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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:olivetol
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Accession:CHEBI:66960 term browser browse the term
Definition:A member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group.
Synonyms:exact_synonym: 5-pentylbenzene-1,3-diol
 related_synonym: 3,5-dihydroxyamylbenzene;   5-(1-pentyl)resorcinol;   5-n-amylresorcinol;   5-n-pentylresorcinol;   5-pentyl-1,3-benzenediol;   5-pentylresorcinol;   Formula=C11H16O2;   InChI=1S/C11H16O2/c1-2-3-4-5-9-6-10(12)8-11(13)7-9/h6-8,12-13H,2-5H2,1H3;   InChIKey=IRMPFYJSHJGOPE-UHFFFAOYSA-N;   SMILES=CCCCCc1cc(O)cc(O)c1
 xref: AGR:IND43618541;   CAS:500-66-3
 xref_mesh: MESH:C016630
 xref: MetaCyc:CPD-11505;   PMID:19454282;   PMID:22802619;   PMID:6512535;   Reaxys:908277;   Wikipedia:Olivetol


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olivetol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression		 ISO olivetol results in decreased activity of CYP1A1 protein
olivetol results in increased expression of CYP1A1 mRNA		 CTD PMID:24667653 PMID:26187180 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO olivetol results in decreased activity of CYP2D6 protein CTD PMID:21821735 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
cannabidiolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases expression ISO cannabidiolic acid results in increased expression of ACOX1 mRNA CTD PMID:30611848 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 increases expression ISO cannabidiolic acid results in increased expression of BHLHE41 mRNA CTD PMID:25242400 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions
increases expression		 ISO cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]
cannabidiolic acid results in increased expression of CEBPA mRNA		 CTD PMID:30611848 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO cannabidiolic acid results in increased expression of CPT1A mRNA CTD PMID:30611848 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression		 ISO cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]
cannabidiolic acid results in increased expression of FABP4 mRNA		 CTD PMID:30611848 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO cannabidiolic acid results in decreased expression of FOS mRNA CTD PMID:27530354 PMID:30496661 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases expression ISO cannabidiolic acid results in increased expression of HTR1A mRNA CTD PMID:27530354 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO cannabidiolic acid results in decreased expression of ID1 mRNA CTD PMID:25242400 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO cannabidiolic acid results in decreased expression of IGF1 protein CTD PMID:33010341 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]; cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA] CTD PMID:30611848 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases expression		 ISO cannabidiolic acid binds to and results in increased activity of PPARA protein
cannabidiolic acid results in increased expression of PPARA mRNA		 CTD PMID:30611848 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
decreases expression		 ISO cannabidiolic acid results in increased expression of PPARG mRNA
cannabidiolic acid binds to and results in increased activity of PPARG protein; cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]
cannabidiolic acid results in decreased expression of PPARG protein		 CTD PMID:28853159 PMID:30611848 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 ISO cannabidiolic acid results in decreased expression of PTGS2 mRNA
cannabidiolic acid inhibits the reaction [GW 501516 results in increased expression of PTGS2 mRNA]; cannabidiolic acid promotes the reaction [GSK0660 results in decreased expression of PTGS2 mRNA]		 CTD PMID:25242400 PMID:27530354 PMID:30496661 PMID:32238697 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO cannabidiolic acid results in increased activity of TRPA1 protein CTD PMID:31096838 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 decreases expression ISO cannabidiolic acid results in decreased expression of TRPM8 mRNA CTD PMID:27530354 NCBI chr 9:88,897,039...88,990,167
Ensembl chr 9:88,903,880...88,988,552 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity
multiple interactions		 ISO cannabidiolic acid results in increased activity of TRPV1 protein
[cannabidiolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium		 CTD PMID:31096838 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 multiple interactions
increases expression		 ISO [cannabidiolic acid results in increased activity of TRPV2 protein] which results in increased uptake of Calcium
cannabidiolic acid results in increased expression of TRPV2 mRNA		 CTD PMID:27530354 PMID:31096838 NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260 		JBrowse link
cannabigerolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases expression ISO cannabigerolic acid results in increased expression of ACOX1 mRNA CTD PMID:30611848 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO cannabigerolic acid results in increased expression of CPT1A mRNA CTD PMID:30611848 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression		 ISO cannabigerolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]
cannabigerolic acid results in increased expression of FABP4 mRNA		 CTD PMID:30611848 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO cannabigerolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]; cannabigerolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA] CTD PMID:30611848 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
multiple interactions		 ISO cannabigerolic acid results in increased expression of PPARA mRNA
cannabigerolic acid binds to and results in increased activity of PPARA protein		 CTD PMID:30611848 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
decreases expression		 ISO cannabigerolic acid results in increased expression of PPARG mRNA
cannabigerolic acid binds to and results in increased activity of PPARG protein
cannabigerolic acid binds to and results in increased activity of PPARG protein; cannabigerolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]
cannabigerolic acid results in decreased expression of PPARG protein		 CTD PMID:28853159 PMID:30611848 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity		 ISO [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium CTD PMID:31096838 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 affects activity EXP cannabigerolic acid affects the activity of TRPV3 protein CTD PMID:21726418 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        biochemical role 19671
          metabolite 19631
            lichen metabolite 89
              olivetol 20
                olivetolic acid + 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                organic aromatic compound 19451
                                  phenols 18642
                                    benzenediols 8998
                                      resorcinols 7243
                                        olivetol 20
                                          olivetolic acid + 18
paths to the root