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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:C4-dicarboxylic acid
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Accession:CHEBI:66873 term browser browse the term
Definition:Any dicarboxylic acid that contains four carbon atoms.
Synonyms:related_synonym: C4-dicarboxylic acids
 cyclic_relationship: is_conjugate_acid_of CHEBI:61336


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Ac-Asp-Glu term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Folh1 folate hydrolase 1 affects binding
multiple interactions
ISO isospaglumic acid binds to FOLH1 protein
[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein]
CTD PMID:24508213 NCBI chr 7:86,716,525...86,776,053
Ensembl chr 7:86,718,977...86,775,943
JBrowse link
artesunate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin, alpha 2, smooth muscle, aorta multiple interactions
decreases expression
EXP
ISO
Artesunate inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
Artesunate results in decreased expression of ACTA2 mRNA; Artesunate results in decreased expression of ACTA2 protein
Deferoxamine inhibits the reaction [Artesunate results in decreased expression of ACTA2 mRNA]
CTD PMID:30551460 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 affects localization ISO artesunate affects the localization of AIFM1 protein CTD PMID:24704559 NCBI chr  X:48,474,944...48,513,563
Ensembl chr  X:48,474,944...48,513,563
JBrowse link
G Ar androgen receptor multiple interactions ISO artesunate binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Atg12 autophagy related 12 increases expression ISO Artesunate results in increased expression of ATG12 mRNA CTD PMID:30551460 NCBI chr18:46,732,417...46,741,724
Ensembl chr18:46,730,144...46,741,580
JBrowse link
G Atg3 autophagy related 3 increases expression ISO Artesunate results in increased expression of ATG3 mRNA CTD PMID:30551460 NCBI chr16:45,158,829...45,188,538
Ensembl chr16:45,158,785...45,188,538
JBrowse link
G Atg5 autophagy related 5 increases expression ISO Artesunate results in increased expression of ATG5 mRNA CTD PMID:30551460 NCBI chr10:44,268,322...44,364,299
Ensembl chr10:44,268,358...44,364,291
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
ISO artesunate results in increased expression of BAX protein
[1,2-Dimethylhydrazine co-treated with artesunate] results in increased expression of BAX protein
CTD PMID:24704559 PMID:29031619 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
ISO artesunate results in decreased expression of BCL2 protein
[1,2-Dimethylhydrazine co-treated with artesunate] results in decreased expression of BCL2 protein
CTD PMID:24704559 PMID:29031619 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bst1 bone marrow stromal cell antigen 1 increases response to substance ISO BST1 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr 5:43,818,880...43,843,468
Ensembl chr 5:43,818,885...43,843,986
JBrowse link
G Casp3 caspase 3 increases activity ISO artesunate results in increased activity of CASP3 protein CTD PMID:19513562 PMID:24704559 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 affects expression ISO artesunate affects the expression of CASP9 protein CTD PMID:24704559 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase increases expression
decreases response to substance
ISO artesunate results in increased expression of CAT protein
CAT protein results in decreased susceptibility to artesunate
CTD PMID:19513562 PMID:20144594 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cct2 chaperonin containing Tcp1, subunit 2 (beta) decreases response to substance ISO CCT2 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr10:117,050,997...117,063,852
Ensembl chr10:117,051,001...117,063,814
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation
multiple interactions
ISO Artesunate results in increased phosphorylation of CHEK1 protein
APOBEC3C protein promotes the reaction [Artesunate results in increased phosphorylation of CHEK1 protein]
CTD PMID:31664825 NCBI chr 9:36,708,482...36,726,658
Ensembl chr 9:36,708,482...36,727,065
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases phosphorylation
ISO APOBEC3C protein promotes the reaction [Artesunate results in increased phosphorylation of CHEK2 protein] CTD PMID:31664825 NCBI chr 5:110,839,800...110,874,140
Ensembl chr 5:110,839,979...110,874,145
JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 increases response to substance ISO CLIP4 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr17:71,769,674...71,864,210
Ensembl chr17:71,768,473...71,864,273
JBrowse link
G Coq8a coenzyme Q8A decreases response to substance ISO COQ8A mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 1:180,165,238...180,196,020
Ensembl chr 1:180,165,238...180,199,602
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 multiple interactions ISO artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTNNB1 protein] CTD PMID:29031619 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 affects metabolic processing ISO CYP2A6 protein affects the metabolism of Artesunate CTD PMID:12920490 NCBI chr 7:26,835,339...26,843,264
Ensembl chr 7:26,835,305...26,843,548
JBrowse link
G Dbh dopamine beta hydroxylase increases response to substance ISO DBH mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr 2:27,165,507...27,183,204
Ensembl chr 2:27,165,233...27,183,200
JBrowse link
G Des desmin decreases expression
multiple interactions
ISO Artesunate results in decreased expression of DES mRNA; Artesunate results in decreased expression of DES protein
Deferoxamine inhibits the reaction [Artesunate results in decreased expression of DES mRNA]
CTD PMID:30551460 NCBI chr 1:75,360,292...75,368,579
Ensembl chr 1:75,360,329...75,368,579
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO artesunate binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) increases expression ISO artesunate results in increased expression of FAS protein CTD PMID:19513562 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Flna filamin, alpha increases response to substance ISO FLNA mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr  X:74,223,461...74,249,854
Ensembl chr  X:74,223,461...74,249,820
JBrowse link
G Fn1 fibronectin 1 multiple interactions
decreases expression
ISO Deferoxamine inhibits the reaction [Artesunate results in decreased expression of FN1 mRNA]
Artesunate results in decreased expression of FN1 mRNA; Artesunate results in decreased expression of FN1 protein
CTD PMID:30551460 NCBI chr 1:71,585,473...71,653,280
Ensembl chr 1:71,585,520...71,653,200
JBrowse link
G Fth1 ferritin heavy polypeptide 1 decreases expression
multiple interactions
ISO Artesunate results in decreased expression of FTH1 mRNA; Artesunate results in decreased expression of FTH1 protein
Chloroquine inhibits the reaction [Artesunate results in decreased expression of FTH1 mRNA]
CTD PMID:30551460 NCBI chr19:9,980,600...9,985,111
Ensembl chr19:9,980,598...9,985,098
JBrowse link
G Fzd7 frizzled class receptor 7 increases response to substance ISO FZD7 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr 1:59,482,147...59,486,955
Ensembl chr 1:59,482,424...59,486,955
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects response to substance
decreases response to substance
ISO GCLC mRNA affects the susceptibility to artesunate
GCLC mRNA results in decreased susceptibility to artesunate
CTD PMID:15796179 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit decreases response to substance ISO GCLM mRNA results in decreased susceptibility to artesunate CTD PMID:15796179 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions
decreases activity
EXP
ISO
Artesunate inhibits the reaction [Carbon Tetrachloride results in increased expression of GPX4 protein]
Artesunate results in decreased activity of GPX4 protein
CTD PMID:30551460 NCBI chr10:80,047,166...80,056,439
Ensembl chr10:80,047,166...80,056,439
JBrowse link
G Gstm4 glutathione S-transferase, mu 4 affects response to substance ISO GSTM4 mRNA affects the susceptibility to artesunate CTD PMID:15796179 NCBI chr 3:108,030,571...108,045,179
Ensembl chr 3:108,040,408...108,044,894
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 decreases expression ISO artesunate results in decreased expression of GSTP1 protein CTD PMID:19513562 NCBI chr19:4,035,411...4,037,912
Ensembl chr19:4,035,407...4,037,985
JBrowse link
G Gstz1 glutathione transferase zeta 1 (maleylacetoacetate isomerase) affects response to substance ISO GSTZ1 mRNA affects the susceptibility to artesunate CTD PMID:15796179 NCBI chr12:87,147,161...87,164,723
Ensembl chr12:87,147,165...87,164,723
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO artesunate inhibits the reaction [Ethanol results in increased expression of IL1B protein]; artesunate inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; artesunate inhibits the reaction [Glucose results in increased secretion of IL1B protein] CTD PMID:27474069 PMID:30031708 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Artesunate inhibits the reaction [Ethanol results in increased expression of IL6 protein]; Artesunate inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Artesunate inhibits the reaction [Glucose results in increased secretion of IL6 protein] CTD PMID:27474069 PMID:30031708 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) increases response to substance ISO ITGB1 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr 8:128,685,654...128,733,579
Ensembl chr 8:128,685,654...128,733,200
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 affects response to substance ISO MGST3 mRNA affects the susceptibility to artesunate CTD PMID:15796179 NCBI chr 1:167,371,966...167,393,841
Ensembl chr 1:167,371,966...167,393,841
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions ISO artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MKI67 protein] CTD PMID:29031619 NCBI chr 7:135,689,784...135,716,450
Ensembl chr 7:135,689,784...135,716,361
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MMP9 protein]
Chloroquine inhibits the reaction [Artesunate results in decreased expression of MMP9 mRNA]
CTD PMID:29031619 PMID:30551460 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO artesunate inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:27474069 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase decreases response to substance ISO MTHFD2 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 6:83,305,704...83,326,011
Ensembl chr 6:83,305,691...83,325,908
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 multiple interactions ISO artesunate inhibits the reaction [Glucose results in increased expression of MYD88 protein] CTD PMID:30031708 NCBI chr 9:119,335,934...119,340,018
Ensembl chr 9:119,335,934...119,341,411
JBrowse link
G Naca nascent polypeptide-associated complex alpha polypeptide decreases response to substance ISO NACA mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr10:128,035,346...128,048,637
Ensembl chr10:128,035,575...128,048,637
JBrowse link
G Nckap1 NCK-associated protein 1 increases response to substance ISO NCKAP1 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr 2:80,500,512...80,581,182
Ensembl chr 2:80,500,512...80,581,380
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions
decreases expression
ISO Chloroquine inhibits the reaction [Artesunate results in decreased expression of NCOA4 mRNA]
Artesunate results in decreased expression of NCOA4 mRNA; Artesunate results in decreased expression of NCOA4 protein
CTD PMID:30551460 NCBI chr14:32,159,879...32,179,855
Ensembl chr14:32,159,865...32,179,855
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization ISO artesunate affects the localization of NFE2L2 protein CTD PMID:26340163 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO artesunate inhibits the reaction [Glucose results in increased expression of NLRP3 protein] CTD PMID:30031708 NCBI chr11:59,541,569...59,566,955
Ensembl chr11:59,541,568...59,566,956
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO artesunate results in increased cleavage of PARP1 protein CTD PMID:24704559 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein] CTD PMID:29031619 NCBI chr 2:132,249,286...132,253,180
Ensembl chr 2:132,249,162...132,253,314
JBrowse link
G Pgr progesterone receptor multiple interactions ISO artesunate binds to and results in increased activity of PGR protein CTD PMID:25752796 NCBI chr 9:8,898,900...8,968,611
Ensembl chr 9:8,899,833...8,968,611
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Carbon Tetrachloride results in increased susceptibility to Artesunate] which results in increased expression of PTGS2 mRNA; [Carbon Tetrachloride results in increased susceptibility to Artesunate] which results in increased expression of PTGS2 protein CTD PMID:30551460 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO artesunate inhibits the reaction [Ethanol results in increased expression of RELA protein]; artesunate inhibits the reaction [Glucose results in increased phosphorylation of RELA protein] CTD PMID:27474069 PMID:30031708 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rpa2 replication protein A2 increases phosphorylation ISO Artesunate results in increased phosphorylation of RPA2 protein CTD PMID:31664825 NCBI chr 4:132,768,360...132,778,746
Ensembl chr 4:132,768,332...132,778,752
JBrowse link
G Rpl41 ribosomal protein L41 decreases response to substance ISO RPL41 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr10:128,548,110...128,549,168
Ensembl chr10:128,548,114...128,549,305
JBrowse link
G Rpl6 ribosomal protein L6 decreases response to substance ISO RPL6 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 5:121,204,501...121,209,241
Ensembl chr 5:121,204,481...121,209,241
JBrowse link
G Rpl7 ribosomal protein L7 decreases response to substance ISO RPL7 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 1:16,101,295...16,104,433
Ensembl chr 1:16,101,295...16,104,662
JBrowse link
G Rps12 ribosomal protein S12 decreases response to substance ISO RPS12 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr10:23,785,183...23,787,383
Ensembl chr10:23,785,183...23,787,275
JBrowse link
G Rps15a ribosomal protein S15A decreases response to substance ISO RPS15A mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 7:118,104,374...118,116,147
Ensembl chr 7:118,104,372...118,116,188
JBrowse link
G Rps6 ribosomal protein S6 decreases response to substance ISO RPS6 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 4:86,854,099...86,857,367
Ensembl chr 4:86,854,660...86,857,412
JBrowse link
G Slc25a19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 decreases response to substance ISO SLC25A19 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr11:115,614,165...115,628,296
Ensembl chr11:115,614,178...115,628,295
JBrowse link
G Sp1 trans-acting transcription factor 1 decreases expression ISO artesunate results in decreased expression of SP1 protein CTD PMID:19513562 NCBI chr15:102,406,316...102,436,404
Ensembl chr15:102,406,143...102,436,404
JBrowse link
G Sqstm1 sequestosome 1 decreases expression
multiple interactions
ISO Artesunate results in decreased expression of SQSTM1 mRNA; Artesunate results in decreased expression of SQSTM1 protein
Chloroquine inhibits the reaction [Artesunate results in decreased expression of SQSTM1 protein]
CTD PMID:30551460 NCBI chr11:50,200,152...50,210,820
Ensembl chr11:50,199,366...50,210,827
JBrowse link
G Srsf2 serine and arginine-rich splicing factor 2 decreases response to substance ISO SRSF2 mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr11:116,849,897...116,853,675
Ensembl chr11:116,849,901...116,853,094
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 multiple interactions
increases expression
ISO Chloroquine inhibits the reaction [Artesunate results in increased expression of TIMP1 mRNA] CTD PMID:30551460 NCBI chr  X:20,870,166...20,874,737
Ensembl chr  X:20,870,166...20,874,735
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO artesunate inhibits the reaction [Glucose results in increased expression of TLR4 protein] CTD PMID:30031708 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO artesunate inhibits the reaction [Ethanol results in increased expression of TNF protein]; artesunate inhibits the reaction [Glucose results in increased expression of TNF mRNA]; artesunate inhibits the reaction [Glucose results in increased secretion of TNF protein] CTD PMID:27474069 PMID:30031708 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 affects response to substance ISO TPT1 protein affects the susceptibility to artesunate CTD PMID:15878303 NCBI chr14:75,845,256...75,848,303
Ensembl chr14:75,845,093...75,848,525
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial decreases response to substance ISO TUFM mRNA results in decreased susceptibility to artesunate CTD PMID:20144594 NCBI chr 7:126,487,271...126,490,731
Ensembl chr 7:126,487,361...126,490,731
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of VEGFA protein] CTD PMID:29031619 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Yy1 YY1 transcription factor decreases expression ISO artesunate results in decreased expression of YY1 protein CTD PMID:19513562 NCBI chr12:108,792,945...108,820,148
Ensembl chr12:108,792,973...108,820,148
JBrowse link
G Zbtb4 zinc finger and BTB domain containing 4 increases response to substance ISO ZBTB4 mRNA results in increased susceptibility to artesunate CTD PMID:20144594 NCBI chr11:69,765,912...69,784,026
Ensembl chr11:69,765,912...69,784,023
JBrowse link
aspartame term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ABCA1 mRNA CTD PMID:23783067 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ABCB4 mRNA CTD PMID:23783067 NCBI chr 5:8,893,614...8,959,226
Ensembl chr 5:8,893,717...8,959,231
JBrowse link
G Abcd1 ATP-binding cassette, sub-family D (ALD), member 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of ABCD1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ABCD1 mRNA CTD PMID:23783067 NCBI chr  X:73,716,597...73,738,534
Ensembl chr  X:73,716,597...73,738,534
JBrowse link
G Abcd2 ATP-binding cassette, sub-family D (ALD), member 2 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ABCD2 mRNA CTD PMID:23783067 NCBI chr15:91,145,871...91,192,007
Ensembl chr15:91,145,871...91,191,799
JBrowse link
G Acaa1a acetyl-Coenzyme A acyltransferase 1A multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of ACAA1A mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACAA1A mRNA CTD PMID:23783067 NCBI chr 9:119,341,028...119,350,296
Ensembl chr 9:119,339,676...119,350,299
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACAA1B mRNA CTD PMID:23783067 NCBI chr 9:119,148,043...119,157,093
Ensembl chr 9:119,148,023...119,157,093
JBrowse link
G Acacb acetyl-Coenzyme A carboxylase beta multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACACB mRNA CTD PMID:23783067 NCBI chr 5:114,146,321...114,250,761
Ensembl chr 5:114,146,535...114,250,761
JBrowse link
G Acads acyl-Coenzyme A dehydrogenase, short chain multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of ACADS mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACADS mRNA CTD PMID:23783067 NCBI chr 5:115,110,299...115,119,346
Ensembl chr 5:115,110,299...115,119,346
JBrowse link
G Acadvl acyl-Coenzyme A dehydrogenase, very long chain multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of ACADVL mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACADVL mRNA CTD PMID:23783067 NCBI chr11:70,010,183...70,015,428
Ensembl chr11:70,010,183...70,015,411
JBrowse link
G Ache acetylcholinesterase decreases activity ISO Aspartame metabolite results in decreased activity of ACHE protein CTD PMID:16129618 PMID:17580119 PMID:17673349 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466
JBrowse link
G Aco1 aconitase 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of ACO1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACO1 mRNA CTD PMID:23783067 NCBI chr 4:40,143,265...40,199,009
