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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nucleobase analogue
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Accession:CHEBI:67142 term browser browse the term
Definition:A molecule that can substitute for a normal nucleobase in nucleic acids.
Synonyms:related_synonym: base analog;   base analogs;   base analogue;   base analogues;   nucleobase analog;   nucleobase analogs;   nucleobase analogues
 xref: Wikipedia:Base_analog


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2-aminopurine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ACP5 protein] CTD PMID:25739386 NCBI chr 8:20,663,984...20,670,604 JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions ISO 2-Aminopurine affects the reaction [LEP protein affects the expression of ADGRE1 mRNA] CTD PMID:24150608 NCBI chr 9:2,242,476...2,398,000 JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 protein] CTD PMID:25739386 NCBI chr 5:33,336,257...33,385,354 JBrowse link
G Calcr calcitonin receptor multiple interactions ISO 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of CALCR protein] CTD PMID:25739386 NCBI chr 4:31,661,270...31,736,392 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 2-Aminopurine inhibits the reaction [LEP protein affects the expression of CCL2 mRNA] CTD PMID:24150608 NCBI chr10:67,005,424...67,007,222 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO 2-Aminopurine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; 2-Aminopurine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:1312672 NCBI chr 8:58,096,021...58,102,130 JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases expression ISO 2-Aminopurine results in increased expression of CYP2A5 CTD PMID:11853694 NCBI chr 1:82,171,914...82,179,980 JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 decreases phosphorylation
decreases activity
multiple interactions
ISO 2-Aminopurine results in decreased phosphorylation of EIF2AK2 protein
2-Aminopurine results in decreased activity of EIF2AK2 protein
2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of EIF2AK2 protein]
2-Aminopurine inhibits the reaction [[IFNB1 results in increased expression of EIF2AK2 protein] which results in decreased susceptibility to Mercuric Chloride]
CTD PMID:12890478 PMID:16324719 PMID:25739386 NCBI chr 6:16,189,000...16,224,972 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of FOS protein]] CTD PMID:25739386 NCBI chr 6:105,121,170...105,124,036 JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO 2-Aminopurine inhibits the reaction [[IFNB1 results in increased expression of EIF2AK2 protein] which results in decreased susceptibility to Mercuric Chloride] CTD PMID:16324719 NCBI chr 5:103,020,969...103,021,523 JBrowse link
G Il6 interleukin 6 multiple interactions ISO 2-Aminopurine affects the reaction [LEP protein affects the expression of IL6 mRNA] CTD PMID:24150608 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Lep leptin multiple interactions ISO 2-Aminopurine affects the reaction [LEP protein affects the expression of ADGRE1 mRNA]; 2-Aminopurine affects the reaction [LEP protein affects the expression of IL6 mRNA]; 2-Aminopurine affects the reaction [LEP protein affects the expression of TNF mRNA]; 2-Aminopurine inhibits the reaction [LEP protein affects the expression of CCL2 mRNA] CTD PMID:24150608 NCBI chr 4:57,661,127...57,675,262 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:25739386 NCBI chr11:83,957,813...84,023,629 JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:25739386 NCBI chr 1:181,366,646...181,372,863 JBrowse link
G Matk megakaryocyte-associated tyrosine kinase multiple interactions ISO 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of MATK protein] CTD PMID:25739386 NCBI chr 7:8,456,990...8,465,947 JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO 2-Aminopurine inhibits the reaction [TNF protein affects the localization of NFATC1 protein]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]] CTD PMID:25739386 NCBI chr18:74,046,421...74,156,041 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO 2-Aminopurine inhibits the reaction [TNF protein affects the localization of NFKB1 protein] CTD PMID:25739386 NCBI chr 2:224,016,214...224,132,135 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] CTD PMID:25739386 NCBI chr 6:72,858,713...72,861,941 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 2-Aminopurine inhibits the reaction [TNF protein affects the localization of RELA protein] CTD PMID:25739386 NCBI chr 1:202,925,001...202,935,484 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2-Aminopurine affects the reaction [LEP protein affects the expression of TNF mRNA]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ACP5 protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of CALCR protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of MATK protein]; 2-Aminopurine inhibits the reaction [TNF protein affects the localization of NFATC1 protein]; 2-Aminopurine inhibits the reaction [TNF protein affects the localization of NFKB1 protein]; 2-Aminopurine inhibits the reaction [TNF protein affects the localization of RELA protein]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of FOS protein]]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]]; 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of EIF2AK2 protein]; 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; 2-Aminopurine inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] CTD PMID:24150608 PMID:25739386 NCBI chr20:3,622,011...3,624,629 JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ACP5 protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of CALCR protein]; 2-Aminopurine inhibits the reaction [[TNF protein co-treated with TNFSF11 protein] results in increased expression of MATK protein]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of FOS protein]]; 2-Aminopurine inhibits the reaction [TNF protein promotes the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]] CTD PMID:25739386 NCBI chr15:53,674,990...53,705,171 JBrowse link
5-(hydroxymethyl)cytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase decreases methylation ISO 5-hydroxymethylcytosine results in decreased methylation of ATM gene CTD PMID:30990028 NCBI chr 8:53,828,741...53,932,773 JBrowse link
G Cmahp cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene multiple interactions ISO [bisphenol A results in decreased methylation of CMAH intron] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr17:40,557,161...40,642,350 JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO DNMT1 protein promotes the reaction [bis(4-hydroxyphenyl)sulfone results in decreased abundance of 5-hydroxymethylcytosine]; DNMT1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine] CTD PMID:32105160 NCBI chr 8:19,440,611...19,486,659 JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO DNMT3A protein promotes the reaction [bis(4-hydroxyphenyl)sulfone results in decreased abundance of 5-hydroxymethylcytosine]; DNMT3A protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine] CTD PMID:32105160 NCBI chr 6:26,791,517...26,902,161 JBrowse link
G Esr1 estrogen receptor 1 decreases abundance
multiple interactions
ISO ESR1 protein results in decreased abundance of 5-hydroxymethylcytosine
ESR1 protein promotes the reaction [bis(4-hydroxyphenyl)sulfone results in decreased abundance of 5-hydroxymethylcytosine]; ESR1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]
CTD PMID:32105160 NCBI chr 1:41,106,335...41,499,104 JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO [Chloranil results in increased abundance of 5-hydroxymethylcytosine] which results in increased expression of FTL mRNA CTD PMID:24214992 NCBI chr 1:95,936,390...95,938,234 JBrowse link
G Gnas GNAS complex locus multiple interactions ISO [bisphenol A results in increased methylation of GNAS intron] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 3:163,071,003...163,136,350 JBrowse link
G Grb10 growth factor receptor bound protein 10 multiple interactions ISO [bisphenol A results in increased methylation of GRB10 intron] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr14:86,495,054...86,602,815 JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases abundance ISO IDH2 protein mutant form results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO [bisphenol A results in decreased methylation of KCNQ1 intron] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 1:198,291,711...198,624,683 JBrowse link
G Klf14 Kruppel-like factor 14 multiple interactions ISO [bisphenol A results in decreased methylation of KLF14 exon] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 4:59,554,011...59,556,933 JBrowse link
G Pde10a phosphodiesterase 10A multiple interactions ISO [bisphenol A results in increased methylation of PDE10A intron] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 1:51,765,743...52,218,086 JBrowse link
G Pde4d phosphodiesterase 4D multiple interactions ISO [bisphenol A results in increased methylation of PDE4D exon] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 2:40,014,933...41,529,190 JBrowse link
G Plagl1 PLAG1 like zinc finger 1 multiple interactions ISO [bisphenol A results in increased methylation of PLAGL1 exon] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 1:7,477,295...7,517,229 JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A multiple interactions ISO [bisphenol A results in decreased methylation of PPP1R9A intron] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 4:32,970,501...33,292,360 JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 multiple interactions ISO TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET1 protein affects the reaction [Chloranil results in increased chemical synthesis of 5-hydroxymethylcytosine] CTD PMID:24214992 NCBI chr20:25,761,042...25,840,926 JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 multiple interactions
increases abundance
ISO TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET2 protein affects the reaction [Chloranil results in increased chemical synthesis of 5-hydroxymethylcytosine]
TET2 protein results in increased abundance of 5-hydroxymethylcytosine
bis(4-hydroxyphenyl)sulfone promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine]; bisphenol A promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine]; TET2 protein inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in decreased abundance of 5-hydroxymethylcytosine]; TET2 protein inhibits the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]
CTD PMID:24214992 PMID:32105160 NCBI chr 2:221,988,645...222,072,813 JBrowse link
G Ubc ubiquitin C multiple interactions ISO [Chloranil results in increased abundance of 5-hydroxymethylcytosine] which results in increased expression of UBC mRNA CTD PMID:24214992 NCBI chr12:31,238,889...31,243,924 JBrowse link
5-fluorouracil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of AARS1 mRNA] CTD PMID:15016801 NCBI chr19:38,999,130...39,021,152 JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
decreases expression
ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 protein; [Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Fluorouracil; ABCB1 gene SNP affects the susceptibility to [Cisplatin co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]
Fluorouracil results in increased expression of ABCB1 protein
Fluorouracil results in decreased expression of ABCB1 mRNA
CTD PMID:12576456 PMID:15239124 PMID:17287894 PMID:21332314 PMID:21833476 PMID:32800223 NCBI chr 4:25,357,467...25,529,941 JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 decreases expression ISO Fluorouracil results in decreased expression of ABCB6 mRNA CTD PMID:20737486 NCBI chr 9:76,668,554...76,677,263 JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC1 mRNA; ABCC1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 PMID:32800223 NCBI chr10:528,961...655,179 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects response to substance
multiple interactions
ISO ABCC2 protein affects the susceptibility to Fluorouracil
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC2 mRNA
CTD PMID:16217747 PMID:32800223 NCBI chr 1:242,664,657...242,723,239 JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 decreases response to substance
multiple interactions
ISO ABCC5 protein results in decreased susceptibility to Fluorouracil
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [ABCC5 protein results in decreased susceptibility to Fluorouracil]; ABCC5 protein results in increased export of and results in decreased susceptibility to Fluorouracil
CTD PMID:15897250 PMID:19077464 NCBI chr11:80,473,809...80,567,257 JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects response to substance
increases expression
ISO ABCC6 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of ABCC6 protein
CTD PMID:15352031 NCBI chr 1:96,447,224...96,501,464 JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 protein; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; [Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 PMID:21712253 PMID:21833476 PMID:32800223 NCBI chr 4:87,676,241...87,802,757 JBrowse link
G Abhd12b abhydrolase domain containing 12B decreases expression ISO Fluorouracil results in decreased expression of ABHD12B mRNA CTD PMID:24737281 NCBI chr 6:88,668,748...88,696,166 JBrowse link
G Abi1 abl-interactor 1 increases expression ISO Fluorouracil results in increased expression of ABI1 mRNA CTD PMID:19272435 NCBI chr17:85,098,837...85,179,829 JBrowse link
G Abi2 abl-interactor 2 decreases expression ISO Fluorouracil results in decreased expression of ABI2 mRNA CTD PMID:19272435 NCBI chr 9:61,856,379...61,904,029 JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain increases expression ISO Fluorouracil results in increased expression of ACADL protein CTD PMID:15585135 PMID:16803524 NCBI chr 9:68,333,981...68,372,149 JBrowse link
G Ackr3 atypical chemokine receptor 3 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACKR3 mRNA] CTD PMID:15016801 NCBI chr 9:90,799,682...90,811,246 JBrowse link
G Acot13 acyl-CoA thioesterase 13 affects response to substance ISO ACOT13 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:40,240,378...40,252,851 JBrowse link
G Acot7 acyl-CoA thioesterase 7 affects response to substance ISO ACOT7 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 5:162,686,562...162,779,309 JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of SAH mRNA] CTD PMID:15016801 NCBI chr 1:174,133,260...174,159,966 JBrowse link
G Actb actin, beta decreases expression ISO Fluorouracil results in decreased expression of ACTB protein CTD PMID:21296659 NCBI chr12:11,663,112...11,666,697 JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression ISO Fluorouracil results in decreased expression of ACTC1 protein CTD PMID:21296659 NCBI chr 3:100,811,987...100,817,523 JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO Fluorouracil results in decreased expression of ACTG2 mRNA CTD PMID:16709241 NCBI chr 4:116,021,832...116,046,475 JBrowse link
G Acy1 aminoacylase 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACY1 mRNA] CTD PMID:15016801 NCBI chr 8:107,072,354...107,077,756 JBrowse link
G Adam10 ADAM metallopeptidase domain 10 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM10 mRNA] CTD PMID:15016801 NCBI chr 8:71,346,008...71,477,889 JBrowse link
G Adam3a ADAM metallopeptidase domain 3A multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM3A mRNA] CTD PMID:15016801 NCBI chr16:67,299,949...67,349,970 JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAMTS9 mRNA] CTD PMID:15016801 NCBI chr 4:125,290,633...125,462,988 JBrowse link
G Adcy9 adenylate cyclase 9 decreases expression ISO Fluorouracil results in decreased expression of ADCY9 mRNA CTD PMID:19219653 NCBI chr10:11,138,966...11,262,067 JBrowse link
G Add3 adducin 3 affects response to substance ISO ADD3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:252,147,341...252,255,126 JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 affects response to substance ISO ADGRG1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:10,003,963...10,041,122 JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 affects response to substance ISO ADGRG6 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:8,812,889...8,954,239 JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 affects response to substance ISO ADGRL2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:237,696,055...238,327,141 JBrowse link
G Adm adrenomedullin affects response to substance ISO ADM protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:164,745,484...164,747,655 JBrowse link
G Adss adenylosuccinate synthase decreases expression
increases expression
ISO Fluorouracil results in decreased expression of ADSS2 mRNA
Fluorouracil results in increased expression of ADSS2 protein
CTD PMID:15585135 PMID:16709241 PMID:16803524 NCBI chr13:89,769,240...89,799,577 JBrowse link
G Afp alpha-fetoprotein increases expression
decreases expression
ISO Fluorouracil results in increased expression of AFP protein
Fluorouracil results in decreased expression of AFP; Fluorouracil results in decreased expression of AFP mRNA
CTD PMID:20448262 PMID:21296659 PMID:26272751 NCBI chr14:17,573,412...17,591,476 JBrowse link
G Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 decreases expression ISO Fluorouracil results in decreased expression of AGAP3 mRNA CTD PMID:16709241 NCBI chr 4:10,674,064...10,724,848 JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of AGR2 mRNA] CTD PMID:15016801 NCBI chr 6:52,708,602...52,729,378 JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of AHNAK protein
AHNAK protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr 1:205,882,223...205,970,934 JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions
increases expression
ISO [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased expression of AIFM1 protein
Fluorouracil results in increased expression of AIFM1 protein
[Fluorouracil co-treated with casticin] results in increased expression of AIFM1 protein
CTD PMID:16168113 PMID:32270916 NCBI chr  X:127,650,223...127,689,356 JBrowse link
G Akap12 A-kinase anchoring protein 12 affects expression ISO Fluorouracil affects the expression of AKAP12 mRNA CTD PMID:16584549 NCBI chr 1:40,730,123...40,819,863 JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 affects expression ISO Fluorouracil affects the expression of AKR1B10 mRNA CTD PMID:16584549 NCBI chr 4:63,038,459...63,060,336 JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 affects response to substance ISO AKR1C2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:65,759,778...65,808,013 JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 affects expression
affects response to substance
ISO Fluorouracil affects the expression of AKR1C3 mRNA
AKR1C3 protein affects the susceptibility to Fluorouracil
CTD PMID:16217747 PMID:16584549 NCBI chr17:66,110,970...66,127,867 JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
affects phosphorylation
increases phosphorylation
ISO [Apigenin co-treated with Fluorouracil] results in decreased expression of AKT1 protein; AG 1879 inhibits the reaction [Fluorouracil results in increased phosphorylation of AKT1 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein; Nicotine affects the reaction [Fluorouracil affects the phosphorylation of AKT1 protein]
Fluorouracil inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein]
CTD PMID:16724238 PMID:17918158 PMID:18794807 PMID:19885610 PMID:24095863 NCBI chr 6:131,713,716...131,735,319 JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression ISO Fluorouracil results in increased expression of AKT2 protein CTD PMID:16803524 NCBI chr 1:82,877,228...82,933,828 JBrowse link
G Alb albumin multiple interactions ISO [Leucovorin co-treated with Cisplatin co-treated with Fluorouracil] results in decreased expression of ALB protein CTD PMID:20180123 NCBI chr14:17,607,397...17,622,814 JBrowse link
G Alcam activated leukocyte cell adhesion molecule affects response to substance
decreases expression
ISO ALCAM protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ALCAM protein
CTD PMID:15352031 NCBI chr11:48,336,123...48,536,296 JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects response to substance ISO ALDH1A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:218,000,470...218,152,962 JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 affects response to substance
decreases expression
ISO ALDH1A3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ALDH1A3 protein
CTD PMID:15352031 NCBI chr 1:119,982,272...120,017,416 JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 affects response to substance ISO ALDH3A2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:45,928,313...45,949,366 JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ALG3 mRNA] CTD PMID:15016801 NCBI chr11:80,300,487...80,306,014 JBrowse link
G Alkbh8 alkB homolog 8, tRNA methyltransferase decreases expression ISO Fluorouracil results in decreased expression of ALKBH8 mRNA CTD PMID:16510598 NCBI chr 6:378,779...449,382 JBrowse link
G Amfr autocrine motility factor receptor multiple interactions ISO AMFR mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr19:10,996,705...11,032,260 JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 decreases expression ISO Fluorouracil results in decreased expression of AMPD2 mRNA CTD PMID:19219653 NCBI chr 2:195,707,609...195,720,454 JBrowse link
