CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: malvidin
Accession: CHEBI:6674
browse the term
Definition: An anthocyanidin cation that is delphinidin carrying methyl substituents at positions 3' and 5'.
Synonyms: exact_synonym: 3,5,7-trihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromenium
related_synonym: 3',5'-Dimethoxy-3,4',5,7-tetrahydroxyflavylium acid anion; Formula=C17H15O7; InChI=1S/C17H14O7/c1-22-14-3-8(4-15(23-2)16(14)21)17-12(20)7-10-11(19)5-9(18)6-13(10)24-17/h3-7H,1-2H3,(H3-,18,19,20,21)/p+1; InChIKey=KZMACGJDUUWFCH-UHFFFAOYSA-O; SMILES=COc1cc(cc(OC)c1O)-c1[o+]c2cc(O)cc(O)c2cc1O
xref: Beilstein:1691742; CAS:10463-84-0; KEGG:C08716; KNApSAcK:C00020647; LIPID_MAPS_instance:LMPK12010004
xref_mesh: MESH:C065861
xref: MetaCyc:CPD-15051; PMID:23755222; Reaxys:1691742; Wikipedia:Malvidin
cyclic_relationship: is_conjugate_acid_of CHEBI:144781
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Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD
PMID:23755222
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
malvidin results in increased expression of BAX protein
CTD
PMID:15964118
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
malvidin results in decreased expression of BCL2 protein
CTD
PMID:15964118
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Casp3
caspase 3
increases activity multiple interactions
ISO
malvidin results in increased activity of CASP3 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [malvidin results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [malvidin results in increased activity of CASP3 protein]
CTD
PMID:15964118
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Dusp1
dual specificity phosphatase 1
multiple interactions
ISO
malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 mRNA]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 protein]
CTD
PMID:23755222
NCBI chr10:16,680,478...16,683,275
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Gsk3b
glycogen synthase kinase 3 beta
multiple interactions
ISO
malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein]
CTD
PMID:23755222
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Mapk1
mitogen activated protein kinase 1
decreases phosphorylation
ISO
malvidin results in decreased phosphorylation of MAPK1 protein
CTD
PMID:15964118
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk14
mitogen activated protein kinase 14
multiple interactions
ISO
malvidin results in increased expression of and results in increased phosphorylation of MAPK14 protein
CTD
PMID:15964118
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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Mapk3
mitogen activated protein kinase 3
decreases phosphorylation
ISO
malvidin results in decreased phosphorylation of MAPK3 protein
CTD
PMID:15964118
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
malvidin results in increased cleavage of PARP1 protein
CTD
PMID:15964118
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pde5a
phosphodiesterase 5A
decreases activity
ISO
malvidin results in decreased activity of PDE5A protein
CTD
PMID:15769121
NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
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Pdgfa
platelet derived growth factor subunit A
multiple interactions
ISO
malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]
CTD
PMID:16921400
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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Pdgfb
platelet derived growth factor subunit B
multiple interactions
ISO
malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]
CTD
PMID:16921400
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
malvidin inhibits the reaction [endotoxin, Escherichia coli affects the localization of and results in increased phosphorylation of and results in increased activity of RELA protein]
CTD
PMID:23755222
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Aqp3
aquaporin 3 (Gill blood group)
multiple interactions
ISO
[malvidin-3-glucoside co-treated with petunidin-3-glucoside] results in increased expression of AQP3 mRNA
CTD
PMID:33294640
NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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Car1
carbonic anhydrase 1
decreases activity
ISO
malvidin-3-glucoside results in decreased activity of CA1 protein
CTD
PMID:28445001
NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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Car2
carbonic anhydrase 2
decreases activity
ISO
malvidin-3-glucoside results in decreased activity of CA2 protein
CTD
PMID:28445001
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Nos2
nitric oxide synthase 2
multiple interactions
ISO
malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD
PMID:23731018
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Pde5a
phosphodiesterase 5A
decreases activity
ISO
malvidin-3-glucoside results in decreased activity of PDE5A protein
CTD
PMID:15769121
NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
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Sele
selectin E
multiple interactions
ISO
malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]
CTD
PMID:30611791
NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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Tnf
tumor necrosis factor
multiple interactions
ISO
malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]
CTD
PMID:23731018 PMID:30611791
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Car1
carbonic anhydrase 1
decreases activity
ISO
malvin results in decreased activity of CA1 protein
CTD
PMID:28445001
NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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Car2
carbonic anhydrase 2
decreases activity
ISO
malvin results in decreased activity of CA2 protein
CTD
PMID:28445001
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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