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ACOT1 mRNA CTD PMID:23783067 NCBI chr12:84,009,502...84,017,670
Ensembl chr12:84,009,490...84,018,371
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ADGRE1 mRNA CTD PMID:23783067 NCBI chr17:57,358,581...57,483,529
Ensembl chr17:57,358,691...57,483,527
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) decreases expression ISO Aspartame results in decreased expression of AGT mRNA CTD PMID:31655124 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression ISO Aspartame results in decreased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr13:30,336,356...30,382,867
Ensembl chr13:30,336,441...30,382,867
JBrowse link
G Alox15 arachidonate 15-lipoxygenase multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ALOX15 mRNA CTD PMID:23783067 NCBI chr11:70,344,147...70,390,538
Ensembl chr11:70,344,152...70,352,031
JBrowse link
G Apoe apolipoprotein E decreases expression ISO Aspartame results in decreased expression of APOE mRNA CTD PMID:31655124 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO
EXP
[Aspartame co-treated with Methotrexate] results in increased expression of BAX mRNA; [Aspartame co-treated with Methotrexate] results in increased expression of BAX protein
[Fats, Unsaturated co-treated with Aspartame] affects the expression of BAX mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of BAX mRNA
CTD PMID:23783067 PMID:25009784 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO [Aspartame co-treated with Methotrexate] results in decreased expression of BCL2 mRNA; [Aspartame co-treated with Methotrexate] results in decreased expression of BCL2 protein CTD PMID:25009784 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Cabp2 calcium binding protein 2 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CABP2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CABP2 mRNA CTD PMID:23783067 NCBI chr19:4,081,469...4,087,340
Ensembl chr19:4,081,578...4,087,340
JBrowse link
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CACNA1A mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNA1A mRNA CTD PMID:23783067 NCBI chr 8:84,338,631...84,640,251
Ensembl chr 8:84,338,639...84,640,246
JBrowse link
G Cacna1i calcium channel, voltage-dependent, alpha 1I subunit multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CACNA1I mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNA1I mRNA CTD PMID:23783067 NCBI chr15:80,287,238...80,398,292
Ensembl chr15:80,287,238...80,398,279
JBrowse link
G Cacna2d4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CACNA2D4 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNA2D4 mRNA CTD PMID:23783067 NCBI chr 6:119,236,524...119,352,407
Ensembl chr 6:119,236,526...119,352,407
JBrowse link
G Cacnb2 calcium channel, voltage-dependent, beta 2 subunit multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CACNB2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNB2 mRNA CTD PMID:23783067 NCBI chr 2:14,603,861...14,988,811
Ensembl chr 2:14,603,088...14,987,908
JBrowse link
G Cacng4 calcium channel, voltage-dependent, gamma subunit 4 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CACNG4 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNG4 mRNA CTD PMID:23783067 NCBI chr11:107,732,357...107,794,706
Ensembl chr11:107,732,357...107,794,557
JBrowse link
G Cacng8 calcium channel, voltage-dependent, gamma subunit 8 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CACNG8 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CACNG8 mRNA CTD PMID:23783067 NCBI chr 7:3,394,042...3,416,266
Ensembl chr 7:3,390,683...3,415,648
JBrowse link
G Calhm2 calcium homeostasis modulator family member 2 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CALHM2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CALHM2 mRNA CTD PMID:23783067 NCBI chr19:47,132,232...47,138,294
Ensembl chr19:47,105,353...47,138,294
JBrowse link
G Calr3 calreticulin 3 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CALR3 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CALR3 mRNA CTD PMID:23783067 NCBI chr 8:72,424,176...72,443,819
Ensembl chr 8:72,424,176...72,443,870
JBrowse link
G Cant1 calcium activated nucleotidase 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CANT1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CANT1 mRNA CTD PMID:23783067 NCBI chr11:118,406,289...118,419,134
Ensembl chr11:118,406,289...118,419,086
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Aspartame co-treated with Methotrexate] results in increased expression of CASP3 mRNA; [Aspartame co-treated with Methotrexate] results in increased expression of CASP3 protein modified form CTD PMID:25009784 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CASP9 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CASP9 mRNA CTD PMID:23783067 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase multiple interactions ISO [Aspartame co-treated with Methotrexate] results in increased activity of CAT protein CTD PMID:25009784 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] results in increased expression of CCL2 protein; [Sodium Glutamate co-treated with Aspartame] inhibits the reaction [Fats, Unsaturated results in increased expression of CCL2 protein] CTD PMID:23783067 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CDKN1B mRNA CTD PMID:23783067 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Cherp calcium homeostasis endoplasmic reticulum protein multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CHERP mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CHERP mRNA CTD PMID:23783067 NCBI chr 8:72,460,483...72,475,233
Ensembl chr 8:72,460,489...72,475,226
JBrowse link
G Cmc1 COX assembly mitochondrial protein 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CMC1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CMC1 mRNA CTD PMID:23783067 NCBI chr 9:118,063,983...118,150,196
Ensembl chr 9:118,064,522...118,150,177
JBrowse link
G Cox11 cytochrome c oxidase assembly protein 11, copper chaperone multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of COX11 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of COX11 mRNA CTD PMID:23783067 NCBI chr11:90,638,184...90,645,977
Ensembl chr11:90,638,173...90,644,931
JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of COX7A1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of COX7A1 mRNA CTD PMID:23783067 NCBI chr 7:30,184,171...30,186,030
Ensembl chr 7:30,184,144...30,186,078
JBrowse link
G Cox8b cytochrome c oxidase subunit 8B multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of COX8B mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of COX8B mRNA CTD PMID:23783067 NCBI chr 7:140,898,942...140,900,446
Ensembl chr 7:140,898,945...140,900,446
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1b, muscle multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of CPT1B mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CPT1B mRNA CTD PMID:23783067 NCBI chr15:89,416,405...89,425,862
Ensembl chr15:89,416,405...89,425,863
JBrowse link
G Cpt1c carnitine palmitoyltransferase 1c multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CPT1C mRNA CTD PMID:23783067 NCBI chr 7:44,958,483...44,974,880
Ensembl chr 7:44,959,372...44,974,851
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CREB1 mRNA CTD PMID:23783067 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CSF1 mRNA CTD PMID:23783067 NCBI chr 3:107,741,048...107,760,469
Ensembl chr 3:107,741,048...107,760,469
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity ISO Aspartame results in increased activity of CYP1A1 protein CTD PMID:16937917 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity ISO Aspartame results in increased activity of CYP1A2 protein CTD PMID:16937917 NCBI chr 9:57,676,937...57,683,655
Ensembl chr 9:57,676,937...57,683,703
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions ISO Aspartame results in increased expression of and results in increased activity of CYP2B1 protein CTD PMID:16937917 NCBI chr 7:25,897,658...25,926,624
Ensembl chr 7:25,897,620...25,926,624
JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 increases activity ISO Aspartame results in increased activity of CYP2B2 protein CTD PMID:16937917 NCBI chr 7:26,061,388...26,096,197
Ensembl chr 7:26,061,497...26,096,197
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Aspartame results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:16937917 NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CYP4A10 mRNA CTD PMID:23783067 NCBI chr 4:115,518,287...115,533,649
Ensembl chr 4:115,518,264...115,533,649
JBrowse link
G Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of CYP4A14 mRNA CTD PMID:23783067 NCBI chr 4:115,486,200...115,496,158
Ensembl chr 4:115,486,200...115,496,142
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of DIABLO mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of DIABLO mRNA CTD PMID:23783067 NCBI chr 5:123,511,330...123,524,164
Ensembl chr 5:123,509,765...123,524,176
JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of DNAJC27 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of DNAJC27 mRNA CTD PMID:23783067 NCBI chr12:4,082,569...4,124,140
Ensembl chr12:4,082,583...4,110,606
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of E2F1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of E2F1 mRNA CTD PMID:23783067 NCBI chr 2:154,559,400...154,569,892
Ensembl chr 2:154,559,407...154,569,892
JBrowse link
G Edn2 endothelin 2 decreases expression ISO Aspartame results in decreased expression of EDN2 mRNA CTD PMID:31655124 NCBI chr 4:120,161,206...120,167,360
Ensembl chr 4:120,161,206...120,167,360
JBrowse link
G Ednra endothelin receptor type A decreases expression ISO Aspartame results in decreased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr 8:77,663,029...77,724,452
Ensembl chr 8:77,663,031...77,724,464
JBrowse link
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of EHHADH mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of EHHADH mRNA CTD PMID:23783067 NCBI chr16:21,761,285...21,787,834
Ensembl chr16:21,761,287...21,787,807
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of EPHX2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of EPHX2 mRNA CTD PMID:23783067 NCBI chr14:66,084,372...66,124,522
Ensembl chr14:66,084,374...66,124,500
JBrowse link
G F2 coagulation factor II decreases activity ISO Aspartame analog results in decreased activity of F2 protein; Aspartame results in decreased activity of F2 protein CTD PMID:15572260 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO Aspartame results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:38,838,672...38,929,470
Ensembl chr18:38,838,673...38,929,472
JBrowse link
G Foxo3 forkhead box O3 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of FOXO3 mRNA CTD PMID:23783067 NCBI chr10:42,181,845...42,276,695
Ensembl chr10:42,181,841...42,276,755
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of GADD45B mRNA CTD PMID:23783067 NCBI chr10:80,930,091...80,932,204
Ensembl chr10:80,930,073...80,932,204
JBrowse link
G Gfm2 G elongation factor, mitochondrial 2 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of GFM2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of GFM2 mRNA CTD PMID:23783067 NCBI chr13:97,137,933...97,181,202
Ensembl chr13:97,137,937...97,181,195
JBrowse link
G Gip gastric inhibitory polypeptide multiple interactions EXP Aspartame promotes the reaction [Fats, Unsaturated results in increased expression of GIP protein]; Sodium Glutamate inhibits the reaction [Aspartame promotes the reaction [Fats, Unsaturated results in increased expression of GIP protein]] CTD PMID:23783067 NCBI chr11:96,024,532...96,030,831
Ensembl chr11:96,024,545...96,030,831
JBrowse link
G Gsr glutathione reductase multiple interactions ISO [Aspartame co-treated with Methotrexate] results in decreased activity of GSR protein CTD PMID:25009784 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of HADHA mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HADHA mRNA CTD PMID:23783067 NCBI chr 5:30,119,423...30,154,980
Ensembl chr 5:30,118,304...30,155,162
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of HADHB mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HADHB mRNA CTD PMID:23783067 NCBI chr 5:30,155,253...30,184,593
Ensembl chr 5:30,155,248...30,184,593
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HDAC1 mRNA CTD PMID:23783067 NCBI chr 4:129,516,104...129,542,646
Ensembl chr 4:129,516,104...129,542,713
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HDAC5 mRNA CTD PMID:23783067 NCBI chr11:102,195,747...102,230,172
Ensembl chr11:102,194,432...102,230,166
JBrowse link
G Hgf hepatocyte growth factor multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HGF mRNA CTD PMID:23783067 NCBI chr 5:16,553,495...16,619,439
Ensembl chr 5:16,553,495...16,620,152
JBrowse link
G Hras Harvey rat sarcoma virus oncogene increases expression EXP Aspartame results in increased expression of HRAS CTD PMID:17354619 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Hspg2 perlecan (heparan sulfate proteoglycan 2) multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of HSPG2 mRNA CTD PMID:23783067 NCBI chr 4:137,468,751...137,570,630
Ensembl chr 4:137,468,769...137,570,630
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of IDH2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of IDH2 mRNA CTD PMID:23783067 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
G Il11 interleukin 11 decreases expression ISO Aspartame results in decreased expression of IL11 mRNA CTD PMID:31655124 NCBI chr 7:4,772,373...4,782,907
Ensembl chr 7:4,772,373...4,782,859
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Aspartame results in increased expression of IL1B mRNA CTD PMID:31655124 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il3 interleukin 3 decreases expression ISO Aspartame results in decreased expression of IL3 mRNA CTD PMID:31655124 NCBI chr11:54,265,085...54,267,279
Ensembl chr11:54,265,303...54,267,277
JBrowse link
G Il6 interleukin 6 increases secretion ISO Aspartame results in increased secretion of IL6 protein CTD PMID:20837131 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Immt inner membrane protein, mitochondrial multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of IMMT mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of IMMT mRNA CTD PMID:23783067 NCBI chr 6:71,831,091...71,875,266
Ensembl chr 6:71,831,331...71,877,388
JBrowse link
G Ins2 insulin II increases expression
multiple interactions
ISO
EXP
Aspartame results in increased expression of INS protein
[Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] results in increased expression of INS2 protein; Aspartame inhibits the reaction [Fats, Unsaturated results in increased expression of INS2 protein]
CTD PMID:1805284 PMID:23783067 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381
JBrowse link
G Kdr kinase insert domain protein receptor increases secretion ISO Aspartame results in increased secretion of KDR protein CTD PMID:20837131 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Lep leptin decreases expression
multiple interactions
ISO
EXP
Aspartame results in decreased expression of LEP protein
[Fats, Unsaturated co-treated with Aspartame] results in increased expression of LEP protein; [Sodium Glutamate co-treated with Aspartame] promotes the reaction [Fats, Unsaturated results in increased expression of LEP protein]
CTD PMID:11890951 PMID:23783067 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Lipg lipase, endothelial multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of LIPG mRNA CTD PMID:23783067 NCBI chr18:74,939,322...74,961,263
Ensembl chr18:74,939,322...74,961,263
JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of LRP1 mRNA CTD PMID:23783067 NCBI chr10:127,538,157...127,621,148
Ensembl chr10:127,538,161...127,621,148
JBrowse link
G Lrp2 low density lipoprotein receptor-related protein 2 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of LRP2 mRNA CTD PMID:23783067 NCBI chr 2:69,424,335...69,586,029
Ensembl chr 2:69,424,340...69,586,065
JBrowse link
G Lrp4 low density lipoprotein receptor-related protein 4 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of LRP4 mRNA CTD PMID:23783067 NCBI chr 2:91,457,456...91,513,901
Ensembl chr 2:91,457,511...91,513,779
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation ISO Aspartame results in increased phosphorylation of MAPK1 protein CTD PMID:20837131 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation ISO Aspartame results in increased phosphorylation of MAPK3 protein CTD PMID:20837131 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mcu mitochondrial calcium uniporter multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MCU mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MCU mRNA CTD PMID:23783067 NCBI chr10:59,446,984...59,617,409
Ensembl chr10:59,446,984...59,616,692
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MDM2 mRNA CTD PMID:23783067 NCBI chr10:117,688,875...117,710,758
Ensembl chr10:117,688,875...117,710,758
JBrowse link
G Med23 mediator complex subunit 23 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MED23 mRNA CTD PMID:23783067 NCBI chr10:24,869,986...24,913,529
Ensembl chr10:24,869,986...24,913,681
JBrowse link
G Mef2d myocyte enhancer factor 2D multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MEF2D mRNA CTD PMID:23783067 NCBI chr 3:88,141,941...88,172,091
Ensembl chr 3:88,142,372...88,172,086
JBrowse link
G Micos10 mitochondrial contact site and cristae organizing system subunit 10 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MINOS1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MINOS1 mRNA CTD PMID:23783067 NCBI chr 4:139,101,814...139,131,113
Ensembl chr 4:139,101,814...139,131,113
JBrowse link
G Micu1 mitochondrial calcium uptake 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MICU1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MICU1 mRNA CTD PMID:23783067 NCBI chr10:59,702,563...59,864,134
Ensembl chr10:59,702,477...59,864,132
JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MRPL20 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPL20 mRNA CTD PMID:23783067 NCBI chr 4:155,802,878...155,808,831
Ensembl chr 4:155,802,878...155,809,975
JBrowse link
G Mrpl3 mitochondrial ribosomal protein L3 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MRPL3 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPL3 mRNA CTD PMID:23783067 NCBI chr 9:105,053,268...105,077,466
Ensembl chr 9:105,053,239...105,079,888
JBrowse link
G Mrps12 mitochondrial ribosomal protein S12 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MRPS12 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPS12 mRNA CTD PMID:23783067 NCBI chr 7:28,739,641...28,741,821
Ensembl chr 7:28,739,641...28,741,820
JBrowse link
G Mrps24 mitochondrial ribosomal protein S24 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MRPS24 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPS24 mRNA CTD PMID:23783067 NCBI chr11:5,703,982...5,707,701
Ensembl chr11:5,703,983...5,715,680
JBrowse link
G Mrps27 mitochondrial ribosomal protein S27 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MRPS27 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPS27 mRNA CTD PMID:23783067 NCBI chr13:99,344,767...99,415,562
Ensembl chr13:99,344,786...99,415,562
JBrowse link
G Mrps7 mitchondrial ribosomal protein S7 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MRPS7 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MRPS7 mRNA CTD PMID:23783067 NCBI chr11:115,604,140...115,608,036
Ensembl chr11:115,603,925...115,608,036
JBrowse link
G Mtfp1 mitochondrial fission process 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of MTFP1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MTFP1 mRNA CTD PMID:23783067 NCBI chr11:4,091,481...4,095,431
Ensembl chr11:4,091,480...4,095,445
JBrowse link