G Amt aminomethyltransferase increases expression ISO Fluorouracil results in increased expression of AMT protein CTD PMID:15585135 PMID:16803524 NCBI chr 8:108,981,620...108,988,127 JBrowse link
G Ang angiogenin affects response to substance ISO ANG protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Angpt1 angiopoietin 1 multiple interactions
increases expression
ISO ANGPT1 protein promotes the reaction [Fluorouracil results in increased expression of IFNA1 protein]
Fluorouracil results in increased expression of ANGPT1 protein
CTD PMID:17786339 NCBI chr 7:73,528,345...73,783,953 JBrowse link
G Angpt2 angiopoietin 2 decreases expression
multiple interactions
ISO Fluorouracil results in decreased expression of ANGPT2 protein
ANGPT2 protein promotes the reaction [Fluorouracil results in decreased expression of IFNA1 protein]
CTD PMID:17786339 NCBI chr16:71,088,364...71,138,805 JBrowse link
G Angptl2 angiopoietin-like 2 multiple interactions ISO ANGPTL2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 3:16,517,185...16,547,024 JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Fluorouracil results in decreased expression of ANGPTL3 mRNA CTD PMID:32535746 NCBI chr 5:113,703,007...113,710,044 JBrowse link
G Angptl4 angiopoietin-like 4 affects response to substance ISO ANGPTL4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:14,550,288...14,557,797 JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Fluorouracil results in increased expression of ANKRD1 mRNA CTD PMID:17039268 NCBI chr 1:233,815,851...233,834,891 JBrowse link
G Ankrd11 ankyrin repeat domain 11 increases expression
affects expression
ISO Fluorouracil results in increased expression of ANKRD11 mRNA
Fluorouracil affects the expression of ANKRD11 mRNA
CTD PMID:16510598 PMID:16584549 NCBI chr19:50,940,284...51,098,962 JBrowse link
G Ankrd36 ankyrin repeat domain 36 increases expression ISO Fluorouracil results in increased expression of ANKRD36 mRNA CTD PMID:16510598 NCBI chr14:80,451,699...80,568,458 JBrowse link
G Anln anillin, actin binding protein decreases expression
multiple interactions
ISO Fluorouracil results in decreased expression of ANLN mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANLN mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of ANLN mRNA]
CTD PMID:15016801 PMID:17982676 NCBI chr 8:20,858,227...20,921,602 JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANP32E mRNA] CTD PMID:15016801 NCBI chr 2:183,472,600...183,489,057 JBrowse link
G Anxa1 annexin A1 affects response to substance
decreases expression
ISO ANXA1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ANXA1 protein
CTD PMID:15352031 PMID:16217747 NCBI chr 1:217,861,175...217,877,205 JBrowse link
G Anxa2 annexin A2 decreases response to substance
multiple interactions
increases expression
ISO ANXA2 mRNA results in decreased susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in increased expression of ANXA2 mRNA]
CTD PMID:15152939 NCBI chr 8:70,105,268...70,141,663 JBrowse link
G Anxa3 annexin A3 increases expression ISO Fluorouracil results in increased expression of ANXA3 mRNA CTD PMID:17039268 NCBI chr14:12,727,708...12,781,717 JBrowse link
G Anxa4 annexin A4 decreases expression ISO Fluorouracil results in decreased expression of ANXA4 mRNA CTD PMID:15109396 NCBI chr 4:119,184,378...119,241,183 JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 multiple interactions ISO [Fluorouracil co-treated with irinotecan] results in decreased expression of AP2S1 mRNA CTD PMID:16391804 NCBI chr 1:77,417,496...77,428,903 JBrowse link
G Ap3s1 adaptor related protein complex 3 subunit sigma 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of AP3S1 mRNA] CTD PMID:15016801 NCBI chr18:39,462,727...39,531,626 JBrowse link
G Ap4s1 adaptor related protein complex 4 subunit sigma 1 decreases expression ISO Fluorouracil results in decreased expression of AP4S1 mRNA CTD PMID:16510598 NCBI chr 6:69,133,403...69,174,488 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Fluorouracil results in increased expression of APAF1 mRNA CTD PMID:16557594 NCBI chr 7:25,494,143...25,579,540 JBrowse link
G Apba2 amyloid beta precursor protein binding family A member 2 affects response to substance ISO APBA2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:118,053,270...118,286,858 JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 affects response to substance ISO APBB2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:41,557,918...41,878,622 JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance ISO APEX1 protein mutant form results in increased susceptibility to Fluorouracil CTD PMID:19470598 NCBI chr15:24,144,595...24,146,785 JBrowse link
G Apob apolipoprotein B multiple interactions
decreases secretion
decreases expression
ISO ursodoxicoltaurine inhibits the reaction [Fluorouracil results in decreased expression of APOB mRNA]
Fluorouracil results in decreased secretion of APOB protein
CTD PMID:32535746 NCBI chr 6:30,844,386...30,883,983 JBrowse link
G Apoc1 apolipoprotein C1 affects response to substance ISO APOC1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:79,347,057...79,350,340 JBrowse link
G Apoc3 apolipoprotein C3 decreases expression
decreases secretion
ISO Fluorouracil results in decreased expression of APOC3 mRNA
Fluorouracil results in decreased secretion of APOC3 protein
CTD PMID:32535746 NCBI chr 8:46,531,478...46,533,658 JBrowse link
G Aqp9 aquaporin 9 increases uptake EXP AQP9 protein results in increased uptake of Fluorouracil CTD PMID:9733774 NCBI chr 8:71,797,231...71,837,485 JBrowse link
G Areg amphiregulin affects response to substance
increases expression
ISO AREG affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of AREG mRNA
CTD PMID:15067352 PMID:16709241 NCBI chr14:16,972,185...16,981,443 JBrowse link
G Arf1 ADP-ribosylation factor 1 multiple interactions ISO ARF1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr10:43,997,983...44,014,543 JBrowse link
G Arf3 ADP-ribosylation factor 3 affects response to substance ISO ARF3 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 7:129,886,082...129,912,022 JBrowse link
G Arfgap1 ADP-ribosylation factor GTPase activating protein 1 increases expression ISO Fluorouracil results in increased expression of ARFGAP1 protein CTD PMID:15331170 NCBI chr 3:168,084,560...168,099,948 JBrowse link
G Arid5b AT-rich interaction domain 5B affects response to substance ISO ARID5B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:20,307,731...20,490,746 JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C increases expression ISO Fluorouracil results in increased expression of ARL4C mRNA CTD PMID:16510598 NCBI chr 9:89,300,335...89,303,770 JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 multiple interactions ISO ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Cisplatin]; ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin] CTD PMID:22452940 NCBI chr 4:129,810,650...129,838,628 JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ARMCX1 mRNA] CTD PMID:15016801 NCBI chr  X:97,898,969...97,902,874 JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 decreases expression ISO Fluorouracil results in decreased expression of ARPC3 mRNA CTD PMID:16709241 NCBI chr12:34,172,780...34,186,651 JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 affects response to substance
multiple interactions
ISO ASAH1 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ASAH1 mRNA]
CTD PMID:15016801 PMID:16217747 NCBI chr16:50,966,404...50,997,827 JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions ISO [Fluorouracil co-treated with irinotecan] results in decreased expression of ASS1 mRNA CTD PMID:16391804 NCBI chr 3:14,747,355...14,796,909 JBrowse link
G Atf3 activating transcription factor 3 affects expression
multiple interactions
increases expression
ISO Fluorouracil affects the expression of ATF3 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of ATF3 mRNA]
Fluorouracil results in increased expression of ATF3 mRNA; Fluorouracil results in increased expression of ATF3 protein
CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:16557594 PMID:16709241 NCBI chr13:102,751,278...102,800,520 JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Fluorouracil results in increased expression of ATF4 protein CTD PMID:29879413 NCBI chr 7:111,804,135...111,806,457 JBrowse link
G Atg12 autophagy related 12 decreases expression ISO Fluorouracil results in decreased expression of ATG12 mRNA CTD PMID:16510598 NCBI chr18:39,452,247...39,462,424 JBrowse link
G Atoh8 atonal bHLH transcription factor 8 affects expression ISO Fluorouracil affects the expression of ATOH8 mRNA CTD PMID:16584549 NCBI chr 4:104,259,992...104,292,168 JBrowse link
G Atp5f1d ATP synthase F1 subunit delta multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATP5F1D mRNA] CTD PMID:15016801 NCBI chr 7:9,560,604...9,565,919 JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions ISO ATP5PO mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr11:31,165,218...31,171,530 JBrowse link
G Atp7b ATPase copper transporting beta increases response to substance ISO ATP7B mRNA results in increased susceptibility to Fluorouracil CTD PMID:18593893 NCBI chr16:69,952,286...70,024,404 JBrowse link
G Atp9a ATPase phospholipid transporting 9A (putative) decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of ATP9A protein
ATP9A protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr 3:157,360,354...157,467,628 JBrowse link
G Atxn10 ataxin 10 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATXN10 mRNA] CTD PMID:15016801 NCBI chr 7:116,441,768...116,565,093 JBrowse link
G Aurka aurora kinase A decreases expression ISO Fluorouracil results in decreased expression of AURKA mRNA CTD PMID:15205334 PMID:16557594 PMID:16709241 PMID:17039268 PMID:19272435 NCBI chr 3:161,128,309...161,144,524 JBrowse link
G Aven apoptosis and caspase activation inhibitor decreases expression
increases expression
ISO Fluorouracil results in decreased expression of AVEN mRNA
Fluorouracil results in increased expression of AVEN mRNA
CTD PMID:16510598 PMID:16709241 NCBI chr 3:99,299,009...99,431,635 JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAD mRNA] CTD PMID:31129132 NCBI chr 1:204,133,502...204,142,829 JBrowse link
G Bag3 BAG cochaperone 3 affects response to substance ISO BAG3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:183,103,038...183,126,862 JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression
multiple interactions
increases response to substance
ISO Fluorouracil results in increased expression of BAK1; Fluorouracil results in increased expression of BAK1 mRNA; Fluorouracil results in increased expression of BAK1 protein
mithramycin A inhibits the reaction [Fluorouracil results in increased expression of BAK1 protein]
BAK1 mRNA results in increased susceptibility to Fluorouracil
CTD PMID:9792140 PMID:15489892 PMID:16557594 PMID:18593893 NCBI chr20:5,100,480...5,109,669 JBrowse link
G Barx2 BARX homeobox 2 increases expression ISO Fluorouracil results in increased expression of BARX2 protein CTD PMID:15585135 PMID:16803524 NCBI chr 8:30,251,132...30,319,105 JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects expression
increases expression
decreases expression
increases response to substance
ISO
EXP
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX protein; [Docosahexaenoic Acids co-treated with Fluorouracil] results in increased expression of BAX mRNA; [Fluorouracil co-treated with gamma-Tocopherol] results in increased expression of BAX mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in increased expression of BAX protein; [SM-1 compound co-treated with Fluorouracil] results in increased expression of BAX protein; [wogonin co-treated with Fluorouracil] results in increased expression of BAX protein; Aspirin promotes the reaction [Fluorouracil results in increased expression of BAX protein]; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of BAX mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of BAX mRNA]; Fluorouracil affects the reaction [rebamipide results in decreased expression of BAX protein]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of BAX protein]; Fluorouracil promotes the reaction [andrographolide affects the folding of BAX protein]; Fluorouracil promotes the reaction [Aspirin results in increased expression of BAX protein]; Fluorouracil promotes the reaction [Plant Extracts results in increased expression of BAX protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]; rebamipide inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; SM-1 compound promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]
Fluorouracil results in increased expression of BAX; Fluorouracil results in increased expression of BAX mRNA; Fluorouracil results in increased expression of BAX protein
[Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in increased expression of BAX protein; casticin inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; IL1RN protein affects the reaction [Fluorouracil results in increased expression of BAX protein]
Fluorouracil results in decreased expression of BAX protein
BAX protein results in increased susceptibility to Fluorouracil
CTD PMID:9388485 PMID:9792140 PMID:11062132 PMID:11750847 PMID:12442003 PMID:15641988 PMID:15754201 PMID:15986848 PMID:16168113 PMID:16686938 PMID:16888818 PMID:17045692 PMID:17056233 PMID:17589894 PMID:18567086 PMID:18834353 PMID:19015929 PMID:19097688 PMID:19116755 PMID:20570612 PMID:20844880 PMID:22525470 PMID:23941782 PMID:25824412 PMID:28599477 PMID:29054700 PMID:31129132 PMID:31587439 PMID:32270916 PMID:32800223 NCBI chr 1:95,940,001...95,945,407 JBrowse link
G Bbc3 Bcl-2 binding component 3 increases response to substance
multiple interactions
increases expression
ISO BBC3 protein results in increased susceptibility to Fluorouracil
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BBC3 mRNA; mithramycin A inhibits the reaction [Fluorouracil results in increased expression of BBC3 protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 protein]
Fluorouracil results in increased expression of BBC3 mRNA; Fluorouracil results in increased expression of BBC3 protein
CTD PMID:14665630 PMID:15016801 PMID:15489892 PMID:16481741 PMID:16557594 PMID:22525470 PMID:32800223 NCBI chr 1:77,013,281...77,022,509 JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 multiple interactions ISO BBS4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 8:59,731,912...59,765,408 JBrowse link
G Bbx BBX high mobility group box domain containing affects response to substance ISO BBX protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:50,381,249...50,628,934 JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of BCAR3 protein
BCAR3 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr 2:210,525,260...210,638,674 JBrowse link
G Bcat1 branched chain amino acid transaminase 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of BCAT1 mRNA] CTD PMID:15016801 NCBI chr 4:177,964,834...178,046,573 JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha affects expression ISO Fluorouracil affects the expression of BCKDHA mRNA CTD PMID:16584549 NCBI chr 1:81,138,946...81,167,765 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
affects expression
affects response to substance
decreases expression
increases expression
increases phosphorylation
decreases response to substance
ISO
EXP
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 protein; [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with Irinotecan] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with Irinotecan] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 protein; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BCL2 mRNA; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BCL2 protein; [wogonin co-treated with Fluorouracil] results in decreased expression of BCL2 protein; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA]; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of BCL2 protein]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of BCL2 mRNA]; Fluorouracil affects the reaction [rebamipide results in increased expression of BCL2 protein]; Fluorouracil promotes the reaction [gambogic acid results in decreased expression of BCL2 mRNA]; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 mRNA]; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; rebamipide inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; SM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BCL2 mRNA]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]
BCL2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of BCL2 mRNA
[Fluorouracil co-treated with casticin] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in decreased expression of BCL2 protein; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]
Fluorouracil results in increased phosphorylation of BCL2 protein
Fluorouracil results in decreased expression of BCL2; Fluorouracil results in decreased expression of BCL2 mRNA; Fluorouracil results in decreased expression of BCL2 protein
BCL2 protein results in decreased susceptibility to Fluorouracil
CTD PMID:7654318 PMID:9388485 PMID:14503796 PMID:15177426 PMID:15754201 PMID:15996812 PMID:16332177 PMID:16391804 PMID:16407826 PMID:16412276 PMID:16557594 PMID:16596200 PMID:16603448 PMID:16888818 PMID:16929163 PMID:17287894 PMID:17439414 PMID:17589894 PMID:18161298 PMID:18205257 PMID:18567086 PMID:18949393 PMID:19015929 PMID:19084572 PMID:20570612 PMID:20844880 PMID:23941782 PMID:28599477 PMID:29054700 PMID:31129132 PMID:31587439 PMID:32270916 PMID:32800223 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
affects response to substance
increases expression
decreases expression
affects expression
decreases response to substance
ISO
EXP
3-methyladenine inhibits the reaction [Fluorouracil results in increased expression of BCL2L1 protein]; [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of BCL2L1 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 protein; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA]; BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]; Fluorouracil affects the reaction [rebamipide results in increased expression of BCL2L1 protein]; gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 mRNA]; gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 protein]; IFNA1 promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 mRNA]; rebamipide inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 protein]
BCL2L1 protein affects the susceptibility to Fluorouracil
3-methyladenine inhibits the reaction [Fluorouracil results in increased expression of BCL2L1 protein]; casticin promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]; Fluorouracil promotes the reaction [casticin results in decreased expression of BCL2L1 protein]; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]
Fluorouracil results in increased expression of BCL2L1 mRNA; Fluorouracil results in increased expression of BCL2L1 protein
Fluorouracil results in decreased expression of BCL2L1; Fluorouracil results in decreased expression of BCL2L1 mRNA; Fluorouracil results in decreased expression of BCL2L1 protein
Fluorouracil affects the expression of BCL2L1 mRNA; Fluorouracil affects the expression of BCL2L1 protein
BCL2L1 protein results in decreased susceptibility to Fluorouracil
CTD PMID:12442003 PMID:15289866 PMID:15767554 PMID:16407826 PMID:16557594 PMID:16596200 PMID:16875599 PMID:16929163 PMID:17033717 PMID:17045692 PMID:17399942 PMID:17439414 PMID:19116755 PMID:20844880 PMID:21474236 PMID:29054700 PMID:29879413 PMID:31129132 PMID:32270916 NCBI chr 3:141,253,508...141,304,582 JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions
increases expression
ISO Fluorouracil affects the reaction [rebamipide results in decreased expression of BCL2L11 protein]; rebamipide inhibits the reaction [Fluorouracil results in increased expression of BCL2L11 protein] CTD PMID:29054700 NCBI chr 3:115,366,783...115,404,068 JBrowse link
G Bcl2l12 BCL2 like 12 multiple interactions ISO [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of BCL2L12 mRNA CTD PMID:19015929 NCBI chr 1:95,472,272...95,480,991 JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO Fluorouracil results in decreased expression of BDH1 protein CTD PMID:15585135 PMID:16803524 NCBI chr11:69,302,534...69,343,173 JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of BDKRB2 mRNA] CTD PMID:15016801 NCBI chr 6:124,472,317...124,502,497 JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression EXP Fluorouracil results in decreased expression of BDNF protein CTD PMID:18702703 NCBI chr 3:96,165,042...96,215,621 JBrowse link
G Bean1 brain expressed, associated with NEDD4, 1 increases expression
affects response to substance
ISO Fluorouracil results in increased expression of BEAN1 protein
BEAN1 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr19:739,551...786,122 JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
ISO BECN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
Apigenin promotes the reaction [Fluorouracil results in increased expression of BECN1 protein]; Fluorouracil promotes the reaction [Apigenin results in increased expression of BECN1 protein]
CTD PMID:16896004 PMID:28025107 NCBI chr10:86,231,387...86,246,742 JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression EXP Fluorouracil results in increased expression of BGLAP mRNA CTD PMID:16888818 NCBI chr 2:173,838,518...173,839,495 JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 affects response to substance ISO BHLHE41 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:178,833,085...178,838,685 JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases expression
