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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
decreases activity increases expression |
ISO |
olivetol results in decreased activity of CYP1A1 protein olivetol results in increased expression of CYP1A1 mRNA |
CTD |
PMID:24667653 PMID:26187180 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
decreases activity |
ISO |
olivetol results in decreased activity of CYP2D6 protein |
CTD |
PMID:21821735 |
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NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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G |
Acox1 |
acyl-CoA oxidase 1 |
increases expression |
ISO |
cannabidiolic acid results in increased expression of ACOX1 mRNA |
CTD |
PMID:30611848 |
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NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
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G |
Bhlhe41 |
basic helix-loop-helix family, member e41 |
increases expression |
ISO |
cannabidiolic acid results in increased expression of BHLHE41 mRNA |
CTD |
PMID:25242400 |
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NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions increases expression |
ISO |
cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA] cannabidiolic acid results in increased expression of CEBPA mRNA |
CTD |
PMID:30611848 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression |
ISO |
cannabidiolic acid results in increased expression of CPT1A mRNA |
CTD |
PMID:30611848 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions increases expression |
ISO |
cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA] cannabidiolic acid results in increased expression of FABP4 mRNA |
CTD |
PMID:30611848 |
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NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
cannabidiolic acid results in decreased expression of FOS mRNA |
CTD |
PMID:27530354 PMID:30496661 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Htr1a |
5-hydroxytryptamine receptor 1A |
increases expression |
ISO |
cannabidiolic acid results in increased expression of HTR1A mRNA |
CTD |
PMID:27530354 |
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NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
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G |
Id1 |
inhibitor of DNA binding 1, HLH protein |
decreases expression |
ISO |
cannabidiolic acid results in decreased expression of ID1 mRNA |
CTD |
PMID:25242400 |
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NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Igf1 |
insulin-like growth factor 1 |
decreases expression |
ISO |
cannabidiolic acid results in decreased expression of IGF1 protein |
CTD |
PMID:33010341 |
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]; cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA] |
CTD |
PMID:30611848 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions increases expression |
ISO |
cannabidiolic acid binds to and results in increased activity of PPARA protein cannabidiolic acid results in increased expression of PPARA mRNA |
CTD |
PMID:30611848 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression multiple interactions decreases expression |
ISO |
cannabidiolic acid results in increased expression of PPARG mRNA cannabidiolic acid binds to and results in increased activity of PPARG protein; cannabidiolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA] cannabidiolic acid results in decreased expression of PPARG protein |
CTD |
PMID:28853159 PMID:30611848 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression multiple interactions |
ISO |
cannabidiolic acid results in decreased expression of PTGS2 mRNA cannabidiolic acid inhibits the reaction [GW 501516 results in increased expression of PTGS2 mRNA]; cannabidiolic acid promotes the reaction [GSK0660 results in decreased expression of PTGS2 mRNA] |
CTD |
PMID:25242400 PMID:27530354 PMID:30496661 PMID:32238697 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
increases activity |
ISO |
cannabidiolic acid results in increased activity of TRPA1 protein |
CTD |
PMID:31096838 |
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NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
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G |
Trpm8 |
transient receptor potential cation channel, subfamily M, member 8 |
decreases expression |
ISO |
cannabidiolic acid results in decreased expression of TRPM8 mRNA |
CTD |
PMID:27530354 |
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NCBI chr 9:88,897,039...88,990,167
Ensembl chr 9:88,903,880...88,988,552
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
increases activity multiple interactions |
ISO |
cannabidiolic acid results in increased activity of TRPV1 protein [cannabidiolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium |
CTD |
PMID:31096838 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Trpv2 |
transient receptor potential cation channel, subfamily V, member 2 |
multiple interactions increases expression |
ISO |
[cannabidiolic acid results in increased activity of TRPV2 protein] which results in increased uptake of Calcium cannabidiolic acid results in increased expression of TRPV2 mRNA |
CTD |
PMID:27530354 PMID:31096838 |
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NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260
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G |
Acox1 |
acyl-CoA oxidase 1 |
increases expression |
ISO |
cannabigerolic acid results in increased expression of ACOX1 mRNA |
CTD |
PMID:30611848 |
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NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression |
ISO |
cannabigerolic acid results in increased expression of CPT1A mRNA |
CTD |
PMID:30611848 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions increases expression |
ISO |
cannabigerolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA] cannabigerolic acid results in increased expression of FABP4 mRNA |
CTD |
PMID:30611848 |
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NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
cannabigerolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]; cannabigerolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA] |
CTD |
PMID:30611848 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases expression multiple interactions |
ISO |
cannabigerolic acid results in increased expression of PPARA mRNA cannabigerolic acid binds to and results in increased activity of PPARA protein |
CTD |
PMID:30611848 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression multiple interactions decreases expression |
ISO |
cannabigerolic acid results in increased expression of PPARG mRNA cannabigerolic acid binds to and results in increased activity of PPARG protein cannabigerolic acid binds to and results in increased activity of PPARG protein; cannabigerolic acid promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA] cannabigerolic acid results in decreased expression of PPARG protein |
CTD |
PMID:28853159 PMID:30611848 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions increases activity |
ISO |
[cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium |
CTD |
PMID:31096838 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Trpv3 |
transient receptor potential cation channel, subfamily V, member 3 |
affects activity |
EXP |
cannabigerolic acid affects the activity of TRPV3 protein |
CTD |
PMID:21726418 |
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NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
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