G Myc myelocytomatosis oncogene increases expression EXP Aspartame results in increased expression of MYC CTD PMID:17354619 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NCOR1 mRNA CTD PMID:23783067 NCBI chr11:62,315,663...62,457,414
Ensembl chr11:62,316,426...62,458,541
JBrowse link
G Ndufa12 NADH:ubiquinone oxidoreductase subunit A12 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of NDUFA12 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFA12 mRNA CTD PMID:23783067 NCBI chr10:94,199,035...94,221,440
Ensembl chr10:94,198,720...94,221,443
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of NDUFA5 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFA5 mRNA CTD PMID:23783067 NCBI chr 6:24,518,662...24,527,690
Ensembl chr 6:24,518,666...24,528,013
JBrowse link
G Ndufb10 NADH:ubiquinone oxidoreductase subunit B10 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of NDUFB10 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFB10 mRNA CTD PMID:23783067 NCBI chr17:24,722,060...24,724,423
Ensembl chr17:24,722,060...24,724,478
JBrowse link
G Ndufb2 NADH:ubiquinone oxidoreductase subunit B2 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of NDUFB2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFB2 mRNA CTD PMID:23783067 NCBI chr 6:39,592,565...39,599,843
Ensembl chr 6:39,592,574...39,603,382
JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of NDUFB6 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFB6 mRNA CTD PMID:23783067 NCBI chr 4:40,270,591...40,279,421
Ensembl chr 4:40,270,591...40,279,421
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of NDUFS1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFS1 mRNA CTD PMID:23783067 NCBI chr 1:63,143,592...63,176,822
Ensembl chr 1:63,143,596...63,176,833
JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase core subunit S6 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of NDUFS6 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFS6 mRNA CTD PMID:23783067 NCBI chr13:73,319,876...73,328,482
Ensembl chr13:73,319,838...73,328,542
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of NDUFV1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NDUFV1 mRNA CTD PMID:23783067 NCBI chr19:4,007,499...4,012,755
Ensembl chr19:4,007,384...4,012,806
JBrowse link
G Nf1 neurofibromin 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NF1 mRNA CTD PMID:23783067 NCBI chr11:79,339,590...79,581,609
Ensembl chr11:79,339,693...79,581,612
JBrowse link
G Notch1 notch 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NOTCH1 mRNA CTD PMID:23783067 NCBI chr 2:26,457,902...26,503,822
Ensembl chr 2:26,457,903...26,516,663
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NOX1 mRNA CTD PMID:23783067 NCBI chr  X:134,086,421...134,137,711
Ensembl chr  X:134,086,421...134,221,956
JBrowse link
G Nppb natriuretic peptide type B decreases expression ISO Aspartame results in decreased expression of NPPB mRNA CTD PMID:31655124 NCBI chr 4:147,985,786...147,987,205
Ensembl chr 4:147,985,788...147,987,205
JBrowse link
G Npy neuropeptide Y decreases expression ISO Aspartame results in decreased expression of NPY protein CTD PMID:11890951 NCBI chr 6:49,822,710...49,829,507
Ensembl chr 6:49,822,710...49,829,507
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NR1I3 mRNA CTD PMID:23783067 NCBI chr 1:171,213,934...171,218,845
Ensembl chr 1:171,213,970...171,220,701
JBrowse link
G Onecut1 one cut domain, family member 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ONECUT1 mRNA CTD PMID:23783067 NCBI chr 9:74,861,921...74,889,648
Ensembl chr 9:74,861,921...74,891,781
JBrowse link
G Pdha2 pyruvate dehydrogenase E1 alpha 2 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PDHA2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PDHA2 mRNA CTD PMID:23783067 NCBI chr 3:141,210,004...141,212,355
Ensembl chr 3:141,210,004...141,212,355
JBrowse link
G Pdhb pyruvate dehydrogenase (lipoamide) beta multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PDHB mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PDHB mRNA CTD PMID:23783067 NCBI chr14:8,165,991...8,173,303
Ensembl chr14:8,165,996...8,173,025
JBrowse link
G Pex1 peroxisomal biogenesis factor 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PEX1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX1 mRNA CTD PMID:23783067 NCBI chr 5:3,596,066...3,637,230
Ensembl chr 5:3,596,066...3,637,232
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PEX11A mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX11A mRNA CTD PMID:23783067 NCBI chr 7:79,735,957...79,743,131
Ensembl chr 7:79,735,957...79,743,131
JBrowse link
G Pex13 peroxisomal biogenesis factor 13 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PEX13 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX13 mRNA CTD PMID:23783067 NCBI chr11:23,646,843...23,665,883
Ensembl chr11:23,646,479...23,665,959
JBrowse link
G Pex5 peroxisomal biogenesis factor 5 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PEX5 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX5 mRNA CTD PMID:23783067 NCBI chr 6:124,396,816...124,415,944
Ensembl chr 6:124,396,816...124,415,067
JBrowse link
G Pex7 peroxisomal biogenesis factor 7 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PEX7 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PEX7 mRNA CTD PMID:23783067 NCBI chr10:19,860,090...19,907,674
Ensembl chr10:19,853,900...19,907,689
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PFKFB2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PFKFB2 mRNA CTD PMID:23783067 NCBI chr 1:130,689,043...130,729,253
Ensembl chr 1:130,689,182...130,729,253
Ensembl chr 1:130,689,182...130,729,253
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PFKFB4 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PFKFB4 mRNA CTD PMID:23783067 NCBI chr 9:108,988,272...109,032,236
Ensembl chr 9:108,991,778...109,032,228
JBrowse link
G Pld2 phospholipase D2 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PLD2 mRNA CTD PMID:23783067 NCBI chr11:70,539,492...70,558,110
Ensembl chr11:70,540,064...70,558,110
JBrowse link
G Plg plasminogen decreases expression ISO Aspartame results in decreased expression of PLG mRNA CTD PMID:31655124 NCBI chr17:12,378,609...12,419,384
Ensembl chr17:12,378,608...12,419,385
JBrowse link
G Plxnd1 plexin D1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PLXND1 mRNA CTD PMID:23783067 NCBI chr 6:115,954,811...115,995,339
Ensembl chr 6:115,954,811...115,995,005
JBrowse link
G Polg polymerase (DNA directed), gamma multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of POLG mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of POLG mRNA CTD PMID:23783067 NCBI chr 7:79,446,231...79,467,911
Ensembl chr 7:79,446,231...79,466,362
JBrowse link
G Pomc pro-opiomelanocortin-alpha increases expression ISO Aspartame results in increased expression of POMC protein alternative form CTD PMID:1805284 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PPARA mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PPARA mRNA CTD PMID:23783067 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Ppard peroxisome proliferator activator receptor delta multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PPARD mRNA CTD PMID:23783067 NCBI chr17:28,232,754...28,301,469
Ensembl chr17:28,232,700...28,301,474
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PPARG mRNA CTD PMID:23783067 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PPARGC1A mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PPARGC1A mRNA CTD PMID:23783067 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
G Prdx5 peroxiredoxin 5 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of PRDX5 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of PRDX5 mRNA CTD PMID:23783067 NCBI chr19:6,906,697...6,910,106
Ensembl chr19:6,906,697...6,910,106
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of ROCK1 mRNA CTD PMID:23783067 NCBI chr18:10,064,401...10,182,251
Ensembl chr18:10,064,401...10,182,045
JBrowse link
G S100a13 S100 calcium binding protein A13 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of S100A13 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of S100A13 mRNA CTD PMID:23783067 NCBI chr 3:90,514,233...90,524,581
Ensembl chr 3:90,514,435...90,524,581
JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of S100A8 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of S100A8 mRNA CTD PMID:23783067 NCBI chr 3:90,669,071...90,670,034
Ensembl chr 3:90,668,978...90,670,035
JBrowse link
G Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of SDHB mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SDHB mRNA CTD PMID:23783067 NCBI chr 4:140,961,271...140,979,198
Ensembl chr 4:140,961,203...140,979,193
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SIRT1 mRNA CTD PMID:23783067 NCBI chr10:63,319,005...63,339,035
Ensembl chr10:63,319,005...63,381,704
JBrowse link
G Sirt2 sirtuin 2 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SIRT2 mRNA CTD PMID:23783067 NCBI chr 7:28,766,752...28,788,665
Ensembl chr 7:28,766,735...28,788,661
JBrowse link
G Slc15a1 solute carrier family 15 (oligopeptide transporter), member 1 decreases activity ISO Aspartame results in decreased activity of SLC15A1 protein CTD PMID:15846457 NCBI chr14:121,459,621...121,505,254
Ensembl chr14:121,459,621...121,505,252
JBrowse link
G Slc4a2 solute carrier family 4 (anion exchanger), member 2 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SLC4A2 mRNA CTD PMID:23783067 NCBI chr 5:24,423,761...24,440,947
Ensembl chr 5:24,423,837...24,440,950
JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of SLC8A1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SLC8A1 mRNA CTD PMID:23783067 NCBI chr17:81,373,105...81,738,387
Ensembl chr17:81,373,105...81,738,377
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SREBF2 mRNA CTD PMID:23783067 NCBI chr15:82,147,269...82,205,379
Ensembl chr15:82,147,181...82,205,379
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of STAT3 mRNA CTD PMID:23783067 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Surf1 surfeit gene 1 multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of SURF1 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SURF1 mRNA CTD PMID:23783067 NCBI chr 2:26,913,378...26,916,610
Ensembl chr 2:26,913,381...26,916,530
JBrowse link
G Tas1r2 taste receptor, type 1, member 2 multiple interactions
affects binding
ISO Aspartame binds to and results in increased activity of TAS1R2 protein; lactisole inhibits the reaction [Aspartame results in increased activity of [TAS1R3 protein binds to TAS1R2 protein]]
Aspartame binds to [TAS1R2 protein binds to TAS1R3 protein]; Aspartame binds to TAS1R2 protein
CTD PMID:15353592 PMID:17168764 PMID:17935609 PMID:20173092 NCBI chr 4:139,653,538...139,670,280
Ensembl chr 4:139,653,538...139,670,280
JBrowse link
G Tas1r3 taste receptor, type 1, member 3 affects binding
multiple interactions
ISO Aspartame binds to [TAS1R2 protein binds to TAS1R3 protein]
lactisole inhibits the reaction [Aspartame results in increased activity of [TAS1R3 protein binds to TAS1R2 protein]]
CTD PMID:17168764 PMID:17935609 NCBI chr 4:155,859,268...155,863,353
Ensembl chr 4:155,859,268...155,863,362
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of TFAM mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of TFAM mRNA CTD PMID:23783067 NCBI chr10:71,225,468...71,238,328
Ensembl chr10:71,225,464...71,238,280
JBrowse link
G Thbs1 thrombospondin 1 multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of THBS1 mRNA CTD PMID:23783067 NCBI chr 2:118,111,876...118,127,133
Ensembl chr 2:118,111,876...118,127,133
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] results in increased expression of TNF protein; [Sodium Glutamate co-treated with Aspartame] promotes the reaction [Fats, Unsaturated results in increased expression of TNF protein] CTD PMID:23783067 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Trp53 transformation related protein 53 increases expression
multiple interactions
EXP Aspartame results in increased expression of TRP53
[Fats, Unsaturated co-treated with Aspartame] affects the expression of TRP53 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of TRP53 mRNA
CTD PMID:17354619 PMID:23783067 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity ISO Aspartame results in increased activity of TRPV1 protein CTD PMID:17567713 PMID:18804451 NCBI chr11:73,234,149...73,261,322
Ensembl chr11:73,234,292...73,261,242
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of TUFM mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of TUFM mRNA CTD PMID:23783067 NCBI chr 7:126,487,271...126,490,731
Ensembl chr 7:126,487,361...126,490,731
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of UCP2 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of UCP2 mRNA CTD PMID:23783067 NCBI chr 7:100,493,337...100,499,629
Ensembl chr 7:100,493,337...100,502,020
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI multiple interactions EXP [Fats, Unsaturated co-treated with Aspartame] affects the expression of UQCR11 mRNA; [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of UQCR11 mRNA CTD PMID:23783067 NCBI chr10:80,402,997...80,406,821
Ensembl chr10:80,402,997...80,406,830
JBrowse link
G Vegfa vascular endothelial growth factor A increases secretion ISO Aspartame results in increased secretion of VEGFA protein CTD PMID:20837131 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of XDH mRNA CTD PMID:23783067 NCBI chr17:73,883,895...73,950,397
Ensembl chr17:73,883,895...73,950,196
JBrowse link
citraconic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bach1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 affects localization ISO citraconic acid affects the localization of BACH1 protein CTD PMID:27277809 NCBI chr16:87,698,954...87,733,346
Ensembl chr16:87,698,945...87,733,346
JBrowse link
G Foxm1 forkhead box M1 increases expression ISO citraconic acid results in increased expression of FOXM1 protein CTD PMID:28289076 NCBI chr 6:128,362,994...128,375,886
Ensembl chr 6:128,362,967...128,376,146
JBrowse link
G Fth1 ferritin heavy polypeptide 1 increases expression ISO citraconic acid results in increased expression of FTH1 protein CTD PMID:28289076 NCBI chr19:9,980,600...9,985,111
Ensembl chr19:9,980,598...9,985,098
JBrowse link
G Ftl1 ferritin light polypeptide 1 increases expression
multiple interactions
ISO citraconic acid results in increased expression of FTL protein
citraconic acid promotes the reaction [NFE2L2 protein results in increased expression of FTL protein]; NFE2L2 protein affects the reaction [citraconic acid results in increased expression of FTL protein]
CTD PMID:28289076 NCBI chr 7:45,457,944...45,459,886
Ensembl chr 7:45,457,944...45,459,884
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO
EXP
citraconic acid results in increased expression of GCLC protein
citraconic acid results in increased expression of GCLC mRNA
CTD PMID:27277809 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression EXP
ISO
citraconic acid results in increased expression of GCLM mRNA
citraconic acid results in increased expression of GCLM protein
CTD PMID:27277809 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Gsr glutathione reductase increases expression ISO
EXP
citraconic acid results in increased expression of GSR protein
citraconic acid results in increased expression of GSR mRNA
CTD PMID:27277809 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP
ISO
citraconic acid results in increased expression of HMOX1 mRNA
citraconic acid results in increased expression of HMOX1 mRNA; citraconic acid results in increased expression of HMOX1 protein
CTD PMID:27277809 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G mt-Cytb cytochrome b, mitochondrial increases expression
multiple interactions
EXP citraconic acid results in increased expression of CYTB mRNA
NFE2L2 protein affects the reaction [citraconic acid results in increased expression of CYTB mRNA]
CTD PMID:27277809 NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288
JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial increases expression
multiple interactions
EXP citraconic acid results in increased expression of ND1 mRNA
NFE2L2 protein affects the reaction [citraconic acid results in increased expression of ND1 mRNA]
CTD PMID:27277809 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707
JBrowse link
G mt-Nd5 NADH dehydrogenase 5, mitochondrial multiple interactions
increases expression
EXP NFE2L2 protein affects the reaction [citraconic acid results in increased expression of ND5 mRNA] CTD PMID:27277809 NCBI chr MT:11,742...13,565
Ensembl chr MT:11,742...13,565
JBrowse link
G mt-Nd6 NADH dehydrogenase 6, mitochondrial multiple interactions
increases expression
EXP NFE2L2 protein affects the reaction [citraconic acid results in increased expression of ND6 mRNA] CTD PMID:27277809 NCBI chr MT:13,552...14,070
Ensembl chr MT:13,552...14,070
JBrowse link
G Mterf1a mitochondrial transcription termination factor 1a increases expression EXP citraconic acid results in increased expression of MTERF1A mRNA CTD PMID:27277809 NCBI chr 5:3,864,565...3,893,933
Ensembl chr 5:3,890,581...3,893,933
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization
multiple interactions
ISO
EXP
citraconic acid affects the localization of NFE2L2 protein
citraconic acid promotes the reaction [NFE2L2 protein results in increased expression of FTL protein]; NFE2L2 protein affects the reaction [citraconic acid results in increased expression of FTL protein]
NFE2L2 protein affects the reaction [citraconic acid results in increased expression of CYTB mRNA]; NFE2L2 protein affects the reaction [citraconic acid results in increased expression of ND1 mRNA]; NFE2L2 protein affects the reaction [citraconic acid results in increased expression of ND5 mRNA]; NFE2L2 protein affects the reaction [citraconic acid results in increased expression of ND6 mRNA]; NFE2L2 protein affects the reaction [citraconic acid results in increased expression of POLRMT mRNA]
CTD PMID:27277809 PMID:28289076 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO citraconic acid results in increased expression of NQO1 mRNA; citraconic acid results in increased expression of NQO1 protein CTD PMID:27277809 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Polrmt polymerase (RNA) mitochondrial (DNA directed) multiple interactions
increases expression
EXP NFE2L2 protein affects the reaction [citraconic acid results in increased expression of POLRMT mRNA] CTD PMID:27277809 NCBI chr10:79,736,125...79,746,604
Ensembl chr10:79,736,123...79,746,581
JBrowse link
diethyl fumarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases cleavage ISO diethyl fumarate results in increased cleavage of CASP3 protein CTD PMID:21105742 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO diethyl fumarate results in increased cleavage of PARP1 protein CTD PMID:21105742 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Sptan1 spectrin alpha, non-erythrocytic 1 increases cleavage ISO diethyl fumarate results in increased cleavage of SPTAN1 protein CTD PMID:21105742 NCBI chr 2:29,965,560...30,031,451
Ensembl chr 2:29,965,560...30,031,451
JBrowse link
diethyl malate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin, alpha 2, smooth muscle, aorta affects expression EXP diethyl malate affects the expression of ACTA2 mRNA CTD PMID:24814887 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 affects expression EXP diethyl malate affects the expression of ACTC1 mRNA CTD PMID:24814887 NCBI chr 2:114,047,282...114,052,875
Ensembl chr 2:114,047,282...114,053,548
JBrowse link
G Actn3 actinin alpha 3 affects expression EXP diethyl malate affects the expression of ACTN3 mRNA CTD PMID:24814887 NCBI chr19:4,861,216...4,877,909
Ensembl chr19:4,861,216...4,877,909
JBrowse link
G Adcy1 adenylate cyclase 1 affects expression EXP diethyl malate affects the expression of ADCY1 mRNA CTD PMID:24814887 NCBI chr11:7,063,433...7,178,506
Ensembl chr11:7,063,489...7,178,506
