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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:o-toluidine
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Accession:CHEBI:66892 term browser browse the term
Definition:An aminotoluene in which the amino substituent is ortho to the methyl group.
Synonyms:exact_synonym: 2-methylaniline
 related_synonym: 1-Amino-2-methylbenzene;   1-Methyl-2-aminobenzene;   2-Aminotoluene;   2-Methylbenzamine;   2-Methylbenzenamine;   2-Toluidine;   Formula=C7H9N;   InChI=1S/C7H9N/c1-6-4-2-3-5-7(6)8/h2-5H,8H2,1H3;   InChIKey=RNVCVTLRINQCPJ-UHFFFAOYSA-N;   SMILES=Cc1ccccc1N;   o-Aminotoluene;   o-Methylaniline;   o-Methylbenzenamine;   o-Tolylamine
 xref: CAS:95-53-4;   HMDB:HMDB0041965;   KEGG:C14403
 xref_mesh: MESH:C023622
 xref: PMID:21117897;   PMID:21320752;   PMID:21701861;   PMID:22004833;   PMID:22574454;   PMID:22708702;   PMID:22799188;   Reaxys:741981



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o-toluidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpo myeloperoxidase multiple interactions ISO [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 2-toluidine] which results in increased expression of MPO protein modified form; [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 2-toluidine CTD PMID:20199096 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20059
    role 20009
      biological role 20008
        aetiopathogenetic role 19264
          carcinogenic agent 18536
            o-toluidine 1
              5-nitro-o-toluidine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    main group molecular entity 19956
                      s-block molecular entity 19744
                        hydrogen molecular entity 19736
                          hydrides 19102
                            inorganic hydride 17893
                              pnictogen hydride 17876
                                nitrogen hydride 17766
                                  azane 17518
                                    ammonia 17517
                                      organic amino compound 17517
                                        aromatic amine 14924
                                          anilines 13985
                                            substituted aniline 13663
                                              aminotoluene 603
                                                o-toluidine 1
                                                  5-nitro-o-toluidine 0
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