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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tocolytic agent
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Accession:CHEBI:66993 term browser browse the term
Definition:Any compound used to suppress premature labour and immature birth by suppressing uterine contractions.
Synonyms:related_synonym: anti-contraction drug;   anti-contraction drugs;   anti-contraction medication;   anti-contraction medications;   labour repressant;   labour repressants;   tocolytic;   tocolytic agents;   tocolytic drug;   tocolytic drugs;   tocolytics
 xref: Wikipedia:Tocolytic



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bambuterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO bambuterol results in decreased activity of ACHE protein CTD PMID:18582854 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Adrb2 adrenoceptor beta 2 increases activity ISO bambuterol results in increased activity of ADRB2 protein CTD PMID:34601065 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Bche butyrylcholinesterase decreases activity ISO bambuterol results in decreased activity of BCHE protein CTD PMID:15652380 PMID:18582854 PMID:18977317 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
fenoterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions ISO [Fenoterol binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; Fenoterol binds to and results in increased activity of ADRB1 protein; Fenoterol inhibits the reaction [cyanopindolol binds to ADRB1 protein] CTD PMID:14730417 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
[Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased abundance of Potassium; [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; Fenoterol binds to and results in increased activity of ADRB2 protein; Fenoterol inhibits the reaction [cyanopindolol binds to ADRB2 protein]; ICI 118551 inhibits the reaction [Fenoterol results in increased activity of ADRB2 protein]
Fenoterol results in increased phosphorylation of ADRB2 protein
[Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine; [ICI 118551 binds to and results in decreased activity of ADRB2 protein] inhibits the reaction [Fenoterol affects the abundance of Norepinephrine]; CGP 20712A inhibits the reaction [[Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine]; Fenoterol binds to and results in increased activity of ADRB2 protein
CTD PMID:7969507 PMID:8102213 PMID:14722251 PMID:14730417 PMID:16474418 More... NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions ISO [Fenoterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; Fenoterol binds to and results in increased activity of ADRB3 protein; Fenoterol inhibits the reaction [cyanopindolol binds to ADRB3 protein] CTD PMID:14730417 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol] CTD PMID:19462961 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Fenoterol results in increased expression of EDNRB mRNA CTD PMID:16340002 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Epo erythropoietin increases expression ISO Fenoterol results in increased expression of EPO protein CTD PMID:9209250 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity EXP Fenoterol results in increased activity of G6PD protein CTD PMID:1978808 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Lep leptin decreases secretion ISO Fenoterol results in decreased secretion of LEP protein CTD PMID:11022189 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:16980553 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:16980553 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol; Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]; CAT protein inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]; Glutathione inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]; Sodium Azide inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]; Sodium Cyanide inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol] CTD PMID:19462961 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO Fenoterol results in increased expression of NR4A3 mRNA CTD PMID:34601065 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Fenoterol results in increased expression of PPARGC1A mRNA CTD PMID:34601065 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ren renin increases activity
increases expression
ISO Fenoterol results in increased activity of REN protein
Fenoterol results in increased expression of REN protein
CTD PMID:2829953 PMID:9209250 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Fenoterol results in increased expression of SIK1 mRNA CTD PMID:34601065 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
magnesium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase multiple interactions EXP Magnesium Sulfate promotes the reaction [Dichlorvos results in decreased activity of BCHE protein] CTD PMID:19504058 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Cat catalase multiple interactions
decreases activity
EXP Magnesium Sulfate promotes the reaction [Vanadates results in decreased activity of CAT protein]
Magnesium Sulfate results in decreased activity of CAT protein
CTD PMID:29117755 PMID:29453945 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity EXP Magnesium Sulfate results in decreased activity of GPX1 protein CTD PMID:29117755 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
EXP Magnesium Sulfate results in decreased activity of GSR protein
[Magnesium Sulfate co-treated with Vanadates] results in decreased activity of GSR protein
CTD PMID:29453945 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Magnesium Sulfate results in decreased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 decreases expression EXP Magnesium Sulfate results in decreased expression of KCNC2 mRNA; Magnesium Sulfate results in decreased expression of KCNC2 protein CTD PMID:18775767 NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968
JBrowse link
G Klk8 kallikrein related-peptidase 8 increases activity ISO Magnesium Sulfate results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646
JBrowse link
G Ren renin increases activity ISO Magnesium Sulfate results in increased activity of REN protein CTD PMID:1874207 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Sod1 superoxide dismutase 1 decreases activity EXP Magnesium Sulfate results in decreased activity of SOD1 protein CTD PMID:29117755 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Trpm5 transient receptor potential cation channel, subfamily M, member 5 affects response to substance ISO TRPM5 protein affects the susceptibility to Magnesium Sulfate CTD PMID:19244541 NCBI chr 1:198,254,956...198,277,824
Ensembl chr 1:198,255,723...198,277,654
JBrowse link
nifedipine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Nifedipine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Nifedipine results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Nifedipine results in increased expression of ABCB1 protein CTD PMID:8632764 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Nifedipine results in increased expression of ABCC2 mRNA CTD PMID:12206135 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases activity
multiple interactions
increases expression
ISO Nifedipine results in increased activity of ABCC3 protein
[Nifedipine results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA
Nifedipine results in increased expression of ABCC3 mRNA
CTD PMID:14570758 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression
multiple interactions
ISO Nifedipine results in decreased expression of AKT1 protein modified form
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin promotes the reaction [[Nifedipine co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein]]; [Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of AKT1 protein; Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein]; Simvastatin promotes the reaction [[Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein]]; Wortmannin inhibits the reaction [Simvastatin promotes the reaction [[Nifedipine co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein]]
CTD PMID:20530298 PMID:20562903 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO Nifedipine results in increased expression of APOA1 CTD PMID:1928808 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 increases expression ISO Nifedipine results in increased expression of APOA2 CTD PMID:1928808 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Avp arginine vasopressin multiple interactions EXP Nifedipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] CTD PMID:14711191 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO
Nifedipine inhibits the reaction [Gentamicins results in increased expression of BAX protein]; Nifedipine inhibits the reaction [Iohexol results in increased expression of BAX protein]
Nifedipine inhibits the reaction [DMD gene mutant form results in increased expression of BAX mRNA]
CTD PMID:19698708 PMID:24349043 PMID:36207783 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
Nifedipine results in decreased expression of BCL2
Nifedipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]; Nifedipine results in increased expression of and affects the localization of BCL2 protein
Nifedipine inhibits the reaction [Gentamicins results in decreased expression of BCL2 protein]; Nifedipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]
CTD PMID:10075388 PMID:10695937 PMID:19698708 PMID:36207783 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP Nifedipine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BDNF protein] CTD PMID:11279263 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C affects response to substance
multiple interactions
ISO CACNA1C protein affects the susceptibility to Nifedipine
Nifedipine inhibits the reaction [[Potassium Chloride co-treated with CACNA1C protein alternative form] results in increased phosphorylation of CREB1 protein]
CTD PMID:18441296 PMID:20128810 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP
ISO
Nifedipine inhibits the reaction [FPL 64176 promotes the reaction [CAMK2A protein binds to DRD3 protein]]
Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein]
CTD PMID:19217379 PMID:28194001 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
Nifedipine inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Phencyclidine results in increased activity of CASP3 protein]]; Nifedipine inhibits the reaction [Iohexol results in increased cleavage of CASP3 protein]; Nifedipine inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein] CTD PMID:24995437 PMID:26923100 PMID:36207783 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Clu clusterin multiple interactions EXP Nifedipine inhibits the reaction [methoxyacetic acid results in increased expression of and results in increased secretion of CLU protein] CTD PMID:14656996 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP
ISO
Nifedipine inhibits the reaction [Nicotine results in increased phosphorylation of CREB1 protein]
Nifedipine inhibits the reaction [Potassium Chloride results in increased phosphorylation of CREB1 protein]
Nifedipine inhibits the reaction [[Potassium Chloride co-treated with CACNA1C protein alternative form] results in increased phosphorylation of CREB1 protein]
CTD PMID:20128810 PMID:21113126 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Csn2 casein beta decreases expression
multiple interactions
ISO Nifedipine results in decreased expression of CSN2 mRNA
Nifedipine promotes the reaction [Cadmium results in decreased expression of CSN2 mRNA]
CTD PMID:21167921 NCBI chr14:20,322,581...20,329,818
Ensembl chr14:20,322,581...20,329,817
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Nifedipine results in decreased activity of CYP1A1 protein CTD PMID:18420780 PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
multiple interactions
ISO
EXP
Nifedipine results in decreased activity of CYP1A2 protein
Nifedipine inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]
CTD PMID:10805063 PMID:18420780 PMID:19858067 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Nifedipine results in decreased activity of CYP1B1 protein CTD PMID:18420780 PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases activity ISO Nifedipine results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity ISO Nifedipine results in decreased activity of CYP2B10 protein CTD PMID:18420780 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP Nifedipine promotes the reaction [Cyclosporine results in increased expression of CYP2C11 protein] CTD PMID:28899749 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Nifedipine results in decreased activity of CYP2C8 protein
Nifedipine results in decreased activity of CYP2C29 protein
CTD PMID:15601807 PMID:18420780
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Nifedipine results in decreased activity of CYP2D6 protein CTD PMID:18420780 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Nifedipine results in decreased activity of CYP2E1 protein CTD PMID:18420780 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases activity ISO Nifedipine results in decreased activity of CYP2J2 protein CTD PMID:30965050 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases oxidation
increases hydroxylation
affects oxidation
increases expression
increases metabolic processing
affects metabolic processing
EXP
ISO
[SOD2 co-treated with CYP3A4] affects the susceptibility to Nifedipine; Nifedipine inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline]
CYP3A4 protein results in increased oxidation of Nifedipine
CYP3A4 protein results in increased hydroxylation of Nifedipine
CYP3A4 protein affects the oxidation of Nifedipine
Nifedipine results in increased expression of CYP3A4 mRNA; Nifedipine results in increased expression of CYP3A4 protein
6',7'-dihydroxybergamottin inhibits the reaction [CYP3A4 protein results in increased oxidation of Nifedipine]; [Nifedipine binds to CYP3A4 promoter] which results in decreased expression of CYP3A4 mRNA; [Nifedipine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA]]; Cimetidine inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Nifedipine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Nifedipine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased oxidation of Nifedipine]; Nifedipine inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; NR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA]; Troleandomycin inhibits the reaction [CYP3A4 protein results in increased oxidation of Nifedipine]; YM 758 inhibits the reaction [CYP3A4 protein results in increased metabolism of Nifedipine]
CYP3A4 protein affects the metabolism of Nifedipine
CTD PMID:2271712 PMID:12851153 PMID:15286053 PMID:15618748 PMID:15634941 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Nifedipine results in increased expression of CYP3A23-3A1 mRNA CTD PMID:16125621 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP Nifedipine inhibits the reaction [Oxygen deficiency results in increased expression of DDIT3 mRNA]; Nifedipine inhibits the reaction [Oxygen deficiency results in increased expression of DDIT3 protein] CTD PMID:22226148 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dmd dystrophin multiple interactions ISO Nifedipine inhibits the reaction [DMD gene mutant form results in increased abundance of Calcium]; Nifedipine inhibits the reaction [DMD gene mutant form results in increased expression of BAX mRNA]; Nifedipine inhibits the reaction [DMD gene mutant form results in increased expression of NOS2 mRNA]; Nifedipine inhibits the reaction [DMD gene mutant form results in increased secretion of Adenosine Triphosphate] CTD PMID:24349043 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP Nifedipine inhibits the reaction [DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]] CTD PMID:11124974 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions EXP Nifedipine inhibits the reaction [FPL 64176 promotes the reaction [CAMK2A protein binds to DRD3 protein]] CTD PMID:19217379 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Edn1 endothelin 1 decreases activity
increases activity
multiple interactions
EXP Nifedipine results in decreased activity of EDN1 protein
Nifedipine results in increased activity of EDN1 protein
Nifedipine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter]
CTD PMID:7528292 PMID:11435416 PMID:12628492 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP Nifedipine inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 mRNA]; Nifedipine inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 protein] CTD PMID:22226148 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions EXP Nifedipine affects the reaction [Haloperidol results in increased phosphorylation of ELK1 protein] CTD PMID:17913375 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO Nifedipine results in increased activity of ESR1 protein CTD PMID:25257666 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance
multiple interactions
ISO Nifedipine affects the susceptibility to FGF2 protein
Nifedipine inhibits the reaction [FGF2 protein results in increased expression of FOS mRNA]
CTD PMID:15141722 PMID:16188231 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf7 fibroblast growth factor 7 increases secretion
increases expression
ISO Nifedipine results in increased secretion of FGF7 protein
Nifedipine results in increased expression of FGF7 mRNA
CTD PMID:11023675 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO
EXP
Nifedipine inhibits the reaction [FGF2 protein results in increased expression of FOS mRNA]
Nifedipine results in decreased expression of FOS protein
[Nifedipine co-treated with omega-Conotoxin GVIA co-treated with omega-Agatoxin IVA] inhibits the reaction [Potassium Chloride affects the expression of FOS mRNA]; Nifedipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Nifedipine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of FOS protein]; Nifedipine inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS protein]; Nifedipine inhibits the reaction [Pentylenetetrazole results in increased expression of FOS protein]