decreases response to substance
decreases expression
increases response to substance
ISO [Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of BID protein; BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]; Fluorouracil results in increased cleavage of and results in increased activity of BID protein; IFNA1 promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of BID protein]
Fluorouracil results in increased expression of BID protein
casticin inhibits the reaction [Fluorouracil results in increased expression of BID protein]
BID protein mutant form results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BID protein
CTD PMID:15095271 PMID:15289866 PMID:15754201 PMID:21474236 PMID:32270916 NCBI chr 4:154,113,198...154,136,353 JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO Fluorouracil results in increased expression of BIRC2 mRNA CTD PMID:17039268 NCBI chr 8:4,968,856...4,989,325 JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO Fluorouracil results in increased expression of BIRC3 mRNA CTD PMID:16557594 NCBI chr 8:5,000,844...5,028,470 JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases response to substance
increases expression
decreases expression
multiple interactions
affects response to substance
ISO BIRC5 protein results in decreased susceptibility to Fluorouracil; BIRC5 results in decreased susceptibility to Fluorouracil
Fluorouracil results in increased expression of BIRC5 mRNA; Fluorouracil results in increased expression of BIRC5 protein
Fluorouracil results in decreased expression of BIRC5 mRNA; Fluorouracil results in decreased expression of BIRC5 protein
[Fluorouracil co-treated with RNF34 protein] results in increased expression of BIRC5 protein; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BIRC5 mRNA; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 mRNA]; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 protein]; SM-1 compound inhibits the reaction [Fluorouracil results in increased expression of BIRC5 mRNA]; SM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BIRC5 protein]
BIRC5 affects the susceptibility to Fluorouracil; BIRC5 protein affects the susceptibility to Fluorouracil
CTD PMID:15067352 PMID:15109396 PMID:15685548 PMID:16217747 PMID:16546719 PMID:16596200 PMID:16709241 PMID:16929163 PMID:17399942 PMID:18714155 PMID:19618606 PMID:28599477 PMID:29054700 NCBI chr10:103,072,530...103,081,382 JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 affects response to substance
decreases response to substance
ISO BIRC6 protein affects the susceptibility to Fluorouracil
BIRC6 results in decreased susceptibility to Fluorouracil
CTD PMID:18239605 PMID:21542283 NCBI chr 6:20,722,922...20,916,396 JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 decreases response to substance ISO BIRC7 protein results in decreased susceptibility to Fluorouracil CTD PMID:17437058 NCBI chr 3:168,047,824...168,052,606 JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Fluorouracil results in decreased expression of BLM mRNA CTD PMID:19272435 NCBI chr 1:134,409,832...134,496,073 JBrowse link
G Blvrb biliverdin reductase B affects response to substance ISO BLVRB protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:82,738,646...82,756,312 JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Fluorouracil results in increased expression of BNIP1 mRNA CTD PMID:33770205 NCBI chr10:16,386,876...16,399,124 JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
affects response to substance
ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of BNIP3 mRNA]
BNIP3 affects the susceptibility to Fluorouracil
CTD PMID:15016801 PMID:15067352 NCBI chr 1:193,708,164...193,725,348 JBrowse link
G Bnip3l BCL2 interacting protein 3 like affects response to substance
decreases expression
increases expression
ISO BNIP3L affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BNIP3L mRNA
Fluorouracil results in increased expression of BNIP3L mRNA
CTD PMID:15067352 PMID:15109396 PMID:16557594 PMID:16709241 PMID:17039268 NCBI chr15:41,174,594...41,197,730 JBrowse link
G Boll boule homolog, RNA binding protein multiple interactions ISO BOLL mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 9:56,734,890...56,859,917 JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of BOP1 mRNA] CTD PMID:15016801 NCBI chr 7:108,172,062...108,195,875 JBrowse link
G Bora bora, aurora kinase A activator decreases expression ISO Fluorouracil results in decreased expression of BORA mRNA CTD PMID:17374387 NCBI chr15:75,797,624...75,835,599 JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression
decreases expression
multiple interactions
ISO Fluorouracil results in increased expression of BRCA1 mRNA
Fluorouracil results in decreased expression of BRCA1 mRNA
TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of BRCA1 mRNA]
CTD PMID:15607317 PMID:16101138 PMID:16557594 PMID:17982676 NCBI chr10:86,417,441...86,477,762 JBrowse link
G Brix1 biogenesis of ribosomes BRX1 decreases expression ISO Fluorouracil results in decreased expression of BRIX1 mRNA CTD PMID:16510598 NCBI chr 2:59,450,608...59,461,486 JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression
multiple interactions
ISO Fluorouracil results in increased expression of BTG2 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of BTG2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of BTG2 mRNA]
CTD PMID:15016801 PMID:17982676 NCBI chr13:45,531,881...45,535,642 JBrowse link
G Btg3 BTG anti-proliferation factor 3 multiple interactions ISO BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr11:17,030,156...17,046,069 JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Fluorouracil results in decreased expression of BUB1 mRNA CTD PMID:16709241 PMID:19272435 NCBI chr 3:115,020,254...115,051,650 JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Fluorouracil results in decreased expression of BUB1B mRNA CTD PMID:16557594 PMID:16709241 PMID:19272435 NCBI chr 3:105,563,089...105,615,547 JBrowse link
G Bub3 BUB3 mitotic checkpoint protein affects response to substance
decreases expression
ISO BUB3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BUB3 protein
CTD PMID:15548681 PMID:15585135 PMID:16803524 NCBI chr 1:186,330,358...186,340,969 JBrowse link
G C4bpb complement component 4 binding protein, beta affects expression ISO Fluorouracil affects the expression of C4BPB mRNA CTD PMID:16584549 NCBI chr13:42,120,798...42,131,515 JBrowse link
G Ca12 carbonic anhydrase 12 multiple interactions ISO CA12 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 8:67,274,739...67,330,428 JBrowse link
G Ca14 carbonic anhydrase 14 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CA14 mRNA] CTD PMID:15016801 NCBI chr 2:183,442,263...183,449,207 JBrowse link
G Cabyr calcium binding tyrosine phosphorylation regulated affects response to substance ISO CABYR protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr18:3,892,062...3,904,391 JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CAD mRNA] CTD PMID:15016801 NCBI chr 6:25,292,133...25,315,176 JBrowse link
G Calb2 calbindin 2 increases response to substance
increases expression
ISO CALB2 protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of CALB2 mRNA
CTD PMID:16510598 NCBI chr19:38,114,435...38,141,438 JBrowse link
G Canx calnexin multiple interactions ISO CANX results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CANX mRNA] CTD PMID:15016801 PMID:18678097 NCBI chr10:34,623,865...34,656,866 JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 affects response to substance ISO CAP2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:18,054,234...18,203,453 JBrowse link
G Casd1 CAS1 domain containing 1 affects expression ISO Fluorouracil affects the expression of CASD1 mRNA CTD PMID:20421339 NCBI chr 4:32,658,888...32,739,224 JBrowse link
G Casp1 caspase 1 increases cleavage ISO Fluorouracil results in increased cleavage of CASP1 protein CTD PMID:15162350 NCBI chr 8:2,587,812...2,597,403 JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
decreases cleavage
increases cleavage
decreases expression
ISO
EXP
Fluorouracil results in increased expression of CASP3; Fluorouracil results in increased expression of CASP3 mRNA; Fluorouracil results in increased expression of CASP3 protein; Fluorouracil results in increased expression of CASP3 protein modified form
Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]
Fluorouracil results in increased activity of CASP3 protein
Fluorouracil results in decreased cleavage of CASP3 protein
3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein]; [10-hydroxycamptothecin co-treated with Fluorouracil co-treated with Leucovorin] results in increased activity of CASP3 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 protein; [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP3 protein; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP3; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP3 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP3 protein; [Fluorouracil co-treated with IFNB1 protein] results in increased activity of CASP3 protein; [Fluorouracil co-treated with olaparib] results in increased cleavage of CASP3 protein; [Fluorouracil co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased activity of CASP3 protein; [SM-1 compound co-treated with Fluorouracil] results in increased cleavage of CASP3 protein; [wogonin co-treated with Fluorouracil] results in increased activity of CASP3 protein; Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]]; Celecoxib inhibits the reaction [Fluorouracil results in increased expression of CASP3 protein]; Drugs, Chinese Herbal promotes the reaction [Fluorouracil results in increased cleavage of and results in increased expression of CASP3 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP3 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [Drugs, Chinese Herbal results in increased cleavage of and results in increased expression of CASP3 protein]; Fluorouracil promotes the reaction [gambogic acid results in decreased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [temsirolimus results in increased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP3 protein]; Fluorouracil results in increased activity of and results in increased cleavage of CASP3 protein; Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein; Fluorouracil results in increased cleavage of and results in increased expression of CASP3 protein; HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFI6 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [Fluorouracil results in decreased cleavage of CASP3 protein]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CASP3 mRNA]; temsirolimus promotes the reaction [Fluorouracil results in increased expression of CASP3 mRNA]; TNFRSF10B mutant form inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]
Fluorouracil results in decreased expression of CASP3 mRNA
3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein]; Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; casticin inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [Apigenin results in increased activity of CASP3 protein]; Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein; IL1RN protein affects the reaction [Fluorouracil results in increased expression of CASP3 protein modified form]
CTD PMID:10891390 PMID:11300326 PMID:12414664 PMID:12934351 PMID:12941601 PMID:14503796 PMID:15120327 PMID:15282376 PMID:15585135 PMID:15685448 PMID:16080519 PMID:16168113 PMID:16407826 PMID:16803524 PMID:17016659 PMID:17056233 PMID:17219956 PMID:17399942 PMID:17461495 PMID:17498489 PMID:17589894 PMID:18161298 PMID:18205257 PMID:18608205 PMID:18772588 PMID:18830594 PMID:19084572 PMID:19097688 PMID:19116755 PMID:19764996 PMID:19815060 PMID:19816940 PMID:19885610 PMID:19928967 PMID:20570612 PMID:20844880 PMID:20876774 PMID:21036698 PMID:21461573 PMID:25940438 PMID:26310874 PMID:26544897 PMID:28025107 PMID:28599477 PMID:29678497 PMID:31129132 PMID:31288002 PMID:32270916 PMID:32634519 PMID:32800223 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Casp4 caspase 4 increases expression
affects response to substance
ISO Fluorouracil results in increased expression of CASP4 protein
CASP4 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 PMID:16217747 NCBI chr 8:2,599,017...2,635,097 JBrowse link
G Casp6 caspase 6 multiple interactions ISO Fluorouracil results in increased cleavage of and results in increased activity of CASP6 protein; resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]; TP53 affects the reaction [resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]] CTD PMID:18497562 NCBI chr 2:218,466,063...218,478,503 JBrowse link
G Casp7 caspase 7 multiple interactions
increases cleavage
ISO [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 protein
Fluorouracil results in increased cleavage of CASP7 protein
CTD PMID:16168113 PMID:26544897 NCBI chr 1:255,437,195...255,476,737 JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
increases cleavage
decreases expression
increases expression
ISO [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CASP8 protein; [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP8 protein; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP8; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP8 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP8 protein; [Fluorouracil co-treated with olaparib] results in increased cleavage of CASP8 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased cleavage of CASP8 protein]; Cadmium Chloride affects the reaction [Fluorouracil results in decreased expression of CASP8 mRNA]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]]; CASP8 results in increased susceptibility to [andrographolide co-treated with Fluorouracil]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP8 protein]; Fluorouracil affects the reaction [Cadmium Chloride results in decreased expression of CASP8 mRNA]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP8 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP8 protein]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP8 protein]; IFNA1 promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP8 protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Fluorouracil results in increased activity of CASP8 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]
Fluorouracil results in increased cleavage of CASP8 protein
Fluorouracil results in increased expression of CASP8 mRNA; Fluorouracil results in increased expression of CASP8 protein
CTD PMID:10779637 PMID:10891390 PMID:12414664 PMID:14607657 PMID:15585135 PMID:16168113 PMID:16803524 PMID:17016659 PMID:17056233 PMID:17637740 PMID:18830594 PMID:19097688 PMID:19816940 PMID:19928967 PMID:20876774 PMID:21474236 PMID:23941782 PMID:26544897 PMID:32270916 NCBI chr 9:60,263,863...60,312,542 JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
decreases expression
increases expression
increases cleavage
ISO
EXP
[Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of CASP9 mRNA; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP9; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP9 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP9 protein; Cadmium Chloride promotes the reaction [Fluorouracil results in decreased expression of CASP9 mRNA]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP9 protein]; Fluorouracil inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 mRNA]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP9 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [Arsenic Trioxide results in decreased expression of CASP9 protein]; Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]; TP53 protein inhibits the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein]
Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; casticin promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [Apigenin results in increased activity of CASP9 protein]
Fluorouracil results in increased expression of CASP9 protein
Fluorouracil results in increased cleavage of CASP9 protein
CTD PMID:10779637 PMID:12414664 PMID:15546879 PMID:15996812 PMID:16168113 PMID:16407826 PMID:16803524 PMID:17016659 PMID:17056233 PMID:17498489 PMID:18830594 PMID:19015929 PMID:19097688 PMID:19816940 PMID:19928967 PMID:22963400 PMID:23941782 PMID:28025107 PMID:31129132 PMID:32270916 NCBI chr 5:154,108,872...154,126,628 JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO Fluorouracil inhibits the reaction [casticin results in increased expression of CAT protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Fluorouracil promotes the reaction [Luteolin results in decreased activity of CAT protein]; Luteolin promotes the reaction [Fluorouracil results in decreased activity of CAT protein] CTD PMID:27836789 PMID:31288002 PMID:32270916 PMID:32752303 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Cav1 caveolin 1 affects response to substance
increases expression
decreases expression
ISO CAV1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CAV1 mRNA
Fluorouracil results in decreased expression of CAV1 protein
CTD PMID:15352031 PMID:24737281 NCBI chr 4:45,640,624...45,673,708 JBrowse link
G Cav2 caveolin 2 decreases expression
increases expression
ISO Fluorouracil results in decreased expression of CAV2 mRNA
Fluorouracil results in increased expression of CAV2 mRNA
CTD PMID:16510598 PMID:24737281 NCBI chr 4:45,616,766...45,624,144 JBrowse link
G Cbr3 carbonyl reductase 3 affects expression ISO Fluorouracil affects the expression of CBR3 mRNA CTD PMID:20421339 NCBI chr11:33,008,615...33,016,877 JBrowse link
G Cbs cystathionine beta synthase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CBS mRNA] CTD PMID:15016801 NCBI chr20:9,708,089...9,732,623 JBrowse link
G Cbx1 chromobox 1 affects response to substance ISO CBX1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:81,770,307...81,789,981 JBrowse link
G Ccdc186 coiled-coil domain containing 186 increases expression ISO Fluorouracil results in increased expression of CCDC186 mRNA CTD PMID:16510598 NCBI chr 1:255,831,663...255,871,954 JBrowse link
G Ccn1 cellular communication network factor 1 increases expression
affects response to substance
ISO Fluorouracil results in increased expression of CCN1 mRNA; Fluorouracil results in increased expression of CCN1 protein
CCN1 affects the susceptibility to Fluorouracil
CTD PMID:15067352 PMID:17699798 PMID:24737281 NCBI chr 2:234,562,410...234,565,370 JBrowse link
G Ccn2 cellular communication network factor 2 affects expression ISO Fluorouracil affects the expression of CCN2 mRNA CTD PMID:15205334 NCBI chr 1:20,802,199...20,805,315 JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Fluorouracil results in increased expression of CCN3 mRNA CTD PMID:16510598 NCBI chr 7:86,094,000...86,101,022 JBrowse link
G Ccna1 cyclin A1 multiple interactions
affects expression
ISO [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CCNA1 protein; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of CCNA1 mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of CCNA1 mRNA]
Fluorouracil affects the expression of CCNA1 mRNA; Fluorouracil affects the expression of CCNA1 protein
CTD PMID:23941782 NCBI chr 2:139,231,738...139,278,066 JBrowse link
G Ccna2 cyclin A2 multiple interactions
affects response to substance
affects expression
decreases expression
ISO N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNA2 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]]
CCNA2 protein affects the susceptibility to Fluorouracil
Fluorouracil affects the expression of CCNA2 mRNA
Fluorouracil results in decreased expression of CCNA2 mRNA; Fluorouracil results in decreased expression of CCNA2 protein
CTD PMID:15205334 PMID:15546879 PMID:15548681 PMID:16557594 PMID:18383818 NCBI chr 2:119,427,239...119,433,645 JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression
ISO N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]
Fluorouracil results in decreased expression of CCNB1 mRNA; Fluorouracil results in decreased expression of CCNB1 protein
CTD PMID:15016801 PMID:15205334 PMID:15546879 PMID:16557594 PMID:17982676 NCBI chr 2:31,912,190...31,921,163 JBrowse link
G Ccnb2 cyclin B2 multiple interactions
decreases expression
ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB2 mRNA]
Fluorouracil results in decreased expression of CCNB2 mRNA; Fluorouracil results in decreased expression of CCNB2 protein
CTD PMID:15016801 PMID:16557594 PMID:16709241 PMID:17982488 PMID:19272435 NCBI chr 8:71,087,594...71,100,794 JBrowse link
G Ccnc cyclin C decreases expression ISO Fluorouracil results in decreased expression of CCNC mRNA CTD PMID:16709241 NCBI chr 5:35,266,828...35,284,943 JBrowse link
G Ccnd1 cyclin D1 affects response to substance
multiple interactions
decreases expression
affects expression
ISO CCND1 protein affects the susceptibility to Fluorouracil
Fluorouracil promotes the reaction [Luteolin results in decreased expression of CCND1 protein]; Luteolin promotes the reaction [Fluorouracil results in decreased expression of CCND1 protein]
Fluorouracil affects the expression of CCND1 mRNA; Fluorouracil affects the expression of CCND1 protein
Fluorouracil results in decreased expression of CCND1 mRNA; Fluorouracil results in decreased expression of CCND1 protein
