30044229 |
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NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
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G |
Plagl1 |
PLAG1 like zinc finger 1 |
multiple interactions |
ISO |
[bisphenol A results in increased methylation of PLAGL1 exon] which results in increased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:30044229 |
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NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
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G |
Ppp1r9a |
protein phosphatase 1, regulatory subunit 9A |
multiple interactions |
ISO |
[bisphenol A results in decreased methylation of PPP1R9A intron] which results in decreased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:30044229 |
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NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907
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G |
Sfn |
stratifin |
multiple interactions |
ISO |
[hydroquinone affects the methylation of SFN promoter] which results in increased abundance of 5-hydroxymethylcytosine |
CTD |
PMID:23940045 |
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NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
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G |
Tet1 |
tet methylcytosine dioxygenase 1 |
multiple interactions |
ISO |
TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET1 protein affects the reaction [Chloranil results in increased chemical synthesis of 5-hydroxymethylcytosine] |
CTD |
PMID:24214992 |
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NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
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G |
Tet2 |
tet methylcytosine dioxygenase 2 |
multiple interactions increases abundance |
ISO |
TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET2 protein affects the reaction [Chloranil results in increased chemical synthesis of 5-hydroxymethylcytosine] bisphenol A promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine]; bisphenol S promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine]; TET2 protein inhibits the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]; TET2 protein inhibits the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine] |
CTD |
PMID:24214992 PMID:32105160 |
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NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534
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G |
Ubc |
ubiquitin C |
multiple interactions |
ISO |
[Chloranil results in increased abundance of 5-hydroxymethylcytosine] which results in increased expression of UBC mRNA |
CTD |
PMID:24214992 |
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NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
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G |
Aars1 |
alanyl-tRNA synthetase 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of AARS1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions increases expression decreases expression |
ISO |
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 protein; [Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Fluorouracil; ABCB1 gene SNP affects the susceptibility to [Cisplatin co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] Fluorouracil results in increased expression of ABCB1 protein Fluorouracil results in decreased expression of ABCB1 mRNA |
CTD |
PMID:12576456 PMID:15239124 PMID:17287894 PMID:21332314 PMID:21833476 PMID:32800223 More...
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcb6 |
ATP binding cassette subfamily B member 6 |
decreases expression decreases response to substance |
ISO |
Fluorouracil results in decreased expression of ABCB6 mRNA ABCB6 protein results in decreased susceptibility to Fluorouracil |
CTD |
PMID:20737486 PMID:25202056 |
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NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions |
ISO |
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC1 mRNA; ABCC1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] |
CTD |
PMID:12576456 PMID:32800223 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects response to substance multiple interactions |
ISO |
ABCC2 protein affects the susceptibility to Fluorouracil [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC2 mRNA |
CTD |
PMID:16217747 PMID:32800223 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
decreases response to substance multiple interactions |
ISO |
ABCC5 protein results in decreased susceptibility to Fluorouracil 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [ABCC5 protein results in decreased susceptibility to Fluorouracil]; ABCC5 protein results in increased export of and results in decreased susceptibility to Fluorouracil |
CTD |
PMID:15897250 PMID:19077464 |
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NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
affects response to substance increases expression |
ISO |
ABCC6 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of ABCC6 protein |
CTD |
PMID:15352031 |
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NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
multiple interactions |
ISO |
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 protein; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; [Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] |
CTD |
PMID:12576456 PMID:21712253 PMID:21833476 PMID:32800223 |
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NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Abhd12b |
abhydrolase domain containing 12B |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ABHD12B mRNA |
CTD |
PMID:24737281 |
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NCBI chr 6:88,668,627...88,696,435
Ensembl chr 6:88,668,642...88,696,458
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G |
Abi1 |
abl-interactor 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of ABI1 mRNA |
CTD |
PMID:19272435 |
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NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792
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G |
Abi2 |
abl-interactor 2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ABI2 mRNA |
CTD |
PMID:19272435 |
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NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699
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G |
Acad9 |
acyl-CoA dehydrogenase family, member 9 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ACAD9 mRNA |
CTD |
PMID:34151400 |
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NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
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G |
Acadl |
acyl-CoA dehydrogenase, long chain |
increases expression |
ISO |
Fluorouracil results in increased expression of ACADL protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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G |
Ackr3 |
atypical chemokine receptor 3 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACKR3 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
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G |
Acot13 |
acyl-CoA thioesterase 13 |
affects response to substance |
ISO |
ACOT13 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851
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G |
Acot7 |
acyl-CoA thioesterase 7 |
affects response to substance |
ISO |
ACOT7 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309
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G |
Acsm3 |
acyl-CoA synthetase medium-chain family member 3 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of SAH mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
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G |
Actb |
actin, beta |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ACTB protein |
CTD |
PMID:21296659 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Actc1 |
actin, alpha, cardiac muscle 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ACTC1 protein |
CTD |
PMID:21296659 |
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NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523
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G |
Actg2 |
actin gamma 2, smooth muscle |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ACTG2 mRNA |
CTD |
PMID:16709241 |
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NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
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G |
Acy1 |
aminoacylase 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACY1 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
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G |
Adam10 |
ADAM metallopeptidase domain 10 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM10 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889
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G |
Adam3a |
ADAM metallopeptidase domain 3A |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM3A mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr16:67,299,949...67,349,970
Ensembl chr16:67,299,949...67,349,968
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G |
Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAMTS9 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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G |
Adcy9 |
adenylate cyclase 9 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ADCY9 mRNA |
CTD |
PMID:19219653 |
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NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
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G |
Add3 |
adducin 3 |
affects response to substance |
ISO |
ADD3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
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G |
Adgrg1 |
adhesion G protein-coupled receptor G1 |
affects response to substance |
ISO |
ADGRG1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
|
NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
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G |
Adgrg6 |
adhesion G protein-coupled receptor G6 |
affects response to substance |
ISO |
ADGRG6 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 1:8,812,889...8,954,239
Ensembl chr 1:8,812,904...8,954,123
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G |
Adgrl2 |
adhesion G protein-coupled receptor L2 |
affects response to substance |
ISO |
ADGRL2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
|
NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141
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G |
Adm |
adrenomedullin |
affects response to substance |
ISO |
ADM protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
|
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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G |
Adss2 |
adenylosuccinate synthase 2 |
decreases expression increases expression |
ISO |
Fluorouracil results in decreased expression of ADSS2 mRNA Fluorouracil results in increased expression of ADSS2 protein |
CTD |
PMID:15585135 PMID:16709241 PMID:16803524 |
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NCBI chr13:89,769,240...89,799,577
Ensembl chr13:89,769,244...89,799,604
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G |
Afp |
alpha-fetoprotein |
increases expression decreases expression |
ISO |
Fluorouracil results in increased expression of AFP protein Fluorouracil results in decreased expression of AFP; Fluorouracil results in decreased expression of AFP mRNA |
CTD |
PMID:20448262 PMID:21296659 PMID:26272751 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Agap3 |
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of AGAP3 mRNA |
CTD |
PMID:16709241 |
|
NCBI chr 4:10,674,746...10,724,848
Ensembl chr 4:10,674,064...10,725,244
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G |
Agr2 |
anterior gradient 2, protein disulphide isomerase family member |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of AGR2 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
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G |
Ahnak |
AHNAK nucleoprotein |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of AHNAK protein AHNAK protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 |
|
NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions increases expression |
ISO |
[Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased expression of AIFM1 protein Fluorouracil results in increased expression of AIFM1 protein [Fluorouracil co-treated with casticin] results in increased expression of AIFM1 protein |
CTD |
PMID:16168113 PMID:32270916 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Akap12 |
A-kinase anchoring protein 12 |
affects expression |
ISO |
Fluorouracil affects the expression of AKAP12 mRNA |
CTD |
PMID:16584549 |
|
NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
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G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
affects expression |
ISO |
Fluorouracil affects the expression of AKR1B10 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
affects expression affects response to substance |
ISO |
Fluorouracil affects the expression of AKR1C1 mRNA AKR1C1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 PMID:16584549 |
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NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
affects response to substance |
ISO |
AKR1C2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
affects expression affects response to substance |
ISO |
Fluorouracil affects the expression of AKR1C3 mRNA AKR1C3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 PMID:16584549 |
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NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions affects expression decreases phosphorylation affects phosphorylation increases phosphorylation |
ISO |
[Apigenin co-treated with Fluorouracil] results in decreased expression of AKT1 protein; AG 1879 inhibits the reaction [Fluorouracil results in increased phosphorylation of AKT1 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein; Nicotine affects the reaction [Fluorouracil affects the phosphorylation of AKT1 protein] Fluorouracil affects the expression of AKT1 mRNA Fluorouracil results in decreased phosphorylation of AKT1 protein Fluorouracil inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:16724238 PMID:17918158 PMID:18794807 PMID:19885610 PMID:24095863 PMID:30542770 PMID:34151400 More...
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Akt2 |
AKT serine/threonine kinase 2 |
increases expression |
ISO |
Fluorouracil results in increased expression of AKT2 protein |
CTD |
PMID:16803524 |
|
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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G |
Alb |
albumin |
multiple interactions |
ISO |
[Leucovorin co-treated with Cisplatin co-treated with Fluorouracil] results in decreased expression of ALB protein |
CTD |
PMID:20180123 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alcam |
activated leukocyte cell adhesion molecule |
affects response to substance decreases expression |
ISO |
ALCAM protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of ALCAM protein |
CTD |
PMID:15352031 |
|
NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
affects response to substance |
ISO |
ALDH1A1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Aldh1a3 |
aldehyde dehydrogenase 1 family, member A3 |
affects response to substance decreases expression |
ISO |
ALDH1A3 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of ALDH1A3 protein |
CTD |
PMID:15352031 |
|
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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G |
Aldh3a2 |
aldehyde dehydrogenase 3 family, member A2 |
affects response to substance |
ISO |
ALDH3A2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
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G |
Alg3 |
ALG3, alpha-1,3- mannosyltransferase |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ALG3 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912
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G |
Alkbh8 |
alkB homolog 8, tRNA methyltransferase |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ALKBH8 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 6:378,779...449,382
Ensembl chr 6:378,100...452,165
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G |
Amfr |
autocrine motility factor receptor |
multiple interactions |
ISO |
AMFR mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] |
CTD |
PMID:16896004 |
|
NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247
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G |
Ampd2 |
adenosine monophosphate deaminase 2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of AMPD2 mRNA |
CTD |
PMID:19219653 |
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NCBI chr 2:195,707,609...195,720,454
Ensembl chr 2:195,707,610...195,720,271
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G |
Amt |
aminomethyltransferase |
increases expression |
ISO |
Fluorouracil results in increased expression of AMT protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126
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G |
Ang |
angiogenin |
affects response to substance |
ISO |
ANG protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr15:24,312,711...24,323,361
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G |
Angpt1 |
angiopoietin 1 |
multiple interactions increases expression |
ISO |
ANGPT1 protein promotes the reaction [Fluorouracil results in increased expression of IFNA1 protein] Fluorouracil results in increased expression of ANGPT1 protein |
CTD |
PMID:17786339 |
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NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
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G |
Angpt2 |
angiopoietin 2 |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of ANGPT2 protein ANGPT2 protein promotes the reaction [Fluorouracil results in decreased expression of IFNA1 protein] |
CTD |
PMID:17786339 |
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NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
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G |
Angptl2 |
angiopoietin-like 2 |
multiple interactions |
ISO |
ANGPTL2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] |
CTD |
PMID:17327601 |
|
NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
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G |
Angptl3 |
angiopoietin-like 3 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ANGPTL3 mRNA |
CTD |
PMID:32535746 |
|
NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
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G |
Angptl4 |
angiopoietin-like 4 |
affects response to substance |
ISO |
ANGPTL4 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Ankrd1 |
ankyrin repeat domain 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of ANKRD1 mRNA |
CTD |
PMID:17039268 |
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NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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G |
Ankrd11 |
ankyrin repeat domain containing 11 |
increases expression affects expression |
ISO |
Fluorouracil results in increased expression of ANKRD11 mRNA Fluorouracil affects the expression of ANKRD11 mRNA |
CTD |
PMID:16510598 PMID:16584549 |
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NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962
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G |
Anln |
anillin, actin binding protein |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of ANLN mRNA TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANLN mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of ANLN mRNA] |
CTD |
PMID:15016801 PMID:17982676 |
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NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
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G |
Anp32e |
acidic nuclear phosphoprotein 32 family member E |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANP32E mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054
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G |
Anxa1 |
annexin A1 |
affects response to substance decreases expression |
ISO |
ANXA1 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of ANXA1 protein |
CTD |
PMID:15352031 PMID:16217747 |
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NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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G |
Anxa2 |
annexin A2 |
decreases response to substance multiple interactions increases expression |
ISO |
ANXA2 mRNA results in decreased susceptibility to Fluorouracil TP53 protein affects the reaction [Fluorouracil results in increased expression of ANXA2 mRNA] |
CTD |
PMID:15152939 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Anxa3 |
annexin A3 |
increases expression |
ISO |
Fluorouracil results in increased expression of ANXA3 mRNA |
CTD |
PMID:17039268 |
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NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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G |
Anxa4 |
annexin A4 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ANXA4 mRNA |
CTD |
PMID:15109396 |
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NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
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G |
Ap2s1 |
adaptor related protein complex 2 subunit sigma 1 |
multiple interactions |
ISO |
[Fluorouracil co-treated with irinotecan] results in decreased expression of AP2S1 mRNA |
CTD |
PMID:16391804 |
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NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905
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G |
Ap3s1 |
adaptor related protein complex 3 subunit sigma 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of AP3S1 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr18:39,462,728...39,531,622
Ensembl chr18:39,462,765...39,531,622
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G |
Ap4s1 |
adaptor related protein complex 4 subunit sigma 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of AP4S1 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 6:69,133,403...69,174,488
Ensembl chr 6:69,133,373...69,175,496
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
increases expression affects expression |
ISO |
Fluorouracil results in increased expression of APAF1 mRNA Fluorouracil affects the expression of APAF1 mRNA |
CTD |
PMID:16557594 PMID:34151400 |
|
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Apba2 |
amyloid beta precursor protein binding family A member 2 |
affects response to substance |
ISO |
APBA2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
|
NCBI chr 1:118,053,270...118,286,858
Ensembl chr 1:118,103,219...118,285,699
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G |
Apbb2 |
amyloid beta precursor protein binding family B member 2 |
affects response to substance |
ISO |
APBB2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
|
NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
increases response to substance |
ISO |
APEX1 protein mutant form results in increased susceptibility to Fluorouracil |
CTD |
PMID:19470598 |
|
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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G |
Apob |
apolipoprotein B |
multiple interactions decreases secretion decreases expression |
ISO |
ursodoxicoltaurine inhibits the reaction [Fluorouracil results in decreased expression of APOB mRNA] Fluorouracil results in decreased secretion of APOB protein |
CTD |
PMID:32535746 |
|
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoc1 |
apolipoprotein C1 |
affects response to substance |
ISO |
APOC1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
|
NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
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G |
Apoc3 |
apolipoprotein C3 |
decreases expression decreases secretion |
ISO |
Fluorouracil results in decreased expression of APOC3 mRNA Fluorouracil results in decreased secretion of APOC3 protein |
CTD |
