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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:olivetolic acid
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Accession:CHEBI:66955 term browser browse the term
Definition:A member of the class of benzoic acids that is salicylic acid in which the hydrogens ortho- and para- to the carboxy group are replaced by a pentyl and a hydroxy group, respectively.
Synonyms:exact_synonym: 2,4-dihydroxy-6-pentylbenzoic acid
 related_synonym: 6-pentyl-beta-resorcylic acid;   Formula=C12H16O4;   InChI=1S/C12H16O4/c1-2-3-4-5-8-6-9(13)7-10(14)11(8)12(15)16/h6-7,13-14H,2-5H2,1H3,(H,15,16);   InChIKey=SXFKFRRXJUJGSS-UHFFFAOYSA-N;   SMILES=CCCCCc1cc(O)cc(O)c1C(O)=O;   allazetolcarboxylic acid;   olivetolcarboxylic acid
 xref: CAS:491-72-5;   MetaCyc:CPD-7165;   PMID:19454282;   PMID:22802619;   Reaxys:2807862
 cyclic_relationship: is_conjugate_acid_of CHEBI:66950


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cannabidiolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe41 basic helix-loop-helix family, member e41 increases expression ISO cannabidiolic acid results in increased expression of BHLHE41 mRNA CTD PMID:25242400 NCBI chr 6:145,858,243...145,865,420
Ensembl chr 6:145,858,243...145,865,558
JBrowse link
G Fos FBJ osteosarcoma oncogene decreases expression ISO cannabidiolic acid results in decreased expression of FOS mRNA CTD PMID:27530354 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A increases expression ISO cannabidiolic acid results in increased expression of HTR1A mRNA CTD PMID:27530354 NCBI chr13:105,443,693...105,448,133
Ensembl chr13:105,443,639...105,448,122
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO cannabidiolic acid results in decreased expression of ID1 mRNA CTD PMID:25242400 NCBI chr 2:152,736,251...152,737,410
Ensembl chr 2:152,736,251...152,737,410
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression
increases expression
ISO cannabidiolic acid results in decreased expression of PPARG protein
cannabidiolic acid results in increased expression of PPARG mRNA
CTD PMID:28853159 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO cannabidiolic acid results in decreased expression of PTGS2 mRNA
cannabidiolic acid inhibits the reaction [GW 501516 results in increased expression of PTGS2 mRNA]; cannabidiolic acid promotes the reaction [GSK0660 results in decreased expression of PTGS2 mRNA]
CTD PMID:25242400 PMID:27530354 PMID:32238697 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO cannabidiolic acid results in increased activity of TRPA1 protein CTD PMID:31096838 NCBI chr 1:14,872,644...14,918,862
Ensembl chr 1:14,872,648...14,918,862
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 decreases expression ISO cannabidiolic acid results in decreased expression of TRPM8 mRNA CTD PMID:27530354 NCBI chr 1:88,306,735...88,388,853
Ensembl chr 1:88,277,661...88,389,293
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity
multiple interactions
ISO cannabidiolic acid results in increased activity of TRPV1 protein
[cannabidiolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium
CTD PMID:31096838 NCBI chr11:73,234,149...73,261,322
Ensembl chr11:73,234,292...73,261,242
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 increases expression
multiple interactions
ISO cannabidiolic acid results in increased expression of TRPV2 mRNA
[cannabidiolic acid results in increased activity of TRPV2 protein] which results in increased uptake of Calcium
CTD PMID:27530354 PMID:31096838 NCBI chr11:62,574,486...62,600,305
Ensembl chr11:62,574,486...62,600,515
JBrowse link
cannabigerolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator activated receptor gamma increases expression
decreases expression
ISO cannabigerolic acid results in increased expression of PPARG mRNA
cannabigerolic acid results in decreased expression of PPARG protein
CTD PMID:28853159 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
ISO [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium CTD PMID:31096838 NCBI chr11:73,234,149...73,261,322
Ensembl chr11:73,234,292...73,261,242
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21552
    role 21530
      biological role 21528
        biochemical role 20696
          metabolite 20647
            olivetolic acid 10
              cannabidiolic acid 10
              cannabigerolic acid 2
              cannabinerolic acid 0
              cytonic acid A 0
              cytonic acid B 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21552
    subatomic particle 21537
      composite particle 21537
        hadron 21537
          baryon 21537
            nucleon 21537
              atomic nucleus 21537
                atom 21537
                  main group element atom 21442
                    p-block element atom 21442
                      carbon group element atom 21235
                        carbon atom 21133
                          organic molecular entity 21133
                            organic group 19572
                              organic divalent group 19562
                                organodiyl group 19562
                                  carbonyl group 19543
                                    carbonyl compound 19543
                                      carboxylic acid 19118
                                        aromatic carboxylic acid 11082
                                          benzoic acids 11052
                                            olivetolic acid 10
                                              cannabidiolic acid 10
                                              cannabigerolic acid 2
                                              cannabinerolic acid 0
                                              cytonic acid A 0
                                              cytonic acid B 0
paths to the root