[allose co-treated with Fluorouracil] results in decreased expression of CCND1 protein; [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CCND1 protein; [Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCND1 mRNA; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of CCND1 mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of CCND1 mRNA]; Fluorouracil promotes the reaction [allose results in decreased expression of CCND1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCND1 protein]
CTD PMID:15352031 PMID:17982676 PMID:18930000 PMID:23941782 PMID:31288002 PMID:31587439 NCBI chr 1:200,089,002...200,098,524 JBrowse link
G Ccnd2 cyclin D2 increases expression
decreases expression
multiple interactions
affects response to substance
ISO Fluorouracil results in increased expression of CCND2 protein
Fluorouracil results in decreased expression of CCND2 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCND2 mRNA]
CCND2 protein affects the susceptibility to Fluorouracil
CTD PMID:15016801 PMID:15352031 PMID:19272435 NCBI chr 4:159,966,883...159,989,261 JBrowse link
G Ccnd3 cyclin D3 affects response to substance
increases expression
ISO CCND3 affects the susceptibility to Fluorouracil; CCND3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CCND3 mRNA
CTD PMID:15067352 PMID:15548681 PMID:16709241 PMID:18383818 NCBI chr 9:13,394,161...13,400,341 JBrowse link
G Ccne1 cyclin E1 decreases expression
multiple interactions
increases expression
ISO Fluorouracil results in decreased expression of CCNE1 mRNA
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCNE1 mRNA; [Leucovorin co-treated with Fluorouracil] results in increased expression of CCNE1 mRNA
Fluorouracil results in increased expression of CCNE1 mRNA; Fluorouracil results in increased expression of CCNE1 protein
CTD PMID:9930367 PMID:15342418 PMID:16101138 PMID:18930000 PMID:31587439 NCBI chr 1:90,781,947...90,791,188 JBrowse link
G Ccne2 cyclin E2 affects response to substance ISO CCNE2 affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr 5:24,285,078...24,298,258 JBrowse link
G Ccnf cyclin F affects response to substance ISO CCNF affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr10:13,253,073...13,279,140 JBrowse link
G Ccng1 cyclin G1 affects response to substance
increases expression
multiple interactions
decreases expression
ISO CCNG1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CCNG1 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of CCNG1 mRNA]
Fluorouracil results in decreased expression of CCNG1 mRNA
CTD PMID:15152939 PMID:16217747 PMID:16557594 PMID:16709241 PMID:17982676 PMID:19272435 PMID:22525470 NCBI chr10:25,176,231...25,182,604 JBrowse link
G Ccng2 cyclin G2 affects response to substance
decreases expression
increases expression
ISO CCNG2 affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CCNG2 mRNA
Fluorouracil results in increased expression of CCNG2 mRNA
CTD PMID:15067352 PMID:16510598 PMID:16557594 PMID:17039268 PMID:18754885 PMID:19272435 NCBI chr14:14,804,321...14,812,819 JBrowse link
G Ccnjl cyclin J-like affects expression ISO Fluorouracil affects the expression of CCNJL mRNA CTD PMID:16584549 NCBI chr10:27,995,682...28,053,428 JBrowse link
G Cd24 CD24 molecule increases expression ISO Fluorouracil results in increased expression of CD24 mRNA CTD PMID:16510598 NCBI chr20:47,074,353...47,079,662 JBrowse link
G Cd274 CD274 molecule increases expression ISO Fluorouracil results in increased expression of CD274 protein CTD PMID:17920123 NCBI chr 1:227,116,627...227,137,379 JBrowse link
G Cd34 CD34 molecule increases expression ISO Fluorouracil results in increased expression of CD34 protein CTD PMID:21296659 NCBI chr13:106,480,074...106,499,462 JBrowse link
G Cd38 CD38 molecule affects expression ISO Fluorouracil affects the expression of CD38 mRNA CTD PMID:16584549 NCBI chr14:67,172,062...67,212,328 JBrowse link
G Cd40 CD40 molecule decreases response to substance
multiple interactions
ISO CD40 results in decreased susceptibility to Fluorouracil
Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]]
CTD PMID:15611226 PMID:20188757 NCBI chr 3:153,790,372...153,805,279 JBrowse link
G Cd40lg CD40 ligand multiple interactions ISO Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] CTD PMID:15611226 NCBI chr  X:135,127,119...135,138,302 JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions EXP [gimeracil co-treated with Fluorouracil] results in decreased expression of CD44 CTD PMID:12364819 NCBI chr 3:89,155,850...89,244,615 JBrowse link
G Cd52 CD52 molecule affects expression
multiple interactions
ISO Fluorouracil affects the expression of CD52 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD52 mRNA]
CTD PMID:15016801 PMID:16584549 NCBI chr 5:146,319,789...146,321,348 JBrowse link
G Cd63 Cd63 molecule decreases expression ISO Fluorouracil results in decreased expression of CD63 CTD PMID:15485462 NCBI chr 7:1,325,108...1,340,447 JBrowse link
G Cd8a CD8a molecule multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD8A mRNA] CTD PMID:15016801 NCBI chr 4:103,365,804...103,370,041 JBrowse link
G Cd8b CD8b molecule affects response to substance
decreases expression
ISO CD8B protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CD8B protein
CTD PMID:15352031 NCBI chr 4:103,312,596...103,328,523 JBrowse link
G Cd9 CD9 molecule decreases expression ISO Fluorouracil results in decreased expression of CD9 protein CTD PMID:21296659 NCBI chr 4:158,256,328...158,289,136 JBrowse link
G Cda cytidine deaminase multiple interactions EXP [CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Fluorouracil CTD PMID:10811482 NCBI chr 5:150,556,615...150,583,231 JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDC20 mRNA] CTD PMID:15016801 NCBI chr 5:131,966,203...131,970,406 JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO Fluorouracil results in decreased expression of CDC25A mRNA CTD PMID:16510598 NCBI chr 8:109,864,356...109,882,734 JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO Fluorouracil results in decreased expression of CDC25B mRNA CTD PMID:16709241 PMID:19272435 NCBI chr 3:118,407,127...118,417,272 JBrowse link
G Cdc25c cell division cycle 25C affects response to substance
decreases expression
ISO CDC25C protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CDC25C mRNA
CTD PMID:15548681 PMID:19272435 NCBI chr18:26,335,156...26,356,199 JBrowse link
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme affects response to substance ISO CDC34 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:10,017,588...10,023,586 JBrowse link
G Cdc40 cell division cycle 40 increases expression ISO Fluorouracil results in increased expression of CDC40 protein CTD PMID:16803524 NCBI chr20:44,273,080...44,325,610 JBrowse link
G Cdc42ep1 CDC42 effector protein 1 affects response to substance ISO CDC42EP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:110,395,287...110,403,203 JBrowse link
G Cdc45 cell division cycle 45 multiple interactions
decreases expression
affects expression
ISO [Leucovorin co-treated with Fluorouracil] results in increased expression of CDC45 mRNA
Fluorouracil results in decreased expression of CDC45 mRNA
Fluorouracil affects the expression of CDC45 mRNA
CTD PMID:15342418 PMID:16557594 PMID:19272435 NCBI chr11:82,185,427...82,210,630 JBrowse link
G Cdc6 cell division cycle 6 affects expression
decreases expression
multiple interactions
increases expression
ISO Fluorouracil affects the expression of CDC6 mRNA
Fluorouracil results in decreased expression of CDC6 mRNA
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDC6 mRNA
Fluorouracil results in increased expression of CDC6 mRNA
CTD PMID:15342418 PMID:16557594 PMID:16709241 PMID:17039268 PMID:19272435 NCBI chr10:83,864,189...83,878,011 JBrowse link
G Cdc73 cell division cycle 73 decreases expression ISO Fluorouracil results in decreased expression of CDC73 mRNA CTD PMID:16510598 NCBI chr13:55,357,226...55,449,690 JBrowse link
G Cdca5 cell division cycle associated 5 increases expression ISO Fluorouracil results in increased expression of CDCA5 mRNA CTD PMID:16709241 NCBI chr 1:203,378,550...203,392,027 JBrowse link
G Cdca7 cell division cycle associated 7 affects expression ISO Fluorouracil affects the expression of CDCA7 mRNA CTD PMID:20421339 NCBI chr 3:57,322,718...57,333,353 JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO Fluorouracil results in decreased expression of CDCA8 mRNA CTD PMID:17374387 NCBI chr 5:137,176,414...137,198,686 JBrowse link
G Cdh1 cadherin 1 affects response to substance
decreases expression
multiple interactions
ISO CDH1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CDH1 protein
resveratrol inhibits the reaction [Fluorouracil results in decreased expression of CDH1 protein]
CTD PMID:15352031 PMID:26310874 NCBI chr19:34,492,371...34,561,775 JBrowse link
G Cdh5 cadherin 5 increases expression
multiple interactions
ISO Fluorouracil results in increased expression of CDH5 protein
Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]
CTD PMID:21296659 PMID:31404653 NCBI chr19:815,415...854,478 JBrowse link
G Cdh6 cadherin 6 decreases expression ISO Fluorouracil results in decreased expression of CDH6 mRNA CTD PMID:24737281 NCBI chr 2:62,079,139...62,225,228 JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase affects expression ISO Fluorouracil affects the expression of CDIPT mRNA CTD PMID:16584549 NCBI chr 1:181,583,098...181,587,409 JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
multiple interactions
increases expression
affects expression
ISO Fluorouracil results in decreased expression of CDK1 mRNA
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDK1 mRNA
Fluorouracil results in increased expression of CDK1 mRNA
Fluorouracil affects the expression of CDK1 mRNA
CTD PMID:15152939 PMID:15205334 PMID:15342418 PMID:16557594 PMID:17039268 PMID:26272751 NCBI chr20:19,266,226...19,281,417 JBrowse link
G Cdk2 cyclin dependent kinase 2 affects response to substance
multiple interactions
increases expression
ISO CDK2 protein affects the susceptibility to Fluorouracil; CDK2 protein modified form affects the susceptibility to Fluorouracil
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDK2 mRNA
Fluorouracil results in increased expression of CDK2 mRNA
CTD PMID:15342418 PMID:15548681 PMID:16557594 PMID:18383818 NCBI chr 7:1,129,878...1,137,431 JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 affects expression ISO Fluorouracil affects the expression of CDK5R1 mRNA CTD PMID:15205334 NCBI chr10:65,484,266...65,485,467 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects response to substance
multiple interactions
increases expression
decreases degradation
decreases expression
decreases response to substance
increases response to substance
ISO CDKN1A affects the susceptibility to Fluorouracil; CDKN1A protein affects the susceptibility to Fluorouracil
Fluorouracil promotes the reaction [Luteolin results in increased expression of CDKN1A protein]; Luteolin promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein]
Fluorouracil results in increased expression of CDKN1A mRNA; Fluorouracil results in increased expression of CDKN1A protein
Fluorouracil results in increased expression of CDKN1A; Fluorouracil results in increased expression of CDKN1A mRNA; Fluorouracil results in increased expression of CDKN1A protein
Fluorouracil results in decreased degradation of CDKN1A protein
Fluorouracil results in decreased expression of CDKN1A protein
[Fluorouracil co-treated with Genistein] results in increased expression of CDKN1A mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in increased expression of CDKN1A protein; [Fluorouracil co-treated with Plant Extracts] results in increased expression of CDKN1A protein; [Leucovorin co-treated with Fluorouracil] results in increased expression of CDKN1A mRNA; CDKN1A protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; CDKN1A protein affects the reaction [Fluorouracil results in decreased expression of UBE2C protein]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of CDKN1A protein]; Fluorouracil promotes the reaction [[TP53 protein binds to SP1 protein] which binds to CDKN1A promoter]; Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CDKN1A mRNA]; Fluorouracil promotes the reaction [temsirolimus results in increased expression of CDKN1A mRNA]; mithramycin A inhibits the reaction [Fluorouracil results in increased expression of CDKN1A protein]; Pravastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein]; Simvastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; temsirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein]
CDKN1A protein results in decreased susceptibility to Fluorouracil
CDKN1A protein results in increased susceptibility to Fluorouracil
CTD PMID:14646558 PMID:14665630 PMID:15016801 PMID:15067352 PMID:15205334 PMID:15331170 PMID:15342418 PMID:15375580 PMID:15489892 PMID:15546879 PMID:15625077 PMID:15754201 PMID:15896711 PMID:16168113 PMID:16434701 PMID:16557594 PMID:16584549 PMID:16686938 PMID:16709241 PMID:16949053 PMID:17039268 PMID:17207318 PMID:17355264 PMID:17699798 PMID:17982676 PMID:18834353 PMID:19098008 PMID:19764996 PMID:24211769 PMID:27129209 PMID:27163855 PMID:31288002 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B affects response to substance
decreases expression
ISO CDKN1B protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CDKN1B mRNA
CTD PMID:17217824 PMID:18930000 NCBI chr 4:167,760,067...167,765,177 JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C affects response to substance
increases expression
ISO CDKN1C affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CDKN1C mRNA
CTD PMID:15067352 PMID:19272435 NCBI chr 1:198,655,394...198,658,097 JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO Fluorouracil results in decreased expression of CDKN2A protein CTD PMID:17982676 NCBI chr 5:103,984,949...103,992,143 JBrowse link
G Cdkn2aip CDKN2A interacting protein affects response to substance ISO CDKN2AIP protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr16:44,536,147...44,546,216 JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO Fluorouracil results in decreased expression of CDKN2C mRNA CTD PMID:16557594 NCBI chr 5:124,411,123...124,416,278 JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDKN3 mRNA] CTD PMID:15016801 NCBI chr15:20,022,522...20,033,948 JBrowse link
G Cdx2 caudal type homeo box 2 decreases expression ISO Fluorouracil results in decreased expression of CDX2 protein
Fluorouracil results in decreased expression of CDX2 mRNA
CTD PMID:21296659 PMID:24737281 NCBI chr12:7,726,798...7,733,142 JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Fluorouracil results in increased expression of CEBPB mRNA CTD PMID:16557594 PMID:16584549 NCBI chr 3:156,398,035...156,399,466 JBrowse link
G Cenpq centromere protein Q affects response to substance
increases expression
ISO CENPQ protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CENPQ mRNA
CTD PMID:15331170 NCBI chr 9:19,957,040...19,972,807 JBrowse link
G Cenpu centromere protein U affects response to substance ISO CENPU protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr16:45,715,821...45,739,038 JBrowse link
G Cenpx centromere protein X affects response to substance ISO CENPX protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:105,991,469...105,994,411 JBrowse link
G Cep55 centrosomal protein 55 decreases expression ISO Fluorouracil results in decreased expression of CEP55 mRNA CTD PMID:17039268 NCBI chr 1:235,832,823...235,848,401 JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist increases expression
decreases expression
ISO Fluorouracil results in increased expression of CER1 mRNA
Fluorouracil results in decreased expression of CER1 mRNA
CTD PMID:24737281 PMID:26272751 NCBI chr 5:97,306,427...97,309,783 JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
increases expression
ISO Fluorouracil promotes the reaction [TP53 protein binds to CES2 intron]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CES2 mRNA] CTD PMID:15205334 PMID:16963839 PMID:17287894 NCBI chr19:32,974,242...32,988,842 JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
affects response to substance
decreases expression
increases expression
ISO [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of CFLAR protein; [Fluorouracil results in decreased expression of CFLAR protein] which results in increased susceptibility to TNFSF10 protein; CFLAR protein alternative form inhibits the reaction [Fluorouracil results in increased activity of TNFSF10 protein]; CFLAR protein inhibits the reaction [Fluorouracil results in increased susceptibility to TNFSF10 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of CFLAR mRNA]
CFLAR protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CFLAR mRNA; Fluorouracil results in decreased expression of CFLAR protein
Fluorouracil results in increased expression of CFLAR mRNA
CTD PMID:15152939 PMID:15548681 PMID:16217747 PMID:16373718 PMID:17045692 PMID:20876774 NCBI chr 9:60,185,338...60,236,173 JBrowse link
G Chek1 checkpoint kinase 1 affects response to substance
decreases expression
increases expression
multiple interactions
ISO CHEK1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CHEK1 mRNA
Fluorouracil results in increased expression of CHEK1 protein
[CHEK1 protein co-treated with TP53 protein] affects the susceptibility to Fluorouracil; Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK1 protein; TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Fluorouracil]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHEK1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of CHEK1 protein]
CTD PMID:15016801 PMID:18698031 PMID:19272435 PMID:21613406 PMID:22194930 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK2 protein CTD PMID:21613406 NCBI chr12:45,788,823...45,821,382 JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Fluorouracil results in increased expression of CHI3L1 mRNA CTD PMID:15205334 NCBI chr13:45,641,802...45,649,787 JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHRNA4 mRNA] CTD PMID:15016801 NCBI chr 3:168,136,246...168,157,839 JBrowse link
G Chst7 carbohydrate sulfotransferase 7 affects response to substance ISO CHST7 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:2,396,260...2,432,828 JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 affects response to substance ISO CIAO1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 3:114,458,671...114,465,928 JBrowse link
G Cideb cell death-inducing DFFA-like effector b increases expression ISO Fluorouracil results in increased expression of CIDEB protein CTD PMID:15585135 PMID:16803524 NCBI chr15:29,252,203...29,256,759 JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects response to substance ISO CITED2 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:12,312,426...12,314,869 JBrowse link
G Ckb creatine kinase B affects response to substance ISO CKB protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:130,729,420...130,732,301 JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO Fluorouracil results in decreased expression of CKS2 mRNA CTD PMID:17374387 PMID:19272435 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clcn3 chloride voltage-gated channel 3 affects response to substance ISO CLCN3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr16:29,127,419...29,200,133 JBrowse link
G Cldn2 claudin 2 decreases expression
multiple interactions
ISO Fluorouracil results in decreased expression of CLDN2 protein
resveratrol inhibits the reaction [Fluorouracil results in decreased expression of CLDN2 protein]
CTD PMID:26310874 NCBI chr  X:103,459,870...103,473,794 JBrowse link
G Cldn4 claudin 4 affects response to substance
decreases expression
ISO CLDN4 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CLDN4 protein
CTD PMID:15352031 NCBI chr12:21,751,638...21,753,436 JBrowse link
G Clec11a C-type lectin domain containing 11A affects response to substance
decreases expression
ISO CLEC11A protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CLEC11A protein
CTD PMID:15352031 NCBI chr 1:94,800,456...94,809,002 JBrowse link
G Clic1 chloride intracellular channel 1 affects response to substance ISO CLIC1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:3,764,867...3,773,711 JBrowse link
G Cltc clathrin heavy chain multiple interactions ISO CLTC protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CLTC mRNA] CTD PMID:15016801 PMID:18927307 NCBI chr10:71,517,661...71,574,591 JBrowse link
G Coch cochlin affects response to substance ISO COCH protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:69,031,139...69,045,124 JBrowse link
G Col12a1 collagen type XII alpha 1 chain decreases expression ISO Fluorouracil results in decreased expression of COL12A1 mRNA CTD PMID:15205334 PMID:16510598 NCBI chr 8:80,547,592...80,665,665 JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO Fluorouracil results in decreased expression of COL1A1 protein CTD PMID:21296659 NCBI chr10:79,883,622...79,900,625 JBrowse link
G Col1a2 collagen type I alpha 2 chain affects expression ISO Fluorouracil affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 4:32,563,938...32,598,868 JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO Fluorouracil results in decreased expression of COL2A1 protein
Fluorouracil results in decreased expression of COL2A1 mRNA
CTD PMID:21296659 PMID:24737281 NCBI chr 7:129,098,489...129,127,620 JBrowse link
G Col3a1 collagen type III alpha 1 chain affects response to substance ISO COL3A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:47,374,611...47,410,547 JBrowse link
G Col4a2 collagen type IV alpha 2 chain affects response to substance
decreases expression
ISO COL4A2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of COL4A2 protein