PMID:32535746 |
|
NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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G |
Aqp6 |
aquaporin 6 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of AQP6 mRNA |
CTD |
PMID:34151400 |
|
NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:130,633,579...130,735,194 Ensembl chr 7:130,633,579...130,735,194
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G |
Aqp9 |
aquaporin 9 |
increases uptake |
EXP |
AQP9 protein results in increased uptake of Fluorouracil |
CTD |
PMID:9733774 |
|
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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G |
Areg |
amphiregulin |
affects response to substance increases expression |
ISO |
AREG affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of AREG mRNA |
CTD |
PMID:15067352 PMID:16709241 |
|
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
Arf1 |
ADP-ribosylation factor 1 |
multiple interactions |
ISO |
ARF1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] |
CTD |
PMID:18927307 |
|
NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434
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G |
Arf3 |
ADP-ribosylation factor 3 |
affects response to substance |
ISO |
ARF3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
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G |
Arfgap1 |
ADP-ribosylation factor GTPase activating protein 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of ARFGAP1 protein |
CTD |
PMID:15331170 |
|
NCBI chr 3:168,084,560...168,099,948
Ensembl chr 3:168,084,614...168,099,933
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G |
Arhgdib |
Rho GDP dissociation inhibitor beta |
affects expression |
ISO |
Fluorouracil affects the expression of ARHGDIB mRNA |
CTD |
PMID:34151400 |
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NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
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G |
Arid5b |
AT-rich interaction domain 5B |
affects response to substance |
ISO |
ARID5B protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433
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G |
Arl4c |
ADP ribosylation factor like GTPase 4C |
increases expression |
ISO |
Fluorouracil results in increased expression of ARL4C mRNA |
CTD |
PMID:16510598 |
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NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
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G |
Arl6ip5 |
ADP-ribosylation factor like GTPase 6 interacting protein 5 |
multiple interactions |
ISO |
ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Cisplatin]; ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin] |
CTD |
PMID:22452940 |
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NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
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G |
Armcx1 |
armadillo repeat containing, X-linked 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ARMCX1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr X:97,898,969...97,902,874
Ensembl chr X:97,898,883...97,903,299
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G |
Arpc3 |
actin related protein 2/3 complex, subunit 3 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ARPC3 mRNA |
CTD |
PMID:16709241 |
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NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651
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G |
Asah1 |
N-acylsphingosine amidohydrolase 1 |
affects response to substance multiple interactions |
ISO |
ASAH1 protein affects the susceptibility to Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of ASAH1 mRNA] |
CTD |
PMID:15016801 PMID:16217747 |
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NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
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G |
Ass1 |
argininosuccinate synthase 1 |
multiple interactions |
ISO |
[Fluorouracil co-treated with irinotecan] results in decreased expression of ASS1 mRNA |
CTD |
PMID:16391804 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf3 |
activating transcription factor 3 |
affects expression multiple interactions increases expression |
ISO |
Fluorouracil affects the expression of ATF3 mRNA TP53 protein affects the reaction [Fluorouracil results in increased expression of ATF3 mRNA] Fluorouracil results in increased expression of ATF3 mRNA; Fluorouracil results in increased expression of ATF3 protein |
CTD |
PMID:14665630 PMID:15016801 PMID:15205334 PMID:16557594 PMID:16709241 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
increases expression |
ISO |
Fluorouracil results in increased expression of ATF4 protein |
CTD |
PMID:29879413 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
affects expression |
ISO |
Fluorouracil affects the expression of ATF6 mRNA |
CTD |
PMID:34151400 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atg12 |
autophagy related 12 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ATG12 mRNA |
CTD |
PMID:16510598 |
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NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
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G |
Atm |
ATM serine/threonine kinase |
decreases response to substance |
ISO |
ATM protein results in decreased susceptibility to Fluorouracil |
CTD |
PMID:35608750 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Atoh8 |
atonal bHLH transcription factor 8 |
affects expression |
ISO |
Fluorouracil affects the expression of ATOH8 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
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G |
Atp5f1d |
ATP synthase F1 subunit delta |
multiple interactions affects expression |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATP5F1D mRNA] Fluorouracil affects the expression of ATP5F1D mRNA |
CTD |
PMID:15016801 PMID:34151400 |
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NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
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G |
Atp5pb |
ATP synthase peripheral stalk-membrane subunit b |
affects expression |
ISO |
Fluorouracil affects the expression of ATP5PB mRNA |
CTD |
PMID:34151400 |
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NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
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G |
Atp5pf |
ATP synthase peripheral stalk subunit F6 |
increases expression |
ISO |
Fluorouracil results in increased expression of ATP5PF mRNA |
CTD |
PMID:34151400 |
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NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
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G |
Atp5po |
ATP synthase peripheral stalk subunit OSCP |
multiple interactions |
ISO |
ATP5PO mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] |
CTD |
PMID:17327601 |
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NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
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G |
Atp7b |
ATPase copper transporting beta |
increases response to substance |
ISO |
ATP7B mRNA results in increased susceptibility to Fluorouracil |
CTD |
PMID:18593893 |
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NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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G |
Atp9a |
ATPase phospholipid transporting 9A (putative) |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of ATP9A protein ATP9A protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 |
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NCBI chr 3:157,360,354...157,467,628
Ensembl chr 3:157,360,359...157,467,818
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G |
Atxn10 |
ataxin 10 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATXN10 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087
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G |
Aurka |
aurora kinase A |
decreases expression |
ISO |
Fluorouracil results in decreased expression of AURKA mRNA |
CTD |
PMID:15205334 PMID:16557594 PMID:16709241 PMID:17039268 PMID:19272435 |
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NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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G |
Aven |
apoptosis and caspase activation inhibitor |
decreases expression increases expression |
ISO |
Fluorouracil results in decreased expression of AVEN mRNA Fluorouracil results in increased expression of AVEN mRNA |
CTD |
PMID:16510598 PMID:16709241 |
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NCBI chr 3:99,299,009...99,431,635
Ensembl chr 3:99,298,930...99,431,634
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G |
Axin1 |
axin 1 |
multiple interactions |
EXP |
5-fluorouracil inhibits the reaction [N-methyl-N-nitrosourea decreases expression of Axin1 mRNA in colon] |
RGD |
PMID:28032729 |
RGD:150530464 |
NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
EXP |
Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAD mRNA] |
CTD |
PMID:31129132 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag3 |
BAG cochaperone 3 |
affects response to substance |
ISO |
BAG3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
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G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression multiple interactions increases response to substance |
ISO |
Fluorouracil results in increased expression of BAK1; Fluorouracil results in increased expression of BAK1 mRNA; Fluorouracil results in increased expression of BAK1 protein mithramycin A inhibits the reaction [Fluorouracil results in increased expression of BAK1 protein] BAK1 mRNA results in increased susceptibility to Fluorouracil |
CTD |
PMID:9792140 PMID:15489892 PMID:16557594 PMID:18593893 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Barx2 |
BARX homeobox 2 |
increases expression |
ISO |
Fluorouracil results in increased expression of BARX2 protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr 8:30,251,132...30,319,105
Ensembl chr 8:30,251,132...30,319,013
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions affects expression increases expression decreases expression increases response to substance |
ISO EXP |
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX protein; [Docosahexaenoic Acids co-treated with Fluorouracil] results in increased expression of BAX mRNA; [Fluorouracil co-treated with gamma-Tocopherol] results in increased expression of BAX mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in increased expression of BAX protein; [SM-1 compound co-treated with Fluorouracil] results in increased expression of BAX protein; [wogonin co-treated with Fluorouracil] results in increased expression of BAX protein; Aspirin promotes the reaction [Fluorouracil results in increased expression of BAX protein]; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of BAX mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of BAX mRNA]; Fluorouracil affects the reaction [rebamipide results in decreased expression of BAX protein]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of BAX protein]; Fluorouracil promotes the reaction [andrographolide affects the folding of BAX protein]; Fluorouracil promotes the reaction [Aspirin results in increased expression of BAX protein]; Fluorouracil promotes the reaction [Plant Extracts results in increased expression of BAX protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]; rebamipide inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; SM-1 compound promotes the reaction [Fluorouracil results in increased expression of BAX mRNA] Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA] Fluorouracil results in increased expression of BAX; Fluorouracil results in increased expression of BAX mRNA; Fluorouracil results in increased expression of BAX protein [Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in increased expression of BAX protein; casticin inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; IL1RN protein affects the reaction [Fluorouracil results in increased expression of BAX protein] Fluorouracil results in decreased expression of BAX protein BAX protein results in increased susceptibility to Fluorouracil |
CTD |
PMID:9388485 PMID:9792140 PMID:11062132 PMID:11750847 PMID:12442003 PMID:15641988 PMID:15754201 PMID:15986848 PMID:16168113 PMID:16686938 PMID:16888818 PMID:17045692 PMID:17056233 PMID:17589894 PMID:18567086 PMID:18834353 PMID:19015929 PMID:19097688 PMID:19116755 PMID:20570612 PMID:20844880 PMID:22525470 PMID:23941782 PMID:25824412 PMID:28599477 PMID:29054700 PMID:30542770 PMID:31129132 PMID:31587439 PMID:32270916 PMID:32800223 PMID:38078205 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases response to substance multiple interactions increases expression |
ISO |
BBC3 protein results in increased susceptibility to Fluorouracil [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BBC3 mRNA; mithramycin A inhibits the reaction [Fluorouracil results in increased expression of BBC3 protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 protein] Fluorouracil results in increased expression of BBC3 mRNA; Fluorouracil results in increased expression of BBC3 protein |
CTD |
PMID:14665630 PMID:15016801 PMID:15489892 PMID:16481741 PMID:16557594 PMID:22525470 PMID:32800223 More...
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bbs4 |
Bardet-Biedl syndrome 4 |
multiple interactions |
ISO |
BBS4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] |
CTD |
PMID:16896004 |
|
NCBI chr 8:59,731,912...59,765,408
Ensembl chr 8:59,731,912...59,765,607
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G |
Bbx |
BBX high mobility group box domain containing |
affects response to substance |
ISO |
BBX protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251
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G |
Bcar3 |
BCAR3 adaptor protein, NSP family member |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of BCAR3 protein BCAR3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 |
|
NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
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G |
Bcat1 |
branched chain amino acid transaminase 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of BCAT1 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
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G |
Bckdha |
branched chain keto acid dehydrogenase E1 subunit alpha |
affects expression |
ISO |
Fluorouracil affects the expression of BCKDHA mRNA |
CTD |
PMID:16584549 |
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NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions affects expression affects response to substance decreases expression increases expression increases phosphorylation decreases response to substance |
ISO EXP |
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 protein; [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with Irinotecan] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with Irinotecan] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 protein; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BCL2 mRNA; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BCL2 protein; [wogonin co-treated with Fluorouracil] results in decreased expression of BCL2 protein; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA]; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of BCL2 protein]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of BCL2 mRNA]; Fluorouracil affects the reaction [rebamipide results in increased expression of BCL2 protein]; Fluorouracil promotes the reaction [gambogic acid results in decreased expression of BCL2 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; rebamipide inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; SM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BCL2 mRNA] Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein] BCL2 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of BCL2 mRNA; Fluorouracil results in increased expression of BCL2 protein [Fluorouracil co-treated with casticin] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in decreased expression of BCL2 protein; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein] Fluorouracil results in increased phosphorylation of BCL2 protein Fluorouracil results in decreased expression of BCL-2 protein; Fluorouracil results in decreased expression of BCL2; Fluorouracil results in decreased expression of BCL2 mRNA; Fluorouracil results in decreased expression of BCL2 protein BCL2 protein results in decreased susceptibility to Fluorouracil |
CTD |
PMID:7654318 PMID:9388485 PMID:14503796 PMID:15177426 PMID:15754201 PMID:15996812 PMID:16332177 PMID:16391804 PMID:16407826 PMID:16412276 PMID:16557594 PMID:16596200 PMID:16603448 PMID:16888818 PMID:16929163 PMID:17287894 PMID:17439414 PMID:17589894 PMID:18161298 PMID:18205257 PMID:18567086 PMID:18949393 PMID:19015929 PMID:19084572 PMID:20570612 PMID:20844880 PMID:23941782 PMID:28599477 PMID:29054700 PMID:30542770 PMID:31129132 PMID:31587439 PMID:32270916 PMID:32800223 PMID:37625625 PMID:38078205 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions affects response to substance increases expression decreases expression affects expression decreases response to substance |
ISO EXP |
3-methyladenine inhibits the reaction [Fluorouracil results in increased expression of BCL2L1 protein]; [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of BCL2L1 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 protein; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA]; BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]; Fluorouracil affects the reaction [rebamipide results in increased expression of BCL2L1 protein]; Gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 protein]; IFNA1 promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 mRNA]; rebamipide inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein] Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 protein] BCL2L1 protein affects the susceptibility to Fluorouracil 3-methyladenine inhibits the reaction [Fluorouracil results in increased expression of BCL2L1 protein]; casticin promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]; Fluorouracil promotes the reaction [casticin results in decreased expression of BCL2L1 protein]; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein] Fluorouracil results in increased expression of BCL2L1 mRNA; Fluorouracil results in increased expression of BCL2L1 protein Fluorouracil results in decreased expression of BCL2L1; Fluorouracil results in decreased expression of BCL2L1 mRNA; Fluorouracil results in decreased expression of BCL2L1 protein Fluorouracil affects the expression of BCL2L1 mRNA; Fluorouracil affects the expression of BCL2L1 protein BCL2L1 protein results in decreased susceptibility to Fluorouracil |
CTD |
PMID:12442003 PMID:15289866 PMID:15767554 PMID:16407826 PMID:16557594 PMID:16596200 PMID:16875599 PMID:16929163 PMID:17033717 PMID:17045692 PMID:17399942 PMID:17439414 PMID:19116755 PMID:20844880 PMID:21474236 PMID:29054700 PMID:29879413 PMID:31129132 PMID:32270916 PMID:34151400 More...
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bcl2l11 |
Bcl2-like 11 |
multiple interactions increases expression |
ISO |
Fluorouracil affects the reaction [rebamipide results in decreased expression of BCL2L11 protein]; rebamipide inhibits the reaction [Fluorouracil results in increased expression of BCL2L11 protein] |
CTD |
PMID:29054700 |
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NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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G |
Bcl2l12 |
Bcl2 like 12 |
multiple interactions |
ISO |
[Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of BCL2L12 mRNA |
CTD |
PMID:19015929 |
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NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
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G |
Bdh1 |
3-hydroxybutyrate dehydrogenase 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of BDH1 protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
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G |
Bdkrb2 |
bradykinin receptor B2 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in increased expression of BDKRB2 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
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G |
Bdnf |
brain-derived neurotrophic factor |
decreases expression |
EXP |
Fluorouracil results in decreased expression of BDNF protein |
CTD |
PMID:18702703 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bean1 |
brain expressed, associated with NEDD4, 1 |
increases expression affects response to substance |
ISO |
Fluorouracil results in increased expression of BEAN1 protein BEAN1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 |
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NCBI chr19:739,551...786,395
Ensembl chr19:739,551...787,537
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G |
Becn1 |
beclin 1 |
multiple interactions increases expression |
ISO |
BECN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] Apigenin promotes the reaction [Fluorouracil results in increased expression of BECN1 protein]; Fluorouracil promotes the reaction [Apigenin results in increased expression of BECN1 protein] |
CTD |
PMID:16896004 PMID:28025107 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bglap |
bone gamma-carboxyglutamate protein |
increases expression |
EXP |
Fluorouracil results in increased expression of BGLAP mRNA |
CTD |
PMID:16888818 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bhlhe41 |
basic helix-loop-helix family, member e41 |
affects response to substance |
ISO |
BHLHE41 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions increases expression decreases response to substance decreases expression increases response to substance |
ISO |
[Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of BID protein; BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]; Fluorouracil results in increased cleavage of and results in increased activity of BID protein; IFNA1 promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of BID protein] Fluorouracil results in increased expression of BID protein casticin inhibits the reaction [Fluorouracil results in increased expression of BID protein] BID protein mutant form results in decreased susceptibility to Fluorouracil Fluorouracil results in decreased expression of BID protein |
CTD |
PMID:15095271 PMID:15289866 PMID:15754201 PMID:21474236 PMID:32270916 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
increases expression |
ISO |
Fluorouracil results in increased expression of BIRC2 mRNA |
CTD |
PMID:17039268 |
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NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression affects expression |
ISO |
Fluorouracil results in increased expression of BIRC3 mRNA Fluorouracil affects the expression of BIRC3 mRNA |
CTD |
PMID:16557594 PMID:34151400 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases response to substance increases expression decreases expression multiple interactions affects response to substance |
ISO |
BIRC5 protein results in decreased susceptibility to Fluorouracil; BIRC5 results in decreased susceptibility to Fluorouracil Fluorouracil results in increased expression of BIRC5 mRNA; Fluorouracil results in increased expression of BIRC5 protein Fluorouracil results in decreased expression of BIRC5 mRNA; Fluorouracil results in decreased expression of BIRC5 protein [Fluorouracil co-treated with RNF34 protein] results in increased expression of BIRC5 protein; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BIRC5 mRNA; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 protein]; SM-1 compound inhibits the reaction [Fluorouracil results in increased expression of BIRC5 mRNA]; SM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BIRC5 protein] BIRC5 affects the susceptibility to Fluorouracil; BIRC5 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15067352 PMID:15109396 PMID:15685548 PMID:16217747 PMID:16546719 PMID:16596200 PMID:16709241 PMID:16929163 PMID:17399942 PMID:18714155 PMID:19618606 PMID:28599477 PMID:29054700 More...
