Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-nitro-1,2-phenylenediamine
go back to main search page
Accession:CHEBI:67116 term browser browse the term
Definition:The primary amino compound that is 1,2-phenylenediamine (o-phenylenediamine) substituted at the 4- (para-) position by a nitro group.
Synonyms:exact_synonym: 4-nitrobenzene-1,2-diamine
 related_synonym: 1,2-Diamino-4-nitrobenzene;   2-Amino-4-nitroaniline;   3,4-Diaminonitrobenzene;   4-Nitro-1,2-benzenediamine;   4-Nitro-1,2-diaminobenzene;   4-Nitro-o-phenylenediamine;   Formula=C6H7N3O2;   InChI=1S/C6H7N3O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,7-8H2;   InChIKey=RAUWPNXIALNKQM-UHFFFAOYSA-N;   SMILES=Nc1ccc(cc1N)[N+]([O-])=O;   p-nitro-o-phenylendiamine;   p-nitro-o-phenylenediamine
 xref: CAS:99-56-9;   KEGG:C19384
 xref_mesh: MESH:C012277
 xref: PMID:1650428;   PMID:2682235;   Patent:KR20080065716;   Reaxys:608106


show annotations for term's descendants           Sort by:
4-nitro-1,2-phenylenediamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of ABCB1B mRNA CTD PMID:17070881 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of ACMSD mRNA CTD PMID:17070881 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of ACSL3 mRNA CTD PMID:17070881 NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Aen apoptosis enhancing nuclease decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of AEN mRNA CTD PMID:17070881 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of AKR1C2 mRNA CTD PMID:26198647 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of AKR7A3 mRNA CTD PMID:17070881 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of ALDH1A1 mRNA CTD PMID:17070881 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of APOA2 mRNA CTD PMID:17070881 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of APOA4 mRNA CTD PMID:17070881 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of APOC3 mRNA CTD PMID:17070881 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Asf1a anti-silencing function 1A histone chaperone increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of ASF1A mRNA CTD PMID:26198647 NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of ATP6V1D mRNA CTD PMID:17070881 NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:97,656,576...97,672,303 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of BAX mRNA CTD PMID:17070881 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of BTG2 mRNA CTD PMID:17070881 NCBI chr13:48,083,931...48,087,690
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G C7 complement C7 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of C7 mRNA CTD PMID:17070881 NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:54,088,116...54,158,535 		JBrowse link
G Cblc Cbl proto-oncogene C decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of CBLC mRNA CTD PMID:17070881 NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:79,439,977...79,456,755 		JBrowse link
G Ccng1 cyclin G1 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of CCNG1 mRNA CTD PMID:17070881 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd276 Cd276 molecule increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of CD276 mRNA CTD PMID:17070881 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of CDKN1A mRNA CTD PMID:17070881 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of CPQ mRNA CTD PMID:17070881 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546 		JBrowse link
G Cryab crystallin, alpha B decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of CRYAB mRNA CTD PMID:17070881 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of CYP2C13 mRNA CTD PMID:17070881 NCBI chr 1:248,706,787...248,787,239
Ensembl chr 1:238,786,765...238,867,191 		JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of CYP4F5 mRNA CTD PMID:17070881 NCBI chr 7:12,194,567...12,209,495
Ensembl chr 7:11,544,082...11,558,978 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of DDAH1 mRNA CTD PMID:17070881 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of EPCAM mRNA CTD PMID:17070881 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of EPHX1 mRNA CTD PMID:17070881 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Fas Fas cell surface death receptor increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of FAS mRNA CTD PMID:17070881 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of FHIT mRNA CTD PMID:17070881 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of GCLC mRNA CTD PMID:26198647 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of GCLM mRNA CTD PMID:26198647 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of GRIA3 mRNA CTD PMID:17070881 NCBI chr  X:125,103,975...125,369,690
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of GSTM1 mRNA CTD PMID:17070881 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of HSD17B6 mRNA CTD PMID:17070881 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of IL2RA mRNA CTD PMID:17070881 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of LIF mRNA CTD PMID:26198647 NCBI chr14:83,354,602...83,364,053
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of MGMT mRNA CTD PMID:17070881 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of NUPR1 mRNA CTD PMID:17070881 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Or2at1 olfactory receptor family 2 subfamily AT member 1 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of OR2AT1 mRNA CTD PMID:17070881 NCBI chr 1:154,089,219...154,090,184
Ensembl chr 1:154,089,219...154,090,184 		JBrowse link
G Orm1 orosomucoid 1 increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of ORM1 protein CTD PMID:20025956 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Pbsn probasin decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of PBSN mRNA CTD PMID:17070881 NCBI chr  X:41,914,346...41,929,591
Ensembl chr  X:41,914,346...41,929,591 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335 		JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of RHOBTB2 mRNA CTD PMID:17070881 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651 		JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of SERPINA7 mRNA CTD PMID:17070881 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040 		JBrowse link
G Slc16a10 solute carrier family 16 member 10 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of SLC16A10 mRNA CTD PMID:17070881 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of SLC7A11 mRNA CTD PMID:26198647 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 decreases expression EXP 1,2-diamino-4-nitrobenzene results in decreased expression of SPINK1 mRNA CTD PMID:17070881 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO 1,2-diamino-4-nitrobenzene results in increased expression of SRXN1 mRNA CTD PMID:26198647 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of SUGCT mRNA CTD PMID:17070881 NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376 		JBrowse link
G Sulf2 sulfatase 2 affects expression EXP 1,2-diamino-4-nitrobenzene affects the expression of SULF2 mRNA CTD PMID:17070881 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of SULT2A1 mRNA CTD PMID:17070881 NCBI chr 1:84,582,011...84,639,001
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression EXP 1,2-diamino-4-nitrobenzene results in increased expression of ZMAT3 mRNA CTD PMID:17070881 NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    chemical entity 20854
      molecular entity 20853
        hydrogen donor 2593
          1,2-phenylenediamine 2593
            4-nitro-1,2-phenylenediamine 54
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    main group molecular entity 20777
                      s-block molecular entity 20573
                        hydrogen molecular entity 20557
                          hydrides 19691
                            inorganic hydride 18601
                              pnictogen hydride 18587
                                nitrogen hydride 18502
                                  azane 18261
                                    ammonia 18260
                                      organic amino compound 18260
                                        polyamine 9125
                                          diamine 9060
                                            primary diamine 5735
                                              phenylenediamine 2686
                                                1,2-phenylenediamine 2593
                                                  4-nitro-1,2-phenylenediamine 54
paths to the root