CTD PMID:15352031 NCBI chr16:78,047,591...78,183,360 JBrowse link
G Col5a2 collagen type V alpha 2 chain affects response to substance ISO COL5A2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:47,448,736...47,598,396 JBrowse link
G Col6a3 collagen type VI alpha 3 chain affects response to substance
multiple interactions
ISO COL6A3 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of COL6A3 mRNA]
CTD PMID:15016801 PMID:16217747 NCBI chr 9:91,361,578...91,439,434 JBrowse link
G Cp ceruloplasmin multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CP mRNA] CTD PMID:15016801 NCBI chr 2:102,439,433...102,498,075 JBrowse link
G Cpa4 carboxypeptidase A4 decreases expression ISO Fluorouracil results in decreased expression of CPA4 mRNA CTD PMID:16510598 NCBI chr 4:59,188,284...59,212,255 JBrowse link
G Cpd carboxypeptidase D affects response to substance
multiple interactions
ISO CPD protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CPD mRNA]
CTD PMID:15016801 PMID:16217747 NCBI chr10:61,623,528...61,687,491 JBrowse link
G Cpe carboxypeptidase E affects response to substance
increases expression
ISO CPE protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CPE protein
CTD PMID:15352031 NCBI chr16:25,030,276...25,142,231 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects response to substance ISO CPT1A protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:200,564,634...200,627,059 JBrowse link
G Cpxm1 carboxypeptidase X (M14 family), member 1 affects expression ISO Fluorouracil affects the expression of CPXM1 mRNA CTD PMID:15205334 NCBI chr 3:117,588,532...117,595,330 JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 affects response to substance
increases expression
ISO CRABP1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CRABP1 protein
CTD PMID:15352031 NCBI chr 8:55,138,363...55,159,360 JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 affects expression ISO Fluorouracil affects the expression of CRABP2 protein CTD PMID:21296659 NCBI chr 2:173,417,004...173,421,352 JBrowse link
G Crhbp corticotropin releasing hormone binding protein affects expression ISO Fluorouracil affects the expression of CRHBP mRNA CTD PMID:15205334 NCBI chr 2:26,692,403...26,704,710 JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 affects response to substance
increases expression
decreases expression
ISO CRIM1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CRIM1 protein
Fluorouracil results in decreased expression of CRIM1 mRNA
CTD PMID:15352031 PMID:16510598 NCBI chr 6:16,695,864...16,870,264 JBrowse link
G Crk CRK proto-oncogene, adaptor protein affects response to substance ISO CRK protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:60,530,469...60,556,703 JBrowse link
G Crygs crystallin, gamma S multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYGS mRNA] CTD PMID:15016801 NCBI chr11:78,207,170...78,212,273 JBrowse link
G Cryl1 crystallin, lambda 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYL1 mRNA] CTD PMID:15016801 NCBI chr15:31,427,011...31,545,997 JBrowse link
G Cryz crystallin zeta decreases expression
multiple interactions
ISO Fluorouracil results in decreased expression of CRYZ mRNA
TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CRYZ mRNA]
CTD PMID:17982676 NCBI chr 2:243,552,037...243,580,369 JBrowse link
G Cse1l chromosome segregation 1 like multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CSE1L mRNA] CTD PMID:15016801 NCBI chr 3:155,641,104...155,678,866 JBrowse link
G Csf1 colony stimulating factor 1 affects response to substance ISO CSF1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:195,377,215...195,396,608 JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Fluorouracil results in increased expression of CSF2 mRNA CTD PMID:18344199 NCBI chr10:38,386,945...38,388,926 JBrowse link
G Csnk1e casein kinase 1, epsilon affects expression ISO Fluorouracil affects the expression of CSNK1E mRNA CTD PMID:16584549 NCBI chr 7:110,983,322...111,006,926 JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects response to substance ISO CSRP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr13:47,158,171...47,179,388 JBrowse link
G Cst7 cystatin F affects response to substance
decreases expression
ISO CST7 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CST7 protein
CTD PMID:15352031 NCBI chr 3:139,396,830...139,405,557 JBrowse link
G Cst8 cystatin 8 affects expression ISO Fluorouracil affects the expression of CST8 mRNA CTD PMID:16584549 NCBI chr 3:136,244,586...136,255,412 JBrowse link
G Cstf3 cleavage stimulation factor subunit 3 affects response to substance
increases expression
ISO CSTF3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CSTF3 mRNA
CTD PMID:15331170 NCBI chr 3:90,966,415...91,037,669 JBrowse link
G Ctbp2 C-terminal binding protein 2 multiple interactions ISO [Fluorouracil co-treated with irinotecan] results in decreased expression of CTBP2 mRNA; CTBP2 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:16391804 PMID:18927307 NCBI chr 1:187,782,064...187,918,115 JBrowse link
G Ctnnd2 catenin delta 2 multiple interactions ISO CTNND2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 2:81,168,976...82,016,495 JBrowse link
G Ctps1 CTP synthase 1 decreases expression ISO Fluorouracil results in decreased expression of CTPS1 mRNA CTD PMID:19219653 NCBI chr 5:134,125,022...134,154,155 JBrowse link
G Ctsb cathepsin B multiple interactions
increases cleavage
ISO CA 074 methyl ester inhibits the reaction [Fluorouracil results in increased cleavage of CTSB protein] CTD PMID:19816940 NCBI chr15:37,389,636...37,410,508 JBrowse link
G Ctsh cathepsin H affects response to substance
increases expression
ISO CTSH protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CTSH protein
CTD PMID:15352031 NCBI chr 8:90,608,941...90,627,824 JBrowse link
G Cttn cortactin decreases expression ISO Fluorouracil results in decreased expression of CTTN protein CTD PMID:15585135 PMID:16803524 NCBI chr 1:199,599,710...199,635,254 JBrowse link
G Cul4a cullin 4A affects response to substance ISO CUL4A protein affects the susceptibility to Fluorouracil CTD PMID:16467204 NCBI chr16:76,385,298...76,422,316 JBrowse link
G Cul4b cullin 4B increases expression ISO Fluorouracil results in increased expression of CUL4B protein CTD PMID:16803524 NCBI chr  X:117,287,481...117,326,688 JBrowse link
G Cul5 cullin 5 increases expression ISO Fluorouracil results in increased expression of CUL5 mRNA CTD PMID:16557594 NCBI chr 8:54,012,963...54,066,751 JBrowse link
G Cutc cutC copper transporter affects response to substance
multiple interactions
ISO CUTC protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CUTC mRNA]
CTD PMID:15016801 PMID:16217747 NCBI chr 1:242,622,276...242,637,048 JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
affects expression
ISO Fluorouracil results in increased expression of CXCL12 mRNA
Fluorouracil affects the expression of CXCL12 mRNA
CTD PMID:16337237 PMID:18344199 NCBI chr 4:150,388,326...150,401,173 JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Bortezomib inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA] CTD PMID:27194111 NCBI chr14:17,181,030...17,183,075 JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein]; Bortezomib inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein]
Fluorouracil results in increased expression of CXCL1 mRNA; Fluorouracil results in increased expression of CXCL1 protein
CTD PMID:27194111 NCBI chr14:17,270,146...17,289,458 JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions ISO CXCR1 gene SNP affects the susceptibility to [oxaliplatin co-treated with Fluorouracil] CTD PMID:16098254 NCBI chr 9:75,768,124...75,771,122 JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects expression ISO Fluorouracil affects the expression of CXCR4 mRNA CTD PMID:16584549 NCBI chr13:40,077,976...40,081,883 JBrowse link
G Cyc1 cytochrome c-1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CYC1 mRNA] CTD PMID:15016801 NCBI chr 7:108,067,106...108,069,483 JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CYCS mRNA CTD PMID:32800223 NCBI chr 4:79,651,894...79,653,994 JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 affects response to substance
multiple interactions
increases expression
ISO CYFIP2 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]
CTD PMID:15016801 PMID:16217747 PMID:17039268 PMID:17982676 NCBI chr10:30,621,318...30,741,113 JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases response to substance ISO CYLD protein results in increased susceptibility to Fluorouracil CTD PMID:21109933 NCBI chr19:18,310,632...18,373,696 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases metabolic processing EXP CYP1A1 protein results in increased metabolism of Fluorouracil CTD PMID:17230597 NCBI chr 8:58,096,021...58,102,130 JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP [CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Fluorouracil CTD PMID:10811482 NCBI chr 1:81,518,387...81,544,999 JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression ISO Fluorouracil affects the expression of CYP2F1 mRNA CTD PMID:16584549 NCBI chr 1:82,416,108...82,429,897 JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 affects expression ISO Fluorouracil affects the expression of CYP2S1 mRNA CTD PMID:20421339 NCBI chr 1:81,309,948...81,325,303 JBrowse link
G Cyp51 cytochrome P450, family 51 affects response to substance ISO CYP51A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:30,036,956...30,055,410 JBrowse link
G Cyth3 cytohesin 3 decreases expression ISO Fluorouracil results in decreased expression of CYTH3 protein CTD PMID:15585135 PMID:16803524 NCBI chr12:10,840,137...10,933,792 JBrowse link
G Dapk1 death associated protein kinase 1 affects expression ISO Fluorouracil affects the expression of DAPK1 mRNA CTD PMID:20421339 NCBI chr17:3,930,223...4,090,991 JBrowse link
G Dars1 aspartyl-tRNA synthetase 1 affects expression ISO Fluorouracil affects the expression of DARS1 mRNA CTD PMID:16584549 NCBI chr13:39,857,936...39,913,055 JBrowse link
G Dbf4 DBF4 zinc finger decreases expression ISO Fluorouracil results in decreased expression of DBF4 mRNA CTD PMID:16510598 NCBI chr 4:25,676,570...25,701,152 JBrowse link
G Dbndd2 dysbindin domain containing 2 affects response to substance ISO DBNDD2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:153,193,213...153,220,651 JBrowse link
G Dcc DCC netrin 1 receptor multiple interactions ISO DCC protein results in increased susceptibility to [Fluorouracil co-treated with Levamisole] CTD PMID:15148649 NCBI chr18:64,868,987...65,972,783 JBrowse link
G Dck deoxycytidine kinase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCK mRNA] CTD PMID:15016801 NCBI chr14:19,305,218...19,326,247 JBrowse link
G Dclk1 doublecortin-like kinase 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCLK1 mRNA] CTD PMID:15016801 NCBI chr 2:139,417,234...139,710,956 JBrowse link
G Dct dopachrome tautomerase affects expression ISO Fluorouracil affects the expression of DCT mRNA CTD PMID:15205334 NCBI chr15:95,062,006...95,100,863 JBrowse link
G Dcx doublecortin decreases expression EXP Fluorouracil results in decreased expression of DCX protein CTD PMID:18702703 NCBI chr  X:107,430,767...107,573,612 JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCXR mRNA] CTD PMID:15016801 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddah2 dimethylarginine dimethylaminohydrolase 2 affects response to substance ISO DDAH2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:3,761,460...3,764,718 JBrowse link
G Ddb2 damage specific DNA binding protein 2 affects response to substance
increases expression
multiple interactions
ISO DDB2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of DDB2 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of DDB2 mRNA]
CTD PMID:15331170 PMID:16584549 PMID:17982676 PMID:22525470 NCBI chr 3:77,185,114...77,207,650 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Fluorouracil results in increased expression of DDIT3 mRNA; Fluorouracil results in increased expression of DDIT3 protein CTD PMID:17355264 PMID:29879413 PMID:32535746 NCBI chr 7:63,115,645...63,121,203 JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Fluorouracil results in increased expression of DDIT4 mRNA CTD PMID:16510598 PMID:16557594 PMID:17039268 NCBI chr20:27,891,989...27,894,088 JBrowse link
G Ddx39b DExD-box helicase 39B increases expression ISO Fluorouracil results in increased expression of DDX39B mRNA CTD PMID:16510598 NCBI chr20:3,547,702...3,585,064 JBrowse link
G Ddx4 DEAD-box helicase 4 increases expression ISO Fluorouracil results in increased expression of DDX4 protein CTD PMID:21296659 NCBI chr 2:44,227,946...44,282,867 JBrowse link
G Dennd2c DENN domain containing 2C affects expression ISO Fluorouracil affects the expression of DENND2C mRNA CTD PMID:20421339 NCBI chr 2:190,622,357...190,690,489 JBrowse link
G Depdc7 DEP domain containing 7 affects expression ISO Fluorouracil affects the expression of DEPDC7 mRNA CTD PMID:20421339 NCBI chr 3:91,099,111...91,121,152 JBrowse link
G Des desmin decreases expression ISO Fluorouracil results in decreased expression of DES protein CTD PMID:21296659 NCBI chr 9:76,850,979...76,858,695 JBrowse link
G Dhfr dihydrofolate reductase affects expression
increases expression
ISO Fluorouracil affects the expression of DHFR mRNA
Fluorouracil results in increased expression of DHFR mRNA
CTD PMID:15109396 PMID:16557594 PMID:21814787 NCBI chr 2:23,585,876...23,611,199 JBrowse link
G Dhx15 DEAH-box helicase 15 increases expression ISO Fluorouracil results in increased expression of DHX15 mRNA CTD PMID:16584549 NCBI chr14:58,787,147...58,825,083 JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases response to substance
increases expression
ISO DIABLO protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of DIABLO mRNA
CTD PMID:16557594 PMID:18031615 NCBI chr12:33,055,784...33,070,400 JBrowse link
G Dicer1 dicer 1 ribonuclease III decreases expression ISO Fluorouracil results in decreased expression of DICER1 mRNA CTD PMID:16510598 NCBI chr 6:123,627,529...123,692,278 JBrowse link
G Dimt1 DIM1 rRNA methyltransferase and ribosome maturation factor multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DIMT1 mRNA] CTD PMID:15016801 NCBI chr 2:38,343,086...38,366,760 JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of DKK1 protein
DKK1 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 PMID:16217747 NCBI chr 1:228,381,521...228,385,202 JBrowse link
G Dkk4 dickkopf WNT signaling pathway inhibitor 4 increases expression ISO Fluorouracil results in increased expression of DKK4 mRNA CTD PMID:16584549 NCBI chr16:69,402,989...69,406,580 JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLC1 mRNA] CTD PMID:15016801 NCBI chr16:55,246,716...55,671,441 JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions ISO DLG1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr11:68,911,883...69,103,230 JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 multiple interactions
increases expression
ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLK1 mRNA]
Fluorouracil results in increased expression of DLK1 mRNA
CTD PMID:15016801 PMID:24737281 NCBI chr 6:128,410,216...128,417,518 JBrowse link
G Dnah2 dynein, axonemal, heavy chain 2 decreases expression ISO Fluorouracil results in decreased expression of DNAH2 mRNA CTD PMID:24737281 NCBI chr10:54,142,648...54,268,901 JBrowse link
G Dner delta/notch-like EGF repeat containing increases expression ISO Fluorouracil results in increased expression of DNER mRNA CTD PMID:16510598 NCBI chr 9:85,586,985...85,902,820 JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO Fluorouracil results in decreased expression of DNMT3B protein CTD PMID:21296659 NCBI chr 3:142,130,592...142,169,124 JBrowse link
G Dpagt1 dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 affects response to substance ISO DPAGT1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:44,664,055...44,671,102 JBrowse link
G Dpy19l1 dpy-19 like C-mannosyltransferase 1 affects response to substance ISO DPY19L1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:22,933,163...23,021,461 JBrowse link
G Dpyd dihydropyrimidine dehydrogenase increases response to substance
decreases expression
increases metabolic processing
decreases response to substance
increases activity
increases expression
affects activity
increases degradation
decreases metabolic processing
affects degradation
affects response to substance
affects metabolic processing
multiple interactions
ISO DPYD gene mutant form results in increased susceptibility to Fluorouracil; DPYD gene polymorphism results in increased susceptibility to Fluorouracil; DPYD mRNA results in increased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of DPYD mRNA
DPYD protein results in increased metabolism of Fluorouracil
DPYD mRNA results in decreased susceptibility to Fluorouracil; DPYD protein results in decreased susceptibility to Fluorouracil
Fluorouracil results in increased activity of DPYD protein
Fluorouracil results in increased expression of DPYD mRNA; Fluorouracil results in increased expression of DPYD protein
Fluorouracil metabolite affects the activity of DPYD protein
DPYD protein results in increased degradation of Fluorouracil
DPYD gene polymorphism results in decreased metabolism of Fluorouracil; DPYD protein mutant form results in decreased metabolism of Fluorouracil
DPYD protein affects the degradation of Fluorouracil
DPYD gene polymorphism affects the susceptibility to Fluorouracil; DPYD gene SNP affects the susceptibility to Fluorouracil; DPYD intron polymorphism affects the susceptibility to Fluorouracil; DPYD mRNA affects the susceptibility to Fluorouracil; DPYD promoter modified form affects the susceptibility to Fluorouracil; DPYD protein affects the susceptibility to Fluorouracil; DPYD protein mutant form affects the susceptibility to Fluorouracil
DPYD affects the metabolism of Fluorouracil; DPYD protein affects the metabolism of Fluorouracil
[Cisplatin co-treated with Fluorouracil] results in decreased expression of DPYD mRNA; [docetaxel co-treated with Fluorouracil] results in decreased expression of DPYD mRNA; [Leucovorin co-treated with Fluorouracil] results in decreased activity of DPYD protein; Camptothecin inhibits the reaction [Fluorouracil results in increased expression of DPYD mRNA]; Cisplatin inhibits the reaction [Fluorouracil results in increased expression of DPYD mRNA]; docetaxel inhibits the reaction [Fluorouracil results in increased activity of DPYD protein]; DPYD protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin]; DPYD results in increased susceptibility to [Fluorouracil co-treated with gimeracil]; Fluorouracil inhibits the reaction [docetaxel results in increased expression of DPYD protein]; gimeracil affects the reaction [DPYD protein results in increased susceptibility to Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in decreased susceptibility to Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in increased degradation of Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in increased metabolism of Fluorouracil]
CTD PMID:3335642 PMID:7503095 PMID:8680084 PMID:9470816 PMID:9816193 PMID:10099659 PMID:11148247 PMID:12044515 PMID:12562666 PMID:12635664 PMID:14689231 PMID:15017333 PMID:15109396 PMID:15239142 PMID:15246190 PMID:15591715 PMID:15655543 PMID:15737843 PMID:15858133 PMID:15865071 PMID:15890242 PMID:15930747 PMID:15949589 PMID:15993511 PMID:16033824 PMID:16115930 PMID:16282729 PMID:16361556 PMID:16525674 PMID:16557585 PMID:16568373 PMID:16646564 PMID:16761622 PMID:17046731 PMID:17064846 PMID:17121937 PMID:17330233 PMID:17377791 PMID:18075467 PMID:18197934 PMID:18225548 PMID:18299612 PMID:18383874 PMID:18443386 PMID:18600527 PMID:18619742 PMID:18846242 PMID:18986760 PMID:19020767 PMID:19093184 PMID:19104657 PMID:19105824 PMID:19219653 NCBI chr 2:206,609,043...207,474,982 JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 affects expression ISO Fluorouracil affects the expression of DPYSL3 mRNA CTD PMID:15205334 NCBI chr18:35,374,429...35,480,462 JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 multiple interactions
increases expression
ISO TP53 protein promotes the reaction [Fluorouracil results in increased expression of DRAM1 mRNA]
Fluorouracil promotes the reaction [Luteolin results in increased expression of DRAM1 protein]; Luteolin promotes the reaction [Fluorouracil results in increased expression of DRAM1 protein]
CTD PMID:17982676 PMID:31288002 NCBI chr 7:22,742,794...22,776,888 JBrowse link
G Drd5 dopamine receptor D5 multiple interactions ISO DRD5 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr14:72,489,347...72,490,774 JBrowse link
G Dst dystonin affects response to substance ISO DST protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:36,135,657...36,529,617 JBrowse link
G Dtwd1 DTW domain containing 1 increases expression ISO Fluorouracil results in increased expression of DTWD1 mRNA CTD PMID:33770205 NCBI chr 3:113,392,402...113,409,322 JBrowse link
G Dtymk deoxythymidylate kinase affects response to substance
multiple interactions
increases expression
ISO DTYMK affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of DTYMK mRNA]
Fluorouracil results in increased expression of DTYMK mRNA
CTD PMID:15016801 PMID:15067352 PMID:15109396 NCBI chr 9:94,315,552...94,324,386 JBrowse link