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Birc6 |
baculoviral IAP repeat-containing 6 |
affects response to substance decreases response to substance |
ISO |
BIRC6 protein affects the susceptibility to Fluorouracil BIRC6 results in decreased susceptibility to Fluorouracil |
CTD |
PMID:18239605 PMID:21542283 |
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NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434
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G |
Birc7 |
baculoviral IAP repeat-containing 7 |
decreases response to substance |
ISO |
BIRC7 protein results in decreased susceptibility to Fluorouracil |
CTD |
PMID:17437058 |
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NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606
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G |
Blm |
BLM RecQ like helicase |
decreases expression |
ISO |
Fluorouracil results in decreased expression of BLM mRNA |
CTD |
PMID:19272435 |
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NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
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G |
Blvrb |
biliverdin reductase B |
affects response to substance |
ISO |
BLVRB protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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G |
Bnip1 |
BCL2 interacting protein 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of BNIP1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr10:16,386,876...16,399,124
Ensembl chr10:16,386,841...16,399,157
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G |
Bnip3 |
BCL2 interacting protein 3 |
multiple interactions affects response to substance |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of BNIP3 mRNA] BNIP3 affects the susceptibility to Fluorouracil |
CTD |
PMID:15016801 PMID:15067352 |
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NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Bnip3l |
BCL2 interacting protein 3 like |
affects response to substance decreases expression increases expression |
ISO |
BNIP3L affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of BNIP3L mRNA Fluorouracil results in increased expression of BNIP3L mRNA |
CTD |
PMID:15067352 PMID:15109396 PMID:16557594 PMID:16709241 PMID:17039268 |
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NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
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G |
Boll |
boule homolog, RNA binding protein |
multiple interactions |
ISO |
BOLL mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] |
CTD |
PMID:17327601 |
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NCBI chr 9:56,734,890...56,859,917
Ensembl chr 9:56,733,584...56,859,916
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G |
Bop1 |
BOP1 ribosomal biogenesis factor |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of BOP1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931
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G |
Bora |
bora, aurora kinase A activator |
decreases expression |
ISO |
Fluorouracil results in decreased expression of BORA mRNA |
CTD |
PMID:17374387 |
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NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
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G |
Brca1 |
BRCA1, DNA repair associated |
increases expression decreases expression multiple interactions |
ISO |
Fluorouracil results in increased expression of BRCA1 mRNA Fluorouracil results in decreased expression of BRCA1 mRNA TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of BRCA1 mRNA] |
CTD |
PMID:15607317 PMID:16101138 PMID:16557594 PMID:17982676 |
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NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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G |
Brix1 |
biogenesis of ribosomes BRX1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of BRIX1 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 2:59,450,608...59,461,486
Ensembl chr 2:59,450,614...59,461,495
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G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression multiple interactions |
ISO |
Fluorouracil results in increased expression of BTG2 mRNA TP53 protein affects the reaction [Fluorouracil results in increased expression of BTG2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of BTG2 mRNA] |
CTD |
PMID:15016801 PMID:17982676 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
Btg3 |
BTG anti-proliferation factor 3 |
multiple interactions |
ISO |
BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] |
CTD |
PMID:16896004 |
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NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
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G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
decreases expression |
ISO |
Fluorouracil results in decreased expression of BUB1 mRNA |
CTD |
PMID:16709241 PMID:19272435 |
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NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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G |
Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
decreases expression |
ISO |
Fluorouracil results in decreased expression of BUB1B mRNA |
CTD |
PMID:16557594 PMID:16709241 PMID:19272435 |
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NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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G |
Bub3 |
BUB3 mitotic checkpoint protein |
affects response to substance decreases expression |
ISO |
BUB3 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of BUB3 protein |
CTD |
PMID:15548681 PMID:15585135 PMID:16803524 |
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NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036
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G |
C10h1orf35 |
similar to human chromosome 1 open reading frame 35 |
affects expression |
ISO |
Fluorouracil affects the expression of C1ORF35 mRNA |
CTD |
PMID:16584549 |
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NCBI chr10:43,993,809...43,997,287
Ensembl chr10:43,993,668...43,997,289
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G |
C1h11orf24 |
similar to human chromosome 11 open reading frame 24 |
affects response to substance |
ISO |
C11ORF24 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 1:200,945,188...200,953,953
Ensembl chr 1:200,945,180...200,962,585
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G |
C4bpb |
complement component 4 binding protein, beta |
affects expression |
ISO |
Fluorouracil affects the expression of C4BPB mRNA |
CTD |
PMID:16584549 |
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NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817
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G |
C6h14orf132 |
similar to human chromosome 14 open reading frame 132 |
increases expression |
ISO |
Fluorouracil results in increased expression of C14ORF132 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 6:124,365,466...124,398,449
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G |
Cabyr |
calcium binding tyrosine phosphorylation regulated |
affects response to substance |
ISO |
CABYR protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr18:3,892,062...3,904,391
Ensembl chr18:3,892,132...3,903,840
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G |
Cad |
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CAD mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861
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G |
Calb2 |
calbindin 2 |
increases response to substance increases expression |
ISO |
CALB2 protein results in increased susceptibility to Fluorouracil Fluorouracil results in increased expression of CALB2 mRNA |
CTD |
PMID:16510598 |
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NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
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G |
Canx |
calnexin |
multiple interactions |
ISO |
CANX results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CANX mRNA] |
CTD |
PMID:15016801 PMID:18678097 |
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NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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G |
Cap2 |
cyclase associated actin cytoskeleton regulatory protein 2 |
affects response to substance |
ISO |
CAP2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373
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G |
Car12 |
carbonic anhydrase 12 |
multiple interactions |
ISO |
CA12 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] |
CTD |
PMID:16896004 |
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NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
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G |
Car14 |
carbonic anhydrase 14 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CA14 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693
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G |
Casd1 |
CAS1 domain containing 1 |
affects expression |
ISO |
Fluorouracil affects the expression of CASD1 mRNA |
CTD |
PMID:20421339 |
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NCBI chr 4:32,659,196...32,739,228
Ensembl chr 4:32,658,748...32,739,202
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G |
Casp1 |
caspase 1 |
increases cleavage |
ISO |
Fluorouracil results in increased cleavage of CASP1 protein |
CTD |
PMID:15162350 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp2 |
caspase 2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CASP2 mRNA |
CTD |
PMID:34151400 |
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NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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G |
Casp3 |
caspase 3 |
increases expression increases cleavage affects expression multiple interactions increases activity decreases cleavage decreases expression |
ISO EXP |
Fluorouracil results in increased expression of CASP3; Fluorouracil results in increased expression of CASP3 mRNA; Fluorouracil results in increased expression of CASP3 protein; Fluorouracil results in increased expression of CASP3 protein modified form Fluorouracil results in increased cleavage of CASP3 protein Fluorouracil affects the expression of CASP3 mRNA [diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in decreased cleavage of CASP3 protein]; Bosentan inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; Silybin inhibits the reaction [Fluorouracil results in increased expression of CASP3 protein] Fluorouracil results in increased activity of CASP3 protein Fluorouracil results in decreased cleavage of CASP3 protein 3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein]; [10-hydroxycamptothecin co-treated with Fluorouracil co-treated with Leucovorin] results in increased activity of CASP3 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 protein; [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP3 protein; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP3; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP3 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP3 protein; [Fluorouracil co-treated with IFNB1 protein] results in increased activity of CASP3 protein; [Fluorouracil co-treated with olaparib] results in increased cleavage of CASP3 protein; [Fluorouracil co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased activity of CASP3 protein; [SM-1 compound co-treated with Fluorouracil] results in increased cleavage of CASP3 protein; [wogonin co-treated with Fluorouracil] results in increased activity of CASP3 protein; Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]]; Celecoxib inhibits the reaction [Fluorouracil results in increased expression of CASP3 protein]; chan-yu-bao-yuan-tang promotes the reaction [Fluorouracil results in increased cleavage of and results in increased expression of CASP3 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP3 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [chan-yu-bao-yuan-tang results in increased cleavage of and results in increased expression of CASP3 protein]; Fluorouracil promotes the reaction [gambogic acid results in decreased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [temsirolimus results in increased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP3 protein]; Fluorouracil results in increased activity of and results in increased cleavage of CASP3 protein; Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein; Fluorouracil results in increased cleavage of and results in increased expression of CASP3 protein; HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFI6 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [Fluorouracil results in decreased cleavage of CASP3 protein]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CASP3 mRNA]; temsirolimus promotes the reaction [Fluorouracil results in increased expression of CASP3 mRNA]; TNFRSF10B mutant form inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein] Fluorouracil results in decreased expression of CASP3 mRNA 3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein]; Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; casticin inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [Apigenin results in increased activity of CASP3 protein]; Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein; IL1RN protein affects the reaction [Fluorouracil results in increased expression of CASP3 protein modified form] |
CTD |
PMID:10891390 PMID:11300326 PMID:12414664 PMID:12934351 PMID:12941601 PMID:14503796 PMID:15120327 PMID:15282376 PMID:15585135 PMID:15685448 PMID:16080519 PMID:16168113 PMID:16407826 PMID:16803524 PMID:17016659 PMID:17056233 PMID:17219956 PMID:17399942 PMID:17461495 PMID:17498489 PMID:17589894 PMID:18161298 PMID:18205257 PMID:18608205 PMID:18772588 PMID:18830594 PMID:19084572 PMID:19097688 PMID:19116755 PMID:19764996 PMID:19815060 PMID:19816940 PMID:19885610 PMID:19928967 PMID:20570612 PMID:20844880 PMID:20876774 PMID:21036698 PMID:21461573 PMID:25940438 PMID:26310874 PMID:26544897 PMID:28025107 PMID:28599477 PMID:29678497 PMID:31129132 PMID:31288002 PMID:32270916 PMID:32634519 PMID:32800223 PMID:34151400 PMID:34794354 PMID:34800596 PMID:36203040 PMID:37335224 PMID:37625625 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
increases expression affects response to substance |
ISO |
Fluorouracil results in increased expression of CASP4 protein CASP4 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 PMID:16217747 |
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NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp6 |
caspase 6 |
multiple interactions affects expression |
ISO |
Fluorouracil results in increased cleavage of and results in increased activity of CASP6 protein; resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]; TP53 affects the reaction [resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]] Fluorouracil affects the expression of CASP6 mRNA |
CTD |
PMID:18497562 PMID:34151400 |
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NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp7 |
caspase 7 |
multiple interactions increases expression increases cleavage |
ISO |
[Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 protein Fluorouracil results in increased expression of CASP7 mRNA Fluorouracil results in increased cleavage of CASP7 protein |
CTD |
PMID:16168113 PMID:26544897 PMID:34151400 |
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NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions increases activity increases cleavage decreases expression increases expression |
ISO |
[Cadmium Chloride co-treated with Fluorouracil] affects the expression of CASP8 protein; [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP8 protein; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP8; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP8 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP8 protein; [Fluorouracil co-treated with olaparib] results in increased cleavage of CASP8 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased cleavage of CASP8 protein]; Cadmium Chloride affects the reaction [Fluorouracil results in decreased expression of CASP8 mRNA]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]]; CASP8 results in increased susceptibility to [andrographolide co-treated with Fluorouracil]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP8 protein]; Fluorouracil affects the reaction [Cadmium Chloride results in decreased expression of CASP8 mRNA]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP8 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP8 protein]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP8 protein]; IFNA1 promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP8 protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Fluorouracil results in increased activity of CASP8 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 protein] Fluorouracil results in increased cleavage of CASP8 protein Fluorouracil results in increased expression of CASP8 mRNA; Fluorouracil results in increased expression of CASP8 protein |
CTD |
PMID:10779637 PMID:10891390 PMID:12414664 PMID:14607657 PMID:15585135 PMID:16168113 PMID:16803524 PMID:17016659 PMID:17056233 PMID:17637740 PMID:18830594 PMID:19097688 PMID:19816940 PMID:19928967 PMID:20876774 PMID:21474236 PMID:23941782 PMID:26544897 PMID:32270916 PMID:34151400 More...
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases activity decreases expression increases expression increases cleavage |
ISO EXP |
[Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of CASP9 mRNA; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP9; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP9 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP9 protein; Cadmium Chloride promotes the reaction [Fluorouracil results in decreased expression of CASP9 mRNA]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP9 protein]; Fluorouracil inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 mRNA]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP9 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [Arsenic Trioxide results in decreased expression of CASP9 protein]; Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]; TP53 protein inhibits the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]] Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein] Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; casticin promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [Apigenin results in increased activity of CASP9 protein] Fluorouracil results in increased expression of CASP9 protein Fluorouracil results in increased cleavage of CASP9 protein |
CTD |
PMID:10779637 PMID:12414664 PMID:15546879 PMID:15996812 PMID:16168113 PMID:16407826 PMID:16803524 PMID:17016659 PMID:17056233 PMID:17498489 PMID:18830594 PMID:19015929 PMID:19097688 PMID:19816940 PMID:19928967 PMID:22963400 PMID:23941782 PMID:28025107 PMID:31129132 PMID:32270916 More...
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions decreases expression decreases activity |
ISO EXP |
Fluorouracil inhibits the reaction [casticin results in increased expression of CAT protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Fluorouracil promotes the reaction [Luteolin results in decreased activity of CAT protein]; Fluorouracil promotes the reaction [Valsartan results in decreased activity of CAT protein]; Luteolin promotes the reaction [Fluorouracil results in decreased activity of CAT protein]; Valsartan promotes the reaction [Fluorouracil results in decreased activity of CAT protein] Fluorouracil results in decreased expression of CAT protein Silybin inhibits the reaction [Fluorouracil results in decreased expression of CAT protein] [Fluorouracil co-treated with Arsenic Trioxide] results in decreased activity of CAT protein |
CTD |
PMID:27836789 PMID:29117755 PMID:31288002 PMID:32270916 PMID:32752303 PMID:33634982 PMID:35235860 PMID:37335224 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
affects response to substance increases expression decreases expression |
ISO |
CAV1 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CAV1 mRNA Fluorouracil results in decreased expression of CAV1 protein |
CTD |
PMID:15352031 PMID:24737281 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cav2 |
caveolin 2 |
decreases expression increases expression |
ISO |
Fluorouracil results in decreased expression of CAV2 mRNA Fluorouracil results in increased expression of CAV2 mRNA |
CTD |
PMID:16510598 PMID:24737281 |
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NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
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G |
Cbr3 |
carbonyl reductase 3 |
affects expression |
ISO |
Fluorouracil affects the expression of CBR3 mRNA |
CTD |
PMID:20421339 |
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NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
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G |
Cbs |
cystathionine beta synthase |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CBS mRNA] |
CTD |
PMID:15016801 |
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NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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G |
Cbx1 |
chromobox 1 |
affects response to substance |
ISO |
CBX1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
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G |
Ccdc186 |
coiled-coil domain containing 186 |
increases expression |
ISO |
Fluorouracil results in increased expression of CCDC186 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 1:255,831,663...255,871,954
Ensembl chr 1:255,839,595...255,871,935
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of CCL2 mRNA Fluorouracil promotes the reaction [Valsartan results in decreased expression of CCL2 mRNA]; Valsartan promotes the reaction [Fluorouracil results in decreased expression of CCL2 mRNA] |
CTD |
PMID:35235860 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccn1 |
cellular communication network factor 1 |
increases expression affects response to substance |
ISO |
Fluorouracil results in increased expression of CCN1 mRNA; Fluorouracil results in increased expression of CCN1 protein CCN1 affects the susceptibility to Fluorouracil |
CTD |
PMID:15067352 PMID:17699798 PMID:24737281 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
affects expression |
ISO |
Fluorouracil affects the expression of CCN2 mRNA |
CTD |
PMID:15205334 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccn3 |
cellular communication network factor 3 |
increases expression |
ISO |
Fluorouracil results in increased expression of CCN3 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
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G |
Ccna1 |
cyclin A1 |
multiple interactions affects expression |
ISO |
[Cadmium Chloride co-treated with Fluorouracil] affects the expression of CCNA1 protein; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of CCNA1 mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of CCNA1 mRNA] Fluorouracil affects the expression of CCNA1 mRNA; Fluorouracil affects the expression of CCNA1 protein |
CTD |
PMID:23941782 |
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NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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G |
Ccna2 |
cyclin A2 |
multiple interactions affects response to substance affects expression decreases expression |
ISO |
N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNA2 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]] CCNA2 protein affects the susceptibility to Fluorouracil Fluorouracil affects the expression of CCNA2 mRNA Fluorouracil results in decreased expression of CCNA2 mRNA; Fluorouracil results in decreased expression of CCNA2 protein |
CTD |
PMID:15205334 PMID:15546879 PMID:15548681 PMID:16557594 PMID:18383818 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
multiple interactions decreases expression |
ISO |
N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]] Fluorouracil results in decreased expression of CCNB1 mRNA; Fluorouracil results in decreased expression of CCNB1 protein |
CTD |
PMID:15016801 PMID:15205334 PMID:15546879 PMID:16557594 PMID:17982676 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb2 |
cyclin B2 |
multiple interactions decreases expression |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB2 mRNA] Fluorouracil results in decreased expression of CCNB2 mRNA; Fluorouracil results in decreased expression of CCNB2 protein |
CTD |
PMID:15016801 PMID:16557594 PMID:16709241 PMID:17982488 PMID:19272435 |
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NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnc |
cyclin C |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CCNC mRNA |
CTD |
PMID:16709241 |
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NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
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G |
Ccnd1 |
cyclin D1 |
affects response to substance multiple interactions decreases expression affects expression |
ISO |
CCND1 protein affects the susceptibility to Fluorouracil Fluorouracil promotes the reaction [Luteolin results in decreased expression of CCND1 protein]; Luteolin promotes the reaction [Fluorouracil results in decreased expression of CCND1 protein] Fluorouracil affects the expression of CCND1 mRNA; Fluorouracil affects the expression of CCND1 protein Fluorouracil results in decreased expression of CCND1 mRNA; Fluorouracil results in decreased expression of CCND1 protein [allose co-treated with Fluorouracil] results in decreased expression of CCND1 protein; [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CCND1 protein; [Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCND1 mRNA; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of CCND1 mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of CCND1 mRNA]; Fluorouracil promotes the reaction [allose results in decreased expression of CCND1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCND1 protein] |
CTD |
PMID:15352031 PMID:17982676 PMID:18930000 PMID:23941782 PMID:31288002 PMID:31587439 More...
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
increases expression decreases expression multiple interactions affects response to substance |
ISO |
Fluorouracil results in increased expression of CCND2 protein Fluorouracil results in decreased expression of CCND2 mRNA TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCND2 mRNA] CCND2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15016801 PMID:15352031 PMID:19272435 |
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NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Ccnd3 |
cyclin D3 |
affects response to substance increases expression |
ISO |
CCND3 affects the susceptibility to Fluorouracil; CCND3 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CCND3 mRNA |
CTD |
PMID:15067352 PMID:15548681 PMID:16709241 PMID:18383818 |
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NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne1 |
cyclin E1 |
decreases expression multiple interactions increases expression |
ISO |
Fluorouracil results in decreased expression of CCNE1 mRNA [Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCNE1 mRNA; [Leucovorin co-treated with Fluorouracil] results in increased expression of CCNE1 mRNA Fluorouracil results in increased expression of CCNE1 mRNA; Fluorouracil results in increased expression of CCNE1 protein |
CTD |
PMID:9930367 PMID:15342418 PMID:16101138 PMID:18930000 PMID:31587439 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccne2 |
cyclin E2 |
affects response to substance |
ISO |
CCNE2 affects the susceptibility to Fluorouracil |
CTD |
PMID:15067352 |
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NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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G |
Ccnf |
cyclin F |
affects response to substance |
ISO |
CCNF affects the susceptibility to Fluorouracil |
CTD |
PMID:15067352 |
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NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
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G |
Ccng1 |
cyclin G1 |
affects response to substance increases expression multiple interactions decreases expression |
ISO |
CCNG1 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CCNG1 mRNA TP53 protein promotes the reaction [Fluorouracil results in increased expression of CCNG1 mRNA] Fluorouracil results in decreased expression of CCNG1 mRNA |
CTD |
PMID:15152939 PMID:16217747 PMID:16557594 PMID:16709241 PMID:17982676 PMID:19272435 PMID:22525470 More...