CTD PMID:7534335 PMID:16188231 PMID:17913375 PMID:20211981 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP Nifedipine inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein] CTD PMID:21863293 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions ISO Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein] CTD PMID:28194001 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Nifedipine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP Nifedipine inhibits the reaction [Iohexol results in increased expression of HAVCR1 protein] CTD PMID:36207783 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hdac4 histone deacetylase 4 affects localization EXP Nifedipine affects the localization of HDAC4 protein CTD PMID:20559781 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hgf hepatocyte growth factor increases expression ISO Nifedipine results in increased expression of HGF protein CTD PMID:15071489 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Nifedipine results in increased expression of HMOX1 protein CTD PMID:21525764 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnmt histamine N-methyltransferase decreases activity EXP Nifedipine results in decreased activity of HNMT protein CTD PMID:2408645 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Nifedipine results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Nifedipine inhibits the reaction [Oxygen deficiency results in increased expression of HSPA5 mRNA]; Nifedipine inhibits the reaction [Oxygen deficiency results in increased expression of HSPA5 protein] CTD PMID:22226148 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Igf1 insulin-like growth factor 1 decreases response to substance ISO Nifedipine results in decreased susceptibility to IGF1 protein CTD PMID:16485066 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf2 insulin-like growth factor 2 decreases response to substance ISO Nifedipine results in decreased susceptibility to IGF2 protein CTD PMID:16485066 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Nifedipine results in increased expression of IL1B mRNA CTD PMID:28138970 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Ins1 insulin 1 multiple interactions
decreases expression
EXP Nifedipine inhibits the reaction [Quercetin results in increased secretion of INS1 protein]
Nifedipine results in decreased expression of INS1 protein
CTD PMID:7564366 PMID:23530660 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 multiple interactions EXP [Nifedipine co-treated with omega-Conotoxin GVIA co-treated with omega-Agatoxin IVA] promotes the reaction [Potassium Chloride results in increased expression of KCNA1 mRNA] CTD PMID:20211981 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682
JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 decreases activity ISO Nifedipine results in decreased activity of KCNA3 protein CTD PMID:17638537 NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138
JBrowse link
G Kcnc3 potassium voltage-gated channel subfamily C member 3 multiple interactions EXP [Nifedipine co-treated with omega-Conotoxin GVIA co-treated with omega-Agatoxin IVA] inhibits the reaction [Potassium Chloride results in increased expression of KCNC3 mRNA] CTD PMID:20211981 NCBI chr 1:95,080,960...95,095,165
Ensembl chr 1:95,080,960...95,095,160
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP Nifedipine inhibits the reaction [Iohexol results in increased expression of LCN2 protein] CTD PMID:36207783 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Nifedipine inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK1 protein]
Nifedipine affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]
CTD PMID:15086530 PMID:25045119 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Nifedipine inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK3 protein]
Nifedipine affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]
CTD PMID:15086530 PMID:25045119 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO Nifedipine results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18204791 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Nifedipine results in increased expression of MYC protein CTD PMID:10695937 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myh10 myosin heavy chain 10 decreases expression ISO
EXP
Nifedipine results in decreased expression of MYH10 protein CTD PMID:20530298 NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,394,389...53,525,165
JBrowse link
G Myh11 myosin heavy chain 11 increases expression ISO
EXP
Nifedipine results in increased expression of MYH11 protein CTD PMID:20530298 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
JBrowse link
G Myh7 myosin heavy chain 7 decreases response to substance ISO MYH7 gene mutant form results in decreased susceptibility to Nifedipine CTD PMID:29741611 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Myl9 myosin light chain 9 decreases phosphorylation EXP Nifedipine results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase multiple interactions ISO Nifedipine inhibits the reaction [Glucose results in increased secretion of NAMPT protein] CTD PMID:23536823 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nefl neurofilament light chain multiple interactions EXP Nifedipine inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein] CTD PMID:21863293 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nefm neurofilament medium chain multiple interactions EXP Nifedipine inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFM protein] CTD PMID:21863293 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization ISO Nifedipine affects the localization of NFE2L2 protein CTD PMID:21525764 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:23583884 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Nifedipine inhibits the reaction [NGF protein results in increased uptake of Calcium] CTD PMID:1374475 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Nifedipine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
Nifedipine inhibits the reaction [DMD gene mutant form results in increased expression of NOS2 mRNA]
CTD PMID:11245857 PMID:24349043 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of and results in increased expression of NOS3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin promotes the reaction [[Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of and results in increased expression of NOS3 protein]]; [Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of and results in increased expression of NOS3 protein; Nifedipine inhibits the reaction [[Hydrogen Peroxide results in decreased expression of NOS3 protein] which results in decreased secretion of Nitric Oxide]; Nifedipine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 mRNA]; Nifedipine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 protein]; Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of and results in increased expression of NOS3 protein]; Nifedipine promotes the reaction [Simvastatin inhibits the reaction [[Hydrogen Peroxide results in decreased expression of NOS3 protein] which results in decreased secretion of Nitric Oxide]]; Simvastatin promotes the reaction [[Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of and results in increased expression of NOS3 protein]; Simvastatin promotes the reaction [Nifedipine inhibits the reaction [[Hydrogen Peroxide results in decreased expression of NOS3 protein] which results in decreased secretion of Nitric Oxide]]; Simvastatin promotes the reaction [Nifedipine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 mRNA]]; Simvastatin promotes the reaction [Nifedipine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 protein]]; wortmannin inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of and results in increased expression of NOS3 protein]]; wortmannin inhibits the reaction [Simvastatin promotes the reaction [[Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of and results in increased expression of NOS3 protein]] CTD PMID:20562903 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nppa natriuretic peptide A decreases expression ISO Nifedipine results in decreased expression of NPPA mRNA CTD PMID:20559781 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP [Losartan co-treated with Nifedipine] results in decreased expression of NPPB mRNA CTD PMID:17666919 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
decreases activity
ISO Nifedipine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein]
Nifedipine results in decreased activity of NR1H4 protein
CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [Nifedipine results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; [Nifedipine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA]]; Nifedipine binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA] CTD PMID:14570758 PMID:17041008 PMID:21291553 PMID:25069801 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 decreases expression ISO Nifedipine results in decreased expression of OLR1 mRNA CTD PMID:12072588 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO Nifedipine results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions ISO
EXP
[Nifedipine co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A mRNA]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A mRNA] CTD PMID:18938131 PMID:19162293 PMID:23583884 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Ppif peptidylprolyl isomerase F multiple interactions EXP
ISO
Nifedipine inhibits the reaction [Iohexol results in increased expression of PPIF protein] CTD PMID:36207783 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Prl prolactin multiple interactions EXP Nifedipine inhibits the reaction [bisphenol A results in increased secretion of PRL protein]; Nifedipine inhibits the reaction [Coumestrol results in increased secretion of PRL protein]; Nifedipine inhibits the reaction [Dieldrin results in increased secretion of PRL protein]; Nifedipine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein]; Nifedipine inhibits the reaction [Endosulfan results in increased secretion of PRL protein]; Nifedipine inhibits the reaction [Estradiol results in increased secretion of PRL protein]; Nifedipine inhibits the reaction [nonylphenol results in increased secretion of PRL protein]; Nifedipine inhibits the reaction [o,p'-DDT results in increased secretion of PRL protein] CTD PMID:15811834 PMID:17174995 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
[Nifedipine co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
arachidonyltrifluoromethane promotes the reaction [Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
CTD PMID:18388244 PMID:18938131 PMID:19063610 PMID:23583884 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and affects the localization of RELA protein] CTD PMID:23583884 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ren renin multiple interactions
increases activity
increases expression
ISO [Dexamethasone co-treated with Nifedipine co-treated with Atenolol co-treated with Antihypertensive Agents] results in increased secretion of REN protein; Angiotensin-Converting Enzyme Inhibitors promotes the reaction [Nifedipine results in increased activity of REN protein]; Nifedipine promotes the reaction [Angiotensin-Converting Enzyme Inhibitors results in increased activity of REN protein]
Nifedipine results in increased expression of REN protein
CTD PMID:3142437 PMID:3313686 PMID:3326920 PMID:6184561 PMID:6354932 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G RT1-Bb RT1 class II, locus Bb affects expression ISO Nifedipine affects the expression of HLA-DQB1 mRNA CTD PMID:25811541 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 decreases activity EXP Nifedipine results in decreased activity of SCN5A protein CTD PMID:16331678 PMID:17978865 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Serpinb2 serpin family B member 2 multiple interactions ISO Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINB2 mRNA] CTD PMID:18388244 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions ISO Nifedipine promotes the reaction [SLC10A1 protein results in increased uptake of Indocyanine Green] CTD PMID:32209977 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions EXP Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SLC1A2 protein] CTD PMID:26988466 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Nifedipine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Nifedipine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO Nifedipine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Nifedipine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] CTD PMID:21641380 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc23a2 solute carrier family 23 member 2 multiple interactions ISO Nifedipine inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]; Nifedipine inhibits the reaction [Phosphates results in increased expression of SLC23A2 mRNA] CTD PMID:12788230 NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
affects response to substance
increases expression
EXP
ISO
[SOD2 co-treated with CYP3A4] affects the susceptibility to Nifedipine
SOD2 protein affects the susceptibility to Nifedipine
Nifedipine results in increased expression of SOD2 mRNA; Nifedipine results in increased expression of SOD2 protein
CTD PMID:18327084 PMID:19501153 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO Nifedipine inhibits the reaction [Calcium results in increased expression of SPP1 mRNA]; Nifedipine inhibits the reaction [Phosphates results in increased expression of SPP1 mRNA] CTD PMID:12788230 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP
ISO
Nifedipine inhibits the reaction [Oxygen deficiency results in decreased expression of STAR mRNA]; Nifedipine inhibits the reaction [Oxygen deficiency results in decreased expression of STAR protein]
Nifedipine promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]
CTD PMID:19822634 PMID:22226148 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Losartan co-treated with Nifedipine] results in decreased expression of TGFB1 mRNA CTD PMID:17666919 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein] CTD PMID:23583884 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 decreases expression ISO Nifedipine results in decreased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tp53 tumor protein p53 increases activity ISO Nifedipine results in increased activity of TP53 protein CTD PMID:12082016 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpd52 tumor protein D52 increases expression ISO Nifedipine results in increased expression of TPD52 mRNA CTD PMID:21873647 NCBI chr 2:92,735,365...92,816,079
Ensembl chr 2:92,735,620...92,816,622
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [Nifedipine co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]; Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]
arachidonyltrifluoromethane promotes the reaction [Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]]
CTD PMID:18388244 PMID:18938131 PMID:19063610 PMID:19162293 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin multiple interactions EXP Nifedipine inhibits the reaction [diphenylditelluride results in decreased phosphorylation of VIM protein] CTD PMID:21863293 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
nitroglycerin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 increases expression EXP Nitroglycerin results in increased expression of ACAT1 mRNA CTD PMID:12102619 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Actb actin, beta decreases expression EXP Nitroglycerin results in decreased expression of ACTB mRNA CTD PMID:12102619 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP Nitroglycerin results in decreased expression of ALDH1A1 mRNA CTD PMID:12102619 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions
decreases activity
increases response to substance
decreases expression
affects metabolic processing
affects response to substance
ISO
EXP
[1-aminocyclopropanol analog results in decreased activity of ALDH2 protein] which results in decreased metabolism of Nitroglycerin; [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in decreased metabolism of Nitroglycerin; [Cyanamide results in decreased activity of ALDH2 protein] which results in decreased metabolism of Nitroglycerin; Acetylcysteine inhibits the reaction [Nitroglycerin results in decreased activity of ALDH2 protein]; ALDH2 protein affects the reaction [Nitroglycerin results in decreased abundance of Cyclic GMP]
ALDH2 protein affects the reaction [Ascorbic Acid deficiency results in decreased susceptibility to Nitroglycerin]
ALDH2 protein results in increased susceptibility to Nitroglycerin
Nitroglycerin results in decreased expression of ALDH2 mRNA; Nitroglycerin results in decreased expression of ALDH2 protein
ALDH2 protein affects the metabolism of and results in increased activity of Nitroglycerin; ALDH2 protein affects the reaction [Nitroglycerin results in increased abundance of Reactive Oxygen Species]; Hemin inhibits the reaction [Nitroglycerin results in decreased activity of ALDH2 protein]
ALDH2 protein affects the metabolism of Nitroglycerin
ALDH2 gene polymorphism affects the susceptibility to Nitroglycerin; ALDH2 protein affects the susceptibility to Nitroglycerin; ALDH2 protein polymorphism affects the susceptibility to Nitroglycerin
CTD PMID:15331769 PMID:16440063 PMID:17092343 PMID:17493633 PMID:17541025 More... NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases expression EXP Nitroglycerin results in decreased expression of ALOX15 mRNA CTD PMID:12102619 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression EXP Nitroglycerin results in increased expression of AP2M1 mRNA CTD PMID:12102619 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP Nitroglycerin results in increased expression of APEX1 mRNA CTD PMID:12102619 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression EXP Nitroglycerin results in decreased expression of APOA1 mRNA CTD PMID:12102619 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Arl2 ADP-ribosylation factor like GTPase 2 increases expression EXP Nitroglycerin results in increased expression of ARL2 mRNA CTD PMID:12102619 NCBI chr 1:203,434,129...203,446,156
Ensembl chr 1:203,434,129...203,446,119
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha decreases expression EXP Nitroglycerin results in decreased expression of ATP5F1A mRNA CTD PMID:12102619 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G B2m beta-2 microglobulin affects expression ISO Nitroglycerin affects the expression of B2M protein CTD PMID:8350464 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta decreases expression EXP Nitroglycerin results in decreased expression of BCKDHB mRNA CTD PMID:12102619 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Nitroglycerin results in decreased expression of BCL2 protein CTD PMID:17678976 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G C3 complement C3 increases expression ISO Nitroglycerin results in increased expression of C3 protein alternative form CTD PMID:10884648 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases expression
affects expression
EXP
ISO
Capsaicin inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; Dexamethasone inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; Ergotamine inhibits the reaction [Nitroglycerin results in increased expression of CALCA protein]; Methylene Blue inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; NOS2 protein affects the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; pimagedine inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; Plant Oils inhibits the reaction [Nitroglycerin results in increased expression of CALCA protein]
