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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cannabigerolic acid
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Accession:CHEBI:67081 term browser browse the term
Definition:A dihydroxybenzoic acid that is olivetolic acid in which the hydrogen at position 3 is substituted by a geranyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant.
Synonyms:exact_synonym: 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxy-6-pentylbenzoic acid
 related_synonym: (E)-3-(3,7-Dimethyl-2,6-octadienyl)-2,4-dihydroxy-6-pentylbenzoic acid;   Formula=C22H32O4;   InChI=1S/C22H32O4/c1-5-6-7-11-17-14-19(23)18(21(24)20(17)22(25)26)13-12-16(4)10-8-9-15(2)3/h9,12,14,23-24H,5-8,10-11,13H2,1-4H3,(H,25,26)/b16-12+;   InChIKey=SEEZIOZEUUMJME-FOWTUZBSSA-N;   SMILES=CCCCCc1cc(O)c(C\\C=C(/C)CCC=C(C)C)c(O)c1C(O)=O
 xref: CAS:25555-57-1
 xref_mesh: MESH:C100679
 xref: MetaCyc:CPD-7166;   PMID:18283614;   PMID:18303850;   PMID:19704450;   PMID:21532172;   PMID:21726418;   PMID:22495534;   PMID:22766313;   PMID:22802619;   PMID:8663284;   PMID:9607329;   PMID:9862135;   Patent:GB2456183;   Patent:GB2468828;   Patent:US2011021617;   Patent:US2011038958;   Patent:WO2009087351;   Patent:WO2011017798;   Reaxys:2820770
 cyclic_relationship: is_conjugate_acid_of CHEBI:66962

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cannabigerolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma increases expression
decreases expression
ISO cannabigerolic acid results in increased expression of PPARG mRNA
cannabigerolic acid results in decreased expression of PPARG protein
CTD PMID:28853159 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
ISO [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium CTD PMID:31096838 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 affects activity EXP cannabigerolic acid affects the activity of TRPV3 protein CTD PMID:21726418 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            olivetolic acid 12
              cannabigerolic acid 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        aromatic carboxylic acid 11735
                                          benzoic acids 11709
                                            benzoic acid 4280
                                              hydroxybenzoic acid 3691
                                                dihydroxybenzoic acid 64
                                                  cannabigerolic acid 3
paths to the root