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NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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G |
Ccng2 |
cyclin G2 |
affects response to substance decreases expression increases expression |
ISO |
CCNG2 affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CCNG2 mRNA Fluorouracil results in increased expression of CCNG2 mRNA |
CTD |
PMID:15067352 PMID:16510598 PMID:16557594 PMID:17039268 PMID:18754885 PMID:19272435 More...
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NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
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G |
Ccnjl |
cyclin J-like |
affects expression |
ISO |
Fluorouracil affects the expression of CCNJL mRNA |
CTD |
PMID:16584549 |
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NCBI chr10:27,995,682...28,053,428
Ensembl chr10:27,995,679...28,053,426
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G |
Cd109 |
CD109 molecule |
affects response to substance |
ISO |
CD109 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:37661780 |
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NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
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G |
Cd24 |
CD24 molecule |
increases expression |
ISO |
Fluorouracil results in increased expression of CD24 mRNA |
CTD |
PMID:16510598 |
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NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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G |
Cd274 |
CD274 molecule |
increases expression |
ISO |
Fluorouracil results in increased expression of CD274 protein |
CTD |
PMID:17920123 |
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NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
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G |
Cd34 |
CD34 molecule |
increases expression |
ISO |
Fluorouracil results in increased expression of CD34 protein |
CTD |
PMID:21296659 |
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NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
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G |
Cd38 |
CD38 molecule |
affects expression |
ISO |
Fluorouracil affects the expression of CD38 mRNA |
CTD |
PMID:16584549 |
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NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
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G |
Cd40 |
CD40 molecule |
decreases response to substance multiple interactions |
ISO |
CD40 results in decreased susceptibility to Fluorouracil Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] |
CTD |
PMID:15611226 PMID:20188757 |
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NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd40lg |
CD40 ligand |
multiple interactions |
ISO |
Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] |
CTD |
PMID:15611226 |
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NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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G |
Cd44 |
CD44 molecule |
multiple interactions |
EXP |
[gimeracil co-treated with Fluorouracil] results in decreased expression of CD44 |
CTD |
PMID:12364819 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd52 |
CD52 molecule |
affects expression multiple interactions |
ISO |
Fluorouracil affects the expression of CD52 mRNA TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD52 mRNA] |
CTD |
PMID:15016801 PMID:16584549 |
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NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348
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G |
Cd63 |
Cd63 molecule |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CD63 |
CTD |
PMID:15485462 |
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NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178
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G |
Cd8a |
CD8 subunit alpha |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD8A mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040
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G |
Cd8b |
CD8 subunit beta |
affects response to substance decreases expression |
ISO |
CD8B protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CD8B protein |
CTD |
PMID:15352031 |
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NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
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G |
Cd9 |
CD9 molecule |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CD9 protein |
CTD |
PMID:21296659 |
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NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
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G |
Cda |
cytidine deaminase |
multiple interactions |
EXP |
[CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Fluorouracil |
CTD |
PMID:10811482 |
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NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
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G |
Cdc20 |
cell division cycle 20 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDC20 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc25a |
cell division cycle 25A |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CDC25A mRNA |
CTD |
PMID:16510598 |
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NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
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G |
Cdc25b |
cell division cycle 25B |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CDC25B mRNA |
CTD |
PMID:16709241 PMID:19272435 |
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NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
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G |
Cdc25c |
cell division cycle 25C |
affects response to substance decreases expression |
ISO |
CDC25C protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CDC25C mRNA |
CTD |
PMID:15548681 PMID:19272435 |
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NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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G |
Cdc34 |
cell division cycle 34, ubiqiutin conjugating enzyme |
affects response to substance |
ISO |
CDC34 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186
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G |
Cdc40 |
cell division cycle 40 |
increases expression |
ISO |
Fluorouracil results in increased expression of CDC40 protein |
CTD |
PMID:16803524 |
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NCBI chr20:44,273,080...44,325,605
Ensembl chr20:44,273,089...44,325,358
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G |
Cdc42ep1 |
CDC42 effector protein 1 |
affects response to substance |
ISO |
CDC42EP1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200
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G |
Cdc45 |
cell division cycle 45 |
multiple interactions decreases expression affects expression |
ISO |
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDC45 mRNA Fluorouracil results in decreased expression of CDC45 mRNA Fluorouracil affects the expression of CDC45 mRNA |
CTD |
PMID:15342418 PMID:16557594 PMID:19272435 |
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NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
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G |
Cdc6 |
cell division cycle 6 |
affects expression decreases expression multiple interactions increases expression |
ISO |
Fluorouracil affects the expression of CDC6 mRNA Fluorouracil results in decreased expression of CDC6 mRNA [Leucovorin co-treated with Fluorouracil] results in increased expression of CDC6 mRNA Fluorouracil results in increased expression of CDC6 mRNA |
CTD |
PMID:15342418 PMID:16557594 PMID:16709241 PMID:17039268 PMID:19272435 |
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NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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G |
Cdc73 |
cell division cycle 73 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CDC73 mRNA |
CTD |
PMID:16510598 |
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NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
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G |
Cdca5 |
cell division cycle associated 5 |
increases expression |
ISO |
Fluorouracil results in increased expression of CDCA5 mRNA |
CTD |
PMID:16709241 |
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NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
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G |
Cdca7 |
cell division cycle associated 7 |
affects expression |
ISO |
Fluorouracil affects the expression of CDCA7 mRNA |
CTD |
PMID:20421339 |
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NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
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G |
Cdca8 |
cell division cycle associated 8 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CDCA8 mRNA |
CTD |
PMID:17374387 |
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NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
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G |
Cdh1 |
cadherin 1 |
affects response to substance decreases expression multiple interactions |
ISO |
CDH1 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CDH1 protein resveratrol inhibits the reaction [Fluorouracil results in decreased expression of CDH1 protein] |
CTD |
PMID:15352031 PMID:26310874 |
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh5 |
cadherin 5 |
increases expression multiple interactions |
ISO |
Fluorouracil results in increased expression of CDH5 protein Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein] |
CTD |
PMID:21296659 PMID:31404653 |
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NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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G |
Cdh6 |
cadherin 6 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CDH6 mRNA |
CTD |
PMID:24737281 |
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NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228
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G |
Cdipt |
CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
affects expression |
ISO |
Fluorouracil affects the expression of CDIPT mRNA |
CTD |
PMID:16584549 |
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NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression multiple interactions increases expression affects expression |
ISO |
Fluorouracil results in decreased expression of CDK1 mRNA [Leucovorin co-treated with Fluorouracil] results in increased expression of CDK1 mRNA Fluorouracil results in increased expression of CDK1 mRNA Fluorouracil affects the expression of CDK1 mRNA |
CTD |
PMID:15152939 PMID:15205334 PMID:15342418 PMID:16557594 PMID:17039268 PMID:26272751 More...
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk2 |
cyclin dependent kinase 2 |
affects response to substance multiple interactions increases expression |
ISO |
CDK2 protein affects the susceptibility to Fluorouracil; CDK2 protein modified form affects the susceptibility to Fluorouracil [Leucovorin co-treated with Fluorouracil] results in increased expression of CDK2 mRNA Fluorouracil results in increased expression of CDK2 mRNA |
CTD |
PMID:15342418 PMID:15548681 PMID:16557594 PMID:18383818 |
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NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk5r1 |
cyclin-dependent kinase 5 regulatory subunit 1 |
affects expression |
ISO |
Fluorouracil affects the expression of CDK5R1 mRNA |
CTD |
PMID:15205334 |
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NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
affects response to substance multiple interactions increases expression decreases degradation decreases expression decreases response to substance increases response to substance |
ISO |
CDKN1A affects the susceptibility to Fluorouracil; CDKN1A protein affects the susceptibility to Fluorouracil Fluorouracil promotes the reaction [Luteolin results in increased expression of CDKN1A protein]; Luteolin promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein] Fluorouracil results in increased expression of CDKN1A mRNA; Fluorouracil results in increased expression of CDKN1A protein Fluorouracil results in increased expression of CDKN1A; Fluorouracil results in increased expression of CDKN1A mRNA; Fluorouracil results in increased expression of CDKN1A protein Fluorouracil results in decreased degradation of CDKN1A protein Fluorouracil results in decreased expression of CDKN1A protein [Fluorouracil co-treated with Genistein] results in increased expression of CDKN1A mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in increased expression of CDKN1A protein; [Fluorouracil co-treated with Plant Extracts] results in increased expression of CDKN1A protein; [Leucovorin co-treated with Fluorouracil] results in increased expression of CDKN1A mRNA; CDKN1A protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; CDKN1A protein affects the reaction [Fluorouracil results in decreased expression of UBE2C protein]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of CDKN1A protein]; Fluorouracil promotes the reaction [[TP53 protein binds to SP1 protein] which binds to CDKN1A promoter]; Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CDKN1A mRNA]; Fluorouracil promotes the reaction [temsirolimus results in increased expression of CDKN1A mRNA]; mithramycin A inhibits the reaction [Fluorouracil results in increased expression of CDKN1A protein]; Pravastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein]; Simvastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; temsirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein] CDKN1A protein results in decreased susceptibility to Fluorouracil CDKN1A protein results in increased susceptibility to Fluorouracil |
CTD |
PMID:14646558 PMID:14665630 PMID:15016801 PMID:15067352 PMID:15205334 PMID:15331170 PMID:15342418 PMID:15375580 PMID:15489892 PMID:15546879 PMID:15625077 PMID:15754201 PMID:15896711 PMID:16168113 PMID:16434701 PMID:16557594 PMID:16584549 PMID:16686938 PMID:16709241 PMID:16949053 PMID:17039268 PMID:17207318 PMID:17355264 PMID:17699798 PMID:17982676 PMID:18834353 PMID:19098008 PMID:19764996 PMID:24211769 PMID:27129209 PMID:27163855 PMID:31288002 More...
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
affects response to substance decreases expression |
ISO |
CDKN1B protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CDKN1B mRNA |
CTD |
PMID:17217824 PMID:18930000 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
affects response to substance increases expression |
ISO |
CDKN1C affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CDKN1C mRNA |
CTD |
PMID:15067352 PMID:19272435 |
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NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CDKN2A protein |
CTD |
PMID:17982676 |
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NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdkn2aip |
CDKN2A interacting protein |
affects response to substance |
ISO |
CDKN2AIP protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
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G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CDKN2C mRNA |
CTD |
PMID:16557594 |
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NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
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G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDKN3 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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G |
Cdx2 |
caudal type homeo box 2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CDX2 protein Fluorouracil results in decreased expression of CDX2 mRNA |
CTD |
PMID:21296659 PMID:24737281 |
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NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
ISO |
Fluorouracil results in increased expression of CEBPB mRNA |
CTD |
PMID:16557594 PMID:16584549 PMID:34151400 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cenpq |
centromere protein Q |
affects response to substance increases expression |
ISO |
CENPQ protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CENPQ mRNA |
CTD |
PMID:15331170 |
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NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:19,957,048...19,972,789
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G |
Cenpu |
centromere protein U |
affects response to substance |
ISO |
CENPU protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
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G |
Cenpx |
centromere protein X |
affects response to substance |
ISO |
CENPX protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr10:105,991,469...105,994,310
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G |
Cep55 |
centrosomal protein 55 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CEP55 mRNA |
CTD |
PMID:17039268 |
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NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
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G |
Cer1 |
cerberus 1, DAN family BMP antagonist |
increases expression decreases expression |
ISO |
Fluorouracil results in increased expression of CER1 mRNA Fluorouracil results in decreased expression of CER1 mRNA |
CTD |
PMID:24737281 PMID:26272751 |
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NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
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G |
Ces2h |
carboxylesterase 2H |
multiple interactions increases expression |
ISO |
Fluorouracil promotes the reaction [TP53 protein binds to CES2 intron]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CES2 mRNA] |
CTD |
PMID:15205334 PMID:16963839 PMID:17287894 |
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NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
multiple interactions affects response to substance decreases expression increases expression |
ISO |
[Fluorouracil co-treated with IFNA1 protein] results in decreased expression of CFLAR protein; [Fluorouracil results in decreased expression of CFLAR protein] which results in increased susceptibility to TNFSF10 protein; CFLAR protein alternative form inhibits the reaction [Fluorouracil results in increased activity of TNFSF10 protein]; CFLAR protein inhibits the reaction [Fluorouracil results in increased susceptibility to TNFSF10 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of CFLAR mRNA] CFLAR protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CFLAR mRNA; Fluorouracil results in decreased expression of CFLAR protein Fluorouracil results in increased expression of CFLAR mRNA |
CTD |
PMID:15152939 PMID:15548681 PMID:16217747 PMID:16373718 PMID:17045692 PMID:20876774 More...