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) affects expression EXP diethyl malate affects the expression of ADH1 mRNA CTD PMID:24814887 NCBI chr 3:138,277,585...138,290,698
Ensembl chr 3:138,260,991...138,290,698
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) affects expression EXP diethyl malate affects the expression of AGT mRNA CTD PMID:24814887 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 affects expression EXP diethyl malate affects the expression of ALDH1A7 mRNA CTD PMID:24814887 NCBI chr19:20,692,953...20,727,556
Ensembl chr19:20,692,953...20,727,562
JBrowse link
G C3 complement component 3 affects expression EXP diethyl malate affects the expression of C3 mRNA CTD PMID:24814887 NCBI chr17:57,203,967...57,228,136
Ensembl chr17:57,203,970...57,228,136
JBrowse link
G Cacnb2 calcium channel, voltage-dependent, beta 2 subunit affects expression EXP diethyl malate affects the expression of CACNB2 mRNA CTD PMID:24814887 NCBI chr 2:14,603,861...14,988,811
Ensembl chr 2:14,603,088...14,987,908
JBrowse link
G Cacnb4 calcium channel, voltage-dependent, beta 4 subunit affects expression EXP diethyl malate affects the expression of CACNB4 mRNA CTD PMID:24814887 NCBI chr 2:52,428,320...52,676,609
Ensembl chr 2:52,428,320...52,676,831
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
affects expression
EXP S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of CAMK2A mRNA] CTD PMID:24814887 NCBI chr18:60,925,307...60,988,152
Ensembl chr18:60,925,618...60,988,152
JBrowse link
G Cbr2 carbonyl reductase 2 affects expression EXP diethyl malate affects the expression of CBR2 mRNA CTD PMID:24814887 NCBI chr11:120,729,485...120,732,025
Ensembl chr11:120,729,489...120,732,114
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 affects expression EXP diethyl malate affects the expression of CCL20 mRNA CTD PMID:24814887 NCBI chr 1:83,116,766...83,119,167
Ensembl chr 1:83,116,766...83,119,167
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 affects expression EXP diethyl malate affects the expression of CCL6 mRNA CTD PMID:24814887 NCBI chr11:83,587,886...83,593,087
Ensembl chr11:83,587,882...83,593,087
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 affects expression EXP diethyl malate affects the expression of CCL7 mRNA CTD PMID:24814887 NCBI chr11:82,045,712...82,047,525
Ensembl chr11:82,045,712...82,047,525
JBrowse link
G Ccl9 chemokine (C-C motif) ligand 9 affects expression EXP diethyl malate affects the expression of CCL9 mRNA CTD PMID:24814887 NCBI chr11:83,572,917...83,578,636
Ensembl chr11:83,572,919...83,578,636
JBrowse link
G Col11a1 collagen, type XI, alpha 1 affects expression EXP diethyl malate affects the expression of COL11A1 mRNA CTD PMID:24814887 NCBI chr 3:114,030,479...114,220,756
Ensembl chr 3:114,030,540...114,220,718
JBrowse link
G Col2a1 collagen, type II, alpha 1 affects expression EXP diethyl malate affects the expression of COL2A1 mRNA CTD PMID:24814887 NCBI chr15:97,975,602...98,004,724
Ensembl chr15:97,975,602...98,004,695
JBrowse link
G Col3a1 collagen, type III, alpha 1 affects expression EXP diethyl malate affects the expression of COL3A1 mRNA CTD PMID:24814887 NCBI chr 1:45,311,538...45,349,706
Ensembl chr 1:45,311,538...45,349,706
JBrowse link
G Col6a1 collagen, type VI, alpha 1 affects expression EXP diethyl malate affects the expression of COL6A1 mRNA CTD PMID:24814887 NCBI chr10:76,708,792...76,726,044
Ensembl chr10:76,708,792...76,726,168
JBrowse link
G Comp cartilage oligomeric matrix protein affects expression EXP diethyl malate affects the expression of COMP mRNA CTD PMID:24814887 NCBI chr 8:70,373,548...70,382,066
Ensembl chr 8:70,373,558...70,382,066
JBrowse link
G Cxcl12 chemokine (C-X-C motif) ligand 12 affects expression
multiple interactions
EXP diethyl malate affects the expression of CXCL12 mRNA
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of CXCL12 mRNA]
CTD PMID:24814887 NCBI chr 6:117,168,535...117,181,368
Ensembl chr 6:117,168,535...117,181,367
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 affects expression EXP diethyl malate affects the expression of CXCL5 mRNA CTD PMID:24814887 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 affects expression EXP diethyl malate affects the expression of CXCL1 mRNA CTD PMID:24814887 NCBI chr 5:90,786,101...90,788,093
Ensembl chr 5:90,786,103...90,789,600
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 affects expression EXP diethyl malate affects the expression of CYP2J9 mRNA CTD PMID:24814887 NCBI chr 4:96,568,424...96,592,523
Ensembl chr 4:96,568,429...96,591,578
JBrowse link
G Dapk2 death-associated protein kinase 2 affects expression EXP diethyl malate affects the expression of DAPK2 mRNA CTD PMID:24814887 NCBI chr 9:66,158,226...66,272,242
Ensembl chr 9:66,158,223...66,272,242
JBrowse link
G Ddx58 DEAD/H box helicase 58 affects expression EXP diethyl malate affects the expression of DDX58 mRNA CTD PMID:24814887 NCBI chr 4:40,203,777...40,239,825
Ensembl chr 4:40,203,773...40,239,828
JBrowse link
G Dhrs3 dehydrogenase/reductase (SDR family) member 3 affects expression EXP diethyl malate affects the expression of DHRS3 mRNA CTD PMID:24814887 NCBI chr 4:144,892,534...144,928,209
Ensembl chr 4:144,892,827...144,928,209
JBrowse link
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 affects expression EXP diethyl malate affects the expression of DHX58 mRNA CTD PMID:24814887 NCBI chr11:100,694,884...100,704,271
Ensembl chr11:100,694,884...100,704,271
JBrowse link
G Edar ectodysplasin-A receptor affects expression EXP diethyl malate affects the expression of EDAR mRNA CTD PMID:24814887 NCBI chr10:58,600,780...58,675,696
Ensembl chr10:58,600,789...58,675,654
JBrowse link
G Ednra endothelin receptor type A affects expression EXP diethyl malate affects the expression of EDNRA mRNA CTD PMID:24814887 NCBI chr 8:77,663,029...77,724,452
Ensembl chr 8:77,663,031...77,724,464
JBrowse link
G Epas1 endothelial PAS domain protein 1 affects expression EXP diethyl malate affects the expression of EPAS1 mRNA CTD PMID:24814887 NCBI chr17:86,753,864...86,833,410
Ensembl chr17:86,753,700...86,833,410
JBrowse link
G Epha7 Eph receptor A7 affects expression EXP diethyl malate affects the expression of EPHA7 mRNA CTD PMID:24814887 NCBI chr 4:28,813,066...28,967,503
Ensembl chr 4:28,813,131...28,967,499
JBrowse link
G Ephb2 Eph receptor B2 affects expression EXP diethyl malate affects the expression of EPHB2 mRNA CTD PMID:24814887 NCBI chr 4:136,647,536...136,836,326
Ensembl chr 4:136,647,539...136,835,988
JBrowse link
G Ephb6 Eph receptor B6 affects expression EXP diethyl malate affects the expression of EPHB6 mRNA CTD PMID:24814887 NCBI chr 6:41,603,834...41,620,509
Ensembl chr 6:41,605,482...41,620,509
JBrowse link
G Fgf10 fibroblast growth factor 10 affects expression EXP diethyl malate affects the expression of FGF10 mRNA CTD PMID:24814887 NCBI chr13:118,714,699...118,792,573
Ensembl chr13:118,669,791...118,792,115
JBrowse link
G Fgf18 fibroblast growth factor 18 multiple interactions
affects expression
EXP S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of FGF18 mRNA] CTD PMID:24814887 NCBI chr11:33,116,970...33,147,400
Ensembl chr11:33,117,430...33,147,400
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects expression EXP diethyl malate affects the expression of FGFR2 mRNA CTD PMID:24814887 NCBI chr 7:130,162,451...130,266,808
Ensembl chr 7:130,162,451...133,123,350
JBrowse link
G Fst follistatin affects expression EXP diethyl malate affects the expression of FST mRNA CTD PMID:24814887 NCBI chr13:114,452,262...114,458,989
Ensembl chr13:114,452,290...114,458,951
JBrowse link
G Fzd2 frizzled class receptor 2 affects expression EXP diethyl malate affects the expression of FZD2 mRNA CTD PMID:24814887 NCBI chr11:102,604,431...102,608,058
Ensembl chr11:102,604,396...102,608,058
JBrowse link
G Fzd7 frizzled class receptor 7 affects expression EXP diethyl malate affects the expression of FZD7 mRNA CTD PMID:24814887 NCBI chr 1:59,482,147...59,486,955
Ensembl chr 1:59,482,424...59,486,955
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression EXP diethyl malate affects the expression of GCLC mRNA CTD PMID:24814887 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions
affects expression
EXP S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GCLM mRNA] CTD PMID:24814887 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Ggt6 gamma-glutamyltransferase 6 affects expression EXP diethyl malate affects the expression of GGT6 mRNA CTD PMID:24814887 NCBI chr11:72,435,247...72,438,566
Ensembl chr11:72,435,526...72,438,400
JBrowse link
G Gli2 GLI-Kruppel family member GLI2 affects expression EXP diethyl malate affects the expression of GLI2 mRNA CTD PMID:24814887 NCBI chr 1:118,834,061...119,054,405
Ensembl chr 1:118,834,132...119,053,619
JBrowse link
G Gnao1 guanine nucleotide binding protein, alpha O affects expression EXP diethyl malate affects the expression of GNAO1 mRNA CTD PMID:24814887 NCBI chr 8:93,810,153...93,969,388
Ensembl chr 8:93,809,966...93,969,388
JBrowse link
G Gng7 guanine nucleotide binding protein (G protein), gamma 7 affects expression EXP diethyl malate affects the expression of GNG7 mRNA CTD PMID:24814887 NCBI chr10:80,948,624...81,014,925
Ensembl chr10:80,948,624...81,014,945
JBrowse link
G Gsr glutathione reductase affects expression EXP diethyl malate affects the expression of GSR mRNA CTD PMID:24814887 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gss glutathione synthetase multiple interactions
affects expression
EXP S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSS mRNA] CTD PMID:24814887 NCBI chr 2:155,563,181...155,592,810
Ensembl chr 2:155,563,181...155,592,810
JBrowse link
G Gsta2 glutathione S-transferase, alpha 2 (Yc2) affects expression
multiple interactions
EXP diethyl malate affects the expression of GSTA1 mRNA
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSTA1 mRNA]
CTD PMID:24814887 NCBI chr 9:78,331,018...78,347,192
Ensembl chr 9:78,331,018...78,355,788
JBrowse link
G Gsta3 glutathione S-transferase, alpha 3 affects expression
multiple interactions
EXP diethyl malate affects the expression of GSTA3 mRNA
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSTA3 mRNA]
CTD PMID:24814887 NCBI chr 1:21,240,565...21,265,575
Ensembl chr 1:21,240,589...21,265,661
JBrowse link
G Gucy1a1 guanylate cyclase 1, soluble, alpha 1 affects expression EXP diethyl malate affects the expression of GUCY1A1 mRNA CTD PMID:24814887 NCBI chr 3:82,092,427...82,145,946
Ensembl chr 3:82,092,427...82,145,789
JBrowse link
G Gucy1b1 guanylate cyclase 1, soluble, beta 1 affects expression EXP diethyl malate affects the expression of GUCY1B1 mRNA CTD PMID:24814887 NCBI chr 3:82,032,004...82,074,711
Ensembl chr 3:82,032,006...82,074,689
JBrowse link
G H2-DMb1 histocompatibility 2, class II, locus Mb1 affects expression EXP diethyl malate affects the expression of H2-DMB1 mRNA CTD PMID:24814887 NCBI chr17:34,153,191...34,160,229
Ensembl chr17:34,153,072...34,160,230
JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 affects expression EXP diethyl malate affects the expression of H2-M3 mRNA CTD PMID:24814887 NCBI chr17:37,270,234...37,274,485
Ensembl chr17:37,270,220...37,274,484
JBrowse link
G Hck hemopoietic cell kinase affects expression EXP diethyl malate affects the expression of HCK mRNA CTD PMID:24814887 NCBI chr 2:153,108,468...153,151,441
Ensembl chr 2:153,108,468...153,151,441
JBrowse link
G Hgf hepatocyte growth factor affects expression EXP diethyl malate affects the expression of HGF mRNA CTD PMID:24814887 NCBI chr 5:16,553,495...16,619,439
Ensembl chr 5:16,553,495...16,620,152
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression EXP diethyl malate affects the expression of IGF1 mRNA CTD PMID:24814887 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Il15 interleukin 15 affects expression EXP diethyl malate affects the expression of IL15 mRNA CTD PMID:24814887 NCBI chr 8:82,331,624...82,403,252
Ensembl chr 8:82,331,632...82,403,222
JBrowse link
G Il18 interleukin 18 affects expression EXP diethyl malate affects the expression of IL18 mRNA CTD PMID:24814887 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840
JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 affects expression EXP diethyl malate affects the expression of IRAG1 mRNA CTD PMID:24814887 NCBI chr 7:110,868,257...110,982,909
Ensembl chr 7:110,868,266...110,982,461
JBrowse link
G Irf7 interferon regulatory factor 7 affects expression EXP diethyl malate affects the expression of IRF7 mRNA CTD PMID:24814887 NCBI chr 7:141,263,183...141,266,499
Ensembl chr 7:141,262,706...141,266,481
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression EXP diethyl malate affects the expression of ISG15 mRNA CTD PMID:24814887 NCBI chr 4:156,199,424...156,200,818
Ensembl chr 4:156,199,455...156,200,796
JBrowse link
G Itga11 integrin alpha 11 affects expression EXP diethyl malate affects the expression of ITGA11 mRNA CTD PMID:24814887 NCBI chr 9:62,677,855...62,783,979
Ensembl chr 9:62,677,826...62,783,982
JBrowse link
G Itga3 integrin alpha 3 affects expression EXP diethyl malate affects the expression of ITGA3 mRNA CTD PMID:24814887 NCBI chr11:95,044,475...95,076,844
Ensembl chr11:95,044,474...95,076,801
JBrowse link
G Kcnmb4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 affects expression EXP diethyl malate affects the expression of KCNMB4 mRNA CTD PMID:24814887 NCBI chr10:116,417,861...116,473,859
Ensembl chr10:116,417,861...116,473,878
JBrowse link
G Lama1 laminin, alpha 1 affects expression EXP diethyl malate affects the expression of LAMA1 mRNA CTD PMID:24814887 NCBI chr17:67,697,127...67,822,645
Ensembl chr17:67,697,259...67,822,647
JBrowse link
G Lama4 laminin, alpha 4 affects expression EXP diethyl malate affects the expression of LAMA4 mRNA CTD PMID:24814887 NCBI chr10:38,965,515...39,110,188
Ensembl chr10:38,965,515...39,110,188
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 affects phosphorylation
multiple interactions
EXP diethyl malate affects the phosphorylation of MAPK1 protein
S-ethyl glutathione inhibits the reaction [diethyl malate affects the phosphorylation of MAPK1 protein]
CTD PMID:24814887 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 affects phosphorylation
multiple interactions
EXP diethyl malate affects the phosphorylation of MAPK3 protein
S-ethyl glutathione inhibits the reaction [diethyl malate affects the phosphorylation of MAPK3 protein]
CTD PMID:24814887 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory affects expression EXP diethyl malate affects the expression of MYL9 mRNA CTD PMID:24814887 NCBI chr 2:156,775,408...156,781,657
Ensembl chr 2:156,775,420...156,781,658
JBrowse link
G Odc1 ornithine decarboxylase, structural 1 affects expression EXP diethyl malate affects the expression of ODC1 mRNA CTD PMID:24814887 NCBI chr12:17,544,808...17,551,502
Ensembl chr12:17,544,794...17,551,505
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide affects expression
multiple interactions
EXP diethyl malate affects the expression of PDGFB mRNA
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of PDGFB mRNA]
CTD PMID:24814887 NCBI chr15:79,995,865...80,024,614
Ensembl chr15:79,995,874...80,014,977
JBrowse link
G Pdgfd platelet-derived growth factor, D polypeptide affects expression EXP diethyl malate affects the expression of PDGFD mRNA CTD PMID:24814887 NCBI chr 9:6,168,363...6,534,284
Ensembl chr 9:6,168,584...6,378,850
JBrowse link
G Pf4 platelet factor 4 affects expression EXP diethyl malate affects the expression of PF4 mRNA CTD PMID:24814887 NCBI chr 5:90,772,435...90,773,383
Ensembl chr 5:90,772,435...90,773,383
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 affects expression EXP diethyl malate affects the expression of PIK3IP1 mRNA CTD PMID:24814887 NCBI chr11:3,319,241...3,342,971
Ensembl chr11:3,330,401...3,342,971
JBrowse link
G Plxnc1 plexin C1 affects expression EXP diethyl malate affects the expression of PLXNC1 mRNA CTD PMID:24814887 NCBI chr10:94,790,866...94,945,015
Ensembl chr10:94,790,866...94,944,835
JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I affects expression EXP diethyl malate affects the expression of PRKG1 mRNA CTD PMID:24814887 NCBI chr19:30,564,487...31,765,268
Ensembl chr19:30,564,489...31,765,033
JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase affects expression EXP diethyl malate affects the expression of PTGIS mRNA CTD PMID:24814887 NCBI chr 2:167,203,194...167,252,150
Ensembl chr 2:167,191,805...167,240,604
JBrowse link
G Ramp2 receptor (calcitonin) activity modifying protein 2 affects expression EXP diethyl malate affects the expression of RAMP2 mRNA CTD PMID:24814887 NCBI chr11:101,246,334...101,248,250
Ensembl chr11:101,246,028...101,259,546
JBrowse link
G Rgs3 regulator of G-protein signaling 3 affects expression EXP diethyl malate affects the expression of RGS3 mRNA CTD PMID:24814887 NCBI chr 4:62,559,835...62,703,019
Ensembl chr 4:62,559,847...62,704,001
JBrowse link
G Runx1t1 RUNX1 translocation partner 1 affects expression EXP diethyl malate affects the expression of RUNX1T1 mRNA CTD PMID:24814887 NCBI chr 4:13,742,628...13,895,056
Ensembl chr 4:13,743,436...13,893,649
JBrowse link
G Sema3b sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B affects expression EXP diethyl malate affects the expression of SEMA3B mRNA CTD PMID:24814887 NCBI chr 9:107,597,674...107,609,241
Ensembl chr 9:107,597,674...107,609,229
JBrowse link
G Sema4g sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G affects expression EXP diethyl malate affects the expression of SEMA4G mRNA CTD PMID:24814887 NCBI chr19:44,988,743...45,003,397
Ensembl chr19:44,989,101...45,003,397
JBrowse link
G Sema5a sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A affects expression EXP diethyl malate affects the expression of SEMA5A mRNA CTD PMID:24814887 NCBI chr15:32,244,813...32,696,341
Ensembl chr15:32,244,810...32,696,341
JBrowse link
G Stat1 signal transducer and activator of transcription 1 affects expression EXP diethyl malate affects the expression of STAT1 mRNA CTD PMID:24814887 NCBI chr 1:52,119,438...52,161,865
Ensembl chr 1:52,119,440...52,161,865
JBrowse link
G Tgfb2 transforming growth factor, beta 2 affects expression
multiple interactions
EXP diethyl malate affects the expression of TGFB2 mRNA
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of TGFB2 mRNA]
CTD PMID:24814887 NCBI chr 1:186,622,787...186,709,697
Ensembl chr 1:186,622,792...186,705,989
JBrowse link
G Thbs1 thrombospondin 1 affects expression EXP diethyl malate affects the expression of THBS1 mRNA CTD PMID:24814887 NCBI chr 2:118,111,876...118,127,133
Ensembl chr 2:118,111,876...118,127,133
JBrowse link
G Thbs2 thrombospondin 2 affects expression EXP diethyl malate affects the expression of THBS2 mRNA CTD PMID:24814887 NCBI chr17:14,665,500...14,694,262
Ensembl chr17:14,665,500...14,694,235
JBrowse link
G Tnc tenascin C affects expression EXP diethyl malate affects the expression of TNC mRNA CTD PMID:24814887 NCBI chr 4:63,959,785...64,047,015
Ensembl chr 4:63,959,785...64,047,015
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) affects expression EXP diethyl malate affects the expression of TNFRSF11B mRNA CTD PMID:24814887 NCBI chr15:54,250,619...54,278,484
Ensembl chr15:54,250,619...54,278,484
JBrowse link
G Tnnt1 troponin T1, skeletal, slow affects expression EXP diethyl malate affects the expression of TNNT1 mRNA CTD PMID:24814887 NCBI chr 7:4,504,569...4,515,975
Ensembl chr 7:4,504,570...4,516,382
JBrowse link
G Tslp thymic stromal lymphopoietin affects expression EXP diethyl malate affects the expression of TSLP mRNA CTD PMID:24814887 NCBI chr18:32,815,383...32,819,799
Ensembl chr18:32,815,383...32,819,797
JBrowse link
diethyl maleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 increases expression EXP diethyl maleate results in increased expression of ABCC2 mRNA CTD PMID:25270620 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740
JBrowse link
