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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:malvidin
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Accession:CHEBI:6674 term browser browse the term
Definition:An anthocyanidin cation that is delphinidin carrying methyl substituents at positions 3' and 5'.
Synonyms:exact_synonym: 3,5,7-trihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromenium
 related_synonym: 3',5'-Dimethoxy-3,4',5,7-tetrahydroxyflavylium acid anion;   Formula=C17H15O7;   InChI=1S/C17H14O7/c1-22-14-3-8(4-15(23-2)16(14)21)17-12(20)7-10-11(19)5-9(18)6-13(10)24-17/h3-7H,1-2H3,(H3-,18,19,20,21)/p+1;   InChIKey=KZMACGJDUUWFCH-UHFFFAOYSA-O;   SMILES=COc1cc(cc(OC)c1O)-c1[o+]c2cc(O)cc(O)c2cc1O
 xref: Beilstein:1691742;   CAS:10463-84-0;   KEGG:C08716;   KNApSAcK:C00020647;   LIPID_MAPS_instance:LMPK12010004
 xref_mesh: MESH:C065861
 xref: MetaCyc:CPD-15051;   PMID:23755222;   Reaxys:1691742;   Wikipedia:Malvidin
 cyclic_relationship: is_conjugate_acid_of CHEBI:144781


show annotations for term's descendants           Sort by:
malvidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:23755222 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP malvidin results in increased expression of BAX protein CTD PMID:15964118 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP malvidin results in decreased expression of BCL2 protein CTD PMID:15964118 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions		 EXP malvidin results in increased activity of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [malvidin results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [malvidin results in increased activity of CASP3 protein]		 CTD PMID:15964118 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions ISO malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 mRNA]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 protein] CTD PMID:23755222 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions ISO malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein] CTD PMID:23755222 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation EXP malvidin results in decreased phosphorylation of MAPK1 protein CTD PMID:15964118 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions EXP malvidin results in increased expression of and results in increased phosphorylation of MAPK14 protein CTD PMID:15964118 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases phosphorylation EXP malvidin results in decreased phosphorylation of MAPK3 protein CTD PMID:15964118 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage EXP malvidin results in increased cleavage of PARP1 protein CTD PMID:15964118 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDE5A phosphodiesterase 5A decreases activity EXP malvidin results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804 		JBrowse link
G PDGFA platelet derived growth factor subunit A multiple interactions EXP malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296 		JBrowse link
G PDGFB platelet derived growth factor subunit B multiple interactions EXP malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO malvidin inhibits the reaction [endotoxin, Escherichia coli affects the localization of and results in increased phosphorylation of and results in increased activity of RELA protein] CTD PMID:23755222 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
malvidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP3 aquaporin 3 (Gill blood group) multiple interactions EXP [malvidin-3-glucoside co-treated with petunidin-3-glucoside] results in increased expression of AQP3 mRNA CTD PMID:33294640 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596 		JBrowse link
G CA1 carbonic anhydrase 1 decreases activity EXP malvidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA2 carbonic anhydrase 2 decreases activity EXP malvidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23731018 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PDE5A phosphodiesterase 5A decreases activity EXP malvidin-3-glucoside results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804 		JBrowse link
G SELE selectin E multiple interactions EXP malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:30611791 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO
EXP		 malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]		 CTD PMID:23731018 PMID:30611791 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
malvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CA1 carbonic anhydrase 1 decreases activity EXP malvin results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA2 carbonic anhydrase 2 decreases activity EXP malvin results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      biological role 25929
        biochemical role 25162
          metabolite 25092
            malvidin 20
              malvidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) 0
              malvidin 3-O-(6-O-(Z)-4-coumaroyl-beta-D-glucoside) 0
              malvidin 3-O-(6-O-acetyl-beta-D-glucoside) 0
              malvidin 3-O-\ 0
              malvidin 3-O-\ 0
              malvidin 3-O-beta-D-glucoside 7
              malvin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      carbon group element atom 25434
                        carbon atom 25403
                          organic molecular entity 25392
                            organic molecule 25222
                              organic cyclic compound 24274
                                organic heterocyclic compound 22328
                                  oxacycle 19986
                                    benzopyran 12738
                                      1-benzopyran 12474
                                        chromenes 4772
                                          chromene 136
                                            2H-chromene 136
                                              chromenyliums 136
                                                chromenylium 136
                                                  flavylium 136
                                                    anthocyanidin cation 136
                                                      5-hydroxyanthocyanidin 88
                                                        delphinidin 55
                                                          malvidin 20
                                                            malvidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) 0
                                                            malvidin 3-O-(6-O-(Z)-4-coumaroyl-beta-D-glucoside) 0
                                                            malvidin 3-O-(6-O-acetyl-beta-D-glucoside) 0
                                                            malvidin 3-O-\ 0
                                                            malvidin 3-O-\ 0
                                                            malvidin 3-O-beta-D-glucoside 7
                                                            malvin 2
paths to the root