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NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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G |
Chek1 |
checkpoint kinase 1 |
affects response to substance decreases expression increases expression multiple interactions |
ISO |
CHEK1 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CHEK1 mRNA Fluorouracil results in increased expression of CHEK1 protein [CHEK1 protein co-treated with TP53 protein] affects the susceptibility to Fluorouracil; Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK1 protein; TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Fluorouracil]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHEK1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of CHEK1 protein] |
CTD |
PMID:15016801 PMID:18698031 PMID:19272435 PMID:21613406 PMID:22194930 |
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NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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G |
Chek2 |
checkpoint kinase 2 |
multiple interactions |
ISO |
Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK2 protein |
CTD |
PMID:21613406 |
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NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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G |
Chi3l1 |
chitinase 3 like 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of CHI3L1 mRNA |
CTD |
PMID:15205334 |
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NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHRNA4 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
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G |
Chst7 |
carbohydrate sulfotransferase 7 |
affects response to substance |
ISO |
CHST7 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr X:2,396,260...2,432,828
Ensembl chr X:2,393,874...2,432,840
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G |
Ciao1 |
cytosolic iron-sulfur assembly component 1 |
affects response to substance |
ISO |
CIAO1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr 3:114,458,671...114,465,928
Ensembl chr 3:114,458,655...114,467,009
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G |
Cideb |
cell death-inducing DFFA-like effector b |
increases expression |
ISO |
Fluorouracil results in increased expression of CIDEB protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr15:29,252,208...29,256,482
Ensembl chr15:29,252,213...29,256,605
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G |
Cited2 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
affects response to substance |
ISO |
CITED2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
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G |
Ckb |
creatine kinase B |
affects response to substance |
ISO |
CKB protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Cks2 |
CDC28 protein kinase regulatory subunit 2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CKS2 mRNA |
CTD |
PMID:17374387 PMID:19272435 |
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NCBI chr17:13,570,611...13,575,770
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G |
Clcn3 |
chloride voltage-gated channel 3 |
affects response to substance |
ISO |
CLCN3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
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G |
Cldn2 |
claudin 2 |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of CLDN2 protein resveratrol inhibits the reaction [Fluorouracil results in decreased expression of CLDN2 protein] |
CTD |
PMID:26310874 |
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NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838
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G |
Cldn4 |
claudin 4 |
affects response to substance decreases expression |
ISO |
CLDN4 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CLDN4 protein |
CTD |
PMID:15352031 |
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NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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G |
Clec11a |
C-type lectin domain containing 11A |
affects response to substance decreases expression |
ISO |
CLEC11A protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CLEC11A protein |
CTD |
PMID:15352031 |
|
NCBI chr 1:94,800,456...94,809,002
Ensembl chr 1:94,801,496...94,804,633
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G |
Clic1 |
chloride intracellular channel 1 |
affects response to substance |
ISO |
CLIC1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
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G |
Cltc |
clathrin heavy chain |
multiple interactions |
ISO |
CLTC protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CLTC mRNA] |
CTD |
PMID:15016801 PMID:18927307 |
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NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
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G |
Coch |
cochlin |
affects response to substance |
ISO |
COCH protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109
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G |
Col12a1 |
collagen type XII alpha 1 chain |
decreases expression |
ISO |
Fluorouracil results in decreased expression of COL12A1 mRNA |
CTD |
PMID:15205334 PMID:16510598 |
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NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
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G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of COL1A1 mRNA; Fluorouracil results in decreased expression of COL1A1 protein Fluorouracil promotes the reaction [Valsartan results in decreased expression of COL1A1 mRNA]; Valsartan promotes the reaction [Fluorouracil results in decreased expression of COL1A1 mRNA] |
CTD |
PMID:21296659 PMID:35235860 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
affects expression |
ISO |
Fluorouracil affects the expression of COL1A2 mRNA |
CTD |
PMID:24704097 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col2a1 |
collagen type II alpha 1 chain |
decreases expression |
ISO |
Fluorouracil results in decreased expression of COL2A1 protein Fluorouracil results in decreased expression of COL2A1 mRNA |
CTD |
PMID:21296659 PMID:24737281 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
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G |
Col3a1 |
collagen type III alpha 1 chain |
affects response to substance |
ISO |
COL3A1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col4a2 |
collagen type IV alpha 2 chain |
affects response to substance decreases expression |
ISO |
COL4A2 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of COL4A2 protein |
CTD |
PMID:15352031 |
|
NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
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G |
Col5a2 |
collagen type V alpha 2 chain |
affects response to substance |
ISO |
COL5A2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
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G |
Col6a3 |
collagen type VI alpha 3 chain |
affects response to substance multiple interactions |
ISO |
COL6A3 protein affects the susceptibility to Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of COL6A3 mRNA] |
CTD |
PMID:15016801 PMID:16217747 |
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NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471
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G |
Cox14 |
cytochrome c oxidase assembly factor COX14 |
affects expression |
ISO |
Fluorouracil affects the expression of COX14 mRNA |
CTD |
PMID:34151400 |
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NCBI chr 7:130,852,226...130,854,316
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G |
Cox5b |
cytochrome c oxidase subunit 5B |
affects expression |
ISO |
Fluorouracil affects the expression of COX5B mRNA |
CTD |
PMID:34151400 |
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NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
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G |
Cox6c |
cytochrome c oxidase subunit 6C |
affects expression |
ISO |
Fluorouracil affects the expression of COX6C mRNA |
CTD |
PMID:34151400 |
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NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963
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G |
Cox7c |
cytochrome c oxidase subunit 7C |
affects expression |
ISO |
Fluorouracil affects the expression of COX7C mRNA |
CTD |
PMID:34151400 |
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NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
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G |
Cp |
ceruloplasmin |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CP mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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G |
Cpa4 |
carboxypeptidase A4 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CPA4 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 4:59,188,284...59,212,255
Ensembl chr 4:59,188,284...59,212,255
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G |
Cpd |
carboxypeptidase D |
affects response to substance multiple interactions |
ISO |
CPD protein affects the susceptibility to Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of CPD mRNA] |
CTD |
PMID:15016801 PMID:16217747 |
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NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491
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G |
Cpe |
carboxypeptidase E |
affects response to substance increases expression |
ISO |
CPE protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CPE protein |
CTD |
PMID:15352031 |
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NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
affects response to substance |
ISO |
CPT1A protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpxm1 |
carboxypeptidase X (M14 family), member 1 |
affects expression |
ISO |
Fluorouracil affects the expression of CPXM1 mRNA |
CTD |
PMID:15205334 |
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NCBI chr 3:117,588,532...117,595,330
Ensembl chr 3:117,588,532...117,595,330
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G |
Crabp1 |
cellular retinoic acid binding protein 1 |
affects response to substance increases expression |
ISO |
CRABP1 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CRABP1 protein |
CTD |
PMID:15352031 |
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NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360
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G |
Crabp2 |
cellular retinoic acid binding protein 2 |
affects expression |
ISO |
Fluorouracil affects the expression of CRABP2 protein |
CTD |
PMID:21296659 |
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NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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G |
Crhbp |
corticotropin releasing hormone binding protein |
affects expression |
ISO |
Fluorouracil affects the expression of CRHBP mRNA |
CTD |
PMID:15205334 |
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NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
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G |
Crim1 |
cysteine rich transmembrane BMP regulator 1 |
affects response to substance increases expression decreases expression |
ISO |
CRIM1 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CRIM1 protein Fluorouracil results in decreased expression of CRIM1 mRNA |
CTD |
PMID:15352031 PMID:16510598 |
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NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
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G |
Cripto |
cripto, EGF-CFC family member |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CRIPTO protein Fluorouracil results in decreased expression of CRIPTO mRNA |
CTD |
PMID:21296659 PMID:24737281 |
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NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308
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G |
Crk |
CRK proto-oncogene, adaptor protein |
affects response to substance |
ISO |
CRK protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
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G |
Crygs |
crystallin, gamma S |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYGS mRNA] |
CTD |
PMID:15016801 |
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NCBI chr11:78,207,170...78,212,273
Ensembl chr11:78,207,170...78,212,273
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G |
Cryl1 |
crystallin, lambda 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYL1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
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G |
Cryz |
crystallin zeta |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of CRYZ mRNA TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CRYZ mRNA] |
CTD |
PMID:17982676 |
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NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
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G |
Cse1l |
chromosome segregation 1 like |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CSE1L mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865
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G |
Csf1 |
colony stimulating factor 1 |
affects response to substance |
ISO |
CSF1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Csf2 |
colony stimulating factor 2 |
increases expression |
ISO |
Fluorouracil results in increased expression of CSF2 mRNA |
CTD |
PMID:18344199 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csnk1e |
casein kinase 1, epsilon |
affects expression |
ISO |
Fluorouracil affects the expression of CSNK1E mRNA |
CTD |
PMID:16584549 |
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NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
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G |
Csrp1 |
cysteine and glycine-rich protein 1 |
affects response to substance |
ISO |
CSRP1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
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G |
Cst7 |
cystatin F |
affects response to substance decreases expression |
ISO |
CST7 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of CST7 protein |
CTD |
PMID:15352031 |
|
NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
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G |
Cst8 |
cystatin 8 |
affects expression |
ISO |
Fluorouracil affects the expression of CST8 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 3:136,244,586...136,255,412
Ensembl chr 3:136,244,636...136,251,273
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G |
Cstf3 |
cleavage stimulation factor subunit 3 |
affects response to substance increases expression |
ISO |
CSTF3 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CSTF3 mRNA |
CTD |
PMID:15331170 |
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NCBI chr 3:90,966,415...91,037,669
Ensembl chr 3:90,966,354...91,042,196
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G |
Ctbp2 |
C-terminal binding protein 2 |
multiple interactions |
ISO |
[Fluorouracil co-treated with irinotecan] results in decreased expression of CTBP2 mRNA; CTBP2 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] |
CTD |
PMID:16391804 PMID:18927307 |
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NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222
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G |
Ctnnd2 |
catenin delta 2 |
multiple interactions |
ISO |
CTNND2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] |
CTD |
PMID:16896004 |
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NCBI chr 2:81,168,525...82,016,495
Ensembl chr 2:81,167,117...82,015,764
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G |
Ctps1 |
CTP synthase 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CTPS1 mRNA |
CTD |
PMID:19219653 |
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NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
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G |
Ctsb |
cathepsin B |
multiple interactions increases cleavage |
ISO |
CA 074 methyl ester inhibits the reaction [Fluorouracil results in increased cleavage of CTSB protein] |
CTD |
PMID:19816940 |
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NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsh |
cathepsin H |
affects response to substance increases expression |
ISO |
CTSH protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of CTSH protein |
CTD |
PMID:15352031 |
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NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
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G |
Cttn |
cortactin |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CTTN protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
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G |
Cul4a |
cullin 4A |
affects response to substance |
ISO |
CUL4A protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16467204 |
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NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
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G |
Cul4b |
cullin 4B |
increases expression |
ISO |
Fluorouracil results in increased expression of CUL4B protein |
CTD |
PMID:16803524 |
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NCBI chr X:117,287,481...117,326,688
Ensembl chr X:117,287,484...117,326,688
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G |
Cul5 |
cullin 5 |
increases expression |
ISO |
Fluorouracil results in increased expression of CUL5 mRNA |
CTD |
PMID:16557594 |
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NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666
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G |
Cutc |
cutC copper transporter |
affects response to substance multiple interactions |
ISO |
CUTC protein affects the susceptibility to Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of CUTC mRNA] |
CTD |
PMID:15016801 PMID:16217747 |
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NCBI chr 1:242,622,281...242,637,048
Ensembl chr 1:242,622,276...242,637,047
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression affects expression |
ISO |
Fluorouracil results in increased expression of CXCL12 mRNA Fluorouracil affects the expression of CXCL12 mRNA |
CTD |
PMID:16337237 PMID:18344199 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Bortezomib inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA] |
CTD |
PMID:27194111 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein]; Bortezomib inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein] Fluorouracil results in increased expression of CXCL1 mRNA; Fluorouracil results in increased expression of CXCL1 protein |
CTD |
PMID:27194111 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
multiple interactions |
ISO |
CXCR1 gene SNP affects the susceptibility to [oxaliplatin co-treated with Fluorouracil] |
CTD |
PMID:16098254 |
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NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
affects expression |
ISO |
Fluorouracil affects the expression of CXCR4 mRNA |
CTD |
PMID:16584549 |
|
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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G |
Cyc1 |
cytochrome c-1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CYC1 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CYCS mRNA |
CTD |
PMID:32800223 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyfip2 |
cytoplasmic FMR1 interacting protein 2 |
affects response to substance multiple interactions increases expression |
ISO |
CYFIP2 protein affects the susceptibility to Fluorouracil TP53 protein affects the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA] |
CTD |
PMID:15016801 PMID:16217747 PMID:17039268 PMID:17982676 |
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NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113
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G |
Cyld |
CYLD lysine 63 deubiquitinase |
increases response to substance |
ISO |
CYLD protein results in increased susceptibility to Fluorouracil |
CTD |
PMID:21109933 |
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NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases metabolic processing |
EXP |
CYP1A1 protein results in increased metabolism of Fluorouracil |
CTD |
PMID:17230597 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
[CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Fluorouracil |
CTD |
PMID:10811482 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2f4 |
cytochrome P450, family 2, subfamily f, polypeptide 4 |
affects expression |
ISO |
Fluorouracil affects the expression of CYP2F1 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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G |
Cyp2s1 |
cytochrome P450, family 2, subfamily s, polypeptide 1 |
affects expression |
ISO |
Fluorouracil affects the expression of CYP2S1 mRNA |
CTD |
PMID:20421339 |
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NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
affects expression |
ISO |
Fluorouracil affects the expression of CYP3A4 mRNA |
CTD |
PMID:16584549 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp51 |
cytochrome P450, family 51 |
affects response to substance |
ISO |
CYP51A1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G |
Cyth3 |
cytohesin 3 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of CYTH3 protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr12:10,840,137...10,933,792
Ensembl chr12:10,840,157...10,933,812
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G |
Dapk1 |
death associated protein kinase 1 |
affects expression increases expression |
ISO |
Fluorouracil affects the expression of DAPK1 mRNA Fluorouracil results in increased expression of DAPK1 protein |
CTD |
PMID:20421339 PMID:30177839 |
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NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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G |
Dars1 |
aspartyl-tRNA synthetase 1 |
affects expression |
ISO |
Fluorouracil affects the expression of DARS1 mRNA |
CTD |
PMID:16584549 |
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NCBI chr13:39,857,936...39,913,055
Ensembl chr13:39,857,936...39,913,116
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G |
Dbf4 |
DBF4-CDC7 kinase regulatory subunit |
decreases expression |
ISO |
Fluorouracil results in decreased expression of DBF4 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
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G |
Dbndd2 |
dysbindin domain containing 2 |
affects response to substance |
ISO |
DBNDD2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 3:153,216,300...153,220,651
Ensembl chr 3:153,191,090...153,220,651
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G |
Dcc |
DCC netrin 1 receptor |
multiple interactions |
ISO |
DCC protein results in increased susceptibility to [Fluorouracil co-treated with Levamisole] |
CTD |
PMID:15148649 |
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NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740
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G |
Dck |
deoxycytidine kinase |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCK mRNA] |
CTD |
PMID:15016801 |
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NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247
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G |
Dclk1 |
doublecortin-like kinase 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCLK1 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956
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G |
Dct |
dopachrome tautomerase |
affects expression |
ISO |
Fluorouracil affects the expression of DCT mRNA |
CTD |
PMID:15205334 |
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NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
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G |
Dcx |
doublecortin |
decreases expression |
EXP |
Fluorouracil results in decreased expression of DCX protein |
CTD |
PMID:18702703 |
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NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476
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G |
Dcxr |
dicarbonyl and L-xylulose reductase |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCXR mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr10:106,006,404...106,008,293
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G |
Ddah2 |
DDAH family member 2, ADMA-independent |
affects response to substance |
ISO |
DDAH2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511
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G |
Ddb2 |
damage specific DNA binding protein 2 |
affects response to substance increases expression multiple interactions |
ISO |
DDB2 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of DDB2 mRNA TP53 protein promotes the reaction [Fluorouracil results in increased expression of DDB2 mRNA] |
CTD |
PMID:15331170 PMID:16584549 PMID:17982676 PMID:22525470 |
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NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
Fluorouracil results in increased expression of DDIT3 mRNA; Fluorouracil results in increased expression of DDIT3 protein |
CTD |
PMID:17355264 PMID:29879413 PMID:32535746 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
increases expression |
ISO |
Fluorouracil results in increased expression of DDIT4 mRNA |
CTD |
PMID:16510598 PMID:16557594 PMID:17039268 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Ddx39b |
DExD-box helicase 39B |
increases expression |
ISO |
Fluorouracil results in increased expression of DDX39B mRNA |
CTD |
PMID:16510598 |
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NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996
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G |
Ddx4 |
DEAD-box helicase 4 |
increases expression |
ISO |
Fluorouracil results in increased expression of DDX4 protein |
CTD |
PMID:21296659 |
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NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723
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G |
Dennd2c |
DENN domain containing 2C |
affects expression |
ISO |
Fluorouracil affects the expression of DENND2C mRNA |
CTD |
PMID:20421339 |
|
NCBI chr 2:190,622,357...190,690,489
Ensembl chr 2:190,622,940...190,690,488
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G |
Depdc7 |
DEP domain containing 7 |
affects expression |
ISO |
Fluorouracil affects the expression of DEPDC7 mRNA |
CTD |
PMID:20421339 |
|
NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124
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G |
Des |
desmin |
decreases expression |
ISO |
Fluorouracil results in decreased expression of DES protein |
CTD |
PMID:21296659 |
|
NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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G |
Dffa |
DNA fragmentation factor subunit alpha |
decreases expression |
ISO |
Fluorouracil results in decreased expression of DFFA mRNA |
CTD |
PMID:34151400 |
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NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633
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G |
Dhfr |
dihydrofolate reductase |
affects expression increases expression |
ISO |
Fluorouracil affects the expression of DHFR mRNA Fluorouracil results in increased expression of DHFR mRNA |
CTD |
PMID:15109396 PMID:16557594 PMID:21814787 |
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NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
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G |
Dhx15 |
DEAH-box helicase 15 |
increases expression |
ISO |
Fluorouracil results in increased expression of DHX15 mRNA |
CTD |
PMID:16584549 |
|
NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
increases response to substance increases expression |
ISO |
DIABLO protein results in increased susceptibility to Fluorouracil Fluorouracil results in increased expression of DIABLO mRNA |
CTD |
PMID:16557594 PMID:18031615 |
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NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
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G |
Dicer1 |
dicer 1 ribonuclease III |
decreases expression |
ISO |
Fluorouracil results in decreased expression of DICER1 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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G |
Dimt1 |
DIM1 rRNA methyltransferase and ribosome maturation factor |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of DIMT1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 2:38,343,086...38,368,242
Ensembl chr 2:38,354,854...38,368,227
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of DKK1 protein DKK1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 PMID:16217747 |
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NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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Dkk4 |
dickkopf WNT signaling pathway inhibitor 4 |
increases expression |
ISO |
Fluorouracil results in increased expression of DKK4 mRNA |
CTD |
PMID:16584549 |
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NCBI chr16:69,403,215...69,406,580
Ensembl chr16:69,402,989...69,406,580
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G |
Dlc1 |
DLC1 Rho GTPase activating protein |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLC1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
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G |
Dlg1 |
discs large MAGUK scaffold protein 1 |
multiple interactions |
ISO |
DLG1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] |
CTD |
PMID:18927307 |
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NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
multiple interactions increases expression |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLK1 mRNA] Fluorouracil results in increased expression of DLK1 mRNA |
CTD |
PMID:15016801 PMID:24737281 |
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NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
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G |
Dnah2 |
dynein, axonemal, heavy chain 2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of DNAH2 mRNA |
CTD |
PMID:24737281 |
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NCBI chr10:54,142,648...54,268,901
Ensembl chr10:54,142,737...54,267,298
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G |
Dner |
delta/notch-like EGF repeat containing |
increases expression |
ISO |
Fluorouracil results in increased expression of DNER mRNA |
CTD |
PMID:16510598 |
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NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637
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G |
Dnmt3b |
DNA methyltransferase 3 beta |
decreases expression |
ISO |
Fluorouracil results in decreased expression of DNMT3B protein |
CTD |
PMID:21296659 |
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NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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G |
Dpagt1 |
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 |
affects response to substance |
ISO |
DPAGT1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 8:44,664,055...44,671,102
Ensembl chr 8:44,664,071...44,671,087
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G |
Dpy19l1 |
dpy-19 like C-mannosyltransferase 1 |
affects response to substance |
ISO |
DPY19L1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 8:22,933,163...23,021,461
Ensembl chr 8:22,933,163...23,021,751
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G |
Dpyd |
dihydropyrimidine dehydrogenase |
increases response to substance decreases expression increases metabolic processing decreases response to substance increases activity increases expression affects activity increases degradation decreases metabolic processing affects degradation affects response to substance affects metabolic processing multiple interactions |
ISO |
DPYD gene mutant form results in increased susceptibility to Fluorouracil; DPYD gene polymorphism results in increased susceptibility to Fluorouracil; DPYD mRNA results in increased susceptibility to Fluorouracil Fluorouracil results in decreased expression of DPYD mRNA DPYD protein results in increased metabolism of Fluorouracil DPYD mRNA results in decreased susceptibility to Fluorouracil; DPYD protein results in decreased susceptibility to Fluorouracil Fluorouracil results in increased activity of DPYD protein Fluorouracil results in increased expression of DPYD mRNA; Fluorouracil results in increased expression of DPYD protein Fluorouracil metabolite affects the activity of DPYD protein DPYD protein results in increased degradation of Fluorouracil DPYD gene polymorphism results in decreased metabolism of Fluorouracil; DPYD protein mutant form results in decreased metabolism of Fluorouracil DPYD protein affects the degradation of Fluorouracil DPYD gene polymorphism affects the susceptibility to Fluorouracil; DPYD gene SNP affects the susceptibility to Fluorouracil; DPYD intron polymorphism affects the susceptibility to Fluorouracil; DPYD mRNA affects the susceptibility to Fluorouracil; DPYD promoter modified form affects the susceptibility to Fluorouracil; DPYD protein affects the susceptibility to Fluorouracil; DPYD protein mutant form affects the susceptibility to Fluorouracil DPYD affects the metabolism of Fluorouracil; DPYD protein affects the metabolism of Fluorouracil [Cisplatin co-treated with Fluorouracil] results in decreased expression of DPYD mRNA; [docetaxel co-treated with Fluorouracil] results in decreased expression of DPYD mRNA; [Leucovorin co-treated with Fluorouracil] results in decreased activity of DPYD protein; Camptothecin inhibits the reaction [Fluorouracil results in increased expression of DPYD mRNA]; Cisplatin inhibits the reaction [Fluorouracil results in increased expression of DPYD mRNA]; docetaxel inhibits the reaction [Fluorouracil results in increased activity of DPYD protein]; DPYD protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin]; DPYD results in increased susceptibility to [Fluorouracil co-treated with gimeracil]; Fluorouracil inhibits the reaction [docetaxel results in increased expression of DPYD protein]; gimeracil affects the reaction [DPYD protein results in increased susceptibility to Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in decreased susceptibility to Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in increased degradation of Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in increased metabolism of Fluorouracil] |
CTD |
PMID:3335642 PMID:7503095 PMID:8680084 PMID:9470816 PMID:9816193 PMID:10099659 PMID:11148247 PMID:12044515 PMID:12562666 PMID:12635664 PMID:14689231 PMID:15017333 PMID:15109396 PMID:15239142 PMID:15246190 PMID:15591715 PMID:15655543 PMID:15737843 PMID:15858133 PMID:15865071 PMID:15890242 PMID:15930747 PMID:15949589 PMID:15993511 PMID:16033824 PMID:16115930 PMID:16282729 PMID:16361556 PMID:16525674 PMID:16557585 PMID:16568373 PMID:16646564 PMID:16761622 PMID:17046731 PMID:17064846 PMID:17121937 PMID:17330233 PMID:17377791 PMID:18075467 PMID:18197934 PMID:18225548 PMID:18299612 PMID:18383874 PMID:18443386 PMID:18600527 PMID:18619742 PMID:18846242 PMID:18986760 PMID:19020767 PMID:19093184 PMID:19104657 PMID:19105824 PMID:19219653 More...
