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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:panaxydol
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Accession:CHEBI:66723 term browser browse the term
Definition:An acetylenic compound that has formula C17H24O2.
Synonyms:exact_synonym: (3R)-8-[(2R,3S)-3-heptyloxiran-2-yl]oct-1-ene-4,6-diyn-3-ol
 related_synonym: Formula=C17H24O2;   InChI=1S/C17H24O2/c1-3-5-6-7-10-13-16-17(19-16)14-11-8-9-12-15(18)4-2/h4,15-18H,2-3,5-7,10,13-14H2,1H3/t15-,16+,17-/m1/s1;   InChIKey=GVLDSGIQZAFIAN-IXDOHACOSA-N;   SMILES=CCCCCCC[C@@H]1O[C@@H]1CC#CC#C[C@H](O)C=C
 xref: CAS:72800-72-7;   KNApSAcK:C00030922
 xref_mesh: MESH:C055778
 xref: PMID:2092947;   Reaxys:7926422



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panaxydol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein decreases secretion ISO panaxydol results in decreased secretion of AFP protein CTD PMID:19450571 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Alb albumin increases secretion ISO panaxydol results in increased secretion of ALB protein CTD PMID:19450571 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP panaxydol inhibits the reaction [Oxygen deficiency results in decreased expression of BDNF mRNA]; panaxydol inhibits the reaction [Oxygen deficiency results in decreased secretion of BDNF protein]; panaxydol results in increased expression of and results in increased secretion of BDNF protein CTD PMID:18541227 PMID:18805406 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Casp3 caspase 3 multiple interactions EXP panaxydol inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein] CTD PMID:18541227 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO panaxydol results in increased expression of CDKN1A mRNA; panaxydol results in increased expression of CDKN1A protein CTD PMID:19450571 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO panaxydol results in decreased expression of ID1 mRNA CTD PMID:19450571 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO panaxydol results in decreased expression of ID2 mRNA CTD PMID:19450571 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ngf nerve growth factor multiple interactions
increases secretion
EXP panaxydol promotes the reaction [Oxygen deficiency results in increased expression of NGF mRNA]; panaxydol results in increased expression of and results in increased secretion of NGF protein
panaxydol results in increased secretion of NGF protein
CTD PMID:18541227 PMID:18805406 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases expression ISO panaxydol results in increased expression of RB1 protein; panaxydol results in increased expression of RB1 protein modified form CTD PMID:19450571 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    chemical entity 20049
      molecular entity 20047
        main group molecular entity 19948
          gas molecular entity 18247
            oxirane 9778
              epoxide 9777
                panaxydol 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            organic molecule 19809
                              organic cyclic compound 19572
                                organic heterocyclic compound 18799
                                  organic heteromonocyclic compound 17157
                                    saturated organic heteromonocyclic parent 9807
                                      oxirane 9778
                                        epoxide 9777
                                          panaxydol 9
paths to the root