G Dusp14 dual specificity phosphatase 14 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP14 mRNA] CTD PMID:15016801 NCBI chr10:68,936,483...68,966,347 JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP5 mRNA] CTD PMID:15016801 NCBI chr 1:252,538,408...252,555,320 JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO Fluorouracil results in increased expression of DUSP6 mRNA CTD PMID:16510598 NCBI chr 7:34,092,848...34,097,186 JBrowse link
G Dut deoxyuridine triphosphatase decreases response to substance
decreases expression
ISO DUT protein results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of DUT mRNA
CTD PMID:16557594 PMID:19015155 NCBI chr 3:112,498,864...112,509,994 JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Fluorouracil results in decreased expression of E2F2 CTD PMID:11300326 NCBI chr 5:148,399,193...148,422,595 JBrowse link
G E2f3 E2F transcription factor 3 multiple interactions ISO E2F3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:34,601,756...34,679,139 JBrowse link
G E2f4 E2F transcription factor 4 multiple interactions ISO CDKN1A protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]; TP53 protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]] CTD PMID:27129209 NCBI chr19:33,174,396...33,181,806 JBrowse link
G E2f8 E2F transcription factor 8 affects expression ISO Fluorouracil affects the expression of E2F8 mRNA CTD PMID:16584549 NCBI chr 1:98,565,717...98,584,265 JBrowse link
G Ebp EBP, cholestenol delta-isomerase affects response to substance ISO EBP protein affects the susceptibility to Fluorouracil CTD PMID:15548681 PMID:16217747 NCBI chr  X:14,299,427...14,305,826 JBrowse link
G Echdc3 enoyl CoA hydratase domain containing 3 affects response to substance ISO ECHDC3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:72,070,697...72,093,519 JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression ISO Fluorouracil results in increased expression of ECHS1 mRNA CTD PMID:15152939 NCBI chr 1:194,895,036...194,903,863 JBrowse link
G Ect2 epithelial cell transforming 2 multiple interactions
decreases expression
ISO TP53 protein promotes the reaction [Fluorouracil results in decreased expression of ECT2 mRNA] CTD PMID:17982676 NCBI chr 2:109,975,813...110,037,911 JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 affects response to substance ISO EDIL3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:19,890,396...20,405,028 JBrowse link
G Edn1 endothelin 1 increases expression ISO Fluorouracil results in increased expression of EDN1 mRNA; Fluorouracil results in increased expression of EDN1 protein CTD PMID:1606078 PMID:19098008 NCBI chr17:22,454,924...22,460,812 JBrowse link
G Ednra endothelin receptor type A affects response to substance ISO EDNRA protein affects the susceptibility to Fluorouracil CTD PMID:17032313 NCBI chr19:30,233,540...30,303,727 JBrowse link
G Ednrb endothelin receptor type B decreases expression ISO Fluorouracil results in decreased expression of EDNRB mRNA CTD PMID:24737281 NCBI chr15:80,640,839...80,672,115 JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression
multiple interactions
increases expression
ISO Fluorouracil affects the expression of EEF1A1 protein
TP53 protein inhibits the reaction [Fluorouracil results in increased expression of EEF1A1 mRNA]
CTD PMID:17982676 PMID:21296659 NCBI chr 8:79,341,554...79,344,784 JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression ISO Fluorouracil results in increased expression of EFEMP1 mRNA CTD PMID:24737281 NCBI chr14:102,610,813...102,690,027 JBrowse link
G Efhd1 EF-hand domain family, member D1 affects response to substance ISO EFHD1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:87,938,259...87,984,917 JBrowse link
G Efhd2 EF-hand domain family, member D2 decreases expression ISO Fluorouracil results in decreased expression of EFHD2 mRNA CTD PMID:16510598 NCBI chr 5:154,160,945...154,176,980 JBrowse link
G Efnb2 ephrin B2 affects response to substance
decreases expression
ISO EFNB2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of EFNB2 protein
CTD PMID:15352031 PMID:16217747 NCBI chr16:80,783,389...80,827,420 JBrowse link
G Egfr epidermal growth factor receptor decreases response to substance
decreases expression
increases phosphorylation
affects response to substance
multiple interactions
ISO EGFR gene polymorphism results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of EGFR protein
Fluorouracil results in increased phosphorylation of EGFR protein
EGFR protein affects the susceptibility to Fluorouracil
[Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA; EGFR gene polymorphism affects the susceptibility to [oxaliplatin co-treated with Fluorouracil]; EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil]; EGFR results in increased susceptibility to [Cisplatin co-treated with docetaxel co-treated with Fluorouracil]; Fluorouracil promotes the reaction [Curcumin results in decreased expression of EGFR protein]; Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein]; Fluorouracil results in decreased phosphorylation of and results in decreased activity of EGFR protein; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EGFR protein]
CTD PMID:15737843 PMID:15981280 PMID:16098254 PMID:16836928 PMID:17169374 PMID:17918158 PMID:17982676 PMID:18794807 PMID:19217205 PMID:21947696 NCBI chr14:91,176,931...91,349,722 JBrowse link
G Egr1 early growth response 1 multiple interactions
affects expression
affects localization
increases expression
decreases expression
ISO EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 mRNA]; EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 protein]; Fluorouracil promotes the reaction [EGR1 protein binds to THBS1 promoter]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of EGR1 mRNA]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of EGR1 protein]
Fluorouracil affects the expression of EGR1 mRNA
Fluorouracil affects the localization of EGR1 protein
Fluorouracil results in decreased expression of EGR1 mRNA
CTD PMID:15205334 PMID:16557594 PMID:17039268 PMID:18757417 NCBI chr18:26,463,333...26,465,531 JBrowse link
G Ehd2 EH-domain containing 2 affects response to substance ISO EHD2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:76,639,568...76,658,747 JBrowse link
G Ehf ets homologous factor multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of EHF mRNA] CTD PMID:15016801 NCBI chr 3:89,639,845...89,680,061 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression
ISO Fluorouracil results in increased phosphorylation of EIF2AK3 protein
Fluorouracil results in increased expression of EIF2AK3 mRNA
CTD PMID:29879413 PMID:32535746 NCBI chr 4:102,805,495...102,866,914 JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta decreases expression ISO Fluorouracil results in decreased expression of EIF2B2 protein CTD PMID:15585135 PMID:16803524 NCBI chr 6:104,866,926...104,873,351 JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Fluorouracil results in increased phosphorylation of EIF2S1 protein CTD PMID:29879413 NCBI chr 6:97,672,829...97,697,499 JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H increases expression ISO Fluorouracil results in increased expression of EIF3H protein CTD PMID:15585135 PMID:16803524 NCBI chr 7:83,091,045...83,174,436 JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression
multiple interactions
ISO Fluorouracil results in increased expression of EIF4E mRNA
Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIF4E mRNA]
CTD PMID:15016801 PMID:15611226 PMID:16584549 NCBI chr 2:227,066,519...227,099,261 JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] CTD PMID:15611226 NCBI chr16:64,792,595...64,805,984 JBrowse link
G Eif4h eukaryotic translation initiation factor 4H increases expression ISO Fluorouracil results in increased expression of EIF4H protein CTD PMID:15585135 PMID:16803524 NCBI chr12:22,083,155...22,099,876 JBrowse link
G Eif5 eukaryotic translation initiation factor 5 increases expression ISO Fluorouracil results in increased expression of EIF5 mRNA CTD PMID:17039268
G Eipr1 EARP complex and GARP complex interacting protein 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIPR1 mRNA] CTD PMID:15016801 NCBI chr 6:45,388,451...45,502,089 JBrowse link
G Elmo2 engulfment and cell motility 2 increases expression ISO Fluorouracil results in increased expression of ELMO2 protein CTD PMID:16803524 NCBI chr 3:154,023,661...154,061,259 JBrowse link
G Eln elastin affects expression ISO Fluorouracil affects the expression of ELN mRNA CTD PMID:15205334 NCBI chr12:21,968,544...22,011,929 JBrowse link
G Eloa elongin A affects expression ISO Fluorouracil affects the expression of ELOA mRNA CTD PMID:15205334 NCBI chr 5:148,231,600...148,246,760 JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 affects response to substance ISO ELOVL5 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:78,790,799...78,857,307 JBrowse link
G Emc1 ER membrane protein complex subunit 1 affects expression ISO Fluorouracil affects the expression of EMC1 mRNA CTD PMID:16584549 NCBI chr 5:151,608,557...151,633,888 JBrowse link
G Eml2 EMAP like 2 multiple interactions ISO EML2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 1:78,827,595...78,859,343 JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Fluorouracil results in increased expression of EMP3 mRNA CTD PMID:19272435 NCBI chr 1:96,388,651...96,391,946 JBrowse link
G Enah ENAH, actin regulator affects response to substance ISO ENAH protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr13:93,617,751...93,738,119 JBrowse link
G Endog endonuclease G increases expression
multiple interactions
ISO Fluorouracil results in increased expression of ENDOG protein
casticin inhibits the reaction [Fluorouracil results in increased expression of ENDOG protein]
CTD PMID:32270916 NCBI chr 3:13,449,113...13,451,715 JBrowse link
G Enosf1 enolase superfamily member 1 affects response to substance
decreases response to substance
ISO ENOSF1 protein affects the susceptibility to Fluorouracil
ENOSF1 protein results in decreased susceptibility to Fluorouracil
CTD PMID:15548681 PMID:18357371 NCBI chr 9:113,275,267...113,314,842 JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 decreases expression ISO Fluorouracil results in decreased expression of ENTPD1 mRNA CTD PMID:19219653 NCBI chr 1:239,425,515...239,552,323 JBrowse link
G Eomes eomesodermin decreases expression ISO Fluorouracil results in decreased expression of EOMES protein CTD PMID:21296659 NCBI chr 8:118,181,340...118,189,186 JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Fluorouracil promotes the reaction [EP300 protein binds to UBE2C promoter] CTD PMID:27129209 NCBI chr 7:113,108,476...113,178,529 JBrowse link
G Ep400 E1A binding protein p400 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of EP400 mRNA] CTD PMID:15016801 NCBI chr12:45,891,886...46,002,523 JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO Fluorouracil results in increased expression of EPAS1 mRNA CTD PMID:16557594 NCBI chr 6:7,790,236...7,871,246 JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 affects expression ISO Fluorouracil affects the expression of EPB41L3 mRNA CTD PMID:20421339 NCBI chr 9:109,056,178...109,260,607 JBrowse link
G Epha2 Eph receptor A2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of EPHA2 mRNA] CTD PMID:15016801 NCBI chr 5:153,605,644...153,634,115 JBrowse link
G Ephx1 epoxide hydrolase 1 affects response to substance
increases expression
ISO EPHX1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of EPHX1 mRNA
CTD PMID:15205334 PMID:16217747 NCBI chr13:92,714,315...92,744,124 JBrowse link
G Epo erythropoietin increases response to substance
increases expression
ISO
EXP
EPO protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of EPO protein
CTD PMID:2206997 PMID:16103069 PMID:20020992 NCBI chr12:19,204,258...19,207,948 JBrowse link
G Epor erythropoietin receptor affects response to substance ISO EPOR gene mutant form affects the susceptibility to Fluorouracil CTD PMID:16511603 NCBI chr 8:20,489,678...20,494,257 JBrowse link
G Eppk1 epiplakin 1 increases expression ISO Fluorouracil results in increased expression of EPPK1 mRNA CTD PMID:16510598 NCBI chr 7:107,816,919...107,842,946 JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase decreases expression ISO Fluorouracil results in decreased expression of EPRS1 mRNA CTD PMID:16709241 NCBI chr13:96,901,548...96,971,966 JBrowse link
G Epyc epiphycan affects expression ISO Fluorouracil affects the expression of EPYC mRNA CTD PMID:15205334 NCBI chr 7:32,436,620...32,474,326 JBrowse link
G Eras ES cell expressed Ras decreases expression ISO Fluorouracil results in decreased expression of ERAS protein CTD PMID:21296659 NCBI chr  X:14,573,987...14,578,455 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
affects expression
decreases response to substance
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; [Apigenin co-treated with Fluorouracil] results in decreased expression of ERBB2 protein; [Cisplatin co-treated with Fluorouracil] results in decreased expression of ERBB2 mRNA; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; Curcumin promotes the reaction [Fluorouracil results in decreased phosphorylation of and results in decreased expression of and results in decreased activity of ERBB2 protein]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with pirarubicin co-treated with Fluorouracil]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein
Fluorouracil affects the expression of ERBB2 mRNA
ERBB2 mRNA results in decreased susceptibility to Fluorouracil; ERBB2 results in decreased susceptibility to Fluorouracil
CTD PMID:9816327 PMID:15205334 PMID:15737843 PMID:15940066 PMID:16446318 PMID:16682728 PMID:17918158 PMID:18337622 PMID:19885610 PMID:21712253 NCBI chr10:83,411,197...83,435,078 JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions ISO Fluorouracil promotes the reaction [Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein CTD PMID:17918158 NCBI chr 7:994,549...1,015,876 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions ISO ERBB4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 9:69,523,733...70,596,743 JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit multiple interactions
decreases expression
ISO [Cisplatin co-treated with Fluorouracil] results in decreased expression of ERCC1 mRNA; ERCC1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with Oxaliplatin]; ERCC1 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Oxaliplatin]; ERCC1 gene SNP results in increased susceptibility to [Cisplatin co-treated with Fluorouracil]; ERCC1 mRNA affects the susceptibility to [Cisplatin co-treated with Fluorouracil]
Fluorouracil results in decreased expression of ERCC1 mRNA
CTD PMID:15173087 PMID:15213713 PMID:15737843 PMID:17016597 PMID:17401013 PMID:18448328 PMID:21286668 NCBI chr 1:78,971,310...79,007,963 JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit multiple interactions ISO ERCC2 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]; ERCC2 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin] CTD PMID:15213713 PMID:17401013 NCBI chr 1:79,033,342...79,047,102 JBrowse link
G Ereg epiregulin decreases expression ISO Fluorouracil results in decreased expression of EREG mRNA CTD PMID:16510598 NCBI chr14:17,027,287...17,041,062 JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO Fluorouracil results in increased expression of ERN1 mRNA CTD PMID:32535746 NCBI chr10:91,326,889...91,421,201 JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression ISO Fluorouracil results in decreased expression of ERP29 protein CTD PMID:15585135 PMID:16803524 NCBI chr12:35,089,698...35,095,952 JBrowse link
G Espl1 extra spindle pole bodies like 1, separase affects response to substance ISO ESPL1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 7:133,424,027...133,450,984 JBrowse link
G Etf1 eukaryotic translation termination factor 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETF1 mRNA] CTD PMID:15016801 NCBI chr18:26,502,413...26,530,753 JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects response to substance ISO ETFB protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:93,851,908...93,866,072 JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETS1 mRNA] CTD PMID:15016801 NCBI chr 8:31,045,909...31,168,010 JBrowse link
G Etv2 ETS variant transcription factor 2 multiple interactions ISO Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr 1:85,890,562...85,894,025 JBrowse link
G Exo1 exonuclease 1 affects response to substance ISO HEXO1 protein affects the susceptibility to Fluorouracil CTD PMID:16477629 NCBI chr13:87,809,725...87,834,654 JBrowse link
G Exosc10 exosome component 10 affects response to substance
increases metabolic processing
ISO EXOSC10 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased metabolism of EXOSC10 protein
CTD PMID:18567802 NCBI chr 5:158,995,318...159,018,946 JBrowse link
G F12 coagulation factor XII affects response to substance
decreases expression
ISO F12 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of F12 protein
CTD PMID:15352031 NCBI chr17:9,207,683...9,215,530 JBrowse link
G F2 coagulation factor II decreases expression ISO Fluorouracil results in decreased expression of F2 mRNA CTD PMID:16709241 NCBI chr 3:77,596,196...77,609,486 JBrowse link
G F3 coagulation factor III, tissue factor decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of F3 mRNA
F3 affects the susceptibility to Fluorouracil
CTD PMID:15067352 PMID:16510598 NCBI chr 2:209,827,061...209,838,666 JBrowse link
G F8 coagulation factor VIII multiple interactions ISO F8 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr18:140,848...172,330 JBrowse link
G Fabp7 fatty acid binding protein 7 decreases expression ISO Fluorouracil results in decreased expression of FABP7 mRNA CTD PMID:24737281 NCBI chr20:37,123,193...37,126,725 JBrowse link
G Fads1 fatty acid desaturase 1 affects response to substance ISO FADS1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:206,827,724...206,842,734 JBrowse link
G Fah fumarylacetoacetate hydrolase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAH mRNA] CTD PMID:15016801 NCBI chr 1:138,548,830...138,571,599 JBrowse link
G Fam102a family with sequence similarity 102, member A affects expression ISO Fluorouracil affects the expression of FAM102A mRNA CTD PMID:16584549 NCBI chr 3:15,823,147...15,854,651 JBrowse link
G Fam107b family with sequence similarity 107, member B multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAM107B mRNA] CTD PMID:15016801 NCBI chr17:74,478,608...74,685,027 JBrowse link
G Fam114a1 family with sequence similarity 114, member A1 affects expression ISO Fluorouracil affects the expression of FAM114A1 mRNA CTD PMID:16584549 NCBI chr14:43,275,693...43,346,227 JBrowse link
G Fam171a1 family with sequence similarity 171, member A1 affects response to substance ISO FAM171A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:75,024,582...75,148,348 JBrowse link
G Fam189b family with sequence similarity 189, member B affects response to substance ISO FAM189B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:174,588,984...174,595,281 JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase affects expression ISO Fluorouracil affects the expression of FAM20C mRNA CTD PMID:16584549 NCBI chr12:15,826,864...15,885,423 JBrowse link
G Fam234b family with sequence similarity 234, member B multiple interactions ISO FAM234B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 4:168,048,313...168,124,017 JBrowse link
G Fam76b family with sequence similarity 76, member B decreases expression ISO Fluorouracil results in decreased expression of FAM76B mRNA CTD PMID:16510598 NCBI chr 8:10,689,396...10,711,847 JBrowse link
G Fancc FA complementation group C decreases expression ISO Fluorouracil results in decreased expression of FANCC mRNA CTD PMID:16557594 NCBI chr17:1,680,660...1,822,610 JBrowse link
G Fancg FA complementation group G increases expression
affects response to substance
ISO Fluorouracil results in increased expression of FANCG mRNA
FANCG affects the susceptibility to Fluorouracil; FANCG protein affects the susceptibility to Fluorouracil
CTD PMID:15067352 PMID:15109396 PMID:15548681 NCBI chr 5:57,230,287...57,240,067 JBrowse link
G Fanci FA complementation group I affects response to substance ISO FANCI protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:133,327,264...133,383,661 JBrowse link
G Fars2 phenylalanyl-tRNA synthetase 2, mitochondrial decreases expression ISO Fluorouracil results in decreased expression of FARS2 mRNA CTD PMID:16101138 NCBI chr17:28,319,215...28,746,217 JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
ISO [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of FAS mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of FAS protein; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP8 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP9 protein]; N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]]
Fluorouracil results in increased expression of FAS; Fluorouracil results in increased expression of FAS mRNA; Fluorouracil results in increased expression of FAS protein
CTD PMID:11300326 PMID:14665630 PMID:15016801 PMID:15034078 PMID:15152939 PMID:15161716 PMID:15546879 PMID:15585135 PMID:16557594 PMID:16596200 PMID:16709241 PMID:16957513 PMID:17039268 PMID:17045692 PMID:17056233 PMID:17982676 PMID:18074150 PMID:19015929 PMID:22525470 PMID:33770205 NCBI chr 1:231,798,963...231,832,591 JBrowse link
G Faslg Fas ligand increases response to substance
increases expression
ISO FASL results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of FASL
CTD PMID:11196169 NCBI chr13:74,151,519...74,172,760 JBrowse link
G Fbln1 fibulin 1 affects expression