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NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
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G |
Dpysl3 |
dihydropyrimidinase-like 3 |
affects expression |
ISO |
Fluorouracil affects the expression of DPYSL3 mRNA |
CTD |
PMID:15205334 |
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NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
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G |
Dram1 |
DNA-damage regulated autophagy modulator 1 |
multiple interactions increases expression |
ISO |
TP53 protein promotes the reaction [Fluorouracil results in increased expression of DRAM1 mRNA] Fluorouracil promotes the reaction [Luteolin results in increased expression of DRAM1 protein]; Luteolin promotes the reaction [Fluorouracil results in increased expression of DRAM1 protein] |
CTD |
PMID:17982676 PMID:31288002 |
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NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765
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G |
Drd5 |
dopamine receptor D5 |
multiple interactions |
ISO |
DRD5 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] |
CTD |
PMID:17327601 |
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NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774
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G |
Dst |
dystonin |
affects response to substance |
ISO |
DST protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
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G |
Dtwd1 |
DTW domain containing 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of DTWD1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 3:113,392,402...113,409,322
Ensembl chr 3:113,392,457...113,408,105
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G |
Dtymk |
deoxythymidylate kinase |
affects response to substance multiple interactions increases expression |
ISO |
DTYMK affects the susceptibility to Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of DTYMK mRNA] Fluorouracil results in increased expression of DTYMK mRNA |
CTD |
PMID:15016801 PMID:15067352 PMID:15109396 |
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NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
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G |
Dusp14 |
dual specificity phosphatase 14 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP14 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP5 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp6 |
dual specificity phosphatase 6 |
increases expression |
ISO |
Fluorouracil results in increased expression of DUSP6 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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G |
Dut |
deoxyuridine triphosphatase |
decreases response to substance decreases expression |
ISO |
DUT protein results in decreased susceptibility to Fluorouracil Fluorouracil results in decreased expression of DUT mRNA |
CTD |
PMID:16557594 PMID:19015155 |
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NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
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G |
E2f1 |
E2F transcription factor 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of E2F1 mRNA |
CTD |
PMID:34151400 |
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NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
E2f2 |
E2F transcription factor 2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of E2F2; Fluorouracil results in decreased expression of E2F2 mRNA |
CTD |
PMID:11300326 PMID:34151400 |
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NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
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G |
E2f3 |
E2F transcription factor 3 |
multiple interactions |
ISO |
E2F3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] |
CTD |
PMID:16896004 |
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NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
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G |
E2f4 |
E2F transcription factor 4 |
multiple interactions decreases expression |
ISO |
CDKN1A protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]; TP53 protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]] Fluorouracil results in decreased expression of E2F4 mRNA |
CTD |
PMID:27129209 PMID:34151400 |
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NCBI chr19:33,174,396...33,181,806
Ensembl chr19:33,174,410...33,181,806
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G |
E2f8 |
E2F transcription factor 8 |
affects expression |
ISO |
Fluorouracil affects the expression of E2F8 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
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G |
Ebp |
EBP, cholestenol delta-isomerase |
affects response to substance |
ISO |
EBP protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 PMID:16217747 |
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NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
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G |
Echdc3 |
enoyl CoA hydratase domain containing 3 |
affects response to substance |
ISO |
ECHDC3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of ECHS1 mRNA |
CTD |
PMID:15152939 |
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NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
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G |
Ect2 |
epithelial cell transforming 2 |
multiple interactions decreases expression |
ISO |
TP53 protein promotes the reaction [Fluorouracil results in decreased expression of ECT2 mRNA] |
CTD |
PMID:17982676 |
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NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
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G |
Edil3 |
EGF like repeats and discoidin domains 3 |
affects response to substance |
ISO |
EDIL3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008
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G |
Edn1 |
endothelin 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of EDN1 mRNA; Fluorouracil results in increased expression of EDN1 protein |
CTD |
PMID:1606078 PMID:19098008 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Ednra |
endothelin receptor type A |
affects response to substance |
ISO |
EDNRA protein affects the susceptibility to Fluorouracil |
CTD |
PMID:17032313 |
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NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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G |
Ednrb |
endothelin receptor type B |
decreases expression |
ISO |
Fluorouracil results in decreased expression of EDNRB mRNA |
CTD |
PMID:24737281 |
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NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
affects expression multiple interactions increases expression |
ISO |
Fluorouracil affects the expression of EEF1A1 protein TP53 protein inhibits the reaction [Fluorouracil results in increased expression of EEF1A1 mRNA] |
CTD |
PMID:17982676 PMID:21296659 |
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NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
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G |
Eeig1 |
estrogen-induced osteoclastogenesis regulator 1 |
affects expression |
ISO |
Fluorouracil affects the expression of EEIG1 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 3:15,822,441...15,854,651
Ensembl chr 3:15,823,144...15,854,643
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G |
Efemp1 |
EGF containing fibulin extracellular matrix protein 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of EFEMP1 mRNA |
CTD |
PMID:24737281 |
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NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
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G |
Efhd1 |
EF-hand domain family, member D1 |
affects response to substance |
ISO |
EFHD1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917
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G |
Efhd2 |
EF-hand domain family, member D2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of EFHD2 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980
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G |
Efnb2 |
ephrin B2 |
affects response to substance decreases expression |
ISO |
EFNB2 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of EFNB2 protein |
CTD |
PMID:15352031 PMID:16217747 |
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NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
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G |
Egf |
epidermal growth factor |
multiple interactions |
ISO |
[Fluorouracil co-treated with EGF protein] results in increased expression of MT2A mRNA; EGF protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; EGF protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]] |
CTD |
PMID:28507149 |
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NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
decreases response to substance decreases expression increases phosphorylation affects response to substance multiple interactions |
ISO |
EGFR gene polymorphism results in decreased susceptibility to Fluorouracil Fluorouracil results in decreased expression of EGFR protein Fluorouracil results in increased phosphorylation of EGFR protein EGFR protein affects the susceptibility to Fluorouracil [Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA; EGFR gene polymorphism affects the susceptibility to [oxaliplatin co-treated with Fluorouracil]; EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil]; EGFR results in increased susceptibility to [Cisplatin co-treated with docetaxel co-treated with Fluorouracil]; Fluorouracil promotes the reaction [Curcumin results in decreased expression of EGFR protein]; Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein]; Fluorouracil results in decreased phosphorylation of and results in decreased activity of EGFR protein; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EGFR protein] |
CTD |
PMID:15737843 PMID:15981280 PMID:16098254 PMID:16836928 PMID:17169374 PMID:17918158 PMID:17982676 PMID:18794807 PMID:19217205 PMID:21947696 More...
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
multiple interactions affects expression affects localization increases expression decreases expression |
ISO |
EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 mRNA]; EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 protein]; Fluorouracil promotes the reaction [EGR1 protein binds to THBS1 promoter]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of EGR1 mRNA]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of EGR1 protein] Fluorouracil affects the expression of EGR1 mRNA Fluorouracil affects the localization of EGR1 protein Fluorouracil results in decreased expression of EGR1 mRNA |
CTD |
PMID:15205334 PMID:16557594 PMID:17039268 PMID:18757417 |
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Ehd2 |
EH-domain containing 2 |
affects response to substance |
ISO |
EHD2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783
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G |
Ehf |
ets homologous factor |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of EHF mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
increases phosphorylation increases expression |
ISO |
Fluorouracil results in increased phosphorylation of EIF2AK3 protein Fluorouracil results in increased expression of EIF2AK3 mRNA |
CTD |
PMID:29879413 PMID:32535746 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2b2 |
eukaryotic translation initiation factor 2B subunit beta |
decreases expression |
ISO |
Fluorouracil results in decreased expression of EIF2B2 protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation |
ISO |
Fluorouracil results in increased phosphorylation of EIF2S1 protein |
CTD |
PMID:29879413 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif3h |
eukaryotic translation initiation factor 3, subunit H |
increases expression |
ISO |
Fluorouracil results in increased expression of EIF3H protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451
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G |
Eif4e |
eukaryotic translation initiation factor 4E |
increases expression multiple interactions |
ISO |
Fluorouracil results in increased expression of EIF4E mRNA Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIF4E mRNA] |
CTD |
PMID:15016801 PMID:15611226 PMID:16584549 |
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NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
ISO |
Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] |
CTD |
PMID:15611226 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Eif4h |
eukaryotic translation initiation factor 4H |
increases expression |
ISO |
Fluorouracil results in increased expression of EIF4H protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
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G |
Eif5 |
eukaryotic translation initiation factor 5 |
increases expression |
ISO |
Fluorouracil results in increased expression of EIF5 mRNA |
CTD |
PMID:17039268 |
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NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
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G |
Eipr1 |
EARP complex and GARP complex interacting protein 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIPR1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 6:45,388,451...45,502,089
Ensembl chr 6:45,388,376...45,502,083
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G |
Elmo2 |
engulfment and cell motility 2 |
increases expression |
ISO |
Fluorouracil results in increased expression of ELMO2 protein |
CTD |
PMID:16803524 |
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NCBI chr 3:154,023,661...154,061,259
Ensembl chr 3:154,023,661...154,061,185
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G |
Eln |
elastin |
affects expression |
ISO |
Fluorouracil affects the expression of ELN mRNA |
CTD |
PMID:15205334 |
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NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
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G |
Eloa |
elongin A |
affects expression |
ISO |
Fluorouracil affects the expression of ELOA mRNA |
CTD |
PMID:15205334 |
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NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:148,231,596...148,246,765
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G |
Elovl5 |
ELOVL fatty acid elongase 5 |
affects response to substance |
ISO |
ELOVL5 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
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G |
Emc1 |
ER membrane protein complex subunit 1 |
affects expression |
ISO |
Fluorouracil affects the expression of EMC1 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:151,608,568...151,633,888
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G |
Eml2 |
EMAP like 2 |
multiple interactions |
ISO |
EML2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] |
CTD |
PMID:17327601 |
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NCBI chr 1:78,827,595...78,859,342
Ensembl chr 1:78,828,080...78,859,341
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G |
Emp3 |
epithelial membrane protein 3 |
increases expression |
ISO |
Fluorouracil results in increased expression of EMP3 mRNA |
CTD |
PMID:19272435 |
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NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
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G |
Enah |
ENAH, actin regulator |
affects response to substance |
ISO |
ENAH protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr13:93,617,747...93,738,119
Ensembl chr13:93,626,944...93,740,955
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G |
Endog |
endonuclease G |
increases expression multiple interactions |
ISO |
Fluorouracil results in increased expression of ENDOG protein casticin inhibits the reaction [Fluorouracil results in increased expression of ENDOG protein] |
CTD |
PMID:32270916 |
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NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
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G |
Enosf1 |
enolase superfamily member 1 |
affects response to substance decreases response to substance |
ISO |
ENOSF1 protein affects the susceptibility to Fluorouracil ENOSF1 protein results in decreased susceptibility to Fluorouracil |
CTD |
PMID:15548681 PMID:18357371 |
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NCBI chr 9:113,275,267...113,314,842
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G |
Entpd1 |
ectonucleoside triphosphate diphosphohydrolase 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ENTPD1 mRNA |
CTD |
PMID:19219653 |
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NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
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G |
Entrep3 |
endosomal transmembrane epsin interactor 3 |
affects response to substance |
ISO |
ENTREP3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 2:174,588,984...174,595,281
Ensembl chr 2:174,589,337...174,595,281
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G |
Eomes |
eomesodermin |
decreases expression |
ISO |
Fluorouracil results in decreased expression of EOMES protein |
CTD |
PMID:21296659 |
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NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
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G |
Ep300 |
E1A binding protein p300 |
multiple interactions |
ISO |
Fluorouracil promotes the reaction [EP300 protein binds to UBE2C promoter] |
CTD |
PMID:27129209 |
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NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Ep400 |
E1A binding protein p400 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of EP400 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861
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G |
Epas1 |
endothelial PAS domain protein 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of EPAS1 mRNA |
CTD |
PMID:16557594 |
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NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Epb41l3 |
erythrocyte membrane protein band 4.1-like 3 |
affects expression |
ISO |
Fluorouracil affects the expression of EPB41L3 mRNA |
CTD |
PMID:20421339 |
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NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607
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G |
Epha2 |
Eph receptor A2 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in increased expression of EPHA2 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
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G |
Ephx1 |
epoxide hydrolase 1 |
affects response to substance increases expression |
ISO |
EPHX1 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of EPHX1 mRNA |
CTD |
PMID:15205334 PMID:16217747 |
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NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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G |
Epo |
erythropoietin |
increases response to substance increases expression |
ISO EXP |
EPO protein results in increased susceptibility to Fluorouracil Fluorouracil results in increased expression of EPO protein |
CTD |
PMID:2206997 PMID:16103069 PMID:20020992 |
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NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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G |
Epor |
erythropoietin receptor |
affects response to substance |
ISO |
EPOR gene mutant form affects the susceptibility to Fluorouracil |
CTD |
PMID:16511603 |
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NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
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G |
Eppk1 |
epiplakin 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of EPPK1 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 7:107,816,919...107,842,946
Ensembl chr 7:107,817,693...107,831,159
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G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of EPRS1 mRNA |
CTD |
PMID:16709241 |
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NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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G |
Epyc |
epiphycan |
affects expression |
ISO |
Fluorouracil affects the expression of EPYC mRNA |
CTD |
PMID:15205334 |
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NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135
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G |
Eras |
ES cell expressed Ras |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ERAS protein |
CTD |
PMID:21296659 |
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NCBI chr X:14,573,987...14,578,455
Ensembl chr X:14,573,987...14,578,374
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions affects response to substance affects expression decreases response to substance |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; [Apigenin co-treated with Fluorouracil] results in decreased expression of ERBB2 protein; [Cisplatin co-treated with Fluorouracil] results in decreased expression of ERBB2 mRNA; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; Curcumin promotes the reaction [Fluorouracil results in decreased phosphorylation of and results in decreased expression of and results in decreased activity of ERBB2 protein]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with pirarubicin co-treated with Fluorouracil]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein ERBB2 mRNA alternative form affects the susceptibility to Fluorouracil Fluorouracil affects the expression of ERBB2 mRNA ERBB2 mRNA results in decreased susceptibility to Fluorouracil; ERBB2 results in decreased susceptibility to Fluorouracil |
CTD |
PMID:9816327 PMID:15205334 PMID:15737843 PMID:15940066 PMID:16446318 PMID:16682728 PMID:17918158 PMID:18337622 PMID:19885610 PMID:21712253 PMID:36639866 More...