Nitroglycerin results in increased expression of CALCA mRNA; Nitroglycerin results in increased expression of CALCA protein
Nitroglycerin affects the expression of CALCA protein
CTD PMID:11919648 PMID:14659530 PMID:14729435 PMID:19121572 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calm2 calmodulin 2 increases expression EXP Nitroglycerin results in increased expression of CALM2 mRNA CTD PMID:12102619 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Capn2 calpain 2 decreases expression EXP Nitroglycerin results in decreased expression of CAPN2 mRNA CTD PMID:12102619 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Nitroglycerin results in increased cleavage of and results in increased activity of CASP1 protein CTD PMID:12105852 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 decreases expression
multiple interactions
ISO Nitroglycerin results in decreased expression of CASP3 protein modified form
Nitroglycerin results in increased cleavage of and results in increased activity of CASP3 protein
CTD PMID:12105852 PMID:17322376 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions EXP Nitroglycerin results in increased expression of and results in increased activity of CAT protein CTD PMID:12860443 PMID:14732477 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cd3d CD3 delta subunit of T-cell receptor complex increases expression EXP Nitroglycerin results in increased expression of CD3D mRNA CTD PMID:12102619 NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809
JBrowse link
G Cd5 Cd5 molecule decreases expression EXP Nitroglycerin results in decreased expression of CD5 mRNA CTD PMID:12102619 NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313
JBrowse link
G Cd53 Cd53 molecule decreases expression EXP Nitroglycerin results in decreased expression of CD53 mRNA CTD PMID:12102619 NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone increases expression EXP Nitroglycerin results in increased expression of CDC37 mRNA CTD PMID:12102619 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Nitroglycerin results in increased expression of CDKN1B mRNA CTD PMID:12102619 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Celf2 CUGBP, Elav-like family member 2 increases expression EXP Nitroglycerin results in increased expression of CELF2 mRNA CTD PMID:12102619 NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333
JBrowse link
G Ckb creatine kinase B decreases expression EXP Nitroglycerin results in decreased expression of CKB mRNA CTD PMID:12102619 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Clu clusterin decreases expression EXP Nitroglycerin results in decreased expression of CLU mRNA CTD PMID:12102619 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP Nitroglycerin affects the reaction [glyceryl 2-arachidonate affects the activity of CNR1 protein] CTD PMID:16775503 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cp ceruloplasmin decreases expression EXP Nitroglycerin results in decreased expression of CP mRNA CTD PMID:12102619 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Crip2 cysteine-rich protein 2 decreases expression EXP Nitroglycerin results in decreased expression of CRIP2 mRNA CTD PMID:12102619 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases localization
ISO 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Nitroglycerin results in decreased localization of CTNNB1 protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Nitroglycerin results in increased degradation of and results in decreased activity of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Nitroglycerin results in increased degradation of CTNNB1 protein]; Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]; Nitroglycerin results in decreased phosphorylation of and results in increased nitrosation of and results in increased degradation of and results in decreased activity of CTNNB1 protein; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin results in decreased localization of CTNNB1 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin results in increased degradation of and results in decreased activity of CTNNB1 protein] CTD PMID:17030184 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsd cathepsin D decreases expression EXP Nitroglycerin results in decreased expression of CTSD mRNA CTD PMID:12102619 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
decreases expression
increases expression
decreases response to substance
ISO
EXP
CYBB gene mutant form inhibits the reaction [Nitroglycerin results in decreased susceptibility to Acetylcholine]; Rosuvastatin Calcium inhibits the reaction [Nitroglycerin results in increased expression of CYBB mRNA]
Nitroglycerin results in decreased expression of CYBB mRNA
CYBB gene mutant form results in decreased susceptibility to Nitroglycerin
CTD PMID:16633368 PMID:17493633 PMID:18522491 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression EXP Nitroglycerin results in decreased expression of CYP11B2 mRNA CTD PMID:12102619 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
decreases expression
EXP Vitamin E inhibits the reaction [nitroglycerine decreases Cyp1a2 protein expression in rat heart]
nitroglycerin decreased expression of Cyp1a2 protein in thoracic aorta of rats
RGD PMID:16520233 PMID:12688525 RGD:401900296, RGD:401900656 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 decreases expression EXP Nitroglycerin results in decreased expression of CYP2B15 mRNA CTD PMID:12102619 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Nitroglycerin results in increased expression of CYP2E1 mRNA CTD PMID:12102619 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Defb5 defensin beta 5 decreases expression EXP Nitroglycerin results in decreased expression of DEFB4 mRNA CTD PMID:12102619 NCBI chr16:70,612,985...70,615,389
Ensembl chr16:70,613,146...70,615,467
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression EXP Nitroglycerin results in decreased expression of DHCR7 mRNA CTD PMID:12102619 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 decreases expression EXP Nitroglycerin results in decreased expression of DYNC1I1 mRNA CTD PMID:12102619 NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A decreases expression EXP Nitroglycerin results in decreased expression of DYRK1A mRNA CTD PMID:12102619 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G Edn1 endothelin 1 decreases expression
increases expression
multiple interactions
ISO
EXP
Nitroglycerin results in decreased expression of EDN1 mRNA
Nitroglycerin results in increased expression of EDN1 protein
Nitroglycerin results in decreased expression of EDN1 mRNA; Nitroglycerin results in decreased expression of EDN1 protein
Losartan inhibits the reaction [Nitroglycerin results in increased expression of EDN1 protein]
CTD PMID:11751199 PMID:12206003 PMID:12901495 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Elane elastase, neutrophil expressed increases expression ISO Nitroglycerin results in increased expression of ELANE protein CTD PMID:10884648 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Eln elastin increases expression EXP Nitroglycerin results in increased expression of ELN mRNA CTD PMID:12187120 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Faah fatty acid amide hydrolase increases activity
multiple interactions
EXP Nitroglycerin results in increased activity of FAAH protein
Nitroglycerin promotes the reaction [FAAH protein results in increased chemical synthesis of Arachidonic Acid]; Nitroglycerin promotes the reaction [FAAH protein results in increased degradation of anandamide]
CTD PMID:19515121 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Nitroglycerin results in increased expression of and results in increased localization of FAS protein CTD PMID:12105852 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 increases expression EXP Nitroglycerin results in increased expression of FGFR2 mRNA CTD PMID:12102619 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP Nitroglycerin results in decreased expression of FMO1 mRNA CTD PMID:12102619 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Nitroglycerin results in increased expression of FOS protein
anandamide inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; Ergotamine inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; Plant Oils inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; Pregabalin inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]
CTD PMID:7552308 PMID:10426492 PMID:16897600 PMID:18761334 PMID:19121572 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator decreases expression EXP Nitroglycerin results in decreased expression of GCHFR mRNA CTD PMID:12102619 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
JBrowse link
G Gnb3 G protein subunit beta 3 affects response to substance ISO GNB3 protein affects the susceptibility to Nitroglycerin CTD PMID:14586390 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
JBrowse link
G Gng7 G protein subunit gamma 7 decreases expression EXP Nitroglycerin results in decreased expression of GNG7 mRNA CTD PMID:12102619 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases response to substance ISO GPX1 gene mutant form results in decreased susceptibility to Nitroglycerin CTD PMID:24296279 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression EXP Nitroglycerin results in decreased expression of GRK6 mRNA CTD PMID:12102619 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644
JBrowse link
G Grn granulin precursor decreases expression EXP Nitroglycerin results in decreased expression of GRN mRNA CTD PMID:12102619 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsn gelsolin increases expression EXP Nitroglycerin results in increased expression of GSN mRNA CTD PMID:12187120 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases expression EXP Nitroglycerin results in decreased expression of GSTA2 mRNA CTD PMID:12102619 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 affects metabolic processing EXP GSTA3 protein affects the metabolism of Nitroglycerin CTD PMID:8968379 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gstm2 glutathione S-transferase mu 2 affects metabolic processing EXP GSTM2 protein affects the metabolism of Nitroglycerin CTD PMID:8968379 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gtf3c1 general transcription factor IIIC subunit 1 increases expression EXP Nitroglycerin results in increased expression of GTF3C1 mRNA CTD PMID:12102619 NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 increases expression EXP Nitroglycerin results in increased expression of GUCY1A1 mRNA; Nitroglycerin results in increased expression of GUCY1A1 protein CTD PMID:11331261 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO
EXP
Nitroglycerin results in increased expression of GUCY1B1 protein
Nitroglycerin results in increased expression of GUCY1B1 mRNA; Nitroglycerin results in increased expression of GUCY1B1 protein
CTD PMID:11331261 PMID:11742226 PMID:17541025 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Hbb hemoglobin subunit beta increases expression EXP Nitroglycerin results in increased expression of HBB mRNA CTD PMID:12187120 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hdc histidine decarboxylase decreases expression EXP Nitroglycerin results in decreased expression of HDC mRNA CTD PMID:12102619 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Nitroglycerin results in increased expression of HMOX1 mRNA
[Hemin co-treated with Nitroglycerin] results in increased expression of HMOX1 mRNA; [Hemin co-treated with Nitroglycerin] results in increased expression of HMOX1 protein
CTD PMID:17092343 PMID:17470570 PMID:17541025 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hpn hepsin increases expression EXP Nitroglycerin results in increased expression of HPN mRNA CTD PMID:12102619 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
G Iapp islet amyloid polypeptide increases expression EXP Nitroglycerin results in increased expression of IAPP mRNA CTD PMID:12102619 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression EXP Nitroglycerin results in increased expression of ID2 mRNA CTD PMID:12102619 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 decreases expression EXP Nitroglycerin results in decreased expression of IDO1 protein CTD PMID:28659861 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Il1b interleukin 1 beta increases expression EXP Nitroglycerin results in increased expression of IL1B protein CTD PMID:11701602 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression ISO
EXP
Nitroglycerin results in increased expression of IL6 mRNA; Nitroglycerin results in increased expression of IL6 protein CTD PMID:11701602 PMID:17470570 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jtb jumping translocation breakpoint increases expression EXP Nitroglycerin results in increased expression of JTB mRNA CTD PMID:12102619 NCBI chr 2:175,685,392...175,689,609
Ensembl chr 2:175,684,993...175,690,108
JBrowse link
G Kmo kynurenine 3-monooxygenase decreases expression EXP Nitroglycerin results in decreased expression of KMO protein CTD PMID:28659861 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kng2 kininogen 2 decreases expression EXP Nitroglycerin results in decreased expression of KNG2 mRNA CTD PMID:12102619 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Kynu kynureninase decreases expression EXP Nitroglycerin results in decreased expression of KYNU protein CTD PMID:28659861 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Maob monoamine oxidase B increases expression EXP Nitroglycerin results in increased expression of MAOB mRNA CTD PMID:12102619 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase decreases expression EXP Nitroglycerin results in decreased expression of MECR mRNA CTD PMID:12102619 NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863
JBrowse link
G Mgll monoglyceride lipase multiple interactions
increases activity
EXP Nitroglycerin promotes the reaction [MGLL protein results in increased chemical synthesis of Glycerol]; Nitroglycerin promotes the reaction [MGLL protein results in increased degradation of 2-oleoylglycerol]
Nitroglycerin results in increased activity of MGLL protein
CTD PMID:19515121 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO Nitroglycerin results in increased expression of MMP2 mRNA CTD PMID:12084592 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression ISO Nitroglycerin results in increased expression of MMP7 mRNA CTD PMID:12084592 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases activity
increases expression
ISO Nitroglycerin results in increased activity of MMP9 protein
Nitroglycerin results in increased expression of MMP9 mRNA
CTD PMID:12084592 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase decreases activity EXP Nitroglycerin results in decreased activity of MPO protein CTD PMID:8869312 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression EXP Nitroglycerin results in increased expression of MXI1 mRNA CTD PMID:12102619 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Myo9b myosin IXb decreases expression EXP Nitroglycerin results in decreased expression of MYO9B mRNA CTD PMID:12102619 NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126
JBrowse link
G Ncam1 neural cell adhesion molecule 1 increases expression EXP Nitroglycerin results in increased expression of NCAM1 mRNA CTD PMID:12102619 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 decreases response to substance
multiple interactions
ISO NCF1 gene mutant form results in decreased susceptibility to Nitroglycerin
NCF1 gene mutant form inhibits the reaction [Nitroglycerin results in decreased susceptibility to Acetylcholine]
CTD PMID:18522491 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 decreases expression EXP Nitroglycerin results in decreased expression of NDUFA5 mRNA CTD PMID:12102619 NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:52,995,546...53,005,598
JBrowse link
G Nkx2-1 NK2 homeobox 1 decreases expression EXP Nitroglycerin results in decreased expression of NKX2-1 mRNA CTD PMID:12102619 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
JBrowse link
G Nnat neuronatin increases expression EXP Nitroglycerin results in increased expression of NNAT mRNA CTD PMID:12102619 NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
increases expression
EXP acetylsalicylic acid lysinate inhibits the reaction [Nitroglycerin results in increased expression of NOS1 protein]; Sumatriptan inhibits the reaction [Nitroglycerin results in increased expression of NOS1 protein] CTD PMID:14510930 PMID:15154853 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions
increases expression
ISO
EXP
Nitroglycerin results in decreased expression of NOS2 mRNA
NOS2 protein affects the reaction [Nitroglycerin results in increased expression of CALCA mRNA]
Nitroglycerin results in increased expression of NOS2 mRNA; Nitroglycerin results in increased expression of NOS2 protein
Nitroglycerin results in decreased expression of NOS2 protein
CTD PMID:11701602 PMID:12206003 PMID:14729435 PMID:14732477 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
EXP [Nitroglycerin co-treated with Hemin] results in increased expression of NOS3 mRNA; Nitroglycerin promotes the reaction [[Calcimycin results in increased activity of NOS3 protein] which results in increased abundance of Superoxides]
Nitroglycerin results in increased expression of NOS3 mRNA; Nitroglycerin results in increased expression of NOS3 protein
CTD PMID:10625313 PMID:12860443 PMID:14732477 PMID:17541025 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox1 NADPH oxidase 1 decreases expression EXP Nitroglycerin results in decreased expression of NOX1 mRNA CTD PMID:17493633 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nox4 NADPH oxidase 4 decreases expression EXP Nitroglycerin results in decreased expression of NOX4 mRNA CTD PMID:17493633 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Npy neuropeptide Y increases expression EXP Nitroglycerin results in increased expression of NPY protein CTD PMID:10426492 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase increases expression EXP Nitroglycerin results in increased expression of PAICS mRNA CTD PMID:12102619 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Nitroglycerin results in decreased expression of PARP1 protein alternative form CTD PMID:17322376 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor decreases expression EXP Nitroglycerin results in decreased expression of PCSK1N mRNA CTD PMID:12102619 NCBI chr  X:14,580,036...14,583,478
