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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:malvidin
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Accession:CHEBI:6674 term browser browse the term
Definition:An anthocyanidin cation that is delphinidin carrying methyl substituents at positions 3' and 5'.
Synonyms:exact_synonym: 3,5,7-trihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromenium
 related_synonym: 3',5'-Dimethoxy-3,4',5,7-tetrahydroxyflavylium acid anion;   Formula=C17H15O7;   InChI=1S/C17H14O7/c1-22-14-3-8(4-15(23-2)16(14)21)17-12(20)7-10-11(19)5-9(18)6-13(10)24-17/h3-7H,1-2H3,(H3-,18,19,20,21)/p+1;   InChIKey=KZMACGJDUUWFCH-UHFFFAOYSA-O;   SMILES=COc1cc(cc(OC)c1O)-c1[o+]c2cc(O)cc(O)c2cc1O
 xref: Beilstein:1691742;   CAS:10463-84-0;   KEGG:C08716;   KNApSAcK:C00020647;   LIPID_MAPS_instance:LMPK12010004
 xref_mesh: MESH:C065861
 xref: MetaCyc:CPD-15051;   PMID:23755222;   Reaxys:1691742;   Wikipedia:Malvidin
 cyclic_relationship: is_conjugate_acid_of CHEBI:144781



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malvidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:23755222 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO malvidin results in increased expression of BAX protein CTD PMID:15964118 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO malvidin results in decreased expression of BCL2 protein CTD PMID:15964118 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO malvidin results in increased activity of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [malvidin results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [malvidin results in increased activity of CASP3 protein]
CTD PMID:15964118 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 mRNA]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 protein] CTD PMID:23755222 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein] CTD PMID:23755222 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO malvidin results in decreased phosphorylation of MAPK1 protein CTD PMID:15964118 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO malvidin results in increased expression of and results in increased phosphorylation of MAPK14 protein CTD PMID:15964118 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO malvidin results in decreased phosphorylation of MAPK3 protein CTD PMID:15964118 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO malvidin results in increased cleavage of PARP1 protein CTD PMID:15964118 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pde5a phosphodiesterase 5A decreases activity ISO malvidin results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO malvidin inhibits the reaction [endotoxin, Escherichia coli affects the localization of and results in increased phosphorylation of and results in increased activity of RELA protein] CTD PMID:23755222 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
malvidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [malvidin-3-glucoside co-treated with petunidin-3-glucoside] results in increased expression of AQP3 mRNA CTD PMID:33294640 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23731018 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Pde5a phosphodiesterase 5A decreases activity ISO malvidin-3-glucoside results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Sele selectin E multiple interactions ISO malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:30611791 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]
CTD PMID:23731018 PMID:30611791 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
malvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO malvin results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvin results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        biochemical role 19588
          metabolite 19574
            malvidin 20
              malvidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) 0
              malvidin 3-O-(6-O-(Z)-4-coumaroyl-beta-D-glucoside) 0
              malvidin 3-O-(6-O-acetyl-beta-D-glucoside) 0
              malvidin 3-O-\ 0
              malvidin 3-O-\ 0
              malvidin 3-O-beta-D-glucoside 7
              malvin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  oxacycle 17850
                                    benzopyran 11796
                                      1-benzopyran 11539
                                        chromenes 4420
                                          chromene 137
                                            2H-chromene 137
                                              chromenyliums 137
                                                chromenylium 137
                                                  flavylium 137
                                                    anthocyanidin cation 137
                                                      5-hydroxyanthocyanidin 88
                                                        delphinidin 55
                                                          malvidin 20
                                                            malvidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) 0
                                                            malvidin 3-O-(6-O-(Z)-4-coumaroyl-beta-D-glucoside) 0
                                                            malvidin 3-O-(6-O-acetyl-beta-D-glucoside) 0
                                                            malvidin 3-O-\ 0
                                                            malvidin 3-O-\ 0
                                                            malvidin 3-O-beta-D-glucoside 7
                                                            malvin 2
paths to the root