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NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
multiple interactions |
ISO |
Fluorouracil promotes the reaction [Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein |
CTD |
PMID:17918158 |
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NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
multiple interactions |
ISO |
ERBB4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] |
CTD |
PMID:16896004 |
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NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
multiple interactions decreases expression |
ISO |
[Cisplatin co-treated with Fluorouracil] results in decreased expression of ERCC1 mRNA; ERCC1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with Oxaliplatin]; ERCC1 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Oxaliplatin]; ERCC1 gene SNP results in increased susceptibility to [Cisplatin co-treated with Fluorouracil]; ERCC1 mRNA affects the susceptibility to [Cisplatin co-treated with Fluorouracil] Fluorouracil results in decreased expression of ERCC1 mRNA |
CTD |
PMID:15173087 PMID:15213713 PMID:15737843 PMID:17016597 PMID:17401013 PMID:18448328 PMID:21286668 More...
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NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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G |
Ercc2 |
ERCC excision repair 2, TFIIH core complex helicase subunit |
multiple interactions |
ISO |
ERCC2 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]; ERCC2 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin] |
CTD |
PMID:15213713 PMID:17401013 |
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NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
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G |
Ereg |
epiregulin |
decreases expression |
ISO |
Fluorouracil results in decreased expression of EREG mRNA |
CTD |
PMID:16510598 |
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NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of ERN1 mRNA |
CTD |
PMID:32535746 |
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Erp29 |
endoplasmic reticulum protein 29 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of ERP29 protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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G |
Espl1 |
extra spindle pole bodies like 1, separase |
affects response to substance |
ISO |
ESPL1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
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G |
Etf1 |
eukaryotic translation termination factor 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETF1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810
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G |
Etfb |
electron transfer flavoprotein subunit beta |
affects response to substance |
ISO |
ETFB protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
multiple interactions increases expression |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETS1 mRNA] Fluorouracil results in increased expression of ETS1 protein |
CTD |
PMID:15016801 PMID:30177839 |
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NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G |
Etv2 |
ETS variant transcription factor 2 |
multiple interactions |
ISO |
Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
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NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431
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G |
Exo1 |
exonuclease 1 |
affects response to substance |
ISO |
HEXO1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16477629 |
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NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
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G |
Exosc10 |
exosome component 10 |
affects response to substance increases metabolic processing |
ISO |
EXOSC10 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased metabolism of EXOSC10 protein |
CTD |
PMID:18567802 |
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NCBI chr 5:158,995,313...159,018,940
Ensembl chr 5:158,995,313...159,018,940
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G |
F12 |
coagulation factor XII |
affects response to substance decreases expression |
ISO |
F12 protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased expression of F12 protein |
CTD |
PMID:15352031 |
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NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
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G |
F2 |
coagulation factor II, thrombin |
decreases expression |
ISO |
Fluorouracil results in decreased expression of F2 mRNA |
CTD |
PMID:16709241 |
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NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
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G |
F3 |
coagulation factor III, tissue factor |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of F3 mRNA F3 affects the susceptibility to Fluorouracil |
CTD |
PMID:15067352 PMID:16510598 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
F8 |
coagulation factor VIII |
multiple interactions |
ISO |
F8 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] |
CTD |
PMID:17327601 |
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NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
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G |
Fabp7 |
fatty acid binding protein 7 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FABP7 mRNA |
CTD |
PMID:24737281 |
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NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
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G |
Fadd |
Fas associated via death domain |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FADD mRNA |
CTD |
PMID:34151400 |
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NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
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G |
Fads1 |
fatty acid desaturase 1 |
affects response to substance |
ISO |
FADS1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
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G |
Fah |
fumarylacetoacetate hydrolase |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAH mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
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G |
Fam107b |
family with sequence similarity 107, member B |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAM107B mRNA] |
CTD |
PMID:15016801 |
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NCBI chr17:74,478,608...74,685,027
Ensembl chr17:74,478,608...74,684,989
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G |
Fam114a1 |
family with sequence similarity 114, member A1 |
affects expression |
ISO |
Fluorouracil affects the expression of FAM114A1 mRNA |
CTD |
PMID:16584549 |
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NCBI chr14:43,275,693...43,346,154
Ensembl chr14:43,275,701...43,346,174
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G |
Fam171a1 |
family with sequence similarity 171, member A1 |
affects response to substance |
ISO |
FAM171A1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr17:75,024,582...75,148,348
Ensembl chr17:75,024,575...75,150,255
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G |
Fam20c |
FAM20C, golgi associated secretory pathway kinase |
affects expression |
ISO |
Fluorouracil affects the expression of FAM20C mRNA |
CTD |
PMID:16584549 |
|
NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543
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G |
Fam234b |
family with sequence similarity 234, member B |
multiple interactions |
ISO |
FAM234B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] |
CTD |
PMID:16896004 |
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NCBI chr 4:168,048,313...168,124,017
Ensembl chr 4:168,048,396...168,097,338
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G |
Fam76b |
family with sequence similarity 76, member B |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FAM76B mRNA |
CTD |
PMID:16510598 |
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NCBI chr 8:10,689,396...10,711,847
Ensembl chr 8:10,688,963...10,711,861
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G |
Fancc |
FA complementation group C |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FANCC mRNA |
CTD |
PMID:16557594 |
|
NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376
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G |
Fancg |
FA complementation group G |
increases expression affects response to substance |
ISO |
Fluorouracil results in increased expression of FANCG mRNA FANCG affects the susceptibility to Fluorouracil; FANCG protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15067352 PMID:15109396 PMID:15548681 |
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NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029
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G |
Fanci |
FA complementation group I |
affects response to substance |
ISO |
FANCI protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
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G |
Fars2 |
phenylalanyl-tRNA synthetase 2, mitochondrial |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FARS2 mRNA |
CTD |
PMID:16101138 |
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NCBI chr17:28,319,215...28,746,217
Ensembl chr17:28,319,280...28,746,337
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
ISO |
[Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of FAS mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of FAS protein; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP8 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP9 protein]; N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]] Fluorouracil results in increased expression of FAS; Fluorouracil results in increased expression of FAS mRNA; Fluorouracil results in increased expression of FAS protein |
CTD |
PMID:11300326 PMID:14665630 PMID:15016801 PMID:15034078 PMID:15152939 PMID:15161716 PMID:15546879 PMID:15585135 PMID:16557594 PMID:16596200 PMID:16709241 PMID:16957513 PMID:17039268 PMID:17045692 PMID:17056233 PMID:17982676 PMID:18074150 PMID:19015929 PMID:22525470 PMID:33770205 PMID:34151400 More...
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
increases response to substance increases expression |
ISO |
FASL results in increased susceptibility to Fluorouracil Fluorouracil results in increased expression of FASL |
CTD |
PMID:11196169 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fastk |
Fas-activated serine/threonine kinase |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FASTK mRNA |
CTD |
PMID:34151400 |
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NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430
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G |
Fbln1 |
fibulin 1 |
affects expression increases expression |
ISO |
Fluorouracil affects the expression of FBLN1 mRNA Fluorouracil results in increased expression of FBLN1 mRNA |
CTD |
PMID:15205334 PMID:17039268 |
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NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
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G |
Fbxo5 |
F-box protein 5 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FBXO5 mRNA |
CTD |
PMID:16557594 PMID:19272435 |
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NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
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G |
Fdxr |
ferredoxin reductase |
multiple interactions increases expression |
ISO |
TP53 protein affects the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR protein] Fluorouracil results in increased expression of FDXR mRNA; Fluorouracil results in increased expression of FDXR mRNA alternative form; Fluorouracil results in increased expression of FDXR protein |
CTD |
PMID:14665630 PMID:15016801 PMID:15205334 PMID:16557594 PMID:17982676 PMID:22966307 More...
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NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
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G |
Fen1 |
flap structure-specific endonuclease 1 |
affects response to substance increases expression |
ISO |
FEN1 affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of FEN1 mRNA |
CTD |
PMID:15067352 PMID:15109396 |
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NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
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G |
Fermt2 |
FERM domain containing kindlin 2 |
affects response to substance |
ISO |
FERMT2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
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G |
Fgd6 |
FYVE, RhoGEF and PH domain containing 6 |
affects response to substance |
ISO |
FGD6 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456
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G |
Fgf2 |
fibroblast growth factor 2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FGF2 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf4 |
fibroblast growth factor 4 |
affects expression |
ISO |
Fluorouracil affects the expression of FGF4 protein |
CTD |
PMID:21296659 |
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NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
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G |
Fgf5 |
fibroblast growth factor 5 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FGF5 protein |
CTD |
PMID:21296659 |
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NCBI chr14:11,323,827...11,346,164
Ensembl chr14:11,325,334...11,345,997
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G |
Fgf7 |
fibroblast growth factor 7 |
decreases response to substance multiple interactions |
ISO |
FGF7 protein results in decreased susceptibility to Fluorouracil; FGF7 results in decreased susceptibility to Fluorouracil FGFR2 inhibits the reaction [FGF7 results in decreased susceptibility to Fluorouracil]; FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil] |
CTD |
PMID:18575591 |
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NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
multiple interactions |
ISO |
FGFR2 inhibits the reaction [FGF7 results in decreased susceptibility to Fluorouracil]; FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil] |
CTD |
PMID:18575591 |
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NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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G |
Fgg |
fibrinogen gamma chain |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of FGG mRNA FGG protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 PMID:17039268 |
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NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
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G |
Fhl2 |
four and a half LIM domains 2 |
affects response to substance |
ISO |
FHL2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192
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G |
Fhl3 |
four and a half LIM domains 3 |
increases expression |
ISO |
Fluorouracil results in increased expression of FHL3 mRNA |
CTD |
PMID:17039268 |
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NCBI chr 5:136,953,947...136,961,317
Ensembl chr 5:136,950,411...136,961,317
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G |
Fibcd1 |
fibrinogen C domain containing 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FIBCD1 mRNA |
CTD |
PMID:34151400 |
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NCBI chr 3:15,092,682...15,126,371
Ensembl chr 3:15,092,681...15,126,399
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G |
Filip1l |
filamin A interacting protein 1-like |
affects response to substance increases expression |
ISO |
FILIP1L protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of FILIP1L protein |
CTD |
PMID:15352031 |
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NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
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G |
Fkbp11 |
FKBP prolyl isomerase 11 |
affects response to substance |
ISO |
FKBP11 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
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G |
Fkbp1b |
FKBP prolyl isomerase 1B |
affects response to substance |
ISO |
FKBP1B protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of FKBP5 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Fkbpl |
FKBP prolyl isomerase like |
increases expression |
ISO |
Fluorouracil results in increased expression of FKBPL mRNA |
CTD |
PMID:14503796 |
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NCBI chr20:4,099,845...4,101,315
Ensembl chr20:4,099,806...4,101,368
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G |
Flrt2 |
fibronectin leucine rich transmembrane protein 2 |
affects response to substance |
ISO |
FLRT2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of FLT1 protein IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of FLT1 protein] |
CTD |
PMID:18157009 |
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NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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G |
Fmod |
fibromodulin |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in increased expression of FMOD mRNA] |
CTD |
PMID:15016801 |
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NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133
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G |
Fn1 |
fibronectin 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FN1 protein |
CTD |
PMID:21296659 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fnbp1 |
formin binding protein 1 |
affects response to substance |
ISO |
FNBP1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881
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G |
Fndc3b |
fibronectin type III domain containing 3B |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of FNDC3B mRNA FNDC3B protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 PMID:16510598 |
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NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
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G |
Folr1 |
folate receptor alpha |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FOLR1 mRNA |
CTD |
PMID:16510598 |
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NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression affects expression |
ISO |
Fluorouracil results in increased expression of FOS mRNA Fluorouracil affects the expression of FOS mRNA |
CTD |
PMID:15205334 PMID:17039268 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
affects expression |
ISO |
Fluorouracil affects the expression of FOSL1 mRNA |
CTD |
PMID:34151400 |
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NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
Foxa2 |
forkhead box A2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FOXA2 protein |
CTD |
PMID:21296659 |
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NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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G |
Foxc1 |
forkhead box C1 |
affects expression |
ISO |
Fluorouracil affects the expression of FOXC1 mRNA |
CTD |
PMID:16584549 |
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NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
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G |
Foxd3 |
forkhead box D3 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FOXD3 protein |
CTD |
PMID:21296659 |
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NCBI chr 5:114,335,084...114,337,450
Ensembl chr 5:114,335,408...114,336,817
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G |
Foxg1 |
forkhead box G1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FOXG1 mRNA |
CTD |
PMID:30518710 |
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NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607
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G |
Foxl2 |
forkhead box L2 |
increases expression |
ISO |
Fluorouracil results in increased expression of FOXL2 mRNA |
CTD |
PMID:34151400 |
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NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427
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G |
Foxm1 |
forkhead box M1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of FOXM1 mRNA |
CTD |
PMID:34151400 |
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NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
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G |
Foxn3 |
forkhead box N3 |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of FOXN3 protein FOXN3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 |
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NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401
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G |
Foxo3 |
forkhead box O3 |
affects response to substance |
ISO |
FOXO3 affects the susceptibility to Fluorouracil |
CTD |
PMID:15067352 |
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NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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G |
Fpgs |
folylpolyglutamate synthase |
increases response to substance |
ISO |
FPGS protein results in increased susceptibility to Fluorouracil |
CTD |
PMID:15542523 |
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NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563
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G |
Fut1 |
fucosyltransferase 1 |
affects response to substance |
ISO |
FUT1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15649251 |
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NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
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G |
Fxyd3 |
FXYD domain-containing ion transport regulator 3 |
increases expression |
ISO |
Fluorouracil results in increased expression of FXYD3 mRNA |
CTD |
PMID:15152939 |
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NCBI chr 1:86,305,531...86,312,455
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
affects response to substance |
ISO |
FYN protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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G |
Fzd2 |
frizzled class receptor 2 |
affects response to substance |
ISO |
FZD2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
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G |
G0s2 |
G0/G1switch 2 |
increases expression affects response to substance |
ISO |
Fluorouracil results in increased expression of G0S2 protein G0S2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 |
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NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
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G |
Gabrb3 |
gamma-aminobutyric acid type A receptor subunit beta 3 |
increases expression |
ISO |
Fluorouracil results in increased expression of GABRB3 protein |
CTD |
PMID:21296659 |
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NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression decreases expression affects response to substance increases response to substance multiple interactions |
ISO |
Fluorouracil results in increased expression of GADD45A mRNA; Fluorouracil results in increased expression of GADD45A protein Fluorouracil results in decreased expression of GADD45A mRNA GADD45A protein affects the susceptibility to Fluorouracil GADD45A protein results in increased susceptibility to Fluorouracil GADD45A affects the susceptibility to Fluorouracil TP53 protein affects the reaction [Fluorouracil results in increased expression of GADD45A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of GADD45A mRNA] |
CTD |
PMID:15016801 PMID:15067352 PMID:15205334 PMID:16709241 PMID:16732331 PMID:17982676 PMID:19003803 PMID:19098008 PMID:19272435 PMID:22525470 PMID:30177839 More...