Ensembl chr  X:14,580,038...14,583,566
JBrowse link
G Pde1a phosphodiesterase 1A increases expression
multiple interactions
EXP Nitroglycerin results in increased expression of PDE1A mRNA; Nitroglycerin results in increased expression of PDE1A protein
PDE1A protein inhibits the reaction [Nitroglycerin results in increased abundance of Cyclic GMP]
CTD PMID:11696475 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874
JBrowse link
G Pde2a phosphodiesterase 2A increases expression EXP Nitroglycerin results in increased expression of PDE2A mRNA CTD PMID:12102619 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pla2g1b phospholipase A2 group IB increases expression EXP Nitroglycerin results in increased expression of PLA2G1B mRNA CTD PMID:12102619 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression EXP Nitroglycerin results in increased expression of PLAUR mRNA CTD PMID:12102619 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Pmp22 peripheral myelin protein 22 decreases expression EXP Nitroglycerin results in decreased expression of PMP22 mRNA CTD PMID:12102619 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Polr1b RNA polymerase I subunit B increases expression EXP Nitroglycerin results in increased expression of POLR1B mRNA CTD PMID:12102619 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression EXP Nitroglycerin results in decreased expression of PPP2CB mRNA CTD PMID:12102619 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 decreases expression EXP Nitroglycerin results in decreased expression of PRKG1 protein CTD PMID:11331261 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Ptgds prostaglandin D2 synthase increases expression EXP Nitroglycerin results in increased expression of PTGDS mRNA CTD PMID:12102619 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R increases expression EXP Nitroglycerin results in increased expression of PTPRR mRNA CTD PMID:12102619 NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603
JBrowse link
G Rab40c Rab40c, member RAS oncogene family increases expression EXP Nitroglycerin results in increased expression of RAB40C mRNA CTD PMID:12187120 NCBI chr10:14,900,926...14,936,153
Ensembl chr10:14,900,929...14,936,557
JBrowse link
G Reg3b regenerating family member 3 beta increases expression EXP Nitroglycerin results in increased expression of REG3B mRNA CTD PMID:12102619 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases localization
multiple interactions
EXP Nitroglycerin results in increased localization of RELA protein
Atorvastatin inhibits the reaction [Nitroglycerin results in increased localization of RELA protein]
CTD PMID:19733216 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ren renin increases activity ISO Nitroglycerin results in increased activity of REN protein CTD PMID:9527094 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rgs8 regulator of G-protein signaling 8 increases expression EXP Nitroglycerin results in increased expression of RGS8 mRNA CTD PMID:12102619 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807
JBrowse link
G Rheb Ras homolog, mTORC1 binding decreases expression EXP Nitroglycerin results in decreased expression of RHEB mRNA CTD PMID:12102619 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Rpl6 ribosomal protein L6 decreases expression EXP Nitroglycerin results in decreased expression of RPL6 mRNA CTD PMID:12102619 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
JBrowse link
G Rps3a ribosomal protein S3a increases expression EXP Nitroglycerin results in increased expression of RPS3A mRNA CTD PMID:12102619 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 decreases expression EXP Nitroglycerin results in decreased expression of SCGB1A1 mRNA CTD PMID:12102619 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
JBrowse link
G Sdc4 syndecan 4 decreases expression EXP Nitroglycerin results in decreased expression of SDC4 mRNA CTD PMID:12102619 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N decreases expression EXP Nitroglycerin results in decreased expression of SERPINA3N mRNA CTD PMID:12102619 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 increases expression EXP Nitroglycerin results in increased expression of SHANK2 mRNA CTD PMID:12102619 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression EXP Nitroglycerin results in increased expression of SLC4A4 mRNA CTD PMID:12102619 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
JBrowse link
G Snn stannin decreases expression EXP Nitroglycerin results in decreased expression of SNN mRNA CTD PMID:12102619 NCBI chr10:4,572,933...4,581,606
Ensembl chr10:4,572,376...4,584,021
JBrowse link
G Snrk SNF related kinase increases expression EXP Nitroglycerin results in increased expression of SNRK mRNA CTD PMID:12102619 NCBI chr 8:121,779,704...121,833,949
Ensembl chr 8:121,793,302...121,832,323
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Nitroglycerin results in increased expression of and results in increased activity of SOD2 protein CTD PMID:12860443 PMID:14732477 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP Nitroglycerin results in increased expression of STAT3 mRNA CTD PMID:12102619 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Syk spleen associated tyrosine kinase increases expression EXP Nitroglycerin results in increased expression of SYK mRNA CTD PMID:12102619 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Syn2 synapsin II increases expression EXP Nitroglycerin results in increased expression of SYN2 mRNA CTD PMID:12102619 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Tac1 tachykinin, precursor 1 affects expression EXP Nitroglycerin affects the expression of TAC1 protein CTD PMID:18197882 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tcf4 transcription factor 4 multiple interactions ISO Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]] CTD PMID:17030184 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases expression EXP Nitroglycerin results in decreased expression of TDO2 protein CTD PMID:28659861 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
G Thy1 Thy-1 cell surface antigen decreases expression EXP Nitroglycerin results in decreased expression of THY1 mRNA CTD PMID:12102619 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Tmpo thymopoietin increases expression EXP Nitroglycerin results in increased expression of TMPO mRNA CTD PMID:12102619 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
ISO
EXP
Nitroglycerin results in decreased expression of TNF protein
Capsaicin inhibits the reaction [Nitroglycerin results in decreased expression of TNF protein]; Methylene Blue inhibits the reaction [Nitroglycerin results in decreased expression of TNF protein]
CTD PMID:10884648 PMID:11744139 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 decreases expression EXP Nitroglycerin results in decreased expression of TNFRSF8 mRNA CTD PMID:12102619 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
G Umod uromodulin increases expression EXP Nitroglycerin results in increased expression of UMOD mRNA CTD PMID:12102619 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions
increases phosphorylation
decreases phosphorylation
ISO
EXP
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Nitroglycerin results in increased phosphorylation of VASP protein]
Nitroglycerin results in decreased phosphorylation of VASP protein
Benomyl inhibits the reaction [Nitroglycerin results in increased phosphorylation of VASP protein]; Hemin inhibits the reaction [Nitroglycerin results in decreased phosphorylation of VASP protein]
CTD PMID:11331261 PMID:14551241 PMID:15331769 PMID:17541025 PMID:17868048 More... NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
G Vtn vitronectin increases expression EXP Nitroglycerin results in increased expression of VTN mRNA CTD PMID:12102619 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta decreases expression EXP Nitroglycerin results in decreased expression of YWHAZ mRNA CTD PMID:12102619 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
sulindac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases expression
multiple interactions
ISO Sulindac results in increased expression of ABCC1 protein
Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC1 protein]
CTD PMID:11820781 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC3 protein] CTD PMID:11820781 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 increases expression EXP Sulindac results in increased expression of ABCD3 mRNA CTD PMID:24136188 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Abhd16a abhydrolase domain containing 16A, phospholipase increases expression EXP Sulindac results in increased expression of ABHD16A mRNA CTD PMID:24136188 NCBI chr20:3,719,089...3,733,952
Ensembl chr20:3,719,091...3,733,927
JBrowse link
G Abi1 abl-interactor 1 decreases expression EXP Sulindac results in decreased expression of ABI1 mRNA CTD PMID:24136188 NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression ISO Sulindac results in increased expression of ACACA mRNA CTD PMID:32535746 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ACAD9 mRNA CTD PMID:20371263 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO
EXP
Sulindac results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acly ATP citrate lyase increases expression ISO Sulindac results in increased expression of ACLY mRNA CTD PMID:32535746 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acp2 acid phosphatase 2, lysosomal increases expression ISO Sulindac results in increased expression of ACP2 mRNA CTD PMID:11906190 NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ACSL1 mRNA CTD PMID:20371263 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Actr10 actin related protein 10 decreases expression EXP Sulindac results in decreased expression of ACTR10 mRNA CTD PMID:24136188 NCBI chr 6:89,446,141...89,472,350
Ensembl chr 6:89,446,093...89,473,047
JBrowse link
G Acy1 aminoacylase 1 increases expression EXP Sulindac results in increased expression of ACY1 mRNA CTD PMID:24136188 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
JBrowse link
G Add1 adducin 1 increases expression EXP Sulindac results in increased expression of ADD1 mRNA CTD PMID:24136188 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ADHFE1 mRNA CTD PMID:20371263 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ADIPOR2 mRNA CTD PMID:20371263 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adss2 adenylosuccinate synthase 2 increases expression EXP Sulindac results in increased expression of ADSS2 mRNA CTD PMID:24136188 NCBI chr13:89,769,240...89,799,577
Ensembl chr13:89,769,244...89,799,604
JBrowse link
G Agfg2 ArfGAP with FG repeats 2 increases expression EXP Sulindac results in increased expression of CCZ1B mRNA CTD PMID:24136188 NCBI chr12:19,012,228...19,048,433
Ensembl chr12:19,012,258...19,048,421
JBrowse link
G Ahr aryl hydrocarbon receptor increases localization
multiple interactions
ISO
EXP
Sulindac results in increased localization of AHR protein
Sulindac binds to and results in increased activity of AHR protein
CTD PMID:16531450 PMID:17985343 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aif1l allograft inflammatory factor 1-like decreases expression ISO Sulindac results in decreased expression of AIF1L mRNA CTD PMID:11906190 NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO Sulindac affects the localization of AIFM1 protein CTD PMID:15946692 PMID:17136320 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 increases expression ISO Sulindac results in increased expression of AIFM2 mRNA CTD PMID:11906190 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236
JBrowse link
G Akap1 A-kinase anchoring protein 1 increases expression EXP Sulindac results in increased expression of AKAP1 mRNA CTD PMID:24136188 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
JBrowse link
G Akap9 A-kinase anchoring protein 9 decreases expression EXP Sulindac results in decreased expression of AKAP9 mRNA CTD PMID:24136188 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 multiple interactions ISO Sulindac analog binds to and results in decreased activity of AKR1B1 protein; Sulindac binds to and results in decreased activity of AKR1B1 protein CTD PMID:25532697 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions ISO Sulindac analog binds to and results in decreased activity of AKR1B10 protein; Sulindac binds to and results in decreased activity of AKR1B10 protein CTD PMID:25532697 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO Sulindac results in decreased activity of AKR1C1 protein CTD PMID:19010312 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Sulindac results in decreased activity of AKR1C2 protein CTD PMID:19010312 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Sulindac results in decreased activity of AKR1C3 protein CTD PMID:19010312 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO
EXP
[AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]] which affects the susceptibility to Oxygen; AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]
[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of AKT1 mRNA
Sulindac analog results in decreased phosphorylation of AKT1 protein
CTD PMID:18924134 PMID:20371263 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt1s1 AKT1 substrate 1 decreases expression EXP Sulindac results in decreased expression of AKT1S1 mRNA CTD PMID:24136188 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression
increases expression
ISO
EXP
Sulindac results in decreased expression of AKT2 mRNA
Sulindac results in increased expression of AKT2 mRNA
CTD PMID:11906190 PMID:24136188 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alb albumin multiple interactions EXP [Sulindac co-treated with REN2] results in increased expression of ALB protein CTD PMID:12586211 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ALDH1A1 mRNA CTD PMID:20371263 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ALDH1L1 mRNA CTD PMID:20371263 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression EXP Sulindac results in decreased expression of ALDH3A2 mRNA CTD PMID:24136188 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ALDH6A1 mRNA CTD PMID:20371263 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Alg14 ALG14, UDP-N-acetylglucosaminyltransferase subunit increases expression EXP Sulindac results in increased expression of ALG14 mRNA CTD PMID:24136188 NCBI chr 2:209,368,285...209,445,425
Ensembl chr 2:209,368,312...209,445,431
JBrowse link
G Alox15 arachidonate 15-lipoxygenase increases expression
multiple interactions
increases activity
ISO Sulindac results in increased expression of ALOX15 protein
[Sulindac results in increased expression of ALOX15 protein] which results in increased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid
Sulindac results in increased activity of ALOX15 protein
CTD PMID:10904086 PMID:11406566 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO Sulindac promotes the reaction [cobaltous chloride results in decreased expression of ALPL protein]; Sulindac promotes the reaction [Deferoxamine results in decreased expression of ALPL protein] CTD PMID:21882223 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 multiple interactions ISO [Sulindac co-treated with Putrescine] results in decreased activity of AMD1 protein CTD PMID:17474863 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Amt aminomethyltransferase increases expression EXP Sulindac results in increased expression of AMT mRNA CTD PMID:24136188 NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126
JBrowse link
G Amz2 archaelysin family metallopeptidase 2 decreases expression EXP Sulindac results in decreased expression of AMZ2 mRNA CTD PMID:24136188 NCBI chr10:94,401,546...94,412,116
Ensembl chr10:94,401,579...94,412,114
JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Sulindac results in decreased expression of ANGPTL3 mRNA CTD PMID:32535746 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Ankrd11 ankyrin repeat domain containing 11 increases expression ISO Sulindac results in increased expression of ANKRD11 mRNA CTD PMID:11906190 NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962
JBrowse link
G Ankrd24 ankyrin repeat domain 24 increases expression EXP Sulindac results in increased expression of ANKRD24 mRNA CTD PMID:24136188 NCBI chr 7:8,061,634...8,081,142
Ensembl chr 7:8,061,953...8,081,142
JBrowse link
G Ankrd28 ankyrin repeat domain 28 decreases expression EXP Sulindac results in decreased expression of ANKRD28 mRNA CTD PMID:24136188 NCBI chr16:6,918,487...7,050,244
Ensembl chr16:6,914,336...7,050,249
JBrowse link
G Ankrd40 ankyrin repeat domain 40 increases expression EXP Sulindac results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr10:79,282,075...79,295,322
Ensembl chr10:79,282,075...79,295,320
JBrowse link
G Ap1ar adaptor-related protein complex 1 associated regulatory protein increases expression EXP Sulindac results in increased expression of AP1AR mRNA CTD PMID:24136188 NCBI chr 2:216,276,631...216,309,020
Ensembl chr 2:216,276,631...216,309,013
JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 increases expression EXP Sulindac results in increased expression of AP3D1 mRNA CTD PMID:24136188 NCBI chr 7:8,970,249...9,005,651
Ensembl chr 7:8,970,291...9,005,643
JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions
increases expression
EXP Sulindac inhibits the reaction [Azoxymethane results in decreased expression of APC mRNA]
Sulindac results in increased expression of APC protein
CTD PMID:11076880 PMID:12458338 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apob apolipoprotein B decreases secretion ISO Sulindac results in decreased secretion of APOB protein CTD PMID:32535746 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc3 apolipoprotein C3 decreases secretion ISO Sulindac results in decreased secretion of APOC3 protein CTD PMID:32535746 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of APP mRNA] CTD PMID:15190207 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP Sulindac results in decreased expression of AQP1 mRNA CTD PMID:24136188 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Arglu1 arginine and glutamate rich 1 increases expression ISO Sulindac results in increased expression of ARGLU1 mRNA CTD PMID:11906190 NCBI chr16:80,753,300...80,777,350
Ensembl chr16:80,753,315...80,777,349
JBrowse link
G Arid1b AT-rich interaction domain 1B decreases expression EXP Sulindac results in decreased expression of ARID1B mRNA CTD PMID:24136188 NCBI chr 1:45,567,991...45,923,644
Ensembl chr 1:45,563,623...45,923,493