G Abhd4 abhydrolase domain containing 4 increases expression EXP diethyl maleate results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr14:54,254,129...54,269,169
Ensembl chr14:54,254,188...54,270,637
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha decreases expression EXP diethyl maleate results in decreased expression of ACACA mRNA CTD PMID:25270620 NCBI chr11:84,129,635...84,401,651
Ensembl chr11:84,129,672...84,401,651
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions ISO diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]] CTD PMID:17134953 NCBI chr11:116,171,883...116,199,045
Ensembl chr11:116,171,888...116,199,045
JBrowse link
G Acy3 aspartoacylase (aminoacylase) 3 decreases expression ISO diethyl maleate results in decreased expression of ACY3 mRNA CTD PMID:21161181 NCBI chr19:3,986,570...3,990,007
Ensembl chr19:3,986,570...3,990,007
JBrowse link
G Adora3 adenosine A3 receptor decreases expression ISO diethyl maleate results in decreased expression of ADORA3 mRNA CTD PMID:21161181 NCBI chr 3:105,904,421...105,908,928
Ensembl chr 3:105,870,858...105,908,926
JBrowse link
G Afp alpha fetoprotein increases expression EXP diethyl maleate results in increased expression of AFP mRNA CTD PMID:25270620 NCBI chr 5:90,490,714...90,508,907
Ensembl chr 5:90,490,737...90,508,907
JBrowse link
G Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 increases expression EXP diethyl maleate results in increased expression of AHCYL1 mRNA CTD PMID:25270620 NCBI chr 3:107,663,120...107,696,560
Ensembl chr 3:107,663,118...107,696,560
JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) increases expression ISO diethyl maleate results in increased expression of AKR1A1 protein CTD PMID:21161181 NCBI chr 4:116,636,510...116,651,674
Ensembl chr 4:116,636,510...116,651,680
JBrowse link
G Akr1c19 aldo-keto reductase family 1, member C19 increases expression EXP diethyl maleate results in increased expression of AKR1C19 mRNA CTD PMID:25270620 NCBI chr13:4,233,503...4,248,361
Ensembl chr13:4,228,700...4,252,843
JBrowse link
G Akr1c21 aldo-keto reductase family 1, member C21 increases expression ISO diethyl maleate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr13:4,574,075...4,586,543
Ensembl chr13:4,574,075...4,586,541
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 affects reduction EXP diethyl maleate affects the reduction of ALDH1A1 protein CTD PMID:19843705 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression ISO diethyl maleate results in decreased expression of ALDH1B1 mRNA CTD PMID:21161181 NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial decreases reduction
increases expression
decreases expression
EXP
ISO
diethyl maleate results in decreased reduction of ALDH2 protein
diethyl maleate results in increased expression of ALDH2 protein
diethyl maleate results in decreased expression of ALDH2 protein
CTD PMID:19843705 PMID:21161181 NCBI chr 5:121,566,027...121,593,824
Ensembl chr 5:121,566,027...121,593,824
JBrowse link
G Aldob aldolase B, fructose-bisphosphate decreases expression ISO diethyl maleate results in decreased expression of ALDOB protein CTD PMID:21161181 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression ISO diethyl maleate results in decreased expression of AMIGO2 mRNA CTD PMID:21161181 NCBI chr15:97,244,074...97,247,287
Ensembl chr15:97,244,125...97,247,287
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO diethyl maleate results in decreased expression of ANGPTL2 mRNA CTD PMID:21161181 NCBI chr 2:33,215,951...33,247,725
Ensembl chr 2:33,216,069...33,247,717
JBrowse link
G Ankrd46 ankyrin repeat domain 46 decreases expression ISO diethyl maleate results in decreased expression of ANKRD46 mRNA CTD PMID:21161181 NCBI chr15:36,477,668...36,496,791
Ensembl chr15:36,477,668...36,496,820
JBrowse link
G Anln anillin, actin binding protein increases expression ISO diethyl maleate results in increased expression of ANLN mRNA CTD PMID:21161181 NCBI chr 9:22,331,214...22,389,211
Ensembl chr 9:22,332,012...22,389,188
JBrowse link
G Anxa3 annexin A3 decreases expression ISO diethyl maleate results in decreased expression of ANXA3 mRNA CTD PMID:21161181 NCBI chr 5:96,793,385...96,845,968
Ensembl chr 5:96,793,339...96,845,966
JBrowse link
G Ap3m2 adaptor-related protein complex 3, mu 2 subunit decreases expression ISO diethyl maleate results in decreased expression of AP3M2 mRNA CTD PMID:21161181 NCBI chr 8:22,787,354...22,807,292
Ensembl chr 8:22,787,354...22,805,622
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO diethyl maleate results in increased expression of APAF1 mRNA CTD PMID:11875189 NCBI chr10:90,989,311...91,082,743
Ensembl chr10:90,989,311...91,082,770
JBrowse link
G Aplp1 amyloid beta (A4) precursor-like protein 1 decreases expression EXP diethyl maleate results in decreased expression of APLP1 mRNA CTD PMID:25270620 NCBI chr 7:30,434,980...30,445,582
Ensembl chr 7:30,434,982...30,445,535
JBrowse link
G Apol6 apolipoprotein L 6 decreases expression ISO diethyl maleate results in decreased expression of APOL9A mRNA CTD PMID:21161181 NCBI chr15:77,045,050...77,057,108
Ensembl chr15:77,044,729...77,057,106
JBrowse link
G Apol9a apolipoprotein L 9a decreases expression ISO diethyl maleate results in decreased expression of APOL9A mRNA CTD PMID:21161181 NCBI chr15:77,403,789...77,411,080
Ensembl chr15:77,403,789...77,411,135
JBrowse link
G Arrdc2 arrestin domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of ARRDC2 mRNA CTD PMID:21161181 NCBI chr 8:70,835,129...70,839,720
Ensembl chr 8:70,835,129...70,839,720
JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression EXP diethyl maleate results in decreased expression of ARRDC4 mRNA CTD PMID:25270620 NCBI chr 7:68,736,994...68,749,238
Ensembl chr 7:68,736,995...68,749,241
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone increases expression ISO diethyl maleate results in increased expression of ASF1B mRNA CTD PMID:21161181 NCBI chr 8:83,955,694...83,970,195
Ensembl chr 8:83,955,507...83,970,197
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 decreases expression EXP diethyl maleate results in decreased expression of ASXL1 mRNA CTD PMID:25270620 NCBI chr 2:153,345,830...153,404,007
Ensembl chr 2:153,345,829...153,404,007
JBrowse link
G Atm ataxia telangiectasia mutated increases expression ISO diethyl maleate results in increased expression of ATM mRNA CTD PMID:11875189 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740
JBrowse link
G Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit increases expression ISO diethyl maleate results in increased expression of ATP5F1B protein CTD PMID:21161181 NCBI chr10:128,083,307...128,090,388
Ensembl chr10:128,083,273...128,090,391
JBrowse link
G Aurka aurora kinase A increases expression
decreases expression
ISO
EXP
diethyl maleate results in increased expression of AURKA mRNA
diethyl maleate results in decreased expression of AURKA mRNA
CTD PMID:21161181 PMID:25270620 NCBI chr 2:172,356,190...172,370,886
Ensembl chr 2:172,356,190...172,370,535
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions EXP [diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of BCL2 mRNA CTD PMID:22564015 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b decreases expression ISO diethyl maleate results in decreased expression of BCL2A1 mRNA CTD PMID:21161181 NCBI chr 9:89,199,273...89,207,838
Ensembl chr 9:89,199,209...89,207,827
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 decreases expression EXP diethyl maleate results in decreased expression of BCL3 mRNA CTD PMID:25270620 NCBI chr 7:19,808,462...19,822,824
Ensembl chr 7:19,808,462...19,822,770
JBrowse link
G Bcl6b B cell CLL/lymphoma 6, member B decreases expression ISO diethyl maleate results in decreased expression of BCL6B mRNA CTD PMID:21161181 NCBI chr11:70,224,127...70,229,798
Ensembl chr11:70,224,128...70,229,798
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 decreases expression ISO diethyl maleate results in decreased expression of BHLHE41 mRNA CTD PMID:21161181 NCBI chr 6:145,858,243...145,865,420
Ensembl chr 6:145,858,243...145,865,558
JBrowse link
G Bhmt betaine-homocysteine methyltransferase decreases expression ISO diethyl maleate results in decreased expression of BHMT mRNA CTD PMID:21161181 NCBI chr13:93,616,891...93,637,758
Ensembl chr13:93,616,675...93,637,961
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions EXP diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA] CTD PMID:12774022 NCBI chr 9:7,847,468...7,873,205
Ensembl chr 9:7,848,699...7,873,186
JBrowse link
G Blvrb biliverdin reductase B (flavin reductase (NADPH)) increases expression EXP diethyl maleate results in increased expression of BLVRB mRNA CTD PMID:25270620 NCBI chr 7:27,447,978...27,465,981
Ensembl chr 7:27,447,978...27,466,144
JBrowse link
G Bmf BCL2 modifying factor decreases expression ISO diethyl maleate results in decreased expression of BMF mRNA CTD PMID:21161181 NCBI chr 2:118,528,757...118,549,686
Ensembl chr 2:118,528,757...118,549,687
JBrowse link
G Brip1 BRCA1 interacting protein C-terminal helicase 1 increases expression ISO diethyl maleate results in increased expression of BRIP1 mRNA CTD PMID:21161181 NCBI chr11:86,058,136...86,201,215
Ensembl chr11:86,058,138...86,201,193
JBrowse link
G Btbd2 BTB (POZ) domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of BTBD2 mRNA CTD PMID:21161181 NCBI chr10:80,642,623...80,656,494
Ensembl chr10:80,642,617...80,657,071
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression
decreases expression
multiple interactions
EXP diethyl maleate results in increased expression of BTG2 mRNA
diethyl maleate results in decreased expression of BTG2 mRNA
NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]
CTD PMID:22003191 PMID:25270620 NCBI chr 1:134,074,865...134,079,155
Ensembl chr 1:134,075,170...134,079,120
JBrowse link
G C6 complement component 6 decreases expression ISO diethyl maleate results in decreased expression of C6 mRNA CTD PMID:21161181 NCBI chr15:4,727,067...4,804,045
Ensembl chr15:4,727,175...4,814,967
JBrowse link
G Casp2 caspase 2 increases expression ISO diethyl maleate results in increased expression of CASP2 mRNA CTD PMID:11875189 NCBI chr 6:42,264,902...42,282,508
Ensembl chr 6:42,264,985...42,282,508
JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
ISO diethyl maleate results in increased expression of CASP3 mRNA
diethyl maleate results in increased cleavage of CASP3 protein
CTD PMID:11875189 PMID:21105742 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 increases expression ISO diethyl maleate results in increased expression of CASP9 mRNA CTD PMID:11875189 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase decreases expression ISO diethyl maleate results in decreased expression of CAT protein CTD PMID:21161181 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression EXP diethyl maleate results in increased expression of CBR1 mRNA CTD PMID:25270620 NCBI chr16:93,607,837...93,610,349
Ensembl chr16:93,605,853...93,610,505
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression
multiple interactions
ISO
EXP
diethyl maleate results in increased expression of CBR3 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diethyl maleate results in increased expression of CBR3 mRNA]
CTD PMID:20806931 PMID:25270620 NCBI chr16:93,683,219...93,690,991
Ensembl chr16:93,683,215...93,690,990
JBrowse link
G Ccdc50 coiled-coil domain containing 50 decreases expression EXP diethyl maleate results in decreased expression of CCDC50 mRNA CTD PMID:25270620 NCBI chr16:27,387,065...27,452,218
Ensembl chr16:27,388,869...27,452,218
JBrowse link
G Ccna1 cyclin A1 decreases expression ISO diethyl maleate results in decreased expression of CCNA1 mRNA CTD PMID:11875189 NCBI chr 3:55,045,469...55,057,634
Ensembl chr 3:55,045,469...55,055,501
JBrowse link
G Ccna2 cyclin A2 increases expression ISO diethyl maleate results in increased expression of CCNA2 mRNA CTD PMID:21161181 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150
JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression
ISO
EXP
diethyl maleate results in decreased expression of CCND1 mRNA
diethyl maleate results in increased expression of CCND1 mRNA
CTD PMID:11875189 PMID:21161181 PMID:25270620 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G Ccne2 cyclin E2 increases expression ISO diethyl maleate results in increased expression of CCNE2 mRNA CTD PMID:21161181 NCBI chr 4:11,190,433...11,204,779
Ensembl chr 4:11,191,351...11,204,779
JBrowse link
G Ccnk cyclin K decreases expression ISO diethyl maleate results in decreased expression of CCNK mRNA CTD PMID:11875189 NCBI chr12:108,179,308...108,203,359
Ensembl chr12:108,179,579...108,203,359
JBrowse link
G Cd80 CD80 antigen multiple interactions
increases expression
ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein
diethyl maleate results in increased expression of CD80 protein
CTD PMID:31958493 NCBI chr16:38,457,430...38,495,958
Ensembl chr16:38,455,561...38,496,335
JBrowse link
G Cd86 CD86 antigen multiple interactions
increases expression
ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; bisindolylmaleimide I inhibits the reaction [diethyl maleate results in increased expression of CD86 protein] CTD PMID:24136171 PMID:31958493 NCBI chr16:36,568,956...36,666,158
Ensembl chr16:36,603,869...36,666,081
JBrowse link
G Cdc25a cell division cycle 25A increases expression ISO diethyl maleate results in increased expression of CDC25A mRNA CTD PMID:21161181 NCBI chr 9:109,875,518...109,893,895
Ensembl chr 9:109,875,579...109,893,895
JBrowse link
G Cdca2 cell division cycle associated 2 increases expression ISO diethyl maleate results in increased expression of CDCA2 mRNA CTD PMID:21161181 NCBI chr14:67,673,180...67,715,841
Ensembl chr14:67,676,331...67,715,841
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression ISO diethyl maleate results in increased expression of CDCA3 mRNA CTD PMID:21161181 NCBI chr 6:124,829,530...124,833,701
Ensembl chr 6:124,829,547...124,833,701
JBrowse link
G Cdca8 cell division cycle associated 8 increases expression ISO diethyl maleate results in increased expression of CDCA8 mRNA CTD PMID:21161181 NCBI chr 4:124,918,465...124,936,917
Ensembl chr 4:124,918,465...124,939,311
JBrowse link
G Cdh11 cadherin 11 decreases expression ISO diethyl maleate results in decreased expression of CDH11 mRNA CTD PMID:21161181 NCBI chr 8:102,632,095...102,785,493
Ensembl chr 8:102,632,095...102,785,642
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) increases expression
multiple interactions
ISO diethyl maleate results in increased expression of CDKN1A mRNA; diethyl maleate results in increased expression of CDKN1A protein
TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]
CTD PMID:11875189 PMID:27982581 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cds2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 increases expression EXP diethyl maleate results in increased expression of CDS2 mRNA CTD PMID:25270620 NCBI chr 2:132,253,338...132,312,050
Ensembl chr 2:132,263,148...132,312,050
JBrowse link
G Ces1d carboxylesterase 1D increases reduction
decreases expression
EXP
ISO
diethyl maleate results in increased reduction of CES1D protein
diethyl maleate results in decreased expression of CES1D protein
CTD PMID:19843705 PMID:21161181 NCBI chr 8:93,166,072...93,197,804
Ensembl chr 8:93,166,068...93,197,838
JBrowse link
G Ces2a carboxylesterase 2A increases reduction EXP diethyl maleate results in increased reduction of CES2A protein CTD PMID:19843705 NCBI chr 8:104,734,003...104,741,634
Ensembl chr 8:104,734,003...104,741,634
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO diethyl maleate results in decreased expression of CFLAR mRNA CTD PMID:21161181 NCBI chr 1:58,711,311...58,758,884
Ensembl chr 1:58,711,508...58,758,884
JBrowse link
G Cidec cell death-inducing DFFA-like effector c decreases expression ISO diethyl maleate results in decreased expression of CIDEC mRNA CTD PMID:21161181 NCBI chr 6:113,424,634...113,435,760
Ensembl chr 6:113,424,634...113,435,760
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression ISO diethyl maleate results in decreased expression of CITED2 mRNA CTD PMID:21161181 NCBI chr10:17,723,228...17,725,674
Ensembl chr10:17,723,218...17,725,674
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression ISO diethyl maleate results in decreased expression of CITED4 mRNA CTD PMID:21161181 NCBI chr 4:120,666,563...120,667,820
Ensembl chr 4:120,666,572...120,667,820
JBrowse link
G Ckb creatine kinase, brain decreases reduction EXP diethyl maleate results in decreased reduction of CKB protein CTD PMID:19843705 NCBI chr12:111,669,355...111,672,338
Ensembl chr12:111,669,361...111,672,338
JBrowse link
G Cmpk2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial decreases expression ISO diethyl maleate results in decreased expression of CMPK2 mRNA CTD PMID:21161181 NCBI chr12:26,469,117...26,479,837
Ensembl chr12:26,469,204...26,479,837
JBrowse link
G Col1a1 collagen, type I, alpha 1 decreases expression ISO diethyl maleate results in decreased expression of COL1A1 mRNA CTD PMID:21161181 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Col3a1 collagen, type III, alpha 1 decreases expression EXP diethyl maleate results in decreased expression of COL3A1 mRNA CTD PMID:25270620 NCBI chr 1:45,311,538...45,349,706
Ensembl chr 1:45,311,538...45,349,706
JBrowse link
G Commd3 COMM domain containing 3 increases expression EXP diethyl maleate results in increased expression of COMMD3 mRNA CTD PMID:25270620 NCBI chr 2:18,672,435...18,676,231
Ensembl chr 2:18,672,384...18,676,231
JBrowse link
G Comt catechol-O-methyltransferase decreases expression ISO diethyl maleate results in decreased expression of COMT mRNA CTD PMID:21161181 NCBI chr16:18,406,882...18,426,716
Ensembl chr16:18,406,886...18,426,852
JBrowse link
G Cp ceruloplasmin decreases expression EXP diethyl maleate results in decreased expression of CP mRNA CTD PMID:25270620 NCBI chr 3:19,956,933...20,009,750
Ensembl chr 3:19,957,054...20,009,145
JBrowse link
G Crym crystallin, mu decreases expression ISO diethyl maleate results in decreased expression of CRYM mRNA CTD PMID:21161181 NCBI chr 7:120,186,380...120,201,989
Ensembl chr 7:120,186,380...120,202,111
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression ISO diethyl maleate results in decreased expression of CSRP1 mRNA CTD PMID:21161181 NCBI chr 1:135,720,063...135,752,229
Ensembl chr 1:135,720,061...135,752,232
JBrowse link
G Csrp3 cysteine and glycine-rich protein 3 decreases reduction EXP diethyl maleate results in decreased reduction of CSRP3 protein CTD PMID:19843705 NCBI chr 7:48,830,398...48,848,051
Ensembl chr 7:48,830,398...48,848,033
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 decreases expression ISO diethyl maleate results in decreased expression of CXCL10 mRNA CTD PMID:21161181 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889
JBrowse link
G Cxcl12 chemokine (C-X-C motif) ligand 12 decreases expression ISO diethyl maleate results in decreased expression of CXCL12 mRNA CTD PMID:21161181 NCBI chr 6:117,168,535...117,181,368
Ensembl chr 6:117,168,535...117,181,367
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases expression
multiple interactions
increases secretion
increases stability
ISO diethyl maleate results in increased expression of CXCL8 mRNA; diethyl maleate results in increased expression of CXCL8 protein
bisindolylmaleimide I inhibits the reaction [diethyl maleate results in increased expression of CXCL8 protein]
diethyl maleate results in increased secretion of CXCL8 protein
diethyl maleate results in increased stability of CXCL8 mRNA
CTD PMID:20491607 PMID:20541004 PMID:21920952 PMID:21969073 PMID:24136171 PMID:31958493 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 decreases expression ISO diethyl maleate results in decreased expression of CXCL9 mRNA CTD PMID:21161181 NCBI chr 5:92,321,331...92,328,079
Ensembl chr 5:92,321,347...92,328,079
JBrowse link