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NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
decreases response to substance affects response to substance multiple interactions |
ISO |
GADD45B protein results in decreased susceptibility to Fluorouracil GADD45B protein affects the susceptibility to Fluorouracil IFNG protein inhibits the reaction [GADD45B protein results in decreased susceptibility to Fluorouracil] |
CTD |
PMID:16732331 PMID:17711513 |
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NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
ISO |
Fluorouracil results in increased expression of GADD45G mRNA |
CTD |
PMID:19272435 |
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NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
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G |
Gal |
galanin and GMAP prepropeptide |
decreases expression |
ISO |
Fluorouracil results in decreased expression of GAL protein |
CTD |
PMID:21296659 |
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NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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G |
Galnt3 |
polypeptide N-acetylgalactosaminyltransferase 3 |
affects response to substance |
ISO |
GALNT3 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268
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G |
Gamt |
guanidinoacetate N-methyltransferase |
increases expression affects response to substance multiple interactions |
ISO |
Fluorouracil results in increased expression of GAMT protein GAMT protein affects the susceptibility to Fluorouracil GAMT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GAMT mRNA] |
CTD |
PMID:15016801 PMID:15352031 PMID:16896004 |
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NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
affects splicing decreases expression |
ISO |
Fluorouracil affects the splicing of GAPDH mRNA Fluorouracil results in decreased expression of GAPDH protein |
CTD |
PMID:17169984 PMID:21296659 |
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NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gart |
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
increases expression |
ISO |
Fluorouracil results in increased expression of GART mRNA |
CTD |
PMID:19219653 |
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NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125
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G |
Gast |
gastrin |
decreases response to substance |
ISO |
GAST protein modified form results in decreased susceptibility to Fluorouracil |
CTD |
PMID:16618411 |
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NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
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G |
Gata2 |
GATA binding protein 2 |
multiple interactions |
ISO |
Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
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NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
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G |
Gata4 |
GATA binding protein 4 |
affects expression |
ISO |
Fluorouracil affects the expression of GATA4 protein |
CTD |
PMID:21296659 |
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NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
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G |
Gata6 |
GATA binding protein 6 |
affects expression |
ISO |
Fluorouracil affects the expression of GATA6 protein |
CTD |
PMID:21296659 |
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NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
affects response to substance |
ISO |
GCLM protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gcsh |
glycine cleavage system protein H |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of GCSH mRNA] |
CTD |
PMID:15016801 |
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NCBI chr19:45,036,013...45,046,770
Ensembl chr19:45,036,011...45,046,792
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G |
Gdf1 |
growth differentiation factor 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of GDF1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression multiple interactions |
ISO |
Fluorouracil results in increased expression of GDF15 mRNA; Fluorouracil results in increased expression of GDF15 protein TP53 protein affects the reaction [Fluorouracil results in increased expression of GDF15 mRNA] |
CTD |
PMID:14665630 PMID:15016801 PMID:15205334 PMID:24737281 |
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NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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G |
Gdf3 |
growth differentiation factor 3 |
affects expression |
ISO |
Fluorouracil affects the expression of GDF3 protein |
CTD |
PMID:21296659 |
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NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937
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G |
Gem |
GTP binding protein overexpressed in skeletal muscle |
affects expression |
ISO |
Fluorouracil affects the expression of GEM mRNA |
CTD |
PMID:15205334 |
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NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
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G |
Gfap |
glial fibrillary acidic protein |
increases expression |
ISO |
Fluorouracil results in increased expression of GFAP protein |
CTD |
PMID:21296659 |
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NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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G |
Gfra1 |
GDNF family receptor alpha 1 |
multiple interactions |
ISO |
GFRA1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] |
CTD |
PMID:16896004 |
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NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473
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G |
Gins1 |
GINS complex subunit 1 |
increases response to substance |
ISO |
GINS1 gene mutant form results in increased susceptibility to Fluorouracil |
CTD |
PMID:18984863 |
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NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936
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G |
Gins2 |
GINS complex subunit 2 |
affects expression |
ISO |
Fluorouracil affects the expression of GINS2 mRNA |
CTD |
PMID:16584549 |
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NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
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G |
Gja1 |
gap junction protein, alpha 1 |
affects response to substance |
ISO |
GJA1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 PMID:16531325 |
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NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Gjc1 |
gap junction protein, gamma 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in increased expression of GJC1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr10:87,758,192...87,785,443
Ensembl chr10:87,760,528...87,785,867
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G |
Gla |
galactosidase, alpha |
affects response to substance |
ISO |
GLA protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
|
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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G |
Gli1 |
GLI family zinc finger 1 |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of GLI1 mRNA GLI1 protein inhibits the reaction [Fluorouracil affects the localization of PTCH1 protein] |
CTD |
PMID:18776995 |
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NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
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G |
Glipr1 |
GLI pathogenesis-related 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of GLIPR1 mRNA |
CTD |
PMID:24737281 |
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NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429
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G |
Gnb2 |
G protein subunit beta 2 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of GNB2 mRNA |
CTD |
PMID:16709241 |
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NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
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G |
Gne |
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of GNE protein GNE protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 |
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NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499
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G |
Gp1bb |
glycoprotein Ib platelet subunit beta |
affects expression |
ISO |
Fluorouracil affects the expression of GP1BB mRNA |
CTD |
PMID:16584549 |
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NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392
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G |
Gpr132 |
G protein-coupled receptor 132 |
increases expression |
ISO |
Fluorouracil results in increased expression of GPR132 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 6:131,924,061...131,943,327
Ensembl chr 6:131,924,160...131,942,168
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G |
Gpr137c |
G protein-coupled receptor 137C |
affects expression |
ISO |
Fluorouracil affects the expression of GPR137C mRNA |
CTD |
PMID:16584549 |
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NCBI chr15:18,425,939...18,492,588
Ensembl chr15:18,426,223...18,490,807
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G |
Gpr35 |
G protein-coupled receptor 35 |
affects response to substance increases expression |
ISO |
GPR35 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of GPR35 mRNA |
CTD |
PMID:15331170 |
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NCBI chr 9:93,527,165...93,539,573
Ensembl chr 9:93,527,127...93,539,299
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G |
Gpr87 |
G protein-coupled receptor 87 |
increases expression |
ISO |
Fluorouracil results in increased expression of GPR87 mRNA |
CTD |
PMID:24737281 |
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NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions increases activity |
ISO EXP |
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein] Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of GPT protein] Fluorouracil results in increased activity of GPT protein |
CTD |
PMID:27836789 PMID:29678497 PMID:31129132 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx1 |
glutathione peroxidase 1 |
increases expression decreases activity multiple interactions |
ISO EXP |
Fluorouracil results in increased expression of GPX1 mRNA Fluorouracil results in decreased activity of GPX1 protein TP53 protein promotes the reaction [Fluorouracil results in increased expression of GPX1 mRNA] |
CTD |
PMID:17982676 PMID:29117755 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of GPX2 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression multiple interactions |
ISO EXP |
Fluorouracil results in decreased expression of GPX4 protein ferrostatin-1 inhibits the reaction [Fluorouracil results in decreased expression of GPX4 protein] |
CTD |
PMID:35101590 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gramd4 |
GRAM domain containing 4 |
increases expression multiple interactions |
ISO |
Fluorouracil results in increased expression of GRAMD4 mRNA TP73 protein promotes the reaction [Fluorouracil results in increased expression of GRAMD4 mRNA] |
CTD |
PMID:21127500 |
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NCBI chr 7:117,150,398...117,224,056
Ensembl chr 7:117,150,374...117,224,053
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G |
Grb7 |
growth factor receptor bound protein 7 |
increases expression |
ISO |
Fluorouracil results in increased expression of GRB7 protein |
CTD |
PMID:21296659 |
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NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052
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G |
Grhl3 |
grainyhead-like transcription factor 3 |
affects expression |
ISO |
Fluorouracil affects the expression of GRHL3 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 5:147,774,161...147,806,291
Ensembl chr 5:147,774,160...147,806,160
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G |
Grina |
glutamate ionotropic receptor NMDA type subunit associated protein 1 |
affects expression |
ISO |
Fluorouracil affects the expression of GRINA mRNA |
CTD |
PMID:16584549 |
|
NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
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G |
Gspt1 |
G1 to S phase transition 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of GSPT1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198
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G |
Gsr |
glutathione-disulfide reductase |
decreases activity |
ISO |
Fluorouracil results in decreased activity of GSR protein |
CTD |
PMID:32752303 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta4 |
glutathione S-transferase alpha 4 |
affects response to substance |
ISO |
GSTA4 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
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G |
Gstm1 |
glutathione S-transferase mu 1 |
multiple interactions |
ISO |
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of GSTM1 mRNA |
CTD |
PMID:32800223 |
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NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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G |
Gstp1 |
glutathione S-transferase pi 1 |
increases expression multiple interactions |
ISO |
Fluorouracil results in increased expression of GSTP1 mRNA [Cisplatin co-treated with Fluorouracil] results in decreased expression of GSTP1 mRNA; GSTP1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]; GSTP1 gene polymorphism results in decreased susceptibility to [Fluorouracil co-treated with Cisplatin] |
CTD |
PMID:15205334 PMID:15213713 PMID:15737843 PMID:16622263 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt1 |
glutathione S-transferase theta 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of GSTT1 protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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G |
Gtpbp4 |
GTP binding protein 4 |
affects response to substance |
ISO |
GTPBP4 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009
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G |
Gucy1b1 |
guanylate cyclase 1 soluble subunit beta 1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of GUCY1B1 mRNA |
CTD |
PMID:19219653 |
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NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
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G |
H1f0 |
H1.0 linker histone |
affects expression |
ISO |
Fluorouracil affects the expression of H1F0 mRNA |
CTD |
PMID:20421339 |
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NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
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G |
H2ax |
H2A.X variant histone |
affects expression multiple interactions increases phosphorylation |
ISO |
Fluorouracil affects the expression of H2AX mRNA [Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased expression of H2AX protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein]; TP53 gene mutant form affects the reaction [benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of H2AX mRNA] Fluorouracil results in increased phosphorylation of H2AX protein |
CTD |
PMID:15016801 PMID:16584549 PMID:25940438 PMID:26544897 PMID:34510228 |
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NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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G |
H2bc12 |
H2B clustered histone 12 |
decreases expression affects response to substance increases expression |
ISO |
Fluorouracil results in decreased expression of H2BC12 mRNA H2BC12 protein affects the susceptibility to Fluorouracil Fluorouracil results in increased expression of H2BC12 protein |
CTD |
PMID:15352031 PMID:16101138 PMID:16217747 |
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NCBI chr17:42,485,699...42,486,162
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G |
H3-7l |
H3.7 histone like |
decreases expression |
ISO |
Fluorouracil results in decreased expression of H3-7 mRNA |
CTD |
PMID:16101138 |
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NCBI chr 7:100,253,160...100,257,870
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G |
H4c14 |
H4 clustered histone 14 |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of H4C2 mRNA TP53 protein affects the reaction [Fluorouracil results in decreased expression of H4C2 mRNA] |
CTD |
PMID:15016801 PMID:17039268 |
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NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048
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G |
H4f3 |
H1.3 linker histone, cluster member |
increases expression |
ISO |
Fluorouracil results in increased expression of H1-3 protein |
CTD |
PMID:15585135 |
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NCBI chr17:41,551,524...41,552,303
Ensembl chr17:41,529,667...41,552,334
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G |
Hacd1 |
3-hydroxyacyl-CoA dehydratase 1 |
affects response to substance |
ISO |
HACD1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr17:77,081,508...77,106,114
Ensembl chr17:77,083,740...77,106,073
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G |
Hand1 |
heart and neural crest derivatives expressed 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HAND1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213
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G |
Hand2 |
heart and neural crest derivatives expressed 2 |
increases expression |
ISO |
Fluorouracil results in increased expression of HAND2 mRNA |
CTD |
PMID:24737281 |
|
NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891
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G |
Hapln2 |
hyaluronan and proteoglycan link protein 2 |
affects expression |
ISO |
Fluorouracil affects the expression of HAPLN2 mRNA |
CTD |
PMID:16584549 |
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NCBI chr 2:173,488,909...173,496,824
Ensembl chr 2:173,491,160...173,496,588
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G |
Hba-a2 |
hemoglobin alpha, adult chain 2 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HBA1 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
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G |
Hbb |
hemoglobin subunit beta |
affects splicing |
ISO |
Fluorouracil affects the splicing of HBB mRNA |
CTD |
PMID:17169984 |
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NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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G |
Hbb-b2 |
hemoglobin, beta adult minor chain |
increases expression |
ISO |
Fluorouracil results in increased expression of HBB-B2 protein |
CTD |
PMID:21296659 |
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NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012
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G |
Hbe1 |
hemoglobin subunit epsilon 1 |
decreases expression affects response to substance |
ISO |
Fluorouracil results in decreased expression of HBE1 protein HBE1 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15352031 |
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NCBI chr 1:158,282,931...158,458,855
Ensembl chr 1:158,282,936...158,284,391
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G |
Hbz |
hemoglobin subunit zeta |
decreases expression |
ISO |
Fluorouracil results in decreased expression of HBZ protein |
CTD |
PMID:21296659 |
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NCBI chr10:15,343,821...15,345,301
Ensembl chr10:15,343,831...15,345,312
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G |
Hdac1 |
histone deacetylase 1 |
multiple interactions |
ISO |
[HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC1 protein] |
CTD |
PMID:25178657 |
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NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
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G |
Hdac2 |
histone deacetylase 2 |
multiple interactions increases response to substance |
ISO |
[HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC2 protein] HDAC2 protein results in increased susceptibility to Fluorouracil |
CTD |
PMID:25178657 PMID:35608750 |
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NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
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G |
Hdac3 |
histone deacetylase 3 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of HDAC3 mRNA |
CTD |
PMID:19272435 |
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NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
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G |
Hdac4 |
histone deacetylase 4 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of HDAC4 mRNA |
CTD |
PMID:16557594 |
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NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
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G |
Hdac7 |
histone deacetylase 7 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of HDAC7 mRNA |
CTD |
PMID:26272751 |
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NCBI chr 7:128,923,918...128,961,926
Ensembl chr 7:128,923,920...128,962,072
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G |
Hdac9 |
histone deacetylase 9 |
increases expression |
ISO |
Fluorouracil results in increased expression of HDAC9 mRNA |
CTD |
PMID:24737281 |
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NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
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G |
Hdgfl3 |
HDGF like 3 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HDGFL3 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719
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G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HERPUD1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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G |
Hes1 |
hes family bHLH transcription factor 1 |
increases activity |
ISO |
Fluorouracil results in increased activity of HES1 protein |
CTD |
PMID:19147571 |
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NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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G |
Hgf |
hepatocyte growth factor |
increases expression |
ISO |
Fluorouracil results in increased expression of HGF mRNA |
CTD |
PMID:24737281 |
|
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hic2 |
HIC ZBTB transcriptional repressor 2 |
affects response to substance |
ISO |
HIC2 protein affects the susceptibility to Fluorouracil |
CTD |
PMID:16217747 |
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NCBI chr11:83,737,075...83,789,554
Ensembl chr11:83,738,874...83,767,484
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
affects localization multiple interactions increases expression decreases expression decreases uptake affects response to substance decreases response to substance |
ISO EXP |
Fluorouracil affects the localization of HIF1A protein [diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in increased expression of HIF1A protein]; Fluorouracil inhibits the reaction [Trichloroacetic Acid results in increased expression of HIF1A protein] Fluorouracil results in increased expression of HIF1A mRNA Fluorouracil results in decreased expression of HIF1A protein HIF1A protein results in decreased uptake of Fluorouracil HIF1A protein affects the susceptibility to Fluorouracil Fluorouracil results in decreased susceptibility to HIF1A protein; HIF1A results in decreased susceptibility to Fluorouracil Acetylcysteine inhibits the reaction [Fluorouracil affects the localization of HIF1A protein]; Cyclosporine inhibits the reaction [HIF1A protein results in decreased uptake of Fluorouracil] |
CTD |
PMID:16628086 PMID:17066447 PMID:17219956 PMID:27163855 PMID:34794354 PMID:37338137 More...
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hint1 |
histidine triad nucleotide binding protein 1 |
increases expression |
ISO |
Fluorouracil results in increased expression of HINT1 protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568
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G |
Hk2 |
hexokinase 2 |
decreases expression affects response to substance multiple interactions |
ISO |
Fluorouracil results in decreased expression of HK2 protein HK2 protein affects the susceptibility to Fluorouracil HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein] |
CTD |
PMID:16595493 PMID:18772588 |
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NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
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G |
Hm13 |
histocompatibility minor 13 |
affects expression |
ISO |
Fluorouracil affects the expression of HM13 mRNA |
CTD |
PMID:16584549 |
|
NCBI chr 3:141,145,792...141,183,557
Ensembl chr 3:141,145,782...141,184,703
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G |
Hmces |
5-hydroxymethylcytosine binding, ES cell specific |
affects response to substance |
ISO |
HMCES protein affects the susceptibility to Fluorouracil |
CTD |
PMID:15548681 |
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NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616
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G |
Hmg20b |
high mobility group 20 B |
decreases expression |
ISO |
Fluorouracil results in decreased expression of HMG20B mRNA |
CTD |
PMID:16709241 |
|
NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMG1 mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmgn5 |
high mobility group nucleosome binding domain 5 |
increases expression |
ISO |
Fluorouracil results in increased expression of HMGN5 mRNA |
CTD |
PMID:16510598 |
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NCBI chr X:74,085,871...74,094,488
Ensembl chr X:74,085,875...74,094,441
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G |
Hmmr |
hyaluronan-mediated motility receptor |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMMR mRNA] |
CTD |
PMID:15016801 |
|
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
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G |
Hmox1 |
heme oxygenase 1 |
increases expression affects expression |
ISO EXP |
Fluorouracil results in increased expression of HMOX1 Fluorouracil affects the expression of HMOX1 mRNA |
CTD |
PMID:20722640 PMID:22954530 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf1a |
HNF1 homeobox A |
affects expression |
ISO |
Fluorouracil affects the expression of HNF1A mRNA |
CTD |
PMID:34151400 |
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NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
affects expression |
ISO |
Fluorouracil affects the expression of HNF4A mRNA |
CTD |
PMID:34151400 |
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NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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G |
Hnrnpa1 |
heterogeneous nuclear ribonucleoprotein A1 |
decreases expression multiple interactions |
ISO |
Fluorouracil results in decreased expression of HNRNPA1 mRNA TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA1 mRNA] |
CTD |
PMID:15016801 PMID:16101138 |
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NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA2B1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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G |
Hnrnpc |
heterogeneous nuclear ribonucleoprotein C |
increases expression |
ISO |
Fluorouracil results in increased expression of HNRNPC protein |
CTD |
PMID:15585135 PMID:16803524 |
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NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
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G |
Hnrnpf |
heterogeneous nuclear ribonucleoprotein F |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPF mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 4:151,083,262...151,104,464
Ensembl chr 4:151,083,062...151,109,038
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G |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPH1 mRNA] |
CTD |
PMID:15016801 |
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NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
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G |
Hnrnpl |
heterogeneous nuclear ribonucleoprotein L |
multiple interactions |
ISO |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPL mRNA] |
CTD |
PMID:15016801 |
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NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553
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G |
Hoxa1 |
homeobox A1 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of HOXA1 mRNA |
CTD |
PMID:24737281 |
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NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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G |
Hoxb3 |
homeo box B3 |
decreases expression |
ISO |
Fluorouracil results in decreased expression of HOXB3 mRNA |
CTD |
PMID:24737281 |
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NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107
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