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 increases expression EXP Sulindac results in increased expression of ARL1 mRNA CTD PMID:24136188 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO Sulindac results in increased expression of ARRDC3 mRNA CTD PMID:11906190 NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Sulindac results in increased expression of ASNS mRNA CTD PMID:11906190 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 increases expression EXP Sulindac results in increased expression of ASNSD1 mRNA CTD PMID:24136188 NCBI chr 9:48,126,808...48,139,073
Ensembl chr 9:48,126,808...48,139,073
JBrowse link
G Ate1 arginyltransferase 1 decreases expression EXP Sulindac results in decreased expression of ATE1 mRNA CTD PMID:24136188 NCBI chr 1:184,961,548...185,081,112
Ensembl chr 1:184,963,562...185,080,908
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Sulindac results in increased expression of ATF3 mRNA CTD PMID:11906190 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Sulindac results in increased expression of ATF4 mRNA CTD PMID:11906190 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Sulindac results in increased expression of ATF6 mRNA CTD PMID:32535746 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg3 autophagy related 3 increases expression EXP Sulindac results in increased expression of ATG3 mRNA CTD PMID:24136188 NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 decreases expression ISO Sulindac results in decreased expression of ATP2A1 mRNA CTD PMID:11906190 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression EXP Sulindac results in increased expression of ATP6V1A mRNA CTD PMID:24136188 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 increases expression EXP Sulindac results in increased expression of ATP6V1E1 mRNA CTD PMID:24136188 NCBI chr 4:154,022,358...154,044,486
Ensembl chr 4:154,022,358...154,044,584
JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of AUH mRNA CTD PMID:20371263 NCBI chr17:12,329,522...12,424,882
Ensembl chr17:12,329,524...12,424,896
JBrowse link
G Aurka aurora kinase A decreases expression ISO Sulindac results in decreased expression of AURKA mRNA CTD PMID:11906190 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Aurkaip1 aurora kinase A interacting protein 1 decreases expression EXP Sulindac results in decreased expression of AURKAIP1 mRNA CTD PMID:24136188 NCBI chr 5:166,435,177...166,436,888
Ensembl chr 5:166,417,508...166,436,882
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 decreases expression EXP Sulindac results in decreased expression of B4GALT1 mRNA CTD PMID:24136188 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
decreases expression
ISO Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of BAD protein]
Sulindac results in decreased expression of BAD protein
CTD PMID:12566304 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
affects localization
ISO SB 203580 inhibits the reaction [Sulindac affects the localization of BAK1 protein] CTD PMID:17136320 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
affects localization
increases response to substance
ISO SB 203580 inhibits the reaction [Sulindac affects the localization of BAX protein]
Sulindac results in increased expression of BAX protein
BAX protein results in increased susceptibility to Sulindac
CTD PMID:11062132 PMID:17136320 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Sulindac results in increased expression of BBC3 mRNA CTD PMID:11906190 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcap29 B-cell receptor-associated protein 29 increases expression ISO Sulindac results in increased expression of BCAP29 mRNA CTD PMID:11906190 NCBI chr 6:48,182,702...48,222,698
Ensembl chr 6:48,182,706...48,222,720
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
Sulindac results in decreased expression of BCL2 protein
[Olive Oil co-treated with Sulindac] results in decreased expression of BCL2 protein
[Sulindac results in increased abundance of Reactive Oxygen Species] which results in increased cleavage of BCL2 protein
CTD PMID:10223192 PMID:15309441 PMID:15793875 PMID:17136320 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO [Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein; Acetylcysteine inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein]; MAPK8 affects the reaction [[Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein]
Sulindac results in decreased expression of BCL2L1 protein
CTD PMID:11062132 PMID:18281123 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO [Sulindac results in increased abundance of Reactive Oxygen Species] which results in decreased expression of BIRC2 protein CTD PMID:17136320 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO [Sulindac results in increased abundance of Reactive Oxygen Species] which results in decreased expression of BIRC3 protein CTD PMID:17136320 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO [Sulindac co-treated with Arsenic Trioxide] results in decreased expression of BIRC5 protein; [Sulindac co-treated with Vorinostat] results in decreased expression of BIRC5 mRNA; [Sulindac co-treated with Vorinostat] results in decreased expression of BIRC5 protein; [Sulindac results in increased abundance of Reactive Oxygen Species] which results in decreased expression of BIRC5 protein; BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein modified form]; BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein]
Sulindac results in decreased expression of BIRC5 mRNA; Sulindac results in decreased expression of BIRC5 protein
CTD PMID:11906190 PMID:14610217 PMID:17136320 PMID:17401459 PMID:18156316 More... NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blmh bleomycin hydrolase increases expression EXP Sulindac results in increased expression of BLMH mRNA CTD PMID:24136188 NCBI chr10:61,772,112...61,815,212
Ensembl chr10:61,758,478...61,815,212
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP Sulindac results in increased expression of BNIP3L mRNA CTD PMID:24136188 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Borcs7 BLOC-1 related complex subunit 7 increases expression EXP Sulindac results in increased expression of BORCS7 mRNA CTD PMID:24136188 NCBI chr 1:245,564,347...245,578,182
Ensembl chr 1:245,564,369...245,579,343
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO Sulindac results in decreased expression of BRCA1 mRNA CTD PMID:16273229 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brd4 bromodomain containing 4 decreases expression ISO Sulindac results in decreased expression of BRD4 mRNA CTD PMID:11906190 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Btbd1 BTB domain containing 1 increases expression EXP Sulindac results in increased expression of BTBD1 mRNA CTD PMID:24136188 NCBI chr 1:135,734,549...135,773,067
Ensembl chr 1:135,734,589...135,771,981
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression EXP Sulindac results in increased expression of BZW1 mRNA CTD PMID:24136188 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
JBrowse link
G Bzw2 basic leucine zipper and W2 domains 2 decreases expression ISO Sulindac results in decreased expression of BZW2 mRNA CTD PMID:11093808 NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628
JBrowse link
G C17h7orf25 similar to human chromosome 7 open reading frame 25 decreases expression EXP Sulindac results in decreased expression of C17H7ORF25 mRNA CTD PMID:24136188 NCBI chr17:50,543,231...50,549,880
Ensembl chr17:50,542,858...50,549,976
JBrowse link
G C18h18orf32 similar to human chromosome 18 open reading frame 32 decreases expression EXP Sulindac results in decreased expression of C18H18ORF32 mRNA CTD PMID:24136188 NCBI chr18:68,586,278...68,594,851
Ensembl chr18:68,586,211...68,596,787
JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 decreases expression EXP Sulindac results in decreased expression of C1GALT1C1 mRNA CTD PMID:24136188 NCBI chr  X:117,378,123...117,382,620
Ensembl chr  X:117,375,525...117,382,787
JBrowse link
G C2h1orf52 similar to human chromosome 1 open reading frame 52 increases expression ISO Sulindac results in increased expression of C1ORF52 mRNA CTD PMID:11906190 NCBI chr 2:234,853,378...234,860,045
Ensembl chr 2:234,853,410...234,860,040
JBrowse link
G C4b complement C4B decreases expression EXP Sulindac results in decreased expression of C4B mRNA CTD PMID:24136188 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G Calm3 calmodulin 3 decreases expression
increases expression
ISO
EXP
Sulindac results in decreased expression of CALM3 mRNA
Sulindac results in increased expression of CALM3 mRNA
CTD PMID:11906190 PMID:24136188 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Car9 carbonic anhydrase 9 decreases expression ISO Sulindac analog results in decreased expression of CA9 mRNA CTD PMID:18924134 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
ISO
EXP
[Sulindac co-treated with arsenic trioxide] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased activity of CASP3 protein]
epigallocatechin gallate promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CASP3 protein]]; kaempferol promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CASP3 protein]]; Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CASP3 protein]
Sulindac results in increased activity of CASP3 protein
[Sulindac results in increased expression of IL24 protein] which results in increased expression of CASP3 protein
CTD PMID:12017300 PMID:15713900 PMID:15946692 PMID:18281123 PMID:29999212 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Sulindac co-treated with TNFSF10 protein] results in increased activity of CASP8 protein CTD PMID:21171083 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO [Sulindac co-treated with arsenic trioxide] results in increased activity of CASP9 protein
[Sulindac results in increased expression of IL24 protein] which results in increased expression of CASP9 protein
Sulindac results in increased activity of CASP9 protein
CTD PMID:15713900 PMID:18281123 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cast calpastatin decreases expression EXP Sulindac results in decreased expression of CAST mRNA CTD PMID:24136188 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cavin3 caveolae associated protein 3 increases expression ISO Sulindac results in increased expression of CAVIN3 mRNA CTD PMID:11906190 NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Sulindac inhibits the reaction [IL1B protein results in increased expression of CCL5 mRNA]; Sulindac inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:16159934 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Sulindac results in decreased expression of CCNA2 protein CTD PMID:16488075 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Sulindac results in decreased expression of CCNB1 mRNA CTD PMID:11906190 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO CTNNB1 protein affects the reaction [Sulindac results in decreased expression of CCND1 protein]; Sulindac inhibits the reaction [TNF protein results in increased expression of CCND1 protein]
[Sulindac co-treated with Plant Extracts] results in decreased expression of CCND1 protein
CTD PMID:11504793 PMID:11593435 PMID:12351151 PMID:12584176 PMID:15020200 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Sulindac results in decreased expression of CCNE1 protein CTD PMID:16488075 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccnj cyclin J decreases expression ISO Sulindac results in decreased expression of CCNJ mRNA CTD PMID:11906190 NCBI chr 1:239,659,588...239,677,367 JBrowse link
G Ccnq cyclin Q decreases expression EXP Sulindac results in decreased expression of CCNQ mRNA CTD PMID:24136188 NCBI chr10:63,646,532...63,647,695
Ensembl chr10:63,646,527...63,647,961
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 decreases expression EXP Sulindac results in decreased expression of CCT4 mRNA CTD PMID:24136188 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
JBrowse link
G Cdc37l1 cell division cycle 37-like 1 decreases expression EXP Sulindac results in decreased expression of CDC37L1 mRNA CTD PMID:24136188 NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:226,705,003...226,761,175
JBrowse link
G Cdc42ep1 CDC42 effector protein 1 increases expression ISO Sulindac results in increased expression of CDC42EP1 mRNA CTD PMID:11906190 NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Sulindac results in decreased expression of CDK1 mRNA CTD PMID:16273229 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity
ISO Sulindac promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein]
Sulindac results in decreased activity of CDK2 protein
CTD PMID:14566837 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
decreases expression
ISO
EXP
CTNNB1 protein affects the reaction [Sulindac results in decreased expression of CDK4 protein]
[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CDK4 mRNA
CTD PMID:17292881 PMID:18291362 PMID:20371263 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO Sulindac results in decreased expression of CDK6 protein CTD PMID:16488075 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
increases response to substance
increases activity
decreases activity
ISO
EXP
[Sulindac co-treated with epigallocatechin gallate] results in increased expression of CDKN1A mRNA; CDKN1A protein promotes the reaction [Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein]; CSK protein affects the reaction [Sulindac results in increased expression of CDKN1A protein]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of APP mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of CTSB mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of GBA1 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of GRN mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of IL32 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of ITGB3 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of LGALS3 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of LGALS3BP mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of SAA1 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of SHC1 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of SOD2 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of TGM2 mRNA]; Sulindac promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein]
Sulindac results in increased expression of CDKN1A mRNA; Sulindac results in increased expression of CDKN1A protein
[Azoxymethane co-treated with Sulindac] results in increased expression of CDKN1A protein
CDKN1A protein results in increased susceptibility to Sulindac
Sulindac results in increased activity of CDKN1A protein
Sulindac results in decreased activity of CDKN1A protein
CTD PMID:11507085 PMID:12628509 PMID:14566837 PMID:15190207 PMID:15688007 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP Sulindac inhibits the reaction [Azoxymethane results in decreased expression of CDKN1B protein] CTD PMID:12189186 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP Sulindac inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A mRNA] CTD PMID:12189186 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cep15 centrosomal protein 15 decreases expression EXP Sulindac results in decreased expression of CEP15 mRNA CTD PMID:24136188 NCBI chr15:12,815,159...12,835,115
Ensembl chr15:12,818,385...12,833,838
JBrowse link
G Cfl2 cofilin 2 decreases expression EXP Sulindac results in decreased expression of CFL2 mRNA CTD PMID:24136188 NCBI chr 6:72,355,664...72,359,709
Ensembl chr 6:72,355,664...72,359,674
JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 decreases expression EXP Sulindac results in decreased expression of CHCHD3 mRNA CTD PMID:24136188 NCBI chr 4:61,360,352...61,616,850
Ensembl chr 4:61,360,353...61,616,847
JBrowse link
G Chchd5 coiled-coil-helix-coiled-coil-helix domain containing 5 increases expression EXP Sulindac results in increased expression of CHCHD5 mRNA CTD PMID:24136188 NCBI chr 3:116,361,845...116,372,238
Ensembl chr 3:116,361,885...116,367,169
JBrowse link
G Chd8 chromodomain helicase DNA binding protein 8 decreases expression EXP Sulindac results in decreased expression of CHD8 mRNA CTD PMID:24136188 NCBI chr15:24,905,789...24,965,461
Ensembl chr15:24,905,789...24,951,285
JBrowse link
G Chmp2a charged multivesicular body protein 2A decreases expression EXP Sulindac results in decreased expression of CHMP2A mRNA CTD PMID:24136188 NCBI chr 1:73,660,045...73,662,894
Ensembl chr 1:73,660,046...73,662,452
JBrowse link
G Chrac1 chromatin accessibility complex subunit 1 increases expression EXP Sulindac results in increased expression of CHRAC1 mRNA CTD PMID:24136188 NCBI chr 7:105,013,047...105,016,435
Ensembl chr 7:105,013,015...105,017,136
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Sulindac inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit increases expression EXP Sulindac results in increased expression of CLPP mRNA CTD PMID:24136188 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
JBrowse link
G Clu clusterin affects expression ISO Sulindac affects the expression of CLU protein CTD PMID:12388792 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 increases expression EXP Sulindac results in increased expression of CMTM6 mRNA CTD PMID:24136188 NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033
JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 decreases expression EXP Sulindac results in decreased expression of CNGB1 mRNA CTD PMID:24136188 NCBI chr19:9,726,595...9,791,111
Ensembl chr19:9,726,595...9,791,173
JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 increases expression ISO Sulindac results in increased expression of CNNM4 mRNA CTD PMID:11906190 NCBI chr 9:38,711,726...38,750,942
Ensembl chr 9:38,711,710...38,750,942
JBrowse link
G Cnot6 CCR4-NOT transcription complex, subunit 6 decreases expression EXP Sulindac results in decreased expression of CNOT6 mRNA CTD PMID:24136188 NCBI chr10:33,978,785...34,031,025
Ensembl chr10:33,980,831...34,031,025
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression ISO Sulindac results in increased expression of COL1A2 mRNA CTD PMID:18499699 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Sulindac results in increased expression of COL5A2 mRNA CTD PMID:18499699 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Sulindac results in increased expression of COL6A2 mRNA CTD PMID:18499699 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression ISO Sulindac results in increased expression of COL6A3 mRNA CTD PMID:18499699 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471
JBrowse link
G Commd3 COMM domain containing 3 increases expression EXP Sulindac results in increased expression of COMMD3 mRNA CTD PMID:24136188 NCBI chr17:81,327,444...81,331,191
Ensembl chr17:81,327,405...81,331,177
JBrowse link