G Cyb5a cytochrome b5 type A (microsomal) increases expression EXP diethyl maleate results in increased expression of CYB5A mRNA CTD PMID:25270620 NCBI chr18:84,851,338...84,879,871
Ensembl chr18:84,838,704...84,879,871
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression ISO diethyl maleate results in decreased expression of CYP26B1 mRNA CTD PMID:21161181 NCBI chr 6:84,571,414...84,593,908
Ensembl chr 6:84,571,414...84,593,908
JBrowse link
G D17H6S56E-5 DNA segment, Chr 17, human D6S56E 5 decreases expression EXP diethyl maleate results in decreased expression of D17H6S56E-5 mRNA CTD PMID:25270620 NCBI chr17:34,996,678...35,000,774 JBrowse link
G Dbp D site albumin promoter binding protein decreases expression ISO diethyl maleate results in decreased expression of DBP mRNA CTD PMID:21161181 NCBI chr 7:45,705,100...45,710,203
Ensembl chr 7:45,705,088...45,710,203
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression EXP diethyl maleate results in increased expression of DDIT4L mRNA CTD PMID:25270620 NCBI chr 3:137,623,672...137,628,332
Ensembl chr 3:137,621,612...137,628,333
JBrowse link
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 decreases expression ISO diethyl maleate results in decreased expression of DHX58 mRNA CTD PMID:21161181 NCBI chr11:100,694,884...100,704,271
Ensembl chr11:100,694,884...100,704,271
JBrowse link
G Dnmbp dynamin binding protein decreases expression ISO diethyl maleate results in decreased expression of DNMBP mRNA CTD PMID:21161181 NCBI chr19:43,846,815...43,940,232
Ensembl chr19:43,846,821...43,940,191
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases reduction EXP diethyl maleate results in decreased reduction of DPYSL2 protein CTD PMID:19843705 NCBI chr14:66,802,864...66,911,041
Ensembl chr14:66,802,864...66,868,688
JBrowse link
G Dtx3l deltex 3-like, E3 ubiquitin ligase decreases expression ISO diethyl maleate results in decreased expression of DTX3L mRNA CTD PMID:21161181 NCBI chr16:35,926,515...35,939,027
Ensembl chr16:35,926,511...35,939,151
JBrowse link
G Dus3l dihydrouridine synthase 3-like (S. cerevisiae) decreases expression EXP diethyl maleate results in decreased expression of DUS3L mRNA CTD PMID:25270620 NCBI chr17:56,764,751...56,770,093
Ensembl chr17:56,764,757...56,770,093
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO diethyl maleate results in decreased expression of EEF2K mRNA CTD PMID:21161181 NCBI chr 7:120,842,642...120,907,219
Ensembl chr 7:120,842,831...120,907,450
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 decreases expression ISO diethyl maleate results in decreased expression of EIF2AK2 mRNA CTD PMID:21161181 NCBI chr17:78,850,504...78,882,572
Ensembl chr17:78,852,564...78,882,573
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression EXP diethyl maleate results in increased expression of ENTPD5 mRNA CTD PMID:25270620 NCBI chr12:84,373,875...84,409,029
Ensembl chr12:84,373,857...84,409,029
JBrowse link
G Eras ES cell-expressed Ras decreases expression EXP diethyl maleate results in decreased expression of ERAS mRNA CTD PMID:25270620 NCBI chr  X:7,924,276...7,928,607
Ensembl chr  X:7,924,276...7,928,607
JBrowse link
G Ercc6l excision repair cross-complementing rodent repair deficiency complementation group 6 like increases expression ISO diethyl maleate results in increased expression of ERCC6L mRNA CTD PMID:21161181 NCBI chr  X:102,142,820...102,157,091
Ensembl chr  X:102,141,716...102,157,091
JBrowse link
G Exo1 exonuclease 1 increases expression ISO diethyl maleate results in increased expression of EXO1 mRNA CTD PMID:21161181 NCBI chr 1:175,880,768...175,911,396
Ensembl chr 1:175,880,581...175,913,489
JBrowse link
G Fabp1 fatty acid binding protein 1, liver increases expression ISO diethyl maleate results in increased expression of FABP1 protein CTD PMID:21161181 NCBI chr 6:71,199,879...71,205,034
Ensembl chr 6:71,199,827...71,205,023
JBrowse link
G Fabp7 fatty acid binding protein 7, brain decreases expression ISO diethyl maleate results in decreased expression of FABP7 mRNA CTD PMID:21161181 NCBI chr10:57,784,923...57,788,450
Ensembl chr10:57,784,881...57,788,450
JBrowse link
G Fam126b family with sequence similarity 126, member B decreases expression ISO diethyl maleate results in decreased expression of FAM126B mRNA CTD PMID:21161181 NCBI chr 1:58,522,806...58,586,333
Ensembl chr 1:58,522,806...58,586,323
JBrowse link
G Fasn fatty acid synthase decreases expression ISO diethyl maleate results in decreased expression of FASN mRNA CTD PMID:21161181 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547
JBrowse link
G Fbn1 fibrillin 1 decreases expression ISO diethyl maleate results in decreased expression of FBN1 mRNA CTD PMID:21161181 NCBI chr 2:125,300,594...125,506,485
Ensembl chr 2:125,300,594...125,507,993
JBrowse link
G Fbp1 fructose bisphosphatase 1 decreases expression ISO diethyl maleate results in decreased expression of FBP1 protein CTD PMID:21161181 NCBI chr13:62,864,753...62,888,298
Ensembl chr13:62,864,753...62,888,282
JBrowse link
G Fgf17 fibroblast growth factor 17 decreases expression EXP diethyl maleate results in decreased expression of FGF17 mRNA CTD PMID:25270620 NCBI chr14:70,636,203...70,642,268
Ensembl chr14:70,636,203...70,642,268
JBrowse link
G Fgg fibrinogen gamma chain decreases expression EXP diethyl maleate results in decreased expression of FGG mRNA CTD PMID:25270620 NCBI chr 3:83,007,724...83,015,056
Ensembl chr 3:83,007,724...83,015,049
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases expression ISO diethyl maleate results in decreased expression of FGR mRNA CTD PMID:21161181 NCBI chr 4:132,974,095...133,001,893
Ensembl chr 4:132,974,095...133,001,910
JBrowse link
G Fndc3b fibronectin type III domain containing 3B decreases expression EXP diethyl maleate results in decreased expression of FNDC3B mRNA CTD PMID:25270620 NCBI chr 3:27,416,135...27,711,307
Ensembl chr 3:27,416,162...27,711,307
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression EXP diethyl maleate results in increased expression of FOS mRNA CTD PMID:10915739 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G G6pc glucose-6-phosphatase, catalytic decreases expression EXP diethyl maleate results in decreased expression of G6PC mRNA CTD PMID:25270620 NCBI chr11:101,367,716...101,377,903
Ensembl chr11:101,367,561...101,377,903
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked increases activity ISO diethyl maleate results in increased activity of G6PD protein CTD PMID:3099627 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Gab1 growth factor receptor bound protein 2-associated protein 1 decreases expression EXP diethyl maleate results in decreased expression of GAB1 mRNA CTD PMID:25270620 NCBI chr 8:80,764,431...80,880,519
Ensembl chr 8:80,764,438...80,880,519
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases reduction EXP diethyl maleate results in increased reduction of GAPDH protein CTD PMID:19843705 NCBI chr 6:125,161,852...125,166,467
Ensembl chr 6:125,161,715...125,166,467
JBrowse link
G Gba2 glucosidase beta 2 decreases expression EXP diethyl maleate results in decreased expression of GBA2 mRNA CTD PMID:25270620 NCBI chr 4:43,566,928...43,578,886
Ensembl chr 4:43,566,928...43,578,873
JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO diethyl maleate results in decreased expression of GBP2 mRNA CTD PMID:21161181 NCBI chr 3:142,620,663...142,638,008
Ensembl chr 3:142,620,602...142,638,008
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases activity
increases expression
EXP
ISO
diethyl maleate results in increased activity of GCLC protein
diethyl maleate results in increased expression of GCLC mRNA; diethyl maleate results in increased expression of GCLC protein
CTD PMID:10915739 PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO
EXP
diethyl maleate results in increased expression of GCLM mRNA; diethyl maleate results in increased expression of GCLM protein CTD PMID:10978506 PMID:15115889 PMID:21465251 PMID:25270620 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Glul glutamate-ammonia ligase (glutamine synthetase) decreases expression EXP diethyl maleate results in decreased expression of GLUL mRNA CTD PMID:25270620 NCBI chr 1:153,899,929...153,909,723
Ensembl chr 1:153,899,944...153,909,723
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial decreases expression ISO diethyl maleate results in decreased expression of GOT2 protein CTD PMID:21161181 NCBI chr 8:95,864,133...95,888,401
Ensembl chr 8:95,864,134...95,888,547
JBrowse link
G Gpihbp1 GPI-anchored HDL-binding protein 1 decreases expression EXP diethyl maleate results in decreased expression of GPIHBP1 mRNA CTD PMID:25270620 NCBI chr15:75,596,630...75,598,213
Ensembl chr15:75,596,628...75,599,481
JBrowse link
G Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) decreases expression ISO diethyl maleate results in decreased expression of GRIA3 mRNA CTD PMID:21161181 NCBI chr  X:41,400,819...41,678,601
Ensembl chr  X:41,400,854...41,678,601
JBrowse link
G Gsn gelsolin decreases reduction EXP diethyl maleate results in decreased reduction of GSN protein CTD PMID:19843705 NCBI chr 2:35,256,359...35,307,902
Ensembl chr 2:35,256,380...35,307,892
JBrowse link
G Gsr glutathione reductase increases expression EXP diethyl maleate results in increased expression of GSR mRNA CTD PMID:25270620 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gss glutathione synthetase increases expression ISO diethyl maleate results in increased expression of GSS mRNA CTD PMID:10978506 NCBI chr 2:155,563,181...155,592,810
Ensembl chr 2:155,563,181...155,592,810
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) increases expression ISO diethyl maleate results in increased expression of GSTA5 protein CTD PMID:9794803 NCBI chr 9:78,230,669...78,242,683
Ensembl chr 9:78,230,656...78,242,684
JBrowse link
G Gsta2 glutathione S-transferase, alpha 2 (Yc2) increases expression ISO diethyl maleate results in increased expression of GSTA3 protein CTD PMID:9794803 NCBI chr 9:78,331,018...78,347,192
Ensembl chr 9:78,331,018...78,355,788
JBrowse link
G Gsta3 glutathione S-transferase, alpha 3 increases expression EXP diethyl maleate results in increased expression of GSTA2 mRNA CTD PMID:25270620 NCBI chr 1:21,240,565...21,265,575
Ensembl chr 1:21,240,589...21,265,661
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions EXP [diethyl maleate results in decreased abundance of Glutathione] which results in decreased expression of GSTK1 mRNA CTD PMID:22564015 NCBI chr 6:42,245,935...42,250,441
Ensembl chr 6:42,245,935...42,250,447
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 decreases expression ISO diethyl maleate results in decreased expression of GSTM1 protein CTD PMID:21161181 NCBI chr 3:108,012,250...108,017,973
Ensembl chr 3:108,012,255...108,017,973
JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression EXP diethyl maleate results in increased expression of GSTO1 mRNA CTD PMID:25270620 NCBI chr19:47,854,973...47,864,790
Ensembl chr19:47,854,970...47,864,790
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression ISO diethyl maleate results in increased expression of GSTP1 protein CTD PMID:9794803 NCBI chr19:4,035,411...4,037,912
Ensembl chr19:4,035,407...4,037,985
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 increases expression ISO diethyl maleate results in increased expression of GSTT1 protein CTD PMID:9794803 NCBI chr10:75,783,813...75,798,584
Ensembl chr10:75,783,813...75,798,584
JBrowse link
G Gtse1 G two S phase expressed protein 1 increases expression ISO diethyl maleate results in increased expression of GTSE1 mRNA CTD PMID:21161181 NCBI chr15:85,859,691...85,876,573
Ensembl chr15:85,859,745...85,876,573
JBrowse link
G H2-T23 histocompatibility 2, T region locus 23 decreases expression ISO diethyl maleate results in decreased expression of RT1-S3 mRNA CTD PMID:21161181 NCBI chr17:36,029,977...36,032,701
Ensembl chr17:36,029,773...36,032,855
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) increases expression EXP diethyl maleate results in increased expression of H6PD mRNA CTD PMID:25270620 NCBI chr 4:149,979,474...150,009,023
Ensembl chr 4:149,979,475...150,009,023
JBrowse link
G Helb helicase (DNA) B decreases expression EXP diethyl maleate results in decreased expression of HELB mRNA CTD PMID:25270620 NCBI chr10:120,083,608...120,113,010
Ensembl chr10:120,083,608...120,112,987
JBrowse link
G Hes6 hairy and enhancer of split 6 decreases expression ISO diethyl maleate results in decreased expression of HES6 mRNA CTD PMID:21161181 NCBI chr 1:91,411,483...91,414,038
Ensembl chr 1:91,411,483...91,414,038
JBrowse link
G Hjurp Holliday junction recognition protein increases expression ISO diethyl maleate results in increased expression of HJURP mRNA CTD PMID:21161181 NCBI chr 1:88,258,856...88,277,644
Ensembl chr 1:88,262,471...88,277,633
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO
EXP
diethyl maleate results in increased expression of HMOX1 mRNA CTD PMID:20491607 PMID:25270620 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases reduction EXP diethyl maleate results in decreased reduction of HNRNPH1 protein CTD PMID:19843705 NCBI chr11:50,375,257...50,386,528
Ensembl chr11:50,376,990...50,386,528
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression ISO diethyl maleate results in decreased expression of HSD17B2 mRNA CTD PMID:21161181 NCBI chr 8:117,700,982...117,759,030
Ensembl chr 8:117,701,904...117,759,027
JBrowse link
G Hspa5 heat shock protein 5 decreases reduction EXP diethyl maleate results in decreased reduction of HSPA5 protein CTD PMID:19843705 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Hspa8 heat shock protein 8 increases reduction EXP diethyl maleate results in increased reduction of HSPA8 protein CTD PMID:19843705 NCBI chr 9:40,801,276...40,805,202
Ensembl chr 9:40,800,984...40,810,087
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression EXP diethyl maleate results in increased expression of HTATIP2 mRNA CTD PMID:25270620 NCBI chr 7:49,759,045...49,774,000
Ensembl chr 7:49,759,115...49,773,975
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP diethyl maleate results in decreased expression of ICAM1 mRNA CTD PMID:25270620 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression EXP diethyl maleate results in decreased expression of ID3 mRNA CTD PMID:25270620 NCBI chr 4:136,143,822...136,145,392
Ensembl chr 4:136,143,497...136,145,755
JBrowse link
G Id4 inhibitor of DNA binding 4 decreases expression EXP diethyl maleate results in decreased expression of ID4 mRNA CTD PMID:25270620 NCBI chr13:48,261,116...48,266,028
Ensembl chr13:48,261,228...48,266,026
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO diethyl maleate results in decreased expression of IFIT3 mRNA CTD PMID:21161181 NCBI chr19:34,583,119...34,588,982
Ensembl chr19:34,583,531...34,588,731
JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon decreases expression EXP diethyl maleate results in decreased expression of IKBKE mRNA CTD PMID:25270620 NCBI chr 1:131,254,600...131,279,601
Ensembl chr 1:131,254,343...131,279,606
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma increases expression EXP diethyl maleate results in increased expression of IKBKG mRNA CTD PMID:25270620 NCBI chr  X:74,393,233...74,456,792
Ensembl chr  X:74,393,290...74,453,854
JBrowse link
G Il10 interleukin 10 increases secretion ISO diethyl maleate results in increased secretion of IL10 protein CTD PMID:31958493 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il18 interleukin 18 increases expression ISO diethyl maleate results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein CTD PMID:31958493 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Inhbb inhibin beta-B decreases expression EXP diethyl maleate results in decreased expression of INHBB mRNA CTD PMID:25270620 NCBI chr 1:119,415,463...119,422,248
Ensembl chr 1:119,415,465...119,422,248
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression ISO diethyl maleate results in decreased expression of INMT mRNA CTD PMID:21161181 NCBI chr 6:55,170,627...55,174,990
Ensembl chr 6:55,170,626...55,175,043
JBrowse link
G Ints7 integrator complex subunit 7 decreases expression EXP diethyl maleate results in decreased expression of INTS7 mRNA CTD PMID:25270620 NCBI chr 1:191,575,540...191,623,690
Ensembl chr 1:191,575,636...191,623,688
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO diethyl maleate results in decreased expression of IRF7 mRNA CTD PMID:21161181 NCBI chr 7:141,263,183...141,266,499
Ensembl chr 7:141,262,706...141,266,481
JBrowse link
G Irf9 interferon regulatory factor 9 decreases expression ISO diethyl maleate results in decreased expression of IRF9 mRNA CTD PMID:21161181 NCBI chr14:55,603,985...55,610,030
Ensembl chr14:55,603,571...55,610,030
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 decreases expression ISO diethyl maleate results in decreased expression of IRGM mRNA CTD PMID:21161181 NCBI chr11:48,865,245...48,871,420
Ensembl chr11:48,861,968...48,871,683
JBrowse link
G Itgal integrin alpha L decreases expression ISO diethyl maleate results in decreased expression of ITGAL mRNA CTD PMID:21161181 NCBI chr 7:127,296,139...127,335,137
Ensembl chr 7:127,296,260...127,335,138
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression EXP diethyl maleate results in decreased expression of ITIH3 mRNA CTD PMID:25270620 NCBI chr14:30,908,572...30,923,787
Ensembl chr14:30,908,572...30,923,760
JBrowse link
G Itih4 inter alpha-trypsin inhibitor, heavy chain 4 decreases expression EXP diethyl maleate results in decreased expression of ITIH4 mRNA CTD PMID:25270620 NCBI chr14:30,886,476...30,901,986
Ensembl chr14:30,886,476...30,902,353
JBrowse link
G Jam3 junction adhesion molecule 3 decreases expression ISO diethyl maleate results in decreased expression of JAM3 mRNA CTD PMID:21161181 NCBI chr 9:27,097,384...27,155,421
Ensembl chr 9:27,097,384...27,155,421
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression
increases phosphorylation
EXP pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]
diethyl maleate results in increased expression of JUN mRNA
CTD PMID:10915739 PMID:12774022 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kcne3 potassium voltage-gated channel, Isk-related subfamily, gene 3 decreases expression EXP diethyl maleate results in decreased expression of KCNE3 mRNA CTD PMID:25270620 NCBI chr 7:100,176,507...100,184,869
Ensembl chr 7:100,176,502...100,184,869
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 increases expression ISO diethyl maleate results in increased expression of KEAP1 protein CTD PMID:27358234 NCBI chr 9:21,229,730...21,239,332
Ensembl chr 9:21,229,730...21,239,361
JBrowse link
G Kifc5b kinesin family member C5B increases expression ISO diethyl maleate results in increased expression of KIFC1 mRNA CTD PMID:21161181 NCBI chr17:26,917,091...26,932,579
Ensembl chr17:26,917,091...26,932,583
JBrowse link
G Klf10 Kruppel-like factor 10 decreases expression ISO
EXP
diethyl maleate results in decreased expression of KLF10 mRNA CTD PMID:21161181 PMID:25270620 NCBI chr15:38,291,464...38,300,711
Ensembl chr15:38,291,463...38,300,706
JBrowse link
G Krt75 keratin 75 increases reduction EXP diethyl maleate results in increased reduction of KRT75 protein CTD PMID:19843705 NCBI chr15:101,563,343...101,573,904
Ensembl chr15:101,563,345...101,573,904
JBrowse link
G Lama1 laminin, alpha 1 decreases expression EXP diethyl maleate results in decreased expression of LAMA1 mRNA CTD PMID:25270620 NCBI chr17:67,697,127...67,822,645
Ensembl chr17:67,697,259...67,822,647
JBrowse link
G Lancl2 LanC (bacterial lantibiotic synthetase component C)-like 2 decreases expression EXP diethyl maleate results in decreased expression of LANCL2 mRNA CTD PMID:25270620 NCBI chr 6:57,702,455...57,739,449
Ensembl chr 6:57,702,540...57,739,439
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO diethyl maleate results in decreased expression of LDLR mRNA CTD PMID:21161181 NCBI chr 9:21,723,576...21,749,919