increases expression
ISO Fluorouracil affects the expression of FBLN1 mRNA
Fluorouracil results in increased expression of FBLN1 mRNA
CTD PMID:15205334 PMID:17039268 NCBI chr 7:116,310,582...116,390,075 JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO Fluorouracil results in decreased expression of FBXO5 mRNA CTD PMID:16557594 PMID:19272435 NCBI chr 1:42,196,068...42,202,437 JBrowse link
G Fdxr ferredoxin reductase multiple interactions
increases expression
ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR protein]
Fluorouracil results in increased expression of FDXR mRNA; Fluorouracil results in increased expression of FDXR mRNA alternative form; Fluorouracil results in increased expression of FDXR protein
CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:16557594 PMID:17982676 PMID:22966307 NCBI chr10:100,507,863...100,516,649 JBrowse link
G Fen1 flap structure-specific endonuclease 1 affects response to substance
increases expression
ISO FEN1 affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of FEN1 mRNA
CTD PMID:15067352 PMID:15109396 NCBI chr 1:206,845,126...206,849,821 JBrowse link
G Fermt2 FERM domain containing kindlin 2 affects response to substance ISO FERMT2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr15:18,682,927...18,751,959 JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 affects response to substance ISO FGD6 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:28,597,609...28,712,908 JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Fluorouracil results in decreased expression of FGF2 mRNA CTD PMID:16510598 NCBI chr 2:120,236,328...120,290,673 JBrowse link
G Fgf4 fibroblast growth factor 4 affects expression ISO Fluorouracil affects the expression of FGF4 protein CTD PMID:21296659 NCBI chr 1:200,023,937...200,027,793 JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO Fluorouracil results in decreased expression of FGF5 protein CTD PMID:21296659 NCBI chr14:11,325,334...11,346,570 JBrowse link
G Fgf7 fibroblast growth factor 7 decreases response to substance
multiple interactions
ISO FGF7 protein results in decreased susceptibility to Fluorouracil; FGF7 results in decreased susceptibility to Fluorouracil
FGFR2 inhibits the reaction [FGF7 results in decreased susceptibility to Fluorouracil]; FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil]
CTD PMID:18575591 NCBI chr 3:113,280,448...113,333,279 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 multiple interactions ISO FGFR2 inhibits the reaction [FGF7 results in decreased susceptibility to Fluorouracil]; FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil] CTD PMID:18575591 NCBI chr 1:184,745,418...184,850,655 JBrowse link
G Fgg fibrinogen gamma chain decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of FGG mRNA
FGG protein affects the susceptibility to Fluorouracil
CTD PMID:16217747 PMID:17039268 NCBI chr 2:168,354,880...168,362,325 JBrowse link
G Fhl2 four and a half LIM domains 2 affects response to substance ISO FHL2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:45,388,979...45,462,530 JBrowse link
G Fhl3 four and a half LIM domains 3 increases expression ISO Fluorouracil results in increased expression of FHL3 mRNA CTD PMID:17039268 NCBI chr 5:136,953,947...136,961,317 JBrowse link
G Filip1l filamin A interacting protein 1-like affects response to substance
increases expression
ISO FILIP1L protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of FILIP1L protein
CTD PMID:15352031 NCBI chr11:42,937,353...43,177,085 JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 affects response to substance ISO FKBP11 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:129,871,870...129,877,760 JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B affects response to substance ISO FKBP1B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:27,832,128...27,850,600 JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of FKBP5 mRNA] CTD PMID:15016801 NCBI chr20:6,457,207...6,575,404 JBrowse link
G Fkbpl FKBP prolyl isomerase like increases expression ISO Fluorouracil results in increased expression of FKBPL mRNA CTD PMID:14503796 NCBI chr20:4,099,845...4,101,315 JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 affects response to substance ISO FLRT2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:114,777,547...114,872,688 JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression
multiple interactions
ISO Fluorouracil results in decreased expression of FLT1 protein
IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of FLT1 protein]
CTD PMID:18157009 NCBI chr12:7,296,899...7,468,626 JBrowse link
G Fmod fibromodulin multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of FMOD mRNA] CTD PMID:15016801 NCBI chr13:45,493,517...45,504,134 JBrowse link
G Fn1 fibronectin 1 decreases expression ISO Fluorouracil results in decreased expression of FN1 protein CTD PMID:21296659 NCBI chr 9:73,196,044...73,264,695 JBrowse link
G Fnbp1 formin binding protein 1 affects response to substance ISO FNBP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:14,316,011...14,386,704 JBrowse link
G Fndc3b fibronectin type III domain containing 3B decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of FNDC3B mRNA
FNDC3B protein affects the susceptibility to Fluorouracil
CTD PMID:16217747 PMID:16510598 NCBI chr 2:110,311,439...110,617,504 JBrowse link
G Folr1 folate receptor alpha decreases expression ISO Fluorouracil results in decreased expression of FOLR1 mRNA CTD PMID:16510598 NCBI chr 1:156,219,460...156,238,436 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
affects expression
ISO Fluorouracil results in increased expression of FOS mRNA
Fluorouracil affects the expression of FOS mRNA
CTD PMID:15205334 PMID:17039268 NCBI chr 6:105,121,170...105,124,036 JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO Fluorouracil results in decreased expression of FOXA2 protein CTD PMID:21296659 NCBI chr 3:135,470,123...135,474,326 JBrowse link
G Foxc1 forkhead box C1 affects expression ISO Fluorouracil affects the expression of FOXC1 mRNA CTD PMID:16584549 NCBI chr17:32,631,379...32,635,361 JBrowse link
G Foxd3 forkhead box D3 decreases expression ISO Fluorouracil results in decreased expression of FOXD3 protein CTD PMID:21296659 NCBI chr 5:114,334,693...114,337,788 JBrowse link
G Foxg1 forkhead box G1 decreases expression ISO Fluorouracil results in decreased expression of FOXG1 mRNA CTD PMID:30518710 NCBI chr 6:66,674,797...66,677,611 JBrowse link
G Foxn3 forkhead box N3 decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of FOXN3 protein
FOXN3 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr 6:118,462,018...118,842,442 JBrowse link
G Foxo3 forkhead box O3 affects response to substance ISO FOXO3 affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr20:45,669,708...45,764,606 JBrowse link
G Fpgs folylpolyglutamate synthase increases response to substance ISO FPGS protein results in increased susceptibility to Fluorouracil CTD PMID:15542523 NCBI chr 3:15,972,800...15,993,592 JBrowse link
G Fut1 fucosyltransferase 1 affects response to substance ISO FUT1 protein affects the susceptibility to Fluorouracil CTD PMID:15649251 NCBI chr 1:96,086,934...96,090,352 JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 increases expression ISO Fluorouracil results in increased expression of FXYD3 mRNA CTD PMID:15152939 NCBI chr 1:86,305,531...86,312,455 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase affects response to substance ISO FYN protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:42,767,733...42,960,903 JBrowse link
G Fzd2 frizzled class receptor 2 affects response to substance ISO FZD2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:87,561,866...87,563,776 JBrowse link
G G0s2 G0/G1switch 2 increases expression
affects response to substance
ISO Fluorouracil results in increased expression of G0S2 protein
G0S2 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr13:104,806,351...104,807,263 JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression ISO Fluorouracil results in increased expression of GABRB3 protein CTD PMID:21296659 NCBI chr 1:108,467,047...108,702,522 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
decreases expression
affects response to substance
increases response to substance
multiple interactions
ISO Fluorouracil results in increased expression of GADD45A mRNA; Fluorouracil results in increased expression of GADD45A protein
Fluorouracil results in decreased expression of GADD45A mRNA
GADD45A protein affects the susceptibility to Fluorouracil
GADD45A protein results in increased susceptibility to Fluorouracil
GADD45A affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in increased expression of GADD45A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of GADD45A mRNA]
CTD PMID:15016801 PMID:15067352 PMID:15205334 PMID:16709241 PMID:16732331 PMID:17982676 PMID:19003803 PMID:19098008 PMID:19272435 PMID:22525470 NCBI chr 4:96,154,789...96,157,091 JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta decreases response to substance
affects response to substance
multiple interactions
ISO GADD45B protein results in decreased susceptibility to Fluorouracil
GADD45B protein affects the susceptibility to Fluorouracil
IFNG protein inhibits the reaction [GADD45B protein results in decreased susceptibility to Fluorouracil]
CTD PMID:16732331 PMID:17711513 NCBI chr 7:8,778,004...8,780,306 JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Fluorouracil results in increased expression of GADD45G mRNA CTD PMID:19272435 NCBI chr17:13,376,842...13,378,587 JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression ISO Fluorouracil results in decreased expression of GAL protein CTD PMID:21296659 NCBI chr 1:200,650,439...200,655,302 JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 affects response to substance ISO GALNT3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:50,742,500...50,779,266 JBrowse link
G Gamt guanidinoacetate N-methyltransferase increases expression
affects response to substance
multiple interactions
ISO Fluorouracil results in increased expression of GAMT protein
GAMT protein affects the susceptibility to Fluorouracil
GAMT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GAMT mRNA]
CTD PMID:15016801 PMID:15352031 PMID:16896004 NCBI chr 7:9,448,590...9,451,778 JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects splicing
decreases expression
ISO Fluorouracil affects the splicing of GAPDH mRNA
Fluorouracil results in decreased expression of GAPDH protein
CTD PMID:17169984 PMID:21296659 NCBI chr 4:157,962,312...157,967,158 JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase increases expression ISO Fluorouracil results in increased expression of GART mRNA CTD PMID:19219653 NCBI chr11:30,864,896...30,891,125 JBrowse link
G Gast gastrin decreases response to substance ISO GAST protein modified form results in decreased susceptibility to Fluorouracil CTD PMID:16618411 NCBI chr10:85,264,832...85,269,393 JBrowse link
G Gata2 GATA binding protein 2 multiple interactions ISO Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr 4:120,654,205...120,667,763 JBrowse link
G Gata4 GATA binding protein 4 affects expression ISO Fluorouracil affects the expression of GATA4 protein CTD PMID:21296659 NCBI chr15:37,459,601...37,531,291 JBrowse link
G Gata6 GATA binding protein 6 affects expression ISO Fluorouracil affects the expression of GATA6 protein CTD PMID:21296659 NCBI chr18:2,188,121...2,219,532 JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects response to substance ISO GCLM protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:210,347,482...210,367,537 JBrowse link
G Gcsh glycine cleavage system protein H multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of GCSH mRNA] CTD PMID:15016801 NCBI chr19:45,036,013...45,046,770 JBrowse link
G Gdf1 growth differentiation factor 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of GDF1 mRNA] CTD PMID:15016801 NCBI chr16:19,097,309...19,112,519 JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions
ISO Fluorouracil results in increased expression of GDF15 mRNA; Fluorouracil results in increased expression of GDF15 protein
TP53 protein affects the reaction [Fluorouracil results in increased expression of GDF15 mRNA]
CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:24737281 NCBI chr16:18,805,312...18,807,893 JBrowse link
G Gdf3 growth differentiation factor 3 affects expression ISO Fluorouracil affects the expression of GDF3 protein CTD PMID:21296659 NCBI chr 4:155,831,572...155,835,953 JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle affects expression ISO Fluorouracil affects the expression of GEM mRNA CTD PMID:15205334 NCBI chr 5:25,214,309...25,225,222 JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO Fluorouracil results in increased expression of GFAP protein CTD PMID:21296659 NCBI chr10:87,852,891...87,861,631 JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO GFRA1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 1:257,315,682...257,552,004 JBrowse link
G Gins1 GINS complex subunit 1 increases response to substance ISO GINS1 gene mutant form results in increased susceptibility to Fluorouracil CTD PMID:18984863 NCBI chr 3:139,724,513...139,745,930 JBrowse link
G Gins2 GINS complex subunit 2 affects expression ISO Fluorouracil affects the expression of GINS2 mRNA CTD PMID:16584549 NCBI chr19:48,626,770...48,639,523 JBrowse link
G Gja1 gap junction protein, alpha 1 affects response to substance ISO GJA1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 PMID:16531325 NCBI chr20:35,756,007...35,768,481 JBrowse link
G Gjc1 gap junction protein, gamma 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of GJC1 mRNA] CTD PMID:15016801 NCBI chr10:87,758,192...87,785,443 JBrowse link
G Gla galactosidase, alpha affects response to substance ISO GLA protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:97,769,227...97,780,646 JBrowse link
G Gli1 GLI family zinc finger 1 decreases expression
multiple interactions
ISO Fluorouracil results in decreased expression of GLI1 mRNA
GLI1 protein inhibits the reaction [Fluorouracil affects the localization of PTCH1 protein]
CTD PMID:18776995 NCBI chr 7:63,156,926...63,169,579 JBrowse link
G Glipr1 GLI pathogenesis-related 1 increases expression ISO Fluorouracil results in increased expression of GLIPR1 mRNA CTD PMID:24737281 NCBI chr 7:47,487,342...47,498,974 JBrowse link
G Gnb2 G protein subunit beta 2 decreases expression ISO Fluorouracil results in decreased expression of GNB2 mRNA CTD PMID:16709241 NCBI chr12:19,159,002...19,164,021 JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of GNE protein
GNE protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr 5:58,267,189...58,307,396 JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta affects expression ISO Fluorouracil affects the expression of GP1BB mRNA CTD PMID:16584549 NCBI chr11:82,378,216...82,379,393 JBrowse link
G Gpr132 G protein-coupled receptor 132 increases expression ISO Fluorouracil results in increased expression of GPR132 mRNA CTD PMID:16584549 NCBI chr 6:131,924,061...131,943,327 JBrowse link
G Gpr137c G protein-coupled receptor 137C affects expression ISO Fluorouracil affects the expression of GPR137C mRNA CTD PMID:16584549 NCBI chr15:18,425,939...18,492,588 JBrowse link
G Gpr35 G protein-coupled receptor 35 affects response to substance
increases expression
ISO GPR35 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of GPR35 mRNA
CTD PMID:15331170 NCBI chr 9:93,526,691...93,539,302 JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO Fluorouracil results in increased expression of GPR87 mRNA CTD PMID:24737281 NCBI chr 2:143,439,741...143,440,901 JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
ISO
EXP
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of GPT protein]
Fluorouracil results in increased activity of GPT protein
CTD PMID:27836789 PMID:29678497 PMID:31129132 NCBI chr 7:108,416,646...108,419,495 JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
multiple interactions
ISO Fluorouracil results in increased expression of GPX1 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of GPX1 mRNA]
CTD PMID:17982676 NCBI chr 8:109,026,905...109,028,031 JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of GPX2 mRNA] CTD PMID:15016801 NCBI chr 6:95,493,589...95,496,877 JBrowse link
G Gramd4 GRAM domain containing 4 increases expression
multiple interactions
ISO Fluorouracil results in increased expression of GRAMD4 mRNA
TP73 protein promotes the reaction [Fluorouracil results in increased expression of GRAMD4 mRNA]
CTD PMID:21127500 NCBI chr 7:117,150,398...117,224,056 JBrowse link
G Grb7 growth factor receptor bound protein 7 increases expression ISO Fluorouracil results in increased expression of GRB7 protein CTD PMID:21296659 NCBI chr10:83,443,387...83,453,057 JBrowse link
G Grhl3 grainyhead-like transcription factor 3 affects expression ISO Fluorouracil affects the expression of GRHL3 mRNA CTD PMID:16584549 NCBI chr 5:147,774,160...147,806,338 JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression ISO Fluorouracil affects the expression of GRINA mRNA CTD PMID:16584549 NCBI chr 7:107,962,194...107,965,368 JBrowse link
G Gspt1 G1 to S phase transition 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of GSPT1 mRNA] CTD PMID:15016801 NCBI chr10:4,362,528...4,397,215 JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO Fluorouracil results in decreased activity of GSR protein CTD PMID:32752303 NCBI chr16:58,482,209...58,525,256 JBrowse link
G Gsta4 glutathione S-transferase alpha 4 affects response to substance ISO GSTA4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:79,066,967...79,084,193 JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of GSTM1 mRNA CTD PMID:32800223 NCBI chr 2:195,649,845...195,655,402 JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
multiple interactions
ISO Fluorouracil results in increased expression of GSTP1 mRNA
[Cisplatin co-treated with Fluorouracil] results in decreased expression of GSTP1 mRNA; GSTP1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]; GSTP1 gene polymorphism results in decreased susceptibility to [Fluorouracil co-treated with Cisplatin]
CTD PMID:15205334 PMID:15213713 PMID:15737843 PMID:16622263 NCBI chr 1:201,337,762...201,340,230 JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression ISO Fluorouracil results in increased expression of GSTT1 protein CTD PMID:15585135 PMID:16803524 NCBI chr20:12,856,613...12,873,586 JBrowse link
G Gtpbp4 GTP binding protein 4 affects response to substance ISO GTPBP4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:61,308,033...61,328,184 JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 decreases expression ISO Fluorouracil results in decreased expression of GUCY1B1 mRNA CTD PMID:19219653 NCBI chr 2:167,348,824...167,398,983 JBrowse link
G H1f0 H1.0 linker histone affects expression ISO Fluorouracil affects the expression of H1F0 mRNA CTD PMID:20421339 NCBI chr 7:110,592,834...110,594,694 JBrowse link
G H2ax H2A.X variant histone affects expression
multiple interactions
increases phosphorylation
ISO Fluorouracil affects the expression of H2AX mRNA
[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased expression of H2AX protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein]; TP53 gene mutant form affects the reaction [benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of H2AX mRNA]
Fluorouracil results in increased phosphorylation of H2AX protein
CTD PMID:15016801 PMID:16584549 PMID:25940438 PMID:26544897 NCBI chr 8:44,671,927...44,673,257 JBrowse link
G H2bc12 H2B clustered histone 12 decreases expression
affects response to substance
increases expression
ISO Fluorouracil results in decreased expression of H2BC12 mRNA
H2BC12 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of H2BC12 protein
CTD PMID:15352031 PMID:16101138 PMID:16217747 NCBI chr17:42,485,746...42,486,126 JBrowse link
G H4c3 H4 clustered histone 3 decreases expression ISO Fluorouracil results in decreased expression of H4C3 mRNA CTD PMID:16510598 PMID:17039268
G H4f3 H1.3 linker histone, cluster member increases expression ISO Fluorouracil results in increased expression of H1-3 protein CTD PMID:15585135 NCBI chr17:41,528,576...41,554,586 JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 affects response to substance ISO HACD1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:77,081,508...77,106,114 JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HAND1 mRNA] CTD PMID:15016801 NCBI chr10:42,006,646...42,009,213 JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 increases expression ISO Fluorouracil results in increased expression of HAND2 mRNA CTD PMID:24737281 NCBI chr16:32,917,826...32,919,880 JBrowse link
G Hapln2 hyaluronan and proteoglycan link protein 2 affects expression ISO Fluorouracil affects the expression of HAPLN2 mRNA CTD PMID:16584549 NCBI chr 2:173,488,909...173,496,824 JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HBA1 mRNA] CTD PMID:15016801 NCBI chr10:15,323,830...15,324,677 JBrowse link
G Hbb hemoglobin subunit beta affects splicing ISO Fluorouracil affects the splicing of HBB mRNA CTD PMID:17169984 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hbe1 hemoglobin subunit epsilon 1 decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of HBE1 protein
HBE1 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr 1:158,282,931...158,458,855 JBrowse link