G Commd5 COMM domain containing 5 increases expression EXP Sulindac results in increased expression of COMMD5 mRNA CTD PMID:24136188 NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764
JBrowse link
G Cops7a COP9 signalosome subunit 7A increases expression EXP Sulindac results in increased expression of COPS7A mRNA CTD PMID:24136188 NCBI chr 4:157,766,626...157,792,632
Ensembl chr 4:157,766,588...157,773,948
JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 increases expression EXP Sulindac results in increased expression of COX15 mRNA CTD PMID:24136188 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
JBrowse link
G Cpne1 copine 1 decreases expression ISO Sulindac results in decreased expression of CPNE1 mRNA CTD PMID:11906190 NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636
JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 increases expression EXP Sulindac results in increased expression of CPSF3 mRNA CTD PMID:24136188 NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 increases expression EXP Sulindac results in increased expression of CREB3L3 mRNA CTD PMID:24136188 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
JBrowse link
G Crebzf CREB/ATF bZIP transcription factor increases expression EXP Sulindac results in increased expression of CREBZF mRNA CTD PMID:24136188 NCBI chr 1:144,416,864...144,423,540
Ensembl chr 1:144,417,446...144,428,553
JBrowse link
G Cry2 cryptochrome circadian regulator 2 decreases expression EXP Sulindac results in decreased expression of CRY2 mRNA CTD PMID:24136188 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
JBrowse link
G Csf1 colony stimulating factor 1 decreases expression EXP Sulindac results in decreased expression of CSF1 mRNA CTD PMID:24136188 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csk C-terminal Src kinase multiple interactions ISO
EXP
CSK protein affects the reaction [Sulindac results in increased expression of CDKN1A protein]
[[Azoxymethane co-treated with Sulindac] results in increased expression of CSK protein] which results in increased phosphorylation of and results in decreased activity of SRC protein; [Azoxymethane co-treated with Sulindac] results in increased expression of CSK protein
CTD PMID:18644992 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression
increases expression
ISO
EXP
Sulindac results in decreased expression of CSNK2A1 mRNA
Sulindac results in increased expression of CSNK2A1 mRNA
CTD PMID:11906190 PMID:24136188 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 increases expression ISO Sulindac results in increased expression of CSNK2A2 mRNA CTD PMID:11906190 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression
ISO
EXP
CTNNB1 protein affects the reaction [Sulindac results in decreased expression of CCND1 protein]; CTNNB1 protein affects the reaction [Sulindac results in decreased expression of CDK4 protein]; CTNNB1 protein affects the reaction [Sulindac results in decreased expression of MYC protein]; Sulindac results in decreased activity of [LEF1 protein binds to CTNNB1 protein]
epigallocatechin gallate promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTNNB1 protein]]; kaempferol promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTNNB1 protein]]; Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTNNB1 protein]
Sulindac results in decreased expression of CTNNB1 protein
[Sulindac co-treated with Plant Extracts] results in decreased expression of CTNNB1 protein
CTD PMID:10223192 PMID:11751639 PMID:12351151 PMID:18291362 PMID:29999212 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsb cathepsin B multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of CTSB mRNA] CTD PMID:15190207 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO Sulindac inhibits the reaction [IFNG protein results in increased expression of CXCL9 mRNA] CTD PMID:17010317 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity
increases activity
ISO
EXP
Sulindac results in increased expression of CYP1A1 mRNA
Sulindac results in decreased activity of CYP1A1 protein
Sulindac results in increased activity of CYP1A1 protein
CTD PMID:16531450 PMID:17985343 PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
decreases expression
ISO
EXP
Sulindac results in increased expression of CYP1A2 mRNA
Sulindac results in decreased expression of CYP1A2 mRNA
CTD PMID:16531450 PMID:17985343 PMID:24136188 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
decreases activity
increases activity
ISO
EXP
Sulindac results in increased expression of CYP1B1 mRNA
Sulindac results in decreased activity of CYP1B1 protein
Sulindac results in increased activity of CYP1B1 protein
CTD PMID:16531450 PMID:17985343 PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CYP2D4 mRNA CTD PMID:20371263 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CYP2J4 mRNA CTD PMID:20371263 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CYP4B1 mRNA CTD PMID:20371263 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CYP8B1 mRNA CTD PMID:20371263 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Dcn decorin decreases expression ISO Sulindac results in decreased expression of DCN mRNA CTD PMID:11507085 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Dctn5 dynactin subunit 5 decreases expression EXP Sulindac results in decreased expression of DCTN5 mRNA CTD PMID:24136188 NCBI chr 1:176,689,176...176,705,907
Ensembl chr 1:176,689,156...176,705,906
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO [Sulindac co-treated with epigallocatechin gallate] results in increased expression of DDIT3 mRNA
Sulindac results in increased expression of DDIT3 mRNA
CTD PMID:12628509 PMID:24136188 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx1 DEAD-box helicase 1 decreases expression EXP Sulindac results in decreased expression of DDX1 mRNA CTD PMID:24136188 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 increases expression EXP Sulindac results in increased expression of DEGS1 mRNA CTD PMID:24136188 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664
JBrowse link
G Dffb DNA fragmentation factor subunit beta affects localization ISO Sulindac affects the localization of DFFB protein CTD PMID:15946692 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628
JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases activity ISO Sulindac results in decreased activity of DHRS11 protein CTD PMID:30926317 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295
JBrowse link
G Dhx36 DEAH-box helicase 36 increases expression EXP Sulindac results in increased expression of DHX36 mRNA CTD PMID:24136188 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Dip2c disco-interacting protein 2 homolog C increases expression EXP Sulindac results in increased expression of DIP2C mRNA CTD PMID:24136188 NCBI chr17:60,647,346...61,032,467
Ensembl chr17:60,649,065...61,032,305
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 increases expression EXP Sulindac results in increased expression of DLG1 mRNA CTD PMID:24136188 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 increases expression EXP Sulindac results in increased expression of DNAJC10 mRNA CTD PMID:24136188 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 increases expression EXP Sulindac results in increased expression of DNAJC15 mRNA CTD PMID:24136188 NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675
JBrowse link
G Dpys dihydropyrimidinase increases expression ISO Sulindac results in increased expression of DPYS mRNA CTD PMID:11906190 NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression EXP Sulindac results in decreased expression of DYNLL1 mRNA CTD PMID:24136188 NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Sulindac results in decreased expression of E2F1 protein CTD PMID:16488075 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ECI2 mRNA CTD PMID:20371263 NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of BAD protein]; Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:12566304 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO Sulindac results in decreased expression of EHMT2 mRNA CTD PMID:11906190 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO Sulindac results in increased expression of EIF2AK3 mRNA CTD PMID:32535746 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression EXP Sulindac results in increased expression of EIF5B mRNA CTD PMID:24136188 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
JBrowse link
G Elapor2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 increases expression ISO Sulindac results in increased expression of ELAPOR2 mRNA CTD PMID:11906190 NCBI chr 4:24,613,163...24,805,729
Ensembl chr 4:24,613,163...24,805,729
JBrowse link
G Eloc elongin C increases expression EXP Sulindac results in increased expression of ELOC mRNA CTD PMID:24136188 NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890
JBrowse link
G Endog endonuclease G affects localization ISO Sulindac affects the localization of ENDOG protein CTD PMID:15946692 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease decreases expression ISO Sulindac results in decreased expression of ERCC5 mRNA CTD PMID:11906190 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO Sulindac results in increased expression of ERN1 mRNA CTD PMID:32535746 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression EXP Sulindac results in decreased expression of ERRFI1 mRNA CTD PMID:24136188 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Ess2 ess-2 splicing factor homolog increases expression ISO Sulindac results in increased expression of ESS2 mRNA CTD PMID:11906190 NCBI chr11:83,075,893...83,085,849
Ensembl chr11:83,075,925...83,084,846
JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase decreases expression EXP Sulindac results in decreased expression of ETFDH mRNA CTD PMID:24136188 NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor increases expression ISO Sulindac results in increased expression of ETS1 mRNA CTD PMID:11906190 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Exoc3 exocyst complex component 3 decreases expression EXP Sulindac results in decreased expression of EXOC3 mRNA CTD PMID:24136188 NCBI chr 1:29,091,298...29,122,056
Ensembl chr 1:29,091,294...29,122,045
JBrowse link
G Exoc7 exocyst complex component 7 increases expression EXP Sulindac results in increased expression of EXOC7 mRNA CTD PMID:24136188 NCBI chr10:101,521,630...101,540,425
Ensembl chr10:101,520,927...101,540,561
JBrowse link
G Exosc5 exosome component 5 decreases expression EXP Sulindac results in decreased expression of EXOSC5 mRNA CTD PMID:24136188 NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265
JBrowse link
G Exosc7 exosome component 7 decreases expression EXP Sulindac results in decreased expression of EXOSC7 mRNA CTD PMID:24136188 NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270
JBrowse link
G Fam219b family with sequence similarity 219, member B decreases expression EXP Sulindac results in decreased expression of FAM219B mRNA CTD PMID:24136188 NCBI chr 8:57,941,327...57,946,916
Ensembl chr 8:57,941,294...57,946,906
JBrowse link
G Fam241b family with sequence similarity 241 member B increases expression EXP Sulindac results in increased expression of FAM241B mRNA CTD PMID:24136188 NCBI chr20:30,052,315...30,055,247
Ensembl chr20:30,052,324...30,055,084
JBrowse link
G Fasn fatty acid synthase increases expression ISO Sulindac results in increased expression of FASN mRNA CTD PMID:32535746 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 increases expression EXP Sulindac results in increased expression of FBXL4 mRNA CTD PMID:24136188 NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443
JBrowse link
G Fbxo42 F-box protein 42 increases expression ISO Sulindac results in increased expression of FBXO42 mRNA CTD PMID:11906190 NCBI chr 5:153,451,162...153,509,564
Ensembl chr 5:153,451,153...153,506,342
JBrowse link
G Fbxo6 F-box protein 6 decreases expression EXP Sulindac results in decreased expression of FBXO6 mRNA CTD PMID:24136188 NCBI chr 5:158,576,729...158,582,520
Ensembl chr 5:158,576,759...158,582,525
JBrowse link
G Fhl2 four and a half LIM domains 2 increases expression ISO Sulindac results in increased expression of FHL2 mRNA CTD PMID:11906190 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A decreases expression EXP Sulindac results in decreased expression of FKBP1A mRNA CTD PMID:24136188 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fli1 Fli-1 proto-oncogene, ETS transcription factor decreases expression EXP Sulindac results in decreased expression of FLI1 mRNA CTD PMID:24136188 NCBI chr 8:30,831,422...30,950,468
Ensembl chr 8:30,832,753...30,950,433
JBrowse link
G Flnb filamin B increases expression EXP Sulindac results in increased expression of FLNB mRNA CTD PMID:24136188 NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 affects metabolic processing
increases metabolic processing
multiple interactions
ISO FMO3 gene polymorphism affects the metabolism of Sulindac
FMO3 protein results in increased metabolism of Sulindac
FMO3 gene polymorphism results in decreased metabolism of and results in increased susceptibility to Sulindac
CTD PMID:15623613 PMID:17050781 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Sulindac results in decreased expression of FOS protein CTD PMID:15020200 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Sulindac results in increased expression of FTH1 mRNA CTD PMID:11093808 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression EXP Sulindac results in decreased expression of FTL1 mRNA CTD PMID:24136188 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Fxn frataxin increases expression EXP Sulindac results in increased expression of FXN mRNA CTD PMID:24136188 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Sulindac results in increased expression of GADD45A mRNA CTD PMID:11906190 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gal galanin and GMAP prepropeptide affects expression ISO Sulindac affects the expression of GAL protein CTD PMID:12388792 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Galk1 galactokinase 1 increases expression EXP Sulindac results in increased expression of GALK1 mRNA CTD PMID:24136188 NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337
JBrowse link
G Gap43 growth associated protein 43 affects expression ISO Sulindac affects the expression of GAP43 protein CTD PMID:12388792 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gatad1 GATA zinc finger domain containing 1 increases expression EXP Sulindac results in increased expression of GATAD1 mRNA CTD PMID:24136188 NCBI chr 4:30,507,530...30,519,107
Ensembl chr 4:30,507,538...30,519,107
JBrowse link
G Gatad2a GATA zinc finger domain containing 2A increases expression EXP Sulindac results in increased expression of GATAD2A mRNA CTD PMID:24136188 NCBI chr16:19,429,578...19,520,320
Ensembl chr16:19,429,578...19,519,587
JBrowse link
G Gatd3a glutamine amidotransferase class 1 domain containing 3A decreases expression ISO Sulindac results in decreased expression of GATD3 mRNA CTD PMID:11906190 NCBI chr20:10,514,793...10,522,894
Ensembl chr20:10,514,744...10,522,885
JBrowse link
G Gba1 glucosylceramidase beta 1 multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of GBA1 mRNA] CTD PMID:15190207 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Gcdh glutaryl-CoA dehydrogenase multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of GCDH mRNA CTD PMID:20371263 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
affects expression
ISO Acetylcysteine inhibits the reaction [Sulindac results in increased expression of GCLC protein]
Sulindac affects the expression of GCLC mRNA
CTD PMID:11820781 PMID:15946948 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 increases expression ISO Sulindac results in increased expression of GCNT1 mRNA CTD PMID:11093808 NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Sulindac results in increased expression of GDF15 mRNA; Sulindac results in increased expression of GDF15 protein CTD PMID:11906190 PMID:11984525 PMID:15180942 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Ghitm growth hormone inducible transmembrane protein increases expression EXP Sulindac results in increased expression of GHITM mRNA CTD PMID:24136188 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879
JBrowse link
G Ghr growth hormone receptor multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of GHR mRNA CTD PMID:20371263 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Glo1 glyoxalase 1 decreases activity ISO Sulindac results in decreased activity of GLO1 protein CTD PMID:17243824 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gnas GNAS complex locus increases expression EXP Sulindac results in increased expression of GNAS mRNA CTD PMID:24136188 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gnl3l G protein nucleolar 3 like decreases expression EXP Sulindac results in decreased expression of GNL3L mRNA CTD PMID:24136188 NCBI chr  X:19,961,277...19,994,454
Ensembl chr  X:19,958,603...19,994,508
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression EXP Sulindac results in decreased expression of GNMT mRNA CTD PMID:24136188 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of GPX3 mRNA CTD PMID:20371263 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO Sulindac results in increased expression of GRB10 mRNA CTD PMID:11906190 NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression EXP Sulindac results in increased expression of GRB2 mRNA CTD PMID:24136188 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 affects expression EXP Sulindac affects the expression of GRIN1 protein CTD PMID:15123337 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B affects expression EXP Sulindac affects the expression of GRIN2B protein CTD PMID:15123337 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression EXP Sulindac results in decreased expression of GRK6 mRNA CTD PMID:24136188 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644
JBrowse link
G Grn granulin precursor multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of GRN mRNA] CTD PMID:15190207 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO Sulindac results in decreased phosphorylation of GSK3B protein CTD PMID:11593435 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of GSTM2 mRNA CTD PMID:20371263 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP Sulindac results in increased expression of GSTT1 protein CTD PMID:9729437 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gtf2b general transcription factor IIB increases expression
decreases expression
ISO
EXP
Sulindac results in increased expression of GTF2B mRNA
Sulindac results in decreased expression of GTF2B mRNA