Ensembl chr 9:21,723,483...21,749,919
JBrowse link
G Lepr leptin receptor decreases expression ISO diethyl maleate results in decreased expression of LEPR mRNA CTD PMID:21161181 NCBI chr 4:101,717,137...101,815,352
Ensembl chr 4:101,717,404...101,815,352
JBrowse link
G Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein decreases expression ISO diethyl maleate results in decreased expression of LGALS3BP mRNA CTD PMID:21161181 NCBI chr11:118,392,747...118,401,959
Ensembl chr11:118,392,751...118,402,092
JBrowse link
G Lmnb1 lamin B1 increases expression ISO diethyl maleate results in increased expression of LMNB1 mRNA CTD PMID:21161181 NCBI chr18:56,707,813...56,753,424
Ensembl chr18:56,707,813...56,753,424
JBrowse link
G Lmo7 LIM domain only 7 decreases expression ISO diethyl maleate results in decreased expression of LMO7 mRNA CTD PMID:21161181 NCBI chr14:101,729,928...101,934,708
Ensembl chr14:101,729,957...101,934,710
JBrowse link
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 decreases expression ISO diethyl maleate results in decreased expression of LRIG3 mRNA CTD PMID:21161181 NCBI chr10:125,966,219...126,015,359
Ensembl chr10:125,966,168...126,015,359
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 increases expression ISO diethyl maleate results in increased expression of LRRN4 mRNA CTD PMID:21161181 NCBI chr 2:132,866,686...132,894,010
Ensembl chr 2:132,868,305...132,880,891
JBrowse link
G Lrtm2 leucine-rich repeats and transmembrane domains 2 decreases expression ISO diethyl maleate results in decreased expression of LRTM2 mRNA CTD PMID:21161181 NCBI chr 6:119,315,133...119,332,270
Ensembl chr 6:119,315,133...119,330,766
JBrowse link
G Ltc4s leukotriene C4 synthase decreases expression ISO diethyl maleate results in decreased expression of LTC4S mRNA CTD PMID:21161181 NCBI chr11:50,236,461...50,238,532
Ensembl chr11:50,236,461...50,238,616
JBrowse link
G Lum lumican decreases expression ISO diethyl maleate results in decreased expression of LUM mRNA CTD PMID:21161181 NCBI chr10:97,565,501...97,572,703
Ensembl chr10:97,565,128...97,572,703
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO diethyl maleate results in increased expression of MAFF mRNA CTD PMID:20491607 NCBI chr15:79,346,621...79,359,078
Ensembl chr15:79,346,621...79,359,076
JBrowse link
G Maoa monoamine oxidase A increases expression EXP diethyl maleate results in increased expression of MAOA mRNA CTD PMID:25270620 NCBI chr  X:16,619,698...16,687,812
Ensembl chr  X:16,619,698...16,687,818
JBrowse link
G Marveld1 MARVEL (membrane-associating) domain containing 1 decreases expression ISO diethyl maleate results in decreased expression of MARVELD1 mRNA CTD PMID:21161181 NCBI chr19:42,147,389...42,151,703
Ensembl chr19:42,147,400...42,151,703
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor increases expression ISO diethyl maleate results in increased expression of MCM10 mRNA CTD PMID:21161181 NCBI chr 2:4,990,724...5,012,791
Ensembl chr 2:4,989,714...5,012,791
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression ISO diethyl maleate results in increased expression of MCM4 mRNA CTD PMID:21161181 NCBI chr16:15,623,897...15,637,400
Ensembl chr16:15,623,897...15,637,400
JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic increases expression EXP diethyl maleate results in increased expression of ME1 mRNA CTD PMID:25270620 NCBI chr 9:86,581,363...86,695,914
Ensembl chr 9:86,581,371...86,695,953
JBrowse link
G Mfap4 microfibrillar-associated protein 4 decreases expression ISO diethyl maleate results in decreased expression of MFAP4 mRNA CTD PMID:21161181 NCBI chr11:61,485,431...61,488,708
Ensembl chr11:61,485,431...61,488,900
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO diethyl maleate results in decreased activity of MGMT protein CTD PMID:16950796 NCBI chr 7:136,894,463...137,128,193
Ensembl chr 7:136,894,614...137,130,266
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 increases expression ISO diethyl maleate results in increased expression of MKI67 mRNA CTD PMID:21161181 NCBI chr 7:135,689,784...135,716,450
Ensembl chr 7:135,689,784...135,716,361
JBrowse link
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 decreases expression ISO diethyl maleate results in decreased expression of MKNK2 mRNA CTD PMID:21161181 NCBI chr10:80,665,318...80,676,293
Ensembl chr10:80,665,327...80,678,112
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression EXP diethyl maleate results in increased expression of MMP12 mRNA CTD PMID:10216232 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO diethyl maleate results in decreased expression of MMP2 mRNA CTD PMID:21161181 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Msn moesin increases reduction EXP diethyl maleate results in increased reduction of MSN protein CTD PMID:19843705 NCBI chr  X:96,096,045...96,168,553
Ensembl chr  X:96,096,042...96,168,552
JBrowse link
G Mt2 metallothionein 2 increases expression ISO diethyl maleate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Mx2 MX dynamin-like GTPase 2 decreases expression ISO diethyl maleate results in decreased expression of MX1 mRNA CTD PMID:21161181 NCBI chr16:97,536,081...97,560,901
Ensembl chr16:97,535,308...97,560,900
JBrowse link
G Mybl2 myeloblastosis oncogene-like 2 increases expression ISO diethyl maleate results in increased expression of MYBL2 mRNA CTD PMID:21161181 NCBI chr 2:163,054,327...163,084,688
Ensembl chr 2:163,054,687...163,084,688
JBrowse link
G Mycn v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived decreases expression EXP diethyl maleate results in decreased expression of MYCN mRNA CTD PMID:25270620 NCBI chr12:12,936,093...12,941,836
Ensembl chr12:12,936,093...12,941,914
JBrowse link
G Nat8 N-acetyltransferase 8 (GCN5-related) decreases expression ISO diethyl maleate results in decreased expression of NAT8 mRNA CTD PMID:21161181 NCBI chr 6:85,830,387...85,836,857
Ensembl chr 6:85,830,388...85,832,082
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression ISO diethyl maleate results in increased expression of NCAPH mRNA CTD PMID:21161181 NCBI chr 2:127,103,809...127,133,954
Ensembl chr 2:127,103,809...127,133,954
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization
increases activity
increases expression
multiple interactions
decreases response to substance
EXP
ISO
diethyl maleate affects the localization of NFE2L2 protein
diethyl maleate results in increased activity of NFE2L2 protein
diethyl maleate results in increased expression of NFE2L2 protein
diethyl maleate binds to and results in increased activity of NFE2L2 protein; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
NFE2L2 results in decreased susceptibility to diethyl maleate
NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]
CTD PMID:12235164 PMID:20806931 PMID:21465251 PMID:22003191 PMID:27358234 PMID:27982581 PMID:30114225 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA] CTD PMID:12774022 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP
ISO
diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
Acetylcysteine inhibits the reaction [diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate]
CTD PMID:7532384 PMID:9918918 PMID:12774022 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO
EXP
diethyl maleate results in increased expression of NQO1 mRNA CTD PMID:20491607 PMID:25270620 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO diethyl maleate results in decreased expression of NR0B2 mRNA CTD PMID:21161181 NCBI chr 4:133,553,376...133,556,686
Ensembl chr 4:133,553,376...133,556,536
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO diethyl maleate results in decreased expression of NR1D1 mRNA CTD PMID:21161181 NCBI chr11:98,767,932...98,775,377
Ensembl chr11:98,767,932...98,775,333
JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO diethyl maleate results in decreased expression of NREP mRNA CTD PMID:21161181 NCBI chr18:33,437,019...33,464,365
Ensembl chr18:33,437,019...33,464,029
JBrowse link
G Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor decreases expression EXP diethyl maleate results in decreased expression of NSMF mRNA CTD PMID:25270620 NCBI chr 2:25,054,361...25,062,881
Ensembl chr 2:25,054,355...25,062,881
JBrowse link
G Ntf3 neurotrophin 3 decreases expression ISO diethyl maleate results in decreased expression of NTF3 mRNA CTD PMID:21161181 NCBI chr 6:126,101,412...126,166,772
Ensembl chr 6:126,101,412...126,166,910
JBrowse link
G Nup153 nucleoporin 153 multiple interactions
affects localization
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP153 protein]; diethyl maleate results in increased phosphorylation of and results in increased O-linked glycosylation of NUP153 protein CTD PMID:20041180 NCBI chr13:46,679,902...46,727,849
Ensembl chr13:46,679,905...46,727,940
JBrowse link
G Nup88 nucleoporin 88 multiple interactions
affects localization
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [diethyl maleate affects the localization of NUP88 protein]; [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] affects the reaction [diethyl maleate affects the localization of NUP88 protein]; diethyl maleate results in increased phosphorylation of and results in increased glycosylation of NUP88 protein CTD PMID:20041180 NCBI chr11:70,943,058...70,969,973
Ensembl chr11:70,943,058...70,969,973
JBrowse link
G Oaf out at first homolog decreases expression ISO diethyl maleate results in decreased expression of OAF mRNA CTD PMID:21161181 NCBI chr 9:43,221,278...43,239,816
Ensembl chr 9:43,221,235...43,239,911
JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 multiple interactions EXP [diethyl maleate results in decreased abundance of Glutathione] which results in increased expression of OGG1 mRNA CTD PMID:22564015 NCBI chr 6:113,326,972...113,334,877
Ensembl chr 6:113,326,972...113,335,068
JBrowse link
G Orc1 origin recognition complex, subunit 1 increases expression ISO diethyl maleate results in increased expression of ORC1 mRNA CTD PMID:21161181 NCBI chr 4:108,575,705...108,616,030
Ensembl chr 4:108,579,423...108,614,833
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 decreases expression ISO diethyl maleate results in decreased expression of P2RX7 mRNA CTD PMID:21161181 NCBI chr 5:122,643,927...122,692,336
Ensembl chr 5:122,643,911...122,691,432
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO diethyl maleate results in increased cleavage of PARP1 protein CTD PMID:21105742 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 decreases expression ISO diethyl maleate results in decreased expression of PBLD protein CTD PMID:21161181 NCBI chr10:63,060,625...63,077,964
Ensembl chr10:63,060,162...63,077,962
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO diethyl maleate results in decreased expression of PCNA mRNA CTD PMID:11875189 NCBI chr 2:132,249,286...132,253,180
Ensembl chr 2:132,249,162...132,253,314
JBrowse link
G Pdlim2 PDZ and LIM domain 2 decreases expression ISO diethyl maleate results in decreased expression of PDLIM2 mRNA CTD PMID:21161181 NCBI chr14:70,162,621...70,177,672
Ensembl chr14:70,164,218...70,177,681
JBrowse link
G Pdrg1 p53 and DNA damage regulated 1 increases expression EXP diethyl maleate results in increased expression of PDRG1 mRNA CTD PMID:25270620 NCBI chr 2:153,008,890...153,016,019
Ensembl chr 2:153,008,890...153,015,427
JBrowse link
G Per2 period circadian clock 2 decreases expression ISO diethyl maleate results in decreased expression of PER2 mRNA CTD PMID:21161181 NCBI chr 1:91,415,977...91,459,351
Ensembl chr 1:91,415,982...91,459,324
JBrowse link
G Per3 period circadian clock 3 decreases expression ISO diethyl maleate results in decreased expression of PER3 mRNA CTD PMID:21161181 NCBI chr 4:150,997,018...151,044,707
Ensembl chr 4:151,003,652...151,044,665
JBrowse link
G Pgd phosphogluconate dehydrogenase increases activity ISO diethyl maleate results in increased activity of PGD protein CTD PMID:3099627 NCBI chr 4:149,149,991...149,166,705
Ensembl chr 4:149,149,991...149,166,771
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 increases expression EXP diethyl maleate results in increased expression of PGRMC1 mRNA CTD PMID:25270620 NCBI chr  X:36,598,193...36,606,079
Ensembl chr  X:36,598,206...36,606,079
JBrowse link
G Pir pirin increases expression EXP diethyl maleate results in increased expression of PIR mRNA CTD PMID:25270620 NCBI chr  X:164,269,431...164,373,013
Ensembl chr  X:164,269,371...164,373,011
JBrowse link
G Pklr pyruvate kinase liver and red blood cell decreases expression ISO diethyl maleate results in decreased expression of PKLR mRNA CTD PMID:21161181 NCBI chr 3:89,136,122...89,146,815
Ensembl chr 3:89,136,142...89,146,784
JBrowse link
G Plat plasminogen activator, tissue increases expression
decreases expression
ISO
EXP
diethyl maleate results in increased expression of PLAT mRNA
diethyl maleate results in decreased expression of PLAT mRNA
CTD PMID:21161181 PMID:25270620 NCBI chr 8:22,757,722...22,782,848
Ensembl chr 8:22,757,727...22,782,844
JBrowse link
G Plek pleckstrin decreases expression ISO diethyl maleate results in decreased expression of PLEK mRNA CTD PMID:21161181 NCBI chr11:16,971,206...17,008,718
Ensembl chr11:16,971,206...17,052,381
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases activity
ISO diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]; resveratrol inhibits the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol inhibits the reaction [diethyl maleate results in decreased activity of PPARA protein]; resveratrol promotes the reaction [diethyl maleate inhibits the reaction [PPARA protein binds to ACOX1 promoter]]; resveratrol promotes the reaction [diethyl maleate results in decreased activity of PPARA protein] CTD PMID:17134953 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta decreases expression ISO diethyl maleate results in decreased expression of PPARGC1B mRNA CTD PMID:21161181 NCBI chr18:61,291,445...61,400,756
Ensembl chr18:61,298,136...61,400,431
JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression ISO diethyl maleate results in decreased expression of PPP1R3B mRNA CTD PMID:21161181 NCBI chr 8:35,375,694...35,388,139
Ensembl chr 8:35,375,739...35,388,139
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression ISO diethyl maleate results in decreased expression of PPP1R3C mRNA CTD PMID:21161181 NCBI chr19:36,731,731...36,736,604
Ensembl chr19:36,731,731...36,736,653
JBrowse link
G Prdm14 PR domain containing 14 decreases expression EXP diethyl maleate results in decreased expression of PRDM14 mRNA CTD PMID:25270620 NCBI chr 1:13,113,428...13,127,163
Ensembl chr 1:13,113,457...13,127,163
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression EXP
ISO
diethyl maleate results in increased expression of PRDX1 mRNA CTD PMID:9506838 NCBI chr 4:116,685,599...116,700,000
Ensembl chr 4:116,685,544...116,700,822
JBrowse link
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit decreases expression EXP diethyl maleate results in decreased expression of PRKAB1 mRNA CTD PMID:25270620 NCBI chr 5:116,013,586...116,024,503
Ensembl chr 5:116,013,586...116,024,508
JBrowse link
G Prkcb protein kinase C, beta affects expression ISO diethyl maleate affects the expression of PRKCB protein CTD PMID:31958493 NCBI chr 7:122,289,104...122,634,402
Ensembl chr 7:122,288,751...122,634,402
JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCD protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCD protein CTD PMID:11118818 NCBI chr14:30,595,353...30,626,414
Ensembl chr14:30,595,354...30,626,210
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCE protein]; diethyl maleate results in increased expression of and results in increased activity of PRKCE protein CTD PMID:11118818 NCBI chr17:86,167,785...86,657,919
Ensembl chr17:86,167,785...86,657,919
JBrowse link
G Prss8 protease, serine 8 (prostasin) decreases expression ISO diethyl maleate results in decreased expression of PRSS8 mRNA CTD PMID:21161181 NCBI chr 7:127,925,717...127,930,149
Ensembl chr 7:127,925,716...127,930,104
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression EXP diethyl maleate results in increased expression of PTGR1 mRNA CTD PMID:25270620 NCBI chr 4:58,965,590...58,987,131
Ensembl chr 4:58,965,439...58,987,119
JBrowse link
G Ptpn14 protein tyrosine phosphatase, non-receptor type 14 increases expression EXP diethyl maleate results in increased expression of PTPN14 mRNA CTD PMID:25270620 NCBI chr 1:189,728,216...189,876,695
Ensembl chr 1:189,728,268...189,876,695
JBrowse link
G Pus1 pseudouridine synthase 1 decreases expression EXP diethyl maleate results in decreased expression of PUS1 mRNA CTD PMID:25270620 NCBI chr 5:110,773,667...110,780,649
Ensembl chr 5:110,773,667...110,780,659
JBrowse link
G Rab27a RAB27A, member RAS oncogene family decreases expression ISO diethyl maleate results in decreased expression of RAB27A mRNA CTD PMID:21161181 NCBI chr 9:73,044,810...73,097,623
Ensembl chr 9:73,044,854...73,097,629
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] CTD PMID:20116392 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rnf114 ring finger protein 114 decreases expression EXP diethyl maleate results in decreased expression of RNF114 mRNA CTD PMID:25270620 NCBI chr 2:167,492,645...167,516,173
Ensembl chr 2:167,492,645...167,516,173
JBrowse link
G Rnf14 ring finger protein 14 increases expression EXP diethyl maleate results in increased expression of RNF14 mRNA CTD PMID:25270620 NCBI chr18:38,277,460...38,317,852
Ensembl chr18:38,284,537...38,317,849
JBrowse link
G Rrm2 ribonucleotide reductase M2 increases expression ISO diethyl maleate results in increased expression of RRM2 mRNA CTD PMID:21161181 NCBI chr12:24,708,254...24,714,146
Ensembl chr12:24,708,241...24,714,146
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO diethyl maleate results in decreased expression of RSAD2 mRNA CTD PMID:21161181 NCBI chr12:26,442,743...26,456,452
Ensembl chr12:26,442,746...26,456,452
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) decreases expression ISO diethyl maleate results in decreased expression of S100A9 mRNA CTD PMID:21161181 NCBI chr 3:90,692,630...90,695,721
Ensembl chr 3:90,692,632...90,695,721
JBrowse link
G Sash3 SAM and SH3 domain containing 3 decreases expression ISO diethyl maleate results in decreased expression of SASH3 mRNA CTD PMID:21161181 NCBI chr  X:48,146,436...48,161,565
Ensembl chr  X:48,146,436...48,161,565
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 decreases expression ISO diethyl maleate results in decreased expression of SCD1 mRNA CTD PMID:21161181 NCBI chr19:44,394,450...44,407,709
Ensembl chr19:44,394,455...44,407,879
JBrowse link
G Sds serine dehydratase decreases expression ISO diethyl maleate results in decreased expression of SDS mRNA CTD PMID:21161181 NCBI chr 5:120,476,547...120,483,932
Ensembl chr 5:120,476,526...120,483,932
JBrowse link
G Serpinb6b serine (or cysteine) peptidase inhibitor, clade B, member 6b decreases expression EXP diethyl maleate results in decreased expression of SERPINB6B mRNA CTD PMID:25270620 NCBI chr13:32,956,811...32,979,067
Ensembl chr13:32,965,209...32,979,067
JBrowse link
G Serpind1 serine (or cysteine) peptidase inhibitor, clade D, member 1 decreases expression EXP diethyl maleate results in decreased expression of SERPIND1 mRNA CTD PMID:25270620 NCBI chr16:17,331,371...17,343,574
Ensembl chr16:17,331,371...17,343,575
JBrowse link
G Sez6 seizure related gene 6 decreases expression ISO diethyl maleate results in decreased expression of SEZ6 mRNA CTD PMID:21161181 NCBI chr11:77,930,587...77,979,052
Ensembl chr11:77,930,800...77,979,048
JBrowse link
G Sfxn1 sideroflexin 1 decreases expression EXP diethyl maleate results in decreased expression of SFXN1 mRNA CTD PMID:25270620 NCBI chr13:54,071,656...54,108,346
Ensembl chr13:54,071,869...54,108,342
JBrowse link
G Six4 sine oculis-related homeobox 4 increases expression EXP diethyl maleate results in increased expression of SIX4 mRNA CTD PMID:25270620 NCBI chr12:73,099,609...73,114,031