G Hbz hemoglobin subunit zeta decreases expression ISO Fluorouracil results in decreased expression of HBZ protein CTD PMID:21296659 NCBI chr10:15,343,821...15,345,301 JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC1 protein] CTD PMID:25178657 NCBI chr 5:141,853,992...141,881,057 JBrowse link
G Hdac2 histone deacetylase 2 multiple interactions ISO [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC2 protein] CTD PMID:25178657 NCBI chr20:40,548,250...40,571,609 JBrowse link
G Hdac3 histone deacetylase 3 decreases expression ISO Fluorouracil results in decreased expression of HDAC3 mRNA CTD PMID:19272435 NCBI chr18:29,770,637...29,789,850 JBrowse link
G Hdac4 histone deacetylase 4 decreases expression ISO Fluorouracil results in decreased expression of HDAC4 mRNA CTD PMID:16557594 NCBI chr 9:92,503,467...92,750,164 JBrowse link
G Hdac7 histone deacetylase 7 decreases expression ISO Fluorouracil results in decreased expression of HDAC7 mRNA CTD PMID:26272751 NCBI chr 7:128,923,918...128,962,025 JBrowse link
G Hdac9 histone deacetylase 9 increases expression ISO Fluorouracil results in increased expression of HDAC9 mRNA CTD PMID:24737281 NCBI chr 6:50,762,074...51,624,311 JBrowse link
G Hdgfl3 HDGF like 3 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HDGFL3 mRNA] CTD PMID:15016801 NCBI chr 1:135,822,600...135,876,719 JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HERPUD1 mRNA] CTD PMID:15016801 NCBI chr19:10,598,411...10,609,002 JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases activity ISO Fluorouracil results in increased activity of HES1 protein CTD PMID:19147571 NCBI chr11:70,705,763...70,708,176 JBrowse link
G Hgf hepatocyte growth factor increases expression ISO Fluorouracil results in increased expression of HGF mRNA CTD PMID:24737281 NCBI chr 4:18,673,736...18,745,582 JBrowse link
G Hic2 HIC ZBTB transcriptional repressor 2 affects response to substance ISO HIC2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:83,737,075...83,789,554 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects localization
decreases expression
decreases uptake
affects response to substance
decreases response to substance
multiple interactions
ISO Fluorouracil affects the localization of HIF1A protein
Fluorouracil results in decreased expression of HIF1A protein
HIF1A protein results in decreased uptake of Fluorouracil
HIF1A protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased susceptibility to HIF1A protein; HIF1A results in decreased susceptibility to Fluorouracil
Acetylcysteine inhibits the reaction [Fluorouracil affects the localization of HIF1A protein]; Cyclosporine inhibits the reaction [HIF1A protein results in decreased uptake of Fluorouracil]
CTD PMID:16628086 PMID:17066447 PMID:17219956 PMID:27163855 NCBI chr 6:92,624,059...92,669,262 JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 increases expression ISO Fluorouracil results in increased expression of HINT1 protein CTD PMID:15585135 PMID:16803524 NCBI chr10:38,989,516...38,993,259 JBrowse link
G Hist2h4 histone cluster 2, H4 decreases expression
multiple interactions
ISO Fluorouracil results in decreased expression of H4C2 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of H4C2 mRNA]
CTD PMID:15016801 PMID:17039268 NCBI chr 2:183,831,601...183,831,996 JBrowse link
G Hk2 hexokinase 2 decreases expression
affects response to substance
multiple interactions
ISO Fluorouracil results in decreased expression of HK2 protein
HK2 protein affects the susceptibility to Fluorouracil
HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]
CTD PMID:16595493 PMID:18772588 NCBI chr 4:115,234,509...115,283,530 JBrowse link
G Hm13 histocompatibility minor 13 affects expression ISO Fluorouracil affects the expression of HM13 mRNA CTD PMID:16584549 NCBI chr 3:141,145,769...141,184,703 JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific affects response to substance ISO HMCES protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 4:120,392,812...120,415,616 JBrowse link
G Hmg20b high mobility group 20 B decreases expression ISO Fluorouracil results in decreased expression of HMG20B mRNA CTD PMID:16709241 NCBI chr 7:8,368,934...8,373,650 JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMG1 mRNA] CTD PMID:15016801 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 increases expression ISO Fluorouracil results in increased expression of HMGN5 mRNA CTD PMID:16510598 NCBI chr  X:74,085,871...74,094,488 JBrowse link
G Hmmr hyaluronan-mediated motility receptor multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMMR mRNA] CTD PMID:15016801 NCBI chr10:25,132,933...25,163,029 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
affects expression
ISO
EXP
Fluorouracil results in increased expression of HMOX1
Fluorouracil affects the expression of HMOX1 mRNA
CTD PMID:20722640 PMID:22954530 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 decreases expression
multiple interactions
ISO Fluorouracil results in decreased expression of HNRNPA1 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA1 mRNA]
CTD PMID:15016801 PMID:16101138 NCBI chr 7:134,375,318...134,381,610 JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA2B1 mRNA] CTD PMID:15016801 NCBI chr 4:80,534,659...80,545,297 JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C increases expression ISO Fluorouracil results in increased expression of HNRNPC protein CTD PMID:15585135 PMID:16803524 NCBI chr15:24,779,593...24,809,213 JBrowse link
G Hnrnpf heterogeneous nuclear ribonucleoprotein F multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPF mRNA] CTD PMID:15016801 NCBI chr 4:151,083,262...151,104,464 JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPH1 mRNA] CTD PMID:15016801 NCBI chr10:34,692,868...34,702,849 JBrowse link
G Hnrnpl heterogeneous nuclear ribonucleoprotein L multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPL mRNA] CTD PMID:15016801 NCBI chr 1:84,098,558...84,111,568 JBrowse link
G Hoxa1 homeobox A1 decreases expression ISO Fluorouracil results in decreased expression of HOXA1 mRNA CTD PMID:24737281 NCBI chr 4:81,255,814...81,258,504 JBrowse link
G Hoxb3 homeo box B3 decreases expression ISO Fluorouracil results in decreased expression of HOXB3 mRNA CTD PMID:24737281 NCBI chr10:81,258,739...81,314,134 JBrowse link
G Hoxc11 homeobox C11 affects expression
affects response to substance
ISO Fluorouracil affects the expression of HOXC11 protein
HOXC11 protein affects the susceptibility to Fluorouracil
CTD PMID:15331170 NCBI chr 7:134,091,224...134,094,738 JBrowse link
G Hoxd1 homeo box D1 decreases expression ISO Fluorouracil results in decreased expression of HOXD1 mRNA CTD PMID:24737281 NCBI chr 3:59,665,629...59,667,769 JBrowse link
G Hpx hemopexin multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HPX mRNA] CTD PMID:15016801 NCBI chr 1:159,932,819...159,940,327 JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression ISO Fluorouracil results in increased expression of HRAS mRNA CTD PMID:16557594 NCBI chr 1:196,290,127...196,299,823 JBrowse link
G Hs6st2 heparan sulfate 6-O-sulfotransferase 2 decreases expression ISO Fluorouracil results in decreased expression of HS6ST2 mRNA CTD PMID:16510598 NCBI chr  X:130,966,547...131,261,629 JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects expression ISO Fluorouracil affects the expression of HSD17B2 mRNA CTD PMID:16584549 NCBI chr19:45,753,576...45,825,203 JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of HSPA1B protein
HSPA1B protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr20:3,855,104...3,859,148 JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression
affects response to substance
ISO Fluorouracil results in increased expression of HSPA2 mRNA
HSPA2 protein affects the susceptibility to Fluorouracil
CTD PMID:16101138 PMID:16217747 NCBI chr 6:95,128,504...95,131,281 JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of HSPA4 protein
HSPA4 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr10:37,408,025...37,449,080 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Fluorouracil results in decreased expression of HSPA5 mRNA; Fluorouracil results in decreased expression of HSPA5 protein CTD PMID:29879413 PMID:32535746 NCBI chr 3:18,055,507...18,059,969 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects response to substance ISO HSPA8 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:41,183,397...41,187,260 JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
decreases response to substance
ISO HSPB1 protein affects the susceptibility to [Cisplatin co-treated with Fluorouracil co-treated with Leucovorin]
HSPB1 protein results in decreased susceptibility to Fluorouracil
CTD PMID:18949417 PMID:19088045 NCBI chr12:20,794,014...20,795,675 JBrowse link
G Hspb2 heat shock protein family B (small) member 2 increases phosphorylation
multiple interactions
ISO Fluorouracil results in increased phosphorylation of HSPB2 protein
SB 203580 inhibits the reaction [Fluorouracil results in increased phosphorylation of HSPB2 protein]
CTD PMID:18757417 NCBI chr 8:51,093,267...51,094,864 JBrowse link
G Hspb8 heat shock protein family B (small) member 8 increases expression ISO Fluorouracil results in increased expression of HSPB8 mRNA CTD PMID:16557594 NCBI chr12:40,176,405...40,205,002 JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO Fluorouracil results in increased expression of HSPE1 mRNA CTD PMID:15152939 NCBI chr 9:56,589,912...56,593,000 JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 multiple interactions
increases response to substance
ISO [Fluorouracil co-treated with irinotecan] results in increased expression of HTATIP2 mRNA
HTATIP2 protein results in increased susceptibility to Fluorouracil
CTD PMID:16391804 PMID:16799960 NCBI chr 1:99,473,411...99,488,632 JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 affects expression ISO Fluorouracil affects the expression of HTR7 mRNA CTD PMID:16584549 NCBI chr 1:233,636,442...233,761,063 JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression
affects response to substance
ISO Fluorouracil results in increased expression of HTRA1 protein
HTRA1 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr 1:185,497,815...185,547,380 JBrowse link
G Iapp islet amyloid polypeptide decreases expression ISO Fluorouracil results in decreased expression of IAPP protein CTD PMID:21296659 NCBI chr 4:175,237,013...175,244,373 JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression
multiple interactions
ISO Fluorouracil results in increased expression of ID1 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of ID1 mRNA]
CTD PMID:16557594 NCBI chr 3:141,210,666...141,212,420 JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression
increases expression
multiple interactions
affects response to substance
ISO Fluorouracil results in decreased expression of ID2 protein
Fluorouracil results in increased expression of ID2 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of ID2 mRNA]
ID2 protein affects the susceptibility to Fluorouracil
CTD PMID:15016739 PMID:15352031 PMID:16557594 PMID:25178657 NCBI chr 6:41,740,556...41,742,393 JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO Fluorouracil results in increased expression of ID3 mRNA CTD PMID:15205334 PMID:16557594 NCBI chr 5:148,372,784...148,374,353 JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 affects response to substance ISO IDI1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:61,629,592...61,637,357 JBrowse link
G Ier5 immediate early response 5 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of IER5 mRNA] CTD PMID:15016801 NCBI chr13:67,270,134...67,272,226 JBrowse link
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B multiple interactions ISO [Fluorouracil co-treated with irinotecan] results in increased expression of IFI27L2 mRNA CTD PMID:16391804 NCBI chr 6:122,598,872...122,600,358 JBrowse link
G Ifi35 interferon-induced protein 35 increases expression ISO Fluorouracil results in increased expression of IFI35 mRNA CTD PMID:16101138 NCBI chr10:86,381,023...86,389,279 JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Fluorouracil results in increased expression of IFIT2 mRNA CTD PMID:16101138 NCBI chr 1:232,102,570...232,108,638 JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 decreases expression ISO Fluorouracil results in decreased expression of IFITM1 protein CTD PMID:21296659 NCBI chr 1:196,067,163...196,069,169 JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 increases expression ISO Fluorouracil results in increased expression of IFITM2 protein CTD PMID:21296659 NCBI chr 1:196,051,539...196,052,719 JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 increases expression ISO Fluorouracil results in increased expression of IFNAR1 mRNA; Fluorouracil results in increased expression of IFNAR1 protein CTD PMID:17088986 NCBI chr11:30,725,774...30,752,227 JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 increases expression ISO Fluorouracil results in increased expression of IFNAR2 mRNA; Fluorouracil results in increased expression of IFNAR2 protein CTD PMID:16101138 PMID:17088986 NCBI chr11:30,613,576...30,645,958 JBrowse link
G Ifnb1 interferon beta 1 multiple interactions
increases response to substance
ISO [Fluorouracil co-treated with IFNB1 protein] results in increased activity of CASP3 protein
IFNB1 protein results in increased susceptibility to Fluorouracil
CTD PMID:15937643 PMID:16101138 PMID:18608205 PMID:18695887 NCBI chr 5:103,020,969...103,021,523 JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
increases abundance
ISO [IFNG protein results in increased expression of TYMP protein] which results in increased susceptibility to Fluorouracil; Fluorouracil promotes the reaction [IL18 protein modified form results in increased expression of IFNG protein]; IFNG protein inhibits the reaction [GADD45B protein results in decreased susceptibility to Fluorouracil]
Fluorouracil results in decreased expression of IFNG protein
LCS101 inhibits the reaction [Fluorouracil results in decreased expression of IFNG protein]
IFNG protein results in increased abundance of Fluorouracil
CTD PMID:15162350 PMID:15301717 PMID:15754409 PMID:16568373 PMID:17711513 PMID:23637542 NCBI chr 7:53,903,339...53,907,375 JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP Fluorouracil results in increased expression of IGF1 mRNA CTD PMID:16888818 NCBI chr 7:22,282,895...22,361,972 JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein]; Fluorouracil results in decreased phosphorylation of and results in decreased activity of IGF1R protein CTD PMID:17918158 NCBI chr 1:121,549,839...121,838,545 JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO Fluorouracil results in increased expression of IGFBP2 protein CTD PMID:21296659 NCBI chr 9:74,415,574...74,442,945 JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO IGFBP4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:83,995,253...84,007,272 JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Fluorouracil results in decreased expression of IGFBP5 mRNA CTD PMID:16557594 NCBI chr 9:74,452,371...74,464,953 JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 decreases expression
affects response to substance
ISO Fluorouracil results in decreased expression of IGFBP6 protein
IGFBP6 protein affects the susceptibility to Fluorouracil
CTD PMID:15352031 NCBI chr 7:133,276,309...133,280,944 JBrowse link
G Ihh Indian hedgehog signaling molecule decreases expression ISO Fluorouracil results in decreased expression of IHH mRNA; Fluorouracil results in decreased expression of IHH protein CTD PMID:25190613 NCBI chr 9:76,504,315...76,510,532 JBrowse link
G Ikbip IKBKB interacting protein increases expression
multiple interactions
ISO Fluorouracil results in increased expression of IKBIP mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of IKBIP mRNA]
CTD PMID:17982676 NCBI chr 7:25,579,759...25,598,548 JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL10 protein CTD PMID:31651976 NCBI chr13:42,472,625...42,477,308 JBrowse link
G Il12b interleukin 12B decreases expression ISO Fluorouracil results in decreased expression of IL12B protein CTD PMID:15754409 NCBI chr10:28,888,832...28,903,796 JBrowse link
G Il18 interleukin 18 multiple interactions
affects expression
ISO [Fluorouracil co-treated with irinotecan] results in decreased expression of IL18 mRNA; Fluorouracil promotes the reaction [IL18 protein modified form results in increased expression of IFNG protein]; Fluorouracil results in increased cleavage of and results in increased secretion of IL18 protein
Fluorouracil affects the expression of IL18 mRNA
CTD PMID:15162350 PMID:16391804 PMID:20421339 NCBI chr 8:50,904,630...50,932,887 JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein CTD PMID:31651976 NCBI chr 3:116,526,601...116,537,055 JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion
multiple interactions
ISO
EXP
Fluorouracil results in increased expression of IL1B mRNA; Fluorouracil results in increased expression of IL1B protein
Fluorouracil results in increased secretion of IL1B protein
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1B protein; Hydroxychloroquine inhibits the reaction [Fluorouracil results in increased secretion of IL1B protein]
IL1B promoter polymorphism affects the susceptibility to [Fluorouracil co-treated with Cisplatin]
CTD PMID:16820919 PMID:18523641 PMID:18535404 PMID:19528421 PMID:20844880 PMID:31651976 PMID:32314717 NCBI chr 3:116,577,005...116,583,386 JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO IL1RN protein affects the reaction [Fluorouracil results in increased expression of BAX protein]; IL1RN protein affects the reaction [Fluorouracil results in increased expression of CASP3 protein modified form]; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein] CTD PMID:20844880 NCBI chr 3:7,111,567...7,127,451 JBrowse link
G Il27ra interleukin 27 receptor subunit alpha affects response to substance ISO IL27RA protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:24,109,698...24,121,977 JBrowse link
G Il3 interleukin 3 multiple interactions ISO [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL3 protein CTD PMID:31651976 NCBI chr10:38,405,716...38,408,066 JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
IL6 promoter polymorphism affects the susceptibility to [Fluorouracil co-treated with Cisplatin]
Fluorouracil inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of IL6 protein]
Fluorouracil results in increased expression of IL6 mRNA
CTD PMID:16820919 PMID:18344199 PMID:18523641 PMID:25824412 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Il7 interleukin 7 affects expression ISO Fluorouracil affects the expression of IL7 mRNA CTD PMID:18344199 NCBI chr 2:94,235,219...94,280,075 JBrowse link
G Impa2 inositol monophosphatase 2 increases expression ISO Fluorouracil results in increased expression of IMPA2 mRNA CTD PMID:16510598 NCBI chr18:60,834,206...60,867,575 JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO Fluorouracil results in increased expression of IMPDH2 mRNA CTD PMID:19219653 NCBI chr 8:109,256,705...109,261,365 JBrowse link
G Inka2 inka box actin regulator 2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of INKA2 mRNA] CTD PMID:15016801 NCBI chr 2:193,185,275...193,200,643 JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of INPP5E mRNA] CTD PMID:15016801 NCBI chr 3:9,216,776...9,229,539 JBrowse link
G Ins2 insulin 2 decreases expression ISO Fluorouracil results in decreased expression of INS2 protein CTD PMID:21296659 NCBI chr 1:197,843,277...197,992,522 JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Fluorouracil results in increased expression of INSIG1 mRNA CTD PMID:17039268 NCBI chr 4:7,315,494...7,323,972 JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of IQGAP2 mRNA] CTD PMID:15016801 NCBI chr 2:26,894,836...27,170,270 JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases expression
affects response to substance
ISO Fluorouracil results in increased expression of IRAK1 mRNA
IRAK1 affects the susceptibility to Fluorouracil
CTD PMID:15067352 PMID:15109396 NCBI chr  X:151,768,621...151,778,521 JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression ISO Fluorouracil results in increased expression of IREB2 mRNA CTD PMID:16584549 NCBI chr 8:55,228,080...55,311,613 JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO Fluorouracil results in increased expression of IRF9 mRNA CTD PMID:16101138 PMID:17039268 NCBI chr15:29,095,474...29,101,924 JBrowse link
G Irgm immunity-related GTPase M affects response to substance ISO IRGM1 protein affects the susceptibility to Fluorouracil CTD PMID:18371424 NCBI chr10:33,233,513...33,241,594 JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Fluorouracil results in increased expression of ISG15 mRNA CTD PMID:16101138 PMID:16557594 NCBI chr 5:166,784,148...166,785,435 JBrowse link
G Isl1 ISL LIM homeobox 1 decreases expression ISO Fluorouracil results in decreased expression of ISL1 protein CTD PMID:21296659 NCBI chr 2:48,079,412...48,090,704 JBrowse link
G Itgav integrin subunit alpha V affects response to substance ISO ITGAV protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:68,838,524...68,926,653 JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression ISO Fluorouracil results in decreased expression of ITGB2 CTD PMID:15485462 NCBI chr20:11,061,394...11,097,656 JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO Fluorouracil results in decreased expression of ITGB4 mRNA CTD PMID:15205334 NCBI chr10:101,206,657...101,243,012 JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO TP53 protein affects the react