CTD PMID:11906190 PMID:24136188 NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Arsenic Trioxide co-treated with Sulindac] results in increased phosphorylation of H2AX protein CTD PMID:18636201 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2az1 H2A.Z variant histone 1 increases expression EXP Sulindac results in increased expression of H2AZ1 mRNA CTD PMID:24136188 NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression EXP Sulindac results in decreased expression of HADHB mRNA CTD PMID:24136188 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Helz2 helicase with zinc finger 2 decreases expression EXP Sulindac results in decreased expression of HELZ2 mRNA CTD PMID:24136188 NCBI chr 3:168,338,813...168,353,219
Ensembl chr 3:168,338,813...168,353,159
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Sulindac results in increased expression of HERPUD1 mRNA CTD PMID:11093808 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
ISO [AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]] which affects the susceptibility to Oxygen; AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]
Sulindac analog results in decreased expression of HIF1A mRNA; Sulindac analog results in decreased expression of HIF1A protein
CTD PMID:18924134 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression EXP Sulindac results in increased expression of HIGD1A mRNA CTD PMID:24136188 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443
JBrowse link
G Hlcs holocarboxylase synthetase decreases expression ISO Sulindac results in decreased expression of HLCS mRNA CTD PMID:11906190 NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
JBrowse link
G Hmgb3 high mobility group box 3 increases expression EXP Sulindac results in increased expression of HMGB3 mRNA CTD PMID:24136188 NCBI chr  X:149,296,303...149,301,290
Ensembl chr  X:149,296,375...149,301,292
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO Sulindac results in decreased expression of HMMR mRNA CTD PMID:11906190 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sulindac promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]]; pyrazolanthrone inhibits the reaction [Sulindac promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]]; SB 203580 inhibits the reaction [Sulindac promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]]; Sulindac promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]
Sulindac results in decreased expression of HMOX1 protein
CTD PMID:18636201 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of HNF4A mRNA CTD PMID:20371263 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of HSD17B4 mRNA CTD PMID:20371263 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Sulindac results in increased activity of HSF1 protein CTD PMID:10328874 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP Sulindac results in increased expression of HSPA9 mRNA CTD PMID:24136188 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO Sulindac results in decreased expression of ICAM1 protein CTD PMID:18059344 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression EXP Sulindac results in decreased expression of IFI27 mRNA CTD PMID:24136188 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 decreases expression EXP Sulindac results in decreased expression of IFITM3 mRNA CTD PMID:24136188 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 decreases expression EXP Sulindac results in decreased expression of IFNAR1 mRNA CTD PMID:24136188 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979
JBrowse link
G Ifng interferon gamma multiple interactions ISO Sulindac inhibits the reaction [IFNG protein results in increased expression of CXCL9 mRNA] CTD PMID:17010317 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Iftap intraflagellar transport associated protein increases expression EXP Sulindac results in increased expression of IFTAP mRNA CTD PMID:24136188 NCBI chr 3:87,812,068...87,906,517
Ensembl chr 3:87,817,408...87,906,547
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta decreases activity ISO Sulindac results in decreased activity of IKBKB protein CTD PMID:19526344 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 increases expression EXP Sulindac results in increased expression of IL11RA1 mRNA CTD PMID:24136188 NCBI chr 5:56,931,824...56,941,408
Ensembl chr 5:56,935,516...56,941,408
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of IL1A mRNA CTD PMID:20371263 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO
EXP
[Sulindac co-treated with epigallocatechin gallate] results in decreased expression of IL1B mRNA; Sulindac inhibits the reaction [IL1B protein results in increased abundance of Hyaluronic Acid]; Sulindac inhibits the reaction [IL1B protein results in increased expression of CCL5 mRNA]
Sulindac results in increased expression of IL1B
Sulindac results in decreased expression of IL1B protein
Sulindac results in decreased expression of IL1B mRNA
CTD PMID:10328874 PMID:11318944 PMID:12628509 PMID:15123337 PMID:16159934 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il24 interleukin 24 multiple interactions
increases expression
ISO Sulindac promotes the reaction [IL24 protein results in increased phosphorylation of MAPK8 protein]
[Sulindac results in increased expression of IL24 protein] which results in increased expression of CASP3 protein; [Sulindac results in increased expression of IL24 protein] which results in increased expression of CASP9 protein; Sulindac results in increased expression of IL24 protein
CTD PMID:15713900 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of IL6 mRNA
Sulindac results in increased expression of IL6
CTD PMID:20371263 PMID:24136188 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilk integrin-linked kinase decreases activity ISO Sulindac results in decreased activity of ILK protein CTD PMID:11593435 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E increases expression ISO Sulindac results in increased expression of INPP5E mRNA CTD PMID:11906190 NCBI chr 3:9,216,776...9,229,539
Ensembl chr 3:9,216,776...9,229,450
JBrowse link
G Ipmk inositol polyphosphate multikinase decreases expression EXP Sulindac results in decreased expression of IPMK mRNA CTD PMID:24136188 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of IRAK2 mRNA CTD PMID:20371263 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression EXP Sulindac results in decreased expression of IRF7 mRNA CTD PMID:24136188 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Isca1 iron-sulfur cluster assembly 1 decreases expression EXP Sulindac results in decreased expression of ISCA1 mRNA CTD PMID:24136188 NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955
JBrowse link
G Itga2 integrin subunit alpha 2 increases expression ISO Sulindac results in increased expression of ITGA2 mRNA CTD PMID:11906190 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of ITGB3 mRNA] CTD PMID:15190207 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itgb4 integrin subunit beta 4 multiple interactions ISO [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of ITGB4 mRNA CTD PMID:12628509 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
JBrowse link
G Jkamp JNK1/MAPK8-associated membrane protein decreases expression EXP Sulindac results in decreased expression of JKAMP mRNA CTD PMID:24136188 NCBI chr 6:90,648,043...90,661,985
Ensembl chr 6:90,648,160...90,662,501
JBrowse link
G Josd1 Josephin domain containing 1 decreases expression EXP Sulindac results in decreased expression of JOSD1 mRNA CTD PMID:24136188 NCBI chr 7:111,230,318...111,244,241
Ensembl chr 7:111,230,318...111,244,652
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO Sulindac results in decreased expression of JUN protein
[Sulindac co-treated with Plant Extracts] results in decreased expression of JUN protein
CTD PMID:12351151 PMID:12584176 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Sulindac results in increased expression of JUND mRNA CTD PMID:11906190 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kcnh3 potassium voltage-gated channel subfamily H member 3 decreases expression EXP Sulindac results in decreased expression of KCNH3 mRNA CTD PMID:24136188 NCBI chr 7:130,365,593...130,383,859
Ensembl chr 7:130,366,011...130,383,855
JBrowse link
G Kctd5 potassium channel tetramerization domain containing 5 increases expression EXP Sulindac results in increased expression of KCTD5 mRNA CTD PMID:24136188 NCBI chr10:13,079,216...13,105,197
Ensembl chr10:13,079,214...13,105,209
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression EXP Sulindac results in decreased expression of KEAP1 mRNA CTD PMID:24136188 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Khsrp KH-type splicing regulatory protein increases expression EXP Sulindac results in increased expression of KHSRP mRNA CTD PMID:24136188 NCBI chr 9:1,862,555...1,872,403
Ensembl chr 9:1,862,899...1,872,451
JBrowse link
G Kif14 kinesin family member 14 increases expression ISO Sulindac results in increased expression of KIF14 mRNA CTD PMID:11906190 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164
JBrowse link
G Klf5 KLF transcription factor 5 increases expression ISO Sulindac results in increased expression of KLF5 mRNA CTD PMID:11906190 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Kras KRAS proto-oncogene, GTPase affects response to substance ISO KRAS protein affects the susceptibility to Sulindac CTD PMID:11751493 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lad1 ladinin 1 increases expression ISO Sulindac results in increased expression of LAD1 mRNA CTD PMID:11507085 NCBI chr13:47,249,605...47,263,967
Ensembl chr13:47,249,605...47,263,967
JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 decreases expression EXP Sulindac results in decreased expression of LAMTOR4 mRNA CTD PMID:24136188 NCBI chr12:17,258,656...17,262,478
Ensembl chr12:17,258,623...17,262,480
JBrowse link
G Larp1b La ribonucleoprotein 1B decreases expression EXP Sulindac results in decreased expression of LARP1B mRNA CTD PMID:24136188 NCBI chr 2:123,936,057...123,969,254
Ensembl chr 2:123,935,983...123,968,896
JBrowse link
G Larp4 La ribonucleoprotein 4 increases expression ISO Sulindac results in increased expression of LARP4 mRNA CTD PMID:11906190 NCBI chr 7:131,104,470...131,152,692
Ensembl chr 7:131,101,564...131,150,811
JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of LBP mRNA CTD PMID:20371263 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Ldb1 LIM domain binding 1 increases expression ISO Sulindac results in increased expression of LDB1 mRNA CTD PMID:11906190 NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO Sulindac results in decreased activity of [LEF1 protein binds to CTNNB1 protein] CTD PMID:11751639 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase increases expression ISO Sulindac results in increased expression of LFNG mRNA CTD PMID:11906190 NCBI chr12:14,030,551...14,038,996
Ensembl chr12:14,018,333...14,039,008
JBrowse link
G Lgals3 galectin 3 multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of LGALS3 mRNA] CTD PMID:15190207 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lgals3bp galectin 3 binding protein multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of LGALS3BP mRNA] CTD PMID:15190207 NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256
JBrowse link
G Lipe lipase E, hormone sensitive type decreases expression EXP Sulindac results in decreased expression of LIPE mRNA CTD PMID:24136188 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression EXP Sulindac results in increased expression of LITAF mRNA CTD PMID:24136188 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Lmf2 lipase maturation factor 2 decreases expression EXP Sulindac results in decreased expression of LMF2 mRNA CTD PMID:24136188 NCBI chr 7:120,418,343...120,422,825
Ensembl chr 7:120,418,345...120,422,823
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial decreases expression EXP Sulindac results in decreased expression of LONP1 mRNA CTD PMID:24136188 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771
JBrowse link
G Lox lysyl oxidase decreases expression ISO Sulindac analog results in decreased expression of LOX mRNA CTD PMID:18924134 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lrpprc leucine-rich pentatricopeptide repeat containing decreases expression EXP Sulindac results in decreased expression of LRPPRC mRNA CTD PMID:24136188 NCBI chr 6:9,859,816...9,942,294
Ensembl chr 6:9,859,867...9,942,293
JBrowse link
G Lsm10 LSM10, U7 small nuclear RNA associated increases expression EXP Sulindac results in increased expression of LSM10 mRNA CTD PMID:24136188 NCBI chr 5:138,365,983...138,375,856
Ensembl chr 5:138,373,119...138,377,505
JBrowse link
G Lsm12 LSM12 homolog increases expression EXP Sulindac results in increased expression of LSM12 mRNA CTD PMID:24136188 NCBI chr10:87,118,334...87,140,395
Ensembl chr10:87,118,416...87,140,396
JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated increases expression EXP Sulindac results in increased expression of LSM6 mRNA CTD PMID:24136188 NCBI chr19:29,098,254...29,112,858
Ensembl chr13:42,114,032...42,116,484
Ensembl chr19:42,114,032...42,116,484
JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression EXP Sulindac results in decreased expression of MACROH2A1 mRNA CTD PMID:24136188 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Maoa monoamine oxidase A decreases expression EXP Sulindac results in decreased expression of MAOA mRNA CTD PMID:24136188 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MAOB mRNA CTD PMID:20371263 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MAP3K8 mRNA CTD PMID:20371263 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 increases expression ISO Sulindac results in increased expression of MAP4K3 mRNA CTD PMID:11906190 NCBI chr 6:14,276,623...14,446,321
Ensembl chr 6:14,277,121...14,446,334
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK1 protein; Arsenic Trioxide promotes the reaction [Sulindac results in increased phosphorylation of MAPK1 protein]; Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Sulindac promotes the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]
[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MAPK1 mRNA
CTD PMID:12566304 PMID:18281123 PMID:18636201 PMID:20371263 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK3 protein; Arsenic Trioxide promotes the reaction [Sulindac results in increased phosphorylation of MAPK3 protein]; Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; Sulindac promotes the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein] CTD PMID:12566304 PMID:18281123 PMID:18636201 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
increases expression
ISO CDKN1A protein promotes the reaction [Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein]; MAPK8 affects the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; Sulindac promotes the reaction [IL24 protein results in increased phosphorylation of MAPK8 protein]; Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein; Sulindac results in increased phosphorylation of and results in increased activity of MAPK8 protein
Sulindac results in increased phosphorylation of MAPK8 protein
Sulindac results in increased expression of MAPK8 mRNA
CTD PMID:15713900 PMID:17292881 PMID:18281123 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mark3 microtubule affinity regulating kinase 3 decreases expression EXP Sulindac results in decreased expression of MARK3 mRNA CTD PMID:24136188 NCBI chr 6:130,626,612...130,716,245
Ensembl chr 6:130,627,482...130,716,647
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 decreases expression EXP Sulindac results in decreased expression of MBD2 mRNA CTD PMID:24136188 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 decreases expression EXP Sulindac results in decreased expression of MBD3 mRNA CTD PMID:24136188 NCBI chr 7:9,312,961...9,320,166
Ensembl chr 7:9,313,098...9,320,165
JBrowse link
G Me1 malic enzyme 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ME1 mRNA CTD PMID:20371263 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Med10 mediator complex subunit 10 increases expression EXP Sulindac results in increased expression of MED10 mRNA CTD PMID:24136188 NCBI chr 1:33,470,064...33,481,698
Ensembl chr 1:33,470,066...33,475,767
JBrowse link
G Med15 mediator complex subunit 15 increases expression ISO Sulindac results in increased expression of MED15 mRNA CTD PMID:11906190 NCBI chr11:83,280,722...83,356,006
Ensembl chr11:83,280,762...83,355,362
JBrowse link
G Mesd mesoderm development LRP chaperone decreases expression EXP Sulindac results in decreased expression of MESD mRNA CTD PMID:24136188 NCBI chr 1:137,866,707...137,879,999
Ensembl chr 1:137,874,242...137,879,999
JBrowse link
G Mettl23 methyltransferase 23, arginine increases expression EXP Sulindac results in increased expression of METTL23 mRNA CTD PMID:24136188 NCBI chr10:102,047,090...102,053,379
Ensembl chr10:102,047,314...102,051,977
JBrowse link
G Mfap3 microfibril associated protein 3 decreases expression EXP Sulindac results in decreased expression of MFAP3 mRNA CTD PMID:24136188 NCBI chr10:41,696,788...41,711,490
Ensembl chr10:41,696,771...41,710,406
JBrowse link
G Mff mitochondrial fission factor decreases expression EXP Sulindac results in decreased expression of MFF mRNA CTD PMID:24136188 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MGST2 mRNA CTD PMID:20371263 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MGST3 mRNA CTD PMID:20371263 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Miip migration and invasion inhibitory protein increases expression ISO Sulindac results in increased expression of MIIP mRNA CTD PMID:11906190 NCBI chr 5:158,292,510...158,299,533
Ensembl chr 5:158,292,511...158,299,694
JBrowse link
G Mllt6 MLLT6, PHD finger containing decreases expression EXP Sulindac results in decreased expression of MLLT6 mRNA CTD PMID:24136188 NCBI chr10:82,657,258...82,678,899
Ensembl chr10:82,656,872...82,676,073
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression EXP Sulindac results in decreased expression of MMP14 mRNA CTD PMID:24136188 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO Sulindac results in decreased expression of MMP7 mRNA; Sulindac results in decreased expression of MMP7 protein CTD PMID:18499699 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mogs mannosyl-oligosaccharide glucosidase decreases expression EXP Sulindac results in decreased expression of MOGS mRNA CTD PMID:24136188 NCBI chr 4:115,621,623...115,625,026
Ensembl chr 4:115,621,623...115,625,032
JBrowse link
G Mrpl1 mitochondrial ribosomal protein L1 decreases expression EXP Sulindac results in decreased expression of MRPL1 mRNA CTD PMID:24136188 NCBI chr14:13,300,522...13,359,654
Ensembl chr14:13,300,522...13,359,721
JBrowse link