Ensembl chr12:73,099,609...73,113,456
JBrowse link
G Slc16a6 solute carrier family 16 (monocarboxylic acid transporters), member 6 decreases expression EXP diethyl maleate results in decreased expression of SLC16A6 mRNA CTD PMID:25270620 NCBI chr11:109,450,855...109,473,598
Ensembl chr11:109,450,855...109,473,598
JBrowse link
G Slc1a4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 increases expression EXP diethyl maleate results in increased expression of SLC1A4 mRNA CTD PMID:25270620 NCBI chr11:20,302,180...20,332,713
Ensembl chr11:20,302,180...20,332,713
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 decreases expression ISO diethyl maleate results in decreased expression of SLC2A2 mRNA CTD PMID:21161181 NCBI chr 3:28,697,903...28,728,361
Ensembl chr 3:28,697,903...28,731,359
JBrowse link
G Slc2a5 solute carrier family 2 (facilitated glucose transporter), member 5 decreases expression ISO diethyl maleate results in decreased expression of SLC2A5 mRNA CTD PMID:21161181 NCBI chr 4:150,119,344...150,144,168
Ensembl chr 4:150,119,283...150,144,169
JBrowse link
G Slc39a14 solute carrier family 39 (zinc transporter), member 14 decreases expression EXP diethyl maleate results in decreased expression of SLC39A14 mRNA CTD PMID:25270620 NCBI chr14:70,303,467...70,351,452
Ensembl chr14:70,303,469...70,351,425
JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 multiple interactions ISO diethyl maleate inhibits the reaction [Lipopolysaccharides results in decreased expression of SLC40A1 mRNA] CTD PMID:21303654 NCBI chr 1:45,908,070...45,926,532
Ensembl chr 1:45,908,068...45,926,523
JBrowse link
G Slc44a4 solute carrier family 44, member 4 decreases expression ISO diethyl maleate results in decreased expression of SLC44A4 mRNA CTD PMID:21161181 NCBI chr17:34,914,224...34,930,436
Ensembl chr17:34,914,466...34,930,436
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 multiple interactions
increases expression
EXP NFE2L2 gene mutant form inhibits the reaction [diethyl maleate results in increased expression of SLC7A11 mRNA] CTD PMID:12235164 NCBI chr 3:50,364,936...50,499,087
Ensembl chr 3:49,892,526...50,443,614
JBrowse link
G Slc9a3r1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 decreases expression ISO diethyl maleate results in decreased expression of SLC9A3R1 mRNA CTD PMID:21161181 NCBI chr11:115,163,341...115,181,178
Ensembl chr11:115,163,341...115,181,181
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 decreases expression ISO diethyl maleate results in decreased expression of SLCO2A1 mRNA CTD PMID:21161181 NCBI chr 9:103,007,061...103,096,002
Ensembl chr 9:102,988,712...103,096,002
JBrowse link
G Slfn3 schlafen 3 decreases expression ISO diethyl maleate results in decreased expression of SLFN3 mRNA CTD PMID:21161181 NCBI chr11:83,191,330...83,215,154
Ensembl chr11:83,191,330...83,215,154
JBrowse link
G Smc4 structural maintenance of chromosomes 4 increases expression ISO diethyl maleate results in increased expression of SMC4 mRNA CTD PMID:21161181 NCBI chr 3:69,004,738...69,034,623
Ensembl chr 3:69,004,738...69,034,623
JBrowse link
G Smtn smoothelin increases expression ISO diethyl maleate results in increased expression of SMTN mRNA CTD PMID:21161181 NCBI chr11:3,517,522...3,539,292
Ensembl chr11:3,517,523...3,540,612
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression EXP diethyl maleate results in decreased expression of SOCS3 mRNA CTD PMID:25270620 NCBI chr11:117,966,079...117,970,336
Ensembl chr11:117,966,079...117,970,047
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Sorl1 sortilin-related receptor, LDLR class A repeats-containing decreases expression ISO diethyl maleate results in decreased expression of SORL1 mRNA CTD PMID:21161181 NCBI chr 9:41,964,709...42,124,297
Ensembl chr 9:41,964,720...42,124,297
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 increases expression ISO diethyl maleate results in increased expression of SOX9 mRNA CTD PMID:21161181 NCBI chr11:112,782,210...112,787,757
Ensembl chr11:112,782,224...112,787,760
JBrowse link
G Sp5 trans-acting transcription factor 5 decreases expression EXP diethyl maleate results in decreased expression of SP5 mRNA CTD PMID:25270620 NCBI chr 2:70,474,923...70,477,726
Ensembl chr 2:70,474,923...70,477,729
JBrowse link
G Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) increases expression ISO diethyl maleate results in increased expression of SPC25 mRNA CTD PMID:21161181 NCBI chr 2:69,193,895...69,206,213
Ensembl chr 2:69,193,895...69,206,194
JBrowse link
G Spta1 spectrin alpha, erythrocytic 1 increases expression EXP diethyl maleate results in increased expression of SPTA1 mRNA CTD PMID:25270620 NCBI chr 1:174,172,739...174,248,449
Ensembl chr 1:174,172,776...174,248,450
JBrowse link
G Sptan1 spectrin alpha, non-erythrocytic 1 increases cleavage ISO diethyl maleate results in increased cleavage of SPTAN1 protein CTD PMID:21105742 NCBI chr 2:29,965,560...30,031,451
Ensembl chr 2:29,965,560...30,031,451
JBrowse link
G Sptbn4 spectrin beta, non-erythrocytic 4 increases expression EXP diethyl maleate results in increased expression of SPTBN4 mRNA CTD PMID:25270620 NCBI chr 7:27,356,383...27,447,704
Ensembl chr 7:27,356,383...27,447,686
JBrowse link
G Sqstm1 sequestosome 1 increases expression EXP diethyl maleate results in increased expression of SQSTM1 mRNA CTD PMID:25270620 NCBI chr11:50,200,152...50,210,820
Ensembl chr11:50,199,366...50,210,827
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO diethyl maleate results in decreased expression of SREBF1 mRNA CTD PMID:21161181 NCBI chr11:60,199,084...60,224,186
Ensembl chr11:60,199,089...60,222,581
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) multiple interactions
increases expression
EXP
ISO
[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]; NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]
NFE2L2 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
diethyl maleate results in increased expression of SRXN1 mRNA; diethyl maleate results in increased expression of SRXN1 protein
CTD PMID:22003191 PMID:25270620 PMID:27358234 PMID:27982581 NCBI chr 2:152,105,524...152,111,376
Ensembl chr 2:152,105,516...152,111,376
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO diethyl maleate results in decreased expression of STAT1 mRNA CTD PMID:21161181 NCBI chr 1:52,119,438...52,161,865
Ensembl chr 1:52,119,440...52,161,865
JBrowse link
G Steap4 STEAP family member 4 decreases expression EXP diethyl maleate results in decreased expression of STEAP4 mRNA CTD PMID:25270620 NCBI chr 5:7,960,472...7,982,213
Ensembl chr 5:7,960,457...7,982,213
JBrowse link
G Sulf2 sulfatase 2 decreases expression ISO diethyl maleate results in decreased expression of SULF2 mRNA CTD PMID:21161181 NCBI chr 2:166,073,899...166,155,683
Ensembl chr 2:166,073,089...166,155,663
JBrowse link
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 decreases expression ISO diethyl maleate results in decreased expression of SULT1A1 protein CTD PMID:21161181 NCBI chr 7:126,672,865...126,690,443
Ensembl chr 7:126,672,865...126,676,432
JBrowse link
G Tagln transgelin decreases expression ISO diethyl maleate results in decreased expression of TAGLN mRNA CTD PMID:21161181 NCBI chr 9:45,929,628...45,936,058
Ensembl chr 9:45,929,619...45,936,058
JBrowse link
G Tbcel tubulin folding cofactor E-like increases expression EXP diethyl maleate results in increased expression of TBCEL mRNA CTD PMID:25270620 NCBI chr 9:42,412,316...42,472,238
Ensembl chr 9:42,412,316...42,507,809
JBrowse link
G Tent5a terminal nucleotidyltransferase 5A decreases expression ISO diethyl maleate results in decreased expression of TENT5A mRNA CTD PMID:21161181 NCBI chr 9:85,320,439...85,327,150
Ensembl chr 9:85,320,439...85,327,348
JBrowse link
G Tesmin testis expressed metallothionein like affects localization EXP diethyl maleate affects the localization of TESMIN protein CTD PMID:12606435 NCBI chr19:3,388,857...3,407,823
Ensembl chr19:3,388,857...3,407,823
JBrowse link
G Tfeb transcription factor EB decreases expression EXP diethyl maleate results in decreased expression of TFEB mRNA CTD PMID:25270620 NCBI chr17:47,737,037...47,792,416
Ensembl chr17:47,737,030...47,792,419
JBrowse link
G Tgm2 transglutaminase 2, C polypeptide increases expression ISO diethyl maleate results in increased expression of TGM2 mRNA CTD PMID:21161181 NCBI chr 2:158,116,405...158,146,392
Ensembl chr 2:158,116,402...158,146,436
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO diethyl maleate results in increased expression of THBS1 mRNA CTD PMID:21161181 NCBI chr 2:118,111,876...118,127,133
Ensembl chr 2:118,111,876...118,127,133
JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO diethyl maleate results in decreased expression of THRSP mRNA CTD PMID:21161181 NCBI chr 7:97,412,933...97,417,550
Ensembl chr 7:97,412,938...97,417,730
JBrowse link
G Tm4sf1 transmembrane 4 superfamily member 1 increases expression ISO diethyl maleate results in increased expression of TM4SF1 mRNA CTD PMID:21161181 NCBI chr 3:57,285,611...57,387,736
Ensembl chr 3:57,285,611...57,301,988
JBrowse link
G Tmem209 transmembrane protein 209 increases expression EXP diethyl maleate results in increased expression of TMEM209 mRNA CTD PMID:25270620 NCBI chr 6:30,481,022...30,509,787
Ensembl chr 6:30,479,053...30,509,783
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 protein; diethyl maleate inhibits the reaction [[carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]] which results in increased glutathionylation of RELA protein]; diethyl maleate inhibits the reaction [carnosol inhibits the reaction [TNF protein affects the localization of RELA protein]]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of SOD2 protein]
diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of diethyl maleate]
diethyl maleate inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; diethyl maleate inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]]; TNF protein promotes the reaction [diethyl maleate results in increased phosphorylation of JUN protein]
CTD PMID:7476933 PMID:7532384 PMID:12774022 PMID:20116392 PMID:31958493 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) decreases expression ISO diethyl maleate results in decreased expression of TNFRSF14 mRNA CTD PMID:21161181 NCBI chr 4:154,918,487...154,928,620
Ensembl chr 4:154,921,933...154,928,563
JBrowse link
G Tpm2 tropomyosin 2, beta decreases expression ISO diethyl maleate results in decreased expression of TPM2 mRNA CTD PMID:21161181 NCBI chr 4:43,513,726...43,523,583
Ensembl chr 4:43,514,711...43,523,765
JBrowse link
G Trap1 TNF receptor-associated protein 1 multiple interactions
decreases response to substance
ISO diethyl maleate inhibits the reaction [Cisplatin results in decreased expression of TRAP1 protein]
TRAP1 protein results in decreased susceptibility to diethyl maleate
CTD PMID:17853063 NCBI chr16:4,039,971...4,077,840
Ensembl chr16:4,039,971...4,077,827
JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 decreases expression EXP diethyl maleate results in decreased expression of TRDMT1 mRNA CTD PMID:25270620 NCBI chr 2:13,504,879...13,544,797
Ensembl chr 2:13,509,014...13,544,668
JBrowse link
G Trf transferrin decreases expression ISO diethyl maleate results in decreased expression of TF protein CTD PMID:21161181 NCBI chr 9:103,208,876...103,230,286
Ensembl chr 9:103,204,001...103,230,444
JBrowse link
G Trim6 tripartite motif-containing 6 decreases expression ISO diethyl maleate results in decreased expression of TRIM6 mRNA CTD PMID:21161181 NCBI chr 7:104,218,795...104,235,152
Ensembl chr 7:104,218,793...104,235,152
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 increases expression ISO diethyl maleate results in increased expression of TRIP13 mRNA CTD PMID:21161181 NCBI chr13:73,912,450...73,937,795
Ensembl chr13:73,911,347...73,937,784
JBrowse link
G Trp53 transformation related protein 53 multiple interactions EXP
ISO
TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA]
TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]; TP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]
CTD PMID:22003191 PMID:27982581 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression ISO diethyl maleate results in decreased expression of TSC22D1 mRNA CTD PMID:21161181 NCBI chr14:76,414,961...76,507,765
Ensembl chr14:76,414,961...76,507,765
JBrowse link
G Tspan8 tetraspanin 8 decreases expression ISO diethyl maleate results in decreased expression of TSPAN8 mRNA CTD PMID:21161181 NCBI chr10:115,816,817...115,849,893
Ensembl chr10:115,816,832...115,849,893
JBrowse link
G Tstd1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 decreases expression EXP diethyl maleate results in decreased expression of TSTD1 mRNA CTD PMID:25270620 NCBI chr 1:171,419,033...171,420,352
Ensembl chr 1:171,418,872...171,420,352
JBrowse link
G Txn1 thioredoxin 1 decreases activity ISO diethyl maleate results in decreased activity of TXN protein CTD PMID:15388247 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO diethyl maleate results in increased expression of TXNIP mRNA CTD PMID:21161181 NCBI chr 3:96,557,957...96,561,857
Ensembl chr 3:96,557,957...96,561,883
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO diethyl maleate results in increased expression of TXNRD1 mRNA CTD PMID:15521073 NCBI chr10:82,833,951...82,897,724
Ensembl chr10:82,833,951...82,897,712
JBrowse link
G Ubd ubiquitin D decreases expression ISO diethyl maleate results in decreased expression of UBD mRNA CTD PMID:21161181 NCBI chr17:37,193,892...37,196,101
Ensembl chr17:37,193,892...37,196,095
JBrowse link
G Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35 increases expression EXP diethyl maleate results in increased expression of UGT2B35 mRNA CTD PMID:25270620 NCBI chr 5:87,000,860...87,013,274
Ensembl chr 5:87,000,860...87,013,275
JBrowse link
G Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 increases expression ISO diethyl maleate results in increased expression of UHRF1 mRNA CTD PMID:21161181 NCBI chr17:56,303,337...56,323,486
Ensembl chr17:56,303,321...56,323,486
JBrowse link
G Usp18 ubiquitin specific peptidase 18 decreases expression ISO diethyl maleate results in decreased expression of USP18 mRNA CTD PMID:21161181 NCBI chr 6:121,245,906...121,270,917
Ensembl chr 6:121,245,906...121,270,917
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression ISO diethyl maleate results in decreased expression of USP2 mRNA CTD PMID:21161181 NCBI chr 9:44,067,021...44,095,627
Ensembl chr 9:44,067,021...44,095,627
JBrowse link
G Wdr31 WD repeat domain 31 decreases expression EXP diethyl maleate results in decreased expression of WDR31 mRNA CTD PMID:25270620 NCBI chr 4:62,448,653...62,470,999
Ensembl chr 4:62,448,653...62,470,896
JBrowse link
G Wdr6 WD repeat domain 6 decreases expression ISO diethyl maleate results in decreased expression of WDR6 mRNA CTD PMID:21161181 NCBI chr 9:108,572,311...108,578,713
Ensembl chr 9:108,572,311...108,578,739
JBrowse link
G Ypel5 yippee like 5 increases expression EXP diethyl maleate results in increased expression of YPEL5 mRNA CTD PMID:25270620 NCBI chr17:72,836,628...72,850,444
Ensembl chr17:72,836,453...72,851,195
JBrowse link
G Zfp36 zinc finger protein 36 increases expression ISO diethyl maleate results in increased expression of ZFP36 protein CTD PMID:21969073 NCBI chr 7:28,376,784...28,379,228
Ensembl chr 7:28,376,784...28,380,253
JBrowse link
G Zfp367 zinc finger protein 367 increases expression ISO diethyl maleate results in increased expression of ZNF367 mRNA CTD PMID:21161181 NCBI chr13:64,133,022...64,153,199
Ensembl chr13:64,133,018...64,153,202
JBrowse link
G Zfp37 zinc finger protein 37 decreases expression ISO diethyl maleate results in decreased expression of ZFP37 mRNA CTD PMID:21161181 NCBI chr 4:62,189,537...62,209,129
Ensembl chr 4:62,189,540...62,231,047
JBrowse link
G Zfp493 zinc finger protein 493 decreases reduction EXP diethyl maleate results in decreased reduction of ZFP493 protein CTD PMID:19843705 NCBI chr13:67,779,693...67,789,082
Ensembl chr13:67,779,693...67,792,512
JBrowse link
G Znrd2 zinc ribbon domain containing 2 decreases expression EXP diethyl maleate results in decreased expression of ZNRD2 mRNA CTD PMID:25270620 NCBI chr19:5,730,306...5,731,732
Ensembl chr19:5,728,088...5,731,713
Ensembl chr19:5,728,088...5,731,713
JBrowse link
dimethyl fumarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin, alpha 2, smooth muscle, aorta multiple interactions ISO Dimethyl Fumarate inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:30703375 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Atp6v0d2 ATPase, H+ transporting, lysosomal V0 subunit D2 multiple interactions EXP Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA] CTD PMID:30742845 NCBI chr 4:19,876,838...19,922,566
Ensembl chr 4:19,876,841...19,922,605
JBrowse link
G Bach1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 affects localization ISO Dimethyl Fumarate affects the localization of BACH1 protein CTD PMID:27277809 NCBI chr16:87,698,954...87,733,346
Ensembl chr16:87,698,945...87,733,346
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions
decreases expression
ISO
EXP
Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Dimethyl Fumarate inhibits the reaction [IKBKB protein results in increased expression of CCL2 mRNA]; Dimethyl Fumarate inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to CCL2 promoter]]; Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
Dimethyl Fumarate inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CCL2 mRNA]
Dimethyl Fumarate results in decreased expression of CCL2 mRNA
CTD PMID:26683377 PMID:27277809 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Cd68 CD68 antigen multiple interactions EXP Dimethyl Fumarate inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CD68 mRNA] CTD PMID:27277809 NCBI chr11:69,664,213...69,666,170
Ensembl chr11:69,664,213...69,666,153
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA]; Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] CTD PMID:30742845 NCBI chr18:61,105,572...61,131,139
Ensembl chr18:61,100,598...61,132,149
JBrowse link
G Ctsk cathepsin K multiple interactions EXP Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] CTD PMID:30742845 NCBI chr 3:95,499,210...95,509,387
Ensembl chr 3:95,499,256...95,509,362
JBrowse link
G Fth1 ferritin heavy polypeptide 1 multiple interactions
increases expression
ISO NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTH1 mRNA]
Dimethyl Fumarate results in increased expression of FTH1 mRNA; Dimethyl Fumarate results in increased expression of FTH1 protein
CTD PMID:28289076 NCBI chr19:9,980,600...9,985,111
Ensembl chr19:9,980,598...9,985,098
JBrowse link
G Ftl1 ferritin light polypeptide 1 multiple interactions
increases expression
ISO NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTL mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTL protein]
Dimethyl Fumarate results in increased expression of FTL mRNA; Dimethyl Fumarate results in increased expression of FTL protein
CTD PMID:28289076 NCBI chr 7:45,457,944...45,459,886
Ensembl chr 7:45,457,944...45,459,884
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
EXP
ISO
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLC mRNA]
Dimethyl Fumarate results in increased expression of GCLC protein
CTD PMID:27277809 PMID:30248482 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression
multiple interactions
ISO
EXP
Dimethyl Fumarate results in increased expression of GCLM protein
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLM mRNA]
CTD PMID:27277809 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Gpx4 glutathione peroxidase 4 increases metabolic processing ISO Dimethyl Fumarate results in increased metabolism of GPX4 protein CTD PMID:29917289 NCBI chr10:80,047,166...80,056,439
Ensembl chr10:80,047,166...80,056,439
JBrowse link
G Gsr glutathione reductase increases expression
multiple interactions
ISO