G mrpl11 mitochondrial ribosomal protein L11 decreases expression EXP Sulindac results in decreased expression of MRPL11 mRNA CTD PMID:24136188 NCBI chr 1:202,264,419...202,267,288
Ensembl chr 1:202,264,471...202,267,756
JBrowse link
G Mrpl13 mitochondrial ribosomal protein L13 increases expression EXP Sulindac results in increased expression of MRPL13 mRNA CTD PMID:24136188 NCBI chr 7:86,951,541...86,973,147
Ensembl chr 7:86,951,541...86,973,577
JBrowse link
G Mrpl17 mitochondrial ribosomal protein L17 decreases expression EXP Sulindac results in decreased expression of MRPL17 mRNA CTD PMID:24136188 NCBI chr 1:160,162,181...160,163,870
Ensembl chr 1:160,158,807...160,163,815
JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 decreases expression EXP Sulindac results in decreased expression of MRPL20 mRNA CTD PMID:24136188 NCBI chr 5:166,408,962...166,413,492
Ensembl chr 5:166,408,962...166,413,492
JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 increases expression EXP Sulindac results in increased expression of MRPL22 mRNA CTD PMID:24136188 NCBI chr10:42,345,446...42,355,779
Ensembl chr10:42,342,776...42,355,779
JBrowse link
G Mrpl23 mitochondrial ribosomal protein L23 decreases expression EXP Sulindac results in decreased expression of MRPL23 mRNA CTD PMID:24136188 NCBI chr 1:197,687,452...197,695,222
Ensembl chr 1:197,687,347...197,695,222
JBrowse link
G Mrpl32 mitochondrial ribosomal protein L32 increases expression EXP Sulindac results in increased expression of MRPL32 mRNA CTD PMID:24136188 NCBI chr17:50,565,133...50,568,000
Ensembl chr17:50,565,055...50,568,010
JBrowse link
G Mrpl37 mitochondrial ribosomal protein L37 decreases expression EXP Sulindac results in decreased expression of MRPL37 mRNA CTD PMID:24136188 NCBI chr 5:121,827,892...121,846,187
Ensembl chr 5:121,829,111...121,846,176
JBrowse link
G Mrpl53 mitochondrial ribosomal protein L53 increases expression EXP Sulindac results in increased expression of MRPL53 mRNA CTD PMID:24136188 NCBI chr 4:115,615,329...115,616,219 JBrowse link
G Mrpl54 mitochondrial ribosomal protein L54 increases expression EXP Sulindac results in increased expression of MRPL54 mRNA CTD PMID:24136188 NCBI chr 7:8,452,801...8,455,321
Ensembl chr 7:8,452,716...8,455,321
JBrowse link
G Mrpl58 mitochondrial ribosomal protein L58 decreases expression EXP Sulindac results in decreased expression of MRPL58 mRNA CTD PMID:24136188 NCBI chr10:100,646,374...100,652,871
Ensembl chr10:100,646,216...100,652,871
JBrowse link
G Mrps14 mitochondrial ribosomal protein S14 decreases expression EXP Sulindac results in decreased expression of MRPS14 mRNA CTD PMID:24136188 NCBI chr13:72,429,168...72,434,915
Ensembl chr13:72,408,558...72,434,915
JBrowse link
G Mrps24 mitochondrial ribosomal protein S24 decreases expression EXP Sulindac results in decreased expression of MRPS24 mRNA CTD PMID:24136188 NCBI chr14:80,584,671...80,588,801
Ensembl chr14:80,584,673...80,588,871
JBrowse link
G Mrps31 mitochondrial ribosomal protein S31 decreases expression EXP Sulindac results in decreased expression of MRPS31 mRNA CTD PMID:24136188 NCBI chr16:69,601,349...69,621,609
Ensembl chr16:69,601,349...69,630,654
JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 increases expression EXP Sulindac results in increased expression of MRPS33 mRNA CTD PMID:24136188 NCBI chr 4:68,596,729...68,605,547
Ensembl chr 4:68,596,729...68,605,428
JBrowse link
G Mrps7 mitochondrial ribosomal protein S7 decreases expression EXP Sulindac results in decreased expression of MRPS7 mRNA CTD PMID:24136188 NCBI chr10:100,843,691...100,846,838
Ensembl chr10:100,843,356...100,847,129
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 increases expression EXP Sulindac results in increased expression of MRPS9 mRNA CTD PMID:24136188 NCBI chr 9:45,113,554...45,172,375
Ensembl chr 9:45,113,554...45,172,375
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression ISO Sulindac results in increased expression of MTHFD2 mRNA CTD PMID:11906190 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mtpn myotrophin increases expression EXP Sulindac results in increased expression of MTPN mRNA CTD PMID:24136188 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO Sulindac results in increased expression of MTTP mRNA CTD PMID:32535746 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Mug1 murinoglobulin 1 decreases expression EXP Sulindac results in decreased expression of MUG1 mRNA CTD PMID:24136188 NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
increases expression
ISO
EXP
CTNNB1 protein affects the reaction [Sulindac results in decreased expression of MYC protein]
Sulindac inhibits the reaction [Azoxymethane results in increased expression of MYC mRNA]; Sulindac inhibits the reaction [Azoxymethane results in increased expression of MYC protein]
Sulindac results in increased expression of MYC mRNA
CTD PMID:12189186 PMID:12414619 PMID:17292881 PMID:18291362 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mzf1 myeloid zinc finger 1 decreases expression EXP Sulindac results in decreased expression of MZF1 mRNA CTD PMID:24136188 NCBI chr 1:73,670,522...73,682,885
Ensembl chr 1:73,670,541...73,681,635
JBrowse link
G Naa35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit decreases expression EXP Sulindac results in decreased expression of NAA35 mRNA CTD PMID:24136188 NCBI chr17:5,034,360...5,086,456
Ensembl chr17:5,034,356...5,086,386
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression EXP Sulindac results in decreased expression of NAMPT mRNA CTD PMID:24136188 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression ISO Sulindac results in decreased expression of NAP1L1 mRNA CTD PMID:11507085 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Nat1 N-acetyltransferase 1 decreases expression ISO Sulindac results in decreased expression of NAT1 mRNA CTD PMID:11828994 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression
decreases expression
ISO
EXP
Sulindac results in increased expression of NDRG1 mRNA
Sulindac results in decreased expression of NDRG1 mRNA
CTD PMID:16273229 PMID:24136188 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 decreases expression ISO Sulindac results in decreased expression of NDST2 mRNA CTD PMID:11906190 NCBI chr15:3,563,515...3,573,801
Ensembl chr15:3,563,358...3,573,801
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 increases expression EXP Sulindac results in increased expression of NDUFA5 mRNA CTD PMID:24136188 NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:52,995,546...53,005,598
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 increases expression EXP Sulindac results in increased expression of NDUFV3 mRNA CTD PMID:24136188 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074
JBrowse link
G Nek7 NIMA-related kinase 7 decreases expression EXP Sulindac results in decreased expression of NEK7 mRNA CTD PMID:24136188 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
JBrowse link
G Neu1 neuraminidase 1 increases expression ISO Sulindac results in increased expression of NEU1 mRNA CTD PMID:11906190 NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO
EXP
Sulindac results in increased expression of NFE2L1 mRNA CTD PMID:11906190 PMID:24136188 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfib nuclear factor I/B multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of NFIB mRNA CTD PMID:20371263 NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO Sulindac results in increased expression of NFIL3 mRNA CTD PMID:11906190 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases activity
ISO Acetylcysteine inhibits the reaction [Sulindac analog results in decreased activity of NFKB1 protein]; Sulindac inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Sulindac inhibits the reaction [TNF protein results in increased activity of NFKB1 protein] CTD PMID:15489888 PMID:18922898 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation
ISO
EXP
[[Sulindac co-treated with arsenic trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein] which affects the localization of RELA protein; [Sulindac co-treated with arsenic trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein; Sulindac inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Sulindac results in increased degradation of and results in decreased expression of NFKBIA protein
[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of NFKBIA mRNA
Sulindac results in decreased phosphorylation of NFKBIA protein
CTD PMID:11591705 PMID:15489888 PMID:18059344 PMID:18575716 PMID:20371263 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfu1 NFU1 iron-sulfur cluster scaffold decreases expression EXP Sulindac results in decreased expression of NFU1 mRNA CTD PMID:24136188 NCBI chr 4:119,458,981...119,480,162
Ensembl chr 4:119,459,061...119,480,373
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 increases expression ISO Sulindac results in increased expression of NPC1 mRNA CTD PMID:11906190 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
JBrowse link
G Nphp1 nephrocystin 1 increases expression EXP Sulindac results in increased expression of NPHP1 mRNA CTD PMID:24136188 NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression
ISO Sulindac results in increased activity of NQO1 protein
Sulindac results in increased expression of NQO1 mRNA
CTD PMID:11093808 PMID:17985343 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor decreases expression EXP Sulindac results in decreased expression of NSMF mRNA CTD PMID:24136188 NCBI chr 3:7,861,846...7,870,615
Ensembl chr 3:7,861,872...7,870,614
JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 increases expression EXP Sulindac results in increased expression of NUDT16L1 mRNA CTD PMID:24136188 NCBI chr10:10,636,174...10,638,090
Ensembl chr10:10,636,174...10,688,370
JBrowse link
G Numb NUMB, endocytic adaptor protein increases expression EXP Sulindac results in increased expression of NUMB mRNA CTD PMID:24136188 NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354
JBrowse link
G Nup37 nucleoporin 37 increases expression EXP Sulindac results in increased expression of NUP37 mRNA CTD PMID:24136188 NCBI chr 7:22,556,544...22,609,622
Ensembl chr 7:22,573,764...22,609,616
JBrowse link
G Nupr2 nuclear protein 2, transcriptional regulator increases expression EXP Sulindac results in increased expression of NUPR2 mRNA CTD PMID:24136188 NCBI chr12:26,800,123...26,803,228
Ensembl chr12:26,799,800...26,803,304
JBrowse link
G Orc4 origin recognition complex, subunit 4 decreases expression ISO Sulindac results in decreased expression of ORC4 mRNA CTD PMID:11906190 NCBI chr 3:33,290,844...33,334,022
Ensembl chr 3:33,294,355...33,333,824
JBrowse link
G Osbpl9 oxysterol binding protein-like 9 decreases expression EXP Sulindac results in decreased expression of OSBPL9 mRNA CTD PMID:24136188 NCBI chr 5:123,819,106...123,962,213
Ensembl chr 5:123,819,104...123,962,196
JBrowse link
G Ostf1 osteoclast stimulating factor 1 increases expression ISO Sulindac results in increased expression of OSTF1 mRNA CTD PMID:11906190 NCBI chr 1:216,002,037...216,049,226
Ensembl chr 1:216,002,044...216,049,221
JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 increases expression EXP Sulindac results in increased expression of OSTM1 mRNA CTD PMID:24136188 NCBI chr20:46,071,657...46,187,049
Ensembl chr20:46,153,075...46,187,023
JBrowse link
G Otud1 OTU deubiquitinase 1 increases expression ISO Sulindac results in increased expression of OTUD1 mRNA CTD PMID:11906190 NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression ISO Sulindac results in decreased expression of P4HB mRNA CTD PMID:32535746 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 increases expression EXP Sulindac results in increased expression of PACSIN3 mRNA CTD PMID:24136188 NCBI chr 3:77,227,187...77,235,820
Ensembl chr 3:77,222,710...77,235,811
JBrowse link
G Pak6 p21 (RAC1) activated kinase 6 decreases expression EXP Sulindac results in decreased expression of PAK6 mRNA CTD PMID:24136188 NCBI chr 3:105,638,248...105,674,399
Ensembl chr 3:105,638,653...105,672,975
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases activity
ISO [Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]; Sulindac promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]
Sulindac results in increased activity of PARP1 protein
CTD PMID:15713900 PMID:18281123 PMID:21882223 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 decreases expression EXP Sulindac results in decreased expression of PARP14 mRNA CTD PMID:24136188 NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916
JBrowse link
G Pbrm1 polybromo 1 decreases expression EXP Sulindac results in decreased expression of PBRM1 mRNA CTD PMID:24136188 NCBI chr16:6,213,507...6,312,895
Ensembl chr16:6,213,300...6,311,780
JBrowse link
G Pcbp1 poly(rC) binding protein 1 increases expression EXP Sulindac results in increased expression of PCBP1 mRNA CTD PMID:24136188 NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500
JBrowse link
G Pcdh17 protocadherin 17 decreases expression ISO Sulindac results in decreased expression of PCDH17 mRNA CTD PMID:11906190 NCBI chr15:60,222,088...60,316,172
Ensembl chr15:60,222,004...60,313,999
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO Sulindac results in increased expression of PCK2 mRNA CTD PMID:11906190 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions
ISO
EXP
Sulindac results in decreased expression of PCNA protein
epigallocatechin gallate promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein]]; kaempferol promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein]]; Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein]
CTD PMID:15020200 PMID:29999212 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of PDGFA mRNA CTD PMID:20371263 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdlim7 PDZ and LIM domain 7 increases expression ISO Sulindac results in increased expression of PDLIM7 mRNA CTD PMID:11906190 NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811
JBrowse link
G Per1 period circadian regulator 1 decreases expression EXP Sulindac results in decreased expression of PER1 mRNA CTD PMID:24136188 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 increases expression EXP Sulindac results in increased expression of PEX2 mRNA CTD PMID:24136188 NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404
JBrowse link
G Pfdn6 prefoldin subunit 6 increases expression EXP Sulindac results in increased expression of PFDN6 mRNA CTD PMID:24136188 NCBI chr20:4,945,959...4,947,433
Ensembl chr20:4,945,959...4,947,433
JBrowse link
G Pgap2 post-GPI attachment to proteins 2 decreases expression EXP Sulindac results in decreased expression of PGAP2 mRNA CTD PMID:24136188 NCBI chr 1:156,591,540...156,618,116
Ensembl chr 1:156,591,615...156,618,114
JBrowse link
G Pi4k2b phosphatidylinositol 4-kinase type 2 beta increases expression EXP Sulindac results in increased expression of PI4K2B mRNA CTD PMID:24136188 NCBI chr14:58,221,790...58,248,716
Ensembl chr14:58,220,437...58,248,673
JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha increases expression EXP Sulindac results in increased expression of PI4KA mRNA CTD PMID:24136188 NCBI chr11:83,609,148...83,726,876
Ensembl chr11:83,609,069...83,724,080
JBrowse link
G Pigc phosphatidylinositol glycan anchor biosynthesis, class C increases expression EXP Sulindac results in increased expression of PIGC mRNA CTD PMID:24136188 NCBI chr13:74,343,619...74,346,148
Ensembl chr13:74,296,854...74,346,211
JBrowse link
G Pigy phosphatidylinositol glycan anchor biosynthesis, class Y increases expression EXP Sulindac results in increased expression of PIGY mRNA CTD PMID:24136188 NCBI chr 8:20,689,621...20,691,863
Ensembl chr 8:20,689,502...20,692,585
JBrowse link
G Pisd phosphatidylserine decarboxylase decreases expression EXP Sulindac results in decreased expression of PISD mRNA CTD PMID:24136188 NCBI chr14:77,941,927...77,991,021
Ensembl chr14:77,941,948...77,991,003
JBrowse link
G Pithd1 PITH domain containing 1 increases expression EXP Sulindac results in increased expression of PITHD1 mRNA CTD PMID:24136188 NCBI chr 5:148,205,995...148,216,490
Ensembl chr 5:148,205,998...148,217,080
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting increases expression ISO Sulindac results in increased expression of PKD1 mRNA CTD PMID:11906190 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions
decreases expression
ISO Sulindac inhibits the reaction [PLA2G4A gene mutant form results in decreased expression of SOD1 protein]
Sulindac results in decreased expression of PLA2G4A mRNA
CTD PMID:10706128 PMID:15816863 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of PLAT mRNA CTD PMID:12628509 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of PLCG1 mRNA CTD PMID:20371263 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plec plectin increases expression EXP Sulindac results in increased expression of PLEC mRNA CTD PMID:24136188 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
JBrowse link
G Plekhb2 pleckstrin homology domain containing B2 decreases expression EXP Sulindac results in decreased expression of PLEKHB2 mRNA CTD PMID:24136188 NCBI chr 9:37,049,580...37,082,231
Ensembl chr 9:37,038,751...37,082,231
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 increases expression ISO Sulindac results in increased expression of PLEKHF1 mRNA CTD PMID:11906190 NCBI chr 1:90,908,304...90,915,862
Ensembl chr 1:90,904,742...90,915,820
JBrowse link
G Plxna3 plexin A3 increases expression ISO Sulindac results in increased expression of PLXNA3 mRNA CTD PMID:11906190 NCBI chr  X:152,115,699...152,131,608
Ensembl chr  X:152,115,819...152,131,603
JBrowse link
G Pml PML nuclear body scaffold increases expression ISO Sulindac results in increased expression of PML mRNA CTD PMID:16273229 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pole4 DNA polymerase epsilon 4, accessory subunit decreases expression EXP Sulindac results in decreased expression of POLE4 mRNA CTD PMID:24136188 NCBI chr 4:115,165,285...115,171,097
Ensembl chr 4:115,165,285...115,171,097
JBrowse link
G Polr2c RNA polymerase II subunit C decreases expression EXP Sulindac results in decreased expression of POLR2C mRNA CTD PMID:24136188 NCBI chr19:10,158,153...10,164,935
Ensembl chr19:10,157,823...10,164,945
JBrowse link
G Pomp proteasome maturation protein decreases expression EXP Sulindac results in decreased expression of POMP mRNA CTD PMID:24136188 NCBI chr12:7,162,098...7,174,737
Ensembl chr12:7,160,714...7,174,715
JBrowse link
G Pon3 paraoxonase 3 decreases expression EXP Sulindac results in decreased expression of PON3 mRNA CTD PMID:24136188 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression
affects response to substance
ISO Sulindac results in increased expression of PPARD protein
PPARD protein affects the susceptibility to Sulindac
CTD